Publications

covert fi- r factors in fi+ r+ strains of bacteria.	the presence of an fi(-) sex factor can be detected by propagation of the i-specific phage if1. by use of this method of detection, a high proportion of strains with fi(+) r factors were shown also to carry an fi(-) factor which was frequently a second r factor. in some doubly r(+) strains, the fi(+) and the fi(-) factor were observed to be transferred independently at conjugation.	1969	4886294
the filamentous phages fd and if1 use different mechanisms to infect escherichia coli.	the filamentous phage fd uses its gene 3 protein (g3p) to target escherichia coli cells in a two-step process. first, the n2 domain of g3p attaches to an f pilus, and then the n1 domain binds to tola-c. n1 and n2 are tightly associated, rendering the phage robust but noninfectious because the binding site for tola-c is buried at the domain interface. binding of n2 to the f pilus initiates partial unfolding, domain disassembly, and prolyl cis-to-trans isomerization in the hinge between n1 and n2. ...	2010	21110981