Publications

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implantation of b. coli into the human intestine. 195114860945
further observations on the persistence of individual strains of escherichia coli in the intestinal tract of man. 195214927548
antigenic relationships between h antigens 1-22 of e. coli and wramby's h antigens 23w-36w;11 new h antigens: 23-33. 195313079780
determination of vitamin b12 in human serum by a mutant of escherichia coli. 195413237290
experimental diarrheal disease of human volunteers due to escherichia coli. 195613395240
[study of gastroenteritis caused by escherichia coli pathogenes in young infant. iii. influence of maternal milk]. 195713494388
production of b character on human erythrocytes by haemosensitization with purified escherichia coli o 86 substance. 196113683140
studies on the inactivation of bacterial viruses by normal human serum. 6. comparative studies of various phages and of individual sera of human and animal origin. 196113750957
sialic acids (n,7-o-diacetylneuraminic acid and n-acetylneuraminic adcid) in escherichia coli. ii. their presence on the cell wall surface and relationship to k antigen.dewitt, charles w. (the upjohn co., kalamazoo, mich.) and elizabeth a. zell. sialic acids (n,7-o-diacetylneuraminic acid and n-acetylneuraminic acid) in escherichia coli. ii. their presence on the cell wall surface and relationship to k antigen. j. bacteriol. 82:849-856. 1961.-sialic acids obtained from escherichia coli by weak acid hydrolysis are shown to be released from the extreme-surface, lipoprotein layer of the cell. hydrolysis does not lyse the cells nor release cell walls. hydrolysates ...196113885922
problems of escherichia coli in animals and man. 196117421395
opportunistic gram-negative rod pulmonary infections. 196314042853
normal flora of the nose, throat, and lower intestine of dogs.clapper, w. e. (the lovelace foundation for medical education and research, albuquerque, n.m.) and g. h. meade. normal flora of the nose, throat, and lower intestine of dogs. j. bacteriol. 85:643-648. 1963.-an attempt was made to isolate and identify the complete normal flora of the rectum, nose, and throat of beagles. for primary isolation, 12 different kinds of media were used. incubation of blood agar plates and slants anaerobically, and of thioglycolate broth aerobically, allowed the growth ...196314042944
viability of coliform bacteria in antarctic soil.boyd, william l. (ohio state university, columbus) and josephine w. boyd. viability of coliform bacteria in antarctic soil. j. bacteriol. 85:1121-1123. 1963.-the distribution of coliform bacteria in soils of ross island and the nearby mainland was studied. none was found in almost all of the samples collected, including some from the adelie penguin rookeries at cape royds and cape crozier and in soil at the mcmurdo base which had been recently contaminated by human sewage. samples of pony manure ...196314044003
colicinogenic enterobacteria in human and animal faeces. 196314050551
[clinical experiences with the intestinal antibacterial activity of 2acetamido-4-(5-nitro-2-furyl)-thiazole]. 196314056619
the human skin as a source of mima-herellea infections. 196314064241
immunobacterial defense mechanisms in the human being during shock. 196314064526
[effect of respiratory virus infections on the course of gastrointestinal diseases in children]. 196314069398
on vitamin b12 forms in human plasma. 196314089259
inhibition of the bactericidal activity of human sera by wide-spectrum antibiotics. 196314274994
[etiology, pathogenesis and prevention of nutritional methemoglobinemia in breast-fed infants]. 196314187241
[study on the antibacterial activity in vitro and on the absorption, diffusion and elimination in man of 6(d(-)-alpha-aminophenylacetamido)penicillanic acid]. 196314097440
[microbiological studies on the problem of chloramphenicol stability in human milk. a contribution to the therapy of puerperal mastitis]. 196314107151
[on iatrogenic changes in otoantritis in infancy]. 196314121964
storage of mycoplasma strains.kelton, william h. (national animal disease laboratory, ames, iowa). storage of mycoplasma strains. j. bacteriol. 87:588-592. 1964.-survival of mycoplasma strains (19 of avian origin, 3 human, 3 canine, and 1 saprophyte) in the lyophilized state and at various storage temperatures was studied. the effect of alternate freezing and thawing was also studied. all strains survived the freeze-drying process and at least 3 or 4 years of storage in the lyophilized state. at -26 c, they survived for at l ...196414127574
studies on diarrheal diseases. the multiplicity of infectious agents in the intestinal flora of puerto rican children with gastroenteritis. 196414178831
[the capability of coliform microbes isolated from human faeces and drinking waters to utilize sugars in higher cultivating temperatures]. 196414193023
studies on viral inhibitors of biological origin. i. inhibition of viral replication by protein-like constituents of bacteria. 196414193398
[on the etiology of infantile diarrhea associated with a respiratory syndrome]. 196414196000
galactosidase action on human blood group b active escherichia coli and on red cell substances.the blood group b specificity of escherichia coli o(86) antigen, a b specific oligosaccharide fraction from it, and the b activity of a preparation of an "infectious mononucleosis receptor" from cattle erythrocytes are destroyed by alpha-galactosidase from the coffee bean, as demonstrated for the e. coli antigen by three methods. blood group h(o) activity appears simultaneously. galactose is the only hexose released from all three substances.196414202031
the serologic specificity of crude and purified antigen extracts of escherichia coli in hemagglutination reactions with rabbit and human antisera. 196414202246
acute diarrheal disease. 196414218165
studies on the human intestinal flora. i. the normal intestinal flora and the stability of its constituents. 196414230653
establishment of human indigenous bacteria in germ-free mice.gibbons, r. j. (forsyth dental center and harvard school of dental medicine, boston, mass.), s. s. socransky, and b. kapsimalis. establishment of human indigenous bacteria in germ-free mice. j. bacteriol. 88:1316-1323. 1964.-thirteen strains of bacteria indigenous to the gingival crevice area of man were tested for their ability to establish as monocontaminants in germ-free mice. three facultative organisms, streptococcus mitis, staphylococcus albus, and a "diphtheroid," established, as well as ...196414234787
diarrheal diseases of children. the occurrence of enteropathogenic viruses and bacteria. 196414095107
[clinical and bacteriological studies on the problem of colienteritis]. 196514240835
indirect fluorescent antibody technique in the serology of toxoplasma gondii.the indirect fluorescent antibody technique has been used to titrate patients' antibody against toxoplasma gondii. rigorous tests of the immunological validity of the method were made. the reactions of the gamma globulin of human immune serum with toxoplasma gondii and fluorescent rabbit anti-human gamma globulin were thus shown to be specific. thereafter the technique could be used with confidence to detect the reaction between doubling dilutions of patient's serum and smears of unfixed toxopla ...196514276154
the pathogenesis of strangulation obstruction. effect of hemoglobin on bactericidal capacity of human leukocytes. 196514296967
presence of polysaccharide-forming coliforms in human saliva. 196514304302
[on the problem of gamma globulin therapy of infectious diseases. passive mice immunity studies with human gamma globulin]. 19654161844
[simulation of human enteric infections in experiments on different animals]. 19654960842
[the antibacterial effect of the non-protein-bound part of sulfonamides in human plasma]. 19654961879
antibody to escherichia coli 0127 in human colostrum. 19665330251
relations between bacterial lipopolysaccharide structures and those of human cells. 19665336351
ultraviolet-induced colicines of escherichia coli from the normal human intestine. 19665337104
a sixty-nine year old man with severe diarrhea. 19674962595
in vitro and in vivo characterization of pyocin.pyocin, a bacteriocin obtained from lysates of ultraviolet-induced cultures of pseudomonas aeruginosa was characterized in vitro and in vivo after 1,000-fold purification by chemical, column, and differential centrifugation procedures. electron micrographs of negatively stained pyocin preparations contained rod-shaped particles which resembled the contractile tail protein of the t-even phages of escherichia coli. although two separate and distinct pyocin fractions were eluted from diethylaminoet ...19674960899
antibacterial activity of human prostatic fluid. 19674169341
inhibition of human serum bactericidal action by a chemical environment simulating the hydropenic renal medulla. 19674865230
viral depuration of the northern quahaug.a study was conducted to evaluate critically the feasibility of using the self-cleansing mechanism as a practical means to obtain virus-free shellfish. two systems supplied with fresh running seawater, three strains of human enterovirus and the northern quahaug, were used as working models. preliminary experiments in the experimental system under arbitrarily selected conditions showed that depuration of poliovirus-polluted quahaugs could be achieved by the method used for the eastern oyster. the ...19674291510
[some criteria of the detection of interrelationships between bacteria and viruses. 3. characteristics of respiration in intestinal bacterial in the adsorption of enteroviruses on them]. 19674299666
blood pyruvate and lactate during febrile human infections. 19684300353
[isolation of enterobacteriaceae and enteroviruses from normal children and children with acute diarrhea]. 19684304403
human placental alkaline phosphatase: molecular weight and subunit structure. 19684872644
septic shock. evaluation of the intradermal epinephrine test in diagnosis and of the effects of human plasma in potentiating coliform endotoxin. 19684876724
[antibody formation in vitro. ix. synthesis of informatory rna and antibodies in a cell free system from human peripheral leukocytes]. 19684882414
[persistence of r-factors in the human intestinal flora]. 19684915128
in vitro antimicrobial activity and human pharmacology of cephaloglycin.serum and urine concentrations of cephaloglycin (an orally absorbed derivative of cephalosporin c) were determined in normal volunteers and in patients. the in vitro activity of cephaloglycin was also studied. all strains of group a streptococci (streptococcus pyogenes) and diplococcus pneumoniae were inhibited by 0.4 mug of cephaloglycin per ml. eighty per cent of the staphylococcus aureus strains and about 50% of the escherichia coli and proteus mirabilis strains were inhibited by 1.6 mug of c ...19684385749
locus of the action of serum and the role of lysozyme in the serum bactericidal reaction.the mechanism of the lethal action of human serum on a rough strain of escherichia coli was investigated by use of serum with and without lysozyme, in medium of low and high osmotic pressure, with cells radioactively labeled in the peptidoglycan polymer, and by electron microscopy. the results suggested that there are two separate components in the bacterial cell wall that afford structural support for the cell. lysozyme attacked one of these, the peptidoglycan polymer. serum damaged the other, ...19684972918
[on the effect of antibodies on atpase activity and active na-k-transport of e. coli and human erythrocytes]. 19694390016
the influence of human serum on the anti-tumour activity of two l-asparaginases. 19694892234
ribonucleotide reductase in human bone marrow: lack of stimulation by 5'-deoxyadenosyl b 12. 19694893668
studies of intestinal microflora. 8. effect of lincomycin on the microbial population of the human intestine. 19694898413
effects in man and rabbits of inhalation of cotton dust or extracts and purified endotoxins. 19694899667
enzymatic release of phosphorus from human dental enamel by enzyme preparations of e. coli. a preliminary report. 19694901225
salmonella types isolated from the gulf of aarhus compared with types from infected human beings, animals, and feed products in denmark.a 2-year examination for salmonella was conducted in the gulf of aarhus, which receives waste water from local industries and from about 100,000 inhabitants. an approximately rectilinear relationship is shown between the most probable number of escherichia coli and species of salmonella. salmonella species can be demonstrated with the same frequency in inlets and outlets of the treatment plants. data on the distribution of salmonella types in the gulf of aarhus and in oeresound outside copenhage ...19694905700
[vi. species specificity of transfer rna and aminoacyl-transfer rna-synthetases from human tissues and e. coli]. 19704913978
inhibition of the cytoaggressive effect of phytohaemagglutinin (pha)-stimulated human lymphocytes by e. coli l-asparaginase (ec-2 a-se). 19704920638
[bacteriological studies of human ejaculates]. 19704922161
the presence of n2-fixing bacteria in the intestines of man and animals. 19704922762
mechanisms in protein synthesis. xii. sites of action of showdomycin in a cell-free polyphenylalanine synthesizing system from human lymphatic tissue: ribosomes and elongation factor tf ii. 19704933686
intraocular penetration of cephalexin in man. 19704392534
preparation of immunoglobulin concentrates from human serum by chromatography on controlled pore glass. 19704193150
nature and heterogeneity of the antigens of neisseria gonorrhoeae involved in the serum bactericidal reaction.sixty strains of neisseria gonorrhoeae have been classified into four main groups according to their resistance to killing by human complement together with either normal human or immune rabbit antibodies. the rabbit antisera had been raised against 10 of the strains tested. the normal human antibodies had probably been formed against cross-reacting organisms since they could be removed by absorption with n. pharyngis sicca, n. pharyngis flavus, n. catarrhalis, or escherichia coli. bactericidal ...197016557815
the microflora of the human integument during prolonged confinement.under conditions of long-term isolation in a sealed environment the microbial contamination of the skin and upper respiratory tract of man was much more pronounced than under normal conditions. this intensification of the contamination went on in a series of periodic increases in the amount of micro-organisms. every such increase in micro-organisms was much more prominent than the preceding one. the harmful nature of the rise of the level of microbial contamination of human epidermal tissues was ...197112206186
epicillin: in vitro laboratory studies.a new semisynthetic penicillin, structurally related to ampicillin, has been assigned the generic name epicillin, 6-[d-2-amino-2-(1, 4-cyclohexadienyl) acetamido]-penicillanic acid. the antimicrobial spectrum and level of activity of epicillin in vitro are similar to those of ampicillin. in studies with recent clinical isolates, these two antibiotics, when compared with carbenicillin, showed consistently higher antimicrobial activity against staphylococcus aureus, streptococcus pyogenes, escheri ...19714343402
ecology of intestinal escherichia coli in pigs.the coliflora of three groups of young pigs was shown to be dominated by a small number of escherichia coli types, as determined by their o antigen, that maintained a tenure of several days or weeks. the pattern of successive waves of e. coli was similar in littermates but, in general, each pig harboured a unique sequence of e. coli types. the e. coli flora from a litter was also shown to be dominated by a small number of e. coli types whose tenure averaged several weeks. a limited amount of inf ...19714260947
bacteriophage types and o antigen groups of escherichia coli from urine.urinary strains of escherichia coli from seven geographical regions were typed serologically for o-specific antigens and with phages capable of lysing the majority of urinary isolated. the o antigen groups 4, 6, 75, 1, 50, 7, and 25 were the common ones found. of the 454 cultures tested, 66.1% were phage typable and 65.2% were serotypable with the 48 antisera employed. also, 71.6% of the cultures for which an o group could be determined were phage typable. furthermore, of those seven o-antigen g ...19714939122
the uniqueness of human milk. 19714940973
[first successful transplantation of a gene into human cells with hereditary disease]. 19714941013
antigens common to human and bacterial cells: urinary tract pathogens. 19714942854
effects of multiple use on water quality of high-mountain watersheds: bacteriological investigations of mountain streams.bacteriological studies in 1968 and 1969 corroborated earlier findings that a municipal watershed which had been closed to public entry since 1917 yielded water with four to six times the coliform count found in an adjacent mountain watershed open to recreational activities. similarly, chemical investigations showed higher concentrations of most ions in water from the closed area. physiological differentiation of coliform and enterococcal bacteria revealed similar types of organisms in both anim ...19714944803
[in vitro sensitivity of human pathogens to the drug combination sulfamethoxazole-trimethoprim]. 19714946735
effects of a variety of endotoxins on human and rabbit platelet function. 19714947419
enteropathogenicity of escherichia coli. i. evaluation of mouse intestinal loops.a ligated mouse intestinal loop assay has been introduced to evaluate the enteropathogenicity of strains of escherichia coli. when inoculated as whole cultures, 19 (34%) of 55 strains isolated from diarrheic infants, each of 4 strains associated with diarrhea in human adults, and 5 of 7 strains associated with porcine coli bacillosis were found capable of causing fluid accumulation in this model. in contrast, only 1 of 28 strains isolated from normal individuals was positive in this test. steril ...19714949503
effect of endotoxemia on liver cell mitochondria in man. 19714950233
acute undifferentiated human diarrhea in the tropics. i. alterations in intestinal micrflora.the microflora of the small and large intestine was determined in 17 adults with acute undifferentiated diarrhea in calcutta, india. on the basis of bacteriologic findings, the patients could be divided into two groups: those with a predominant flora of escherichia coli (eight patients) and those with a mixed coliform flora (nine patients). in the former group, e. coli were distributed throughout the small and large bowel. broth filtrates of these isolates contained an enterotoxin which caused f ...19714926260
interference of human spermatozoa motility by escherichia coli. 19714930153
an analysis of the rapidly synthesized ribonucleic acid of the normal human lymphocyte by agarose-polyacrylamide gel electrophoresis. 19714931753
a technique for quantitative measurement of endotoxin in human plasma. 19714932052
tryptophanyl transfer rna synthetase from lymphocytes of human chronic lymphocytic leukemia. 19714932213
[current achievements in oral immunization]. 19714995665
platelet interaction with bacteria. ii. fate of the bacteria.several common strains of bacteria have been studied to determine their influence on human and rabbit platelets in vitro. bacteria at a nominal ratio of 1:1 were added to platelets in their native plasma or to platelets in a balanced salt solution. the platelet-bacterial interaction was examined by nephelometry and by sequential light microscopy of fixed specimens taken at key points in the reaction. the results support the following conclusions: (1) bacteria that were potent stimuli of the plat ...19715002629
antibacterial activity of dihydro-1,3-oxazine derivatives condensed with aromatic rings in positions 5,6.1. the antibacterial activity in vitro of dihydro-1,3-oxazine derivatives with aromatic rings condensed in positions 5, 6 was examined.2. of more than thirty compounds examined, two (t 615 and t 638) showed marked activity against various strains of mycobacterium tuberculosis at concentrations below 2 mug/ml.3. these two compounds also showed marked activity against escherichia coli, clostridium pneumoniae and salmonella typhi.4. both showed marked activity in vivo against tuberculosis produced ...19715003353
[microbiological relationships between man and laboratory animals]. 19715004293
human plasma and the antibacterial effect of peritoneal dialysis solutions.the influence of human plasma on the antibacterial effect of solutions for peritoneal dialysis was studied. the solutions contained 43 meq per litre of either acetate or lactate as the source of base. enough pooled human plasma was added to half of each solution to give a total concentration of a gramme of protein per litre. the numbers of viable organisms from 15 clinical isolates each of staphylococcus aureus, escherichia coli, and pseudomonas species were counted before and after incubation i ...19715541232
the hygiene and marketing of fresh cream as assessed by the methylene blue test. a report by a working party to the director of the public health laboratory service.the hygiene and marketing of fresh cream in england and wales was investigated by a working party of the public health laboratory service (phls) between 1 october 1968 and 31 july 1969. thirty-one cream-producing dairies were visited and observations made in the light of the code of practice published by the milk and milk products technical advisory committee of the ministry of agriculture, fisheries and food, and the scottish home and health department. suggestions are made in this report to st ...19714326247
the uniqueness of human milk. host resistance to infection.field observations are reported which support an assumption that human breast milk acts benefically through induced host resistance to infection. though the mechanisms of this induced host resistance to infection are not clearly understood, this article suggests the following factors as important: specific antibodies to infectious agents, influences stimulating or inhibiting certain intestinal microorganisms, and nonspecific antimicrobial factors. immunoglobulins are present in human milk, wit ...19714327608
electrophoretic analysis of ribosomal and viral ribonucleic acids with a simple technique for slicing low-concentration polyacrylamide gels.the electrophoretic mobilities of ribosomal ribonucleic acids (rna) from cultured mammalian (hela, vero, mdbk), avian (chick embryo), and bacterial (escherichia coli) cells, and rna species extracted from selected viruses (sindbis, polio, tobacco mosaic, sendai) were compared, employing a simple, inexpensive technique for slicing low-concentration polyacrylamide gels. the procedure provides for rapid fractionation of gels used for characterization of rna, incorporating extrusion and serial secti ...19714331767
bacterial inactivation of human serum alpha-1 antitrypsin. 19714104239
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