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detection of salmonella spp. in milk by using felix-o1 bacteriophage and high-pressure liquid chromatography.a method is described whereby the presence of less than five salmonellae was detected per milliliter of milk within 24 h of sample collection. salmonellae were removed from milk by means of electropositive large-pore filters. eluates from the filters were analyzed for the presence of salmonella spp. by felix-o1 bacteriophage and high-pressure liquid chromatographic techniques. the method gave only a positive response when salmonellae were present in the milk. of the serotypes and strains of salm ...19836360047
impaired bactericidal activity of cord sera against salmonella strains.weaker bactericidal activity of cord sera against salmonella bacilli was shown in comparison with maternal venous sera. no correlation was found between the bactericidal activity and the levels of complement, immunoglobulins and lysozyme in cord sera. worthy of notice is detected in these researches specificity of bactericidal action of cord sera.19836360075
enterotoxin production by salmonella enteritidis at various environmental conditions. 19836360858
the bactericidal and opsonic effects of serum from patients with sickle cell anaemia.the bactericidal and opsonic activity of serum from 12 homozygous sicklers was compared with that of a single control pool of healthy nonsickler african serum. factorially designed experiments were used to calculate 4 indices which were expressed as the ratio of test to control. using s. enteritidis and normal human neutrophils viability indices (vi) were calculated for serum, for ingested organisms and for cells + serum, together with a phagocytic index (pi) for cells. only 1 of the 12 sickler ...19836370481
[outbreak of food poisoning infection in orihuela (alicante)]. 19836393306
polymicrobial polyarticular septic arthritis.a bacteriology technologist was found to have acute polyarticular arthritis after a brief prodromal illness. gram's stain of fluid from the right knee showed pleomorphic gram-negative organisms, while that of fluid from the right elbow and left wrist showed gram-negative cocci and diplococci. culture of fluid from the right knee yielded salmonella enteritidis. cultures of fluid from all other joints, collected after starting therapy, were negative. an enzyme-linked immunosorbent assay of fluid f ...19836403721
a febrile dairy farmer with nausea and diarrhea. 19836406347
[basic studies on prevention of experimental salmonellosis. (6) cellular immunity in the protective mechanism with purified spa of salmonella enteritidis]. 19836406621
immunobiological activities of synthetic lipid a analogs and related compounds as compared with those of bacterial lipopolysaccharide, re-glycolipid, lipid a, and muramyl dipeptide.thirteen acylated and phosphorylated derivatives of beta-1,6-linked glucosamine disaccharide (lipid a analogs), which were synthesized after the structural model of salmonella-type lipid a, and seven similar derivatives of glucosamine monosaccharide (lipid a-related compounds) were studied for their immunobiological activities. these included mitogenicity and polyclonal b cell activation enhancement of migration of monocytes and polymorphonuclear leukocytes derived from human peripheral blood, s ...19836409812
[enteritis salmonella. epidemiologic status in the years 1953 to 1975 in humans and animals using as example southern bavaria]. 19836412079
paratyphoid orchitis.a case of pyogenic orchitis due to infection with salmonella enteritidis ser. paratyphi b is discussed. unlike previously reported cases of salmonella orchitis, this patient developed infection by bacteremic spread and not by direct extension from the epididymis. therapy with chloramphenicol resulted in an excellent clinical response.19836425004
artificial salmonella vaccines. 19836187015
in vitro effects of lipopolysaccharides and mycobacterial cell wall components on swine alveolar macrophages.the possible activation of swine alveolar macrophages (am) by lipopolysaccharides (lps) and mycobacterial cell wall components such as muramyl dipeptide (mdp) and interphase material (ipm) was investigated. swine am were harvested by post mortem lung washings and the following functions were assayed: adherence and spreading in cultures; phagocytosis of 51cr-labelled chicken red cells; cytostatic activity against xenogeneic tumour cells (p815 mastocytoma cells); monokine synthesis; interferon and ...19836190207
growth of various bacteria and yeast in a peptide and an element diet.solutions of a peptide and an elemental diet were artificially contaminated with several bacterial and yeast strains. their growth was measured after eight and 24 h incubation at 4 degrees and 22 degrees c. at 4 degrees c no increase in colony count could be observed in either diet within 24 h. at 22 degrees a significant increase of all but the campylobacter strains was obtained after 24 h in the peptide diet. in the elemental diet only the pseudomonas and the yeast strains showed a small incre ...19836190886
[lysine decarboxylase activity of s. enteritidis isolated from various sources]. 19836194339
degradation of cell constituents during starvation of salmonella enteritidis.salmonella enteritidis starved in fernbach flasks used acid-alcohol-soluble material and rna as endogenous reserves during starvation. organisms starved in a fermentor system consumed acid-alcohol-soluble material, rna and protein to maintain viability. half-life survival times were 132 h and 118 h for the fernbach and fermentor-starved cells, respectively. the acid-alcohol-soluble fraction of the cell consisted mainly of peptides or protein. this fraction accounted for most of the loss of label ...19846200750
identification of salmonella o antigens by coagglutination.this study concerns the preparation of reagents for identifying the somatic o antigens of salmonella enteritidis. coagglutination reagents (coags) with antibody fixed to killed and stabilized protein a-bearing staphylococci were prepared with antisera which were used for identifying the somatic o antigens of s. enteritidis by the slide agglutination test. the reactions of the coags were compared with those obtained with the grouping antisera in routine slide agglutination tests in which 41 or mo ...19846203928
role for calcium in the insulin hypersecretory state of the endotoxic rat pancreas.previous studies have demonstrated that the endotoxic rat pancreas hypersecretes insulin in response to a glucose stimulus. however, the mechanism for this phenomenon is unknown. since increases in pancreatic beta (b)-cell cytosolic ionic calcium are required for insulin secretion, this study evaluated the role of extracellular calcium on insulin secretion from the isolated, perfused endotoxic pancreas in the presence of and in the absence of extracellular calcium. isolated pancreas preparations ...19846207953
cefotaxime therapy of bacterial meningitis in children.thirty children with bacterial meningitis were randomized to receive either ampicillin and chloramphenicol in standard doses or cefotaxime (50 mg/kg/dose every 6 h) for 10 to 14 days. eighteen patients received ampicillin and chloramphenicol and 12 patients received cefotaxime. cerebrospinal fluid isolated included: haemophilus influenzae (20), streptococcus pneumoniae (4), neisseria meningitidis (3), group b streptococcus (2), and salmonella enteritidis (1). five of the h. influenzae isolates w ...19846094438
antibiotics and human defence mechanisms: the effects of ampicillin and cefotaxime on intra- and extracellular killing of salmonella enteritidis.in-vitro reaction mixtures were set up containing bacteria, human serum, human neutrophils and ampicillin or cefotaxime at the mic, mic/2 or mic/4. serum was untreated, heat-inactivated, absorbed or both. five indices measuring intra- and extracellular killing were calculated and the effects of heat-labile and absorbable serum factors and of the various concentrations of antibiotics on these indices were calculated. both heat-labile and absorbable factors enhanced intra- and extracellular killin ...19846094465
effect of muramyl dipeptide analog on salmonella enteritidis infection in beige mice with chediak-higashi syndrome.beige mutant (bg/bg) mice with chediak-higashi syndrome (chs) were much more sensitive to virulent salmonella enteritidis no. 11 strain than parental c57 bl/6 (+/+) or heterozygous (bg/+) mice, and they had weaker bactericidal activity against the organisms. muramyl dipeptide (mdp) and n alpha-(n-acetyl-muramyl-l-alanyl-d-isoglutamyl)-n epsilon-stearoyl-l-lysine [mdp-lys(l18)], a synthetic derivative of mdp, failed to confer any protection against the infection, but the mdps showed some ability ...19846097802
[a case of pneumonia due to salmonella enteritidis]. 19846434667
poultry giblet-associated salmonellosis--maine. 19846436665
in vitro and in vivo antibacterial activities of mt-141, a new semisynthetic cephamycin, compared with those of five cephalosporins.the in vitro and in vivo antibacterial activities of mt-141 were compared with those of cefoxitin, cefmetazole, moxalactam, cefotaxime, and cefoperazone. the mics of mt-141 for 90% of bacterial isolates were lower than the reference drugs against clinical isolates of campylobacter jejuni, clostridium difficile, and bacteroides fragilis, whereas against clinical isolates of other gram-positive, gram-negative, and anaerobic bacteria, the mics of mt-141 were similar to or higher than those of the r ...19846440478
the role of hypothalamic centres in the immune specific response.four groups of rats were bilaterally lesioned in the anterior, lateral, tuberal and mammillary areas of hypothalamus. seven days later these rats, as well as controls, were immunized concomitantly with three antigens: salmonella enteritidis, sheep red blood cells and myxovirus influenzae a (h3n2). the primary and the secondary response were tested. the bacterial and erythrocytic antigens, with marked immunogenetic capacity, produced immune responses, which were not significantly influenced by hy ...19846441174
antimicrobic effects of lactobacillus fermentation on edible waste material contaminated with infected carcasses.survival of newcastle disease virus (ndv) and salmonella enteritidis serovar typhimurium (introduced as infected carcasses) in lactobacillus-fermented edible waste material was studied to determine the ability of the fermentation to activate disease agents in carcasses. two trials were conducted. in the 1st trial, the fermented wastes contained 20% infected carcasses (protein) consisting of equal numbers of chicken (ndv) and rat (salmonella) carcasses, and the 2nd trial contained 40% carcasses ( ...19846441490
reticuloendothelial system function and glucose-insulin dyshomeostasis in sepsis.circulating glucose levels, peripheral glucose utilization, and hepatic gluconeogenesis were compared in late endotoxicosis and severe septic shock in rats. endotoxin was administered intravenously as 5 mg of salmonella enteritidis lipopolysaccharide b. sepsis was induced in the peritoneal cavity by use of the cecal ligation and puncture technique. late endotoxicosis and severe sepsis were comparable in hypoglycemia, increased peripheral glucose use, and depression of gluconeogenesis. immunoreac ...19846394000
[treatment with lactulose. a low-risk alternative in various diseases]. 19846394457
[rare types of osteomyelitis. bcg and salmonella osteomyelitis]. 19846395367
influence of antibiotics on growth, synthesis & release of enterotoxin by salmonella enteritidis. 19846396228
differential acute-phase responses in febrile and cold- and heat-exposed rabbits.endotoxin (lps) characteristically provokes both fever and the acute-phase reaction (apr). the present studies were undertaken to determine whether these two responses are mutually dependent or controlled separately. rabbits were injected with lps (2 micrograms/kg, iv) or exposed to heat (37 +/- 1 degree c) such that the patterns and magnitudes of the body temperature (tco) rises (1.6 +/- 0.5 degrees c) were similar. while the plasma levels of fe and zn decreased, and those of cu and n-acetylneu ...19846396576
salmonella mediastinitis--a rare disease.a case report is presented of a young man who was seen because of pleuritic chest pain and fever. ct cross sectional imaging defined a mediastinal mass. diagnosis of acute mediastinitis due to salmonella java was made from culturing material at mediastonotomy.19846397327
[incidence and clinical course of salmonella infections among children in the pÅ‚ock region 1976-1980]. 19846398468
bacteremia in hospitalized black south african children. a one-year study emphasizing nosocomial bacteremia and bacteremia in severely malnourished children.during a one-year period, 315 of 5,397 children admitted to the general pediatric wards of a hospital had bacteremia. the commonest causative organisms were streptococcus pneumoniae, salmonella enteritidis, hemophilus influenzae, and escherichia coli. most episodes of bacteremia were associated with gastroenteritis, pneumonia, or meningitis. seventy-eight episodes occurred in children with severe protein-energy malnutrition, and 46 episodes were hospital acquired. the overall case fatality rate ...19846372439
loss of hepatic venous responsiveness after endotoxin in anesthetized cats.endotoxin (from salmonella enteriditis ) was administered either as an intravenous bolus injection after administration of indomethacin to prevent the acute anaphylactoid response or as a slow intravenous infusion to cats anesthetized with pentobarbital. within 30 min, hepatic blood volume measured by plethysmography increased by 30%. however, unlike the outflow block seen in dogs after endotoxin, this increase in blood volume was associated with a fall in portal and hepatic lobar venous pressur ...19846372524
bactericidal activities of chloramphenicol and eleven other antibiotics against salmonella spp.the bactericidal activity of chloramphenicol against 27 strains of salmonella typhi and 33 strains of s. enteritidis was compared with those of 11 other antibiotics. the geometric mean bactericidal concentrations of chloramphenicol against susceptible strains (36.10 and 43.13 micrograms/ml for s. typhi and s. enteritidis, respectively) far exceeded those of the other 11 antibiotics, with cephalothin having the next highest values (2.67 and 8.66 micrograms/ml) and moxalactam (0.09 and 0.28 microg ...19846372681
viable but nonrecoverable stage of salmonella enteritidis in aquatic systems.an environmental isolate (13- 1bb ) of salmonella enteritidis serogroup c1 was inoculated into sterile potomac river water microcosms to observe survival and culturability of the organism by employing acridine orange direct count, fluorescent antibody direct count, direct viable count, plate count on veal infusion agar and xylose lysine decarboxylase agar, and indirect enumeration by the most-probable-number method (mpn), using media selective for salmonella. loss of culturability on laboratory ...19846372975
comparison of enterotoxin production by salmonella enteritidis in laboratory media, milk & meat. 19846373584
[pancreatitis associated with salmonella enteritidis bacteremia]. 19846374315
case records of the massachusetts general hospital. weekly clinicopathological exercises. case 24-1984. pancytopenia and fever in a renal-transplant recipient. 19846374453
[erythema nodosum and salmonella enteritidis gastroenteritis: a less uncommon association than is supposed?]. 19846376974
agglutinogens, white's 'q' substance and the common proteins of enterobacteriaceae.reassessment of the antigens involved in the cross-relation of enterobacteriaceae point to the common proteins first discovered by white (1932) and named substance q. all the serological characteristics of substance q, as described by white, are identical with those obtained with pure enterobacterial proteins.19846377018
non-typhoid salmonella infections after renal transplantation. a serious clinical problem.a retrospective study of 410 renal transplant recipients showed that 1.96% (8/410) of patients had developed severe non-typhoid salmonella infections. the clinical features seen were fever, leucopenia, pneumonia, diarrhoea, abscesses, pyelonephritis, venous thrombosis and pleural effusion. neither uraemia nor repeated high doses of steroids seemed to be major precipitating events. all isolates were strains of salmonella enteritidis. all 8 patients were cured and none became permanent carriers. s ...19846377104
nontyphoidal salmonella bacteremia as an early infection in acquired immunodeficiency syndrome.during a two-year period, two drug addicts and one homosexual patient with acquired immunodeficiency syndrome (aids) developed persistent salmonella typhimurium or s. enteritidis bacteremia early in the course of their syndrome. a fourth patient, also a male homosexual with recurrent s. typhimurium bacteremia and urinary tract infection, is being closely followed prospectively for the development of aids. nontyphoidal salmonella bacteremia appears to be an emerging problem in aids patients and m ...19846378505
augmentation of protective and antibacterial activity induced by muramyl dipeptides in cba/n defective mice with x-linked immunodeficiency for salmonella enteritidis infection.stimulation of resistance induced by muramyl dipeptide (mdp) and its analog, n alpha-mdp-n epsilon-stearoyl-l-lysine [mdp-lys(l18)], was examined in experimental salmonellosis in cba/n defective mice with x-linked immunodeficiency to virulent salmonella enteritidis no. 11. an injection of either mdp or mdp-lys(l18) did not induce any effective protection, but repeated injections of mdp-lys(l18) (100 micrograms per mouse per day for 3 days consecutively) to the mice before bacterial challenge gav ...19846378798
plasma therapy of primary rat mammary carcinoma: antitumor activity of tumor-bearer plasma adsorbed against inactivated cnbr sepharose or protein a-sepharose.we evaluated the ability of plasma adsorbed against sepharose, inactivated cnbr sepharose, or protein a-sepharose to inhibit the growth of primary mammary carcinomas in buffalo/n rats. mammary adenocarcinomas were induced by a single intravenous injection of n-nitroso n-methylurea. when palpable mammary tumors were detected, rats were treated by infusion of plasma obtained from normal or tumor-bearing rats. animals were killed 50 days after entry into the experiment; the index mammary tumor and ...19846379113
[mesenteric lymphadenitis caused by salmonella enteritidis]. 19846379334
[a strain of salmonella enteritidis isolated from pleural pus]. 19846379389
drug-resistant salmonella from animals fed antimicrobials.it has been difficult to document the postulated sequence of events that begins with the selection of drug-resistant organisms in animals fed subtherapeutic amounts of antimicrobials and ends with clinically important infections in human beings. in early 1983 we identified 18 persons in four midwestern states who were infected with salmonella newport that was resistant to ampicillin, carbenicillin, and tetracycline and characterized by a 38-kilobase r plasmid. twelve of these patients had been t ...19846382001
[salmonella infections in children]. 19846382140
classics in infectious diseases. toxic products of bacterium enteritidis and of related micro-organisms. by sara elizabeth branham. journal of infectious diseases 1925.filtrates of fluid cultures of bact. enteritidis usually are toxic for rabbits and mice, but not guinea-pigs, when injected intravenously, but are apparently harmless when given by other routes. the time between the introduction of the poisonous fluids into the blood stream and symptoms of intoxication seems to bear no relation to the size of the dose, but is constantly about 40 to 45 minutes, whether the amount given be lethal or sublethal. the symptoms are restlessness, dyspnea, prostration, o ...19846382556
alterations in hepatic na+-k+ transport during endotoxemia in rats.the effects of endotoxemia on overall na+ and k+ transport in liver cells were studied. rats were injected with salmonella enteritidis endotoxin (5 or 10 mg/kg iv), and their blood samples and livers were obtained 4.5 h after injections. the higher, but not the lower, dose of endotoxin induced hypoglycemia and hyperlacticacidemia, which typify the metabolic deteriorations of endotoxic shock. control (saline-injected) or endotoxemic rat liver slices (0.3 mm thick) were incubated in oxygenated kre ...19846383079
intestinal carriage of campylobacter jejuni and salmonella by chicken flocks at slaughter.campylobacter jejuni were isolated in large numbers from the majority of birds sampled in colonic swabs from 28 of 60 flocks at slaughter. by contrast only small numbers of birds from 11 of the same 60 flocks yielded salmonella enteritidis serotypes. three c. jejuni isolates from each flock were serotyped on the basis of their heat-stable antigens, using antisera prepared against 16 serotypes common in campylobacter diarrhea in man. the majority (72 of 83) of the chicken isolates could be seroty ...19846383579
nongonococcal pelvic abscess caused by salmonella enteritidis.a 25-year-old patient presented with salmonella enteritidis gastroenteritis and coexistent pelvic abscess caused by the same organism. after a failed trial of parenteral antibiotics, she underwent surgical therapy. s enteritidis is now documented as a specific agent in pelvic infection.19846384853
salmonella enteritidis enterocolitis: another cause of diarrhea and erythema nodosum.the causes of concurrent erythema nodosum (en) and diarrhea include inflammatory bowel disease, yersiniosis and rarely salmonella (salmonella typhosa or s. typhimurium). the first case of en caused by s. enteritidis group b enterocolitis is reported.19846386358
procoagulant activity of macrophages associated with different murine neoplasms.mononuclear phagocytes, an integral part of the lymphoreticular infiltrate of human and experimental tumors, might contribute to tumor-associated fibrin deposition through the development of procoagulant activity (pca). we have investigated pca of tumor-associated macrophages (tam) in 6 transplanted murine tumors in syngeneic hosts; peritoneal macrophages from tumor-bearing and control animals were studied also, as reference cell populations. pca was evaluated by a one-stage clotting assay immed ...19846386701
necrotizing fasciitis caused by salmonella enteritidis.a 76-yr-old man developed necrotizing fasciitis due to salmonella enteritidis 1 month after an episode of gastroenteritis due to the same microorganism. the fact that s. enteritidis was the only organism isolated despite adequate anaerobic cultures confirm the ability of salmonellae to produce severe monomicrobial soft tissue infections.19846387893
[effect of levamisole on the formation of agglutinins against salmonellosis in weaned lambs].in order to follow up the effect of levamizol on the titer of agglutinins a killed vaccine of salmonella abortus ovis; s. enteritidis, and s. typhimurium strains was used under protection of antidenaturating agents (80 per cent sac charose) and levamizol ici at the rate of 10 mg per kg body mass. experiments were carried out with a total of 20 rabbits and 36 weaned lambs, divided into groups and injected with vaccine, vaccine and levamizol simultaneously, vaccine with levamizol following on the ...19846390935
the therapeutic significance of concomitant antitumor immunity. ii. passive transfer of concomitant immunity with ly-1+2- t cells primes established tumors in t cell-deficient recipients for endotoxin-induced regression.intravenous injection of 50 micrograms bacterial endotoxin can cause complete regression of an established sa1 sarcoma, but not if the tumor ir growing in mice that are incapable of generating concomitant immunity because they have been made t cell-deficient by thymectomy and gamma-radiation (txb mice). it also was shown that endotoxin fails to cause complete regression of a tumor that is either too large or too small. only when administered on day 9 of tumor growth, at the time of peak concomit ...19846391656
plasma catecholamines in the conscious rat during endotoxicosis.blood pressure, heart rate, and plasma catecholamines were determined in conscious unanesthetized rats given intravenous saline or endotoxin (lps from s. enteritidis). rats were monitored for 6 hr and survival determined at 24 hr. blood pressure and heart rate measurements were determined using implanted arterial cannulae. the first of two protocols involved surgical implantation of cannulae 24 hr prior to the administration of endotoxin (2.0 mg/kg) or saline. significant hypotension during the ...19846391720
pathogenesis of experimental salmonellosis: inhibition of protein synthesis by cytotoxin.salmonella cytotoxin present in cell lysates inhibited protein synthesis in both vero cells and isolated rabbit intestinal epithelial cells. a time-course experiment with vero cells revealed progressive inhibition of protein synthesis beginning as early as 1 h after exposure to the salmonella cell lysate. significant loss of membrane integrity of vero cells (measured by release of [3h]uridine) did not appear before 24 h. to demonstrate inhibited protein synthesis in intestinal tissue during expe ...19846360911
effect of surgical trauma on various aspects of the immune response in rats.the effects of a standard laparotomy on different aspects of the immune response were studied in wistar r/a rats. when the antigen was administered at the time of operation, antibody synthesis against sheep red blood cells (srbc), a thymo-dependent antigen was significantly stimulated. the same phenomenon was observed when a soluble antigen extracted from srbc was injected during the surgical procedure. on the contrary, late antibody production induced by formalinized salmonella enteritidis or e ...19846365568
[colonic dilatation due to salmonella enteritidis colitis. treatment by endoscopic aspiration]. 19846365677
suppurative epididymo-orchitis due to salmonella enteritidis.a 50-year-old man developed suppurative epididymo-orchitis 3 weeks after an episode of gastroenteritis. culture of the removed testis yielded salmonella enteritidis. the importance of remembering salmonella in the differential diagnosis of epididymo-orchitis is stressed.19846366070
[human bone marrow suppressor cells]. 19846231171
indigenous microfloras and resistance to bacterial infection in mice with experimentally induced diabetes: a possible animal model for opportunistic infection.persistent diabetes was induced in male slc:ddy mice by a single intraperitoneal injection of 200 mg/kg streptozotocin (stz). in these mice, the numbers of aerobic gram-negative bacilli, staphylococci (including micrococci), and streptococci increased, while those of other bacteria were almost unchanged in both oral and caecal floras. the mice were vulnerable to oral infection of salmonella enteritidis, intranasal infection of klebsiella pneumoniae and serratia marcescens, and contact infection ...19846231977
immunoregulation by macrophages. iii. prostaglandin e suppresses lymphocyte activation but not macrophage effector function during salmonella enteritidis infection.peritoneal macrophages obtained during primary or secondary infection with salmonella enteritidis differ in the proportions of subpopulations with the capacity to secrete prostaglandin e (pge) and interleukin 1 (il1) and have bactericidal and tumoricidal activities in vitro. using indomethacin in vivo and pge in vitro we have studied the regulation of subpopulations of lymphocytes and macrophages by pge during the inflammatory reaction. indomethacin treatment promoted clearance of the salmonella ...19846327542
salmonella liver abscess: report of a case with successful computerized tomography guided percutaneous drainage and treatment. 19846368489
potent adjuvant action of lipopolysaccharides possessing the o-specific polysaccharide moieties consisting of mannans in antibody response against protein antigen.it was previously reported that klebsiella o3 lipopolysaccharide (lps) exhibits extraordinarily strong adjuvant activity in augmenting antibody response against protein antigens in mice compared with other kinds of lps, for example, lps from escherichia coli o55, o111, and o127 and salmonella enteritidis. the present study was undertaken to clarify the relationship between the strong adjuvant activity in augmenting antibody response against deaggregated bovine gammaglobulin and the chemical stru ...19852578897
protective effects of trans-13-apt, a thromboxane receptor antagonist, in endotoxemia.the effect of the thromboxane a2/prostaglandin h2 (txa2/pgh2) receptor antagonist trans-7[2-(p-hydroxyphenethylamino)-cyclopentyl]-heptanoic acid (trans-13-apt) on certain pathogenic sequelae of endotoxic shock and associated changes in arachidonic acid metabolism in the rat was investigated. trans-13-apt, an analog of 13-azaprostanoic acid, was synthesized and found to block human platelet aggregation induced by the thromboxane mimetic u46619. pretreatment with trans-13-apt did not significantl ...19852580129
possible relationship of a 36-megadalton salmonella enteritidis plasmid to virulence in mice.all of the salmonella enteritidis strains isolated from diseased animals (61 strains) and from beef (2 strains) in japan and in west germany (1 strain), except for 2 strains isolated from ducks, harbored either a 36-megadalton (md) plasmid alone or in combination with several other plasmids of different sizes. it is likely that these 36-md plasmids from various s. enteritidis strains were derived from the same origin because their plasmid dnas showed the same cleavage patterns obtained with ecor ...19852982740
[a 68 year-old woman with cardiac insufficiency, muscular weakness and lumbar pain]. 19852987629
protective effect of a selective leukotriene antagonist in endotoxemia in the rat.the role of lipoxygenase metabolites as inflammatory mediators in endotoxic shock remains uncertain. in the present study, the effects of a selective leukotriene (lt) d4/lte4 antagonist, ly171883, 1-[2-hydroxy-3-propyl-4-[4-(1h-tetrazol-5-yl)-butoxy]-phenyl ethanone], on endotoxin-induced sequelae in the rat were assessed. ly171883 was given as a bolus (30 mg/kg i.v.) 10 min before salmonella enteritidis endotoxin (40 mg/kg) in ketamine-anesthetized (200 mg/kg i.m.) rats, followed by an infusion ...19852997435
interaction of schistosoma japonicum with salmonellae and other gram-negative bacteria.the in vitro and in vivo interaction of schistosoma japonicum with salmonellae and other gram-negative bacteria was studied. in vitro, s. japonicum associated with salmonellae and other gram-negative bacteria, and more male than female schistosomes associated with the bacteria. by using the various strains and mutants of salmonellae, we showed that salmonella typhimurium had a higher degree of association than did salmonella enteritidis and that the piliated strains of s. typhimurium associated ...19852864378
gut-derived endotoxin elicits hepatotrophic factor secretion for liver regeneration.the influence of exogenous endotoxin pretreatment on liver regeneration after partial hepatectomy was evaluated. partial hepatectomy was performed by 67% liver resection of ether-anesthetized rats with midline laparotomy and liver manipulation as the sham control. animals were pretreated with endotoxin at a dose of 33 micrograms/100 g sc or iv 24 h before surgery and then fasted. liver regeneration was quantified after partial hepatectomy by [3h]thymidine incorporation into hepatic dna, and plas ...19852865902
[differences in the production of temperate bacteriophages in lysogenic strains of salmonella enteritidis and citrobacter]. 19853160495
wall geckos (geckonidae) as reservoirs of salmonellae in nigeria: problems for epidemiology and public health.an investigation was carried out to establish the occurrence of salmonellae in household wall lizards (gecko gecko and hemidactylus sp.) in nsukka, nigeria. twentyseven out of 90 geckos examined yielded positive salmonella isolations, giving a carrier-rate of 30 per cent. while 2 isolates were non-typable, the other 25 strains belonged to 6 serotypes: salmonella weltevreden (8 strains), salmonella typhimurium, salmonella enteritidis, salmonella hvittingfos, salmonella saintpaul, and salmonella a ...19853833829
comparative in vitro activity of aztreonam and other antimicrobial agents against salmonella species.the in vitro activity of aztreonam, the first monobactam antibiotic, was compared with that of 17 other antimicrobial agents against 79 strains of salmonella species. the microorganisms were isolated from hospitalized patients, surface waters and seafoods during the decade 1975-1984. they included the following species: salmonella typhi 63, salmonella typhimurium 5, salmonella wien 5, salmonella heidelberg 2, salmonella arizonae 2, salmonella paratyphi b 1 and salmonella enteritidis 1. the minim ...19853836124
a prospective randomized comparison of cefotaxime vs ampicillin and chloramphenicol for bacterial meningitis in children.fifty children with bacterial meningitis were prospectively randomized to receive cefotaxime (50 mg/kg/dose every 6 hours) or ampicillin and chloramphenicol in standard doses. twenty-three patients received cefotaxime and 27 received standard therapy. bacterial isolates included: haemophilus influenzae (29), streptococcus pneumoniae (eight), neisseria meningitidis (eight), group b streptococci (three), and salmonella enteritidis (two). ten (34%) of the h. influenzae isolates were resistant to am ...19853847486
amelioration of the adverse effect of a gastrointestinal challenge with salmonella enteritidis on weanling rats by a yogurt diet.the response of yogurt-fed rats and the corresponding unfermented milk-fed rats to an infectious gastrointestinal challenge has been compared. after 1 (2 trials), 7 (4 trials), 14 and 21 (1 trial each) days on freeze-dried milk or yogurt diets, the rats were inoculated intra-gastrically by intubation per os with 4.5 x 10(10) +/- 0.7 colony forming units (mean +/- sem) of salmonella enteritidis. challenged and control rats were monitored during the 3 weeks post-inoculation for viability, weight g ...19853881008
salmonella bacteremia in systemic lupus erythematosus. eight-year experience at a municipal hospital.non-endemic salmonella bacteremia tends to occur in patients with chronic disease. we reviewed all cases of salmonella infection documented in adults at bellevue hospital during the years 1975-1982. unexpectedly, the most frequent underlying disease found among bacteremic patients was systemic lupus erythematosus (sle). patients with sle accounted for 6 of 30 salmonella bacteremias as compared with 13 of 2,388 non-salmonella gram-negative bacteremias. salmonella was the single most frequent gram ...19853881103
in vivo effects of bacterial lipopolysaccharide on proliferation of macrophage colony-forming cells in bone marrow and peripheral lymphoid tissues.changes in the number of macrophage colony-forming cells in various tissues of mice injected with lipopolysaccharide (lps) from klebsiella pneumoniae, escherichia coli, or salmonella enteritidis were studied. the injection of lps increased macrophage colony-forming cells in peripheral lymphoid tissues such as the spleen, mesenteric lymph nodes, and regional lymph node, although the same treatment caused the decrease of such cells in the bone marrow. this phenomenon was consistently observed when ...19853881351
alpha-aminoisobutyric acid transport in rat soleus muscle during endotoxic shock.we studied alpha-aminoisobutyric acid (aib) transport by skeletal muscle and the effect of insulin and na+ on the transport process during endotoxic shock. rats (140-160 g) were injected with salmonella enteritidis endotoxin (20 mg/kg iv) or saline and killed 5 h later. at that time an elevation of blood lactate and hypoglycemia marked the onset of shock in rats given endotoxin. aib uptake was measured in isolated soleus muscles in vitro. total cellular aib uptake in the endotoxic muscles was 25 ...19853881997
passage of salmonella enteritidis and salmonella thompson through chick ileocecal mucosa.the passage of salmonella enteritidis and s. thompson across the cecal mucosa has been visualized in an electron microscope study with the freshly hatched chick as a model. the uptake of salmonellae by macrophages took place in the cecal lumen; the macrophages became abnormal and often ruptured to release organisms back into the lumen. the entry of bacteria into the epithelial cells was associated with a series of pathological changes, beginning with the appearance of active golgi apparatus and ...19853882568
determination of the presence of root-bound endotoxin using the local shwartzman phenomenon (lsp).the purpose of these studies was to determine, by attempting to elicit the local shwartzman phenomenon (lsp), if the material extracted from periodontally involved root surfaces is actually endotoxin or only an endotoxin-like substance. a total of 719 periodontally involved teeth and 201 unerupted third molars yielded pooled samples of root surface grindings which were treated with the endotoxin extraction technique nonpyrogenic saline or pyrogen-free water. in the first study each of the recons ...19853882934
[lung abscess and empyema as clinical manifestations of salmonella infection]. 19853884926
salmonella infections in patients with acquired immunodeficiency syndrome.salmonella infections occurred in six patients with acquired immunodeficiency syndrome (aids) and one patient with probable aids. the immune system defects increase the susceptibility of patients with aids to salmonella infections. recognition of salmonellosis in patients with aids is important because of a high propensity of this organism to invade the bloodstreams of these patients, and because, unlike other infections in patients with aids, this infection can be easily treated.19853885890
an outbreak of antibiotic-resistant salmonella enteritidis in liberia, west africa.between october 1980 and august 1982, 100 patients in the pediatric population at curran lutheran hospital, zorzor, liberia were identified as having multiple drug-resistant salmonella enteritidis serotype enteritidis. the illness usually presented as an enteric fever but also as meningitis, gastroenteritis, empyema, subcutaneous abscesses, chronic otitis media, or a combination of these conditions. predisposing factors were young age and debilitation from malnutrition or measles. the mortality ...19853886805
a rare presentation of systemic salmonellosis.we are reporting an unusual case of disseminated salmonella enteritidis d, phage group e2 infection in an 18-year-old male, which was resistant to massive antibiotic treatment. rare complications such as pylephlebitis, mediastinal adenopathy, osteomyelitis with pathological clavicular fracture, osteitis and spondylitis were observed. we found an immunological defect that no doubt contributed to this severe illness.19853888847
salmonella enteritidis bacteremia in childhood.we have reviewed the clinical course of 32 children with salmonella enteritidis bacteremia and compared them with 135 children with acute gastroenteritis caused by s. enteritidis at wyler children's hospital over 4.5 years. analysis of symptoms of infection, the initial laboratory evaluation, the initial impression of the severity of illness, the clinical course, and the eventual outcome showed no differences between children with bacteremia and those with acute gastroenteritis, nor did a compar ...19853891884
[a hospital epidemic of salmonella enteritidis with more than 170 cases]. 19853892798
[respiratory distress syndrome of the adult and septicemia caused by salmonella enteritidis]. 19853894824
aortic valve endocarditis due to salmonella enteritidis.we have reported the fifth case of endocarditis due to salmonella enteritidis and the first known survivor of native aortic valve endocarditis from this pathogen. despite appropriate antibiotic therapy, aortic valve replacement was necessary because of heart failure and embolism. the patient also had concurrent viral hepatitis b infection.19853895451
double immunofluorescence microscopic technique for accurate differentiation of extracellularly and intracellularly located bacteria in cell culture.a double immunofluorescence staining technique is described for differentiation between cell-attached (extracellular) and ingested (intracellular) bacteria by hep-2 cells in cell culture monolayers. this method is based upon the observation that membranes of viable mammalian cells are impermeable for antibodies but are rendered permeable by treatment with fixatives. consequently, extracellular bacteria can be stained by specific rhodamine-labeled antibodies before fixation, and intracellular bac ...19853897263
[acute alithiasic cholecystitis caused by infectious gastroenteritis]. 19853897740
salmonella enteritidis infection in renal transplant recipients. 19853897884
treatment of experimental salmonellosis in mice with streptomycin entrapped in liposomes.liposome-entrapped streptomycin (sm) was compared with free sm for therapeutic efficacy against experimental salmonellosis in mice. all of the mice infected with the virulent strain of salmonella enteritidis 116-54 died between days 5 and 7, and a dose of 20 mg of free sm per kg administered 24 h after the bacterial inoculation did not prolong the survival. in contrast, the same dose of sm entrapped in liposomes prolonged paralleled the dose in the liposomes, and a dose as low as 1.2 mg of sm pe ...19853899004
empyema, subphrenic abscess and pyaemic splenic necrosis. a rare complication of salmonella enteritidis infection. 19853900372
plasmid-cured salmonella enteritidis al1192 as a candidate for a live vaccine.we report the immunizing capacity of salmonella enteritidis al1192, a strain that has been cured of a 36-megadalton plasmid, to protect ddy mice against subsequent challenge with virulent salmonellas. this strain, which was given subcutaneously at a dose of 10(6) organisms, provided significant protection against oral, subcutaneous, or intraperitoneal challenge by virulent wild-type strains of not only s. enteritidis, but also s. dublin, s. naestved, and s. typhimurium.19853902650
[genetic control of the immune response to salmonella enteritidis antigen]. 19853903246
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