Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| pathogenesis of congenital herpesvirus infection. case report including a description of the placenta. | 1974 | 4814890 | |
| herpesvirus strigis, a new avian herpesvirus. ii. biochemical and biophysical properties. | 1974 | 4859350 | |
| credé prophylaxis and neonatal corneal infection with herpesvirus: a model. | 1974 | 4856624 | |
| cervical cancer in yugoslavia. i. antibodies to genital herpesvirus in cases and controls. | 1974 | 4816000 | |
| studies of tumor-specific and herpesvirus nonvirion antigens. | 1974 | 4842911 | |
| the comparative influence of passive (maternal) antibodies in early exposure to jm virus of progeny chicks of dams vaccinated with jm-v leukosis strain and herpesvirus of turkey (hvt). | 1974 | 4854686 | |
| the in vitro and in vivo effect of chemotherapeutic agents on the marek's disease herpesvirus of chickens. | 1974 | 4854877 | |
| use of japanese quail embryo fibroblast cells for propagation and assay of turkey herpesvirus fc-126. | japanese quail (coturnix coturnix japonica) fibroblast cell culture monolayers were found to provide a very satisfactory system in which to propagate and assay turkey herpesvirus fc-126, which is used for production of marek's disease vaccine. japanese quail cells were more sensitive than duck cells and of approximately equal sensitivity to chicken cells. foci of infection developed rapidly and uniformly, were of larger size, and were more easily discernible in quail cells than in chicken cells. | 1974 | 4855648 |
| fulminant herpesvirus hominis hepatitis during pregnancy. | 1974 | 4855691 | |
| biogenesis of marek's disease (type ii leukosis) virus in vitro: electron microscopy and immunological study. | the kinetic events involved in marek's disease herpesvirus infection of avian cell culture were investigated by assaying viral infectivity and antigenicity as well as by electron microscopy during the infectious cycle. the levels of viral infectivity and complement-fixing (cf) antigens revealed that the rates of appearance of infectious particles and cf antigens were not synchronous. viral specific cf antigen could be detected 5 h after infection, whereas viral infectivity or the appearance of v ... | 1974 | 4856684 |
| dna configuration in the core of marek's disease virus. | marek's disease virus dna appears to be wound around a central structure connecting the two inner poles of the capsid. based on electron micrographs of marek's disease virions, a diagram of spatial configuration of virus dna is presented. this diagram may explain the pleomorphic character of the herpesvirus core observed with the electron microscope. | 1974 | 4856840 |
| properties of canine herpesvirus dna. | 1974 | 4857112 | |
| frog kidney tumors induced by herpesvirus cultured in pronephric cells. | 1974 | 4544551 | |
| electron microscopic autoradiography in the development of herpesvirus of turkey. | 1974 | 4441257 | |
| identification and characterization of a second feline herpesvirus. | a feline virus isolate previously reported as adenovirus-like has more recently been identified and characterized as a new feline herpesvirus. this herpesvirus, which appears to be cell associated, has some characteristics of the cytomegaloviruses and has been found to induce chemical crystal formations in infected cell cultures. | 1974 | 4593345 |
| [effect of homologous maternal antibodies on the vaccination with herpesvirus of turkeys (hvt)]. | 1974 | 4598094 | |
| the causative role of herpesvirus type 2 in cervical cancer. | 1974 | 4607697 | |
| antibodies to herpesvirus type 2 in breast cancer and cervical cancer patients. | 1974 | 4810088 | |
| primary herpesvirus hominis infection masquerading as scarlet fever. | 1974 | 4810739 | |
| [morphologic changes in chickens with marek's disease vaccinated with cell-associated turkey herpesvirus]. | 1974 | 4828793 | |
| early functions of the genome of herpesvirus. 3. inhibition of the transcription of the viral genome in cells treated with cycloheximide early during the infective process. | 1974 | 4833542 | |
| early functions of the genome of herpesvirus. iv. fate and translation of immediate-early viral rna. | 1974 | 4833543 | |
| ultrastructure of hamster kidney cell culture infected with herpesvirus. | hamster kidney cell culture was found susceptible to infection and replication of herpesvirus of turkey (hvt) as evidenced by cytopathic effect, induction of hvt-specific, complement-fixing antigen, and demonstration of virus particles by electron microscopy. viral structures at different developmental stages were observed. several infected cells showed a lamellar inclusion body possibly continuous with the endoplasmic reticulum. the function of these lamellar bodies is not known. | 1974 | 4842129 |
| herpesvirus type 2-induced thymidine kinase and carcinoma of the cervix. | 1974 | 4855749 | |
| transient infectivity and heterokaryon formation in hamster cell cultures inoculated with cell-associated stocks of marek's disease virus and herpesvirus of turkeys. | 1974 | 4612166 | |
| neutralization, immunofluorescence and complement fixation tests in identification of antibody to a herpesvirus type 2-induced, tumor-specific antigen in sera from squamous cervical carcinoma. | 1974 | 4612606 | |
| absence of iga antibody to herpesvirus in cervicovaginal secretions of patients with carcinoma of the cervix. | 1974 | 4615850 | |
| vaccination of chickens against marek's disease with cell-free herpesvirus of turkeys vaccine. | 1974 | 4429246 | |
| host defense mechanisms against infectious bovine rhinotracheitis virus: in vitro stimulation of sensitized lymphocytes by virus antigen. | isolated peripheral blood lymphocytes (pbl) from cattle immunized or infected with infectious bovine rhinotracheitis (ibr) virus were cultured in vitro with ultraviolet light-inactivated ibr virus, and the degree of lymphocyte blastogenesis was quantitated by measurement of the uptake of [(3)h]thymidine into acid-insoluble material. lymphocyte blastogenesis only occurred with pbl from immunized or infected animals. the optimal conditions for lymphocyte blastogenesis were defined. blastogenesis w ... | 1974 | 4426702 |
| characerization of a herpesvirus isolated from spontaneously degenerated bovine kidney cell culture. | 1974 | 4456991 | |
| [electron microscopic study of the genesis, fine structure and relationship between virus and host cell of a turkey herpesvirus in cell culture]. | 1974 | 4460929 | |
| quantitative assay of turkey herpesvirus in vaccines against marek's disease of chickens. | 1974 | 4462110 | |
| vaccination against marek's disease with the turkey herpesvirus vaccine. | 1974 | 4462113 | |
| thymoma with systemic lupus erythematosus, red blood cell aplasia, and herpesvirus infection. | 1974 | 4371386 | |
| antigenic differences between isolates of herpesvirus type 2. | 1974 | 4474145 | |
| [aminotransferase and aldolase activity in herpesvirus infections]. | 1974 | 4475519 | |
| [herpesvirus (hsv) type i and type ii - from the virological viewpoint]. | 1974 | 4478246 | |
| genital herpesvirus infection in pregnancy. | 1974 | 4368743 | |
| neo-natal mortality of puppies in queensland caused by canine herpesvirus infection. | 1974 | 4368950 | |
| neural-tube defects and herpesvirus type 2--test of a hypothesis. | 1974 | 4368952 | |
| chemotherapy of herpesvirus eye diseases. | 1974 | 4466539 | |
| marek's disease herpesvirus-induced dna polymerase. | infection of duck embryo fibroblasts by marek's disease herpesvirus (mdhv), strain ga, led to the induction of a novel dna polymerase. this novel dna polymerase, designated mdhv-induced dna polymerase, could be distinguished from the dna polymerase activities of uninfected duck embryo fibroblasts by its chromatographic behavior on phosphocellulose, by its sedimentation coefficient, and by its catalytic properties. the characteristics of mdhv-induced dna polymerase which had been purified by phos ... | 1974 | 4473569 |
| neutralizing antibodies to herpesvirus types 1 and 2 in carcinoma of the cervix, carcinoma in situ and cervical dysplasia. | 1974 | 4368955 | |
| [studies on herpesvirus of turkeys. i. isolation of herpesvirus from turkeys and its virological characteristics (author's transl)]. | 1974 | 4474560 | |
| neutralizing antibodies to herpesvirus types 1 and 2 in montreal women. | 1974 | 4368956 | |
| rapid diagnosis and typind of herpesvirus hominis by the fluorescent antibody method. | 1974 | 4369110 | |
| herpesvirus encephalitis and pulmonary sarcoidosis. a case report with necropsy findings. | 1974 | 4370996 | |
| herpesvirus (strain 0430) lesions in cercopithecus aethiops. | 1974 | 4375197 | |
| herpesvirus saimiri: vii. induction of malignant lymphoma in new zealand white rabbits. | 1974 | 4530878 | |
| a procedure for the isolation of herpesvirus saimiri lymphocyte-associated viruses and blood parasites from monkeys living in the wild. | 1974 | 4375198 | |
| fluorescent antibody study of a new bovine herpesvirus (strain dn-599). | 1974 | 4371526 | |
| recurrent cutaneous herpes simplex in hairless mice. | passively immunized hairless mice were inoculated cutaneously with herpes simplex virus. thirty-nine days later, when the primary cutaneous lesions had completely healed, the mice were treated subcutaneously with prednisone. within 12 to 30 days after starting prednisone treatment, herpesvirus was recovered by skin swabs from 12 of 71 (17%) of the treated mice. this new model has potential application for understanding and treating recurrent cutaneous herpes infections. | 1974 | 4372171 |
| the presence of the lucké herpesvirus genome in induced tadpole tumors and its oncogenicity: koch-henle postulates fulfilled. | herpesvirus extracted from a naturally occurring frog renal carcinoma (lucké tumor) induced virus-free lucké tumors in developing frogs. herpesvirus recovered from an induced tumor after incubation at low temperature of tumor fragments cultured in vitro was oncogenic when injected into developing frog embryos. with the exception of the "pure culture" requirement, this experiment fulfills koch-henle postulates for the identification of the causative agent of the lucké tumor. | 1974 | 4545010 |
| equine herpesvirus 1: biological and biophysical comparison of two viruses from different clinical entities. | 1974 | 4376548 | |
| a serologic survey in cattle to bovid herpesvirus 2. | 1974 | 4377111 | |
| lead aggravates viral disease and represses the antiviral activity of interferon inducers. | lead acetate was administered continuously in the drinking water to cd-1 male mice beginning at 4 weeks of age. an ld(10-20) of the lytic viruses or 300 plaque-forming units of rlv was inoculated intrapertioneally at 6 weeks of age. lead increased the response of the mice to all classes of viruses against which it was tested: an rna picornavirus-encephalomyocarditis (emcv), a dna herpesvirus-pseudoribies, an rna leukemia-virus-rauscher leukemia (rlv), an rna arbovirus b-st. louis encephalitis, a ... | 1974 | 4364644 |
| anti-herpesvirus action of isoprinosine. | anti-herpesvirus effects of isoprinosine were found to be condition-dependent in vitro and in vivo. a herpes type 1 strain, grown in primary rabbit kidney cells, was not susceptible to isoprinosine when cytopathic effect was evaluated, but was modestly inhibited when plaque-forming methocel overlay was used in the same cell line. however, the growth of a herpes type 2 strain was inhibited by isoprinosine in this system when cytopathic effect was evaluated. both viruses produced an encephalitis i ... | 1974 | 4365114 |
| regulation of herpesvirus macromolecular synthesis. i. cascade regulation of the synthesis of three groups of viral proteins. | based on evidence that 50% of herpes simplex 1 dna is transcribed in hep-2 cells in the absence of protein synthesis we examined the order and rates of synthesis of viral polypeptides in infected cells after reversal of cycloheximide- or puromycin-mediated inhibition of protein synthesis. these experiments showed that viral polypeptides formed three sequentially synthesized, coordinately regulated groups designated alpha, beta, and gamma. specifically: (i) the alpha group, containing one minor s ... | 1974 | 4365321 |
| genital herpes in guinea-pigs. an experimental model with herpesvirus hominis. | 1974 | 4365940 | |
| reactivity of envelope, capsid, and soluble antigens of herpesvirus hominis types 1 and 2 in the indirect hemagglutination test. | envelope, capsid, and soluble antigens of herpesvirus hominis (hvh) types 1 and 2 were compared to crude antigens (disrupted hvh-infected cells) for potency, type-specificity, and diagnostic value in the indirect hemagglutination (iha) test. the envelope appeared to be the predominant component reacting in the iha test, but recurrent hvh infections increased the reactivity of human sera with capsid antigens. the soluble antigens reacted in the iha test with hvh immune animal sera, but very few c ... | 1974 | 4366916 |
| [epidemiology of varicella-zoster-virus and of herpesvirus hominis (author's transl)]. | 1974 | 4377569 | |
| simultaneous vaccination of day-old chickens against newcastle and marek's diseases. | commercial day-old chicks vaccinated against marek's disease (md) with turkey herpesvirus (hvt) were tested for their ability to respond to a live newcastle disease vaccine (ndv) - la sota strain - administered by different routes. simultaneous vaccination of day-old birds with hvt and ndv did not affect the immune response to ndv nor the viraemia induced by hvt vaccination. md and nd vaccinations performed together, the first by the intramuscular route and the second by beak dipping, gave a val ... | 1974 | 18777255 |
| lyophilized turkey herpesvirus (hvt): stability of vaccine and minimum protective dose. | the research reported showed that: the stability of cell-free hvt vaccine, lyophilized and sealed under vacuum, is very high: after one year at 4 degrees -6 degrees c and after 10 days at 37 degrees c the titre decreased only about 0.4 log(10)', the stability of the vaccine, when reconstituted for use in the diluent (sucrose-phosphate buffer), is high (80%) for at least 2 hours; the degree of protection, found in 3 tests, was about 90% with an inoculum of 20 to 100 pfu, and the pd50 was 4.9 pfu ... | 1974 | 18777253 |
| iododeoxyuridine and herpesviral encephalitis: lack of inhibitory action against low-grade viral replication. | equine herpesvirus 1 replicated in the brains of 2-week-old mice but did not produce fatal encephalitis; it thus simulated the majority of cases of herpes simplex encephalitis in man. this replication was not inhibited by iododeoxyuridine, although in tissue cultures the equine and human viruses were equally susceptible. the continued use of iododeoxyuridine for human encephalitis should be seriously questioned. | 1974 | 15825425 |
| proflavine and light in the treatment of experimental herpetic ocular infections. | the effect of purified proflavine and light exposure was assessed in rabbits whose eyes had been infected with one of two strains of herpesvirus. in comparing proflavine-light and placebo-light treatment, 0.1% proflavine administered twice daily for 5 days had a significant effect in suppressing herpetic eye disease, but 0.05% proflavine was less effective. in addition to being effective in infections with either virus strain, the 0.1% proflavine also suppressed intensity of corneal epithelial u ... | 1974 | 15825315 |
| inactivation of herpes simplex virus by thiosemicarbazones and certain cations. | we demonstrated that herpes simplex virus types 1 and 2, including a type 2 strain which transforms hamster cells in vitro, and herpesvirus saimiri are inactivated by exposure to thiosemicarbazones. because thiosemicarbazones are thought to interact with heavy metals in this inactivation process (9), we tested and found some of these herpesviruses to be susceptible to exposure to certain heavy metals. a virion polymerase was sought because the ribonucleic acid (rna)-dependent deoxyribonucleic ac ... | 1974 | 15825395 |
| variables influencing the in vitro susceptibilities of herpes simplex viruses to antiviral drugs. | some of the variables in a microtiter tissue culture method for estimating antiviral susceptibility of herpes simplex viruses (hsv) were studied. six antiviral drugs (5-iodo-2'-deoxyuridine, cytosine arabinoside, 9-beta-arabinofuranosyladenine, isoprinosine, virazole, and 2-deoxy-d-glucose) and three tissue culture cell lines (primary rabbit kidney, wi-38, and rat brain) were studied. four different inocula (10, 100, 1,000, and 2,000 mean tissue culture doses) and nine isolates of hsv were teste ... | 1974 | 15828168 |
| determination of plaque inhibitory activity of adenine arabinoside (9-beta-d-arabinofuranosyladenine) for herpesviruses using an adenosine deaminase inhibitor. | the in vitro susceptibility of type 1 and type 2 strains of herpesvirus hominis to 9-beta-d-arabinofuranosyladenine (adenine arabinoside, ara-a) was measured in a system where deamination was inhibited. under these conditions, it was possible to measure the activity of low concentrations of ara-a. it was determined that plaque inhibitory concentration for type 1 viruses was less than 3 mug/ml for all strains tested. the plaque inhibitory concentration for 7 of 10 type 2 strains was also less tha ... | 1974 | 15828177 |
| editorial: vaccination against an oncogenic herpesvirus. | 1975 | 46967 | |
| hazards from simian herpes viruses: reactivation of skin lesions with virus shedding. | a new simian herpes virus with biological properties similar to herpes simplex and to simian "b" virus has been used as a model system for studying virus latency in dorsal root spinal sensory ganglia. following intradermal injection, virus is present in the skin lesions and corresponding ganglia only, during the acute stage of the disease. by organ-culture techniques, latent virus was rescued from ganglia up to 2 years later. no latent virus was ever found in skin organ cultures of the primar ... | 1975 | 47078 |
| characterization of a caprine herpesvirus. | a virus, which was isolated from kids (capra hircus) affected with a relatively severe generalized infection, was found to contain dna and to have a buoyant density of 1.2820 g/cm3. the virus was sensitive to the action of lipid solvents and trypsin and was rapidly inactivated at ph 3.0 and at temperatures of 50 and 56 c. the virion, an icosahedron consisting of a nucleoid surrounded by a double membrane, measured approximately 135 nm in diameter. on the basis of its chemical and physical proper ... | 1975 | 933 |
| metabolic characteristics of cells infected with a herpesvirus of turkeys. | chicken embryo fibroblasts infected with the nononcogenic herpesvirus of turkeys (hvt) displayed an increased rate of glucose uptake, a pronounced alteration of the ph of the medium, and an increased production of lactic acid when compared to mock-infected cultures. objective estimates of cytopathology (quantifiable neutral red uptake and cell protein determination) showed that cell deterioration was a slow process in hvt-infected cells when compared to infection by herpes simplex virus. experim ... | 1975 | 1548 |
| defense mechanisms against bovine herpesvirus: relationship of virus-host cell events to susceptibility to antibody-complement cell lysis. | the interaction of infectious bovine rhinotracheitis virus and susceptible host cells was examined to determine whether an infected cell could be destroyed by humoral immune mechanisms before or after the transmission of virus to susceptible adjacent cells. viral antigens were detectable on cell membranes at 6 h postinfection, but cells were not susceptible to antibody-complement lysis until 10 h postinfection. intracellular infectious virus was also detectable at 10 h postinfection, and transmi ... | 1975 | 53206 |
| mode of inhibition of herpes simplex virus dna polymerase by phosphonoacetate. | phosphonoacetate is a highly specific inhibitor of herpes simplex virus-induced dna polymerase. sensitivity of herpesvirus type 1 or type 2 induced dna polymerase to the drug was similar. however, dna polymerases from other sources such as the host cells (wi-38), micrococcus luteus, and hepatitis b virus were highly resistant. in addition, escherichia coli rna polymerase and reverse transcriptase of rous sarcoma virus were also insensitive to the drug. enzyme kinetic studies showed that inhibiti ... | 1975 | 53071 |
| letter: herpesvirus infection and cancer. | 1975 | 49591 | |
| no evidence for particles encapsulating rna-instructed dna polymerase and high molecular weight virus-related rna in herpesvirus induced tumours of non-human primates. | the simultaneous detection test gave no evidence for the presence of rna tumour viruses in herpesvirus induced malignant lymphomas of non-human primates. the 12 tumours tested were obtained from three different monkey species inoculated with herpesvirus saimiri or herpesvirus ateles. particles encapsulating rna-instructed dna polymerase and high mol. wt. virus-related rna were easily demonstrated in tumours of the mouse induced by type-c or type-b oncornaviruses and in human lymphoid cells infec ... | 1975 | 49397 |
| chronic antigenic stimulation, herpesvirus infection, and cancer in transplant recipients. | an increased incidence of malignancy has been reported in transplant recipients. the pathogenesis of this increase was originally attributed to immunosuppressive therapy. however, not all tumours are increased in proportion to their occurrence in the general population-75% of reported tumours are lymphorproliferative or carcinoma of the skin, lip, or cervix. this cannot be explained by impaired immunosurveillance, and alternative hypotheses must be considered. 90% of transplant recipients develo ... | 1975 | 48901 |
| characterization of a new serotype of marek's disease herpesvirus. | the hprs-24 strain of marek's disease herpesvirus was selected for closer study from a group of virus isolates that appeared apathogenic under standard test conditons. protection studies revealed an immunological relationship between this virus strain and acute marek's disease herpesvirus. in chicken kidney cell cultures, the hprs-24 strain caused small and slowly developing plaques, and the proportion of infected cells was less than with other strains. in chicken embryo fibroblast cultures, thi ... | 1975 | 66180 |
| t-lymphoblastoid cell lines from marek's disease lymphomas. | the establishment and continuous culture of two lymphoblastoid cell lines derived from marek's disease lymphomas is described. although the cells carried t-lymphocyte surface antigens, they had many features in common with cultured burkitt's lymphoma lymphoblasts, which carry b-cell determinants. a small proportion acted as infectious units in tissue culture, and a similarly small proportion contained intranuclear immature herpesvirus particles. the cells did not respond to phytohaemagglutinin. ... | 1975 | 66182 |
| synthesis of proteins in cells infected with herpesvirus. x. proteins excreted by cells infected with herpes simplex virus, types 1 and 2. | 1975 | 163536 | |
| lysis of herpesvirus-infected cells by immune spleen cells. | spleen cells from herpes simplex-infected mice have been shown to lyse 51cr-labeled virus-infected target cells. the cell-mediated lysis was shown to be antibody dependent but not involving adherent cells. lysis of infected cells by this mechanism may be one form of host defense in infection by some viruses. | 1975 | 164406 |
| pathogenic and serologic studies of japanese quail infected with jm strain of marek's disease herpesvirus. | japanese quail were inoculated with marek's disease herpesvirus at 1 day of age, and a second group of the same age was infected by contact with inoculated quail. a third group raised in our laboratory as a source of hatching eggs was accidentally infected with marek's disease (md). all quail were observed and examined for periods up to 360 days; the usual clinical signs of md were not observed. however, the birds were susceptible to md infection because of the evidence that: 1) the md-specific ... | 1975 | 164560 |
| depression in lymphocyte response to general mitogens by owl monkeys infected with herpesvirus saimiri. | the effect of herpesvirus saimiri (hvs) infection on the response of owl monkey lymphocytes to general mitogens was examined during the development of neoplastic disease. the reactivity of the lymphocytes was then correlated with the clinical condition of the infected monkeys and the content of virus rescued from the peripheral blood lymphocytes (pbl). eight monkeys developed lymphoma which, in six monkeys, was accompanied by lymphocytic leukemia. all animals that died of hvs-induced neoplasia c ... | 1975 | 164565 |
| effect of bacillus calmette-guérin immunization in marmosets infected experimentally with herpesvirus saimiri. | eight white-lipped marmosets immunized with bcg and 3 sham-immunized marmosets were studied after inoculation with herpesvirus saimiri (hvs). bcg immunization had no significant influence on the incidence of infection by hvs, incidence of fatal malignant lymphoma, time of leukemia onset, development or titer of hvs antibodies, or average survival time. one bcg-immunized, hvs-infected marmoset failed to develop malignant lymphoma, whereas the remaining 10 hvs-infected marmosets died of malignant ... | 1975 | 164566 |
| cell-mediated immunity to herpes simplex in humans: lymphocyte cytotoxicity measured by 51-cr release from infected cells. | we assessed cell-mediated immunity to herpes simplex virus type 1 antigen in patients suffering from recurrent cold sores and in a series of healthy controls. paradoxically, all those subject to recurrent herpetic infections had, without exception, evidence of cell-mediated immunity to herpes antigens. this was demonstrated by lymphocyte transformation and specific 51cr release from infected human amnion cells after incubation with peripheal blood mononuclear cells. where performed, skin tests w ... | 1975 | 163220 |
| in vitro transformation of hamster cells by herpes simplex virus type 2 from human prostatic cancer cells. | a cell-associated herpes simplex virus type 2 found in a human prostatic carcinoma induced in vitro transformation of hamster embryo cells. the transformed cells (yw-74) have been shown to be hamster cells by karyotype analysis. their epithelial morphology and growth pattern, which are different from the parental cell, have remained stable through cell passages. the presence of herpesvirus antigens in the transformed cells was determined by specific immunofluorescence and colony inhibition tests ... | 1975 | 165889 |
| inclusion body disease (herpesvirus infection) of falcons (ibdf). | inclusion body disease of falcons (ibdf) is caused by a herpesvirus. the clinical course is short, 24 to 72 hours in duration, and is characterized by mild to severe depression and weakness often accompanied by anorexia. the disease is invariably fatal. the virus has a marked affinity for the reticuloendothelial system and hepatocytes,producing focal to diffuse necrosis of infected tissues accompanied by the formation of intranuclear inclusion bodies. the virus is pathogenic for american kestrel ... | 1975 | 163383 |
| defense mechanisms against infectious bovine rhinotracheitis virus: inhibition of virus infection by murine macrophages. | an in vitro method is described to measure the inhibitory activity of murine peritoneal exudate cells against viral plaque formation by a bovine herpes-virus-infectious bovin'e rhinotracheitis virus. microtiter plates containing 96 bovine kidney cell monolayers were infected with a range of virus concentration and peritoneal exudate cells were subsequently added. when a sufficient number of cells was added, viral plaques were not detectable and free infectious virus did not occur in the culture ... | 1975 | 163796 |
| psittacine herpesvirus infection resembling pacheco's parrot disease. | herpesvirus was detected by electron microscopy in hepatocytes of psittacine birds that died at a florida aviary. the virus was identified in hepatocytes of chick embryos and budgerigars that were given injections of liver suspensions from naturally infected psittacines. infected hepatocytes had prominent intranuclear inclusions that contained naked nucleocapsids. both naked and enveloped virions were seen in the cytoplasm of hepatocytes, and enveloped nucleocapsids occasionally were seen in the ... | 1975 | 163868 |
| isolation of equine herpesvirus type 1 from a horse with an acute paralytic disease. | a standardbred mare became paralyzed shortly after showing signs of an upper respiratory infection. the mare was euthanized and equine herpesvirus type 1 was isolated from the brain and spinal cord. | 1975 | 166741 |
| properties of a chicken lymphoblastoid cell line from marek's disease tumor. | properties of a chicken lymphoblastoid cell line (msb-1) from a marek's disease tumor were studied. the cell line grew well at 41 degrees c in medium rpmi-1640 supplemented with 10% bovine fetal serum and had a doubling time of 8-12 hours. cells grown in stationary suspension culture did not attach to the vessel and had the morphology of typical lymphoblasts. at 37 degrees c, the cell line grew initially but ceased to divide after several subcultures. in the subcultures maintained for 48-72 hour ... | 1975 | 163334 |
| effect of human leukocyte interferon on vaccinia-and herpes virus-infected cell cultures and monkey corneas. | pretreatment of human fibroblast cultures with human leukocyte interferon (hif, 1,000 iu/ml) resulted in a 24-h delay of virus replication after infection with vaccinia virus and herpes simplex virus type 1 and type 2. additional hif treatment 24 h after infection effectively lowered the maximum yield of viral infectivity. equal results were obtained in simian cells with 3,000 iu of hif per ml. the spread of two cell-bound herpesviruses, varicella zoster virus and medical lake macaque herpesviru ... | 1975 | 166924 |
| herpersvirus strigis: host spectrum and distribution in infected owls. | herpesvirus strigis, a new species of the genus herpesvirus, is a pathogen for several species of owls in the order srigiformes. natural infection has been observed in the eagle owl (bubo bubo l.), long-eared owl (asio otus l.) and snowy owl (nyctea scandiaca l.) in addition the little owl (athene noctua scopolic) and tengmalms owl (aegolius funereus l.) was experimentally infected. on the other hand the tawny owl (strix aluco l.) and barn owl (tyto albo scopoli) proved resistant to a massive ex ... | 1975 | 167204 |
| multiple herpesvirus simiae isolation from a rhesus monkey which died of cerebral infarction. | a rhesus monkey housed in the new england regional primate research center for more than 4 yr died after an illness of 19 da. clinical signs included central nervous system involvement and ulcers on the labial mucosa. microscopically, the cause of death was established as multiple cerebral infarction. lesions characteristic of herpesvirus infections were not present in the brain nor in any other tissue; however, herpesvirus simiae was isolated from oral and anal swabs as well as from tongue and ... | 1975 | 167229 |
| horizontal transmission of turkey herpesvirus to chickens. iv. viral maturation in the feather follicle epithelium. | an experimental line of white leghorns (wsu-vs) and a commerical line inoculated with turkey herpesvirus (hvt) at 1 or 8 weeks old did not differ in the occurrence of infectious cell-free hvt in their feather-tip preparations (ft-hvt). the birds examined at 2 weeks postinoculation (pi) were always positive for ft-hvt regardless of age at virus inoculation, dose of hvt inoculated, or genetic line of chickens, whereas only a few were positive at 4 weeks and none at 6 weeks pi. | 1975 | 164176 |
| spontaneous lymphoma associated with herpesvirus saimiri in owl monkeys. | two cases of lymphoma and one case of lymphoproliferative disease were found in a group of 7 owl monkeys imported into our colony as a single group. herpesvirus saimiri (hvs) was isolated from the tumor cells of 1 lymphoma by cocultivation and from kidney cell cultures from the monkey with lymphoproliferative disease. antibody to hvs was found in serum samples from 2 monkeys positive for hvs but not in the sera from the 4 clinically normal monkeys. antibody to epstein-barr virus-infected cells w ... | 1975 | 163336 |
| virus infections in renal transplant recipients. | 534 serum samples from 73 renal transplant recipients, 41 haemodialysis patients, and 99 blood and organ donors were examined serologically for antibodies against cytomegalo, h. simplex (types 1 and 2), varicella-zoster, epstein-barr, adeno, influenza, parainfluenza, respiratory syncytial, measles, picorna- and human polyoma- viruses. serum specimens were stored in the lyophilized state until examined thus enabling a simultaneous testing of all samples belonging to one patient. all antigens, com ... | 1975 | 126545 |
| the ultrastructure of disrupted herpesvirus nucleocapsids. | 1975 | 167517 | |
| invasion of the central nervous system by herpes simplex virus type 1 after subcutaneous inoculation of immunosuppressed mice. | young adult mice given subcutaneous inoculations in the rear footpad with herpes simplex virus type 1 were found to be resistant to infection unless they were immunosuppressed with sublethal doses of irradiation or cyclophosphamide. in these mice, virus multiplied in the sciatic nerve three to four days after inoculation. this development was followed by multiplication of virus in the spinal cord and brain, which caused death of the mice in about eight days. no virus was detected in the blood or ... | 1975 | 162925 |
| studies on immunity to aujeszky's disease (pseudorabies) virus infection in pigs. | aujeszky's disease is primarily a disease of pigs caused by a herpesvirus. in pigs, the primary site of virus replication is the nasopharynx. some strains cause lesions only in the central nervous system, others cause rhinitis, pneumonia and encephalitis. colostrum from immune sows protected 3 day old piglets from experimental infection, but did not prevent the piglets excreting virus. colostral antibodies were 11-16-fold greater than the serum titres in the sows and the half life of passiveanti ... | 1975 | 165131 |