Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| early colonization of dental implants by putative periodontal pathogens in partially edentulous patients. | there is limited scientific information available on the early colonization of the peri-implant pockets in partially edentulous individuals. knowledge about this process is one step in better understanding the etiology and pathogenesis of peri-implantitis. in this study, the early colonization of the peri-implant pockets by putative periodontal pathogens was studied in 20 partially edentulous individuals using anaerobic culture techniques. at baseline, the presence and levels of putative periodo ... | 2000 | 11168244 |
| diagnostic characteristics of clinical and microbiological tests for monitoring periodontal and peri-implant mucosal tissue conditions during supportive periodontal therapy (spt). | the aim of this study was to evaluate a clinical and a microbiological test for monitoring tissue condition during supportive periodontal therapy (spt) and to compare their diagnostic characteristics at implant and tooth sites. twelve female (age: 37-72 years) and 7 male patients (age: 26-83 years) were evaluated in this study on the basis of availability to follow a rigid spt program. patients had received a complete periodontal examination at 1 and 5 years after implant placement. this include ... | 2000 | 11168245 |
| prevalence of prevotella intermedia and prevotella nigrescens in infected root canals from a brazilian population. | the purpose of the present study was to evaluate the prevalence of prevotella intermedia and prevotella nigrescens in symptomatic and asymptomatic endodontic infections from a brazilian population. dna extracted from samples obtained from 28 cases of endodontic infection were examined by the 16s rdna-directed polymerase chain reaction (pcr) method. pcr detected p. intermedia in 7.1% of the cases (2 out of 28 teeth) and p. nigrescens in only one sample (3.6%). the low prevalence of p. intermedia ... | 2000 | 11359249 |
| mouthrinses: a comparative microbiological study. | this study was performed in order to evaluate the efficacy of different mouthrinses whose use is extended in spain. six different antiseptic mouthrinses were studied by means of determination of minimal inhibitory concentration (mic) values against klebsiella pneumoniae, serratia marcescens, escherichia coli, pseudomonas aeruginosa, staphylococcus aureus, salmonella typhimurium, bacillus subtilis, streptococcus mutans, prevotella intermedia, porphyromonas gingivalis and actinobacillus actinomyce ... | 2000 | 11799736 |
| prevalence of porphyromonas gingivalis. prevotella intermedia and actinobacillus actinomycetemcomítans in patients with rapidly progressive periodontitis. | 2000 | 11507550 | |
| oro-facial gangrene (noma/cancrum oris): pathogenetic mechanisms. | cancrum oris (noma) is a devastating infectious disease which destroys the soft and hard tissues of the oral and para-oral structures. the dehumanizing oro-facial gangrenous lesion affects predominantly children ages 2 to 16 years, particularly in sub-saharan africa, where the estimated frequency in some communities varies from 1 to 7 cases per 1000 population. the risk factors are poverty, malnutrition, poor oral hygiene, residential proximity to livestock in unsanitary environments, and infect ... | 2000 | 12002813 |
| [distribution of prevotella intermedia in the periodontal plaques of children and their parents]. | to investigate the distribution of prevotella intermedia (pi) among family members by culturing technique and biochemical identification. | 2000 | 12539530 |
| [study of bacteriology on local application of tinidazole stilus in treatment for periodontitis]. | the study was designed to evaluate the antiseptic efficacy of tinidazole stilus against periodontal pathogen. | 2001 | 12539636 |
| antimicrobial effectiveness of electro-chemically activated water as an endodontic irrigation solution. | the aim of this in vitro study was to evaluate the antimicrobial effectiveness of electro-chemically activated water (eca) as an endodontic irrigation solution. | 2001 | 12193270 |
| maternal periodontitis and prematurity. part ii: maternal infection and fetal exposure. | clinical data from the first 812 deliveries from a cohort study of pregnant mothers entitled oral conditions and pregnancy (ocap) demonstrate that both antepartum maternal periodontal disease and incidence/progression of periodontal disease are associated with preterm birth and growth restriction after adjusting for traditional obstetric risk factors. in the current study we present measures of maternal periodontal infection using whole chromosomal dna probes to identify 15 periodontal organisms ... | 2001 | 11887461 |
| humoral immune response in early-onset periodontitis: influence of smoking. | sixty-five patients with generalised early-onset periodontitis (g-eop) (age range 16-42 years, 32 smokers and 33 non-smokers) were assessed for antibody titres and avidity to a panel of five suspected periodontal pathogens (porphyromonas gingivalis, actinobacillus actinomycetemcomitans, prevotella intermedia, treponema denticola and bacteroides forsythus). thirty-four of these patients were untreated (17 smokers and 17 non-smokers), and thirty-one were in the maintenance phase of periodontal the ... | 2001 | 11519695 |
| nucleic acid probes in periodontal diagnosis. | periodontal disease is considered as an infection caused by a variety of microorganisms. considering the vast range of microbial species involved in the causation of periodontal diseases, a specific diagnostic procedure, to identify the various organisms involved is a major necessity. a number of diagnostic procedures, including microbiological and immunological have been utilized in the diagnosis of periodontal disease. the dna probe technology provides both a sensitive and specific assay and a ... | 2001 | 11808070 |
| [a comparative study of various evaluation methods of the antibiotic sensitivity of strict anaerobic bacteria of the subgingival flora]. | the study on the sensitiveness of slow-growing anaerobes bacteria to antibiotics is delicate when you consider the technical motives that make it difficult to transpose the standard methods frequently used in microbiological laboratories. the three main methods used to determine susceptibility to antibiotics are: disk-diffusion test, antibiotics containing microdilution plates and atb ana (biomérieux). the aim of this study is to compare the effectiveness of each of these methods on severe anaer ... | 2001 | 11808376 |
| papillon-lefèvre syndrome: serum immunoglobulin g (igg) subclass antibody response to periodontopathic bacteria. a case report. | papillon-lefevre syndrome (pls) is a rare autosomal recessive disorder which is characterized by palmar-plantar hyperkeratosis and rapid periodontal destruction of both primary and permanent dentitions. in this case report, we present clinical features, and microbiological and immunological findings of 40 month-old thai male pls patient. | 2001 | 11811512 |
| antimicrobial activity of four root canal sealers against endodontic pathogens. | the antibacterial effects of various types of widely used endodontic sealers have not been compared systematically on facultative or obligate anaerobic endodontic pathogens. the aim of this study was to evaluate the antimicrobial properties of four commonly used endodontic sealers: two epoxy-resin-based sealers (ah26, ah plus), one zinc-oxide eugenol-based sealer (n2), and one calcium hydroxide-based sealer (sealapex). the testing microbes were four facultative anaerobic species (streptococcus m ... | 2001 | 11800436 |
| on the symmetry of periodontal disease. | symmetry is a common feature of biological systems, and can be observed in multiple aspects of the human body. the purpose of this study was to estimate the impact of symmetry on variance observed in intraoral topographic distribution patterns of chronic periodontitis. | 2001 | 11442733 |
| distribution of the tetracycline resistance determinant tetq gene in oral isolates of black-pigmented anaerobes in japan. | we investigated the distribution of tetracycline resistance determinant tetq in oral black-pigmented anaerobes using a polymerase chain reaction (pcr) method: a total of 185 healthy subjects were divided into 3 groups based on subject age: young (6 to 10 years, n=58), middle (11 to 40 years, n=96), and elder (exactly 70 years, n=31). the prevalence of black-pigmented anaerobes in the gingival sulcus among these groups was 29.3%, 28.2%, and 64.5%, respectively. the prevalence of prevotella nigres ... | 2001 | 11442847 |
| monocytic cell activation by nonendotoxic glycoprotein from prevotella intermedia atcc 25611 is mediated by toll-like receptor 2. | lipopolysaccharide (lps) preparations from gram-negative black-pigmented bacteria such as porphyromonas gingivalis and prevotella intermedia activate cells from non-lps-responsive c3h/hej mice, but it is still unclear whether this activity is due to the unique structure of lps or to a minor component(s) responsible for the activity in the preparation. a nonendotoxic glycoprotein with bioactivity against cells from c3h/hej mice was purified from a hot phenol-water extract of p. intermedia atcc 25 ... | 2001 | 11447173 |
| cloning and biochemical characterization of a class a beta-lactamase from prevotella intermedia. | the gene encoding a beta-lactamase of prevotella intermedia was cloned and sequenced. this gene, called cfxa2, shared 98% identity with cfxa, the structural gene of a beta-lactamase previously described in bacteroides vulgatus. the deduced protein sequence had a k272e substitution. cfxa2 had the characteristics of class a, group 2e beta-lactamases. | 2001 | 11451705 |
| microbiology of periodontal disease in children and young adults. | 2001 | 11452905 | |
| elevated mrna expression for supervillin and vascular endothelial growth factor in human neutrophils stimulated with lipopolysaccharide from porphyromonas gingivalis. | differential gene expression was examined in human neutrophils stimulated with lipopolysaccharide from porphyromonas gingivalis (p. gingivalis-lps) using rna fingerprinting by arbitrarily primed polymerase chain reaction (rap-pcr). lps from escherichia coli (e. coli-lps) was used as control. more than 200 differently expressed transcripts were found in 8 subjects showing differential regulation at the transcriptional level. densitometric analyses revealed that 42-100 genes were upregulated, whil ... | 2001 | 11453114 |
| [bacteriologic investigation of periodontal infections]. | the gingivitis and periodontitis are very common diseases in hungary: more than 80% of the adult population suffers with gingivitis and 15-20% has destructive periodontitis. the composition of peridontopathogenic bacterial flora is totally different from that of the bacterial flora causing dental infections. in periodontal infections dominantly facultative and obligatory anaerobic microorganisms occur (actinobacillus actinomycetemcomitans (a. actinomycetemcomitans), porphyromonas gingivalis (p. ... | 2001 | 11480243 |
| an in vitro evaluation of the antimicrobial efficacy of irrigants on biofilms of root canal isolates. | the bactericidal effect of four antimicrobial agents was investigated against single-species biofilms derived from a range of root canal isolates. | 2001 | 11482142 |
| regulation of interleukin-6 expression in human dental pulp cell cultures stimulated with prevotella intermedia lipopolysaccharide. | interleukin (il)-6 expression in human dental pulp cell cultures after stimulation with prevotella intermedia lipopolysaccharide (lps) was investigated by northern blot analysis, enzyme immunoassay, and bioassay. the il-6 mrna expression began to increase after 1 hr and continued after up to 8 hr of exposure on stimulation with 10 microg/ml of p. intermedia lps. the bioactivity was dose-dependent on the concentration of p. intermedia lps (0 to 100 microg/ml). the il-6 mrna expression was inhibit ... | 2001 | 11485266 |
| detection of putative oral pathogens in acute periradicular abscesses by 16s rdna-directed polymerase chain reaction. | a 16s rdna-directed polymerase chain reaction method was used to assess the occurrence of four black-pigmented anaerobic rods, treponema denticola, and actinobacillus actinomycetemcomitans in acute periradicular abscesses. pus was collected by aspiration from 10 cases diagnosed as acute abscesses of endodontic origin. dna was extracted from the samples and analyzed using a polymerase chain reaction-based identification assay. the method allowed detecting black-pigmented anaerobes in 80% of the e ... | 2001 | 11487143 |
| treatment of peri-implantitis by local delivery of tetracycline. clinical, microbiological and radiological results. | the purpose of this study was to investigate the clinical, microbiological and radiological effects of peri-implantitis therapy by local delivery of tetracycline. in 25 partially edentulous patients, 30 implants with radiographic evidence of circumferential bone loss, and peri-implant probing depths > or =5 mm were treated with polymeric tetracycline hcl-containing fibers. clinical and microbial parameters were recorded at baseline, and 1, 3, 6, and 12 months (m) after treatment. standardized ra ... | 2001 | 11488856 |
| clinical and microbiological evaluation of ligature-induced peri-implantitis and periodontitis in dogs. | the purpose of this study was to evaluate the attachment loss around teeth and implants by clinical and microbiological analysis. the mandibular premolars were extracted in 5 mongrel dogs and, 3 months later, two titanium implants were installed on each side of the mandible and, after another 3 months, abutment connection was performed. plaque control in the implants and maxillary premolars was maintained for two weeks prior to the start of the main experiment. on day 0 and 30 days after ligatur ... | 2001 | 11488857 |
| the clinical relevance of microbiologic testing: a comparative analysis of microbiologic samples secured from the same sites and cultured in two independent laboratories. | a field study using five different private periodontal practices was conducted; it compared two microbiologic culture samples simultaneously secured from the same sites within 23 individual patients and submitted for bacterial identification and antibiotic sensitivity testing to two separate laboratories. the results from the two laboratories were often different. in no instance did both laboratories agree on the presence of identical bacterial species. when only bacteria above threshold levels ... | 2001 | 11490400 |
| clinical periodontal findings and microflora profiles in children with chronic neutropenia under supervised oral hygiene. | this is the first known case report that used a polymerase chain reaction (pcr)-based method to help identify the oral microflora in patients with chronic neutropenia. in this study, we report clinical periodontal findings and microflora profiles of 2 children, 1 with severe congenital neutropenia (scn, kostmann type) and 1 with cyclic neutropenia (cn). | 2001 | 11495144 |
| comparative clinical and microbiological effects of subgingival metronidazole application in adult periodontitis; 12-months results. | the aim of the present study was to evaluate the clinical and microbiological effects of subgingival application of 25% metronidazole dental gel as an adjunct to scaling and root planing (srp) in the treatment of adult periodontitis. eighty teeth in 18 patients were evaluated using a split mouth design. the test teeth received srp and a 25% metronidazole gel applied subgingivally on days 0 and 7. the control teeth received srp only. clinical and microbiological examinations were carried out befo ... | 2001 | 12666946 |
| subgingival microflora and antibody responses against periodontal bacteria of young japanese patients with type 1 diabetes mellitus. | periodontal disease is a complication of patients with type 1 diabetes mellitus (t1dm), although the mechanisms responsible for this relationship remain unclear. the aim of this study was to examine oral manifestations and the prevalence of periodontal pathogens from subgingival plaque samples and serum igg antibody levels against them in young japanese type 1 diabetic subjects. one hundred and seventeen japanese t1dm subjects (53 male, 64 female, mean age +/- sd, 16 +/- 6.5 years) participated ... | 2001 | 12666949 |
| serum phenytoin concentration and igg antibody titre to periodontal bacteria in patients with phenytoin-induced gingival overgrowth. | epileptic patients taking phenytoin with gingival-overgrowth and those without gingival-overgrowth were compared for daily drug dose, plasma total phenytoin concentration, plasma free-phenytoin concentration and serum igg antibody titre against 13 periodontal bacteria. significantly higher daily drug dose was noted in patients with gingival overgrowth (p < 0.05) when compared with those without overgrowth. in addition, both total and free forms of plasma phenytoin concentration were significantl ... | 2001 | 12666977 |
| microflora in oral ecosystems in primary sjögren's syndrome. | knowledge of the effect of primary sjögren's syndrome (pss) on the microbial flora in the different predilection sites for oral disorders is needed for planning preventive treatment. we carried out microbial analysis of samples from the dorsum of the tongue, smooth mucosa, supragingival tooth surfaces, and the gingival crevice region of 20 patients with pss. | 2001 | 11361180 |
| occurrence of prevotella intermedia and prevotella nigrescens in relation to gingivitis and gingival health. | the occurrence of prevotella intermedia (pi) and prevotella nigrescens (pn) in relation to natural gingivitis, gingival health and 14-day experimental gingivitis was investigated in 25 non-dental students. | 2001 | 11168745 |
| antimicrobial activity of tannin components from vaccinium vitis-idaea l. | reactive oxygen species have been implicated as important pathological mediators in many clinical disorders, including periodontal disease. as a possible alternative for the treatment of periodontal disease, the antimicrobial activity of six tannins isolated from vaccinium vitis-idaea l., with confirmed antioxidant activity, were assayed by the agar dilution method against selected periodontal pathogens, actinobacillus actinomycetemcomitans, porphyromonas gingivalis and prevotella intermedia. th ... | 2001 | 11273014 |
| smoking and subgingival microflora in periodontal disease. | the present investigation was undertaken to analyze the influence of smoking on the periodontal disease associated subgingival microflora. the population included 33 smokers and 31 non-smokers in the age range 36-86 years. | 2001 | 11284533 |
| immunopathological diagnosis of cicatricial pemphigoid with desquamative gingivitis. a case report. | cicatricial pemphigoid (cp) is a chronic subepidermal bullous dermatosis which primarily involves the mucous membranes. the oral cavity and the eye are most frequently involved. since extension of the lesion into the pharynx and esophagus causes sore throat and dysphagia and progressive ocular lesions may cause blindness, early and valid diagnosis is very important. here we present a case of cicatricial pemphigoid with onset at age 45 in a patient who manifested severe periodontal disease and sh ... | 2001 | 11288799 |
| periodontal pathogens produce quorum sensing signal molecules. | different species of bacteria important in the composition of dental plaque were tested for production of extracellular autoinducer-like activities that stimulate the expression of the luminescence genes in vibrio harveyi. several strains of prevotella intermedia, fusobacterium nucleatum, and porphyromonas gingivalis were found to produce such activities. interestingly, these bacteria belong to the same phylogenetic group, and they are periodontal pathogens important in the development of period ... | 2001 | 11292769 |
| recovery of anaerobic bacteria from 3 patients with infection at a pierced body site. | we describe 3 adolescents who developed infections due to anaerobes at pierced body sites: the nipple, the umbilicus, and the nasal septum. anaerobes (prevotella intermedia and peptostreptococcus anaerobius) were recovered from pure culture of specimens obtained from 1 patient with nipple infection and were mixed with aerobic bacteria in cultures of specimens obtained from 2 patients (streptococcus aureus, peptostreptococcus micros, and prevotella melaninogenica were recovered from a patient wit ... | 2001 | 11389513 |
| smoking affects the subgingival microflora in periodontitis. | tobacco smoking has been identified as one major risk factor for destructive periodontal disease. scaling and root planing have been shown to be less effective in smokers with periodontitis. the aim of the present study was to compare the subgingival microbial flora of treated and untreated smokers and non-smokers. | 2001 | 11394403 |
| antibacterial activity of particulate bioglass against supra- and subgingival bacteria. | particulate bioglass is a bioactive material used in the repair of periodontal defects. this material undergoes a series of surface reactions in an aqueous environment which lead to osseointegration. the aim of this study was to determine whether these reactions exerted an antibacterial effect on a range of oral bacteria. streptococcus sanguis, streptococcus mutans and actinomyces viscosus were suspended in nutrient broth (nb), artificial saliva (as) or dulbecco's modified eagle medium plus 10% ... | 2001 | 11374470 |
| the effect of oral bacteria on candida albicans germ-tube formation. | a total of eight bacterial isolates belonging to six species, and a select group of 12 oral candida albicans isolates, were used to study the effect of bacteria on germ-tube formation. briefly, each bacterial suspension (10(5-6) cells/ml) was mixed with a c. albicans suspension (10(7) cells/ml) and incubated at 37 degrees c for 90 min with bovine serum, and the percentage germ-tube-positive candida cells was quantified using a haemocytometer, under light microscopy. in general, out of eight bact ... | 2001 | 11398996 |
| inhibitory effect of lactoperoxidase-generated hypothiocyanite upon black pigmented anaerobe growth. | this study aimed to evaluate the in vitro effect of lactoperoxidase with or without its substrates (hydrogen peroxide, thiocyanate) on the growth of 4 different black pigmented anaerobe (bpa) strains associated with the development and progress of periodontal diseases: porphyromonas gingivalis atcc 33277, prevotella intermedia nctc 9336, prevotella loescheii atcc 15930, and prevotella melaninogenica nctc 9338. a 5-min lactoperoxidase-generated oscn--hoscn incubation at ph 6.0, 7.0 or 8.0 resulte ... | 2001 | 11408950 |
| microbiological characteristics of subgingival microbiota in adult periodontitis, localized juvenile periodontitis and rapidly progressive periodontitis subjects. | to describe the prevalence of the cultivable subgingival microbiota in periodontal diseases and to draw attention to the polymicrobial nature of periodontic infections. | 2001 | 11422244 |
| untreated periodontal disease in indonesian adolescents. subgingival microbiota in relation to experienced progression of periodontitis. | in an indonesian population deprived of regular dental care, the experienced progression of disease between baseline (1987) and follow-up (1994) was investigated in relation to the composition of the subgingival microbiota at follow-up. at baseline the age ranged from 15 to 25 years. clinical and microbiological evaluation was completed in 158 of the 167 subjects available at follow-up. | 2001 | 11422582 |
| mutans streptococci in subgingival plaque of treated and untreated patients with periodontitis. | the etiology of root caries is thought to be identical to coronal caries, though root caries seem to be more complicated because of the higher susceptibility of exposed roots (dentin) by periodontal therapy to demineralization than intact enamel. this implies that mutans streptococci are the most likely pathogens in the development of root caries. although it is known that both the numbers of mutans streptococci and the frequency of isolation in root caries lesions are negatively correlated with ... | 2001 | 11422591 |
| molecular detection of black-pigmented bacteria in infections of endodontic origin. | a 16s rdna-directed polymerase chain reaction method was used to assess the occurrence of four black-pigmented anaerobic rods in root canal infections. samples were obtained from 54 infected teeth. ten cases were diagnosed as acute periradicular abscesses. dna was extracted from the samples and analyzed using a polymerase chain reaction-based identification assay. the method allowed detection of black-pigmented bacteria anaerobes in 59.3% of the examined teeth. twelve cases yielded more than one ... | 2001 | 11556558 |
| clinical significance of antibiotic therapy in guided tissue regeneration with a resorbable membrane. | this study was designed to evaluate the clinical significance of antibiotic therapy combined with guided tissue regeneration (gtr) therapy with a collagen membrane. the subjects were 20 adults diagnosed with periodontitis (20 intrabony periodontal defects). ten patients were treated with gtr alone (control group) and the other 10 patients were treated with a combination of gtr and antibiotics (antibiotic group). in the antibiotic group, minocycline ointment was applied locally before gtr therapy ... | 2001 | 11575110 |
| performance of a commercial immunoassay for detection and differentiation of periodontal marker bacteria: analysis of immunochemical performance with clinical samples. | we employed a commercial immunoassay for simultaneous detection and differentiation of marker bacteria actinobacillus actinomycetemcomitans, porphyromonas gingivalis, and prevotella intermedia and reassessed the immunochemical performance of the assay. | 2001 | 11577952 |
| effects of smoking and treatment status on periodontal bacteria: evidence that smoking influences control of periodontal bacteria at the mucosal surface of the gingival crevice. | we examined whether smoking status could influence growth of potentially pathogenic bacteria in the periodontal environment of treated and untreated periodontal patients. | 2001 | 11577953 |
| periodontal infections contribute to elevated systemic c-reactive protein level. | periodontitis is a local inflammatory process mediating destruction of periodontal tissues triggered by bacterial insult. however, this disease is also characterized by systemic inflammatory host responses that may contribute, in part, to the recently reported higher risk for cardiovascular disease (cvd) among patients with periodontitis. moderate elevation of c-reactive protein (crp) has been found to be a predictor of increased risk for cvd. elevated crp levels in periodontal patients have bee ... | 2001 | 11577954 |
| [clinical and microbiological study of adult periodontal disease]. | the aim of this study was to carry out a microbiological evaluation of sites with and without clinical evidence of moderate and severe periodontitis and their correlation with clinical parameters. a total of 52 disease sites and 10 healthy sites were selected according to clinical criteria. the following clinical indexes were measured for all the sites: plaque index, gingival index, blood on probing, depth on probing and insertion level. samples of subgingival plaque were collected for culture a ... | 2001 | 11594003 |
| microbiological evaluation of acute periradicular abscesses by dna-dna hybridization. | the purpose of the present investigation was to examine the microbiota of acute periradicular abscesses of endodontic origin by using a molecular genetic method. | 2001 | 11598583 |
| susceptibilities of eikenella corrodens, prevotella intermedia, and prevotella nigrescens clinical isolates to amoxicillin and tetracycline. | the ab biodisk etest showed that 106 (100%) and 98 (92%) isolates of eikenella corrodens were susceptible to amoxicillin and tetracycline, respectively. twenty-three (68%) prevotella intermedia isolates and 14 (67%) prevotella nigrescens isolates were susceptible to amoxicillin. seventy-nine percent of the p. intermedia isolates and 67% of the p. nigrescens isolates were susceptible to tetracycline. a higher percentage of beta-lactamase-producing isolates of p. intermedia and p. nigrescens were ... | 2001 | 11600394 |
| efficacy of manual and powered toothbrushes (ii). effect on microbiological parameters. | the purpose of the present investigation was to determine the effect of self-performed supragingival plaque removal using either manual (crest complete) or power (braun 3d plaque remover) toothbrushing on supra and subgingival plaque composition. | 2001 | 11686813 |
| absence of a specific subgingival microflora in adults with down's syndrome. | periodontal disease in down's syndrome (ds) is generally characterized by a high degree of bone loss. bone loss of 5 mm or more is observed in 70% of these subjects. among ds subjects, considerable differences in disease progression occur. so far, no studies have been conducted in which specific properties of the subgingival microflora have been related to the condition observed. | 2001 | 11686820 |
| coaggregation of porphyromonas gingivalis and prevotella intermedia. | porphyromonas gingivalis cells coaggregated with prevotella intermedia cells. the coaggregation was inhibited with l-arginine, l-lysine, nalpha-p-tosyl-l-lysine chloromethyl ketone, trypsin inhibitor, and leupeptin. heat- and proteinase k-treated p. gingivalis cells showed no coaggregation with p. intermedia cells, whereas heat and proteinase k treatments of p. intermedia cells did not affect the coaggregation. the vesicles from p. gingivalis culture supernatant aggregated with p. intermedia cel ... | 2001 | 11694077 |
| [effect of supragingival plaque control on subgingival microflora and periodontal tissues]. | the aim of this study was to investigate, clinically and microbiologically, forty-four sites in 11 patients presenting with generalized chronic periodontitis. plaque index (pi), gingival index (gi), probing bleeding (pb), probing depth (pd) and insertion level (il) were registered. samples of subgingival plaque were collected in the same sites for cultivation of anaerobic bacteria and determination of microbiological morphotypes using dark field microscopy. clinical and microbiological data were ... | 2001 | 11705193 |
| intra- and interspecies regulation of gene expression by actinobacillus actinomycetemcomitans luxs. | the cell density-dependent control of gene expression is employed by many bacteria for regulating a variety of physiological functions, including the generation of bioluminescence, sporulation, formation of biofilms, and the expression of virulence factors. although periodontal organisms do not appear to secrete acyl-homoserine lactone signals, several species, e.g., porphyromonas gingivalis, prevotella intermedia, and fusobacterium nucleatum, have recently been shown to secrete a signal related ... | 2001 | 11705942 |
| a longitudinal study of interleukin-1 gene polymorphisms and periodontal disease in a general adult population. | cross-sectional studies have demonstrated that a specific polymorphism (allele 2 of both il-1a +4845 and il-1b +3954) in the il-1 gene cluster has been associated with an increased susceptibility to severe periodontal disease and to an increased bleeding tendency during periodontal maintenance. the aim of the present study was to investigate the relationship between il-1 genotype and periodontitis in a prospective longitudinal study in an adult population of essentially european heritage. | 2001 | 11737511 |
| distribution of actinobacillus actinomycetemcomitans, porphyromonas gingivalis and prevotella intermedia in an australian population. | the present study describes (i) the natural distribution of the three putative periodontopathogens porphyromonas gingivalis, prevotella intermedia and actinobacillus actinomycetemcomitans in an australian population and (ii) the relationship between these organisms, pocket depths and supragingival plaque scores. | 2001 | 11737515 |
| lactoferrin, amylase and mucin muc5b and their relation to the oral microflora in hyposalivation of different origins. | there are several reasons for hyposalivation, each affecting the salivary composition in different ways. the aim of this study was to analyze and compare lactoferrin, amylase and mucin muc5b in stimulated whole saliva collected from subjects with hyposalivation of different origins and to relate the results to the presence of some microbial species associated with oral disorders. albumin was determined as a marker of serum leakage. the characteristic feature for subjects with radiation-induced h ... | 2001 | 11737657 |
| inflammatory reactions in extraoral tissues in mice after intragingival injection of lipopolysaccharide. | intragingival (ig) injection into mice of lipopolysaccharide (lps) from prevotella intermedia or escherichia coli elevated the activity of the histamine-forming enzyme, histidine decarboxylase (hdc), in the mandible, liver, lung, and spleen, with a time course similar to that seen with intravenous (iv) injection. the effect of i.g. injection was less than that of i.v. injection but similar to that of intraperitoneal (ip) injection. the i.g. injection also increased hepatic serotonin, reflecting ... | 2001 | 11740732 |
| associations between serum antibody levels to periodontal pathogens and early-onset periodontitis. | the role of antibodies to periodontal microorganisms in the development of periodontal tissue destruction is still unclear. the aim of this study was to investigate the association between serum levels of igg, iga, and igm antibodies to 6 periodontal microorganisms and clinical subtypes of varying severity of early-onset periodontitis (eop) in young african american adults. | 2001 | 11759856 |
| effects of glucose on formation of cytotoxic end-products and proteolytic activity of prevotella intermedia, prevotella nigrescens and porphyromonas gingivalis. | black-pigmented bacteria which produce cytotoxic metabolic end-products and cell membrane-associated proteases have been reported to play an important role in the pathogenesis of periodontal diseases. these bacterial virulence factors can be modified by the environmental conditions including nutrients supplied variously into the oral cavity. although glucose is one of the most essential nutrients for oral bacteria, the exogenous supply of glucose may be discontinuous and the glucose concentratio ... | 2001 | 11762870 |
| amoxicillin plus metronidazole in the treatment of adult periodontitis patients. a double-blind placebo-controlled study. | the aim of this double-blind, parallel study was to evaluate the adjunctive effects of systemically administered amoxicillin and metronidazole in a group of adult periodontitis patients who also received supra- and subgingival debridement. | 2001 | 11314884 |
| isolation and genotyping of black-pigmented anaerobes from periodontal sites of hiv-positive and non-infected subjects in thailand. | the aims of this study were to investigate the prevalence of periodontitis, the prevalence of black-pigmented anaerobes and the genotypes of porphyromonas gingivalis and prevotella intermedia present in hiv-infected and control subjects in a heterosexual thai population. | 2001 | 11314886 |
| crosslaps and beta-glucuronidase in peri-implant and gingival crevicular fluid. | collagen degradation products of the carboxyterminal region possibly reflect bone and attachment loss. in the present study, the serum crosslaps one-step enzyme-linked immunosorbent assay was used to determine a specific part of the carboxyterminal region of type i collagen, the crosslaps. samples of peri-implant and gingival crevicular fluid of 111 implants and 53 teeth from 47 partially or completely edentulous patients were examined in reference to levels of crosslaps and beta-glucuronidase ( ... | 2001 | 11324213 |
| relationship of periodontopathic bacteria with early-onset periodontitis in down's syndrome. | down's syndrome (ds) patients often develop severe early-onset marginal periodontitis in early adulthood; however, there is little information available on the microbiology of ds periodontitis. | 2001 | 11327065 |
| antimicrobial activity of silver nitrate against periodontal pathogens. | metal ions were evaluated as potential antimicrobial agents suitable for local delivery in the oral cavity for the treatment of periodontitis. silver nitrate, copper chloride, and zinc chloride were tested for antimicrobial activity in in vitro killing assays conducted in phosphate buffered saline with a series of oral bacteria including gram-negative periodontal pathogens and gram-positive streptococci. copper and zinc salts failed to exhibit strong and consistent activity against periodontal p ... | 2001 | 11327077 |
| a microbiological study of papillon-lefévre syndrome in two patients. | to analyse the microflora of subgingival plaque from patients with papillon-lefévre syndrome (pls), which is a very rare disease characterised by palmar-plantar hyperkeratosis with precocious periodontal destruction. | 2001 | 11328836 |
| move of adults with mental retardation from institutions to community-based living: changes in the oral microbiological flora. | in the western world, the policy of deinstitutionalization and integration of individuals with mental retardation is generally accepted. we tested the hypothesis that de-institutionalization may lead to changes of habits with a potential to influence oral health. when 57 adults with mental retardation moved from an institution to community-based living, their oral hygiene habits, gingival bleeding, and a three-day food record were registered one month before and 9 and 21 months after the move. m ... | 2001 | 11332525 |
| relationship of cigarette smoking to the subgingival microbiota. | the relationship of cigarette smoking to the composition of the subgingival microbiota is not clear. some studies indicated higher levels of certain species in smokers, while other studies failed to detect differences in the microbiota between subjects with different smoking histories. thus, the purpose of the present investigation was to examine the prevalence, proportions and levels of the subgingival species in adult subjects who were current, past or never smokers. | 2001 | 11350499 |
| clinical and microbial evaluation of a histatin-containing mouthrinse in humans with experimental gingivitis. | p-113, a 12 amino acid histatin-based peptide, was evaluated in a mouthrinse formulation for safety, prevention of the development of experimental gingivitis, and for its effects on periodontal flora. | 2001 | 11350502 |
| the effect of systemic antibiotics in the treatment of patients with recurrent periodontitis. | subjects with periodontal disease exist who either (i) respond poorly to initial mechanical therapy ("refractory" periodontitis) or (ii) fail to adopt adequate self-performed plaque control techniques and hence develop recurrent disease ("recurrent" periodontitis) at multiple sites during the supportive treatment phase (spt). various systemic antibiotic regimens have been tried as adjuncts to the mechanical (re-) treatment of such "difficult to treat"-patients. while most studies indicated a pos ... | 2001 | 11350503 |
| effect of non-surgical periodontal treatment on clinical parameters and the numbers of porphyromonas gingivalis, prevotella intermedia and actinobacillus actinomycetemcomitans at adult periodontitis sites. | the purpose of this study was to relate the numbers of porphyromonas gingivalis, prevotella intermedia and actinobacillus actinomycetemcomitans cells to clinical parameters at diseased and healthy periodontal sites before and after non-surgical periodontal therapy using a sensitive quantitative pcr method (q-pcr). | 2001 | 11350507 |
| pcr detection of 5 putative periodontal pathogens in dental plaque samples from children 2 to 12 years of age. | the purpose of this study was to detect the presence of prevotella intermedia, p. nigrescens, bacteroides forsythus, treponema denticola, and campylobacter rectus in plaque samples from 119 children, collected from their toothbrushes using a polymerase chain reaction (pcr). | 2001 | 11350526 |
| the influence of intracrevicular crown margins on gingival health: preliminary findings. | the effect on gingival tissue of various crown materials in combination with different abutment biomaterials should be investigated. | 2001 | 11357072 |
| microbial analysis of bone collected during implant surgery: a clinical and laboratory study. | dental implant surgery produces bone debris which can be used to correct bone defects in the "simultaneous-augmentation" technique. however, this debris is potentially contaminated with oral bacteria. therefore, this study examined bone debris collected during dental implant surgery in order 1) to identify the microbial contaminants and 2) to compare the effects of two different aspiration protocols on the levels of microbial contamination. twenty-four partially dentate patients were randomly al ... | 2001 | 11251657 |
| lethal photosensitization for decontamination of implant surfaces in the treatment of peri-implantitis. | peri-implantitis is considered to be a multifactorial process involving bacterial contamination of the implant surface. a previous study demonstrated that a combination of toluidine blue o (100 microgram/ml) and irradiation with a diode soft laser with a wavelength of 905 nm results in an elimination of porphyromonas gingivalis (p. gingivalis), prevotella intermedia (p. intermedia), and actinobacillus actinomycetemcomitans (a. actinomycetemcomitans) on different implant surfaces (machined, plasm ... | 2001 | 11251658 |
| antimicrobial activity of honokiol and magnolol isolated from magnolia officinalis. | the antimicrobial activity of honokiol and magnolol, the main constituents of magnolia officinalis was investigated. the antimicrobial activity was assayed by the agar dilution method using brain heart infusion medium and the minimum inhibitory concentration (mic) were determined for each compound using a twofold serial dilution assay. the results showed that honokiol and magnolol have a marked antimicrobial effect (mic = 25 microg/ml) against actinobacillus actinomycetemcomitans, porphyromonas ... | 2001 | 11268114 |
| a multidisciplinary approach to the diagnosis and treatment of early-onset periodontitis: a case report. | the diagnosis and treatment of early-onset forms of periodontitis (eop) represent a major challenge to periodontists. in this case report, we describe a multidisciplinary approach for the treatment of a patient with severe generalized juvenile periodontitis (gjp). our approach incorporates clinical laboratory evaluation with conventional concepts of periodontal pathogenesis and therapeutics to diagnose and effectively treat eop. | 2001 | 11210080 |
| interleukin-6 deficiency increases inflammatory bone destruction. | periapical bone destruction occurs as a consequence of pulpal infection. in previous studies, we showed that interleukin-1 (il-1) is the primary stimulator of bone destruction in this model. il-6 is a pleiotropic cytokine that is induced in these infections and has both pro- and anti-inflammatory activities. in the present study, we determined the role of il-6 in regulating il-1 expression and bone resorption. the first molars of il-6 knockouts (il-6(-/-)) and wild-type mice were subjected to su ... | 2001 | 11159963 |
| one-year compliance and effects of amine and stannous fluoride on some salivary biochemical constituents and oral microbes in institutionalized elderly. | due to old age and poor general health, the institutionalized elderly have often not been used as research subjects for the investigation of oral health protocols. because the number of elderly is increasing, they are an important target group for the development of oral hygiene aids. this trial was designed to investigate whether the institutionalized elderly could successfully use an amine-fluoride- and stannous-fluoride-containing mouthwash and toothpaste during a 12-month period. a dental hy ... | 2001 | 11795450 |
| regulation of phospholipase c-gamma 2 via phosphatidylinositol 3-kinase in macrophages. | phospholipase c-gamma (plc-gamma) isoforms are thought to be activated by both tyrosine phosphorylation and phosphatidylinositol 3,4,5 trisphosphate (ptdins 3,4,5 p(3)), the product of phosphatidylinositol 3-kinase (ptdins 3-kinase). in this study, we show that stimulation of mouse macrophages with either zymosan beads or bacteria (prevotella intermedia) induced tyrosine phosphorylation of plc-gamma 2. zymosan stimulation also induced translocation to membrane and cytoskeleton fractions, which w ... | 2002 | 11781142 |
| suppurative parotitis caused by anaerobic bacteria in newborns. | staphylococci are the usual bacterial etiology of suppurative parotitis in newborns. this report describes for the first time recovery of anaerobic bacteria from aspirates of the infected gland in two infants with suppurative parotitis. peptostreptococcus intermedius and prevotella melaninogenica were isolated from one child and prevotella intermedia from the other patient. complete recovery occurred after 4 weeks of antimicrobial therapy. | 2002 | 11791111 |
| igg subclass specific antibody response to periodontopathic organisms in hiv-positive patients. | we previously reported an increased rate of progression of periodontal disease over an 18-month period in human immunodeficiency virus (hiv)-positive subjects compared to controls. the mechanism for disease progression and rapid tissue loss was unknown. data on the microbiological studies failed to show any significant difference in the microbial characteristics of the periodontal lesions in hiv-positive patients compared to hiv-negative controls. immunological analysis had identified neutrophil ... | 2002 | 12546094 |
| isotypic antibody response to plaque anaerobes in periodontal disease. | it has been suggested that locally produced immunoglobulin (ig)a could be more protective than igg and that there could be a relationship between crevicular fluid-specific iga levels and the onset of periodontal disease. this study was designed to investigate this hypothesis regarding specific immune responses towards 4 plaque anaerobes in gingival crevicular fluid and saliva from patients with periodontopathies and controls. | 2002 | 12546101 |
| evaluation of antibacterial activity of mangifera indica on anaerobic dental microglora based on in vivo studies. | the present study was carried out to compare the subgingival plaque microflora in mango leaf users. fifty subjects of both sexes, 25 of them used tooth brush and 25 used mango leaf as their home care hygiene device were included in the study. the microbiological evaluation for specific bacterial counts of actinobacillus actinomycetemcomitans, prevotella intermedia, porphyromonas gingivalis, fusobacterium nucleatum and peptostreptococcus micros were carried out for all subject. specific microbial ... | 2002 | 12785172 |
| can presence or absence of periodontal pathogens distinguish between subjects with chronic and aggressive periodontitis? a systematic review. | the purpose of this study was to determine to what extent the presence or absence of periodontal pathogens can distinguish between subjects with chronic and aggressive periodontitis. | 2002 | 12787203 |
| activation of human gingival epithelial cells by cell-surface components of black-pigmented bacteria: augmentation of production of interleukin-8, granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor and expression of intercellular adhesion molecule 1. | black-pigmented anaerobic bacteria, such as porphyromonas gingivalis and prevotella intermedia, are amongst the predominant bacteria in periodontal pockets and have been implicated in periodontal diseases. to elucidate the roles of gingival keratinocytes, which are the first cells encountered by oral bacteria in periodontal diseases, human gingival keratinocytes in primary culture were stimulated with cell-surface components of p gingivalis and pr. intermedia. a glycoprotein fraction from pr. in ... | 2002 | 11800468 |
| periapical lesion progression with controlled microbial inoculation in a type i diabetic mouse model. | uncontrolled or poorly controlled diabetes mellitus may be a risk factor for the development of large and/or debilitating periapical infections. the objectives of this investigation were to: (i) determine the effect of diabetes mellitus on the pathogenesis of periapical lesions with or without specific bacterial inoculations at the exposure sites, and (ii) test the sensitivities of two microbiological techniques in detecting the persistence of the bacterial inoculum in exposed pulps of nonobese ... | 2002 | 11806653 |
| distribution of erm(f) and tet(q) genes in 4 oral bacterial species and genotypic variation between resistant and susceptible isolates. | bacteroides forsythus, porphyromonas gingivalis and prevotella intermedia are gram-negative anaerobic bacteria that are currently considered potential periopathogens. prevotella nigrescens has recently been separated from p. intermedia and its rôle in periodontitis is unknown. the erm(f) gene codes for an rrna methylase, conferring resistance to macrolides, lincosamides and streptogramin b (mlsb), and the tet(q) gene for a ribosomal protection protein, conferring resistance to tetracycline. the ... | 2002 | 11895543 |
| clinical and microbiological studies of periodontal disease in sjögren syndrome patients. | little is known about the periodontal status of patients with sjögren's syndrome (ss), a chronic inflammatory autoimmune disease characterized by xerophthalmia and xerostomia. the aim of the present study was to evaluate whether the periodontal status of ss patients, in terms of clinical and microbiological parameters, differs from systemically healthy age- and gender-matched controls. | 2002 | 11908470 |
| long-term follow-up of osseointegrated titanium implants using clinical, radiographic and microbiological parameters. | the aim of this study was to longitudinally follow up osseointegrated titanium implants in partially dentate patients by clinical, radiographic and microbiological parameters in order to evaluate possible changes in the peri-implant health over time. fifteen individuals treated with titanium implants, ad modum brånemark, and followed for ten years were included in the study. before implant placement ten years previously, the individuals had been treated for advanced periodontal disease and there ... | 2002 | 11952732 |
| adjunctive effects to non-surgical periodontal therapy of systemic metronidazole and amoxycillin alone and combined. a placebo controlled study. | several studies have reported adjunctive benefits to scaling and root planing (srp) of systemic amoxycillin and metronidazole in the treatment of periodontal diseases. to date no comparisons have been made of these antimicrobials alone or in combination. the aim of this study was to compare the adjunctive benefits to srp of amoxycillin and metronidazole alone and combined. | 2002 | 11966932 |
| [identification of periodontopathic bacteria dna from periodontitis-involved gingival tissue using a pcr method]. | the purpose of this study was to determine the presence of periodontopathic bacteria dna in the granulation tissue of periodontally involved gingival tissue. forty periodontitis patients were examined. subgingival plaque and saliva samples were collected from the patients before surgery. then, granulation tissue was also collected during surgery. another 20 patients, who had more than 4 mm in probing pocket depth, were also examined as a control. they received only initial treatment without peri ... | 2002 | 11968834 |
| effect of fusobacterium nucleatum on the t and b cell responses to porphyromonas gingivalis in a mouse model. | t cell cytokine profiles and specific serum antibody levels in five groups of balb/c mice immunized with saline alone, viable fusobacterium nucleatum atcc 25586, viable porphyromonas gingivalis atcc 33277, f. nucleatum followed by p. gingivalis and p. gingivalis followed by f. nucleatum were determined. splenic cd4 and cd8 cells were examined for intracytoplasmic interleukin (il)-4, interferon (ifn)-gamma and il-10 by dual colour flow cytometry and the levels of serum anti-f. nucleatum and anti- ... | 2002 | 11985513 |
| direct quantitative differentiation between prevotella intermedia and prevotella nigrescens in clinical specimens. | this paper describes a quantitative fluorescent in situ hybridization (fish) assay for the differential identification of prevotella intermedia and prevotella nigrescens in clinical samples, and compares its performance with less discriminatory culture and quantitative immunofluorescence (if) assays. fluorescence-labelled oligonucleotide probes directed to specific 16s rrna sequences of p. intermedia, p. nigrescens, prevotella pallens and prevotella denticola were hybridized under stringent cond ... | 2002 | 11988511 |
| the effects of an immediately pre-surgical chlorhexidine oral rinse on the bacterial contaminants of bone debris collected during dental implant surgery. | dental implant surgery produces bone debris that can be used in the "simultaneous augmentation" technique. although this debris is contaminated with oral bacteria, a stringent aspiration protocol has been shown to reduce the levels of contamination. chlorhexidine mouthrinse is a well-proven antibacterial rinse that has been shown to reduce infectious complications associated with dental implants. this study examined the effect of pre-operative rinsing with a 0.1% chlorhexidine digluconate mouthr ... | 2002 | 12005141 |