Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| bacteriophage t4 head morphogenesis. 3. some novel properties of gene 13-defective heads. | the nature of phage precursors in gene 13-defective infected cells was studied by electron microscopy and pulse-chase isotopic labeling experiments. our results suggest that both stable (20%) and fragile (70%) filled-head precursors accumulated in the absence of gene 13 product. upon extraction, the fragile heads were found to lose most of their deoxyribonucleic acid and appeared unfilled with an average density of 1.34 g/cm(3) and a sedimentation coefficient of 300s. these unfilled heads differ ... | 1972 | 4113885 |
| nuclear disruption after infection of escherichia coli with a bacteriophage t4 mutant unable to induce endonuclease ii. | nuclear disruption after infection of escherichia coli with a bacteriophage t4 mutant deficient in the ability to induce endonuclease ii indicates that either (i) the endonuclease ii-catalyzed reaction is not the first step in host deoxyribonucleic acid (dna) breakdown or (ii) nuclear disruption is independent of nucleolytic cleavage of the host chromosome. m-band analysis demonstrates that the host dna remains membrane-bound after infection with either an endonuclease ii-deficient mutant or t4 ... | 1972 | 4114321 |
| serum pattern of thyroxine (t4) and triiodothyronine (t3) after treatment of thyrotoxicosis with antithyroid drugs. | 1972 | 4114923 | |
| [evaluation of the simple determination of serum t4-i by west's method]. | 1972 | 4115660 | |
| mouse thymus-independent and thymus-derived lymphoid cells. i. immunofluorescent and functional studies. | the simultaneous use on mouse lymphoid suspensions of heterologous antisera directed against thymus-derived (t) cell mouse-specific lymphocyte antigen and brain-associated theta antigen (msla and batheta) or thymus-independent (b) cell mouse-specific bone marrow-derived lymphocyte antigen (mbla) surface antigens allowed direct proof of the different specificity of these antisera by double immunofluorescence (if) staining with selective visualization of fluorochromes. these antisera and antisera ... | 1972 | 4117194 |
| detection of polyadenylic acid sequences in viral and eukaryotic rna(polu(u)-cellulose columns-poly(u) filters-fiberglass-hela cells-bacteriophage t4). | a rapid and specific technique to detect polyriboadenylic acid sequences in rna is described. the method depends upon the ability of rnas that contain poly(a) sequences to associate specifically with poly(u) that has been immobilized on fiberglass filters by ultraviolet irradiation. a high proportion of the transcripts synthesized in vivo and in vitro from the vaccinia virus genome contain poly(a) sequences and bind to the poly(u) filters. similarly, dna-like rna from the nucleus and from the cy ... | 1972 | 4501121 |
| t4 transfer rnas: codon recognition and translational properties. | t4 phage transfer rnas recognize the previously assigned codons for a given amino acid; however, they tend to prefer code words that are less well recognized by their host. the phage transfer rnas are more effective in polypeptide synthesis with t4 rather than escherichia coli messenger rnas. | 1972 | 4504324 |
| osmotic injury in rapidly thawed t4 bacteriophage. | osmotic injury in frozen-thawed t4 phage was caused by the sudden and large fall in the electrolyte concentration of the unfrozen aqueous phase during rapid thawing of frozen samples. in accordance with the classical interpretation of osmotic shock it was found that dna was quantitatively liberated from t4 phage inactivated by the osmotic injury of rapid thawing.the degree of inactivation of osmotically shocked t4 phage was temperature dependent, being much increased by lowering the temperature, ... | 1972 | 4506994 |
| protection of t4 bacteriophage against inactivation during freezing and thawing by addition of peptides. | peptides of rabbit globin produced by tryptic digestion, were found to be highly protective against inactivation of freeze-thawed t4 phage. in concentrations of about 10(-3) m the peptides protected the phage against inactivation by both concentrated nabr in the unfrozen aqueous phase and the eutectic phase change.fractionation of the peptides by g25 sephadex showed that peptide concentration rather than peptide size was the more important factor in determining the degree of protection of the ph ... | 1972 | 4506995 |
| bacteriophage t4 trna leu . | 1972 | 4508375 | |
| an alternative approach to the study of new enzymatic reactions involving dna (dna-dependent atpases-purification-properties-e. coli). | ordinarily, enzymes that catalyze bimolecular reactions involving dna and nucleoside triphosphates are assayed in terms of the predicted changes in dna. however, by assay of the enzymes by changes in nucleoside triphosphates, new enzymes may be sought without prior knowledge of the role of dna in the reaction. this approach was used to isolate two new enzymes from escherichia coli and one from t4 phage-infected e. coli. in this communication, the general application of this technique and its spe ... | 1972 | 4258317 |
| the time of synthesis and function of the rii + product of bacteriophage t4. | 1972 | 4261045 | |
| hydroxyurea-sensitive mutants of bacteriophage t4. | 1972 | 4263604 | |
| control of the synthesis of t4 phage deoxynucleotide kinase messenger ribonucleic acid in vivo. | 1972 | 4264135 | |
| initiation of bacillus subtilis ribonucleic acid polymerase on deoxyribonucleic acid from bacteriophages 2c, phi 29, t4, and lambda. | ribonucleic acid (rna) synthesis primed by bacteriophage t4 or lambda deoxyribonucleic acid (dna) with bacillus subtilis rna polymerase is severely inhibited by high ionic strength. in contrast, rna synthesis on b. subtilis bacteriophage 2c, spo1, or phi29 dna is only moderately affected under similar conditions. the basis of this inhibition lies in the inability of the enzyme to initiate rna chains with adenosine triphosphate or guanosine triphosphate (atp, gtp). binding to templates and the ra ... | 1972 | 4204905 |
| genetic location of a mutant of bacteriophage t4 deficient in the ability to induce endonuclease ii. | reciprocal three-factor crosses and the use of a partial revertant of a putative ribonucleotide reductase mutant of escherichia coli b/5 as indicator have made it possible to map dena (deficient in endonuclease ii) between nrd-11 (ribonucleotide reductase gene b) and amm69 (gene 63) on the bacteriophage t4 chromosome. | 1972 | 4333540 |
| mechanism of dna chain growth. vii. direction and rate of growth of t4 nascent short dna chains. | 1972 | 4335583 | |
| identification and genetic characterization of mutants of bacteriophage t4 defective in the ability to induce exonuclease a. | a mutant of bacteriophage t4 unable to induce exonuclease a has been isolated. the mutation responsible for this defect maps between genes 39 and 56, in a region of the chromosome devoid of other known markers. four deletion mutants lacking part of the genome located between genes 39 and 56 also fail to induce exonuclease a. the ability of all of these mutants to replicate suggests that exonuclease a is not essential for replication of phage t4. | 1972 | 4335658 |
| properties of phage t4 messenger rna synthesized in the absence of protein synthesis. | 1972 | 4335933 | |
| electron microscopic studies on substrate specificity of t4 excision repair endonuclease. | 1972 | 4337868 | |
| stability of cytosine-containing deoxyribonucleic acid after infection by certain t4 rii-d deletion mutants. | when t-even phage infect escherichia coli, synthesis of host deoxyribonucleic acid (dna) rapidly ceases. if the phage carry a mutation in a gene essential for phage dna synthesis, then the infected bacteria should make no dna, either host dna or phage dna. however, we have found that infection with certain t4 gene 56 (deoxycytidine triphosphatase)-rii double mutants leads to substantial dna synthesis. only rii deletion mutations which extend into the middle third of the adjacent, nonessential d ... | 1972 | 4339199 |
| biochemical changes during mixed infections with bacteriophages t2 and t4. | 1972 | 4342040 | |
| nucleoside-coated bacteriophage t4: a method for the detection and characterization of anti-nucleoside antibodies. | 1972 | 4342925 | |
| purification and properties of bacteriophage t4-induced rna ligase. | an enzyme, purified 300-fold from escherichia coli infected with bacteriophage t4, catalyzes the conversion of 5'-termini of polyribonucleotides to internal phosphodiester bonds. the reaction requires atp and mg(++). for every 5'-(32)p terminus rendered resistant to alkaline phosphatase, an equal amount of amp and ppi are formed. various polyribonucleotides are substrates in the reaction; to date, the best substrate is [5'-(32)p]polyriboadenylate. with the latter substrate, no evidence of interm ... | 1972 | 4342972 |
| deoxyribonucleic acid repair in bacteriophage t4: observations on the roles of the x and v genes and of host factors. | studies were carried out to determine the effect of mutation in the host pol i gene on survival of ultraviolet (uv)-irradiated bacteriophage t4. whereas a slightly reduced survival was observed in escherichia coli strain p-3478 (pol a(1)) compared to strain w-3110 (pol a(+)), no such difference was observed in two strains isogenic except for the pol a gene. it was also shown that, whereas bacteriophage t4x is sensitive to uv irradiation, x irradiation, and treatment with methyl-methanesulfonate ... | 1972 | 4343548 |
| cleavage of simian virus 40 dna at a unique site by a bacterial restriction enzyme. | the r(1) restriction endonuclease of escherichia coli converts covalently-closed circular simian virus 40 (sv40) dna to unit-length linear duplex molecules. cleavage occurs at a unique site, since denaturation and renaturation of these linear molecules yield linear but no circular molecules. the distance from the cleavage site to the sv40 dna sequence contained in the adenovirus-sv40 hybrid, ad2(+)nd(1), is 0.11 of the length of sv40 dna. t4 gene 32 protein binds to sv40 dna in a region 0.45 of ... | 1972 | 4343967 |
| enzymatic oligomerization of bacteriophage p22 dna and of linear simian virus 40 dna. | linear double-stranded molecules of the circularly permuted and terminally redundant dna of salmonella bacteriophage p22 have been converted to oligomeric products in the presence of polynucleotide ligase coded for by the coliphage t4. the reaction has been monitored by sucrose density-gradient centrifugation and electron microscopy. it goes slowly and gives yields of 30-40%. the products are mainly dimers and trimers, but higher oligomers are also present.dna ligase extracted from uninfected es ... | 1972 | 4343970 |
| [isolation and characterization of a new t4-induced nuclease]. | 1972 | 4346461 | |
| studies on polynucleotides. cxvi. a further study of the t4 ligase-catalyzed joining of dna at base-paired ends. | 1972 | 4349756 | |
| t4 endonuclease iv. improved purification procedure and resolution from t4 endonuclease 3. | 1972 | 4550601 | |
| differential synthesis of proteins by t4 phage and its head protein amber mutant. | 1972 | 4550696 | |
| suppression of dna-arrested synthesis in mutants defective in gene 59 of bacteriophage t4. | 1972 | 4550789 | |
| activation of a defective dna polymerase in a temperature-sensitive mutant of bacteriophage t4. | 1972 | 4550900 | |
| correlation between the reduction of phage lysozyme level and the time of lysis in escherichia coli infected by bacteriophage t4. | 1972 | 4551920 | |
| new small polypeptides associated with dna-dependent rna polymerase of escherichia coli after infection with bacteriophage t4. | four new small polypeptides are associated with dna-dependent rna polymerase from e. coli after infection with t4 phage. the new polypeptides are easily detected in rna polymerase from e. coli cells labeled with amino acids after phage infection. their molecular weights range from 10,000 to 22,000, as detected by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate. all four polypeptides are found after infection with either wild-type t4 phage or t4 early amber mutants in ... | 1972 | 4551978 |
| control of pyrimidine biosynthesis by phage t4. ii. in vitro complementation between ribonucleotide reductase mutants. | 1972 | 4551996 | |
| translational regulation of deoxycytidylate hydroxymethylase and deoxynucleotide kinase synthesis in t4-infected escherichia coli. | 1972 | 4551997 | |
| bacteriophage t4 head morphogenesis. ii. studies on the maturation of gene 49-defective head intermediates. | an investigation into the metabolic requirements for maturation of gene 49-defective heads indicated that adenosine triphosphate energy and continued deoxyribonucleic acid (dna) but not ribonucleic acid synthesis were needed. the fate of dna present at restrictive temperatures (41.5 c) in tsc9 (gene 49)-infected cells was also examined. after lysis of infected cells, the 12 to 32% deoxyribonuclease-resistant dna associated with isolated gene 49-defective heads was found to be attached to a deoxy ... | 1972 | 4552417 |
| polyamines in the synthesis of bacteriophage deoxyribonucleic acid. i. lack of dependence of polyamine synthesis on bacteriophage deoxyribonucleic acid synthesis. | to determine whether polyamine synthesis is dependent on deoxyribonucleic acid (dna) synthesis, polyamine levels were estimated after infection of bacterial cells with ultraviolet-irradiated t4 or t4 am n 122, a dna-negative mutant. although phage dna accumulation was restricted to various degrees in comparison to cells infected with t4d, nearly commensurate levels of putrescine and spermidine synthesis were observed after infection, regardless of the rate of phage dna synthesis. we conclude fro ... | 1972 | 4552549 |
| polyamines in the synthesis of bacteriophage deoxyribonucleic acid. ii. requirement for polyamines in t4 infection of a polyamine auxotroph. | polyamine depletion produced by exogenous arginine in escherichia colik-12 cultures defective in agmatine ureohydrolase activity resulted in a marked inhibition of the rates of growth and nucleic acid synthesis. addition of putrescine or spermidine to such depleted cultures restored the control rate of growth and nucleic acid accumulation. the omission of lysine resulted in a further decrease in the rates of growth and nucleic acid synthesis in polyamine-depleted cells. the addition of exogenous ... | 1972 | 4552550 |
| inactivation of bacteriophage t4 by ethyl methanesulfonate: influence of host and viral genotypes. | inactivation of bacteriophage t4 by ethyl methanesulfonate (ems) is a complex process which depends critically upon the conditions of treatment and upon both the viral and the host genotypes. ems-inactivated particles are capable of multiplicity and cross-reactivation, indicating the need for caution in using ems in certain types of mutation studies. the pyrimidine dimer excision systems of the phage and the host do not affect the ems sensitivity of t4, but the t4x(+)y(+) system does. mutational ... | 1972 | 4552551 |
| bacteriophage lysozyme synthesis in escherichia coli k-12(lambda) infected with rii mutant of bacteriophage t4. | when escherichia coli k-12(lambda) was infected with a t4rii bacteriophage, synthesis of lysozyme appeared at the normal time but stopped 15 min after infection. the lysozyme produced was 1% of the normal level. | 1972 | 4552555 |
| effects of oxidized spermine and acrolein on the transforming activity of t4 dna. | 1972 | 4552901 | |
| molecular basis of a mutational hot spot in the lysozyme gene of bacteriophage t4. | 1972 | 4553645 | |
| identification of some antigenic precursors of bacteriophage t4. | 1972 | 4554113 | |
| infection of escherichia coli by t2 and t4 bacteriophages as seen in the electron microscope: t4 head morphogenesis. | bacteriophage t4 capsids seem to be assembled on e. coli protoplasmic membranes. this process seems to involve "lumps" of head protein, which convert to tau particles, which in turn give rise to empty heads. the empty heads leave the bacterial membrane and are then filled with dna in the central region of the cell. t4 gene 16 and 17 products appear to be necessary for head filling. | 1972 | 4554535 |
| on the exonuclease activity of phage t4 deoxyribonucleic acid polymerase. | 1972 | 4554914 | |
| control by bacteriophage t4 of the reduction of adenosine nucleotide to deoxyadenosine nucleotide. | 1972 | 4554915 | |
| induction of a new enzyme activity to excise pyrimidine dimers in escherichia coli infected with bacteriophage t4. | 1972 | 4555248 | |
| hydrolysis of template and newly synthesized deoxyribonucleic acid by the 3' to 5' exonuclease activity of the t4 deoxyribonucleic acid polymerase. | 1972 | 4555423 | |
| the action of bacteriophage t4 ghosts on escherichia coli and the immunity to this action developed in cells preinfected with t4. | 1972 | 4555609 | |
| a new gene of bacteriophage t4 determining immunity against superinfecting ghosts and phage in t4-infected escherichia coli. | 1972 | 4555610 | |
| effects of ionizing radiation on the capacity of escherichia coli to support bacteriophage t4 growth. | the loss in capacity of irradiated bacteria to support the growth of t4 phage has been studied for two strains, escherichia coli b and e. coli b(s-1). following a dose of 25 krads, the capacity is quite rapidly lost during postirradiation incubation so that after two hr of such incubation at 37 c only 12% remains in strain b and 3% in strain b(s-1). evidence that capacity is lost in an all-or-none fashion was provided by two types of experiments: (i) a single-burst analysis of those cells which ... | 1972 | 4556509 |
| on the direction of reading of bacteriophage t4 gene 43 (deoxyribonucleic acid polymerase). | amber (am) mutants of the two closely linked sites, b22 and c125, in bacteriophage t4 gene 43 [deoxyribonucleic acid (dna) polymerase] synthesize in the nonpermissive (su(-)) escherichia coli host gene 43 products which are devoid of dna polymerase activity, but which retain a 3'-exonuclease activity. diethylaminoethyl-cellulose chromatographic analysis of dna polymerase and deoxyribonuclease activities from extracts of su(-) cells infected with single- and double-am mutants of t4 gene 43 showed ... | 1972 | 4556512 |
| studies on t4 lysozyme. affinity for chitin and the use of chitin in the purification of the enzyme. | 1972 | 4556563 | |
| mutagenic effects of thymine dimers in bacteriophage t4. | 1972 | 4557194 | |
| triplet-state sensitization of thymine photodimerization in bacteriophage t4. | 1972 | 4557199 | |
| contribution of thymine dimers to the ultraviolet light inactivation of mutants of bacteriophage t4. | 1972 | 4557200 | |
| specificity of protein synthesis by bacterial ribosomes and initiation factors: absence of change after phage t4 infection. | 1972 | 4557601 | |
| use of immunologically modified bacteriophage t4 in detection of antibodies to nucleic acids. | 1972 | 4558243 | |
| effect of ionic strength, ph, amines and divalent cations on the lytic activity of t4 lysozyme. | 1972 | 4559097 | |
| isolation and partial characterization of a mutant of escherichia coli deficient in dna polymerase ii. | a mutant of escherichia coli deficient in dna polymerase ii has been isolated from e. coli pola1 by mutagenesis with n-methyl-n'-nitro-n-nitrosoguanidine and assay of polymerase activity in extracts of survivors. the pola1 mutation was suppressed during mutagenesis by introduction of the suppressor, su7(+), into the parental strain. the mutant, hms83 pola1 polb1, contains less than 0.5% of the normal levels of dna polymerase ii. the only polymerase activity detected in the mutant is dna polymera ... | 1972 | 4559593 |
| bacteriophage t4 transformation: an assay for mutations induced in vitro. | 1972 | 4559688 | |
| ribosomes after t4-infection. | 1972 | 4560662 | |
| heterozygotes of three-factor crosses of bacteriophage t4. | 1972 | 4560676 | |
| an analysis of replication errors made by a defective t4 dna polymerase. | 1972 | 4560677 | |
| dna-directed synthesis in vitro of t4 phage-specific enzymes. | the synthesis of deoxynucleotide kinase (ec 2.7.4.2) in vitro by a preparation consisting of t4 bacteriophage dna and a cell-free extract of escherichia coli has been reported. a study of the role of monovalent cations in the synthesis of this enzyme as well as alpha-glucosyl transferase (ec 2.4.1.2) shows that potassium ions are required for maximal enzyme production. examination of the rna-directed system indicates that potassium ions are more effective than ammonium ion in the translation of ... | 1972 | 4560689 |
| in vitro complementation as an assay for new proteins required for bacteriophage t4 dna replication: purification of the complex specified by t4 genes 44 and 62. | we have developed an in vitro complementation assay for six t4 bacteriophage gene products believed to be components of the t4 dna replication apparatus. this assay is based upon the fact that dna synthesis in an infected cell lysate that lacks a given gene product is specifically stimulated by addition of the missing product. by the use of such an assay, two proteins that appear to be the products of t4 genes 44 and 62 have been purified to electrophoretic homogeneity as a single complex of the ... | 1972 | 4560698 |
| self-association of gene-32 protein of bacteriophage t4. | the self-association of gene-32 protein has been studied by sedimentation equilibrium centrifugation and polyacrylamide gel electrophoresis, in order to better understand its role in dna replication and genetic recombination. the monomer molecular weight of gene-32 protein is 38,000 in guanidine hydrochloride and 34,000 in sodium dodecyl sulfate, in agreement with the results of alberts and coworkers. stable dimers of gene-32 protein occur under various conditions, among which are high ionic str ... | 1972 | 4560700 |
| bacteriophage t4 transfer rna. i. isolation and characterization of two-phage-coded nonsense suppressors. | 1972 | 4560761 | |
| bacteriophage t4 head morphogenesis. iv. comparison of gene 16-, 17-, and 49-defective head structures. | defective heads present in extracts of bacteriophage t4 gene 16, 17, or 49 mutant-infected cells have been characterized. all appeared as empty shells when examined by negative-stain electron microscopy and showed essentially the same polypeptide pattern on sodium dodecyl sulfate-acrylamide gels. however, when analyzed by several other methods, gene 16- and 17-defective heads were shown to differ markedly from phage heads present in gene 49-defective extracts. first, the gene 16- and 17-defectiv ... | 1972 | 4561207 |
| evidence that more deoxynucleotide kinase mrna is transcribed than translated during t4 infection of escherichia coli. | 1972 | 4561233 | |
| initial step of excision repair in escherichia coli: replacement of defective function of uvr mutants by t4 endonuclease v. | 1972 | 4561346 | |
| role of the host cell in bacteriophage morphogenesis: effects of a bacterial mutation on t4 head assembly. | 1972 | 4561971 | |
| transcription of bacteriophage t4 dna by escherichia coli rna polymerase in vitro: identification of some immediate-early and delayed-early genes. | 1972 | 4562318 | |
| hybrid t4 r ii b cistrons created by genetic duplications. | 1972 | 4562710 | |
| transcription in yeast: a factor that stimulates yeast rna polymerases. | yeast cells contain an rna polymerase factor, pi, which is a heat-stable protein with an apparent molecular weight of 12,000. this factor stimulates transcription of calf-thymus, salmon-sperm, yeast-nuclear, and t4-phage dna. it stimulates transcription by each of the four yeast-nuclear rna polymerases, by rat-liver rna polymerases i and ii, and by escherichia coli rna polymerase. pi-factor can cause each of the eukaryotic rna polymerases to become insensitive to rifamycin af-013, but does not s ... | 1972 | 4562741 |
| rna synthesis in t4 infected escherichia coli during amino acid starvation. | 1972 | 4563040 | |
| mouse thymus-independent and thymus-derived lymphoid cells. ii. ultrastructural studies. | the ultrastructural features of b-, t-, and surface ig(sig)-bearing cells have been studied on cell suspensions from lymphoid organs of mice at different stages of immunization. the cells were identified by exposure to rabbit antibodies against mouse-specific lymphocyte antigens (msla) or brain-associated theta antigen (batheta) for t cells, mouse-specific bone marrow-derived lymphocyte antigens (mbla) for b cells, and mouse ig for sig-bearing cells. the rabbit antibodies fixed on the cell surfa ... | 1972 | 4563148 |
| role of genes 46 and 47 in bacteriophage t4 reproduction. ii. formation of gaps on parental dna of polynucleotide ligase defective mutants. | 1972 | 4563264 | |
| a bacteriophage t4 mutant defective in protection against superinfecting phage. | 1972 | 4563589 | |
| effect of bacteriophage ghost infection on protein synthesis in escherichia coli. | the rate of protein synthesis by escherichia coli markedly decreased within 1 min after phage t4 infection, whereas a complete cessation of protein synthesis was observed within at least 25 sec after t4 ghost infection. the cellular level of amino acids and aminoacyl-transfer ribonucleic acid (trna) did not change drastically upon infection with ghosts, indicating that the inhibition of protein synthesis took place at a step(s) beyond aminoacyl-trna formation. the host messenger rna remained int ... | 1972 | 4563594 |
| isolation and characterization of bacteriophage t4 base plates. | a method for isolating bacteriophage t4 base plates from lysates of escherichia coli b cells infected with the ts mutant in gene 19, ts b31 has been developed. by electrophoresis in polyacrylamide gel with sodium dodecyl sulfate the base plates have been shown to contain five to seven protein components with molecular weights of 36,000, 53,000, 66,000, 81,000, 87,000, and probably about 100,000. electron microscope studies have demonstrated that base plates may occur in two structural states: in ... | 1972 | 4563596 |
| defective concatemer formation in cells infected with deoxyribonucleic acid-delay mutants of bacteriophage t4. | nonpermissive host cells infected with phage t4 mutants in genes 52, 39, and 58 through 61 are shown to form short intracellular single-stranded deoxyribonucleic acid in contrast to wild-type infected cells, which form dimers and trimers of t4 genome size. | 1972 | 4563599 |
| exclusion of bacteriophages by t2 ghosts. | t2 ghosts do not exclude t4, t7, or lambda-induction in escherichia coli which survive ghost infection. latent periods are extended, probably by the temporary inhibition of protein synthesis. | 1972 | 4563601 |
| host cell deoxyribonucleic acid polymerase i and the support of t4 bacteriophage growth. | ultraviolet irradiation of escherichia coli pola(-) cells reduces their capacity to support the growth of t4 phage. there is no additional loss of capacity observed in pol tsa(-)reca(-) double mutants at the nonpermissive temperature. the reversion frequency of a t4 rii mutant after ultraviolet irradiation is not changed by the absence of host deoxyribonucleic acid polymerase i. | 1972 | 4563967 |
| e. coli dna polymerase i and other host functions participate in t4 dna replication and recombination. | 1972 | 4564186 | |
| in vivo production of an rna-dna copolymer after infection of escherichia coli by bacteriophage t4. | an rna-dna copolymer was isolated from escherichia coli infected with bacteriophage t4. the rna and dna are covalently linked, and in the same polynucleotide strand. the dna of the copolymer hybridizes specifically to the left strand of phage t4 dna. the copolymer is produced in cells infected with amber mutants of phage t4 deficient in dna replication and is not inhibited by the addition of chloramphenicol. | 1972 | 4564205 |
| a recombination gradient in bacteriophage t4 gene 34. | 1972 | 4564520 | |
| an rna polymerase mutant of escherichia coli defective in the t4 viral transcription program. | 1972 | 4564523 | |
| membrane protein synthesis after infection of escherichia coli b with phage t4: the riib protein. | 1972 | 4564529 | |
| on the direction of translation of the t4 deoxyribonucleic acid polymerase gene in vivo. | 1972 | 4564567 | |
| ribonucleotides covalently linked to deoxyribonucleic acid in t4 bacteriophage. | bacteriophage t4 was grown in the presence of labeled uridine. the deoxyribonucleic acid (dna) of the phage was shown to contain covalently attached ribonucleotides. the label appears not to be internal in the dna strands. presumably, it is at the ends of the dna strands and this may be related to dna initiation. | 1972 | 4564585 |
| association of replicative t4 deoxyribonucleic acid and bacterial membranes. | experiments utilizing cscl density gradient analysis and radioactive labels specific for bacteriophage t4 deoxyribonucleic acid (dna) and membranes have shown that replicative t4 dna is associated with host membranes. the association is inhibited by chloramphenicol and takes place just prior to semi-conservative replication of the phage dna. | 1972 | 4564586 |
| degradation of escherichia coli chromosome after infection by bacteriophage t4: role of bacteriophage gene d2a. | mutations in the d2a gene of bacteriophage t4 have recently been shown to result in the stabilization of cytosine-containing phage deoxyribonucleic acid (dna) made after infection by phage gene 56 (deoxycytidine triphosphatase) mutants. in the experiments reported here, we investigate the role of the d2a gene in the degradation of the host chromosome. we find that if t4 endonuclease ii, a product of the phage gene dena, is active, host chromosome degradation appears normal, regardless of the pre ... | 1972 | 4564588 |
| factors regulating triiodothyronine (t3) and thyroxine (t4) in blood. | 1972 | 4564709 | |
| studies on the biochemical basis of spontaneous mutation. i. a comparison of the deoxyribonucleic acid polymerases of mutator, antimutator, and wild type strains of bacteriophage t4. | 1972 | 4565077 | |
| ribonucleoside diphosphate reductase induced by bacteriophage t4. ii. allosteric regulation of substrate sepecificity and catalytic activity. | 1972 | 4565081 | |
| biochemistry of deoxyribonucleic acid-defective amber mutants of bacteriophage t4. 3. nucleotide pools. | 1972 | 4565086 | |
| specific inhibitors of ms2 and late t4 rna translation in e. coli. | 1972 | 4565492 |