Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| dietary polyunsaturated fat decreases interaction between low density lipoproteins and arterial proteoglycans. | polyunsaturated dietary fat (n-3 and n-6) results in less atherosclerosis in monkeys compared to lard (parks, j.s., kaduck-sawyer, j., bullock, b.c., and rudel, l.l., arteriosclerosis 10, 1102-1112; rudel, l.l., parks, j.s., johnson, f.l., and babiak, j., j. lipid res. 27, 465-474, 1986). we hypothesized that this was due, in part, to a decreased reactivity of low density lipoproteins (ldl) with arterial proteoglycans (pg). to test this hypothesis, cynomolgus monkeys were fed diets containing la ... | 1994 | 7815898 |
| effect of dietary linseed oil on tumoricidal activity and eicosanoid production in murine macrophages. | diets that contain high levels of n-3 fatty acids from fish oil have been shown to significantly effect macrophage cytolytic capacity, tumor necrosis factor alpha production and eicosanoid production. the present study was undertaken to determine whether n-3 fatty acids from vegetable origin [linseed oil (lin)] would have the same effects on murine macrophage tumoricidal capacity and eicosanoid production as would fish oil. mice were fed for three weeks diets that contained 10% (wt/wt) of either ... | 1994 | 7815900 |
| influence of korean pine (pinus koraiensis)-seed oil containing cis-5,cis-9,cis-12-octadecatrienoic acid on polyunsaturated fatty acid metabolism, eicosanoid production and blood pressure of rats. | the effects of dietary korean pine (pinus koraiensis)-seed oil containing a peculiar trienoic acid (cis-5,cis-9,cis-12-18:3, pinolenic acid, approximately 18%) on various lipid variables were compared in rats with those of flaxseed (linum usitatissimum l.) oil, safflower (carthamus tinctorius l.) oil and evening primrose (oenothera biennis l.) oil under experimental conditions where the effects of different polyunsaturated fatty acids could be estimated. in sprague-dawley rats fed on diets conta ... | 1994 | 7826999 |
| the effect of dietary lipid manipulation on rat lymphocyte subsets and proliferation. | polyunsaturated fatty acids (pufa) have been shown to suppress immune cell functions in vitro. dietary studies investigating the effects of pufa-containing oils on lymphocyte functions have yielded contradictory findings: such studies are difficult to compare as there are many variations in protocols. the present study investigated the effects of diets containing oils rich in saturated fatty acids, monounsaturated fatty acids, n-6 pufa or n-3 pufa on rat lymphocyte proliferation and on receptor ... | 1994 | 7835924 |
| the absorption and effect of dietary supplementation with omega-3 fatty acids on serum leukotriene b4 in patients with cystic fibrosis. | the substitution of omega-3 (n-3) fatty acids for omega-6 (n-6) fatty acids generates eicosanoids with diminished inflammatory effects. as the lungs of patients with cystic fibrosis (cf) are in a state of chronic inflammation in which increased amounts of eicosanoids are found, n-3 supplementation may reduce this level of inflammation and result in clinical improvement. the absorption and clinical effects of n-3 vs. n-6 fatty acids in cf were measured in a prospective, randomized, double-blind, ... | 1994 | 7838619 |
| [effect of xiaoyu pian on new platelet aggregation defect]. | the xiaoyu pian (xyp, mainly consisted of prunus persica, carthamus tinctorius, glycyrrhiza uralensis, etc) was used to treat patients with new platelet aggregation defect. patients were divided into 2 groups, the tcm group (72 cases) treated with xyp and the control group (65 cases) treated with vitamin c and p and/or adrenosem for at least 3 months. the results showed that marked effective rate was 87.5% in tcm group and 35.4% in control group (chi 2 = 39.7, p < 0.01); the recovery rate of pla ... | 1994 | 7719089 |
| diet-induced thermogenesis is lower in rats fed a lard diet than in those fed a high oleic acid safflower oil diet, a safflower oil diet or a linseed oil diet. | the objectives of the present study were to examine the effects of dietary fats differing in fatty acid composition on diet-induced thermogenesis, sympathetic activity in brown adipose tissue and body fat accumulation in rats. rats were meal-fed for 12 wk an isoenergetic diet based on lard, high oleic acid safflower oil, safflower oil or linseed oil, and norepinephrine turnover rates in brown adipose tissue were then estimated. whole-body oxygen consumption after the meal indicated that diet-ind ... | 1995 | 7722695 |
| dietary fatty acids and the glomerular hemodynamic response to cyclosporine in borderline hypertensive rats. | we have recently reported that cyclosporine a (csa) decreases glomerular filtration rate in the borderline hypertensive rat (bhr), but that the glomerular filtration rate is normal when the rats are maintained on a diet supplemented with evening primrose (ep) oil. the current studies were designed to determine the glomerular hemodynamic changes responsible for this effect. a first group (plac-saff) received a diet supplemented with safflower oil (saff) (10% of calories) and placebo (plac). a sec ... | 1995 | 7723248 |
| high fat diet-induced hyperglycemia: prevention by low level expression of a glucose transporter (glut4) minigene in transgenic mice. | high-fat intake leading to obesity contributes to the development of non-insulin-dependent diabetes mellitus (niddm, type 2). similarly, mice fed a high-fat (safflower oil) diet develop defective glycemic control, hyperglycemia, and obesity. to assess the effect of a modest increase in the expression of glut4 (the insulin-responsive glucose transporter) on impaired glycemic control caused by fat feeding, transgenic mice harboring a glut4 minigene were fed a high-fat diet. low-level tissue-specif ... | 1995 | 7724522 |
| influence of cell culture conditions on diet-induced changes in lymphocyte fatty acid composition. | the effect of a range of dietary lipids on the fatty acid composition and membrane fluidity of lymphocytes was investigated. the effects of subsequent culture of these lymphocytes in medium containing autologous serum, foetal calf serum or a serum-free supplement were assessed; this was considered important, since many studies investigating the effects of dietary lipid manipulation on immune function have used protocols involving a variety of cell culture conditions when performing tests of immu ... | 1995 | 7734450 |
| differential fatty acid accretion in heart, liver and adipose tissues of rats fed beef tallow, fish oil, olive oil and safflower oils at three levels of energy intake. | to examine interactive effects of dietary fatty acid composition and energy restriction on tissue fatty acid accretion, mature rats consumed diets containing beef tallow, fish oil, olive oil or safflower oil with free access or at 85% or 68% of free access energy intakes. restriction was accomplished by adjustment of dietary carbohydrate level. after 10 wk, animals were killed, and the fatty acid compositions of liver, heart and adipose tissues were examined. compared with animals given free acc ... | 1995 | 7738677 |
| nutritional modulation of guinea pig skin hyperproliferation by essential fatty acid deficiency is associated with selective down regulation of protein kinase c-beta. | in a previous study we demonstrated that 13-hydroxyoctadecadienoic acid (13-hode), a 15-lipoxygenase metabolite of linoleic acid is incorporated into epidermal phosphatidyl 4,5-bisphosphate (ptdins 4,5-p2) and released as 13-hode-containing-diacylglycerol (13-hode-dag). in vitro, 13-hode-dag was shown to selectively inhibit epidermal total protein kinase c (pkc-beta) activity. to determine whether these observations are relevant in vivo, guinea pigs were made essential fatty acid deficient (efad ... | 1995 | 7472653 |
| effects of chemical sympathectomy on lipoprotein lipase activities in peripheral tissues of rats fed high fat diets consisting of different fats. | we have previously reported that the feeding of a beef tallow diet gives lower lipoprotein lipase activities in the interscapuler brown adipose tissue, heart and soleus muscle compared with feeding of a safflower oil diet. we have also suggested that sympathetic activities (norepinephrine turnover rates and beta-adrenergic receptor bindings) in these peripheral tissues were lower in the beef tallow diet group. to confirm the effects of dietary fats on the lipoprotein lipase activities in these t ... | 1995 | 7472681 |
| beef tallow diet decreases beta-adrenergic receptor binding and lipolytic activities in different adipose tissues of rat. | the effects of dietary fats consisting of different fatty acids on lipolytic activity and body fat accumulation were studied in rats. sprague-dawley male rats were meal-fed an isoenergetic diet based on either beef tallow or safflower oil for 8 weeks. lipolytic activities in epididymal and subcutaneous adipose tissues were lower in the beef tallow diet group than in the safflower oil diet group. body fat accumulation was greater in rats fed the beef tallow diet versus the safflower oil diet. nor ... | 1995 | 7476283 |
| beef tallow diet decreases norepinephrine turnover rates in rat hypothalamus and cerebral cortex. | the effects of dietary fats consisting of different fatty acids on norepinephrine (ne) turnover rates in various brain regions were studied in rats. sprague-dawley male rats were meal-fed isoenergetic diets based on safflower oil or beef tallow for 8 weeks. body weight gain during the experimental period did not differ between the two groups of rats. the weights of brain regions were also similar in the two diet groups. basal ne contents and turnover rates in the hypothalamus and cortex were sig ... | 1995 | 7476320 |
| alteration of the fiber and lipid components of a defined-formula diet: effects on stool characteristics, nutrient digestibility, mineral balance, and energy metabolism in humans. | eighteen healthy males with a body weight of 70.0 +/- 3.1 kg consumed three defined-formula diets that varied only in their fiber and/or lipid components: 1) 6.4% fiber (100% soy polysaccharides) and 13.1% lipid [50% medium-chain triacylglycerols (mcts), 40% corn oil, and 10% soy oil]; 2) 3.4% fiber (75% oat fiber, 17.5% gum arabic, and 7.5% carboxymethylcellulose) and 15.6% lipid (20% mcts, 50% canola oil, and 30% high oleic acid safflower oil); and 3) 4.4% fiber (same as diet 2) and 14.5% lipi ... | 1995 | 7491889 |
| effect of a high alpha-linolenate and high linoleate diet on membrane-associated enzyme activities in rat brain--modulation of na+, k+- atpase activity at suboptimal concentrations of atp. | semi-purified diets supplemented with either a high alpha-linolenate (n - 3) (perilla) oil or a high linoleate (n - 6) (safflower) oil were fed to rats through two generations. rats fed safflower oil showed a decrease in docosahexaenoic acid (n - 3) and a compensatory increase in docosapentaenoic acid (n - 6) in all the brain regions and organelles examined, when compared with rats fed perilla oil. as reported previously, the safflower oil-fed rats exhibited inferior learning ability compared wi ... | 1995 | 7492979 |
| nutrition and allorejection impact of lipids. | polyene n-3 and n-6 fatty acids are claimed to have immunomodulating properties. the impact of nutritional variations on transplant rejection was therefore studied in the heterotopic rat heart allotransplant model with particular focus on lipids. twenty per cent fat emulsions with differing n-3/n-6 fatty acid ratios were continuously infused (9 g fat per kg bodyweight per day; n = 10 in each group) after transplantation until rejection: safflower oil (n-3/n-6 = 1/370), fish oil (7.6/1), soybean ... | 1995 | 7551981 |
| effects of dietary alpha- and gamma-linolenic acids on liver fatty acids, lipid metabolism, and survival in sepsis. | the effects of dietary treatment for 3 weeks with soybean oil, linseed- and safflower oil (high alpha-linolenic acid, ala), or borage oil (high gamma-linolenic acid, gla) on the liver fatty acid profile and lipid metabolism in fed rats, in normal fasted rats, and septic fasted rats, and on survival from sepsis, were studied. the results were the following: 1) dietary ala increased incorporation of alpha-linolenic (18:3w3), eicosapentaenoic (20:5w3), and docosapentaenoic (22:5w3) acids in neutral ... | 1995 | 7552772 |
| regulation of rat liver apolipoprotein a-i, apolipoprotein a-ii and acyl-coenzyme a oxidase gene expression by fibrates and dietary fatty acids. | the regulation by fibrates and dietary fatty acids of the hepatic gene expression of apolipoproteins (apo) a-i and a-ii, the major protein constituents of high-density lipoproteins, as well as of acyl-coa oxidase, the rate-limiting enzyme of the peroxisomal beta-oxidation pathway, was studied in vivo in the rat and in vitro in primary cultures of rat hepatocytes. in primary hepatocytes, different fibrates decreased apo a-i and increased acyl-coa oxidase mrna levels, whereas apo a-ii mrna only de ... | 1995 | 7556148 |
| dietary fatty acids, membrane transport, and oxidative sensitivity in human erythrocytes. | this study examined effects of dietary n-3 fatty acids on age-related changes in erythrocyte anion transport and susceptibility to oxidation. blood was drawn from healthy adult volunteers before and after six weeks' supplementation (nine/group) with 4.0 g/day of safflower oil (containing 2.9 g n-6 fatty acids) or fish oil (containing 1.2 g long-chain n-3 fatty acids). following density separation of young and old erythrocytes, membrane anion transport and cell membrane lipid composition were mea ... | 1995 | 7564921 |
| the effect of dietary polyunsaturated fatty acids (pufa) on acute rejection and cardiac allograft blood flow in rats. | for six weeks, recipient (lewis rt11) and donor rats (lbnf11/n) were fed three diets that varied only in their lipid content. diet a (mo) contained 19.5% menhaden oil and 0.5% safflower oil and was rich in omega 3 pufa; diet b (so) was 20% safflower oil rich in omega 6 pufa; and diet c (bt) was 20% beef tallow rich in omega 9 monounsaturated fatty acids and saturated fat. in the first set of graft survival studies a group fed laboratory chow was included (chow). heterotopic cardiac transplantati ... | 1995 | 7570953 |
| effects of n-3 and n-6 polyunsaturated fatty acid-enriched diets on lipid metabolism in periportal and pericentral compartments of female rat liver lobules and the consequences for cell proliferation after partial hepatectomy. | the effects of a low fat diet or diets enriched with either n-6 or n-3 polyunsaturated fatty acids (safflower or fish oil, respectively) on lipid metabolism in periportal and pericentral zones of female rat liver lobules were investigated in relation with cell proliferation after partial hepatectomy. it was found that cell proliferation was localized almost exclusively in periportal and midzonal areas and was significantly reduced by 60% after a fish oil diet only. the fish oil diet caused a str ... | 1995 | 7595092 |
| effects of coconut oil, butter, and safflower oil on lipids and lipoproteins in persons with moderately elevated cholesterol levels. | the physiological effects of coconut oil, butter, and safflower oil on lipids and lipoproteins have been compared in moderately hypercholesterolemic individuals. twenty eight participants (13 men, 15 women) followed three 6-week experimental diets of similar macronutrient distribution with the different test fats providing 50% total dietary fat. total cholesterol and low density lipoprotein cholesterol were significantly higher (p < 0.001) on the diet containing butter [6.8 +/- 0.9, 4.5 +/- 0.8 ... | 1995 | 7595099 |
| alpha-linolenic acid in the treatment of rheumatoid arthritis. a double-blind, placebo-controlled and randomized study: flaxseed vs. safflower seed. | in rheumatoid arthritis various pro-inflammatory metabolites of arachidonic acid (aa), such as leukotriene b4 (ltb4) and prostaglandin e2 (pge2), contribute to tissue destruction and pain. in contrast to aa, which is an omega-6 fatty acid, the omega-3 fatty acids, after having been liberated from the cell membrane phospholipids, are further converted into the non- or anti-inflammatory eicosanoids ltb5 and pgi3. aa concentration is an important regulatory step in the synthesis of both prostanoids ... | 1995 | 7597378 |
| dietary fat alters the distribution of cholesterol between vesicles and micelles in hamster bile. | the type of dietary fat strongly affects the incidence of gallstones in the hamster model of cholesterol cholelithiasis. the present study was designed to determine whether dietary fats could affect gallstone formation by altering the microstructure (vesicular/micellar ratio) of cholesterol in bile. golden syrian hamsters from sasco (omaha, ne) or charles river (wilmington, ma) were fed nutritionally adequate semipurified diets to which were added: (i) 4.0% butterfat without added cholesterol; ( ... | 1995 | 7609596 |
| sympathetic activity is lower in rats fed a beef tallow diet than in rats fed a safflower oil diet. | effects of dietary fats consisting of different fatty acids on sympathetic activity and body fat accumulation were studied in rats. rats were meal-fed an isoenergetic diet based on either beef tallow or safflower oil for 8 weeks. carcass fat content was greater (p < .05) in rats fed the beef tallow diet than in rats fed the safflower oil diet. norepinephrine (ne) turnover rate was significantly lower (p < .05) in interscapular brown adipose tissue (ibat) and pancreas in rats fed the beef tallow ... | 1995 | 7616854 |
| dietary fats rich in saturated fatty acids (12:0, 14:0, and 16:0) enhance gallstone formation relative to monounsaturated fat (18:1) in cholesterol-fed hamsters. | to test the possibility that dietary palmitic acid (16:0) may be lithogenic, different fats were blended to exchange 18:1 in olive oil with either 16:0 in palm stearin, 12:0 + 14:0 in coconut oil, or 14:0 + 16:0 in butterfat. dietary 18:2 was held constant at 1.2% energy (en) (with extra safflower oil as needed) in these four purified diets containing low fat (11% of total energy) and 0.4% cholesterol. a fifth, high-fat diet provided 40% of the total energy as the 16:0-rich blend. all hamsters f ... | 1995 | 7637561 |
| dietary manipulation of long-chain polyunsaturated fatty acids in the retina and brain of guinea pigs. | high levels of n-6 docosapentaenoic acid (22:5n-6) have been reported in the retina of guinea pigs fed commercially-prepared gain-based rations (commercial diet). in rats and monkeys, high levels of 22:5n-6 are an indicator of n-3 polyunsaturated fatty acid (pufa) deficiency. we have examined the fatty acid composition of the retina and brain in guinea pigs fed a commercial diet or one of three semi-purified diets containing three different levels of n-3 pufa. the diets comprised a diet deficien ... | 1995 | 7637569 |
| [study on economic npk(nitrogen-phosphorus-potassium)-requirements for medicinal safflower]. | a design of second order orthogonal rotative regression was developed and field tested, and a model for obtaining 18kg/mu dry flower yield was simulated and built according to several better combinations based on the model of total safflower dry flower yield. the optimal npk-requirements for obtaining the above 18kg/mu dry flower yield are n:6-6.5kg/mu, p2o5:10.0-11.0kg/mu, k2o:6.9-10.0kg/mu. these requirements may be adjusted rationally according to soil fertility, manure sources, and so on. | 1995 | 7646774 |
| [stimulating action of carthamus tinctorius l., angelica sinensis (oliv.) diels and leonurus sibiricus l. on the uterus]. | the experimental results indicate that the decoction of chinese drugs carthamus tinctorius, angelica sinensis and leonurus sibiricus has stimulating action on the uterus of mouse in vitro. the stimulating action of carthamus tinctorius and leomurus sibiricus has been found related to stimulating h1-receptor and alpha-adrenergic receptor of uterus, but the action of angelica sinensis to stimulating h1-receptor of uterus only. | 1995 | 7646782 |
| low density lipoprotein binding to monolayer cultures of hepatocytes isolated from hamsters fed different dietary fatty acids. | (i) the aim of these studies was to investigate the effect of dietary cholesterol and dietary fat on the expression of the hepatic low density lipoprotein (ldl) receptor. (ii) low density lipoprotein (ldl) binding to monolayer cultures of hepatocytes isolated from hamsters fed different amounts of cholesterol and fats was measured. (iii) hepatocytes isolated from hamsters fed a low cholesterol diet (< 0.008% w/w) specifically bound ldl and this binding increased with time in culture. by comparis ... | 1995 | 7654782 |
| dietary high-linoleate safflower oil is not hypocholesterolemic in aged mice after a long-term feeding--comparison with lard, perilla oil and fish oil. | aged mice (6 months of age) fed a conventional diet were shifted to diets containing 10% lard, high-linoleate safflower seed oil, high alpha-linolenate perilla seed oil or high-docosahexaenoate fish oil. a significant increase in whole body cholesterol (/g wt) was seen within 30 d after the shift (rapid response), followed by a gradual decrease in 60 to 120 d (slow response); similar changes occurred in all the dietary groups. shortly after the shift, the serum cholesterol concentrations increas ... | 1995 | 7655414 |
| effects of dietary lipid manipulation upon graft vs host and host vs graft responses in the rat. | the popliteal lymph node (pln) assay was used to establish whether dietary lipids with differing fatty acid compositions could affect cell-mediated immunity in the rat. weanling rats were fed for 4 weeks on a lowfat (2.5% by weight; lf) diet or on diets containing 20% (by weight) hydrogenated coconut oil (hco), olive oil (oo), safflower oil (so), evening primrose oil (epo), or menhaden (fish) oil (mo). feeding the mo diet suppressed the graft vs host response compared with feeding the lf, hco, s ... | 1995 | 7656333 |
| marine and freshwater fish oil varying in arachidonic, eicosapentaenoic and docosahexaenoic acids differ in their effects on organ lipids and fatty acids in growing rats. | arachidonic acid [20:4(n-6)] and docosahexaenoic acid [22:6(n-3)] are important to normal neurodevelopment and visual function. infants fed formula often have low blood lipid 20:4(n-6) and 22:6(n-3). consumption of fish oils high in eicosapentaenoic acid [20:5(n-3)] and 22:6(n-3) with no 20:4(n-6) increases tissue 20:5(n-3) and 22:6(n-3) but decreases 20:4(n-6). some freshwater fish oils contain higher 20:4(n-6) and lower 20:5(n-3) than usual marine fish oils, but their effects on tissue fatty a ... | 1995 | 7666244 |
| serum triiodothyronine concentration and na+,k(+)-atpase activity in liver and skeletal muscle are influenced by dietary fat type in rats. | it has been shown previously that dietary fat type influences body fat accumulation in rats. the effects of dietary fat type on serum thyroid hormone, activity of na+,k(+)-atpase and lipoprotein lipase were studied. rats were fed an experimental diet containing lard, high oleic safflower oil, safflower oil or linseed oil for 12 wk. carcass fat content was significantly higher in rats fed the lard diet than in those fed the other diets. however, intra-abdominal adipose tissue weights were not aff ... | 1995 | 7666254 |
| preparation of radioactively labeled synthetic sn-1,2-diacylglycerols for studies of lipid metabolism. | a method was developed for the synthesis of stereo-specific sn-1,2-diacylglycerols radioactively labeled on the glycerol backbone. this method includes the acylation of l-[u-14c]glycerol 3-phosphate with fatty acid anhydrides in the presence of dimethylaminopyridine and the tetraethylammonium salt of the fatty acid used for the acylation. the phosphatidic acid obtained from this synthesis was converted to sn-1,2-diacyl[u-14c]glycerol by the action of phospholipase c. when di10:0-, di-18:1-, di-1 ... | 1995 | 7710117 |
| dietary alpha-linolenate/linoleate balance influences learning and memory in the senescence-accelerated mouse (sam). | the senescence-accelerated mouse (samp8) is a model of age-related deterioration of memory and learning ability. a semipurified diet supplemented either with safflower oil (rich in linoleate) or with perilla oil (rich in alpha-linolenate) was fed to samp8 mouse dams and their pups. the offspring (males from several mothers) at 28 weeks of age were used for behavioral tests. the proportions of n-3 and n-6 highly unsaturated fatty acids in brain phospholipids reflected the n-3/n-6 balance of the d ... | 1995 | 7712178 |
| cloning and expression in escherichia coli of a novel thioesterase from arabidopsis thaliana specific for long-chain acyl-acyl carrier proteins. | an arabidopsis thaliana partial cdna was previously identified with a sequence similar to the lauroyl-acyl carrier protein (acp) thioesterase from umbellularia california (grellet et al., 1993, plant physiol. biochem. 31, 599-602). using this dna fragment, we isolated a 1.8-kb cdna coding for a 412-amino-acid preprotein. the deduced amino acid sequence is 51% identical to the lauroyl-acp thioesterase but only 39% identical to safflower oleoyl-acp thioesterase. the cdna was expressed in escherich ... | 1995 | 7840673 |
| effects of dietary lipid manipulation upon inflammatory mediator production by murine macrophages. | this study investigated the effects of feeding mice lipids with different fatty acid compositions upon the ability of stimulated macrophages to produce inflammatory mediators. weanling mice were fed for 8 weeks on a low-fat (lf; 2.5% by weight) diet or on diets containing 20% by weight of hydrogenated coconut oil (hco), olive oil (oo), safflower oil (so), or menhaden (fish) oil (mo). thioglycollate-elicited peritoneal macrophages were isolated. macrophages isolated from mo-fed mice produced less ... | 1995 | 7758122 |
| zinc deficiency and activities of lipogenic and glycolytic enzymes in liver of rats fed coconut oil or linseed oil. | in previous studies, zinc-deficient rats force-fed a diet with coconut oil as the major dietary fat developed a fatty liver, whereas zinc-deficient rats force-fed a diet with linseed oil did not. the present study was conducted to elucidate the reason for this phenomenon. in a bifactorial experiment, rats were fed zinc-adequate or zinc-deficient diets containing either a mixture of coconut oil (70 g/kg) and safflower oil (10 g/kg) ("coconut oil diet") or linseed oil (80 g/kg) ("linseed oil diet" ... | 1995 | 7760690 |
| comparison of the effects of a range of dietary lipids upon serum and tissue lipid composition in the rat. | since the type of fat consumed in the diet may play a role in the development of several disorders, it is important to ascertain the effects of different dietary fats upon parameters such as serum lipid levels and adipose deposition. the aim of this study was to determine the effects of feeding rats a range of fats with differing fatty acid compositions. weanling male rats were fed for 10 weeks on a low fat (lf) diet or on one of five high fat diets, which contained 20% by weight of either hydro ... | 1995 | 7780834 |
| muscle respiration in rats is influenced by the type and level of dietary fat. | experiments were conducted to elucidate the role of muscle in the enhanced thermogenic response found in rats fed diets enriched with polyunsaturated fatty acids. isolated soleus muscle respiration and plasma cholesterol and triglyceride concentrations were determined in rats (approximately 128 g wt, 5 wk age) fed diets (minimum 3 wk) containing coconut oil, beef tallow or safflower oil at 20, 40 or 60% of the total dietary energy in a 3 x 3 factorial design (5-6 rats per treatment). diet type d ... | 1995 | 7782909 |
| modulation of signal transduction in macrophages by dietary fatty acids. | tumor growth can be altered by the amount and type of fat in the diet. although there are several possible mechanisms for this, recent work suggests that alterations in the immune system by dietary fat may affect tumorigenesis. the focus of recent studies has been on dietary fat modulation of macrophage function because that cell plays a pivotal role in many immune responses, including anti-tumor activity. one possible mechanism of dietary fat effects on macrophages is altered signal transductio ... | 1995 | 7782926 |
| [immunosuppressive effect of parenteral fat emulsions in defined immunostimulation]. | in the heterotopic rat heart allotransplant model we have previously shown that intravenous fat emulsions are to a various extent immunosuppressive or immunoneutral, dependent on their n-3/n-6 fatty acid ratio. safflower oil (n-3: n-6 = 1:370), fish oil (7.6:1) and soybean oil (1:6.5) prolonged the transplant survival time to 13.3, 12.3 and 10.4 days compared to 6.7 days (oil control group; 1.2.1) and 7.8 days (saline control group) (p < 0.01), respectively. this study presents a correlation of ... | 1995 | 7787404 |
| effect of dietary fat and environmental lighting on the phospholipid molecular species of rat photoreceptor membranes. | we have previously shown that retinas of albino rats adapt to bright cyclic light (500-800 lx) by lowering the levels of docosahexaenoic acid (22:6n-3) in their rod outer segment (ros) phospholipids. in the present study, we addressed the role of dietary fat in this process. pregnant rats were kept in 1 lx or 250 lx cyclic illuminance (12l:12d) and fed diets containing 10% (by weight) of either hydrogenated coconut oil (coc, no n-3 or n-6 fatty acids), linseed oil (lin, n-3 and n-6 fatty acids), ... | 1995 | 7789409 |
| effect of dietary fat on the response of the rat retina to chronic and acute light stress. | we designed an experiment to study the role of light history and polyunsaturated fatty acids (pufa) on the susceptibility of the albino rat retina to light damage. albino rats were born to dams that had been kept in either 1 lx or 250 lx cyclic light for 0-4 days prior to delivery and fed one of three diets containing either 10% (by weight) hydrogenated coconut oil (coc, no n-3 nor n-6 fatty acids), safflower oil (saf, high n-6, < 0.1% n-3 fatty acids), or linseed oil (lin, high n-3, low n-6 fat ... | 1995 | 7789410 |
| differential effects of high-fat diets varying in fatty acid composition on the efficiency of lean and fat tissue deposition during weight recovery after low food intake. | the energetics of body weight recovery after low food intake was examined in the rat during refeeding for 2 weeks with isocaloric amounts of high-fat (hf) diets providing 50% of energy as either lard, coconut oil, olive oil, safflower oil, menhaden fish oil, or a mixture of all these fat types. the results indicate that for both body fat and protein, the efficiency of deposition was dependent on the dietary fat type. the most striking differences were found (1) between diets rich in n-3 and n-6 ... | 1995 | 7869927 |
| effects of randomization of partially hydrogenated corn oil on fatty acid and cholesterol absorption, and tissue lipid levels in rats. | randomization of partially hydrogenated corn oil containing approximately 45% of trans octadecenoic acid only slightly, but not significantly, increased the lymphatic fatty acid absorption in rats. no effect of randomization was observed on cholesterol absorption. when rats were fed these fats at the 8.8% level (with 1.2% safflower oil) for three weeks, the concentrations of serum cholesterol, and serum and liver phospholipid were significantly higher in randomized fat than in control fat, which ... | 1995 | 8538381 |
| prevention of experimental autoimmune encephalomyelitis in lewis rats by a novel fungal source of gamma-linolenic acid. | the effects of oral administration of linoleic- and gamma-linolenic-acid-rich oils on the clinical and histopathological manifestations of experimental autoimmune encephalomyelitis (eae) were investigated in lewis rats 7 d post-inoculation. gamma-linolenic-acid-rich fungal (mucor javanicus) oil at 500 mg/kg body weight abrogated clinical and histological signs of eae although at doses of 200 and 1000 mg/kg body weight it was only effective in delaying the onset of clinical disease. linoleic-acid ... | 1995 | 8541276 |
| therapeutic efficacy of n-3 polyunsaturated fatty acid in experimental crohn's disease. | we investigated the therapeutic efficacy of n-3 polyunsaturated fatty acids (pufas) on trinitro-benzene sulfonic acid (tnbs)-induced colitis in the rats, which condition is considered an experimental crohn's disease (cd). in rats with tnbs-induced colitis, feeding with an elemental diet (ed) plus 2% n-3 puea-rich perilla oil significantly suppressed plasma leukotriene (lt) b4 and ulcer index compared to that in rats fed with ed plus 2% n-6 pufa-rich safflower oil (34.2 +/- 12.3 s 63.8 +/- 13.2 p ... | 1995 | 8563904 |
| effect of dosing vehicle on the toxicity and metabolism of unsaturated aliphatic nitriles. | the effect of dosing vehicle on toxicity and metabolism of unsaturated aliphatic nitriles was investigated in male sprague-dawley rats. five unsaturated aliphatic nitriles--acrylonitrile, methacrylonitrile, allylnitrile, crotononitrile and fumaronitrile--were prepared in five different dosing vehicles--saline, corn oil, safflower oil, mineral oil, olive oil and tween-20. groups of six male rats were given 0.5 ld50 doses of the nitriles by gavage and they were observed for 12 it for cholinomimeti ... | 1995 | 8666726 |
| chemiluminescence detection of mono-, bis-, and tris-hydroperoxy triacylglycerols present in vegetable oils. | a reliable method was needed to analyze molecular species of oxidized vegetable oils. in order to accomplish this goal, mono-, bis-, and tris-hydroperoxides (mono-ooh, bis-ooh, and tris-ooh, respectively) of triacylglycerols formed during autoxidation and photosensitized oxidation of oils were determined by reversed-phase high-performance liquid chromatography in combination with chemiluminescence detection (cl-hplc). mono-ooh was the major species (96% of total hydroperoxides) in trioleoylglyce ... | 1995 | 8569427 |
| protective effect of coconut oil on renal necrosis occurring in rats fed a methyl-deficient diet. | weanling rats fed a methyl-deficient diet develop renal necrosis with acute renal failure. the aim of this experiment was to explore further the role of coconut oil in this experimental model. weanling wistar male rats were fed methyl-deficient and their controls were fed methyl-supplemented diets. coconut oil was fed at 14% and 20%, the latter concentration with and without 1% safflower oil (rich in linoleic acid); other groups received similar diets but instead of coconut oil, a mixture of hyd ... | 1995 | 8570865 |
| the impact of dietary fats, photoperiod, temperature and season on morphological variables, torpor patterns, and brown adipose tissue fatty acid composition of hamsters, phodopus sungorus. | we investigated how dietary fats and oils of different fatty acid composition influence the seasonal change of body mass, fur colour, testes size and torpor in djungarian hamsters, phodopus sungorus, maintained from autumn to winter under different photoperiods and temperature regimes. dietary fatty acids influenced the occurrence of spontaneous torpor (food and water ad libitum) in p. sungorus maintained at 18 degrees c under natural and artificial short photoperiods. torpor was most pronounced ... | 1995 | 8576453 |
| olive oil, other dietary fats, and the risk of breast cancer (italy). | data from a multicenter case-control study on breast cancer conducted in italy have been used to analyze the relationship of olive oil and other dietary fats to breast cancer risk. cases were 2,564 women hospitalized with histologically confirmed, incident breast cancer. controls were 2,588 women admitted to the same network of hospitals for acute, non-neoplastic, non-hormone related, non-digestive tract disorders. cases and controls were interviewed between 1991 and 1994 using a validated food- ... | 1995 | 8580304 |
| the effects of dietary lipid manipulation on the production of murine t cell-derived cytokines. | lymphocytes play an important part in the development and progression of a number of autoimmune and inflammatory disorders, which are characterized by the presence of activated t cells and cytokines at the site of tissue injury and in the circulation. there has been considerable interest in using dietary polyunsaturated fatty acids (pufa), particularly the n-3 pufa found in fish oils, in the therapy of these conditions; such therapies aim, primarily, to suppress t-lymphocyte activity. while seve ... | 1995 | 8580371 |
| effect of fish oil on the development of aom-induced glutathione s-transferase placental form positive hepatocellular foci in male f344 rats. | omega-3 fatty acids, which are contained in fish oils and certain vegetable oils in contrast to corn oil or safflower oil rich in omega-6 fatty acids (linoteic acid), have been reported to reduce the carcinogenesis in several organs. in this study, the modifying effect of menhaden fish oil was investigated on the occurrence of azoxymethane (aom)-induced glutathione s-transferase placental form (gst-p) positive hepatocellular foci, recognized preneoplastic lesions in the liver, in male f344 rats. ... | 1995 | 8584454 |
| effect of n-3 polyunsaturated fatty acid supplemented diet on neutrophil-mediated ileal permeability and neutrophil function in the rat. | fish oil, rich in n-3 polyunsaturated fatty acids, can alter leukotriene production and hence neutrophil function, factors which may be important in the inflammation of crohn's disease (cd). therefore we studied the effect of dietary pufa on neutrophil mediated ileal inflammation and neutrophil function in the rat. | 1995 | 8586775 |
| fish oil ameliorates renal injury and hyperlipidemia in the milan normotensive rat model of focal glomerulosclerosis. | rats of the milan normotensive rat strain (mns) spontaneously develop severe proteinuria and excessive glomerular thromboxane (tx)a2 production at a young age. these abnormalities are accompanied by podocyte alterations, progressive focal glomerulosclerosis (fgs), and interstitial fibrosis, resembling human fgs. since it has been shown that pharmacologic tx-synthase inhibition protects mns rats from these changes, it was hypothesized that a fish oil (fo) enriched diet, by enhancing txa3 producti ... | 1995 | 8589325 |
| effects on reproduction in female offspring from sprague-dawley rats fed 10% snakeweed (gutierrezia microcephala) throughout pregnancy and concurrent treatment with safflower oil. | previous studies determined that safflower oil administration provided protection against the embryotoxicity seen following ingestion of 10% snakeweed (gutierrezia microcephala) throughout pregnancy. sixty-two young primiparous female rats born in those studies were paired with adult male sprague-dawley rats. after 4 d they were removed and carried their litters to term. observations were made of the presence and extent of reproductive effects attributable to the 10% snakeweed exposure and diffe ... | 1995 | 8592831 |
| influence of an n-6 polyunsaturated fatty acid-enriched diet on the development of tolerance during chronic ethanol administration in rats. | this study investigates the effects of n-6 polyunsaturated fatty acids (pufas), in the form of dietary evening primrose oil (epo) and safflower oil, on the development of tolerance to ethanol. the degree of fluorescence polarization of the fluoroprobes dph, prop-dph, and tma-dph in isolated cortical synaptosomal membranes was measured. in addition, the development of tolerance, as shown by changes in synaptosomal membrane fluidity after an acute in vitro ethanol challenge, was also determined af ... | 1995 | 8749808 |
| effect of dietary soybean phospholipid and fats differing in the degree of unsaturation on fatty acid synthesis and oxidation in rat liver. | the activities of enzymes in fatty acid oxidation and synthesis in the liver of rats fed soybean phospholipids and soybean oil corresponding to the dietary levels of 3% fatty acid added to the diets containing a saturated fat (coconut oil) and a polyunsaturated fat (safflower oil) at the amounts corresponding to 12% fatty acid levels were compared. soybean phospholipid compared with soybean oil added to both coconut and safflower oil diets significantly reduced the activities of enzymes in fatty ... | 1995 | 8926536 |
| diets high in polyunsaturated oils decrease lymphocyte membrane anisotropy and b-cell mitogenesis. | balb/c mice were fed semipurified diets containing 40% of total calories as lipids: olive, safflower, or fish oil. after 2 weeks of feeding, splenic mononuclear cells were isolated and assayed for steady-state fluorescence anisotropy by means of the probe diphenylhexatriene. splenocytes were also incubated with the mitogens concanavalin a, phytohemagglutinin, or lipopolysaccharide; subsequent uptake of tritiated thymidine was measured as an index of proliferation. no differences were observed in ... | 1995 | 8719135 |
| activities of liver microsomal fatty acid desaturases in zinc-deficient rats force-fed diets with a coconut oil/safflower oil mixture of linseed oil. | the present study was conducted to investigate the effect of zinc deficiency on fatty acid desaturation in rats fed two different types of dietary fat, a mixture of coconut oil and safflower oil (7:1, w/w, "coconut oil diet") or linseed oil ("linseed oil diet"). in order to ensure an adequate food intake, all rats were force-fed by gastric tube. zinc deficiency caused statistical significant reduction of delta 9-desaturase activity in liver microsomes of rats fed coconut oil diet and tendencial ... | 1995 | 9398942 |
| microbiology of siljo, a traditional ethiopian fermented legume product. | siljo was prepared by thoroughly cooking powdered horsebean (vicia faba) in safflower (carthamus tinctorius) extract into a semi-solid slurry and then adding to it untreated black mustard (brassica nigra) powder after cooling to 50°c. the black mustard powder was the source of starter microorganisms, with lactobacillus acidophilus, l. plantarum and l. delbruekii initiating and later dominating the fermentation process. the ph of the fermenting mass dropped to 4.5 within 36 h and reached 4.0 at 1 ... | 1995 | 24414662 |
| improvements in rooting regenerated safflower (carthamus tinctorius l.) shoots. | a continuing obstacle for regenerating safflower (carthamus tinctorius l.) plants from cultured explants or callus has been a reliable method for rooting shoots. for shoots directly regenerated from primary explants, 76% of shoots rooted after a 7-d exposure to 10 mg/1 indole-3-butyric acid. auxin source, concentration or exposure time did not greatly affect root formation or morphology, but strongly affected callus production. shoots infected with agrobacterium rhizogenes produced massive numbe ... | 1996 | 24178666 |
| regulation of population densities of heterodera cajani and other plant-parasitic nematodes by crop rotations on vertisols, in semi-arid tropical production systems in india. | the significance of double crop (intercrop and sequential crop), single crop (rainy season crop fallow from june to september), and rotations on densities of heterodera cajani, helicotylenchus retusus, and rotylenchulus reniformis was studied on vertisol (typic pellusterts) between 1987 and 1993. cowpea (vigna sinensis), mungbean (phaseolus aureus), and pigeonpea (cajanus cajan) greatly increased the population densities of h. cajani and suppressed the population densities of other plant-parasit ... | 1996 | 19277141 |
| effects of fat emulsions with different fatty acid composition on plasma and hepatic lipids in rats receiving total parenteral nutrition. | effects of different fatty acids on the development of hepatic steatosis were studied in rats receiving total parenteral nutrition (tpn). 65 rats, with internal jugular catheters, were divided into one control group (n = 8), and four experimental groups (n = 13-15 each). the control group was fed a chow diet and all experimental groups received tpn. tpn provided 300 kcal/kg/day with 40% of the non-protein energy provided as fat. all tpn solutions were isonitrogenous and identical in nutrient com ... | 1996 | 16843991 |
| effects of fish oil and safflower oil emulsions on diet-induced hepatic steatosis in rats receiving total parenteral nutrition. | this study was conducted to investigate the effects of fish oil and safflower oil emulsions in total parenteral nutrition (tpn) solutions on diet-induced hepatic steatosis. rats were divided into a control group (c, n = 6) and four experimental groups (a, b, s, f, n = 11 approximately 14). the control group was fed a chow diet whereas the experimental groups received a high fat (15%, w/w) diet containing 0.1% (w/w) cholesterol. group a received the high fat diet for 4 weeks, and was killed at th ... | 1996 | 16844003 |
| dietary fatty acids modulate host bacteriocidal response,microbial translocation and survival following blood transfusion and thermal injury. | the effect of dietary lipids on bacterial translocation, killing of translocated organisms and host survival was studied in a burned animal model. balb/c mice were fed with one of the three experimental ain-76a diets (containing 15% of energy from fish oil, safflower oil or a 50:50 mixture), ain-76a without added lipids or a nonpurified stock diet. all animals were transfused on day 10. on day 15, the animals were gavaged with 10(10) 14c radiolabelled escherichia coli and given a 20% burn injury ... | 1996 | 16844059 |
| [immunosuppression by parenteral lipid emulsions in a model of defined immunostimulation]. | the immunosuppressive effect of intravenous fat emulsions with different n-3/n-6 fatty acid ratio was studied in the heterotopic rat heart allotransplant model. twenty percent emulsions of safflower oil (n-3/n-6 = 1/370), fish oil (7.6/1), soybean oil (1/6.5) and a 1:1 mixture of safflower and fish oil (1/2, 1; oil control group) were continuously infused (9 g fat/kg b.w./day; n = 10 each group) after transplantation until rejection. graft survival time, subpopulations of infiltrating and circul ... | 1996 | 9429605 |
| [reduction of crude fiber content in safflower meal (carthamus tinctorius l) and its potential use in human food]. | the purpose of this work was to reduce the content of crude fibre (cf) and to determine the content of phenolics compounds (pc) and trypsin inhibitors (ti) in safflower meal (sm), in order to recommend the possibility of utilization it in human food. the sm (23.3% of cf, 22.4% of protein and 1.75% of pc was grinded in a blender and in a hammer mill respectively, after that, they were classified in particle size by sieving and compared with the sm and their fractions. grinding in hammer mill was ... | 1996 | 9429610 |
| effect of acute feeding of diets of varying fatty acid composition on intestinal apolipoprotein expression in the newborn swine. | the purpose of this study was to determine the effects of dietary fatty acids of varying chain lengths and degrees of saturation on intestinal apolipoprotein (apo) b and a-i expression in the newborn piglet. two-day-old female piglets received one of three isocaloric formulas containing 48% of total calories (120 kcal/kg/24 h) as medium-chain triglycerides (mct) from mct oil, intermediate-chain saturated triglycerides (icst) from coconut oil, or long-chain polyunsaturated triglycerides (lcput) f ... | 1996 | 8725273 |
| stimulation of the activities of hepatic fatty acid oxidation enzymes by dietary fat rich in alpha-linolenic acid in rats. | the activities of hepatic fatty acid oxidation enzymes in rats fed perilla oil rich in alpha-linolenic acid (alpha-18:3) were compared with those fed saturated fats or safflower oil (the mixture of safflower oil and olive oil, 94:8, w/w) containing the same amount of polyunsaturated fatty acids with perilla oil exclusively as linoleic acid (18:2). when the rats were fed the diets containing 15% coconut, safflower, and perilla oils for 1 week, the rate of mitochondrial and peroxisomal oxidation o ... | 1996 | 8728310 |
| comparative hypocholesterolemic effects of six vegetable oils in cholesterol-fed rat. | the hypocholesterolemic efficacies of various polyunsaturated fatty acids were compared in rats given cholesterol-enriched diets. oenothera biennis linn oil (oblo, linoleic + gamma-linolenic), sunflower oil (linoleic), palm oil (plo, oleic + linoleic), soybean oil (linoleic + alpha-linolenic), high-oleic safflower oil (oleic + linoleic), or mixed oil (linoleic + alpha-linolenic) was added to the diet at 200 g/kg (20% groups). oblo was also added at 100 g/kg diet (10% group). the serum total and ... | 1996 | 8743054 |
| effect of dietary fatty acids on jejunal and ileal oleic acid uptake by rat brush border membrane vesicles. | to test the effect of dietary fatty acids on fatty acid uptake, the influx kinetics of a representative long-chain fatty acid, 3h-oleic acid, in both the jejunum and ileum of rats has been studied using brush border membrane vesicles (bbmv). animals were fed with semipurified diets containing 5 g fat/100 g diet, as corn oil (control group), safflower oil (unsaturated group) and coconut oil hydrogenated (saturated group). with increasing unbound oleate concentration in the medium, the three dieta ... | 1996 | 9364039 |
| [physiological and biochemical study on the seed of carthamus tinctorius linn. at the primary stage of germination]. | 1996 | 9388920 | |
| beef tallow diet decreases uncoupling protein content in the brown adipose tissue of rats. | the effects of dietary fats consisting of different fatty acids on the content of mitochondrial uncoupling protein in the interscapular brown adipose tissue were studied in rats. sprague-dawley male rats were meal-fed an isoenergetic diet based on either beef tallow or safflower oil for nine weeks. the gain in body weight during the experimental period did not differ between the two dietary groups. the weight of the brown adipose tissue was similar in the two dietary groups, whereas the weight o ... | 1996 | 9089485 |
| effects of gamma-linolenic acid and its positional isomer pinolenic acid on immune parameters of brown-norway rats. | male brown-norway rats given purified diets containing safflower oil (sfo, linoleic acid, 18:2 n-6), evening primrose oil (epo, gamma-linolenic acid, 6,9,12- 18:3 n-6) or korean pine seed oil (pso, 5,9,12- 18:3) at the 10% level were immunized twice with intraperitoneal ovalbumin, on days 14 and 35 of the feeding diets, and killed one day after the second booster. the relative population of cd4+ t-lymphocytes in the spleen was significantly lower in rats fed sfo than in those fed epo or pso, whi ... | 1996 | 8951990 |
| activity of hepatic fatty acid oxidation enzymes in rats fed alpha-linolenic acid. | the activity of hepatic fatty acid oxidation enzymes in rats fed linseed and perilla oils rich in alpha-linolenic acid (alpha-18:3) was compared to that in rats fed safflower oil rich in linoleic acid (18:2) and a saturated fat (palm oil). palm and safflower oils were essentially devoid of alpha-18:3. the palmitoyl-coa oxidation rates both in mitochondrial and peroxisomal pathways in liver homogenates were significantly higher in rats fed linseed oil than in those fed palm and safflower oils. am ... | 1996 | 8954134 |
| efficient method for rapid induction of aberrant crypt foci in rats with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. | 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (phip) induces aberrant crypt foci (acfs) as well as colon cancer in f344 male rats. conditions allowing rapid development of acfs over a short period were investigated. f344 male rats were fed 400 ppm of phip x hcl in a low-fat diet (lf) for 2 weeks and then given a phip-free, high-fat diet containing primex (hf-pr) or safflower oil, or phip-free lf for 4 or 12 weeks. rats fed hf-pr for 4 weeks gave the highest number of acfs/rat (3.3) and their s ... | 1996 | 8957059 |
| abomasal infusion of cis or trans fatty acid isomers and energy metabolism of lactating dairy cows. | diets for dairy cows that provide or induce formation of trans isomers of polyunsaturated fatty acids result in reduced percentages of milk fat. the effect of abomasal infusion of trans-c18:1 fatty acid isomers on energy utilization by mature cows was determined. six multiparous holstein cows in midlactation had ad libitum access to a basal diet containing 50% forage and 50% concentrate. treatments were 1) no infusion, 2) infusion of 630 g/d of a fat mixture high in cis-c18:1 isomers (64% cis-c1 ... | 1996 | 8961107 |
| high-fat diet-induced hyperglycemia and obesity in mice: differential effects of dietary oils. | mice fed a high-fat diet develop hyperglycemia and obesity. using non-insulin-dependent diabetes mellitus (niddm) model mice, we investigated the effects of seven different dietary oils on glucose metabolism: palm oil, which contains mainly 45% palmitic acid (16:0) and 40% oleic acid (18:1); lard oil, 24% palmitic and 44% oleic acid; rapeseed oil, 59% oleic and 20% linoleic acid (18:2); soybean oil, 24% oleic and 54% linoleic acid; safflower oil, 76% linoleic acid; perilla oil, 58% alpha-linolen ... | 1996 | 8969289 |
| copper effect on photosynthesis and transpiration in safflower. | the young leaves of safflower plants subjected to deficient supply of copper (0.00063 mg cu l-1) developed visible symptoms of cu deficiency and showed a decrease in chlorophyll concentration, hill activity, net photosynthesis and transpiration. on giving normal supply of cu (0.063 mg cu l-1), these changes were partially reversed. | 1996 | 8979495 |
| effects of dietary fats and curcumin on ige-mediated degranulation of intestinal mast cells in brown norway rats. | brown norway rats were primed intraperitoneally with beta-lactoglobulin for 3 wk to induce reaginic antibody, during which time they were fed diets containing 10% each of coconut oil (co), high oleic safflower oil, safflower oil (so), or fish oil, then they were challenged for 3 h orally with the antigen. the dietary so, compared to other dietary fats, resulted in lower circulatory release of rat chymaseii (rchyii), an indicator of degranulation of mucosal mast cells in the intestine, in respons ... | 1996 | 8987863 |
| triterpene alcohols from the flowers of compositae and their anti-inflammatory effects. | eleven tabular and nine ligulate flowers from 15 species of compositae plants were investigated for their triterpene alcohol constituents. this led to the isolation and identification of 11 triterpene alcohols as follows: heliaol, taraxasterol, psi-taraxasterol, alpha-amyrin, beta-amyrin, lupeol, taraxerol, cycloartenol, 24-methyl-enecycloartanol, tirucalla-7,24-dienol and dammaradienol. the tabular flowers of calendula officinalis, carthamus tinctorius, cosmos bipinnatus, chrysanthemum morifoli ... | 1996 | 8987908 |
| effect of high fat diets with and without cholesterol on erythrocyte and tissue fatty acids in rats. | male weanling wistar rats were fed synthetic diets containing 20% safflower oil (sfo) or palm oil (po) with and without cholesterol for a period of six weeks. erythrocyte membranes were isolated and their fatty acid composition were determined at the end of the experiment. besides the fatty acid composition of the kidney and spleen lipids were also determined. erythrocyte membrane, kidney fatty acids of rats fed safflower oil (sfo) had in the majority of variants a higher level of n-6 fatty acid ... | 1996 | 9008832 |
| [comparison on the chemical constituents of chuanhonghua i with jianyang honghua]. | based on the qualitative reaction of chemical constituents and tlc, the chemical constituents of chuanhonghua-i were found similar to those jianyang honghua. the effective constituents, safflower haematochrome and safflower yellow contents of chuanhonghua-i, meet the standards of chinese pharmacopoeia (ed. 1990). | 1996 | 8758756 |
| the effects of olive oil upon rat serum lipid levels and lymphocyte functions appear to be due to oleic acid. | in order to investigate whether previously reported effects of feeding olive oil (oo) upon rat serum lipid concentrations and immune cell functions are due to oleic acid, weanling rats were fed for 6 weeks on diets containing 20% by weight of oo, safflower oil (so), or high oleic acid sunflower oil (hoso); a low-fat (lf) diet containing 2.5% by weight of lipid was used as a control. feeding the oo or hoso diets resulted in an elevated serum triacylglycerol concentration as compared with feeding ... | 1996 | 8773731 |
| effect of dietary n-3 deficiency on the electroretinogram in the guinea pig. | despite the abundance of n-3 polyunsaturated fatty acids, particularly docosahexaenoic acid (dha), in the retina of all mammals, their role in vision remains unclear. however, the widely accepted notion that dha is universally important in the retinal function was questioned in an earlier study (see text) involving guinea pigs, completely depleted of retinal dha. the purpose of this study was to replicate this mammalian model of such deficiency and to determine any abnormalities in the electrore ... | 1996 | 8773733 |
| erythrocyte morphology and filterability in rats fed on diets containing different fats and oils. | the present study aimed to determine if the type of dietary fat or oil affects erythrocyte morphology and/or filterability in normal healthy rats. a feeding trial was carried out, in which nine groups of nine rats were fed on diets containing one of the following treatments (test fats or oils): anhydrous milk fat, anhydrous milk fat after passage through a column of active carbon, palm oil, maxepa fish oil, hydrogenated coconut oil, anhydrous tallow shortening, margarine hardstock, olive oil and ... | 1996 | 8774223 |
| effect of beef tallow diet on alpha 2-adrenergic receptor binding in rat brain regions. | we examined the effects of dietary fats consisting of different fatty acids on alpha 2-adrenergic receptor binding in the hypothalamus and cerebral cortex. sprague-dawley male rats were meal-fed isoenergetic diets based on safflower oil or beef tallow for 8 weeks. alpha 2-adrenergic receptor bindings were determined with [3h]para-aminoclonidine. binding affinities of alpha 2-adrenergic receptor in the hypothalamus and cortex were significantly higher in the beef tallow diet group. the values of ... | 1996 | 8780971 |
| effect of dietary fat type on beta-oxidation of brown adipose tissue and na+ channel density of brain nerve membrane in rats. | effect of dietary fat type on beta-oxidation of brown adipose tissue and na+ channel density of brain nerve membrane was studied in rats. rats were fed an experimental diet containing lard, high oleic safflower oil, safflower oil or linseed oil for 12 weeks. the activities of carnitine palmitoyltransferase and cytochrome oxidase in brown adipose tissue were significantly lower in rats fed the lard diet than in those fed the high-oleic safflower oil diet, safflower oil diet or linseed oil diet. h ... | 1996 | 8780974 |
| gene expression of insulin signal-transduction pathway intermediates is lower in rats fed a beef tallow diet than in rats fed a safflower oil diet. | to elucidate the effects of dietary fatty acid composition on the insulin signaling pathway, we measured the gene expression of the earliest steps in the insulin action pathway in skeletal muscle of rats fed a safflower oil diet or a beef tallow diet. rats were meal-fed an isoenergetic diet based on either safflower oil or beef tallow for 8 weeks. both diets provided 45%, 35%, and 20% of energy as fat, carbohydrate, and protein, respectively. insulin resistance, assessed from the diurnal rhythm ... | 1996 | 8781294 |
| dietary fish oil and cytokine and eicosanoid production during human immunodeficiency virus infection. | dietary fish oil (fo) has been shown to modulate the immune system. the purpose of this study was to explore the effects of fo supplementation on the production of dienoic eicosanoids and cytokines in patients with human immunodeficiency virus (hiv) infection. | 1996 | 8788262 |
| interaction of 5,7-dihydroxy-4'-methoxyflavone with a multisubunit protein, carmin: thermodynamics and kinetics of interaction. | acacetin (5,7-dihydroxy-4'-methoxy flavone) is a flavone intrinsically present in the seeds of carthamus tinctorius. carmin is a multimeric, high molecular weight protein from the seeds of carthamus tinctorius. the association constant of interaction of acacetin and carmin is maximum at 37.2 degrees c with a value of (3.96 +/- 0.61) x 10(4) m-1 as measured by fluorescence quenching. acacetin has at least two binding sites on carmin. the interaction follows pseudo-first-order kinetics with a reac ... | 1996 | 8791154 |
| dietary fish oil prevents the development of renal damage in salt-loaded stroke-prone spontaneously hypertensive rats. | 1. stroke-prone spontaneously hypertensive rats (shrsp) fed a high salt diet rapidly develop proteinuria, a marker of renal damage. we have recently shown that supplementing the diet of these rats with pure omega-3 fatty acids can inhibit the development of proteinuria. the aim of the present study was to examine the underlying renal pathology and to see whether a similar benefit could be obtained with fish oil or canola oil. 2. diets containing sodium (2% by weight) and 5% fish oil, canola oil, ... | 1996 | 8800575 |
| posttranscriptional regulation of glucose-6-phosphate dehydrogenase by dietary polyunsaturated fat. | the activity of glucose-6-phosphate dehydrogenase (g6pd) is inhibited by the addition of polyunsaturated fat (pufa) to a high carbohydrate diet. to define the regulated step, we measured enzyme activity, accumulation of g6pd mrna, and transcriptional activity of the gene. at steady-state, g6pd activity and mrna abundance were inhibited by 80% in the livers of mice fed a high-fat diet (6% safflower oil) compared to mice fed a low-fat diet (1% safflower oil). inhibition of mrna accumulation was 20 ... | 1996 | 8806735 |
| vitamin c nutriture has little short-term effect on vitamin e concentrations in healthy women. | to determine whether the postulated sparing effect of vitamin e by ascorbic acid (aa) is important for human nutrition, we studied vitamin e status in 20 healthy pre-menopausal women (age 20-43 y) with high or low vitamin c intakes for 6 wk in a live-in metabolic unit. the experimental diet contained no fruits and vegetables and provided 5 mg/d of aa (recommended dietary allowance = 60 mg/d), 3 mg/d of alpha-tocopherol (rda = 10 mg/d) and 42 g/d of tocopherol-stripped safflower oil to increase t ... | 1996 | 8814216 |