Publications

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the antigens of vibrio cholerae involved in the vibriocidal action of antibody and complement. 19704986889
[sensitization by metabolic inhibitors of isolated intestine of rats to the effects of sympathomimetics. effects of fluoro-acetate and sodium mitride]. 19704987116
comparative morphological study of the major arterial supply to the pelvic limb of the domestic animals. 19704987407
effect of massive doses of bacteriophage on excretion of vibrios, duration of diarrhoea and output of stools in acute cases of cholera.each member of a group of 8 patients with acute cholera was treated with a mixture of four cholera bacteriophage preparations containing over 2 x 10(12) phage particles/ml. these massive doses were intended to kill immediately all vibrios in the intestine by "lysis from without". the numbers of vibrio cholerae were drastically reduced rapidly. in 4 patients, v. cholerae was completely eliminated from the stools early in the treatment; the total stool volume and after-treatment of diarrhoea were ...19704988693
some characteristics of the "lymphoid tumour" inducing agent of xenopus laevis. 19704989050
[pseudomonas aeruginosa sepsis treated with gentamycin]. 19704989827
comparative immunochemical studies of the toxic culture filtrates and endotoxin preparations from serologically identical strains of escherichia coli 2796-0129 and shigella flexneri 5. 19704990427
vibrio cholerae: production of toxin by a nonpathogenic strain. 19704992340
[organophosphate inhibitors as tools for the enzymologist]. 19704992978
[symposium. clinical and basic studies on viral exanthema]. 19704993207
production of biologically active substances by two strains of vibrio cholerae.strains inaba 569b and ogawa b1307 of vibrio cholerae were grown in shaken casamino acids-yeast extract-glucose medium at 30 and 37 c for 4 days. time courses of production of neuraminidase (nm), mucinase (mc), proteinase (pr), lytic factor (lf), and vascular permeability factor (pf) were compared by examining culture filtrates taken at various intervals. with both strains, turbidities were generally higher at 30 c than at 37 c. both strains showed marked cellular lysis after maximal growth was ...197016557700
bacteriocin typing of vibrio cholerae.bacteriocins of vibrio cholerae have been demonstrated against enterobacterial and vibrio indicator organisms by conventional techniques. abundant bacteriocin production took place on casein hydrolysate-yeast extract, tryptic soy, digest broth, proteose-peptone, and neopeptone agars. essential factors were a citrate-phosphate buffer concentration of 0.5 to 0.7%, at ph 7.5 to 7.6, and cold shock. thermal treatment of indicator organisms at 45 c for 12 min increased the percentage of typable strai ...197016557731
production of bacteriophage-associated materials by vibrio cholerae: possible correlation with pathogenicity.classical and el tor strains of vibrio cholerae were examined for production of bacteriophage or bacteriophage-related material by electron microscopy of mitomycin c-induced cultures. the strains were also tested for pathogenicity by using the ligated ileal loops of adult rabbits. of the 27 strains tested, 25 showed a correlation between the production of bacteriophage-related material and pathogenicity. both p(+) and p(-) strains produced bacteriophage tails. the bacteriophage tails of strains ...197016557750
biochemistry of vibrio cholerae virulence i. purification and biochemical properties of pf/cholera enterotoxin.a simple method for concentrating, isolating, and purifying pf/cholera enterotoxin from culture supernatant fluids is presented. precipitation with dextran sulfate and ammonium sulfate, followed by gel filtration and ion-exchange chromatography, yielded pf/enterotoxin of high biological potency. although not completely free from traces of vibriocidal antibody-stimulating activity, the resultant purified toxic immunogen appeared homogeneous as judged by immunoelectrophoresis, immunodiffusion, and ...197016557774
monospecific equine antiserum against cholera exo-enterotoxin.an antiserum specific for vibrio cholerae exo-enterotoxin was produced by immunization of a horse with purified choleragenoid, a natural cholera toxoid. the serum has a high titer against the toxin antigen in passive hemagglutination tests and a respectable antipermeability factor activity. it also passively protected against choleragen-induced mouse foot edema. the serum was found to be useful for assaying toxin antigen in crude and refined products by in vitro tests such as radial immunodiffus ...197016557901
mode of action of vibriocin: initial interaction with vibrio comma cells.certain metabolic requirements, upon initial interaction of sensitive cells with vibriocin, were a prerequisite for lethal activity. transient "immunity" of these cells, manifested under suboptimal growth conditions, differed from the immunity of vibriocinogenic cells.197116557939
immunochemical studies of two cholera toxin-containing standard culture filtrate preparations of vibrio cholerae.two crude toxin preparations of vibrio cholerae, labeled lot 4493 g (inaba) and lot 001 (ogawa), consisting of freeze-dried culture filtrate, were studied with regard to toxicity, precipitinogenicity, and chemical composition. lot 4493 g contained much more carbohydrate and less protein than lot 001, but both of the preparations contained three precipitinogens which were identical. one of these factors was identified as cholera exotoxin. in addition, both contained a fourth cross-reacting precip ...197116558049
serological properties of gammag and gammam antibodies to the somatic antigen of vibrio cholerae during the course of immunization of rabbits.direct- and passive-agglutinating, complement-fixing, and bactericidal properties of gammag and gammam antibodies produced in rabbits inoculated with live vibrio cholerae were determined at intervals over a period of 345 days. although gammam antibody titers increased more rapidly than gammag during the initial stages of antibody production, the titers of gammag and gammam declined proportionally during a 3-month rest period and increased proportionally after a booster injection. the relative ti ...197116558058
bronchial eosinophilia in rhesus monkeys with ige mediated respiratory responses. 19714993765
isolation of purified allergens (cod) by isoelectric focusing. 19714993766
isolation of a basic protein antigen of low ragweed pollen. 19714994362
[differentiation of the trophoblast during in vitro development of the mouse embryo]. 19715088018
filamentation of vibrio cholerae cells by furazolidone. 19715092750
holding media for the transport of vibrio cholerae from field to laboratory. 19715093666
the development of the muscles of mastication in the rat. 19715093712
cells persistently infected with newcastle disease virus. 3. thermal stability of hemagglutinin and neuraminidase of a mutant isolated from persistently infected l cells.data were obtained which indicated the possible cause of the defective elution from erythrocytes of the mutant virus (ndv(pi)) isolated from l cells persistently infected with the herts strain of newcastle disease virus (ndv(o)). the chicken erythrocyte receptors for the mutant and wild-type viruses were equally sensitive to the action of vibrio cholera filtrate neuraminidase; this suggests that the failure of ndv(pi) to elute from chicken erythrocytes is not due to a specific neuraminidase-resi ...19715101091
[acute kidney failure due to immunohemolytic anemia following consumption of the mushroom paxillus involutus]. 19715105189
[handy tube constructor]. 19715106401
human vibrio cholerae: a histologic review of 117 cases in the philippines. 19715112342
increase of leukemia l1210 immunogenicity by vibrio cholerae neuraminidase treatment. 19715120303
agglutinin and vibriocidal responses of l forms of vibrio cholerae and el tor. 19715121765
enzymatic action of sialidase of vibrio cholerae on brain gangliosides above and below the critical micelle concentration. 19715135317
enzymatic and biological studies of cholera (vibrio cholerae) toxin. 19715139517
vasoactive drugs on intestinal fluid secretion induced by vibrio cholera toxin. 19715146323
transmissible plasmid factors and fertility inhibition in vibrio cholerae. 19715148720
[recent acquisitions regarding carriers of vibrio cholerae]. 19715153353
passive protection of mice against intraperitoneally injected vibrio cholerae by g and m antibody.fractions of rabbit anti-vibrio cholerae serum containing gammag antibodies were compared with fractions containing gammam antibodies for their ability to protect mice against lethal infection resulting from the intraperitoneal injection of organisms suspended in mucin. about twice as much gammag as gammam (estimated by quantitative precipitation) was required to protect against approximately 1,000 50% lethal doses when the antibody was given intraperitoneally 4 hr before challenge. when protect ...19715154896
experimental cholera produced by vibrio cholerae and choleragenic filtrates: light and electron microscopic findings in the small intestine. 19715157926
kinetics of adsorption of a group iv cholera phage. 19715161466
the vibrio cholerae isolated during cholera epidemics in korea in 1969 and 1970. 19715161480
[current pathogenetic, clinical and therapeutic aspects of cholera]. 19715162745
effect of anaerobiosis on vibriocin activity. 19715163070
quantitative assay of a protein antigen of vibrio cholerae involved in the vibriocidal action of antibody and complement. 19715170447
biochemistry of vibrio cholerae virulence. ii. skin permeability factor-cholera enterotoxin production in a chemically defined medium.a chemically defined medium capable of eliciting high titers of skin permeability factor (pf)/enterotoxin from three different strains of vibrio cholerae has been developed. toxin/antigen elaboration in synthetic and in complex media was monitored by a specific passive hemagglutination-inhibition test. a distinct temporal difference in the pattern of toxin/antigen elaboration was noted when the two types of media were compared. in complex media, pf activity and corresponding antigen release were ...19715170548
observations on the haemolytic character of vibrio cholerae in a medium containing glycerol. 19715170657
the unmasking of receptors for rubella virus by trypsinization of red cells. 19715170743
a quantitative approach to epidemiology and control of cholera. 19715172696
[diversity of lysogenic states among el tor vibrios of various origins]. 19715172697
[episomal resistance of the cholera vibrio to penicillin]. 19715211302
human lymphocyte antigen reactivity modified by neuraminidase.human lymphocytes treated with neuraminidase (from vibrio cholera) are more susceptible to lysis with antiserums directed against hl-a antigens in the cytotoxicity test than are the corresponding cells incubated in buffer. enzymetreated cells are also lysed by antibodies other than those directed against hl-a, but control cells are not. the extra sensitivity to antibody disappears after 2 to 6 days in tissue culture.19715564043
amino acid and nitrogen metabolism in chick embryos infected with staphylococcus aureus or vibrio cholerae. 19715570558
comparative electrophoretic and serological analyses of vibrio comma and aeromonas liquefaciens proteinases. 19714999791
paradoxical synergism and antagonism between serum and the antibacterial activity of colistin. 19714999904
simultaneous use of contrasting fluorochromes to separate measles and canine distemper viruses in a common system.measles and canine distemper viruses were grown together in a vero monkey kidney cell line. each virus could be identified and individually titrated by using the color contrast produced by the reddish tetra-methyl rhodamine isothiocyanate-tagged antimeasles conjugate and the green fluorescein isothiocyanate-tagged antidistemper conjugate. both blue light and green light were used for the excitation of the fluorochromes. incident light was transmitted to the specimen by a vertical illuminator of ...19715000868
relationship between phosphates and alkaline phosphatase of anabaena flos-aquae in continuous culture. 19715001948
[studies on the storage and metabolism of 3,4-benzpyrene (benzo-(a)-pyrene) in microorganisms]. 19715002946
[studies of cholera cerisis inhibiting factor. 1. isolation and specificity of the active substances from the small intestine of rabbits immunized with inactivated vibrio cholerae]. 19715004220
characterization of two sucrase activities in bacillus subtilis marburg. 19715004826
[vibrio cholera precipitating antigens. their relation to agglutinant and immunofluorescent antigens]. 19715005225
blocking of 5-methoxy-n-dimethyltryptamine-induced eeg alerting in the rabbit by previous administration of antiserum to this compound. 19715005932
mechanism of mercuric chloride resistance in microorganisms. i. vaporization of a mercury compound from mercuric chloride by multiple drug resistant strains of escherichia coli. 19714947308
[quantitative assay of colicin inactivation by the culture filtrate of vibrio cholerae]. 19714947606
on the stereochemical basis of enzyme action: lessons from lysozyme. 19714949243
interaction between phage t4b dna and membrane structures of the cell. 19714949476
[characteristics and localization of lipids in the abomasum wall of the suckling calf]. 19714949924
[ulcerative endocarditis caused by salmonella-suis var. kunzendorf]. 19714944907
[isolation and identification of vibrio cholerae]. 19714930662
vibrio agar: a new plating medium for isolation of vibrio cholerae. 19715314746
somatic antigen variation in vibrio cholerae. 19715314749
a comparison of jejunal response to cholera exotoxin and to hypertonic mannitol. 19715317651
distribution and disappearance rate of renin in man and dog. 19714997580
morphological studies on herpesvirus saimiri in subhuman and human cell cultures. 19714997845
isolation and purification of a peptido-rhamnomannan from the yeast form of sporothrix schenckii. structural and immunochemical studies. 19714999090
collie eye anomaly. 19714994718
tissue dissociation with proteolytic enzymes. adsorption and activity of enzymes at the cell surface. 19714995054
[the precipitating antigens of vibrio cholerae]. 19714995964
enzymoserological relationships between vibrio comma and other gram-negative organisms. 19714996635
the oxygen effect and radiotherapy with fast neutrons. 19714996862
[total autologous transplantation of the uterus in the female dog. technical, clinical and anatomical study of 15 cases]. 19714933901
aspects of chromosomal structure. i. circular dichroism studies. 19714934117
the pathophysiology of ovine ostertagiasis: water balance and turnover studies. 19714934254
comparative effects of enterotoxins from escherichia coli and vibrio cholerae on rabbit and swine small intestine. 19714934433
the isolation and identification of vibrio cholera--a review. 19714934937
the reaction of the intrarenal sympathetic nervous system to renal transplantation. 19714937332
immunotherapy of cancer: immunospecific rejection of tumors in recipients of neuraminidase-treated tumor cells plus bcg.firmly established methylcholanthrene fibrosarcomas in syngeneic mice will totally disappear if the hosts are treated with living tumor cells that have been exposed to vibrio cholerae neuraminidase in vitro. the effect is magnified by the simultanieous injection of a nonspecific immunostimulant, bcg. the rejection of the methylcholanthrene tumor is immunospecific and can be induced only with tumor cells, treated with vibrio cholerae neuraminidase, identical in type with the growing tumor.19714940021
monitoring of low-level virus in natural waters.the insoluble polyelectrolyte technique for concentrating virus is extended to extremely low virus levels. the effectiveness of this method employing a coliphage t2 model is a constant 20% over a range of virus levels from 10(3) to 10(-4) plaque-forming units/ml. the efficiency of the method is dependent upon ph control during the concentration phase. although the study was initiated to develop a method for quantitating the effectiveness of water and wastewater treatment methods for the removal ...19714940873
short-term cultures of mouse marrow cells separated by velocity sedimentation. 19714942466
immunological unresponsiveness against the 4-hydroxy-3,5-dinitro-phenacetyl (nnp) hapten in different lymphoid cell populations. 19714942472
divergence between immunosuppression and immunocompetence during virus-induced leukemogenesis.mice were infected with friend leukemia virus and later immunized with either vibrio cholerae vaccine or sheep erythrocytes. the primary antibody response to the bacteria (as judged by the number of plaque-forming cells) was slightly enhanced by the viral infection, whereas the response to sheep erythrocytes was inhibited. the difference appeared due to sensitization of mice to antigens crossreacting with those of sheep erythrocytes; no natural immunity to v. cholerae is detectable. however, the ...19714942915
regulation of the pulmonary circulation.factors regulating pressure and flow in the lungs are reviewed with particular emphasis on their role in regulating blood flow velocity and distribution within the lung capillaries. the behaviour of the pulmonary arterial, system, alveolar capillaries, and pulmonary venous system are considered individually. the effect of heart disease on lung capillary blood flow is examined.19714929437
antibody plaque responses of mice given vibrio cholerae antigen as neonates. 19714930067
[bacteriology of the tracheobronchial system]. 19714399107
antibody response of normal and germ free rats to injected sheep erythrocytes when held in a helium--oxygen atmosphere. 19714399742
[kinetic and chemical experiments on the decay of di-n-acetylneuraminosyl-lacto-n-tetraose by neuraminidases of myxoviruses and vibrio cholerae]. 19714401630
interactions of avian sarcoma virus with rat embryo cells in cell culture. 19714330345
the group-specific antigen and other structural proteins of hamster and mouse c-type viruses. 19714330369
[new biologically active copolymers of n-vinylpyrrolidone]. 19714330729
ultrastructural and biochemical studies on ribonucleoprotein particles from isolated nucleoli of thioacetamide-treated rat liver. 19714330914
enhanced mitochondrial functions during heptatocarcinogenesis. 19714331095
[presence of nuclear inclusions in the cells of the human placenta]. 19714338058
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