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[analysis of content uniformity of dosage units of chinese patent medicines]. 20123416384
[chemical sympatholysis guided by computerized scanning]. 20123346620
arteriolar oxygen reactivity: where is the sensor?the hypothesis that arterioles are intrinsically sensitive to oxygen was tested by comparing arteriolar diameter responses with local and global po2 changes in superfused hamster cheek pouch preparations. local po2 changes were produced by microapplication of fluid onto the surface of occluded or unoccluded aparenchymal arterioles or by cannulation and perfusion of arterioles in situ. global changes refer to po2 changes in the superfusate flowing over the entire preparation. local, effective po2 ...20123318502
molecular characterizations of cytolethal distending toxin produced by providencia alcalifaciens strains isolated from patients with diarrhea.cytolethal distending toxins (cdts), which block eukaryotic cell proliferation by acting as inhibitory cyclomodulins, are produced by diverse groups of gram-negative bacteria. active cdt is composed of three polypeptides--cdta, cdtb, and cdtc--encoded by the genes cdta, cdtb, and cdtc, respectively. we developed a pcr-restriction fragment length polymorphism assay for the detection and differentiation of five alleles of cdtb (cdt-i through cdt-v) in escherichia coli and used the assay to investi ...201222252871
[rapid decisions in the situation of dichotic choice: an integrated approach which takes into account onset snd execution of the response]. 20123502909
measurement of monoclonal immunoglobulin concentrations in hybridoma cultures by competitive inhibition enzyme immunoassay. 20123523131
evaluation of food protective property of five natural products using fresh-cut apple slice model.the present study evaluated the antioxidant (aa), antimicrobial and preservation effects of five plant derived natural products viz., rosmarinic acid (ra), p-coumaric acid (pca), trans-cinnamic acid (tca), hydroxyphenyllactic acid (hpa) and caffeic acid (ca) along with synthetic compounds (ascorbic acid, gallic acid, citric acid and bha) on fresh cut apple slices. antimicrobial efficacy of these compounds against bacillus licheniformis, pseudomonas vulgaris, shigella boydii, salmonella typhi, st ...201222530437
a genomic island in salmonella enterica ssp. salamae provides new insights on the genealogy of the locus of enterocyte effacement.the genomic island encoding the locus of enterocyte effacement (lee) is an important virulence factor of the human pathogenic escherichia coli. lee typically encodes a type iii secretion system (t3ss) and secreted effectors capable of forming attaching and effacing lesions. although prominent in the pathogenic e. coli such as serotype o157:h7, lee has also been detected in citrobacter rodentium, e. albertii, and although not confirmed, it is likely to also be in shigella boydii. previous phyloge ...201222860002
evidence of interspecies o antigen gene cluster transfer between shigella boydii 15 and escherichia fergusonii.an environmental bacterial isolate, iso10, previously found to show serological cross-reactivity with type-specific shigella boydii 15 antisera was subjected to further molecular and serological analyses that revealed interspecies transfer of the o antigen gene cluster. western blot analysis of iso10 cell surface extracts and purified lipopolysaccharides demonstrated strong cross-reactivity with s. boydii 15-specific monovalent antisera and a lipopolysaccharide gel banding profile similar to tha ...201223030400
studies on shigella boydii infection in caenorhabditis elegans and bioinformatics analysis of immune regulatory protein interactions.shigella boydii causes bacillary dysentery or shigellosis and generates a significant burden in the developing nations. s. boydii-mediated infection assays were performed at both physiological and molecular levels using caenorhabditis elegans as a host. continuous exposure of worms to s. boydii showed a reduced life span indicating the pathogenicity of shigella. quantitative real-time pcr analysis was performed to analyze the expression and regulation of host specific candidate-antimicrobial gen ...201222841995
outer membrane vesicles of shigella boydii type 4 induce passive immunity in neonatal mice.like most other gram-negative bacteria, shigella releases outer membrane vesicles (omvs) into the surrounding environment during growth. in this study, we have exploited omvs of shigella as a protective immunogen in a mice model against shigellosis. distinctive vesicle secretion was noticed from different shigella strains. among them, shigella boydii type 4 (bch612) was secreting relatively higher amounts. we immunized female adult mice orally with 32 μg of purified shigella boydii type 4 (bch61 ...201222762732
effect of bovine lactoferrin on the minimum inhibitory concentrations of ampicillin and trimethoprim-sulfamethoxazole for clinical shigella spp. strains.here, we determined the effect of bovine lactoferrin (blf) on the minimum inhibitory concentration (mic) of ampicillin and trimethoprim-sulfamethoxazole in shigella . using a microdilution method, the mic was determined in the presence or absence of bovine lactoferrin (10 mg/ml) on 88 shigella strains (56 shigella flexneri , 15 shigella boydii , 13 shigella sonnei , and 4 shigella dysenteriae ) previously isolated from peruvian children <2 years old. a fold change of 2 or more in mic values was ...201222397495
antimicrobial-resistant shigella infections from iran: an overlooked problem?in this study, we wanted to assess the level of antimicrobial resistance, the presence of genes encoding resistance to cephalosporins and plasmid-mediated quinolone resistance (pmqr), and genetic relatedness among shigella isolates obtained from iranian patients.201222345385
[characteristics of nasal breathing and of the surgical procedure in nose deformities following the primary operation for unilateral cleft upper lip]. 20123472396
[mandibular prognathic syndrome and its surgical correction by simultaneous total maxillary and mandibular osteotomies]. 20123472839
patterns of lactate dehydrogenase isoenzymes in serum of patients with acute pulmonary edema.total lactate dehydrogenase (ld; ec 1.1.1.27) activity in serum and proportions of ld isoenzymes were quantified on admission and discharge in 170 selected (from 240) patients with acute pulmonary edema (ape). the patients were divided into group a, 75 patients with normal ld values (less than 225 u/l); and groups b-e, with increased ld activity in serum: group b, 40 patients with increase in the proportion of ld-3 (greater than 38%); group c, 12 patients with increased ld-5; group d, 36 patient ...20123416439
clonal diversity of the kirsten-ras oncogene during tumor progression in athymic nude mice: mechanisms of amplification and rearrangement.single-cell clones from primary and lung metastatic tumors have been evaluated for the state of the viral-kirsten-ras oncogene (v-ki-ras) by southern blot analysis after injection of kirsten sarcoma virus-transformed balb/c 3t3 cells (kimsv, with a replication-defective provirus) into athymic nude mice by four different injection routes. while all clones of early-passage kimsv cells contained an ecori-generated 5.3-kilobase dna fragment at high dosage level, most clones of late-passage cells had ...20123409227
ball thrombi in carotid artery plaque. 20123629659
analysis of host-parasite coevolution. 20123294641
natural selection and the heritability of fitness components.the hypothesis that traits closely associated with fitness will generally possess lower heritabilities than traits more loosely connected with fitness is tested using 1120 narrow sense heritability estimates for wild, outbred animal populations, collected from the published record. our results indicate that life history traits generally possess lower heritabilities than morphological traits, and that the means, medians, and cumulative frequency distributions of behavioural and physiological trai ...20123316130
double-blind clinical trial of s-adenosylmethionine versus ibuprofen in the treatment of osteoarthritis.thirty-six subjects with osteoarthritis of the knee, the hip, and/or the spine were enrolled in a randomized double-blind study. patients received a daily oral dose of 1,200 mg of s-adenosylmethionine (same) or 1,200 mg of ibuprofen for four weeks. morning stiffness, pain at rest, pain on motion, crepitus, swelling, and limitation of motion of the affected joints were assessed before and after treatment. the total score obtained by the evaluation of all the individual clinical parameters improve ...20123318445
treatment of external resorption by a combined endodontic-periodontic procedure. 20123465861
[tuberculosis in necropsies]. 20123347110
redressing the balance. 20123292931
[use of auxiliary measures within the scope of extracorporeal shockwave lithotripsy]. 20123368891
the measurement of socioeconomic inequality and social class in australia: a review of past practices and recent developments. 20123370944
the incidence of symptomatic urolithiasis in royal naval submariners comparison with personnel of the surface fleet. 20123256633
chromogenic reactions of tertiary amines with polycarboxylic acids and acetic anhydride: carbon suboxide as the reactive species in the malonic acid reagent.analytical methods based on the title reactions are reviewed, and the malonic acid-acetic anhydride system was selected for detailed study. it is postulated that carbon suboxide, o = c = c = c = o, formed by the action of acetic anhydride on malonic acid, is the effective reactive species in this system. carbon suboxide was prepared and identified, and spectrophotometric observations of its reactions with tertiary amines are described. aliphatic and aromatic tertiary amines generate colored prod ...20123430350
endoscopy-controlled study of the safety of nabumetone compared with naproxen in arthritis therapy.nonsteroidal anti-inflammatory drug (nsaid) gastropathy is now a commonly recognized and reported complication of such arthritis therapy. significant gastric lesions develop in up to 40 percent of arthritic patients treated with long-term anti-inflammatory doses of nsaids, 20 percent of which represents actual ulcer crater disease. this 12-week endoscopy-controlled, double-blind study was constructed to evaluate the safety and efficacy of nabumetone 1,000 mg at bedtime compared with naproxen 250 ...20123318424
conservative treatment of fingertip injuries.in a prospective investigation of 81 consecutive patients with fingertip injuries conservative treatment was evaluated. fingertip injuries were defined as lesions greater than or equal to 1 cm2 in the terminal phalanx without injury to the tendons or joints. all fingertip injuries were cleaned and covered by vaseline gauze and left to heal. if less than 2 mm of soft tissue covered the bone a few millimetres of bone were nibbled away to allow good cover with soft tissue. the majority of injuries ...20123508851
[ferric sulfate in minor oral surgery]. 20123488235
[the effect of radio- and chemotherapy on survival in advanced head and neck tumors].inoperable cases of advanced squamous cell carcinomas in the head and neck area which have a very poor prognosis are often treated by a combined radio- and chemotherapy. tumor remissions up to 70% are induced by both radiotherapy and chemotherapy alone; an increase of the survival time is not reported. the present randomized study investigates the efficacy of two therapy schemes, i.e. chemotherapy alone and chemotherapy combined with irradiation. tumor remissions of 75% were achieved in 80 evalu ...20123296260
artificial insemination with cryopreserved donor semen: a decade of experience.ten years' experience of artificial insemination with cryopreserved donor semen for 1023 courses in 783 women resulting in 572 pregnancies is reported. a simple approach with multiple inseminations timed on the basis of cycle length, temperature charts, mucus symptoms and signs was used. the life table pregnancy rate was 61% after 12 cycles of treatment and 75% after 24 cycles. women had a significantly higher rate of pregnancy in second and subsequent courses of treatment, and the pregnancy rat ...20123382608
polypoid neurilemmoma of the trachea: an unusual cause of major airway obstruction.neurilemmomas (schwannomas) of the trachea are extremely rare. a case of near-total obstruction of the trachea by an intraluminal polypoid neurilemmomas is reported. computerized tomographic imaging gave the exact localization of the polyp and the attachment of its stalk. endoscopic excision has left the patient with an excellent prognosis and little chance of recurrence.20123250429
[use of dna-dna hybridization methods for studying the epidemiology and evolutionary similarity of drug resistance determinants].a procedure for rapid mass assay of clinical strains of microorganisms based on dna-dna hybridization was developed. epidemiology of the gentamicin resistance determinant cloned earlier from clinical strains of the same hospital was studied and its plasmid localization in representatives of various genera of enterobacteriaceae was confirmed. the studies on dot-hybridization showed that in three antibiotic-producing organisms, i.e. s. fradiae 918 producing neomycin, m. purpurea 1535 producing gen ...20123521468
infectious interstitial emphysema in aids. 20123497367
[erythrocyte longevity in hypoplastic anemia patients undergoing splenectomy as part of combined treatment].a study was made of the survival time of erythrocytes labeled with 51cr in 30 patients with hypoplastic anemia. in 96.7% of the patients erythrocyte survival time was reduced (from 18 to 3.6 days; an average of 11.8 days), an increase in the number of macrocytes was noted (in 83.3%). the mean volume and thickness of erythrocytes were also on an increase (in 95.8%); a decrease in the spherical index of erythrocytes was noted (in 91.6%). in this connection erythrokaryocyte proliferation enhancemen ...20123424200
glucoregulatory effects of bombesin in lean and genetically obese hyperglycaemic (ob/ob) mice.1. plasma glucose and insulin responses to bombesin were examined in 12-15-week-old 12 hr fasted lean and genetically obese hyperglycaemic (ob/ob) mice. 2. bombesin (1 mg/kg ip) produced a prompt but transient increase of plasma insulin in lean mice (maximum increase of 50% at 5 min), and a more slowly generated but protracted insulin response in ob/ob mice (maximum increase of 80% at 30 min). plasma glucose concentrations of both groups of mice were increased by bombesin (maximum increases of 4 ...20123315420
[effect of anaprilin on the humoral and cellular immune response].the immunosuppressive effect of anaprilin on humoral and cellular responses was established during experiments on mice. the influence of the drug on the phenomenon of hypersensitivity of delayed type begins to be revealed at the lower dose of the drug (0.5 mg/kg) as compared with the inhibitory action of the beta-adrenoblocker on antibody formation (1 mg/kg).20123609279
[principles of geriatric pharmacology. 1. pharmacokinetics and pharmacodynamics]. 20123255626
shigella strains are not clones of escherichia coli but sister species in the genus escherichia.shigella species and escherichia coli are closely related organisms. early phenotyping experiments and several recent molecular studies put shigella within the species e. coli. however, the whole-genome-based, alignment-free and parameter-free cvtree approach shows convincingly that four established shigella species, shigella boydii, shigella sonnei, shigella felxneri and shigella dysenteriae, are distinct from e. coli strains, and form sister species to e. coli within the genus escherichia. in ...201223395177
[nonocclusive ischemic enteropathy--a rare cause of ileus].the cause for a nonocclusive ischemic enteropathy seems to be a low cardiac output syndrome. there are often signs of a paralytic intestinal obstruction. parameters of the blood chemistry offer no conclusive data. the angiogram of the mesenteric vessels demonstrates extensive arterial vasoconstriction as well as an obstructed venous outflow. experimental findings disclose that this venous obstruction may be a result of an ischemic contracture in the course of a low flow state. this rigor initiat ...20133840557
[glomerulonephritis following infections]. 20133795528
change of blood pressure over five years in childhood and adolescence.we compared blood pressure (bp) values, measured at a five year interval, in 2,777 boys and girls aged 4-18 years. bp values were converted into height and sex adjusted standard deviation unit scores. correlation coefficients were significant but low for systolic bp score: 0.19 in boys and 0.15 in girls, and were even lower for diastolic bp score. these correlations are weaker than those observed for overall bp values (boys: 0.33, girls: 0.23), weight (0.82, 0.75) and height (0.87, 0.80). the pr ...20133757275
ovarian heterologous sertoli-leydig cell tumors with gastrointestinal-type epithelium. an immunohistochemical analysis.eight ovarian heterologous sertoli-leydig cell tumors containing gastrointestinal-type cells, including two tumors that contained carcinoids, were stained for argyrophilia and argentaffinity; in addition, these specimens were stained by immunohistocytochemical techniques for the demonstration of chromogranin, serotonin, and a variety of peptide hormones. intestinal- and gastric-type epithelial and carcinoid cells within the tumors were focally argyrophilic and chromogranin-positive, but only int ...20133754727
[the empty delta sign. a useful or misleading sign in cerebral x-ray computed tomography?].one case of bifidity of the superior sagittal sinus, resulting in a false "empty delta sign", is presented. the authors emphasize the importance of the indirect signs of sinovenous thrombosis, i.e. cerebral edema and multiple or bilateral hemorrhagic infarcts, in the diagnosis of true empty delta sign.20133701671
depression and urinary free cortisol. 20133697593
clinical overview of alpha interferon. studies and future directions.the clinical development of the alpha interferons has now progressed through initial phase i and ii trials into extensive controlled clinical trial designs. alpha interferon has been a prototype of other biological agents that are now in clinical development. these agents operate through fundamentally different mechanisms of action than conventional chemotherapy and have produced a unique profile of side effects as well as response patterns. time to response is generally longer than with chemoth ...20133542185
[acoustic indicator of membrane potential levels]. 20133609385
initiation of aerobic oxidation of sulfite by illuminated spinach chloroplasts. 20134144355
phase manipulation, shift work, and jet lag: an overview.this overview stresses why it is important to avoid the effect of masking and presents a model of the mechanism of circadian synchronization based on circadian changes of nonspecific responsiveness to various zeitgeber qualities. the significance of phase responses, transitory uncoupling, frequency multiplication, and flattening of circadian functions is considered. even circadian adaptation undergoes a circaseptan reactive periodicity.20133628348
[multiple breast metastasis of cutaneous malignant melanoma]. 20133838028
efficacy of alcohol-based hand rinses under frequent-use conditions.fifty volunteers randomly assigned to one of five hand washing agents (10 subjects per agent)--a nonantiseptic liquid soap (control), an antiseptic hand rinse containing 60% isopropyl alcohol (ipa) with emollients (alc a), an antiseptic hand rinse containing 70% ipa and 0.5% chlorhexidine gluconate with emollients (alc b), an antiseptic containing 4% chlorhexidine gluconate and 4% ipa (chg), and 70% ipa--washed their hands 15 times per day for 5 days under supervision by using a standardized tec ...20133789690
[practice of oriental medicine. 8. etiology and internal and external symptoms]. 20133639179
antimicrobial activities of some flavonoid compounds.6 flavonoid compounds, namely kaempferol, quercetin, myricetin, rutin, naringin, and formononetin were separated from different plant materials. they were identified using column and paper chromatography techniques, and physicochemical methods were applied to determine their structure. isolated flavonoids were tested for their antimicrobial property against different bacterial and fungal strains as test organisms.20133811648
[the royal morocco academy]. 20133910181
[health behavior and self care: postulations and theories in health sociology]. 20133864276
comparison of beta enolase and myoglobin as histological markers of rhabdomyosarcoma.a comparative study of beta enolase and myoglobin as markers of muscle differentiation in rhabdomyosarcoma was carried out, using an immunoperoxidase peroxidase antiperoxidase technique. material from 26 cases of childhood rhabdomyosarcoma was studied and subdivided into embryonal and alveolar types. positive cytoplasmic staining for beta enolase was seen in 85% of tumours studied (91% alveolar, 79% embryonal), whereas positive staining for myoglobin was detected in only 69% of tumours (82% alve ...20133905869
lithium: long-term effects on the kidney--ii. structural changes.forty-six patients treated with lithium for an average of 8 yr participated in a follow-up study involving a kidney biopsy. the results were compared with renal biopsy specimens from an age-matched group of controls never treated with lithium. the average number of totally scelerotic glomeruli and atrophic tubuli was higher in lithium-treated patients. the histopathological changes showed significant correlations with lithium dosage schedule. both the proportions of sclerotic glomeruli, atrophic ...20133681762
protective immunity by oral immunization with heat-killed shigella strains in a guinea pig colitis model.the protective efficacy of and immune response to heat-killed cells of monovalent and hexavalent mixtures of six serogroups/serotypes of shigella strains (shigella dysenteriae 1, shigella flexneri 2a, s. flexneri 3a, s. flexneri 6, shigella boydii 4, and shigella sonnei) were examined in a guinea pig colitis model. a monovalent or hexavalent mixture containing 1 × 10(7) of each serogroup/serotype of heat-killed shigella cells was administered orally on days 0, 7, 14 and 21. on day 28, the immuni ...201324033533
characterization and complete genome sequence of the shigella bacteriophage psf-1.shigellosis is a global health problem, and shigella flexneri is the major cause of this disease. in this study, we isolated a virulent siphoviridae bacteriophage (phage), psf-1, that infects s. flexneri. this phage was isolated from the han river in korea and was found to infect s. flexneri, shigella boydii, and shigella sonnei. one-step growth analysis revealed that this phage has a short latent period (10 min) and a large burst size (86.86 pfu/cell), indicating that psf-1 has good host infect ...201324012542
multi-serotype outer membrane vesicles of shigellae confer passive protection to the neonatal mice against shigellosis.recently, we have demonstrated, immunization of adult female mice with outer membrane vesicles (omvs) of shigella boydii type 4 protected their offspring passively from shigellosis. in our present study, we have advanced our research by formulating multi-serotype outer membrane vesicles (momvs), mixing the omvs of shigella dysenteriae 1 δstx, shigella flexneri 2a, 3a and 6, s. boydii type 4 and shigella sonnei to achieve a broad spectrum protection against shigellosis. adult mice were immunized ...201323684822
phage inactivation of foodborne shigella on ready-to-eat spiced chicken.shigellosis, also called bacillary dysentery, is an infectious disease caused by shigella species, including shigella flexneri, shigella dysenteriae, shigella sonnei, and shigella boydii. infection with s. flexneri can result in epidemics, and shigella-contaminated food is often the source of infection, such as ready-to-eat spiced chicken and duck. therefore, we investigated the ability of shigella phages to inhibit pathogenic shigella spp. in ready-to-eat spiced chicken. food samples were inocu ...201323243250
chemical and antimicrobial studies on the essential oil from salvia santolinifolia boiss.in view of the reputation of genus salvia in folklore medicine and its abundance in our region, the chemical composition and antimicrobial activity of essential oil from s. santolinifolia boiss. was analyzed. chemical analysis, using gas chromatography and gas chromatography mass spectrometry, retention indices and c-13 nuclear magnetic resonance spectroscopy has resulted in identification of 116 constituents, comprising about 97% of the total constituents. out of these 116, 78 constituents are ...201323261726
role of porin proteins in acquisition of transferrin iron by enteropathogens.acquisition of iron from key innate immune defence proteins such as transferrin (tf) and lactoferrin is an important mechanism by which pathogenic bacteria obtain essential iron for growth within their host. bacterial species that do not produce siderophores often use specific tf-binding proteins, the best characterized being the neisseriaceae-type tf-binding proteins tbpa and tbpb. previous work from our laboratory has shown that siderophore-producing enteric species such as escherichia coli al ...201324089578
oxalis corniculata (oxalidaceae) leaf extract exerts in vitro antimicrobial and in vivo anticolonizing activities against shigella dysenteriae 1 (nt4907) and shigella flexneri 2a (2457t) in induced diarrhea in suckling mice.in this study, the extract of a green leafy vegetable oxalis corniculata (oxalidaceae) was evaluated for its in vitro antibacterial and in vivo anti colonizing effect against common intestinal pathogenic bacteria. methanolic extract (80%) of oxalis corniculata (oxalidaceae) leaf contained a polyphenol content of 910 mg gallic acid equivalent per gram of dry weight and the yield was 8%. the flavonoid content was 2.353 g quercetin equivalent per 100 g of the extract. in vitro studies indicated tha ...201323909903
patterning bacterial communities on epithelial cells.micropatterning of bacteria using aqueous two phase system (atps) enables the localized culture and formation of physically separated bacterial communities on human epithelial cell sheets. this method was used to compare the effects of escherichia coli strain mg1655 and an isogenic invasive counterpart that expresses the invasin (inv) gene from yersinia pseudotuberculosis on the underlying epithelial cell layer. large portions of the cell layer beneath the invasive strain were killed or detached ...201323785519
development of a dna macroarray for simultaneous detection of multiple foodborne pathogenic bacteria in fresh chicken meat.a dna macroarray was developed to provide the ability to detect multiple foodborne pathogens in fresh chicken meat. probes targeted to the 16s rrna and genus- and species-specific genes, including fimy, ipah, prfa, and uspa, were selected for the specific detection of salmonella spp., shigella spp., listeria monocytogenes, and escherichia coli, respectively. the combination of target gene amplification by pcr and a dna macroarray in our system was able to distinguish all target bacteria from pur ...201323754709
recombinant heat shock protein 60 (hsp60/groel) of salmonella enterica serovar typhi elicits cross-protection against multiple bacterial pathogens in mice.heat shock proteins (hsps) or stress proteins are recognized as protective antigens against a wide range of bacterial diseases. conservation of hsps across different life forms also appears to contribute to the antigenicity of these proteins. due to their high sequence homology, there exists an immunological cross-recognition between different bacterial species. in the present study, we evaluated the efficacy of recombinant groel of salmonella enterica serovar typhi as a vaccine candidate agains ...201323474314
in vitro development and analysis of escherichia coli and shigella boydii azithromycin-resistant mutants.the aim of this study was to develop and analyze in vitro azithromycin (azm)-resistant mutants of escherichia coli and shigella boydii. three clinical isolates of e. coli and one s. boydii isolated from feces samples collected from children under 5 years of age with diarrhea in lima, peru were inoculated onto mueller-hinton plates containing increasing serial dilutions of azm ranging from their specific minimal inhibitory concentration (2 or 4 mg/l) to 64 mg/l. from these plates, 16 azm-resistan ...201323176550
design, synthesis and antimicrobial activity of novel benzothiazole analogs.in an attempt to design and synthesize a new class of antimicrobials, dialkyne substituted 2-aminobenzothiazole was reacted with various substituted aryl azides to generate a small library of 20 compounds (3a-t) by click chemistry. structures of the newly synthesized compounds were established on the basis of spectral data. these compounds were screened for their antibacterial activity against gram+ bacteria (staphylococcus aureus and enterococcus faecalis), gram- bacteria (salmonella typhi, esc ...201323567952
escherichia albertii, a newly emerging enteric pathogen with poorly defined properties.escherichia albertii is a newly emerging enteric pathogen that has been associated with sporadic infections among humans and birds. selected coliform isolates were screened for allelic variation in 2 housekeeping genes (lysp and mdh) specific for e. albertii. the 48 strains that were identified as e. albertii were tested for 15 virulence markers and biochemical and serogical properties. all e. albertii strains were non-motile, fermented d-glucose (with gas), d-mannitol, and d-mannose, but failed ...201323938305
further validation of the problem inventory for adolescent girls: comparing caucasian and black delinquents and nondelinquents. 20133771896
[sexually transmissible diseases in victims of sexual assault]. 20133754312
a 2,4-dichlorophenyl diazonium-based method for total bilirubin without interference from indican in uremic sera.comparison of total bilirubin quantification by a 2,4-dichlorophenyl diazonium method (2,4-dcpd) with a jendrassik-grof type of method showed excellent correlation for randomly selected sera. however, sera from uremic patients on chronic hemodialysis showed a marked positive bias for the 2,4-dcpd result as compared with the jendrassik-grof result. the mean difference was 5.3 mg/l, and resulted in about 20% of the hemodialysis patients having bilirubin values greater than 13 mg/l, the upper limit ...20133924443
a 2,4-dichlorophenyl diazonium-based method for total bilirubin without interference from indican in uremic sera.comparison of total bilirubin quantification by a 2,4-dichlorophenyl diazonium method (2,4-dcpd) with a jendrassik-grof type of method showed excellent correlation for randomly selected sera. however, sera from uremic patients on chronic hemodialysis showed a marked positive bias for the 2,4-dcpd result as compared with the jendrassik-grof result. the mean difference was 5.3 mg/l, and resulted in about 20% of the hemodialysis patients having bilirubin values greater than 13 mg/l, the upper limit ...20133924443
cranial ultrasound and clinical studies in preterm infants.serial ultrasound imaging of the brain was used to determine the ventricular index (vi), and the ratio (vr) of the vi to the cranial hemidiameter during the nursery course and first year post-term in preterm infants of less than 33 weeks gestation. twenty-nine of the infant survivors with no intracranial hemorrhage or major medical complication during their nursery course composed group 1. twenty-two survivors with intracranial hemorrhage unassociated with early ventricular dilation composed gro ...20133881581
efficacy of propranolol therapy after acute myocardial infarction related to coronary arterial anatomy and left ventricular function.the effect of the beta-adrenergic blocking agent propranolol on morbidity and mortality risk after acute myocardial infarction was studied relative to coronary anatomy and left ventricular (lv) ejection fraction in a subset of 406 patients participating in a randomized study of 3,837 patients in the beta blocker heart attack trial (bhat). median follow-up for this subset of patients was 28 months. the mortality rate was 2% (2 of 100) in patients with 2- and 3-vessel coronary artery disease takin ...20133673915
pulmonary toxoplasmoma presenting as obstructive pneumonia. 20133787527
[an outbreak of ornithosis. the military camp in porsanger in 1982]. 20133738872
[clinical picture of congenital toxoplasmosis in children hospitalized at the neonatal department of the institute of pediatrics, medical academy, in lublin]. 20133670931
thermodynamics of spectroelectrochemical electron transfer in a mesotetra sulphonated phenyl porphyrin iron(iii)-apomyoglobin complex. 20133666778
endotoxaemia in active crohn's disease. treatment with whole gut irrigation and 5-aminosalicylic acid.endotoxins in plasma were monitored during treatment in 18 patients hospitalised for acute exacerbation of crohn's disease: systemic endotoxaemia was found on admission in all but one. the patients were randomly divided into two groups: one receiving treatment with total parenteral nutrition and steroids. to decrease the absorbable endotoxin pool, the other group was additionally treated with whole gut irrigation and 5-aminosalicylic acid was added to the lavage fluid. in most of these patients ...20133732891
response of amphibian liver to external gamma irradiation. 20133659324
at least one thalamotelencephalic pathway in cartilaginous fishes projects to the medial pallium.injections of horseradish peroxidase into the medial pallium of the spiny dogfish, squalus acanthias, retrogradely labeled cells in the superficial portion of the dorsal pallium, the medial pallium and the septal area of the telencephalon, and in the posterior tubercle and posterior lateral thalamic nucleus of the diencephalon. except for the septal projection, all projections to the medial pallium are bilateral. labeled fibers could be traced from the injection site to caudal telencephalic leve ...20133627563
decisions relating to alcohol-impaired driving: an exploratory analysis.this paper focuses on an individual's decision to drive or not to drive after drinking. to evaluate this decision, a utility maximizing probabilistic choice model is specified and estimated using a sample of college students. the estimation results provide interesting insights relating to the potential effectiveness of drinking-driving countermeasures, and suggest that the most effective methods of reducing the probability of driving after drinking are those advertising and awareness campaigns t ...20133689555
[clinical significance of plasma alpha 2-plasmin inhibitor activity in obstetrics]. 20133734048
the changing demographic determinants of the growth of the extreme aged. 20133609794
the cutting diathermy and drain tracts. 20133810377
laryngeal trauma vs length of intubation.the frequency histograms of six patients' laryngographs were studied pre- and post-endotracheal intubation. the changes were correlated with the length of intubation. the post-operative hoarse voice was seen as an increase in the spread of the lower frequencies, and an increase in the fundamental frequency. the latter change was thought to be a subconscious compensation for the hoarseness. the increased lower frequency spread as measured by standard deviation was directly proportional to the len ...20133694032
[suture materials]. 20144010983
association of s-iga subunits. 20144137549
oesophageal apoplexy. 20144131036
[situational reactions in suicidologic practice].the paper is devoted to the description of suicidal manifestations in mentally normal adolescents among typical behavioural disorders characteristic of situational reactions of this age. three types of suicido-dangerous situational responses of adolescents were specified with regard to their age and auto-and heteaggressiveness ratio: reaction of deprivation, explosive reaction and reaction of auto-elimination. suicidogenic conflicts were analyzed and spheres of age-specific suicidal conflicts we ...20144072520
influence of conspecific males on the oestrous cycle of underfed female mice.female mice maintained on restricted diet (3.5, 3.0 and 2.5 gm/female/day) exhibited disturbances in the oestrous cycle which were directly related to the degree of diet restriction. females maintained on restricted diet, 2.5 gm/day, showed complete suppression of the oestrous cycle. the presence of a conspecific male was effective in maintaining normal oestrous cycles in underfed females to some extent. it is suggested that the ability of males to maintain oestrous cycle in underfed females is ...20144054221
[morbidity and health status of crews and shore personnel of the transit river fleet of the ukraine ssr]. 20144335510
[key points in the neuropathological study of idiopathic parkinsonism]. 20144897052
searchdogs bacteria, software that provides automated identification of potentially missed genes in annotated bacterial genomes.we report the development of searchdogs bacteria, software to automatically detect missing genes in annotated bacterial genomes by combining blast searches with comparative genomics. having successfully applied the approach to yeast genomes, we redeveloped searchdogs to function as a standalone, downloadable package, requiring only a set of genbank annotation files as input. the software automatically generates a homology structure using reciprocal blast and a synteny-based method; this is follo ...201424659774
stress tolerant virulent strains of cronobacter sakazakii from food.cronobacter sakazakii is considered as an emerging foodborne pathogen. the aim of this study was to isolate and characterize virulent strains of cronobacter sakazakii from food samples of bangladesh.201425723712
purification of a novel chitin-binding lectin with antimicrobial and antibiofilm activities from a bangladeshi cultivar of potato (solanum tuberosum).a new chitin-binding lectin was purified from a bangladeshi cultivar 'deshi' of potato (solanum tuberosum l.) through anion-exchange and affinity chromatographies using a chitin column. sodium dodecyl sulphate-polyacrylamide gel electrophoresis (sds-page) showed the molecular mass of the lectin as 20,000 daltons. this molecular mass was almost half of the molecular masses of chitin-binding lectins derived from other potatoes. the lectin showed both bactericidal and growth-inhibiting activities a ...201424980018
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