Publications
Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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serum igg antibody to the outer membrane proteins of campylobacter pylori in children with gastroduodenal disease. | 1989 | 2915172 | |
usefulness of culture, histology, and urease testing in the detection of campylobacter pylori. | several tests have been described which detect the presence of campylobacter pylori (cp) in the human upper gastrointestinal tract. antral biopsies from 160 endoscopies were evaluated for the presence of cp; four tests readily available to the practicing endoscopist were used: two urease tests [clotest and microtiter biopsy urease test (mbut)], hematoxylin and eosin staining, and culture. sensitivity and specificity of each was evaluated and found to be near 90%, except for culture, which was le ... | 1989 | 2916521 |
campylobacter pylori and gastric acidity. | 1989 | 2916534 | |
one-minute test for campylobacter pylori. | 1989 | 2916535 | |
[modern gastritis therapy. new pathogenetic concepts. significance of campylobacter pylori. use of bismuth compounds. report of the 16th meeting of the bayern society of gastroenterology. bad dürkheim, 21-22 october 1988]. | 1989 | 2917722 | |
serum antibody responses to the n-acetylneuraminyllactose-binding hemagglutinin of campylobacter pylori. | we recently reported that campylobacter pylori possesses a surface-associated fibrillar hemagglutinin which has an affinity for n-acetylneuraminyllactose; this hemagglutinin may function as a colonization factor for attachment to the gastric epithelium. in the present study we examined serum samples obtained from 65 c. pylori-infected individuals with gastric ulcers, duodenal ulcers, or both and from 121 asymptomatic volunteers, including 62 who were infected with c. pylori, for immunoglobulin g ... | 1989 | 2917777 |
hemagglutination activity of campylobacter pylori. | forty-five strains of campylobacter pylori isolated from gastric biopsy specimens showed distinct hemagglutination activity. the activity was partially decreased by treatment with heat, trypsin, or an alkylating agent and was inhibited by porcine gastric mucin but not by various compounds, including d-mannose. | 1989 | 2917797 |
[campylobacter pylori--an amazing discovery still of current interest]. | 1989 | 2918773 | |
in vivo susceptibility of campylobacter pylori. | campylobacter pylori infection has been associated with duodenal ulcer, gastric ulcer, and non-ulcer dyspepsia. although in vitro studies have shown that c. pylori is susceptible to most commonly used antibiotics, predictions from in vitro sensitivity studies have not led to a safe and generally effective therapy; c. pylori has proved to be very difficult to eradicate in vivo. we used the urea breath test to assess the susceptibility of c. pylori in vivo to various drugs. c. pylori was susceptib ... | 1989 | 2919580 |
campylobacter pylori in esophagus, antrum, and duodenum. a histological and microbiological study. | two hundred forty-six patients with a wide range of upper gastrointestinal tract disorders were investigated for the presence of campylobacter pylori infection in esophagus, gastric antrum, and duodenum. c. pylori was identified in 52% of patients in at least one site, and microbiological and histological techniques were used to exclude the presence of the organism. esophageal infection was not significant and is probably due to reflux. antral c. pylori was significantly associated with active g ... | 1989 | 2920650 |
campylobacter-like organisms and heterotopic gastric mucosa in meckel's diverticula. | to assess the possibility that campylobacter pylori might colonise heterotopic gastric mucosa a detailed histological review of 69 cases of meckel's diverticula resected over 17 years was undertaken. twenty three were resected incidentally while 46 were excised as the suspected cause of symptoms. gastric mucosa was found in 13 diverticula (19%), 10 from the symptomatic group and three from the incidental cases, of which eight showed active gastritis affecting the heterotopic mucosa. specific sta ... | 1989 | 2921353 |
sensitivity of campylobacter pylori to colloidal bismuth subcitrate. | 1989 | 2921366 | |
[campylobacter pylori and gastritis. association or induction?]. | 1989 | 2922375 | |
[morphologic change in campylobacter pylori associated gastritis in and following successful antibacterial therapy]. | 1989 | 2922381 | |
campylobacter pylori, hypertrophic erosive gastritis and hypoalbuminemia healed by cephalexin therapy. | 1989 | 2925040 | |
a sensitive and specific serologic test for detection of campylobacter pylori infection. | campylobacter pylori has been associated with gastritis, duodenal ulcer, gastric ulcer, and nonulcer dyspepsia. evidence that c. pylori may be the causative agent or at least a major contributory factor in peptic ulcer disease has generated intense interest in the development of reliable methods for detecting c. pylori infections. we have developed a specific and sensitive enzyme-linked immunosorbent assay (elisa) that detects serum immunoglobulin g antibodies directed against high molecular wei ... | 1989 | 2925047 |
campylobacter pylori and symptoms: is there a cause and effect relationship? | 1989 | 2925068 | |
campylobacter pylori in acquired immunodeficiency syndrome. | 1989 | 2925069 | |
campylobacter pylori virulence factors in gnotobiotic piglets. | thirty-three gnotobiotic piglets from four litters were challenged with motile and nonmotile strains of campylobacter pylori. the most motile strain, 26695, was the most virulent, with a 100% infection rate. the least motile strain, tx30a, was the least virulent, with an infection rate of only 17%. strain 60190 was weakly motile and had intermediate virulence, with an infection rate of 40%. strains recovered from piglets were more motile than the challenge strains. the challenge strains also dif ... | 1989 | 2925243 |
[histologic detection of campylobacter pylori]. | 1989 | 2466286 | |
[assessment of methods of rapid diagnosis of campylobacter pylori in duodenal ulcers]. | a study of diagnostic value of the campylobacter pylori test as well as microbiological, bacteriological and biochemical findings in 134 patients with gastroduodenal ulcer and 20 healthy persons indicates that association of the campylobacter pylori and biochemical tests are reliable and may be recommended for wide use in practical public health. | 1989 | 2469254 |
the association of campylobacter pylori with mucosal pathological changes in a population at risk for gastric cancer. | in the study of a group of 178 unselected patients (105 men, 73 women, mean age 44.5 years), from a population at high risk for gastric carcinoma, who presented with chronic dyspepsia, a minimum of 8 gastric and oesophageal biopsy specimens were taken during upper gastro-intestinal endoscopy, and examined histologically and histochemically for the presence of campylobacter pylori and other pathological lesions. gastric colonisation by c. pylori was found in 75% of men and 68.4% of women. in 90% ... | 1989 | 2470157 |
colloidal bismuth subcitrate (de-nol) inhibits degradation of gastric mucus by campylobacter pylori protease. | there is increased awareness that infection with campylobacter pylori could be a major factor in the pathogenesis of gastric disease. here, we present evidence that the extracellular protease elaborated by this bacteria, which causes degradation of gastric mucus, is inhibited by an antiulcer agent, colloidal bismuth subcitrate (cbs; de-nol). the study was conducted with c. pylori cultured from antral mucosal biopsy specimens of patients undergoing gastroscopy. the grown colonies of bacteria were ... | 1989 | 2470250 |
receptor-mediated adherence of campylobacter pylori to mouse y-1 adrenal cell monolayers. | an in vitro adherence assay was developed to study the adherence of campylobacter pylori to mammalian cells. strains of c. pylori were isolated from individuals with gastritis. these strains possessed the fibrillar n-acetylneuraminyllactose(neuraminlactose)-binding hemagglutinin (nlbh) and were found to adhere to monolayers of mouse y-1 adrenal cells. adherence was rapid, prevented by pretreatment of the y-1 cells with clostridium perfringens neuraminidase, and blocked by the neuraminlactose-con ... | 1989 | 2473033 |
campylobacter pylori infection in biopsy specimens of gastric antrum: laboratory diagnosis and estimation of sampling error. | campylobacter pylori infection was sought in 382 consecutive patients referred for upper gastrointestinal endoscopy. five antral biopsy specimens were taken from each patient: one was inserted into a clo-test to detect the urease activity of c pylori, two were sent for histological analysis where multiple sections were stained by the warthin-starry silver method, and two were sent for microbiological evaluation by gram stain and culture. a patient was deemed to be infected when c pylori was cult ... | 1989 | 2474579 |
[a method of determining campylobacter pylori in the gastric mucosa in peptic ulcer and chronic gastritis]. | an original method is described for the detection of campylobacter pylori in gastric mucosa biopsy specimens in chronic gastritis and gastroduodenal ulcers. the method is based on the detection (by a special test) of extremely high urease activity of c. pylori. the method has been employed in examinations of 211 patients. the results and prospects for the use of this technique for the detection of c. pylori in patients with gastroduodenal diseases are discussed. | 1989 | 2474707 |
[detection of campylobacter pylori in children with chronic gastritis]. | examinations of the gastric mucosa biopsy specimens from 38 children suffering from chronic gastritis have revealed campylobacter bacteria in 21 (55.3%). studies of the cultural, morphologic, and biochemical characteristics of the isolated strains have identified them as c. pylori. | 1989 | 2474708 |
comparison of rapid urease tests, staining techniques, and growth on different solid media for detection of campylobacter pylori. | thirty-nine single antral biopsies (phase 1) and 99 sets of six antral biopsies (phase 2) were collected from 132 patients, and 87 (63%) yielded positive cultures for campylobacter pylori. of several primary media tested in phase 1, tryptic soy agar and skirrow agar, each supplemented with 10% whole sheep blood, supported relatively good growth of c. pylori. in phase 2, four of the six biopsies in each set were tested with different urease systems. selective urea agar for rapid identification wa ... | 1989 | 2475524 |
[diagnostic value of various methods of detection of campylobacter pylori in patients with gastroduodenal pathology]. | 1989 | 2478756 | |
[a rapid method of diagnosis of gastric and duodenal campylobacter pylori infections]. | 1989 | 2478757 | |
the prevalence of campylobacter pylori in gastric biopsies from cancer patients. | the prevalence of campylobacter pylori (cp) in gastric biopsies from cancer patients has not been previously studied. we reviewed 112 gastric biopsies from 78 adult patients at a cancer hospital. the patients had a previous history or current diagnosis of gastric or esophageal carcinoma (26 patients), gastric lymphoma (15 patients), gastric stromal tumor (three patients), carcinoid tumor (two patients), nongastroesophageal malignancy (29 patients), or atrophic gastritis with nonhealing ulcer (th ... | 1989 | 2479007 |
the reliability of urease tests, histology and culture in the diagnosis of campylobacter pylori infection. | the accuracy of various staining techniques for immersion microscopy, of five media for culture and five urease test modalities for the detection of campylobacter pylori infection is reported. it was found that 2% urea unbuffered gel preparation is the most accurate urease test (sensitivity: 89%, specificity: 98%) but a minimal amount of 10,000 cfu/ml is necessary to observe positivity and the sensitivity of urease tests drops to 52% in patients under antimicrobial treatment. for histological di ... | 1989 | 2479086 |
an endoscopic study of campylobacter pylori in an israeli population. | 1989 | 2480339 | |
oligonucleotide probe for detection and identification of campylobacter pylori. | we have developed a novel and practical dna-rna hybridization assay for the detection and identification of campylobacter pylori in the gastric mucosa. this technique utilizes a [32p]ddatp-labeled synthetic oligonucleotide probe complementary to a nucleotide sequence present in c. pylori 16s rrna. this probe is very sensitive and reacted with all 23 strains of c. pylori tested. it is also highly specific, since there was no cross-reactivity with the heterologous organisms campylobacter coli, c. ... | 1989 | 2480360 |
[comparative study of the frequency of campylobacter pylori in duodenal and stomach ulcers and chronic gastritis using the urease test and histologic staining]. | 1989 | 2480691 | |
isolation of campylobacter pylori in patients with non-ulcer dyspepsia. | 1989 | 16312293 | |
in vitro antibacterial activity of rifaximin against campylobacter pylori (campylobacter pyloridis). | 1989 | 16312378 | |
colloidal bismuth subcitrate (de-nol) and tinidazole healed duodenal ulceration with a low relapse rate due to elimination of campylobacter pylori. | 1989 | 16312662 | |
acridine orange fluorescence, campylobacter pylori, and chronic gastritis. | endoscopic gastric biopsy specimens from 230 consecutive patients in a north liverpool district were histologically studied by routine light microscopy and ultraviolet fluorescence after acridine orange staining. eighty patients with chronic gastritis were further studied with regard to type of gastritis and its activity, presence of campylobacter pylori (cp), and degree of colonization of the gastric mucosa. miscellaneous gastritis, gastric ulcers, erosions, neoplasms, and histologically normal ... | 1990 | 1689506 |
[a method of isolating campylobacter pylori from the gastrointestinal mucosa]. | 1990 | 1692368 | |
[diagnosis of campylobacter pylori in chronic gastritis, gastric ulcer and duodenal ulcer (review of the literature)]. | 1990 | 1695273 | |
[diagnosis of campylobacter pylori based on the level of urea in the gastric juice]. | comparison of urea levels in 3 portions of gastric juice, obtained on an empty stomach, basal, and stimulated, from 28 patients, c. pylori carriers, and 20 patients without c. pylori carriership, has shown that the presence of this bacterium in the gastric mucosa is related not so much with a decrease in the absolute level of urea in the portion collected on an empty stomach but mostly with changes in this parameter in three portions of gastric juice collected in succession. decreased urea level ... | 1990 | 1695282 |
comparison of four stains and a urease test for rapid detection of helicobacter pylori in gastric biopsies. | gastric biopsies were obtained from 125 subjects to compare detection of helicobacter pylori by culture, a rapid urease test and histopathologic examination using haematoxylin-eosin, gram, giemsa, warthin-starry silver and acridine orange stains. helicobacter pylori was isolated from 39 specimens. acridine orange and giemsa were the most sensitive stains, detecting 85% and 79% of positive specimens respectively. all stains showed high specificity (97-100%). the sensitivity and specificity of the ... | 1990 | 1695573 |
comparison of culture and histology for the identification of helicobacter pylori in endoscopic biopsies. | the aim of the study was to compare culture with microscopic examination of haematoxylin and eosin stained tissue sections in the identification of helicobacter pylori in gastric antral mucosa. duplicate gastric antral biopsies from 89 patients were cultured and examined histologically for h pylori. h pylori was cultured in 46 cases (51%) and identified histologically in 63 (71%). results from the two tests concurred in 63 cases (71%). the presence of h pylori was strongly correlated with histol ... | 1990 | 1697451 |
use of dna restriction endonuclease digest and ribosomal rna gene probe patterns to fingerprint helicobacter pylori and helicobacter mustelae isolated from human and animal hosts. | variation amongst strains of helicobacter pylori and helicobacter mustelae was examined by dna restriction endonuclease digestion and rrna gene patterns generated using a non-radioactive probe. chromosomal dna was extracted from 30 cultures of h. pylori from human, rhesus monkey and pig gastric mucosa, and from three h. mustelae isolates from ferret gastric mucosa. dna fingerprinting with hae iii and hind iii showed h. mustelae was relatively homogeneous but revealed genomic heterogeneity within ... | 1990 | 1698260 |
detection of antibodies to helicobacter pylori cell surface antigens. | serum igg antibodies of helicobacter pylori were detected in single-dilution elisa using glycine extracted material. among 148 endoscopy patients 59% displayed antibodies; as expected, a higher occurrence (90%) was found in patients with positive gastric culture for h. pylori than in culture negative patients (37%). among 68 blood donors the frequency of h. pylori antibodies was 28%. in 73 children less than 15 years of age examined for unrelated disorders the occurrence was 4%. by immunoblottin ... | 1990 | 1699265 |
a spiral microorganism in the stomach of pigs. | light and electron microscopic and microbiologic evaluations were performed on mucosa of stomachs from 120 healthy slaughtered pigs. helicobacter pylori was not found, but a tightly spiralled bacterium, not previously described, was seen in histological sections and/or in carbol fuchsin stained smears in 13 (10.8%) stomachs. in paraffin sections stained with carbol fuchsin, the bacteria were seen in the mucus of the lumen of the antral pits and in the mucosa surface within and beneath the mucus. ... | 1990 | 1700535 |
comparison of sensitivity and specificity of three different methods for the detection of helicobacter pylori infection. | 1990 | 1701286 | |
superior stain for helicobacter pylori using toluidine o. | 1990 | 1702103 | |
different effect of helicobacter pylori on the human gastric antral and body mucosal intracellular mucin. | to elucidate the role of helicobacter pylori infection in the pathogenesis of gastric ulcer, we investigated the intracellular mucin content by measuring the periodic acid-schiff-alcian blue (pas-ab)-stained substances, by means of computer, in the biopsy sample of gastric mucosa from patients with and without h. pylori infection. in the antral mucosa the intracellular pas-ab-stained mucin content was significantly smaller in patients with infection than in patients without infection, whereas in ... | 1990 | 1702231 |
direct gram stain and urease test to detect helicobacter pylori. | antral biopsies were obtained by gastrointestinal endoscopy on 143 adult patients with dyspeptic symptoms of gastritis or peptic ulcer disease. a direct gram stain and a direct urease test were performed on each biopsy in addition to culture. forty-three biopsies (30%) were considered positive for helicobacter pylori based on culture or histologic examination, or both. thirty-one biopsies (72% sensitivity) were positive for both direct tests, whereas 95 of 100 negative cultures were negative for ... | 1990 | 1703938 |
direct detection and amplification of helicobacter pylori ribosomal 16s gene segments from gastric endoscopic biopsies. | helicobacter pylori is an organism thought to play an important causative role in gastritis and peptic ulcer diseases. we have designed an rna dot blot assay for the detection of h. pylori, using as probe a synthetic oligonucleotide complementary to its 16s rrna. we have also used oligonucleotide primers, complementary to conserved sequences within bacterial ribosomal 16s genes, to amplify a h. pylori ribosomal 16s dna fragment via the polymerase chain reaction (pcr). after determining the dna s ... | 1990 | 1703940 |
rapid diagnosis of campylobacter pylori infection by urea test paper. | antral biopsy specimens from 106 patients were examined by culture, gram stain and silver stain for campylobacter pylori. biopsies were also examined by a urea test paper test (utpt). of 106 patients studied c. pylori was detected in 68 (64.2%) by gram stain, silver stain and culture. the utpt was positive in 63 (59.4%) specimens. five had false negative results using the utpt with no false positive subjects. thus, utpt has a sensitivity of 92.6% (63/68) and a specificity of 100%. of the 63 spec ... | 1990 | 1717032 |
hypothesis: helicobacter pylori, urease, mucus, and gastric ulcer. | ammonia, released in the gastric mucosa by the action of helicobacter pylori urease on transuded plasma urea, curtails the biosynthesis of mucus and/or causes the mucus to be disassembled at the mucosal surface. these changes facilitate colonisation by h pylori and may promote gastric ulcer formation. | 1990 | 1967668 |
metronidazole-resistant helicobacter pylori. | 1990 | 1968548 | |
helicobacter pylori, mucus, and gastric ulcer. | 1990 | 1969087 | |
prevalence of campylobacter pylori as demonstrated by histology or clo-test in different types of gastritis. a study in 5 clinically predefined groups of patients. | the prevalence of campylobacter pylori infection as detected by histology was studied in 5 predefined groups of patients. the associated histologic and endoscopic findings were registered. validity of clo-test was tested against the histologic detection. the following groups of patients were studied: a) non-ulcer dyspepsia (defined by one or all of three symptoms: heartburn, nausea/inappetence, halitosis/belching) b) control group (no specific symptoms, no ulcer, no history of gastric surgery) c ... | 1990 | 1969152 |
metronidazole resistance in helicobacter pylori. | 1990 | 1970050 | |
helicobacter pylori acid resistance. | 1990 | 1971083 | |
cure of duodenal ulcer associated with eradication of helicobacter pylori. | 50 patients with intractable duodenal ulcer were randomly assigned to 4 weeks of treatment with colloidal bismuth subcitrate (cbs) alone (26 patients) or with amoxicillin and metronidazole (24 patients). 5 patients (all on triple therapy) withdrew because of side-effects. in 17 of the 45 patients who completed the treatment, helicobacter pylori was eradicated, and there was no ulcer relapse during the first 12 months of follow-up. the ulcer relapse rate was significantly higher (17 of 21 [89%]) ... | 1990 | 1971318 |
in vitro killing of helicobacter pylori with photodynamic therapy. | 1990 | 1971363 | |
helicobacter pylori and hiv infection. | 1990 | 1972223 | |
cure of peptic ulcer associated with eradication of helicobacter pylori. | 1990 | 1972523 | |
vaccination against helicobacter pylori urease. | 1990 | 1973509 | |
cure of duodenal ulcer after eradication of helicobacter pylori. | eighty-two patients, whose duodenal ulcers were recurrent or resistant to h2-receptor antagonist therapy, were entered in a treatment protocol of ranitidine followed by a four-week "triple therapy" course to eradicate helicobacter pylori (hp) infection. the triple therapy consisted of colloidal bismuth subcitrate, tetracycline and metronidazole. duodenal ulcer healed in all 78 patients available for endoscopy and h. pylori infection was shown to be eliminated in 75 patients (96%) at rebiopsy fou ... | 1990 | 1974027 |
mixed gastric infection by gastrospirillum hominis and helicobacter pylori. | 1990 | 1975013 | |
antibodies to helicobacter pylori in hiv infection. | 1990 | 1975069 | |
treatment of helicobacter pylori positive duodenal ulcers. | 1990 | 1975930 | |
gastroduodenal pathology and helicobacter pylori. third workshop of the european helicobacter pylori study group. proceedings. | 1990 | 1977429 | |
therapy in helicobacter pylori infection. | 1990 | 1978187 | |
pathogenesis and therapy of peptic ulcer disease. | the epithelial cells of the stomach and duodenum are normally protected from the damaging effects of acid and pepsin by a balancing mechanism of mucosal resistance. if an imbalance occurs, peptic ulcer may result. traditional teaching has emphasized the importance of acid (and pepsin) as the cause of this imbalance; however, it is clear that acid and pepsin are not the only important factors in the pathogenesis of peptic ulcer. more recent investigative efforts have been directed at what constit ... | 1990 | 1978840 |
helicobacter pylori and metronidazole resistance. | 1990 | 1978897 | |
sydney classification for gastritis and helicobacter pylori. | 1990 | 1978898 | |
inhibition of helicobacter pylori by acetohydroxamic acid. | 1990 | 1979397 | |
evaluation of urease test, gram stain, culture, and histology in the detection of campylobacter pylori. | to evaluate the commonly available tests for detection of campylobacter pylori infection in the human stomach, we prospectively performed endoscopy and biopsy from the antrum of the stomach in 121 consecutive patients. four tests, including the urease test, gram stain, culture, and the hematoxylin and eosin (h & e) stain were used to detect the presence of c. pylori. a c. pylori positive was defined by a positive culture or positive results in two of the other three tests. the sensitivity of the ... | 1990 | 1981231 |
epidemiology and treatment of gastric campylobacter pylori infection: more questions than answers. | two-hundred and ten consecutive patients undergoing routine gastroscopy were additionally investigated for evidence of campylobacter pylori (c.p.). 106 patients were positive in one or more tests: 99.1% using a rapid urease detecting test (clo-test), 80.2% histology, 78.3% cytology and 60% culture. we found no difference between the clo-test results from biopsies taken from different parts of the stomach in individual patients. c.p. was found in 100% of patients with significant chronic antral g ... | 1990 | 1982107 |
determinants of acid secretion. | acid secretion is regulated by hormonal factors acting peripherally and centrally, as well as neural factors. gastrin and histamine are the two most important peripheral hormonal stimulants, while the vagus is the predominant nerve affecting acid secretion. meal related acid secretion occurs in three phases: cephalic, gastric and intestinal. acid secretion is stimulated in the first two phases while it is inhibited in the intestinal phase. proteins are potent acid stimulants but carbohydrates an ... | 1990 | 1982628 |
site-and cytoprotective drugs in the short-term treatment of peptic ulcer. what is their current role? | many endoscopically controlled comparisons with h2-blockers have widely documented that site- and cytoprotective drugs constitute effective and safe agents for the short-term treatment of gastric and duodenal ulcer. their efficacy however, is counter-acted by the need for multiple daily administration which requires greater patient compliance. due to its ability to eradicate helicobacter pylori (hp) from the gastric antrum and retard relapses, colloidal bismuth may be the first choice anti-ulcer ... | 1990 | 1983422 |
helicobacter pylori and gastric carcinoma. | a retrospective study was performed on gastric carcinomas to establish the prevalence of helicobacter pylori infection in gastric epithelium adjacent to the tumour. a total of 105 carcinomas were studied. the overall prevalence of helicobacter pylori infection was 59%. the prevalence in different age cohorts from patients with gastric carcinoma was compared with that in patients suffering from non-ulcer dyspepsia and, based on serological testing, with that in healthy blood donors. the presence ... | 1990 | 2076886 |
[campylobacter pylori in gastroduodenal pathology]. | 1990 | 2084340 | |
synergism between clindamycin and colloidal bismuth subcitrate against helicobacter (campylobacter) pylori in vitro. | a combination of clindamycin and colloidal bismuth subcitrate was evaluated for synergistic inhibition of helicobacter pylori employing the agar dilution method. a total of 47 clinical isolates of helicobacter pylori were examined. synergistic interaction was observed in 36%, additive behaviour in 64% of the strains. no antagonism could be detected. | 1990 | 2085373 |
[enzyme-linked immunosorbent assay for the serodiagnosis of campylobacter pylori infection]. | antibody activities to campylobacter pylori in serum were estimated by an enzyme-linked immunosorbent assay (elisa) to crude antigens, prepared by sonication of whole organisms obtained from bacterial culture in 100 patients with chronic gastritis. significantly raised serum igg antibody activities to c. pylori was found in colonised patients with gastritis, especially in patients with active gastritis. high activities were also found beyond the age of 30. in 6 patients cleared of c. pylori with ... | 1990 | 2086012 |
activity of cefixime against helicobacter pylori and affinities for the penicillin-binding proteins. | cefixime induced the formation of rounded cells from the spiral bacillary form of helicobacter pylori at the mic or less. three main penicillin-binding proteins, called a, b and c, were separated from h. pylori. cefixime had the strongest affinity to penicillin-binding protein b. the binding of cefixime to this protein may induce the formation of rounded h. pylori cells. | 1990 | 2088199 |
[characteristics of helicobacter (campylobacter) pylori infection in our field]. | the presence of helicobacter pylori in the stomach in patients with clinical signs of gastroduodenal disease and its possible relationship with several clinical, endoscopic and anatomopathologic characteristics of the illness were prospectively evaluated in 359 patients. h. pylori was isolated from 388 samples in 216 patients (60% of colonization). in patients with endoscopic and, or, anatomopathologic evidence of gastroduodenal alterations the microorganism was isolated in 67% of the instances ... | 1990 | 2089203 |
detection of helicobacter pylori in gastric brushings. | 1990 | 2091356 | |
[t-lymphocytes of the gastric mucosa in peptic ulcer]. | chronic ulcer edges and pylorus of 6 stomachs removed because of ulcer and 10 biopsies of the stomach pylorus from patients with duodenal ulcer were studied. t-helpers and t-suppressors (cytotoxic) were revealed by the indirect three-step immunoperoxidase method with the use of monoclonal antibodies okt-4 and okt-8, respectively. t-suppressors (cytotoxic) prevailed among interepithelial gastric lymphocytes in both normal conditions and ulcer. t-helpers dominated in the mucosa tunica propria. the ... | 1990 | 2091578 |
[detection of campylobacter pylori in gastric mucosa--relation to gastroscopy findings and degree of gastritis]. | in 862 unselected gastroscopies we could confirm the high percentage of campylobacter pylori infection in the antral gastric mucosa strongly associated with chronic superficial gastritis and active inflammatory signs. significant correlation with age concerned the normal findings only. in patients with duodenal ulcers we found in 91% gastritis and in 88% campylobacter pylori in antral mucosa. a small group with duodenal ulcers was campylobacter pylori-negative as well as without gastritis signs. ... | 1990 | 2091669 |
comparison of four different methods for detection of helicobacter pylori from gastric biopsies. | helicobacter pylori are commonly found colonizing the gastric mucosa of different populations. its presence may be important in the pathogenesis of gastritis and peptic ulcer disease. the detection rates vary widely depending upon the diagnostic methods applied. in this study, multiple gastric biopsies were taken from the fundal and antral mucosa of 25 patients during endoscopy. in one patient, the procedure was repeated about two months after the initial biopsy. a total of 52 sets of specimens ... | 1990 | 2091902 |
relative merits of various rapid biopsy urease tests for diagnosis of helicobacter pylori (campylobacter pylori). | three rapid urease tests, i.e., liquid urea broth containing phenol red as indicator, liquid urea broth containing bromothymol blue as indicator and clo gel were compared in 109 patients of dyspepsia for the diagnosis of campylobacter pylori (helicobacter pylori) infection. mean time taken for positive reaction in liquid broth with phenol was 3 minutes (range 0.6 to 5.3 minutes) with bromothymol blue was 3.5 minutes (range 0.4 to 5.5 minutes) while with clo gel it was 101 minutes (range 11-261 m ... | 1990 | 2092020 |
unusual features of helicobacter (campylobacter) pylori--associated gastritis in india. a study of 200 cases. | helicobacter (campylobacter) pylori has been cultured from the antral biopsies of 85-90% of patients of gastritis, gastric ulcer and duodenal ulcer at different centres. studies conducted all over the world have firmly implicated this organism in the aetiology of active superficial gastritis and recurrences of duodenal ulcer. two hundred patients with upper abdominal pain, distension, vomiting and/or haemetemesis were subjected to ogd scopy. in 163 of these patients there was endoscopic evidence ... | 1990 | 2092022 |
association of peptic ulcer with helicobacter pylori and the recurrence rate. a three year follow-up study. | helicobacter pylori is associated with 70-100% of peptic ulcers. relapse of infection has been shown to cause recurrences of ulcers in a large number of studies. we diagnosed 137 cases of peptic ulcer (121 du; 16 gu) during a 3 year period. of these, 117 were positive for h pylori. sixty six of the 117 cases staying in the vicinity of the hospital were followed up for a minimum period of 3 months upto a maximum period of 3 years. in 91 examinations there was relapse of h pylori infection and ulc ... | 1990 | 2092024 |
relapse of helicobacter pylori infection after different treatment regimens. a 3-month follow-up study. | helicobacter pylori infection of gastric antrum is associated with a majority of cases of peptic ulcer (70-100%). studies have shown that when this organism is eradicated, the recurrence of ulcer falls to less than one-third of those in whom the infection persists or relapses. monotherapy with bismuth salts, tinidazone or amoxycillin has been shown to result in early relapse and recurrence of ulcers. however, dual or triple therapy regimens are more effective. we conducted a randomised controlle ... | 1990 | 2092026 |
does helicobacter pylori play a role in the pathogenesis of peptic ulcer? part i: no. helicobacter pylori is a commensal in the stomach. | 1990 | 2092033 | |
does helicobacter pylori play a role in the pathogenesis of peptic ulcer? part ii. yes, helicobacter pylori is a pathogenetic factor in peptic ulcer. | 1990 | 2092034 | |
[biochemical, physiological, and enzymatic study of 78 strains of helicobacter (campylobacter) pylori isolated from gastroduodenal biopsies]. | a biochemical, physiological and enzymatic study of 78 c. pylori strains isolated from gastroduodenal biopsies is reported. all strains were positive in the oxidase, catalase and urease tests. 97.4% produced sh2 in the lead acetate band and 79.4% showed beta-hemolytic activity in sheep blood agar. in the antibiotic selection tests, c. pylori was characterized to be resistant to nalidixic acid and sensitive to cefalotin . the enzymatic study demonstrated the presence of acid and alkaline phosphat ... | 1990 | 2094388 |
[comparative study of campylobacter pyloridis and campylobacter jejuni under electron microscope]. | specimens were made by preparing the ultrathin sections after negative staining and ruthenium red staining. the specimens were observed under electron microscope. results revealed that the shapes of campylobacter pyloridis (cp) and c. jejuni (cj) were similar, but distinctive differences in their structures were observed. cp had one to five sheathed flagella at one end with bulbous tips. cj had only one unsheathed flagellum on each end without a bulbous tip. the cell body of cp was longer than t ... | 1990 | 2094635 |
[helicobacter pylori and gastro-duodenal pathology]. | helicobacter pylori (hp) were found in 878 (73%) of 1205 patients undergoing upper g-i endoscopy with multiple biopsies for gastroduodenal diseases. hp were present in similar percentages among patients with active (89%) or healed (81%) peptic ulcer as well as in non ulcerous dyspeptics affected with gastritis (85%). 96% of active chronic gastritis were infected by hp as compared with 55% of quiescent gastritis. antral gastritis was more frequently active in patients with ulcer diseases (76%) th ... | 1990 | 2094841 |
eradication of campylobacter pylori and recurrence of duodenal ulcer. a six-month follow-up study. | fifty-four patients were studied, 41 men and 13 woman, aged 26-76 years, suffering from duodenal ulcer that healed 4-8 weeks after colloidal bismuth subcitrate therapy (360 mgr twice a day). all patients underwent endoscopy before treatment, 4-8 weeks and 6 months later. biopsy was taken for campylobacter pylori (c.p.) detection by urease test. all patients were c.p. positive initially. the organisms were eradicated in 36/54 patients (67%) at the end of therapy. ulcer healing was obtained after ... | 1990 | 2095099 |
adherence of helicobacter pylori cells and their surface components to hela cell membranes. | four helicobacter pylori strains were used to develop in vitro methods to assess adherence to hela cells. using direct detection by microscopy, adhesion scores increased with the initial bacteria-to-cell ratio. the urease method assessed h. pylori bound to hela cells by their urease activity. the percentage of the original inoculum adhering to hela cells remained constant for initial ratios from 10(2) to 10(5) bacteria per cell. an elisa using anti-h. pylori serum assessed whole bacteria or comp ... | 1990 | 2097496 |
helicobacter pylori--our knowledge is growing. | 1990 | 2099416 |