Publications

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epidemiology of polyparasitism with taenia solium, schistosomes and soil-transmitted helminths in the co-endemic village of malanga, democratic republic of congo.helminth co-infections are common in sub-saharan africa. however, little is known about the distribution and determinants of co-infections with taenia solium taeniasis/cysticercosis. building on a previous community-based study on human cysticercosis in malanga village, we investigated co-infections with taenia solium, soil-transmitted helminths (sths) and schistosoma spp and associated risk factors in a random subsample of 330 participants. real time pcr assays were used to detect dna of soil-t ...201728336269
advances in neglected tropical disease vaccines: developing relative potency and functional assays for the na-gst-1/alhydrogel hookworm vaccine.a new generation of vaccines for the neglected tropical diseases (ntds) have now advanced into clinical development, with the na-gst-1/alhydrogel hookworm vaccine already being tested in phase 1 studies in healthy adults. the current manuscript focuses on the often overlooked critical aspects of ntd vaccine product development, more specifically, vaccine stability testing programs. a key measure of vaccine stability testing is "relative potency" or the immunogenicity of the vaccine during storag ...201728192438
diagnosing polyparasitism in a high-prevalence setting in beira, mozambique: detection of intestinal parasites in fecal samples by microscopy and real-time pcr.many different intestinal parasite species can co-occur in the same population. however, classic diagnostic tools can only frame a particular group of intestinal parasite species. hence, one or two tests do not suffice to provide a complete picture of infecting parasite species in a given population. the present study investigated intestinal parasitic infections in beira, mozambique, i.e. in the informal settlement of inhamudima. diagnostic accuracy of five classical microscopy techniques and re ...201728114314
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