Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| [epidemiology and drug resistance of the pathogenic microbes in the complicated infection of hematological malignancies]. | to investigate the epidemiological characteristics and drug resistance profile of the infection in patients with hematological malignancies. | 2004 | 15308008 |
| relationship between oral motor dysfunction and oral bacteria in bedridden elderly. | the purpose of this study was to analyze the relationship between oral bacterial colonization and oral motor dysfunction. | 2004 | 15316545 |
| community-acquired infection due to stenotrophomonas maltophilia: a rare cause of meningitis. | 2004 | 15325602 | |
| bacterial communities and enzyme activities of pahs polluted soils. | three soils (i.e. a belgian soil, b-bt, a german soil, g, and an italian agricultural soil, i-bt) with different properties and hydrocarbon-pollution history with regard to their potential to degrade phenanthrene were investigated. a chemical and microbiological evaluation of soils was done using measurements of routine chemical properties, bacterial counts and several enzyme activities. the three soils showed different levels of polycyclic aromatic hydrocarbons (pahs), being their contamination ... | 2004 | 15331267 |
| stenotrophomonas maltophilia peritonitis in capd patients: susceptibility to antibiotics and treatment outcome: a report of five cases. | 2004 | 15335157 | |
| increase in methicillin-resistant staphylococcus aureus acquisition rate and change in pathogen pattern associated with an outbreak of severe acute respiratory syndrome. | an outbreak of severe acute respiratory syndrome (sars) occurred in our 22-bed intensive care unit (icu; prince of wales hospital, hong kong, hksar, china) from 12 march to 31 may 2003, when only patients with sars were admitted. this period was characterized by the upgrading of infection control precautions, which included the wearing of gloves and gowns all the time, an extensive use of steroids, and a change in antibiotic prescribing practices. the pattern of endemic pathogenic organisms, the ... | 2004 | 15356814 |
| central venous catheter-related bacteremia due to gram-negative bacilli: significance of catheter removal in preventing relapse. | to study the characteristics of catheter-related, gram-negative bacteremia (gnb) and the role of central venous catheter (cvc) removal. | 2004 | 15357155 |
| microbiological identification in cystic fibrosis patients with cftr i1234v mutation. | recurrent and chronic bacterial pulmonary infection is the major cause of morbidity and mortality in cystic fibrosis (cf). over 6 months, 72 sputa or oropharyngeal samples were examined from 36 arab bedouin cf patients attending hamad general hospital, doha, qatar. more than 100 pathogens were isolated, mostly haemophilus influenzae, staphylococcus aureus and pseudomonas aeruginosa. unusual pathogens included stenotrophomonas maltophilia, acaligenes xylosoxidans and mycobacterium abscessus. it i ... | 2004 | 15357563 |
| lethal pulmonary hemorrhage caused by a fulminant stenotrophomonas maltophilia respiratory infection in an acute myeloid leukemia patient. | stenotrophomonas maltophilia (sm) pneumonia in immunocompromized hosts is an increasingly common nosocomial infection. even though resistant to multiple antimicrobials, this gram-negative bacteria usually does not present with a fulminant course leading to a fatal hemorrhagic respiratory infection in neutropenic patients. we report here the case of a 63-year-old woman treated by intensive chemotherapy for acute myeloid leukemia (aml) who presented while severely neutropenic and thrombocytopenic ... | 2004 | 15360016 |
| stenotrophomonas maltophilia infection in patients receiving continuous ambulatory peritoneal dialysis. | stenotrophomonas maltophilia is a gram-negative bacillus that has become increasingly recognized as an important nosocomial pathogen, particularly in individuals with severe debilitation or immunosuppression. s. maltophilia is also characterized by its resistance to multiple antibiotics. s maltophilia peritonitis in capd (continuous ambulatory peritoneal dialysis) patients is associated with a poor prognosis and loss of capd catheter. no report concerning this entity has been presented in korea. ... | 2004 | 15366641 |
| improved laboratory diagnosis of bacterial and fungal infections in patients with hematological malignancies using pcr and ribosomal rna sequence analysis. | during october 1999 to november 2000, 98 blood culture specimens from the same number of febrile episodes originating from 49 patients with hematological malignancies were examined for the presence of eubacteria and fungi based on 16s rrna gene and the 5.8, 18 and 28s rrna combined with in vitro pcr amplification and sequencing, in addition to conventional blood culture laboratory techniques. nineteen of the samples were associated with positive blood cultures. eubacterial (16s rrna) pcr detecte ... | 2004 | 15370218 |
| inactivation of macrolides by producers and pathogens. | inactivation, one of the mechanisms of resistance to macrolide, lincosamide and streptogramin (mls) antibiotics, appears to be fairly rare in clinical isolates in comparison with target site modification or efflux. however, inactivation is one of the major mechanisms through which macrolide-producing organisms avoid self-damage during antibiotic biosynthesis. the inactivation mechanisms for mls antibiotics in pathogens are mainly hydrolysis, phosphorylation, glycosylation, reduction, deacylation ... | 2004 | 15379733 |
| [tricuspid infective endocarditis caused by stenotrophomonas maltophilia in a patient without risk factors]. | 2004 | 15388041 | |
| nosocomial stenotrophomonas maltophilia cross-infection: three cases in newborns. | increased nosocomial stenotrophomonas maltophilia infection rates in newborns, especially in recent years, are a significant cause for concern. these cases are the second case group in the literature to have been identified as nosocomial cross-infection with s. maltophilia in neonates. | 2004 | 15454897 |
| stenotrophomonas maltophilia as a nosocomial pathogen. | the aim of this study was to investigate the molecular epidemiology of stenotrophomonas maltophilia in a university hospital in turkey. thirty nine clinical isolates were collected from 37 patients and one from an environmental source between 1998 and 2001. susceptibility to 11 antimicrobials was studied. the isolates were categorised into six groups: a through f. trimethoprim sulfamethoxazole was the most active agent against the tested isolates. genotypic analysis by pulsed-field gel electroph ... | 2004 | 15460530 |
| beta-lactamase inhibitors: evolving compounds for evolving resistance targets. | the many and diverse beta-lactamases produced by bacteria, particularly by gram-negative pathogens, are increasingly posing a serious threat to the clinical utility of beta-lactams. first-generation inhibitors (clavulanic acid, sulbactam, tazobactam) focus on ambler class a enzymes. however, recent structural upgrades of class a beta-lactamases (e.g. tem, shv) have extended their spectrum (extended-spectrum beta-lactamases and carbapenemases [sme, nmc-a, imi-1]) and have brought about the possib ... | 2004 | 15461559 |
| antibiograms of resistant gram-negative bacteria from scottish cf patients. | over a 19-month pilot phase, 93 multiply resistant gram-negative isolates from scottish cystic fibrosis patients were sent to a referral laboratory for further investigation. | 2004 | 15463901 |
| analysis of tnt (2,4,6-trinitrotoluene)-inducible cellular responses and stress shock proteome in stenotrophomonas sp. ok-5. | in this study, the cellular responses of stenotrophomonas sp. ok-5 to explosive 2,4,6-trinitrotoluene (tnt) have been extensively analyzed. the stress shock proteins, which might contribute to enhancing cellular resistance to tnt-mediated toxicity, were induced at different concentrations of tnt used as a substrate for cell culture of stenotrophomonas sp. ok-5 capable of utilizing tnt. proteomic analysis for 2-de of soluble protein fractions from the culture of ok-5 exposed to tnt demonstrated a ... | 2004 | 15486709 |
| aggregation-based cooperation during bacterial aerobic degradation of polyethoxylated nonylphenols. | three bacterial strains were isolated from activated sludge samples of two treatment plants receiving domestic and industrial wastewaters containing polyethoxylated nonylphenols. one strain (va160) was isolated on rich medium, and the other two (bcal1 and bcal2) on mineral medium containing two industrial mixtures of nonylphenol ethoxylates as the sole carbon source. strain va160 was a gram-positive, spore forming, filamentous bacterium, producing aggregates during growth in liquid medium. on th ... | 2004 | 15501654 |
| pitfalls of polymyxin antimicrobial susceptibility testing of pseudomonas aeruginosa isolated from cystic fibrosis patients. | with their potent activity against gram-negative bacteria, the polymyxins are important alternative antibiotics for cystic fibrosis (cf) patients. a retrospective evaluation of polymyxin activity against 6001 pseudomonas aeruginosa, 150 achromobacter xylosoxidans and 506 stenotrophomonas maltophilia cf isolates was initiated. in addition, we looked at how polymyxin susceptibility testing was affected by the testing method (agar dilution versus microdilution), the agent (polymyxin e versus polymy ... | 2004 | 15509615 |
| association between stenotrophomonas maltophilia and lung function in cystic fibrosis. | stenotrophomonas maltophilia (sm) is a gram-negative non-fermenting bacteria cultured from the sputum of patients with cystic fibrosis (cf). to date, no information is available regarding the effect of this organism on lung function in cf. | 2004 | 15516471 |
| evaluation of three molecular typing techniques for nonfermentative gram-negative bacilli. | to evaluate three different dna techniques for typing nonfermentative gram-negative bacilli isolated from latin american hospitals. | 2004 | 15518027 |
| topoisomerases mutations and fluoroquinolone resistance in stenotrophomonas maltophilia. | 2004 | 15519490 | |
| in vitro antimicrobial activity of gatifloxacin compared with other quinolones against clinical isolates from cancer patients. | owing to the predominance of gram-positive pathogens in neutropenic cancer patients, newer generation quinolones with an expanded gram-positive spectrum and enhanced potency, may have a role to play for prophylaxis and/or empiric therapy in such patients. the in vitro activity of gatifloxacin was compared with that of ciprofloxacin, levofloxacin and trovafloxacin against 848 recent clinical isolates from cancer patients. against gram-positive organisms, gatifloxacin was the most active agent tes ... | 2004 | 15523180 |
| bacterium-based no2- biosensor for environmental applications. | a sensitive no2- biosensor that is based on bacterial reduction of no2- to n2o and subsequent detection of the n2o by a built-in electrochemical n2o sensor was developed. four different denitrifying organisms lacking no3- reductase activity were assessed for use in the biosensor. the relevant physiological aspects examined included denitrifying characteristics, growth rate, no2- tolerance, and temperature and salinity effects on the growth rate. two organisms were successfully used in the biosen ... | 2004 | 15528518 |
| interactions in biofilms between listeria monocytogenes and resident microorganisms from food industry premises. | twenty nine bacterial strains were grown as binary culture biofilms with listeria monocytogenes to assess their influence on the settlement of the latter on stainless steel coupons. most of the strains had been isolated from food processing plants after cleaning and disinfection and were tentatively identified by the apilab plus 3.3.3 database (biomerieux). sixteen of them decreased l. monocytogenes biofilm colony forming units (cfu) counts. three strains, bacillus sp. ccl 9 an unidentified gram ... | 2004 | 15541798 |
| pseudoxanthomonas mexicana sp. nov. and pseudoxanthomonas japonensis sp. nov., isolated from diverse environments, and emended descriptions of the genus pseudoxanthomonas finkmann et al. 2000 and of its type species. | three mesophilic bacteria (strains amx 26b(t), ur374_02 and 12-3(t)) isolated respectively from an anaerobic digester, human urine and urban riverside soil were characterized. cells were gram-negative, motile, non-sporulating, straight to curved rods with one polar flagellum and had a strictly respiratory metabolism with o(2) as the preferential terminal electron acceptor. phylogenetic analysis based on 16s rrna gene sequences revealed that all strains clustered within the xanthomonadaceae branc ... | 2004 | 15545466 |
| inhibition of the reattachment of young adult zebra mussels by single-species biofilms and associated exopolymers. | to determine the effects of single-species bacterial films and their associated extracellular products on the reattachment of young adult zebra mussels. | 2004 | 15546415 |
| multiresistant stenotrophomonas maltophilia tunneled cvc-related sepsis, treated with systemic and lock therapy. | in the last decade, a remarkable increase in the incidence of nosocomial gram-negative infections has been observed. these pathogens represent a substantial problem in clinical practice, due to the high resistance profile of most commonly used antibiotics. this phenomenon is surely a co-factor that exposes these susceptible patients to infections caused by selected pathogens like multiresistant gram-negative rods. a typical example is represented by vap (ventilator-associated pneumonia) sustaine ... | 2004 | 15565919 |
| implantable venous port-related infections in cancer patients. | to evaluate the characteristics of implantable venous port-related infections in patients with malignancies. | 2004 | 14727170 |
| case-control study of stenotrophomonas maltophilia acquisition in cystic fibrosis patients. | the aims of this case-control study were to describe the characteristics of cystic fibrosis (cf) patients who isolated stenotrophomonas maltophilia in sputum, to determine risk factors for acquisition, to assess persistence of the organism and clinical outcomes postacquisition. data were collected from 1991-1999. cf patients and controls (who had never isolated s. maltophilia) were matched for age (+/- 1 yr), sex and forced expiratory volume in one second (+/- 10%). data were collected from the ... | 2004 | 14738239 |
| overexpression of the multidrug efflux pump smedef impairs stenotrophomonas maltophilia physiology. | the use of antibiotics for the treatment of infectious diseases has led to important changes in the structure of pathogenic bacterial populations. however, these changes could be buffered if the expression of antibiotic resistance genes were to lead to the counter-selection of antibiotic-resistant strains in antibiotic-free environments. to test the effect of antibiotic resistance on bacterial fitness, we analysed the effect of the overproduction of the multidrug efflux pump smedef on the physio ... | 2004 | 14739147 |
| class 1 integrons increase trimethoprim-sulfamethoxazole mics against epidemiologically unrelated stenotrophomonas maltophilia isolates. | twenty-five plasmid-specified antimicrobial resistance determinants common to gram-negative bacilli from nosocomial infection were investigated from 31 stenotrophomonas maltophilia isolates. twenty-four clones were identified by pulsed-field gel electrophoresis, and in three clones that exhibited an increased trimethoprim-sulfamethoxazole mic, the sul1 determinant was found. these results support not only the higher spread of class 1 integrons compared to other mechanisms but also the potential ... | 2004 | 14742234 |
| contribution of integrons, and smeabc and smedef efflux pumps to multidrug resistance in clinical isolates of stenotrophomonas maltophilia. | the contribution of integrons and efflux pumps to multidrug resistance in stenotrophomonas maltophilia was evaluated. | 2004 | 14749340 |
| biodegradation of dna and nucleotides to nucleosides and free bases. | thirty-two different microorganisms were examined in order to check their ability to degrade an exogenous dna. bacteria from species: stenotrophomonas maltophilia, brevundimonas diminuta, bacillus subtilis, mycobacterium butyricum and fungus fusarium moniliforme were capable to degrade dna to nucleic bases or their derivatives. degradation of dna by s. maltophilia resulted in formation of free bases, such as hypoxanthine, thymine, uracil and xanthine. the optimum concentration of dna seemed to b ... | 2004 | 14751311 |
| sphingosine-1-phosphate induces proliferation and morphological changes of neural progenitor cells. | sphingosine-1-phosphate (s1p) is a lipid mediator that exerts multiple cellular functions through activation of g-protein-coupled receptors. although the role of s1p on angiogenesis is well established, its role in neurogenesis is unknown. we examined the effects of s1p on g-protein activation in brain sections of rat embryo and on neural progenitor cells in culture. intense s1p-stimulated [35s]gtpgammas labeling was observed as early as e15 in the neuroepithelium and differentiating fields thro ... | 2004 | 14756825 |
| synthesis, and antiprotozoal and antibacterial activities of s-substituted 4,6-dibromo- and 4,6-dichloro-2-mercaptobenzimidazoles. | the synthesis and some germicidal activities in vitro of two congener series of s-substituted 4,6-dihalogeno-2-mercapto-1h-benzimidazoles are reported. there was no substantial difference between antibacterial activities of corresponding 4,6-dichloro- and 4,6-dibromo-derivatives. the present results confirm lower susceptibility to substituted benzimidazoles of gram-negative compared to gram-positive bacteria. minimum inhibitory concentrations (mics) of a majority of the novel derivatives ranged ... | 2004 | 14757505 |
| high genetic diversity among stenotrophomonas maltophilia strains despite their originating at a single hospital. | the levels of genetic relatedness of 139 stenotrophomonas maltophilia strains recovered from 105 hospitalized non-cystic fibrosis patients (51% from medical wards, 35% from intensive care units, and 14% from surgical wards) and 7 environmental sources in the same hospital setting during a 4-year period were typed by the pulsed-field gel electrophoresis (pfge) technique. a total of 99 well-defined distinct xbai pfge patterns were identified (simpson's discrimination index, 0.996). the dendrogram ... | 2004 | 14766838 |
| microbial transformation of pyrethroid insecticides in aqueous and sediment phases. | recent studies showed that synthetic pyrethroids (sps) can move via surface runoff into aquatic systems. fifty-six of sp-degrading bacteria strains were isolated from contaminated sediments, of which six were evaluated for their ability to transform bifenthrin and permethrin in the aqueous phase and bifenthrin in the sediment phase. in the aqueous phase, bifenthrin was rapidly degraded by strains of stenotrophomonas acidaminiphila, and the half-life (t1/2) was reduced from >700 h to 30 to 131 h. ... | 2004 | 14768859 |
| [corneal infiltrates and ulcers. a retrospective study of 239 eyes]. | in our outpatient service the number of corneal infiltrates and ulcers associated with contact lens wear in young patients increased during the last years. therefore we evaluated all patients with keratitis regarding to the reason. | 2004 | 14872265 |
| in vitro susceptibility of stenotrophomonas maltophilia isolates: comparison of disc diffusion, etest and agar dilution methods. | the disc diffusion, etest and agar dilution techniques were compared to evaluate the antimicrobial susceptibility profile of 70 stenotrophomonas maltophilia isolates to seven antimicrobial agents. the s. maltophilia isolates were consecutively collected from may 2000 to may 2002 from individual patients, who were hospitalized in a private brazilian hospital. the antimicrobial susceptibility tests were carried out and interpreted according to the national committee for clinical laboratory standar ... | 2004 | 14973153 |
| microbiology of early cf lung disease. | recent bronchoscopy studies using assays to measure inflammation and molecular typing techniques have facilitated an increased understanding of the early events that occur within the lungs of young children with cystic fibrosis and provided additional insights into the natural history of lung disease in children. in 2000, the us cf national patient registry data showed that among 1000 infants <2 years of age, the first bacterial pathogens detected are haemophilus influenzae, staphylococcus aureu ... | 2004 | 14980298 |
| [surveillance on antibiotic resistance of stenotrophomonas maltophilia in chengdu and chongqing area]. | to survey the antibiotic resistance of stenotrophomonas maltophilia in chengdu and chongqing area and guide the rational antibiotics usage in the treatment of stenotrophomonas maltophilia infection. | 2004 | 14981826 |
| quantitative evaluation of the therapeutic effects of antibiotics using silkworms infected with human pathogenic microorganisms. | the injection of bacteria (staphylococcus aureus, stenotrophomonas maltophilia) or true fungi (candida albicans, candida tropicalis) that are pathogenic to humans into the silkworm hemolymph leads to death of the larvae within 2 days. antibiotics used for clinical purposes have therapeutic effects on silkworms infected with these pathogens. the 50% effective doses obtained by injection into the silkworm hemolymph are consistent with those reported for mice. injection of vancomycin and kanamycin ... | 2004 | 14982763 |
| activities of ciprofloxacin and moxifloxacin against stenotrophomonas maltophilia and emergence of resistant mutants in an in vitro pharmacokinetic-pharmacodynamic model. | a two-compartment in vitro pharmacokinetic-pharmacodynamic model, with full computer-controlled devices, was used to accurately simulate human plasma pharmacokinetic profiles after multidose oral regimens of ciprofloxacin (750 mg every 12 h) and moxifloxacin (400 mg every 24 h) during 48 h. pharmacodynamics of these drugs was investigated against three quinolone-susceptible strains of stenotrophomonas maltophilia (mics of ciprofloxacin and moxifloxacin of 0.5 to 2 and 0.0625 to 0.5 microg/ml, re ... | 2004 | 14982788 |
| the combination of aztreonam and cefozopran against stenotrophomonas maltophilia. | aztreonam is suited for combination chemotherapy because it could be a potent beta-lactamase inhibitor. we designed a study to show the inhibitory activity of aztreonam, using stenotrophomonas maltophilia, which produces both carbapenemase l1 and penicillinase l2. aztreonam showed considerable synergy with cefpirome and contributed to a decrease in minimum inhibitory concentrations of cefozopran. in further examinations, the mean viable bacterial counts in cultures treated with aztreonam-cefozop ... | 2004 | 14991523 |
| high antibiotic susceptibility among bacterial pathogens in swedish icus. report from a nation-wide surveillance program using ta90 as a novel index of susceptibility. | local infection control measures, antibiotic consumption and patient demographics from 1999-2000 together with bacteriological analyses were investigated in 29 icus participating in the icu-strama programme. the median antibiotic consumption per icu was 1147 (range 605-2143) daily doses per 1000 occupied bed d (ddd1000). antibiotics to which > 90% of isolates of an organism were susceptible were defined as treatment alternatives (ta90). the mean number of ta90 was low (1-2 per organism) for ente ... | 2004 | 15000555 |
| metal binding asp-120 in metallo-beta-lactamase l1 from stenotrophomonas maltophilia plays a crucial role in catalysis. | metallo-beta-lactamase l1 from stenotrophomonas maltophilia is a dinuclear zn(ii) enzyme that contains a metal-binding aspartic acid in a position to potentially play an important role in catalysis. the presence of this metal-binding aspartic acid appears to be common to most dinuclear, metal-containing, hydrolytic enzymes; particularly those with a beta-lactamase fold. in an effort to probe the catalytic and metal-binding role of asp-120 in l1, three site-directed mutants (d120c, d120n, and d12 ... | 2004 | 14573595 |
| bulgecin a: a novel inhibitor of binuclear metallo-beta-lactamases. | bulgecin a, a sulphonated n-acetyl-d-glucosamine unit linked to a 4-hydroxy-5-hydroxymethylproline ring by a beta-glycosidic linkage, is a novel type of inhibitor for binuclear metallo-beta-lactamases. using steady-state kinetic analysis with nitrocefin as the beta-lactam substrate, bulgecin a competitively inhibited the metallo-beta-lactamase bceii from bacillus cereus in its two-zinc form, but failed to inhibit when the enzyme was in the single-zinc form. the competitive inhibition was restore ... | 2005 | 15569001 |
| isolation and characterization of novel giant stenotrophomonas maltophilia phage phisma5. | stenotrophomonas maltophilia is one of the most prevalent opportunistic bacteria causing nosocomial infections. it has become problematic because most of the isolates are resistant to multiple antibiotics, and therefore, development of phage therapy has attracted strong attention. in this study, eight s. maltophilia phages were isolated from clinical samples including patient specimens, catheter-related devices, and wastewater. these phages can be divided into four distinct groups based on host ... | 2005 | 15746341 |
| prospective evaluation of emerging bacteria in cystic fibrosis. | bacteria contribute considerably to the progression of lung disease in cystic fibrosis. in this prospective, multi-centre study, we aimed to evaluate the occurrence of emerging bacteria and the physicians' assessments of the clinical importance of these findings. | 2005 | 15752680 |
| stenotrophomonas maltophilia keratitis after penetrating keratoplasty. | 2005 | 15761487 | |
| changing bacterial isolates and antibiotic sensitivities of purulent dacryocystitis. | to examine the current spectrum of bacterial isolates in cases of chronic dacryocystitis and dacryoabcess and to determine their antibiotic sensitivities. | 2005 | 15764113 |
| nonfermentative gram-negative bacilli in cancer patients: increasing frequency of infection and antimicrobial susceptibility of clinical isolates to fluoroquinolones. | despite a decline in the frequency of gram-negative infections in cancer patients, there has been an increase in the proportion of such infections caused by nonfermentative gram-negative bacilli (nfgnb). we tested the in vitro activity of several quinolones against nfgnb isolated from cancer patients between february 2000 and february 2003, using a broth microdilution method. ciprofloxacin was the most potent agent tested against pseudomonas aeruginosa, although only 80% of isolates were suscept ... | 2005 | 15766609 |
| in vitro activity of levofloxacin against recent gram-negative nosocomial pathogens. | the objective of our study was to evaluate the in vitro activity of levofloxacin in comparison with other antibiotics (coamoxiclav, ceftriaxone, ceftazidime, meropenem, aztreonam, ciprofloxacin and netilmicin) against about 500 gram-negative nosocomial microorganisms, isolated during 2003. the bactericidal activities (minimal bactericidal activity and killing curve) of levofloxacin and the other antibiotics were also evaluated. the results confirm the excellent in vitro activity of levofloxacin ... | 2005 | 15767745 |
| pdgf alpha-receptor signal strength controls an rtk rheostat that integrates phosphoinositol 3'-kinase and phospholipase cgamma pathways during oligodendrocyte maturation. | receptors with tyrosine kinase activity (rtks) control tissue growth and development in metazoans. how they generate cell-specific responses remains essentially unknown; one model proposes that distinct rtks activate different second-messenger pathways, whereas a second proposes that all rtks deliver a generic "go" signal to these pathways that is uniquely interpreted by downstream, cell-specific response competence factors. we examine pathway activation and pathway-specific responses downstream ... | 2005 | 15814780 |
| comparison of in vitro susceptibilities to levofloxacin and ciprofloxacin with pseudomonas aeruginosa and stenotrophomonas maltophilia isolated from cystic fibrosis patients in northern ireland. | 2005 | 15816210 | |
| plant-microbe interactions: identification of epiphytic bacteria and their ability to alter leaf surface permeability. | bacteria were either isolated from leaf surfaces of hedera helix or obtained from a culture collection in order to analyse their effect on barrier properties of isolated hedera and prunus laurocerasus cuticles. on the basis of the 16s rdna sequences the genera of the six bacterial isolates from hedera were identified as pseudomonas sp., stenotrophomonas sp. and achromobacter. water permeability of cuticles isolated from h. helix was measured before and after inoculation with the six bacterial st ... | 2005 | 15819920 |
| phosphate removal from the returned liquor of municipal wastewater treatment plant using iron-reducing bacteria. | the application of iron-reducing bacteria (irb) to phosphate removal from returned liquor (liquid fraction after activated sludge digestion and anaerobic sludge dewatering) of municipal wastewater treatment plant (wwtp) was studied. | 2005 | 15836485 |
| intraspecific differences in bacterial responses to modelled reduced gravity. | bacteria are important residents of water systems, including those of space stations which feature specific environmental conditions, such as lowered effects of gravity. the purpose of this study was to compare responses with modelled reduced gravity of space station, water system bacterial isolates with other isolates of the same species. | 2005 | 15836494 |
| trimethoprim-sulfamethoxazole in the treatment of stenotrophomonas maltophilia osteomyelitis. | 2005 | 15844086 | |
| rapid detection and identification of pathogens in blood cultures by fluorescence in situ hybridization and flow cytometry. | septicemia is one of the leading causes of death in hospitalized patients. the timely detection and identification of microorganisms from the patient's blood has great diagnostic, prognostic and economic significance. fluorescence in situ hybridization (fish) with rrna-targeted oligonucleotide probes has been proven to be a fast method for the identification of human pathogenic bacteria and yeasts. data presented herein reveal that the combination of fish and flow cytometry (fc-fish) is a rapid ... | 2005 | 15861816 |
| significance of positive stenotrophomonas maltophilia culture in acute respiratory tract infection. | stenotrophomonas maltophilia is a common coloniser of the respiratory tract of patients with chronic lung disease, and, in the absence of pneumonia or bacteraemia, is often ignored by physicians at the royal perth hospital (perth, australia). experience at the royal perth hospital was reviewed to determine whether ignoring s. maltophilia in this setting has any apparent effect on clinical outcome. all patients who presented with an acute respiratory illness and yielded a positive culture for s. ... | 2005 | 15863651 |
| isolation of infectious cystic fibrosis patients: results of a systematic review. | respiratory tract infections significantly contribute to morbidity and mortality among cystic fibrosis (cf) patients. therefore, pathogen transmission needs to be prevented. there are several guidelines for the care of cf patients, but no transparent systematic literature review has been published. | 2005 | 15865277 |
| gram-negative bacteria from the camel tick hyalomma dromedarii (ixodidae) and the chicken tick argas persicus (argasidae) and their antibiotic sensitivities. | a total of nine species of gram-negative bacteria were isolated from organs and haemolymph of the hard tick hyalomma (hyalomma) dromedarii and the soft tick argas (persicargas) persicus. four species namely serratia liquefaciens, stenotrophomonas maltophilia, klebsiella ornithinolytica and aeromonas hydrophila were isolated from h. dromedarii and five species namely rahnella aquatilis, pseudomonas fluorescens, enterobacter cloacae, chryseomonas luteola and chryseobacterium meningosepticum were i ... | 2005 | 15880998 |
| isolation and characterization of diazotrophic growth promoting bacteria from rhizosphere of agricultural crops of korea. | free-living nitrogen fixing bacteria were isolated from rhizosphere of seven different plant namely sesame, maize, wheat, soybean, lettuce, pepper and rice grown in chungbuk province, korea. five isolates with nitrogenase activity above 150nmol(-1) mg(-1) protein were identified based on, phenotypic and 16s rdna sequences analysis. the strains were identified as stenotrophomonas maltophilia (pm-1, pm-26), bacillus fusiformis (pm-5, pm-24) and pseudomonas fluorescens (pm-13), respectively. all th ... | 2005 | 15881829 |
| the antimicrobial susceptibility of stenotrophomonas maltophilia isolates using three different methods and their genetic relatedness. | stenotrophomonas maltophilia is inherently resistant to many antimicrobials. so far, antimicrobial susceptibility tests for s. maltophilia have not been fully standardized. the purpose of the study was to compare the susceptibility of s. maltophilia isolates against seven different antimicrobials using three different methods and to investigate their genetic relatedness. | 2005 | 15882456 |
| [nosocomial stenotrophomonas maltophilia infections in a university hospital]. | stenotrophomonas maltophilia is a nosocomial pathogen of increasing importance. in our study, 190 s. maltophilia strains isolated from 153 hospitalized patients between january 2000-april 2004, at farabi hospital at medical school of karadeniz technical university, were prospectively evaluated. of these patients 67.9% were clinically compatible with nosocomial infection, and 32% were considered as colonization. it was observed that rate of infection had a tendency to increase one year of age and ... | 2005 | 15900834 |
| chromosome-borne class a bor-1 beta-lactamase of bordetella bronchiseptica and bordetella parapertussis. | a narrow-spectrum clavulanic acid-inhibited class a beta-lactamase, bor-1, was identified in a bordetella bronchiseptica clinical isolate. it shared 45% amino acid identity with l-2 from stenotrophomonas maltophilia. an identical beta-lactamase gene was found in b. bronchiseptica and bordetella parapertussis reference strains that may contribute only in part to their resistance phenotype. | 2005 | 15917575 |
| risk factors for allergic bronchopulmonary aspergillosis and sensitisation to aspergillus fumigatus in patients with cystic fibrosis. | an increasing incidence of allergic bronchopulmonary aspergillosis (abpa) as a complication in patients with cystic fibrosis (cf) is reported. the objective of this retrospective case-control study was to assess potential risk factors for abpa and for aspergillus fumigatus sensitisation (afs). in a group of 160 cf patients, 11 (7%) fulfilled the diagnostic criteria for abpa and 20 (13%) had evidence of afs. they were compared to 62 control cf patients (25 for abpa and 37 for afs group) without e ... | 2005 | 15926067 |
| preservation of topoisomerase genetic sequences during in vivo and in vitro development of high-level resistance to ciprofloxacin in isogenic stenotrophomonas maltophilia strains. | to ascertain the participation of topoisomerase mutations in the development of ciprofloxacin resistance in isogenic stenotrophomonas maltophilia mutants. | 2005 | 15928010 |
| bloodstream infection after umbilical cord blood transplantation using reduced-intensity stem cell transplantation for adult patients. | bloodstream infection (bsi) is a significant problem after cord blood transplantation (cbt). however, little information has been reported on bsi after reduced-intensity cbt (ri-cbt). we retrospectively reviewed the medical records of 102 patients. the median age of the patients was 55 years (range, 17-79 years). preparative regimens comprised fludarabine 125 to 150 mg/m 2 , melphalan 80 to 140 mg/m 2 , or busulfan 8 mg/kg and total body irradiation 2 to 8 gy. prophylaxis against graft-versus-ho ... | 2005 | 15931631 |
| a new method for production of valienamine with microbial degradation of acarbose. | a new method for the production of valienamine with the microbial degradation of acarbose is described. the microorganism was screened by our laboratory and identified as stenotrophomonas maltrophilia. after separation, valienamine was analyzed with uv, ir, and 1h and 13c nmr. the yield was more than 60%. | 2005 | 15932287 |
| hospital-acquired pneumonia in critically ill patients: factors associated with episodes due to imipenem-resistant organisms. | inadequate initial antimicrobial therapy represents one of the factors associated with mortality of patients suffering from hospital-acquired pneumonia. according to its wide antimicrobial spectrum, imipenem belongs to the usual antibiotics proposed by current guidelines for such a therapy. however, major changes in the antibiotic susceptibility patterns of bacteria in the intensive care unit (icu) have occurred. our goal was to determine the incidence of hospital-acquired pneumonia (hap) due to ... | 2005 | 15940413 |
| stenotrophomonas maltophilia keratitis and scleritis. | stenotrophomonas maltophilia is a seldom-reported pathogen in ocular infections. the report describes six cases of stenotrophomonas maltophilia (s. maltophilia) keratitis and scleritis. to our knowledge, this is the foremost report of s. maltophilia scleritis. | 2005 | 15945320 |
| a 55-year-old smoker with a persistent right lower lobe infiltrate. | 2005 | 15947347 | |
| rhizosphere-induced selenium precipitation for possible applications in phytoremediation of se polluted effluents. | two bacterial isolates were obtained in axenic culture from the rhizosphere soil of astragalus bisulcatus, a legume able to hyperaccumulate selenium. both strains resulted of particular interest for their high resistance to the toxic oxyanion seo3(2-) (selenite, se(iv)). on the basis of molecular and biochemical analyses, these two isolates were attributed to the species bacillus mycoides and stenotrophomonas maltophilia, respectively. their capability in axenic culture to precipitate the solubl ... | 2005 | 15948605 |
| [study on the molecular epidemiology of stenotrophomonas maltophilia infection in patients on mechanical ventilation]. | to investigate a potential outbreak of stenotrophomonas maltophilia (pma) infection occurred in patients on mechanical ventilation in a respiratory icu (ricu) and to track the infective origins by antibiotype and pulsed-field gel electrophoresis (pfge) typing methods. | 2005 | 15949310 |
| disease risk and mortality prediction in intensive care patients with pneumonia. australian and new zealand practice in intensive care (anzpic ii). | this study of ventilated patients investigated pneumonia risk factors and outcome predictors in 476 episodes of pneumonia (48% community-acquired pneumonia, 24% hospital-acquired pneumonia, 28% ventilator-associated pneumonia) using a prospective survey in 14 intensive care units within australia and new zealand. for community acquired pneumonia, mortality increased with immunosuppression (or 5.32, ci 95% 1.58-1799, p<0.01), clinical signs of consolidation (or 2.43, ci 95% 1.09-5.44, p=0.03) and ... | 2005 | 15957699 |
| profiling bacterial survival through a water treatment process and subsequent distribution system. | to profile fractions of active bacteria and of bacteria culturable with routine heterotrophic plate count (hpc) methods through a typical water treatment process and subsequent distribution system. in doing so, investigate how water treatment affects both bacterial abundance and diversity, and reveal the identities of active bacteria not detected by traditional hpc culture. | 2005 | 15960678 |
| antifolate activity of epigallocatechin gallate against stenotrophomonas maltophilia. | the catechin epigallocatechin gallate, one of the main constituents of green tea, showed strong antibiotic activity against 18 isolates of stenotrophomonas maltophilia (mic range, 4 to 256 microg/ml). in elucidating its mechanism of action, we have shown that epigallocatechin gallate is an efficient inhibitor of s. maltophilia dihydrofolate reductase, a strategic enzyme that is considered an attractive target for the development of antibacterial agents. the inhibition of s. maltophilia dihydrofo ... | 2005 | 15980368 |
| antimicrobial peptide therapeutics for cystic fibrosis. | greater than 90% of lung infections in cystic fibrosis (cf) patients are caused by pseudomonas aeruginosa, and the majority of these patients subsequently die from lung damage. current therapies are either targeted at reducing obstruction, reducing inflammation, or reducing infection. to identify potential therapeutic agents for the cf lung, 150 antimicrobial peptides consisting of three distinct structural classes were screened against mucoid and multidrug-resistant clinical isolates of p. aeru ... | 2005 | 15980369 |
| ['in vitro' activity of different antimicrobial agents on gram-negative nonfermentative bacilli, excluding pseudomonas aeruginosa and acinetobacter spp]. | gram-negative nonfermentative bacilli (nfb) are widely spread in the environment. besides of difficulties for identification, they often have a marked multiresistance to antimicrobial agents, including those active against pseudomonas aeruginosa. the objective of this study was to evaluate the 'in vitro' activity of different antimicrobial agents on 177 gram-negative nonfermentative bacilli isolates (excluding pseudomonas aeruginosa and acinetobacter spp.) isolated from clinical specimens. minim ... | 2005 | 15991478 |
| [epidemiology of nosocomial infections due to pseudomonas aeruginosa, burkholderia cepacia and stenotrophomonas maltophilia]. | non-fermentative gram negative rods are opportunistic pathogens responsible for nosocomial infections. using phenotypic markers (serotypes for pseudomonas aeruginosa and antibiotic susceptibility) allows a preliminary screening of epidemiologically-related strains. however, genotypic markers are necessary to better characterize nosocomial strains for the investigation of outbreaks or cross-transmissions in the hospital setting. infections due to p. aeruginosa, burkholderia. cepacia or stenotroph ... | 2005 | 16004946 |
| characterization of salt-tolerant glutaminase from stenotrophomonas maltophilia nyw-81 and its application in japanese soy sauce fermentation. | glutaminase from stenotrophomonas maltophilia nyw-81 was purified to homogeneity with a final specific activity of 325 u/mg. the molecular mass of the native enzyme was estimated to be 41 kda by gel filtration. a subunit molecular mass of 36 kda was measured with sds-page, thus indicating that the native enzyme is a monomer. the n-terminal amino acid sequence of the enzyme was determined to be keaetqqklanvvilatggtia. besides l: -glutamine, which was hydrolyzed with the highest specific activity ... | 2005 | 16012776 |
| exposure to airborne microorganisms, dust and endotoxin during processing of valerian roots on farms. | the aim of this study was to determine the levels of microorganisms, dust and endotoxin in the air during various stages of valerian (valeriana officinalis) roots processing by herb farmers and to examine the species composition of airborne microflora. air samples were collected on glass fibre filters by use of personal samplers on 15 farms owned by valerian cultivating farmers, located in lublin province (eastern poland). the concentrations of total viable microorganisms (bacteria + fungi) in t ... | 2005 | 16028876 |
| stenotrophomonas maltophilia in salad. | 2005 | 16032800 | |
| in vitro evaluation of efficacy of 5 methods of disinfection on mouthpieces and facemasks contaminated by strains of cystic fibrosis patients. | home-nebulizers are a potential source of bacterial infection of the respiratory tract in patients suffering from cystic fibrosis. recommendations for disinfecting this equipment are often arbitrary and sometimes contradictory. | 2005 | 16046195 |
| [in vitro activity of commercially available disinfectants against stenotrophomonas maltophilia]. | in vitro antibacterial efficacy of 14 commercially available disinfectants against the hospital pathogen stenotrophomonas maltophilia was tested. the test disinfectants included 5 "pure" quartenary ammonium compounds (qacs) and 9 combination formulations with qacs as the major ingredient. antibacterial efficacy was expressed as mic, ed50 and inhibition of the rate of incorporation of radioactive precursors [14c] adenine and [14c] leucine. based on their activity, the disinfectants were divided i ... | 2005 | 16050547 |
| [use of 16s rrna gene sequencing for identification of "pseudomonas-like" isolates from sputum of patients with cystic fibrosis]. | since nonfermenting, gram negative bacilli recovered from patients with cystic fibrosis could be misidentified with phenotypic procedures, we used partial 16s ribosomal rna gene (16s gene) sequencing to identify these "pseudomonas-like" isolates. 473 isolates were recovered from 66 patients in 2003. sequencing was used to identify 29 (from 24 patients) of the 473 isolates, showing unclear results with routine tests. pcr with specific primers was carried out to amplify a 995 bp fragment, which wa ... | 2005 | 16081224 |
| life-threatening chronic enteritis due to colonization of the small bowel with stenotrophomonas maltophilia. | chronic diarrheal illness and malabsorption are challenging diagnostic and clinical problems. the identification of the causative pathogens that are involved in gastrointestinal infections is often difficult. it took 85 years after the first description of a case of intestinal lipodystrophy by georg whipple in 1907 until the causative bacterium was characterized by using molecular genetics techniques. we here report the complicated clinical course of a young patient with chronic diarrhea accompa ... | 2005 | 16083723 |
| silanimonas lenta gen. nov., sp. nov., a slightly thermophilic and alkaliphilic gammaproteobacterium isolated from a hot spring. | a moderately thermophilic aerobic bacterium, strain 25-4t, was isolated from a hot spring at baekdoo mountain in korea. the cells were gram-negative, motile rods each having a polar flagellum. analysis of the 16s rrna gene sequence indicated that the strain represented a new lineage within the family 'xanthomonadaceae' of the 'gammaproteobacteria', being most closely related to the genera thermomonas, xanthomonas, luteimonas, pseudoxanthomonas, stenotrophomonas and xylella and having 16s rrna ge ... | 2005 | 15653905 |
| direct evidence that the reaction intermediate of metallo-beta-lactamase l1 is metal bound. | in an effort to probe the structure of the reaction intermediate of metallo-beta-lactamase l1 when reacted with nitrocefin and other beta-lactams, time-dependent absorption and rapid-freeze-quench (rfq) epr spectra were obtained using the co(ii)-substituted form of the enzyme. when using nitrocefin as the substrate, time-dependent absorption spectra demonstrate that co(ii)-substituted l1 utilizes a reaction mechanism, similar to that of the native zn(ii) enzyme, in which a short-lived intermedia ... | 2005 | 15654764 |
| a specific peptide inhibitor of the class b metallo-beta-lactamase l-1 from stenotrophomonas maltophilia identified using phage display. | in gram-negative bacteria, resistance to beta-lactam antibiotics and to known inhibitors mediated by metallo-beta-lactamases is a major concern and a serious threat to public health. since no clinically useful inhibitors are available against class b metallo-beta-lactamases, the aim of the study was to identify peptides as inhibitors. | 2005 | 15659541 |
| selenite precipitation by a rhizospheric strain of stenotrophomonas sp. isolated from the root system of astragalus bisulcatus: a biotechnological perspective. | a bacterial strain (seite02), related to the species stenotrophomonas maltophilia and resistant to selenite (seiv) up to 50 mm in the growth medium, was isolated from rhizospheric soil of a selenium hyperaccumulator plant, the legume astragalus bisulcatus. the influence of seiv on the active growth of this se-tolerant bacterial strain has been investigated in oxic conditions, along with the isolate's ability to reduce selenite to elemental selenium (se(0)). interestingly, concentrations of 0.5 m ... | 2005 | 15661289 |
| antimicrobial susceptibility of uncommonly isolated non-enteric gram-negative bacilli. | the frequency of occurrence and antimicrobial susceptibility patterns of 3059 non-enteric gram-negative bacilli (ngb), other than pseudomonas aeruginosa and acinetobacter spp., consecutively collected as part of the sentry antimicrobial surveillance program (1997-2003) were reviewed. during this period, a total of 221,084 bacterial isolates were collected from several clinical specimens worldwide, including 25,305 (11.5%) ngb. acinetobacter spp. and p. aeruginosa accounted for 82.7% of the ngb i ... | 2005 | 15664479 |
| synthesis of the compatible solutes glucosylglycerol and trehalose by salt-stressed cells of stenotrophomonas strains. | in this study, physiological processes were analysed, which are involved in salt acclimation of two stenotrophomonas species, stenotrophomonas maltophilia strain dsm 50170 and stenotrophomonas rhizophila strain dsm 14405. s. maltophilia accumulated trehalose as the only osmolyte, whereas s. rhizophila produced additionally to trehalose glucosylglycerol (gg). the different spectrum and amounts of compatible solutes in these two strains led to differences in terms of their salt tolerance. the huma ... | 2005 | 15668022 |
| superinfection of perinephric abscess by stenotrophomonas maltophilia in a tetraplegic patient. | 2005 | 15672091 | |
| the biocide triclosan selects stenotrophomonas maltophilia mutants that overproduce the smedef multidrug efflux pump. | the possibility that triclosan selects stenotrophomonas maltophilia mutants overexpressing the multidrug resistance pump smedef is analyzed. five out of 12 triclosan-selected mutants were less susceptible to antibiotics than the wild-type strain and overproduced smedef. results are discussed in relation to current debates on the potential selection of antibiotic-resistant bacteria by household biocides. | 2005 | 15673767 |
| effect from multiple episodes of inadequate empiric antibiotic therapy for ventilator-associated pneumonia on morbidity and mortality among critically ill trauma patients. | empiric antibiotic therapy is routinely initiated for patients with presumed ventilator-associated pneumonia (vap). the impact of inadequate empiric antibiotic therapy (ieat) may vary among critically ill populations. the purpose of this retrospective study was to determine the effect of ieat on the outcome for adult trauma patients with vap. | 2005 | 15674157 |