Publications

a case of polymicrobial endocarditis caused by anaerobic organisms in an injection drug user.	endocarditis is a serious complication of injection drug use most commonly caused by staphylococcus aureus. we report a case of tricuspid valve polymicrobial bacterial endocarditis in an injection drug user from 3 oral anaerobes: actinomyces odontolytica, veillonella species, and prevotella melaninogenica. the patient was believed to have acquired these organisms from his habit of licking the needle in order to gauge the strength of the cocaine prior to injection. the patient was successfully tr ...	2005	16191149
serum antibodies to oral anaerobic bacteria in patients with rheumatoid arthritis.	this study was conducted to determine the component that causes the disease in rheumatoid arthritis (ra), which shows great resemblance to periodontitis in a pathologic context.	2005	16369381
bacteriological study of paediatric and adult chronic suppurative otitis media.	chronic suppurative otitis media (csom) is one of the commonest illnesses in ent practice which requires medical attention all the more in children of poor socio-economic status having in past inadequate treatment and negligent medical care. the present study was conducted to find out the various aerobic and anaerobic microorganisms associated with csom in paediatric and adult cases and their current antimicrobial susceptibility pattern as a guide to therapy. samples were collected from 109 clin ...	2005	16761774
properties of hemagglutination by prevotella melaninogenica.	although prevotella melaninogenica belongs to the commensal oral microbiota, some strains possess putative virulence factors. for example, we have previously described fimbriated, hemagglutinating strains of p. melaninogenica, isolated from patients with periodontal disease. the aim of this investigation was to compare some chemical and physical properties of hemagglutination (ha) of p. melaninogenica with those of other pigmented gram-negative anaerobes. ha of 13 p. melaninogenica strains prove ...	2005	16701585
microbiota of the dorsum of the tongue after plaque accumulation: an experimental study in humans.	the purpose of the present investigation was to determine the effect of the absence of tongue hygiene on the microbiota of the dorsum of the tongue.	2006	16945032
aetiology of caprine footrot in extremadura region, spain.	the present study reports on the location of major foci of footrot in goats in the extremadura region of spain by the determination of locally occurring strictly anaerobic microorganisms involved in the pathogenesis and development of this disease. the most commonly isolated microorganisms belonged to the genera dichelobacter, fusobacterium, porphyromonas and prevotella; these were found in conjunction with other species of minor importance. the species most frequently isolated were fusobacteriu ...	2006	17020135
bacterial diversity in aortic aneurysms determined by 16s ribosomal rna gene analysis.	aortic aneurysms are common vascular conditions that cause considerable morbidity and mortality. understanding of the mechanisms involved in the pathogenesis of the condition remains limited. recently, infection has been suggested as possible contributor in the development of the disease. the aim of the present study was to examine aortic aneurysms for the presence of bacterial dna using polymerase chain reaction (pcr) targeting the 16s ribosomal rna (rrna) gene, followed by cloning and sequenci ...	2006	17098542
vaginal mesh infection due to bacteroides melaninogenicus: a case report of another emerging foreign body related infection.	we present a case of a 29-y-old woman with rectocele, cystocele, and uterine prolapse who developed a vaginal infection after the placement of a macroporous polypropylene vaginal mesh. bacteroides melaninogenicus was isolated from the area of the infection. the exposed parts of the mesh were removed and she received treatment with metronidazole and doxycycline. no recurrence of the infection was noted during 12 months of follow-up. however, the patient continued to avoid intercourse due to sever ...	2006	17148089
the microbiological origin of fluorescence observed in plaque on dentures during qlf analysis.	the aim of this study was to determine the microbiological origin of plaque fluorescence observed during quantitative light-induced fluorescence (qlf) analysis. plaque was sampled from dentures, because of easy accessibility and the homogeneous background provided by the denture tooth during imaging, and the acknowledged comparability to occlusal plaque. forty removable poly(methyl methacrylate) dentures were screened for the presence of fluorescent plaque deposits during qlf analysis. dentures ...	2006	16508267
proteinase activity of prevotella species associated with oral purulent infection.	prevotella intermedia and prevotella nigrescens are often regarded as principal causes of acute dentoalveolar infection; however, other species within the genus are also known to be associated with such infection. the aim of this study was to determine the in vitro proteolytic activity of these different prevotella species that have been implicated with dentoalveolar infection. a total of 234 strains were obtained from pus specimens from dentoalveolar infection and from the plaque of healthy vol ...	2006	16586023
black stains in the mixed dentition: a pcr microbiological study of the etiopathogenic bacteria.	the aim of this work is to emphasize that particular stains on the third cervical of the buccal and lingual surfaces in mixed dentition, called "black stain." previous research showed the microbiological etiology of this discoloration by chromogen bacterias. our study shows bacteria spp involved in stains by means of pcr process and electrophoresis gel on the agarose medium. sample was formed by 100 subject with black stain and 100 control subjects stain-free. a statistical analysis (spss 10.0) ...	2006	16683670
human serum activity of telithromycin, azithromycin and amoxicillin/clavulanate against common aerobic and anaerobic respiratory pathogens.	telithromycin is a new ketolide antimicrobial with a good in vitro activity against both aerobic and anaerobic respiratory pathogens. in this study, we evaluated the antibacterial activity over time of telithromycin (800mg), azithromycin (500mg), and amoxicillin/clavulanate (875/125mg) in serum following single oral doses of these agents to 10 healthy subjects. inhibitory and bactericidal titers were determined at 2, 6, 12, and 24h after each dose and the median titer was used to determine antib ...	2007	17189093
activities of four frog skin-derived antimicrobial peptides (temporin-1dra, temporin-1va and the melittin-related peptides ar-23 and rv-23) against anaerobic bacteria.	the activities of two antimicrobial peptides belonging to the temporin family (temporin-1dra from rana draytonii and temporin-1va from rana virgatipes) and two peptides with structural similarity to the bee venom peptide melittin (ar-23 from rana tagoi and rv-23 from r. draytonii) were evaluated against a range of reference strains and clinical isolates of anaerobic bacteria. these peptides were selected because they show broad-spectrum growth inhibitory activity against reference strains of sev ...	2007	17196372
effect of 308-nm excimer laser light on peri-implantitis-associated bacteria: an in vitro investigation.	dental implants are becoming increasingly important in prosthodontic rehabilitation. bacterial infections, however, can induce bone loss and jeopardize clinical success. recent literature has demonstrated that infrared co(2) laser light is suitable for the decontamination of exposed implant surfaces. the aim of the present study was to investigate the influence of 308-nm excimer laser irradiation on peri-implantitis-associated bacteria in vitro. in this study, a xecl excimer laser (308 nm) was u ...	2007	17318664
in vitro antimicrobial activity of propolis samples from different geographical origins against certain oral pathogens.	propolis is an agent having antimicrobial properties, however, its composition can vary depending on the area where it is collected. in the present study, the antimicrobial activity of five propolis samples, collected from four different regions in turkey and from brazil, against nine anaerobic strains was evaluated. ethanol extracts of propolis (eep) were prepared from propolis samples and we determined minimum inhibitory concentrations (mic) and minimum bactericidal concentrations (mbc) of eep ...	2007	17475517
an ex-situ arterial reconstruction for the treatment of an infected suprarenal abdominal aortic aneurysm involving visceral vessels.	a 66-year-old man, who had complaints of back pain, high fever, and constipation, with a suprarenal infected abdominal aortic aneurysm involving visceral vessels, was successfully treated by an ex situ arterial reconstruction. blood culture revealed bacteroides melaninogenicus. after establishing a temporary bypass from right axillary to right external iliac artery, both renal arteries--superior mesenteric artery and common hepatic artery--were preliminary bypassed from external iliac arteries. ...	2007	17484976
odontogenic bacteria in periodontal disease and resistance patterns to common antibiotics used as treatment and prophylaxis in odontology in spain.	resistance in streptococci or gram-negative bacteria is associated with antibiotic consumption. scarce information exists on the antibiotic susceptibility of bacterial isolates from patients with periodontitis in countries with high antibiotic consumption, as this is an area in which microbiological testing is not performed in daily practice. the present study was undertaken to explore the susceptibility of bacterial isolates in periodontitis to antibiotics prescribed in odontology in spain as t ...	2007	17530037
[composition of microflora and antibiotic sensitivity of bacteria of the women urogenital tract].	a microbial landscape of the urogenital tract in 798 women of reproductive age with various inflammatory diseases of urogenital organs has been investigated. it was fixed, that in 57% of cases the microflora of genitalias of the examined women was presented by associations of aerobic and anaerobic agents. the following associations were distinguished: staphylococci-bacteroides fragilis (34%), enterobacteria-bacteroides melaninogenicus (24%), enterobacteria-anaerobe cocci (15%), staphylococci-b. ...	2007	17682531
prevotella paludivivens sp. nov., a novel strictly anaerobic, gram-negative, hemicellulose-decomposing bacterium isolated from plant residue and rice roots in irrigated rice-field soil.	two strictly anaerobic bacterial strains, kb7(t) and a42, were isolated from rice plant residue and living rice roots, respectively, from irrigated rice-field soil in japan. these two strains were closely related to each other with 16s rrna gene sequence similarity of 99.8 %. both strains showed almost the same physiological properties. cells were gram-negative, non-motile, non-spore-forming rods. growth was remarkably stimulated by the addition of haemin to the medium. the strains utilized vari ...	2007	17684261
evaluation of the microbiota of primary endodontic infections using checkerboard dna-dna hybridization.	the aim of this study was to evaluate the composition of the microbiota of primary endodontic infections in 111 selected cases of single-rooted teeth with necrotic pulp.	2007	17949342
rapid identification of non-sporing anaerobes using nuclear magnetic resonance spectroscopy and an identification strategy.	the non-sporing anaerobes cause a wide spectrum of infections. they are difficult to culture and their identification is tedious and time-consuming. rapid identification of anaerobes is highly desirable. towards this end, the potential of nuclear magnetic resonance (nmr) spectroscopy for providing a fingerprint within the proton spectrum of six genera belonging to anaerobes reflecting their characteristic metabolites has been investigated.	2007	18087080
orbital abscess secondary to acute dacryocystitis: case report.	acute dacryocystitis usually induces preseptal infection. in rare instances the infection that is confined to the lacrimal sac can extend to the orbital contents resulting in orbital cellulitis. we present a case of intraconal abscess secondary to acute dacryocystitis and review the literature of orbital cellulitis resulting from acute lacrimal sac infection.	2008	18797671
bacteriological and clinical evaluation of twelve cases of post-surgical sepsis of odontogenic tumours at a referral centre.	to determine the bacterial aetiology of sepsis occurring following surgery of odontogenic tumours and assess the effect of prompt and proper antibiotic usage.	2008	18817023
headache of a diagnosis: frontotemporal pain and inflammation associated with osteolysis.	a 62-year-old woman presented with left frontotemporal pain, scalp tenderness and raised levels of inflammatory markers. temporal arteritis was considered likely, and symptoms resolved with prednisone therapy. this delayed diagnostic bone biopsy until a soft tissue abscess formed, and pott's puffy tumour associated with prevotella osteomyelitis of the frontal bone was diagnosed. this case highlights the value of early histopathological examination, and is a reminder of a condition seen frequentl ...	2008	19012561
[preparation and antibacterial activity of quaternary ammonium salt monomers].	to prepare three quaternary ammonium salt (qas) monomers, and to compare their antibacterial activities against four oral bacterial strains.	2008	19031791
molecular identification of bacteria on the tongue dorsum of subjects with and without halitosis.	compare the microbial profiles on the tongue dorsum in patients with halitosis and control subjects in a uk population using culture-independent techniques.	2008	18336372
oxygen induces mutation in a strict anaerobe, prevotella melaninogenica.	strict anaerobes are highly sensitive to oxygen, but the mutagenicity of oxygen in strict anaerobes has not been well understood. prevotella melaninogenica, a strict anaerobe, is susceptible to oxygen and shows an increase in oxidative dna damage upon exposure to oxygen. in this study, we have investigated the mutagenicity of oxygen and the types of mutations induced by oxygen. exposure to oxygen decreased cell survival and increased the levels of 8-oxo-deoxyguanosine (8-oxodg). the frequency of ...	2008	18343236
comparison of the copan eswab system with two amies agar swab transport systems for maintenance of microorganism viability.	swab transport systems are used for a variety of specimen types and must maintain organism viability throughout the transport process. the copan eswab is a new nylon-flocked swab designed to optimize specimen collection and to minimize entrapment of the specimen. we used the quantitative elution method with recommended strains, as described in clsi document m40-a, to evaluate the eswab for maintenance of viability of aerobic and anaerobic microorganisms for 0, 6, 24, and 48 h during room tempera ...	2008	18353935
the lower genital tract microbiota in relation to cytokine-, slpi- and endotoxin levels: application of checkerboard dna-dna hybridization (cdh).	in the present study the lower genital tract microbiota in asymptomatic fertile women (n=34) was identified and quantified by culturing vaginal secretions. also, vaginal and cervical samples were analyzed by a semiquantitative checkerboard dna-dna hybridization technique (cdh) based on genomic probes prepared from 13 bacterial species (bacteroides ureolyticus, escherichia coli, fusobacterium nucleatum, gardnerella vaginalis, mobiluncus curtisii ss curtisii, prevotella bivia, prevotella disiens, ...	2008	18397461
mycobacterium fortuitum and anaerobic breast abscess following nipple piercing: case presentation and review of the literature.	body piercing has become increasingly prevalent. we describe a case of breast infection with combined mycobacteria and anaerobe following nipple piercing, and review the literature.	2008	18407050
the relationship of prevotella intermedia, prevotella nigrescens and prevotella melaninogenica in the supragingival plaque of children, caries and oral malodor.	a relationship between the distribution of periodontal bacteria species and malodor in children has not been sufficiently investigated. the present study was undertaken to determine the presence of 3 periodontopathic bacteria (prevotella spp. p. intermedia, p. nigrescens, p. melaninogenica) in the supragingival plaques of 3 to 16-year-old children with different oral health conditions and oral malodor.	2008	18524268
pcr-based identification of selected pathogens associated with endodontic infections in deciduous and permanent teeth.	the aim of the present study was to evaluate the presence of the selected pathogens in samples from deciduous and permanent tooth root canals by using pcr method and to determine the association of these organisms with clinical symptoms.	2008	18547832
an evaluation of bacterial contamination of barriers used in periapical tissue regeneration: part 1--bacterial adherence.	to compare the adherence of prevotella melaninogenica and enterococcus faecalis to 3 guided tissue regeneration membranes: atrisorb, lambone, and osseoquest. it was hypothesized that osseoquest would show increased bacterial adherence compared to lambone and atrisorb.	2008	18560654
periodontal status of patients with dentin dysplasia type i: report of three cases within a family.	dentin dysplasia type i (ddi) is a rare hereditary disturbance of dentin formation. it is characterized by clinically normal-appearing crowns; obliteration of pulp chambers; and short, blunted and malformed roots that are commonly associated with periodontal attachment loss (pal). in this context, we report three cases within a family with similar clinical and radiographic features of ddi but with differing microbiologic and periodontal conditions.	2008	18597615
an evaluation of bacterial contamination of barriers used in periapical tissue regeneration: part 2--bacterial penetration.	to compare the relative penetration of prevotella melaninogenica and enterococcus faecalis through 3 guided tissue regeneration membranes: atrisorb, lambone, and osseoquest. it was hypothesized that osseoquest would show increased bacterial penetration when compared to lambone and atrisorb.	2008	18618039
fluid-containing emphysematous bullae: a spectrum of illness.	fluid-containing emphysematous bullae are an under-reported complication of chronic obstructive pulmonary disease. the roles of bronchoscopy in the work-up and of antibiotics in the treatment are undefined. this study reports the combined results from the analysis of 16 cases treated at the present authors' institution and 36 previously reported cases. the median age at presentation was 58 yrs and the median duration of follow-up was 60 weeks. a third of the patients were asymptomatic, while two ...	2008	18669786
prevotella histicola sp. nov., isolated from the human oral cavity.	three strains of anaerobic, variably pigmenting, gram-negative bacilli isolated from human oral mucosal tissue were subjected to a comprehensive range of phenotypic and genotypic tests and were found to comprise a homogeneous group. 16s rrna gene sequence analysis and dna-dna hybridization revealed that the strains constituted a novel group within the genus prevotella, being most closely related to prevotella melaninogenica and prevotella veroralis. a novel species, prevotella histicola sp. nov. ...	2008	18676457
necessary corrections to the approved lists of bacterial names according to rule 40d (formerly rule 46). opinion 86.	the judicial commission affirms that, according to rule 40d, formerly rule 46, of the bacteriological code, the authorship of a number of subspecies names included on the approved lists of bacterial names must be corrected. these names are acetobacter aceti subsp. aceti, acetobacter pasteurianus subsp. pasteurianus, bacteroides melaninogenicus subsp. melaninogenicus, campylobacter fetus subsp. fetus, mycobacterium chelonae subsp. chelonae, propionibacterium freudenreichii subsp. freudenreichii, ...	2008	18676492
recurrent unilateral periorbital cellulitis in a pediatric patient--an anatomic abnormality.	a 2-year-old male, otherwise healthy, suffered a total of 7 episodes of recurrent right-sided periorbital celluitis (poc) which began at 11 months of age. five of the 7 episodes of right eye swelling/erythema required hospital admission for intravenous antibiotics. imaging studies demonstrated a well-defined dehiscence in the lamina papyracea. endoscopic sinus surgery was performed and an abnormal uncinate process was visualized, fused to the lateral nasal wall and ethmoid bulla. post-operativel ...	2008	18703235
[anaerobic gram-negative bacilli involved in the etiopathogeny of the abscesses of superficial fascial spaces of the face and neck].	the aim of this study was to isolate and identify at species level the strains of anaerobic gram-negative bacilli (gnb) from pus samples collected in patients with abscesses of fascial spaces of the face and neck. microscopy of gram-stained smears and cultures were performed in each specimen. the strictly anaerobic gnb strains were identified using the conventional methods of diagnosis and the rapid id 32 a system. in addition, the other strains isolated in association with these bacteria were i ...	2008	20201270
in vitro bactericidal activity of recombinant human beta-defensin-3 against pathogenic bacterial strains in human tooth root canal.	human beta-defensin-3 (hbd3), an endogenous antimicrobial peptide, has strong broad-spectrum antimicrobial activity. this study aimed to obtain recombinant hbd3 (rhbd3) and to test the hypothesis that the antimicrobial characteristics of hbd3 may offer an advantage over conventional medicine in reducing intracanal bacteria. genetic engineering was used to obtain active rhbd3 and analysis revealed that it exhibited a broad spectrum of antibacterial activity at low micromolar concentrations agains ...	2009	18775647
tinidazole inhibitory and cidal activity against anaerobic periodontal pathogens.	the in vitro activity of tinidazole against anaerobic periodontal pathogens (25 prevotella buccae, 18 prevotella denticola, 10 prevotella intermedia, 6 prevotella melaninogenica, 5 prevotella oralis, 10 fusobacterium nucleatum and 8 veillonella spp.) was determined by agar dilution. mic(90) values (minimum inhibitory concentration for 90% of the organisms) were 8 microg/ml for veillonella spp., 4 microg/ml for p. intermedia, 2 microg/ml for p. buccae, 1 microg/ml for fusobacterium spp. and 0.5 m ...	2009	19097755
does pregnancy have an impact on the subgingival microbiota?	we investigated clinical and subgingival microbiologic changes during pregnancy in 20 consecutive pregnant women > or =18 years not receiving dental care.	2009	19228092
selective antibacterial and apoptosis-modulating activities of mastic.	mastic is a resinous exudate obtained from the stem and the main leaves of pistacia lentiscus. we have reported the antiplaque effect of mastic-containing chewing gum on the oral cavity. we hypothesize that mastic may be a multifunctional food which has some beneficial pharmaceutical properties. the aim of this study was to assess the biological activity of solid and liquid types of mastic by cytotoxicity against fibroblasts, radical-scavenging activities and inhibitory effect on cell death of o ...	2009	19414406
the microbiota on different oral surfaces in healthy children.	knowledge of the early oral colonization patterns could provide a better understanding of oral biofilm development and disease initiation that in turn could be the basis for early preventive programmes.	2009	19416446
methods for optimizing dna extraction before quantifying oral bacterial numbers by real-time pcr.	methods for the optimal extraction of genomic dna for real-time pcr enumeration of oral bacteria using the muramidase, mutanolysin, were developed using a simple in vitro oral flora model comprised of the facultative anaerobic gram-positive bacteria, lactobacillus acidophilus and streptococcus mutans, the gram-positive anaerobe, parvimonas micra, and the gram-negative anaerobes, porphyromonas gingivalis, prevotella melaninogenica and fusobacterium nucleatum. traditional, as well as more elaborat ...	2009	19459962
oral microbial and respiratory status of persons with mental retardation/intellectual and developmental disability: an observational cohort study.	the objective of this study was to determine the prevalence of select microorganisms in oral biofilms and to investigate relationships between oral and respiratory status in persons with mental retardation/intellectual and developmental disabilities (idd).	2009	19748295
uterine fibroid embolization.		2009	19967821
preliminary report on anaerobic culture at mymensingh medical college hospital in bangladesh.	puerperal sepsis is an important cause of maternal morbidity and mortality in developing countries. this study was undertaken to isolate and identify the anaerobic bacterial agents of puerperal sepsis among the patients admitted in mymensingh medical college hospital (mmch) during the period from july 2006 to june 2007. endocervical swabs/secretions were collected from 50 cases of puerperal sepsis and were cultured anaerobically. anaerobiasis was done by using gas pack (bd gas pak tm ez) in anae ...	2010	20046165
effects of ultrasonic, electric, and manual toothbrushes on subgingival plaque composition in orthodontically banded molars.	orthodontic appliances hinder mechanical plaque control. in this study, we evaluated the effect of self-performed supragingival plaque removal with ultrasonic, electric, and manual toothbrushes on subgingival plaque composition in orthodontically banded molars.	2010	20152680
evaluation of new gyrb-based real-time pcr system for the detection of b. fragilis as an indicator of human-specific fecal contamination.	a rapid and specific gyrb-based real-time pcr system has been developed for detecting bacteroides fragilis as a human-specific marker of fecal contamination. its specificity and sensitivity was evaluated by comparison with other 16s rrna gene-based primers using closely related bacteroides and prevotella. many studies have used 16s rrna gene-based method targeting bacteroides because this genus is relatively abundant in human feces and is useful for microbial source tracking. however, 16s rrna g ...	2010	20643165
trends in antibiotic resistance in prevotella species from patients of the university hospital of maxillofacial surgery, sofia, bulgaria, in 2003-2009.	head-and-neck infections often involve anaerobes such as prevotella species. aim of the present study was to assess the evolution and the factors associated with resistance in prevotella species to penicillin, clindamycin, metronidazole, tetracycline and β-lactams/β-lactamase inhibitors (bl/blis). in total, 192 prevotella strains, isolated from patients with oral and head-and-neck infections, were evaluated. common isolates were prevotella intermedia and prevotella melaninogenica within the pigm ...	2010	20670687
suppression of human immunodeficiency virus type 1 replication in macrophages by commensal bacteria preferentially stimulating toll-like receptor 4.	protection from primary human immunodeficiency virus type 1 (hiv-1) infection has not yet been accomplished by vaccines inducing hiv-1-specific acquired immunity. nevertheless, it has been reported that a small subgroup of women remain resistant to hiv-1 infection under natural conditions. if similar conditions can be induced in uninfected individuals, it will contribute the first line of protection against hiv-1 infection, and also improve the effects of anti-hiv-1 vaccines. we reasoned that in ...	2010	20719993
the role of bacteria in oral cancer.	despite the widening interest in the possible association between bacteria and different stages of cancer development, our knowledge in its relation to oral cancers remains inadequate. the aim of this review article is to derive a better understanding on the role of various micro-organisms in the etiogenesis of oral cancers through all the available data on the pubmed. different bacteria have been proposed to induce carcinogenesis either through induction of chronic inflammation or by interferen ...	2010	21584217
the identification of genes specific to prevotella intermedia and prevotella nigrescens using genomic subtractive hybridization.	prevotella intermedia and prevotella nigrescens, which are often isolated from periodontal sites, were once considered two different genotypes of p. intermedia. although the genomic sequence of p. intermedia was determined recently, little is known about the genetic differences between p. intermedia and p. nigrescens. the subtractive hybridization technique is a powerful method for generating a set of dna fragments differing between two closely related bacterial strains or species. we used subtr ...	2010	19931406
hematogenous long bone osteomyelitis by prevotella (bacteroides) melaninogenicus.	anaerobic infections are difficult to recognize and may lead to life threatening complications. we present the case of an acute prevotella hematogenous infection of the humerus in a previously healthy adult patient, treated with a two-stage surgical treatment, emphasizing on the importance of the radical surgical debridement and the selection of the appropriate antimicrobial agents. to our knowledge, such an acute hematogenous infection has not been previously reported in the literature. keyword ...	2010	22043262
variant of lemierre's syndrome secondary to trauma.	classic lemierre's syndrome is a septic internal jugular venous (ijv) thrombophlebitis secondary to oropharyngeal anaerobic infection in adolescent and young adult. though upper respiratory tract infection is the most common antecedent, it has also been described following skin, soft tissues, genitourinary and gastrointestinal infections. fusobacteria necrophorum is the commonest pathogen isolated from blood and tissue cultures but other bacteria like eikenella correndens, bacteroides melaninoge ...	2010	20886053
clinical characteristics and therapeutic outcome of gram-negative bacterial spinal epidural abscess in adults.	gram-negative (g(-)) bacterial spinal epidural abscess (sea) in adults is uncommon. of the 42 adult patients with bacterial sea admitted to the chang gung memorial hospital - kaohsiung, between 2003 and 2007, 12 with g(-) sea were included in this study. of these 12 patients, seven were men and five were women; their ages ranged between 17 years and 81 years (median=72.5 years, mean=62.5 years). the patients were admitted at different stages of symptom onset (four were in the acute stage and fou ...	2010	21185728
antimicrobial effectiveness of different preparations of calcium hydroxide.	background: intracanal medicaments have an antibacterial effect on the root canal flora. the effectiveness of such vehicles has to be tested and substantiated against the normal bacterial flora. the various vehicles that were tested for their effectiveness were commercially prepared calcium hydroxide (metapex), saline, glycerine, cmcp, and rexidine-m gel. the bacterial cultures tested for sensitivity were aerobes (staphylococcus aureus, streptococcus viridans, streptococcus pyogens, enterococcus ...	2011	21525680
botryomycosis presenting as nasal cutaneous fistulas caused by prevotella melaninogenica.	summary botryomycosis is an uncommon chronic suppurative granulomatous bacterial infection that can affect the skin and viscera. clinically, lesions typically consist of small tender nodules from which draining sinuses may develop to expel a purulent discharge. histopathological features include characteristic aggregation of microorganisms (grain) within the inflammatory infiltrate. the commonest causative organisms are staphylococcus aureus and pseudomonas aeruginosa, of others. botryomycosis r ...	2011	22212025
black stain - a review.	the purpose of this review was to summarise the fundamentals about black stain, its diagnosis and possible differential diagnoses as well as its microbiology and therapy. in addition, various studies investigating the relationship between black stain and dental caries are examined. many studies report lower caries prevalence in children with black stain, but this finding could not be confirmed by all authors. also, a negative relation between degree of staining and caries severity has been descr ...	2011	21594205
experimental alveolitis in rats: microbiological, acute phase response and histometric characterization of delayed alveolar healing.	the pathogenesis of alveolitis is not well known and therefore experimental situations that mimic some features of this disease should be developed.	2011	21625744
Early microbial succession in redeveloping dental biofilms in periodontal health and disease.	Teles FR, Teles RP, Uzel NG, Song XQ, Torresyap G, Socransky SS, Haffajee AD. Early microbial succession in redeveloping dental biofilms in periodontal health and disease. J Periodont Res 2011; doi: 10.1111/j.1600-0765.2011.01409.x. © 2011 John Wiley & Sons A/S Background and Objective: The development of dental biofilms after professional plaque removal is very rapid. However, it is not clear whether most bacterial species return at similar rates in periodontally healthy and periodontitis subj ...	2011	21895662
metaphylactic gamithromycin treatment for the management of lameness in ewes putatively caused by bacteroides melaninogenicus.		2011	21949059
a 6-month study of the effects of 0.3% triclosan/copolymer dentifrice on dental implants.	supportive therapy to maintain dental implants is increasingly important. this study examined the effect of a 0.3% triclosan/2% copolymer dentifrice on oral biofilms and gingival inflammation (gi) on dental implants and peri-implant tissues.	2011	20831669
prevotella fusca sp. nov. and prevotella scopos sp. nov., isolated from the human oral cavity.	two strains of anaerobic, gram-negative bacilli isolated from the human oral cavity were subjected to a comprehensive range of phenotypic and genotypic tests and were found to belong to two separate taxa. phylogenetic analysis of full-length 16s rrna gene sequences showed that the strains were both related to, but distinct from, the type strain of prevotella melaninogenica. two novel species, prevotella fusca sp. nov. and prevotella scopos sp. nov., are proposed to accommodate these strains. bot ...	2011	20495041
necrotizing periodontal diseases in hiv-infected brazilian patients: a clinical and microbiologic descriptive study.	objective: nowadays, necrotizing periodontal diseases have a low prevalence; however, a better understanding of the etiopathogenesis of these diseases is necessary for determining more adequate preventive and therapeutic strategies. method and materials: from a pool of 1,232 hiv-infected patients, 15 presented with necrotizing periodontal diseases, which were evaluated by full-mouth periodontal clinical measurements. subgingival biofilm samples were collected from necrotizing lesions of six of t ...	2012	22259811
[distribution of anaerobes in periodontal abscess and its resistance to antibiotics].	to isolate and culture the predominant anaerobes from the periodontal abscesses, and to test the antibiotic susceptibility and drug resistant genes of the strains.	2012	23328096
effects of hyperbaric oxygen on aggressive periodontitis and subgingival anaerobes in chinese patients.	to investigate the effects of hyperbaric oxygen (hbo2) on aggressive periodontitis (agp), and subgingival obligate anaerobes in chinese patients.	2012	23493978
microbial transformation from normal oral microbiota to acute endodontic infections.	endodontic infections are a leading cause of oro-facial pain and tooth loss in western countries, and may lead to severe life-threatening infections. these infections are polymicrobial with high bacterial diversity. understanding the spatial transition of microbiota from normal oral cavities through the infected root canal to the acute periapical abscess can improve our knowledge of the pathogenesis of endodontic infections and lead to more effective treatment. we obtained samples from the oral ...	2012	22839737
does periodontopathic bacterial infection contribute to the etiopathogenesis of the autoimmune disease rheumatoid arthritis?	there is a significant association between rheumatoid arthritis (ra) and periodontal disease (pd). patients with longstanding active ra have been found to have a substantially increased frequency of pd compared with healthy subjects. further, patients with pd have been shown to have a higher prevalence of ra than patients without periodontitis. antibodies to gram-negative, anaerobic periodontal pathogens such as porphyromonas gingivalis, prevotella intermedia, prevotella melaninogenica, and tann ...	2012	22642916
the short-term treatment effects on the microbiota at the dorsum of the tongue in intra-oral halitosis patients--a randomized clinical trial.	this study aims to assess the effects of rinsing with zinc- and chlorhexidine-containing mouth rinse with or without adjunct tongue scraping on volatile sulfur compounds (vscs) in breath air, and the microbiota at the dorsum of the tongue.	2013	22573244
the effects of airway microbiome on corticosteroid responsiveness in asthma.	the role of airway microbiome in corticosteroid response in asthma is unknown.	2013	24024497
discovery of β-1,4-d-mannosyl-n-acetyl-d-glucosamine phosphorylase involved in the metabolism of n-glycans.	a gene cluster involved in n-glycan metabolism was identified in the genome of bacteroides thetaiotaomicron vpi-5482. this gene cluster encodes a major facilitator superfamily transporter, a starch utilization system-like transporter consisting of a tonb-dependent oligosaccharide transporter and an outer membrane lipoprotein, four glycoside hydrolases (α-mannosidase, β-n-acetylhexosaminidase, exo-α-sialidase, and endo-β-n-acetylglucosaminidase), and a phosphorylase (bt1033) with unknown function ...	2013	23943617
subgingival microflora in inflammatory bowel disease patients with untreated periodontitis.	to analyze the subgingival microflora composition of inflammatory bowel disease (ibd) patients with untreated chronic periodontitis and compare them with systemically healthy controls also having untreated chronic periodontitis.	2013	23060013
sequences of multiple bacterial genomes and a chlamydia trachomatis genotype from direct sequencing of dna derived from a vaginal swab diagnostic specimen.	ultra-deep illumina sequencing was performed on whole genome amplified dna derived from a chlamydia trachomatis-positive vaginal swab. alignment of reads with reference genomes allowed robust snp identification from the c. trachomatis chromosome and plasmid. this revealed that the c. trachomatis in the specimen was very closely related to the sequenced urogenital, serovar f, clade t1 isolate f-sw4. in addition, high genome-wide coverage was obtained for prevotella melaninogenica, gardnerella vag ...	2013	23647919
prevotella jejuni sp. nov., isolated from the small intestine of a child with coeliac disease.	five obligately anaerobic, gram-stain-negative, saccharolytic and proteolytic, non-spore-forming bacilli (strains cd3 : 27, cd3 : 28(t), cd3 : 33, cd3 : 32 and cd3 : 34) are described. all five strains were isolated from the small intestine of a female child with coeliac disease. cells of the five strains were short rods or coccoid cells with longer filamentous forms seen sporadically. the organisms produced acetic acid and succinic acid as major metabolic end products. phylogenetic analysis bas ...	2013	23793857
molecular mapping to species level of the tonsillar crypt microbiota associated with health and recurrent tonsillitis.	the human palatine tonsils, which belong to the central antigen handling sites of the mucosal immune system, are frequently affected by acute and recurrent infections. this study compared the microbiota of the tonsillar crypts in children and adults affected by recurrent tonsillitis with that of healthy adults and children with tonsillar hyperplasia. an in-depth 16s rrna gene based pyrosequencing approach combined with a novel strategy that included phylogenetic analysis and detection of species ...	2013	23437130
description of alloprevotella rava gen. nov., sp. nov., isolated from the human oral cavity, and reclassification of prevotella tannerae moore et al. 1994 as alloprevotella tannerae gen. nov., comb. nov.	five strains of anaerobic, gram-negative bacilli isolated from the human oral cavity were subjected to a comprehensive range of phenotypic and genotypic tests and were found to comprise a homogeneous group. phylogenetic analysis of full-length 16s rrna gene sequences showed that these strains represented a novel group within the family prevotellaceae, and the most closely related species was prevotella tannerae. p. tannerae and the novel taxon are deeply branched from the genus prevotella, with ...	2013	22753527
exome capture from saliva produces high quality genomic and metagenomic data.	targeted capture of genomic regions reduces sequencing cost while generating higher coverage by allowing biomedical researchers to focus on specific loci of interest, such as exons. targeted capture also has the potential to facilitate the generation of genomic data from dna collected via saliva or buccal cells. dna samples derived from these cell types tend to have a lower human dna yield, may be degraded from age and/or have contamination from bacteria or other ambient oral microbiota. however ...	2014	24708091
bacteriological evaluation of tonsillar microbial flora according to age and tonsillar size in recurrent tonsillitis.	although numerous studies based on the bacteriology of the tonsil have been carried out, none of them analyzed the variation of tonsillar flora with respect to both age and tonsillar size. the purpose of this study was to isolate the facultative and obligate anaerobes both from the surface and the core of tonsils in recurrent tonsillitis as well as to analyze the variation of isolated bacterial strains according to age and tonsillar size. a prospective study was performed on 111 patients who und ...	2014	24487459
lactobacillus brevis cd2 inhibits prevotella melaninogenica biofilm.	to evaluate the ability of the probiotic strain lactobacillus brevis cd2 to inhibit the opportunistic anaerobe prevotella melaninogenica (pm1), a well-known causative agent of periodontitis.	2014	24118283
microbial profile of root canals of primary teeth with pulp necrosis and periradicular lesion.	the purpose of this study was to assess the microbial content of root canals of human primary teeth with pulp necrosis and periradicular lesion.	2014	24709428
a chlorhexidine-loaded biodegradable cellulosic device for periodontal pockets treatment.	absorbent points widely used in endodontic therapy were transformed into bioresorbable chlorhexidine delivery systems for the treatment of the periodontal pocket by preventing its recolonization by the subgingival microflora. these paper points (pps) were first oxidized to promote their resorption, then grafted with β-cyclodextrin (cd) or maltodextrin (md) in order to achieve sustained delivery of chlorhexidine. we investigated the oxidation step parameters through the time of reaction and the n ...	2014	24090988
liquid based microbiological transport systems: conformity assessment of two commercial devices.	we compared two types of liquid-based microbiology devices for microorganism viability according to standardized quantitative elution method clsi m40-a2. the eswab® met clsi acceptance criteria of viability maintenance for all microorganisms tested. the σ-transwab® failed to meet clsi acceptance criteria for peptostreptococcus anaerobius, prevotella melaninogenica, fusobacterium nucleatum and haemophilus influenzae.	2015	25957512
the effect of blue light on periodontal biofilm growth in vitro.	we have previously shown that blue light eliminates the black-pigmented oral bacteria porphyromonas gingivalis, prevotella intermedia, prevotella nigrescens, and prevotella melaninogenica. in the present study, the in vitro photosensitivity of the above black-pigmented microorganisms and four fusobacteria species (fusobacterium nucleatum ss. nucleatum, f. nucleatum ss. vincentii, f. nucleatum ss. polymorphum, fusobacterium periodonticum) was investigated in pure cultures and human dental plaque ...	2015	25759232
chronic obstructive pulmonary disease and asthma-associated proteobacteria, but not commensal prevotella spp., promote toll-like receptor 2-independent lung inflammation and pathology.	recent studies of healthy human airways have revealed colonization by a distinct commensal bacterial microbiota containing gram-negative prevotella spp. however, the immunological properties of these bacteria in the respiratory system remain unknown. here we compare the innate respiratory immune response to three gram-negative commensal prevotella strains (prevotella melaninogenica, prevotella nanceiensis and prevotella salivae) and three gram-negative pathogenic proteobacteria known to colonize ...	2015	25179236
effects of hangeshashinto on growth of oral microorganisms.	oral mucositis (om) in cancer patients induced by chemotherapy or radiotherapy has a significant impact on quality of life, and causes considerable morbidity. oral microorganisms are likely to intensify the inflammatory process and aggravate the formation of ulcers. hangeshashinto (hst), a japanese kampo medicine, has been reported to be effective when used as a gargle for the treatment of om. to clarify the effects of hst on oral microorganisms, we assessed its antimicrobial activity against 27 ...	2015	26170876
[noma/cancrum oris: a neglected disease].	noma is an aggressive orofacial gangrenous pathology that damages hard and soft tissues of the mouth and the face. throughout the centuries it has been present around the globe, but nowadays it has practically disappeared from developed countries and mainly affects children from the most disadvantaged places, especially in africa. noma disease is a multifactorial process; malnutrition, debilitating diseases (bacterial or viral systemic diseases, hiv-associated immunosuppression, etc.) and intrao ...	2015	26437752
[comparison study of oropharyngeal microbiota in case of bronchial asthma and chronic obstructive pulmonary disease in different severity levels].	the result of comparative study of oropharyngeal microbiota taxonomic composition in patients with different severity level of bronchial asthma (ba) and chronic obstructive pulmonary disease (copd) is presented in this paper.	2015	27093794
alterations in the mucosa-associated bacterial composition in crohn's disease: a pilot study.	changes in the intestinal bacterial composition seem to play a major role in the pathogenesis and in the clinical course of inflammatory bowel diseases (ibd), which consist of crohn's disease (cd), and ulcerative colitis (uc). mutations in the nod2 gene are the most important genetic risk factors for the development of cd. in this study, the association between mucosal biopsies and the mucosa-associated bacterial composition from cd and uc patients regarding their genetic risk factors (mutations ...	2016	26951181
polymicrobial pituitary abscess predominately involving escherichia coli in the setting of an apoplectic pituitary prolactinoma.	pituitary abscess is a rare intracranial infection that can be life-threatening if not appropriately diagnosed and treated upon presentation. the most common presenting symptoms include headache, anterior pituitary hypofunction, and visual field disturbances. brain imaging with either computed tomography or magnetic resonance imaging usually reveals intra- or suprasellar lesion(s). diagnosis is typically confirmed intra- or postoperatively when pathological analysis is done. clinicians should im ...	2016	27006841
does obesity influence the subgingival microbiota composition in periodontal health and disease?	to evaluate whether obesity affects the subgingival microbial composition of patients with periodontal health or chronic periodontitis (cp).	2016	27717180
species-level core oral bacteriome identified by 16s rrna pyrosequencing in a healthy young arab population.	reports on the composition of oral bacteriome in arabs are lacking. in addition, the majority of previous studies on other ethnic groups have been limited by low-resolution taxonomic assignment of next-generation sequencing reads. furthermore, there has been a conflict about the existence of a 'core' bacteriome.	2016	27193835
experimental conical-head abutment screws on the microbial leakage through the implant-abutment interface: an in vitro analysis using target-specific dna probes.	the aim of this in vitro study was to identify and quantify up to 38 microbial species from human saliva penetrating through the implant-abutment interface in two different implant connections, external hexagon and tri-channel internal connection, both with conventional flat-head or experimental conical-head abutment screws.	2016	27198721
influence of the periodontal status on the initial-biofilm formation on titanium surfaces.	dental implants will be exposed to a complex ecosystem once they are placed in the oral cavity. the bacterial colonization and biofilm formation on these devices will depend not only on the physicochemical surface implant properties but also on the periodontal health conditions of the patients, as these devices are exposed.	2016	24995517
taxa of the nasal microbiome are associated with influenza-specific iga response to live attenuated influenza vaccine.	live attenuated influenza vaccine (laiv) has demonstrated varying levels of efficacy against seasonal influenza; however, laiv may be used as a tool to measure interactions between the human microbiome and a live, replicating virus. to increase our knowledge of this interaction, we measured changes to the nasal microbiome in subjects who received laiv to determine if associations between influenza-specific iga production and the nasal microbiome exist after immunization with a live virus vaccine ...	2016	27643883
propolis, a hope for the future in treating resistant periodontal pathogens.	periodontitis is one of the most common causes of tooth loss worldwide. recently, special attention has been paid to natural medication for its treatment. for this purpose, propolis (bee glue) activity has also been investigated. its antibacterial properties are mainly attributed to flavonones pinocembrin, flavonols galangin and to the caffeic acid phenethyl ester. this study is aimed at evaluating the antimicrobial effects of propolis from pakistan on 35 clinical isolates of pigmented anaerobic ...	2016	27563508
microbiological and bioinformatics analysis of primary sjogren's syndrome patients with normal salivation.	reduced salivation is considered a major clinical feature of most but not all cases of primary sjögren's syndrome (pss). reduced saliva flow may lead to changes in the salivary microbiota. these changes have mainly been studied with culture that typically recovers only 65% of the bacteria present.	2016	27770517
a case of pituitary abscess presenting without a source of infection or prior pituitary pathology.	pituitary abscess is a relatively uncommon cause of pituitary hormone deficiencies and/or a suprasellar mass. risk factors for pituitary abscess include prior surgery, irradiation and/or pathology of the suprasellar region as well as underlying infections. we present the case of a 22-year-old female presenting with a spontaneous pituitary abscess in the absence of risk factors described previously. her initial presentation included headache, bitemporal hemianopia, polyuria, polydipsia and amenor ...	2016	27555916