Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| a genetic linkage map of human chromosome 9q. | a genetic linkage map of human chromosome 9q, spanning a sex-equal distance of 125 cm, has been developed by genotyping 26 loci in the venezuelan reference pedigree. the loci include 12 anonymous microsatellite markers reported by kwiatkowski et al. (1992), several classical systems previously assigned to chromosome 9q, and polymorphisms for the genes tenacin (hxb), gelsolin (gsn), adenylate kinase 1 (ak1), arginosuccinate synthetase (ass), abl oncogene (abl1), abo blood group (abo), and dopamin ... | 1992 | 1427899 |
| adaptation and recovery from adaptation of the auditory nerve neurophonic (ann) using long duration tones. | the time course of the interaction between adaptation and the recovery from adaptation of the auditory nerve neurophonic (ann) responses was examined. the interaction between the process of recovery and the adaptation process of long probe tones which follow a masker, the so called whole tone recovery, was determined for the ann response for different silent intervals between masker offset and probe onset. the auditory nerve neurophonic (ann) reflects the ensemble response of phase-locked firing ... | 1992 | 1429255 |
| in vitro culture of the strobilar stage of echinococcus granulosus of sheep and donkey origin from jordan. | protoscolices of echinococcus granulosus isolated from hydatid cysts of sheep and donkeys in jordan were cultured in vitro using a modified diphasic culture system. protoscolices from these two sources manifested differences in the mode of development, evagination and growth rates. protoscolices isolated from sheep cysts grew in vitro in the polyzoic direction up to the three- to four-segmented mature worms, reaching a length of 2.9 mm. in contrast, donkey protoscolices failed to develop beyond ... | 1992 | 1438153 |
| cutaneous leishmaniasis in western venezuela caused by infection with leishmania venezuelensis and l. braziliensis variants. | between 1975 and 1987, epidemiological studies were carried out in several rural and urban communities in the central part of western venezuela, especially in the state of lara. 115 positive cultures were obtained from human cases and identified by their reactivity patterns to a cross-panel of specific monoclonal antibodies using a radioimmune binding assay; 53 were leishmania venezuelensis and 62 were l. braziliensis. most of these stocks were also characterized by isoenzyme electrophoresis, wh ... | 1992 | 1440772 |
| genetic evidence that epizootic venezuelan equine encephalitis (vee) viruses may have evolved from enzootic vee subtype i-d virus. | an important question pertaining to the natural history of venezuelan equine encephalitis (vee) virus concerns the source of epizootic, equine-virulent strains. an endemic source of epizootic virus has not been identified, despite intensive surveillance. one of the theories of epizootic strain origin is that epizootic vee viruses evolve from enzootic strains. likely enzootic sources of vee virus occur in colombia and venezuela where many of the epizootic outbreaks of vee have occurred. we have d ... | 1992 | 1448915 |
| high sensitivity of human melanoma cell lines to the growth inhibitory activity of mycoplasmal arginine deiminase in vitro. | arginine deiminase (ad) is a potent growth inhibitor for some but not all tumour cell lines in vitro. as ad catalyses the direct conversion of l-arginine to l-citrulline, the ad-sensitivity of various tumour cells might be attributed to the levels of urea cycle enzymes involved in l-arginine biosynthesis. this study demonstrated that human melanoma cells were highly sensitive to the growth inhibitory activity of ad. five melanoma cell lines tested also exhibited reduced argininosuccinate synthet ... | 1992 | 1450673 |
| studies on rhinoestrus purpureus (diptera: oestridae) larvae infesting donkeys (equus asinus) in egypt. iii. pupal duration under controlled conditions. | the pupal duration of rhinoestrus purpureus was studied under variable degrees of temperature and relative humidity (rh). it was found that pupal duration was affected by temperature but not by rh. an increase in the temperature above 22 degrees c decreased the pupal duration: 26-27 days at 22 degrees c, 16-24 days at 27 degrees c, 13-15 days at 32 degrees c. at 37 degrees c, the pupated larvae failed to pupate and died. the deformity ratio of emerged flies was 25-30% at 22-32 degrees c, but it ... | 1992 | 1466135 |
| epidemiological observations on stomach worms of donkeys in morocco. | over two consecutive years, weekly examinations for the presence of nematodes were conducted on 185 stomachs from donkeys originating mainly from the rabat, casablanca and settat regions of morocco. all the animals, except one, were infected by at least one of four helminth species. trichostrongylus axei was found in 93.5%, habronema muscae in 89.7%, h. majus in 85.4% and draschia megastoma in 1.1% of donkeys. most animals were infected by two (23.8%) or three (71.9%) species. high burdens of t. ... | 1992 | 1466146 |
| the amino-acid sequence of two isoforms of alpha-lactalbumin from donkey (equus asinus) milk is identical. | the complete primary structure of donkey alpha-lactalbumin a and b has been determined by sequencing of the peptides obtained after tryptic, glu-c proteinase or cyanogen bromide cleavage. although preparative purification of alpha-lactalbumin by flat-bed isoelectric focusing gave two protein fractions a and b, their amino-acid sequence revealed no differences. donkey alpha-lactalbumin shows two, four and five differences in comparison to the horse alpha-lactalbumin a, b and c. thus donkey alpha- ... | 1992 | 1466791 |
| elevated gene expression of argininosuccinate synthetase in peripheral lymphocytes from systemic lupus erythematosus (sle) patients. | argininosuccinate synthetase (ass) is a rate-limiting enzyme of urea cycle and functions primarily in the liver, whereas ass activity is hardly detected in normal lymphocytes. in this study, we examined the level of ass gene expression in peripheral blood lymphocytes (pbl) from human sle patients by amplification of reverse-transcribed mrna using the polymerase chain reaction. we have demonstrated that (a) approximately 40% of sle patients exhibited 2.5 to 5 times higher expression of ass gene i ... | 1992 | 1467433 |
| molecular evidence for the origin of the widespread venezuelan equine encephalitis epizootic of 1969 to 1972. | venezuelan equine encephalitis (vee) virus is a mosquito-borne pathogen that has caused encephalitis in equine species and humans during sporadic outbreaks in the western hemisphere. the last, and most widespread, vee outbreak occurred in south america, central america, mexico and the u.s.a. (texas) during 1969 to 1972. we have cloned and sequenced the genome of a virulent vee subtype i-ab virus, strain 71-180, isolated in texas in 1971. thirty-four nucleotide differences were detected between t ... | 1992 | 1469368 |
| african horse sickness in spain. | the aetiology, pathogenesis and epizootiology of african horse sickness (ahs) are reviewed with special reference to recent outbreaks in the iberian peninsula. ahs is a highly fatal insect-borne viral disease of equidae. it is caused by an orbivirus (family reoviridae) and nine serotypes are recognised. outbreaks occurred in central spain in 1987 and in southern regions of the iberian peninsula in 1988, 1989 and 1990. all were associated with serotype 4 of the virus, whereas other occurrences of ... | 1992 | 1481352 |
| the psychoanalytic setting as the instrument of the container function. | different settings reveal the operation of different psychical mechanisms; for this reason i try in this paper to take a fresh look at the psychoanalytic setting which underlies the specificity of what we psychoanalysts call psychoanalysis and helps to distinguish it from other forms of therapy--in particular, psychotherapy. in my view, the analyst's creative container function is expressed particularly through the setting. this setting is not an inert vessel, a mere juxtaposition of rules, but ... | 1992 | 1483843 |
| [median-term (4 months) treatment with glibenclamide + metformin substituting for glibenclamide + fenformin lowers the lacticemia levels in type-2 diabetics (niddm)]. | 60 niddm patients, mean age (68 +/- 3 years), bmi (25 +/- 5.1 kg/m2), fasting blood glucose (fg) (170 +/- 10 mg/dl), mean daily blood glucose (mdbg) (180 +/- 10 mg/dl), daily glycosuria (glu) (15.6 +/- 9 g/24 hours), hba1c (7.9 +/- 0.6%), basal (1.2 +/- 0.2 ng/ml) and stimulated (3.89 +/- 1.3 mg/ml) c peptide (cp) treated by ass (7.5 +/- 75 mg), after a strict 4 months follow-up period, were assigned to g + m treatment (7.5 +/- 1.500 mg) during a 4 months period. during g+m treatment fg (171 +/- ... | 1992 | 1493670 |
| [the selenium content in the blood of newborn sheep and goats--equally contributing to the effect of supplemental oral selenium as a prophylaxis]. | the article is based on the analysis of selenium concentration in blood plasma of 9 goats and their kids (n = 17), from two different places, as well as of 12 sheep and their lambs (n = 19) from several flocks. the selenium concentration was measured using ass. in addition, the activity of ck was determined enzymatically. there was a low plasma selenium level in lambs and goat kids immediately post-natal depending on the selenium state of the mothers. after application of vitamin e and selenium ... | 1992 | 1496519 |
| epidemiological observations on gasterophilus intestinalis and g. nasalis in donkeys from morocco. | during a 24 month period, 198 donkeys were examined for gasterophilus intestinalis and gasterophilus nasalis larvae. gasterophilus intestinalis was found in 97.5% and g. nasalis in 95.5% of donkeys. the third instars (l3) of both species occurred during all months of the year and so did the second instars (l2), except in april (g. nasalis) and may (g. intestinalis). over 75% of the animals had up to 200 larvae and 1.5% had over 600 larvae. the maximum number of both l2 and l3 larvae found in any ... | 1992 | 1502790 |
| [surgical removal of a pedunculated uterine tumor in a donkey mare]. | the unusual incidence of a pedunculated fibrosarcoma in the uterus of a donkey is reported. the tumor caused colic-like symptoms and blood tinged vaginal discharge. the diagnosis was made by ultrasound and rectal examination. the patient was successfully treated surgically, by ovariohysterectomy. | 1992 | 1509483 |
| last chance for british ass? | 1992 | 1522874 | |
| [risks and benefits of thrombendarterectomy in bilateral internal carotid artery stenosis]. | among the patients who were operated for cerebrovascular insufficiency, one third suffered from bilateral stenoses of the internal carotid artery. in a retrospective analysis of 47 patients who were operated in consecution and of 28 patients who refused operation and were treated conservatively, the outcome was compared to cases with a one-sided stenosis. 31 patients were operated on one side and 16 on both sides. 28 of the surgically treated cases were followed up for an average of 32 months. t ... | 1992 | 1529632 |
| the 'natural' hybrid haemoglobin from mule. interrelationships with its parent haemoglobins from horse and donkey. | the equilibrium o2-binding properties of the hybrid haemoglobin (hb) present in vivo in erythrocytes from mule and of its parent hbs from horse and donkey were compared with special reference to the effect of heterotropic ligands such as cl-, d-glycerate 2,3-bisphosphate (dpg) and inositol hexakisphosphate. all these hbs display a decreased effect by polyphosphates, confirming that what has been observed for horse hb [giardina, brix, clementi, scatena, nicoletti, cicchetti, argentin & condò (199 ... | 1992 | 1546974 |
| transmission of venezuelan equine encephalomyelitis virus by aedes sollicitans and aedes taeniorhynchus (diptera: culicidae). | experimental studies compared the vector competence of aedes sollicitans (skuse) and ae. taeniorhynchus (wiedemann) collected on assateague island, va., for an epizootic strain (trinidad donkey) of venezuelan equine encephalomyelitis (vee) virus. infection rates were significantly higher in ae. sollicitans (101/107, 94%) than in ae. taeniorhynchus (103/175, 59%), even though both species fed concurrently on the same infected hamsters. similarly, dissemination and transmission rates were signific ... | 1992 | 1552530 |
| lysinuric protein intolerance presenting deficiency of argininosuccinate synthetase. | a 35-yr-old woman, who suffered from relapsing coma with hyperammonemia for 17 yr, was diagnosed to have lysinuric protein intolerance (lpi). increased urinary dibasic amino acids (lysine, arginine and ornithine) and impaired absorption of orally administered lysine and arginine proved the defects of renal tubular and intestinal transport of dibasic amino acids. these defects are the primary cause of impaired urea cycle metabolism in lpi. further, the level of argininosuccinate synthetase (ass), ... | 1992 | 1568044 |
| enhanced clearance of radiolabeled murine monoclonal antibody by a syngeneic anti-idiotype antibody in tumor-bearing nude mice. | a syngeneic anti-idiotype monoclonal antibody (mab) (cm-11) directed against an anti-carcinoembryonic antigen (cea) murine mab (np-4) was evaluated as a second antibody (sa) to promote the rapid clearance of radiolabeled np-4 from the blood. initial studies confirmed that cm-11 igg removed 131i-np-4 igg from the blood as effectively as a polyclonal donkey anti-goat igg removed 131i-goat igg. however, use of an f(ab')2 in place of either the np-4 or cm-11 igg was not as effective in removing prim ... | 1992 | 1568794 |
| the application of a novel biotinylated affinity label for the detection of a cathepsin b-like precursor produced by breast-tumour cells in culture. | in this report we demonstrate how the recently developed biotinylated affinity label biotinyl-phe-ala-diazomethane (bio-phe-ala-chn2) [cullen, mcginty, walker, nelson, halliday, bailie & kay (1990) biochem. soc. trans. 18, 315-316; walker, cullen, kay, halliday, mcginty & nelson (1992) biochem. j. 283, 449-453] can be used for the detection of a precursor form of a cathepsin b-like enzyme produced by breast-tumour cells in culture. thus the cell lines mda-mb-436, zr-75-1 and t47-d produce a solu ... | 1992 | 1575692 |
| normal and abnormal sexual behavior. | this article includes a brief description of the reproductive patterns and specific behaviors comprising courtship and copulation in equids. the author then focuses on breeding behavior of the domestic stallion. descriptions of normal breeding behavior under a variety of domestic management systems, comments on sexual behavior of donkeys and exotic equids, and the most common types and treatments of sexual behavior dysfunction are included. | 1992 | 1576555 |
| radioimmunoassay that measures serum vitamin b12. | to develop a specific radioimmunoassay for the routine determination of serum vitamin b12. | 1992 | 1577970 |
| cloning and characterization of the cdna encoding human adenylosuccinate synthetase. | adenylosuccinate synthetase (as) catalyzes the first committed step in the conversion of imp to amp. a cdna was isolated from a human liver library which encodes a protein of 455 amino acids (m(r) of 49,925). alignments of human, mouse, dictyostelium discoideum and e. coli as sequences identify a number of invariant residues which are likely to be important for structure and/or catalysis. the human as sequence was also 19% identical to the human urea cycle enzyme, argininosuccinate synthetase (a ... | 1992 | 1592113 |
| use of ass' milk in multiple food allergy. | we report a study of realimentation techniques in 9 unweaned infants with multiple food hypersensitivity. the patients had presented severe symptoms of cow's milk allergy and successive attempts using milk containing soy protein and/or a semielemental formula in their alimentation did not improve their clinical condition, due to the onset of hypersensitivity to these allergens as well. after a short period of parenteral alimentation the infants were refed per os with ass' milk (250 ml/kg/day) + ... | 1992 | 1593372 |
| argininosuccinate synthetase gene expression in leukemias: potential diagnostic marker for blastic crisis of chronic myelocytic leukemia. | argininosuccinate synthetase (ass) activity is hardly detected in human lymphocytes. in this study, we examined the ass gene expression of various leukemia cells by a polymerase-chain-reaction method. we demonstrate here that (a) acute lymphocytic and acute myelocytic leukemia cells exhibit the highly elevated expression of the ass gene and (b) chronic myelocytic leukemia (cml) in blastic crisis also exhibits the increase of ass gene expression while cml in chronic phase, chronic lymphocytic leu ... | 1992 | 1625473 |
| arthrodesis for congenital flexural deformity of the metacarpophalangeal and metatarsophalangeal joints. | a llama, a miniature horse, and a miniature donkey with severe bilateral congenital flexural deformities of the metacarpophalangeal and metatarsophalangeal joints were treated successfully by arthrodesis with dynamic compression plating or external skeletal fixation. the flexor tendons were more taut than the suspensory ligaments and were transected. in the llama, the suspensory ligament was transected, and overcorrection caused ischemic necrosis of one distal limb and subluxation of the other f ... | 1992 | 1626399 |
| hysteroscopic sterilization. | after a brief history of sterilization, this article is devoted to hysteroscopic techniques and instrumentation, and a presentation of hysteroscopic sterilization techniques: electrocoagulation techniques, hysteroscopic injection of chemicals, and hysteroscopically directed placement of intratubal mechanical devices (ceramic plugs, polyethylene plugs, preformed silicone plugs, nylon intratubal plugs, and formed-in-place silicone rubber plugs. problems are identified that are common to all hys ... | 1992 | 1638821 |
| disposition of ampicillin sodium in horses, ponies and donkeys after intravenous administration. | 1992 | 9109963 | |
| energy reserves and parity of nomadic and settled turkana women. | members of the turkana tribe include settled and nomadic peoples who reside in the southern part of turkana district in the semiarid region of northwest kenya. nomadic ngisonyoka turkana keep livestock (camels, cattle, sheep, goats, donkeys), subsist principally on livestock products, and move camps frequently in search of forage for the livestock; settled turkana cultivate foods along the principal rivers. both nomadic and settled turkana are subject to limited food resources on seasonal and lo ... | 1992 | 28524637 |
| estimating the bodyweight of donkeys. | 1993 | 8460461 | |
| attenuation of venezuelan equine encephalitis virus strain tc-83 is encoded by the 5'-noncoding region and the e2 envelope glycoprotein. | the virulent trinidad donkey (trd) strain of venezuelan equine encephalitis (vee) virus and its live attenuated vaccine derivative, tc-83 virus, have different neurovirulence characteristics. a full-length cdna clone of the tc-83 virus genome was constructed behind the bacteriophage t7 promoter in the polylinker of plasmid puc18. to identify the genomic determinants of tc-83 virus attenuation, trd virus-specific sequences were inserted into the tc-83 virus clone by in vitro mutagenesis or recomb ... | 1993 | 7679745 |
| neuronal responses to vestibular and callosal stimulation in the anterior suprasylvian gyrus of the cat. | neuronal responses to electrical stimulation at the horizontal ampulla (ha), vestibular nerve (at the windows) and corpus callosum (cc) were investigated in neurons in the anterior suprasylvian gyrus of the cat. the field potentials to ha stimulation had short latency: 2.9 +/- 0.3 (mean +/- sd) ms from the stimulus to the onset and 5.6 +/- 1.9 ms to the peak. the focus of the evoked potentials was located in the anterior suprasylvian (ass) gyrus or near the ass sulcus. ha stimulation activated 6 ... | 1993 | 7683394 |
| [serum argininosuccinate synthetase (ass) in patients with chronic hepatitis c treated with interferon]. | serum ass and serum gpt levels were determined in 16 patients with chronic hepatitis c treated with interferon. in all the patients, the serum ass level decreased earlier than the serum gpt level, and this tendency was remarkable in patients who excellently responded to the treatment. furthermore, the serum ass level was fluctuated when the serum gpt levels being continuously flat in the course of the treatment, probably because of the shorter half life of ass in the serum. in conclusion, the se ... | 1993 | 7685731 |
| kinetics of interaction of hiv reverse transcriptase with primer/template. | intrinsic protein fluorescence of reverse transcriptases from hiv-1 and hiv-2 provides a sensitive signal for monitoring the interaction of the enzymes with primer/template duplex molecules. kd values for 18/36-mer dna/dna duplexes were found to be in the range of a few nanomolar (about 3 times higher for the enzyme from hiv-2 than for that from hiv-1). the quenching of protein fluorescence induced on binding primer/template, together with an increase in extrinsic fluorescence on interaction wit ... | 1993 | 7688571 |
| village health survey of sina mala, gongola state, nigeria. | a survey of the environment, life-style, and health status, knowledge, attitudes and practices in the village of sina mala was carried out prior to the introduction of a village health post by a church-run rural health programme. in addition to the perceived needs of the villagers for a school, easier access to medicine and external assistance with well drilling, the study identified the need to train traditional midwives in hygienic delivery, to make local health workers more aware of onchocerc ... | 1993 | 7839910 |
| characterization of chromosome 9 deletions in transitional cell carcinoma by microsatellite assay. | a panel of 18 superficial or invasive transitional cell carcinomas (tccs) was analyzed for chromosome 9 deletions by performing a high-density loss of heterozygosity (loh) analysis. twenty-five microsatellite loci were assayed by the polymerase chain reaction (pcr) and 7 restriction fragment length polymorphism (rflp) loci were analyzed by southern blotting. concordant results were obtained with these methods, including direct comparisons at 2 loci. chromosome 9 loh was observed in 13 (72%) of 1 ... | 1993 | 7902161 |
| field observations in israel on hypersensitivity in cattle, sheep and donkeys caused by culicoides. | hypersensitive lesions in the skin of sheep, cattle and donkeys from various regions in israel are described. no cause other than insect bites was found. the animals were free of ticks, lice, fleas and blackflies, and of all the prevailing insect groups; culicoides spp were considered as the most probable cause of the hypersensitivity. lesions on the legs and abdomen were attributed mainly to c obsoletus meigen, c schultzel gp and c puncticollis becker, and less to c imicola kieffer. lesions on ... | 1993 | 8240175 |
| stomach parasites of donkeys in morocco: habitat and interspecific interactions. | one hundred and four donkeys originating from several regions of morocco were necropsied during 1 year. the parasites in their stomachs were counted and locations determined in the cardiac, fundic and pyloric portions. synergistic or antagonistic interactions between parasites were assessed by a principal component analysis. gasterophilus intestinalis was only found in the cardiac portion and g. nasalis was mostly found in the pyloric portion. habronema were principally encountered in the pylori ... | 1993 | 8249256 |
| [parasitological fecal studies of equids, dogs, cats and hedgehogs during the years 1984-1991]. | the results of the coproscopical examinations in horses, dogs, cats and hedgehogs between 1984 and 1991 are presented. in 9192 samples from horses 55.5% stages of strongylids, 4.0% of parascaris equorum, 2.2% of anoplocephalids, 1.6% strongyloides westeri, 0.7% of oxyuris equi, 0.6% of eimeria leuckarti, 0.2% of fasciola hepatica and 0.04% of dictyocaulus arnfieldi were found. in 48.0% of the 46 samples from donkeys eggs from strongylids were detected, in 17.4% larvae from dictyocaulus arnfieldi ... | 1993 | 8261912 |
| pig leukocyte cysteine proteinase inhibitor (plcpi), a new member of the stefin family. | a new stefin type low-m(r) cysteine proteinase inhibitor (plcpi) was isolated from pig polymorphonuclear leukocytes as a contaminant of the cathelin sample. the inhibitor consists of 103 amino acids, and its m(r) was calculated to be 11,768. the inhibitor exhibits considerable sequence identity with inhibitors from the stefin family, particularly with human stefin a. the plcpi is a fast acting inhibitor of papain and cathepsins l and s (k(ass) > or = 1 x 10(6) m-1 x s-1) and forms very tight com ... | 1993 | 8262248 |
| tamm-horsfall glycoprotein binds igg with high affinity. | tamm-horsfall protein (thp), a monomeric glycoprotein (m(r) 80 to 100 kda), is produced by the mammalian kidney's thick ascending limb of henle cells and excreted into the urine. the function of thp is uncertain. here we report that a high molecular weight contaminant in sheep thp (sthp) preparations was identified as sheep igg by its positive reaction with donkey anti-sheep igg antibody and with protein g. to answer the question of whether sthp and sheep igg co-purified because of a physical in ... | 1993 | 8264130 |
| virucidal activity of an activated sludge supernatant. | the virucidal activity of the activated sludge aqueous phase was studied from the time of initial inoculation with a poliovirus type 1 suspension and for durations of three and nine days. the mixtures were incubated in presence of a nutritive medium at 26 degrees c and samples were drawn at regular intervals of time for viral titration. the activated sludge supernatant (ass) caused an important decrease of the titer of the poliovirus type 1 suspension especially after nine days of incubation. th ... | 1993 | 8267834 |
| rapid evolution of horse satellite dna. | the major satellite of the horse genome consists of about 1 million copies of a 221-bp tandem repeat unit. by fluorescence in situ hybridization it has been localized in the centromeres of 58 of the 64 horse chromosomes. the donkey genome contains a similar but not identical satellite. strikingly, the equine repeat did not hybridize to dna of the grevy zebra, despite the divergence of the horse and zebra only 3 to 5 million years ago and the ability of these species to crossbreed. the evolution ... | 1993 | 8276394 |
| purification and quantitative measurement of bovine serum amyloid-a. | bovine serum amyloid-a (b-saa) was purified from a pool of acute phase serum using hydrophobic interaction chromatography and gel filtration. serum was applied at a low salt concentration to a phenyl-sepharose column and saa was eluted with a gradient of 0 to 6 m guanidine-hcl. fractions containing saa were pooled, concentrated and further purified by gel filtration on superose-12. the concentration of saa in bovine serum was quantified by an indirect elisa using rabbit anti-human saa and horser ... | 1993 | 8284495 |
| [the immunogenic properties of a recombinant vaccinia virus with an incorporated dna copy of the 26s rna of the venezuelan equine encephalomyelitis virus]. | a recombinant strain of vaccinia virus (vr26) containing a dna-copy of the subgenomic 26s rna of venezuelan equine encephalomyelitis virus (vee) inserted into the coding region of thymidine kinase (tk) gene was produced. this subgenomic rna contained the genes for all structural proteins of the vee virus, the strain trinidad donkey (trd). vr26 effectively expressed vee virus glycoproteins on the membranes of the infected cells. blood sera of vr26-immunized animals were found to contain vee virus ... | 1993 | 8284922 |
| sympathetic denervation of the epicardial border zone in the genesis of dispersion of refractoriness and arrhythmogenesis in a 7-day-old canine myocardial infarction model. | the purpose of this study was to clarify whether sympathetic denervation occurs in the infarcted heart and contributes to the dispersion of the effective refractory period (erp) and arrhythmogenesis. | 1993 | 8287211 |
| linkage analysis of infantile pyloric stenosis and markers from chromosome 9q11-q33: no evidence for a major gene in this candidate region. | a genetic component in the aetiology of infantile pyloric stenosis (ps) is well established. segregation analysis is compatible with a multifactorial sex modified threshold model of inheritance but a major gene of low penetrance has not been excluded. ps has been reported to occur in 57% (four of seven) of cases with duplication of chromosome 9q11-q33. twenty families with ps were studied using genetic markers at loci d9s55, d9s111, d9s15, d9s12, d9s56, d9s59, and ass from this region of chromos ... | 1993 | 8320701 |
| [study on determination of gentamycin by enhanced chemiluminescent immunoassay]. | gentamycin was determined by solid antigen competition inhibition method of chemiluminescet immunoassay, in which luminol-(p-hydroxydiphenyl)-h2o2 was used a the chemiluminescence system and p-hydroxydiphenyl as the chemiluminescent enhancer. solid antigen was synthesized by a method in which gentamycin was immobilized covalently on microcrystalline cellulose previously activated by 1,1'-carbonyldiimidazole. the rabbit anti-gentamycin igg and the hrp-donkey anti-rabbit igg were used as the first ... | 1993 | 8340080 |
| linkage analysis with chromosome 9 markers in hereditary essential tremor. | hereditary essential tremor (et) is an autosomal dominant disorder with variable expression and reduced penetrance. a tremor indistinguishable from et may be observed in patients with autosomal dominant idiopathic torsion dystonia (itd), in which the disease locus has been mapped to 9q32-34 in some kindreds, tightly linked to the argininosuccinate synthetase (ass) locus. we performed linkage analysis in 15 families with et containing 60 definitely affected individuals, using dinucleotide repeat ... | 1993 | 8341306 |
| effects of fetal genotype and uterine environment on placental development in equids. | measurement of the concentrations of equine chorionic gonadotrophin (ecg) in the serum of pregnant mares and jenny donkeys carrying normal intraspecies and hybrid interspecies pregnancies suggested that the production of this hormone may be influenced by parental gene imprinting. specifically, a differential expression of maternal and paternal genes may control the size and secretory activity of the structures that secrete ecg, the fetal endometrial cups. however, bisection of an interspecies mu ... | 1993 | 8345479 |
| african horse sickness. | ahs is a noncontagious vector-borne disease of equidae caused by orbiviruses. species susceptibility in decreasing order is horses, mules, donkeys, and zebras. the main vectors of ahs are culicoides. the disease is endemic in sub-saharan africa, but epizootics have occurred outside of this area on several occasions. the most recent outbreaks outside of the endemic area were in spain, morocco, and portugal between 1987 and 1990. ahs causes mortality up to 95% and is classically divided into four ... | 1993 | 8358648 |
| comparison of five tests for the serologic diagnosis of myiasis by gasterophilus spp. larvae (diptera: gasterophilidae) in horses and donkeys: a preliminary study. | sera from 41 horses and 159 donkeys, from twelve states of méxico, were tested to ascertain anti-gasterophilus circulating antibodies by double immunodiffusion (dd), counterimmunoelectrophoresis (cie), indirect haemagglutination (ih), thin layer immunoassay (tia) and diffusion-in-gel elisa (dig-elisa) methods using crude somatic antigen from third instar larvae of g. intestinalis (degeer). at necropsy, 33/41 horses and 24/159 donkeys were found to be parasitized by g. intestinalis and/or g. nasa ... | 1993 | 8369558 |
| wesselsbron virus haemagglutination: studies with erythrocytes of various animal species at different ph and temperatures. | the haemagglutinating (ha) properties of the nigerian strain of wesselsbron virus have been investigated using erythrocytes from a wide range of animals. the results showed that wesselsbron virus possesses ha activity when extracted using the sucrose and acetone method. the erythrocytes of goose, horse, donkey, pig, cattle, sheep, goat, monkey, man, rabbit, rat, guinea pig and chicken were agglutinated by wesselsbron virus at different ph values (5.75-7.0) and temperatures of 4 degrees c, room ( ... | 1993 | 8380321 |
| group-reactive elisas for detecting antibodies to african horsesickness and equine encephalosis viruses in horse, donkey, and zebra sera. | group-reactive enzyme-linked immunosorbent assays (elisas) were developed to selectively detect antibodies to african horsesickness virus (ahsv) and equine encephalosis virus (eev), 2 orbiviruses that infect equids. in indirect elisa, guinea pig antisera to all known ahsv or eev serotypes recognized immobilized ahsv serotype 3 or eev cascara, respectively. antisera from naturally infected animals did not cross-react with their respective heterologous viruses. the elisa was used in parallel with ... | 1993 | 8385502 |
| characterization of serum lysosomal enzymatic activities. iii. effect of infectious influenza in egyptian equines. | an outbreak of infectious influenza was recognized in menofeia governorate in october 1989. eight naturally influenza infected as well as 8 healthy control horses, mules and donkeys were selected for collection of blood and sera separation to estimate four lysosomal enzymatic activities and to describe the clinical findings, which were fever, congested nasal, conjunctival membranes and cough. bronchopneumonia followed later with bilateral purulent nasal discharge as a complication in 2 donkeys. ... | 1993 | 8387424 |
| [the role of the inositol phosphate cycle in the cardioprotective effect of adaptation to repeated stressors]. | as shown by previous studies, adaptation to short-term stress exposure developed the phenomenon of adaptive stabilization of structures (phass), including such as elevation in resistance to impairing effects of isolated animal hearts and the heart nuclear fraction of elements of the sarcoplasmic reticulum. studies of the role of inositol phosphate regulatory cycle in the development of the ass phenomenon showed that the inositol triphosphate-diacyl glycerol (itp-dag) step of regulation was activ ... | 1993 | 8390126 |
| serological evidence of equine arteritis virus in donkeys in south africa. | this paper reports the first serological evidence of exposure of donkeys to equine arteritis virus. seven hundred and thirty-four serum samples collected between 1989 and 1992 from donkeys in different areas of south africa were examined for the presence of antibodies against this virus by a microneutralization test. seventeen percent of serum samples tested positive. the distribution of seropositive animals varied from none in the western cape province and the transvaal highveld to 30% in the n ... | 1993 | 8392682 |
| dna of bovine papillomavirus type 1 and 2 in equine sarcoids: pcr detection and direct sequencing. | nucleotide sequences of bovine papillomavirus (bpv) dna amplified by the polymerase chain reaction (pcr) from samples of equine sarcoid skin tumours were determined. all naturally occurring sarcoids (n = 58 tumours from 32 horses and 2 donkeys) contained bpv-dna. all but 3 of the genome fragments belonged to the bpv type 1 strain (bpv-1); the remaining were bpv type 2. similar results were obtained with cutaneous bovine papillomas used as controls (n = 20). one of the horses, carrying 2 sarcoids ... | 1993 | 8394687 |
| algorithms for detecting antibodies to hiv-1: results from a rural ugandan cohort. | to evaluate an algorithm using two enzyme immunoassays (eia) for anti-hiv-1 antibodies in a rural african population and to assess alternative simplified algorithms. | 1993 | 8397940 |
| molecular evidence that epizootic venezuelan equine encephalitis (vee) i-ab viruses are not evolutionary derivatives of enzootic vee subtype i-e or ii viruses. | enzootic strains of venezuelan equine encephalitis (vee) virus occur in the united states (florida), mexico, central america and south america. epizootic vee first occurred in north and central america in a widespread outbreak between 1969 and 1972. to investigate the likelihood that this epizootic vee virus, identified as vee antigenic subtype i-ab, evolved from enzootic viruses extant in the region, we cloned and sequenced the 26s mrna region of the genomes of the florida vee subtype ii virus, ... | 1993 | 8445371 |
| physical mapping within the tuberous sclerosis linkage group in region 9q32-q34. | pulsed-field gel electrophoresis and flow dot-blot analysis have been used to construct a physical map of the q32-q34 region of chromosome 9, where one of the loci responsible for tuberous sclerosis (tsc1) has been mapped by genetic linkage. five linked groups of markers have been defined by pulsed-field gel electrophoresis. the orientation of these groups and the order of markers within them were determined by hybridization to flow-sorted dot blots derived from a panel of cell lines of chromoso ... | 1993 | 8449490 |
| [domestic animals and veterinary medicine in the old and new testaments of the bible and the apocrypha]. | referring to an 1865 edition of the bible, the article deals with domestic animals and veterinary matters in the sacred book of christianity, singling out donkey, camel, horse, sheep, goat, pig, dog and cat. comments on early aspects of animal welfare and food hygiene round off the picture. | 1993 | 8457188 |
| ultrastructure of epididymal epithelium in equus caballus. | the ultrastructure of the epithelial lining of the ductuli efferents and the ductus epididymis in the horse (equus caballus) is described. several types of cells can be distinguished: ciliated and non-ciliated cells make up the epithelium of the ductuli efferents, whereas principal, apical and basal cells are found in the ductus epididymis. the observations are compared with those made in other species, in particular in the donkey (equus asinus), and the possible functional roles of the differen ... | 1993 | 8465967 |
| interaction of a trypsin-like enzyme of porphyromonas gingivalis w83 with antithrombin iii. | we have previously observed that trypsin-like activity in porphyromonas gingivalis culture supernatants is inhibitable by the plasma arg-serpin antithrombin iii (atiii). this report demonstrates that a partially purified p. gingivalis trypsin-like enzyme (m(r) 47,000) is inhibited by atiii with an association rate constant (k(ass)) of 5.65 x 10(4) m-1 s-1 but does not form sds-stable complexes. heparin enhances the k(ass) and stabilizes the complexes but in either case such inhibition is tempora ... | 1993 | 8486244 |
| analysis of four microsatellite markers on the long arm of chromosome 9 by meiotic recombination in flow-sorted single sperm. | meiotic recombination in flow-sorted single sperm was used to analyze four highly polymorphic microsatellite markers on the long arm of chromosome 9. the microsatellites comprised three tightly linked markers: 9cmp1 (d9s109), 9cmp2 (d9s127), and d9s53, which map to 9q31, and a reference marker, ass, which is located in 9q34.1. haplotypes of single sperm were assessed by using pcr in a single-step multiplex reaction to amplify each locus. recombinant haplotypes were identified by their relative i ... | 1993 | 8503451 |
| implantation of a programmable atrioventricular pacemaker in a donkey with complete atrioventricular block and syncope. | 1993 | 8508758 | |
| linkage analysis in british and french families with idiopathic torsion dystonia. | idiopathic torsion dystonia is most commonly caused by an autosomal dominant gene or genes with reduced penetrance. an idiopathic torsion dystonia locus has been mapped to chromosome 9q34 in one large non-jewish and several jewish kindreds in the usa. linkage analysis was performed in 27 (26 british, one french) small families with idiopathic torsion dystonia, three of which were ashkenazi jewish, using the highly polymorphic loci argininosuccinate synthetase (ass) and abelson oncogene (abl) whi ... | 1993 | 8513401 |
| indirect immunofluorescence in the investigation of rapidly progressive sensorineural hearing loss and menière's disease. | being aware of the conservation of antigenicity, we performed indirect immunofluorescence on non fixed non decalcified frozen hamster's cochlea. once killed, the heads of the hamsters were immediately dipped into liquid nitrogen and then stored at -20 degrees c until cutting. the sections were done at the same temperature, with tissue-tek embedding the heads to avoid breaking, using a sharp tungsten knife. the immunofluorescence itself was performed with the sera of the patients which were revea ... | 1993 | 8517134 |
| purified yeast aspartic protease 3 cleaves anglerfish pro-somatostatin i and ii at di- and monobasic sites to generate somatostatin-14 and -28. | anglerfish somatostatin-14 (ss-14) and somatostatin-28 (ass-28) are derived from pro-somatostatin i (apss-i) and pro-somatostatin ii (pss-ii), respectively. purified yeast aspartic protease 3 (yap3), was shown to cleave apss-i at the arg81-lys82 to yield ss-14 and lys-1ss-14. in contrast, yap3 cleaved apss-ii only at the monobasic residue, arg73 to yield ass-28. since the paired basic and monobasic sites are present in both precursors, the results indicate that the structure and conformation of ... | 1993 | 8104828 |
| effects of new somatostatin analogs on the cell proliferation of colonic crypts and colonic cancers in rats. | the antiproliferative activity of two new somatostatin (ss) analogs: ass-51 and ass-52 have been tested in this study. we assessed their ability to inhibit the dna synthesis in normal colon crypt cells and in the cells of chemically (dimethylhydrazine)-induced colon cancer in the rats. the incorporation of bromodeoxyuridine (brdu) into appropriate cell nuclei was used as an index of dna synthesis. it was found that: 1) only ass-51 significantly decreases the colon crypt cell proliferation in the ... | 1993 | 8105412 |
| a search for the primary abnormality in adult-onset type ii citrullinemia. | deficiency of argininosuccinate synthetase (ass) causes citrullinemia in human beings. type ii citrullinemia is found in most patients with adult-onset citrullinemia in japan, and ass deficiency is found specifically in the liver. previous studies have shown that the decrease of hepatic ass activity is caused by a decrease in enzyme protein with normal kinetic properties and that there were no apparent abnormalities in the amount, translational activity, and gross structure of hepatic ass mrna. ... | 1993 | 8105687 |
| haemagglutination-inhibiting antibodies against african horse sickness virus in domestic animals in nigeria. | a sero-epidemiological survey of african horse sickness (ahs) virus in 261 animals which included 96 camels, 81 horses, 80 dogs and 4 donkeys was carried out in nigeria. the animals had no history of vaccination against ahs. sera were tested by the haemagglutination-inhibition (hi) test for the presence of antibody against ahs virus. of these, 77 (95.1%) horse, 4 (100%) donkey, 10 (10.4%) camel and 28 (35%) dog sera samples tested were recorded as positive. the prevalence of antibody in samples ... | 1993 | 8111431 |
| morphology of adult white donkeys of asinara. | the phenotype of the asinara white donkey has the following somatic characteristics: white coat, pink skin and glabrous areas, straight profile, body not very rounded on account of relatively slight muscular development, large head, eyes with irises of a pink-blue colour, short thin neck, not very pronounced withers, straight, average length dorsolumbar region, prominent angular rump higher than the withers, short chest, wide hind quarters, well developed abdomen, short sturdy limbs, light-colou ... | 1993 | 8198800 |
| solvent extraction of 8-quinolinolato-iron(iii) with the aid of various phenols as hydrogen-bonding donors. | effect of various phenols (aroh) on the solvent extraction of iron(iii) with 8-quinolinol (hq) has been investigated. greatly enhanced extraction is found in the presence of aroh, e.g., the distribution ratio of iron(iii) with hq in carbon tetrachloride is increased 200,000-fold by 0.10m 3,5-dichlorophenol. from extraction equilibrium analysis, the enhanced extraction has been ascribed to the formation of association complexes of neutral iron(iii) 8-quinolinolate (feq(3)) with aroh as feq(3) . n ... | 1993 | 18965621 |
| genereviews | the urea cycle disorders (ucd) result from defects in the metabolism of waste nitrogen from the breakdown of protein and other nitrogen-containing molecules. severe deficiency or total absence of activity of any of the first four enzymes (cps1, otc, ass, asl) in the urea cycle or the cofactor producer (nags) results in the accumulation of ammonia and other precursor metabolites during the first few days of life. infants with a severe urea cycle disorder are normal at birth but rapidly develop ce ... | 1993 | 20301396 |
| genereviews | citrullinemia type i (ctln1) presents as a clinical spectrum that includes an acute neonatal form (the "classic" form), a milder late-onset form, a form without symptoms or hyperammonemia, and a form in which women have onset of severe symptoms during pregnancy or post partum. distinction between the clinical forms is based on clinical findings and is not clear-cut. infants with the acute neonatal form appear normal at birth. shortly thereafter, they develop hyperammonemia and become progressive ... | 1993 | 20301631 |
| microsatellite analysis of loss of heterozygosity on chromosomes 9q, 11p and 17p in medulloblastomas. | medulloblastoma (mb) is a primitive neuroectodermal tumour of the cerebellum whose pathogenesis is poorly understood. previous studies suggest a role for loci on chromosomes 11p and 17p in the pathogenesis of mb. evidence for another potential mb locus has recently emerged from studies on gorlin syndrome (gs), an autosomal dominant syndrome with multiple basal cell carcinomas, epithelial jaw cysts, and skeletal anomalies. since gs can be associated with mb, we examined sporadic (non-gs) cases of ... | 1994 | 8208343 |
| effect of increasing work rate on metabolic responses of the donkey (equus asinus). | oxygen consumption (vo2) and concentration of venous blood metabolites were measured in donkeys trained to run and to pull loads on a treadmill. vo2 in two donkeys running at maximal speed on a 9.8% slope was 110 +/- 2 ml.min-1.kg-1, approximately 22 times preexercise vo2. average heart rate at maximal vo2 (vo2max) was 223 +/- 2 beats/min, five times the preexercise heart rate. blood lactate increased 14-fold, and blood glucose did not change (p > 0.05). animals running up a 4% incline and incre ... | 1994 | 7836149 |
| hyperlipemia in 9 miniature horses and miniature donkeys. | the medical records from 9 consecutive miniature horses (n = 5) and miniature donkeys (n = 4) with hyperlipemia (serum triglyceride concentration > 500 mg/dl) were reviewed. in all cases, hyperlipemia was a secondary complication of a primary systemic disease including septicemia, colitis, parasitism, esophageal obstruction, gastric impaction and rupture, fecalith, and pituitary adenoma. therapy consisted of specific treatment for the primary disease, supportive care, and nutritional support. th ... | 1994 | 7837116 |
| dehydration and rehydration in donkeys: the role of the hind gut as a water reservoir. | body fluid distribution was measured in three donkeys, fully hydrated, following dehydration and after being rapidly rehydrated. in twenty other donkeys that were slaughtered to supply food for predators in a safari zoo, the water content in the different compartments of the gastrointestinal tract (git) was assessed. prior to being slaughtered, four of the animals were fully hydrated, four dehydrated and 12 dehydrated, rehydrated and then slaughtered and examined, four at 1, for at 3 and four at ... | 1994 | 8736073 |
| age related igg subclass concentrations in asthma. | the prevalence of igg subclass deficiency in asthma is still controversial. earlier studies often included patients receiving treatment with systemic steroids which can induce hypogammaglobulinaemia. concentrations of igg subclasses were studies in 200 children (aged 2-17 years) with asthma (mean asthma severity score (ass) 2, range 1-4) who had not received systemic steroids for at least six weeks before investigation, and in 226 healthy age matched controls. the mean concentrations of igg subc ... | 1994 | 8135559 |
| nasal resistance in obstructive sleep apnea. | acute increases in nasal resistance are known to induce upper airway occlusion in predisposed subjects. with the limited efficacy of nasal surgery alone in the treatment of obstructive sleep apnea (osa), the relevance of chronically increased nasal resistance in the pathophysiologic features of osa remains undetermined. | 1994 | 8162738 |
| epidemiological observations on sarcoids in a population of donkeys (equus asinus). | an epidemiological study of equine sarcoid in a population of 4126 donkeys showed that the peak incidence of the disease was 15.2 cases per 100 animal-years and occurred in animals in their fourth year of life. the crude incidence of the disease was 0.6 cases per 100 animal-years. the disease occurred most frequently in younger, male animals during their first five years in the population. the lesions were observed most commonly in the paragenital region. pre-entry quarantine procedures did not ... | 1994 | 8171807 |
| detection of borna disease virus rna in naturally infected animals by a nested polymerase chain reaction. | borna disease virus in naturally infected horses, a donkey and sheep was detected for the first time by amplification of viral rna using pcr. in contrast to a control group of healthy horses, brain tissue was positive by this assay in all animals with neurological symptoms. the use of a second round of pcr with nested primers following southern hybridization confirmed the specificity and increased the sensitivity of the test. comparison with conventional methods recommends this technique for mon ... | 1994 | 8188810 |
| generation of a mouse model for citrullinemia by targeted disruption of the argininosuccinate synthetase gene. | argininosuccinate synthetase (ass) is a urea cycle enzyme that forms argininosuccinate from citrulline and aspartate. mutations at the ass locus in man cause the inherited disease, citrullinemia. citrullinemia is inherited as an autosomal recessive trait and is characterized, biochemically, by elevated levels of blood citrulline and ammonia and often results in early neonatal death if untreated. we have used homologous recombination in embryonic stem cells to generate a line of mice having a tar ... | 1994 | 8197477 |
| frequency of trypanosomosis and gastrointestinal parasites in draught donkeys in the gambia in relation to animal husbandry. | prevalence of trypanosomosis, gastrointestinal strongyles and level of strongyle egg outputs were studied in relation to husbandry practices in the draught donkey population in the gambia. feeding regime, number of working hours per day and overnight penning practices of donkeys affected significantly (p < 0.05) the level of gastrointestinal strongyle egg output, but not (p > 0.05) trypanosomosis prevalence. dual trypanosome and gastrointestinal strongyle infection significantly reduced the pcv ... | 1994 | 7941024 |
| bodyweight changes in pregnant and lactating donkey mares and their foals. | 1994 | 7941264 | |
| blood protein polymorphisms in the donkey (equus asinus). | transferrin, albumin, 6-phosphogluconate dehydrogenase and vitamin d-binding protein polymorphisms were detected in 242 feral and domesticated australian donkeys by polyacrylamide gel electrophoresis, starch gel electrophoresis, autoradiography, immunoblotting with specific antisera and activity staining. all four tf and two alb variants were donkey specific while only one of the pgd variants was donkey specific. the two gc variants were electrophoretically identical to the equus caballus f and ... | 1994 | 7943978 |
| conformational transitions of duplex and triplex nucleic acid helices: thermodynamic analysis of effects of salt concentration on stability using preferential interaction coefficients. | for order-disorder transitions of double- and triple-stranded nucleic acid helices, the midpoint temperatures tm depend strongly on a +/-, the mean ionic activity of uniunivalent salt. experimental determinations of dtm/d ln a +/- and of the enthalpy change (delta h(o)) accompanying the transition in excess salt permit evaluation of delta gamma, the stoichiometrically weighted combination of preferential interaction coefficients, each of which reflects thermodynamic effects of interactions of sa ... | 1994 | 7948695 |
| characteristics of acupuncture meridians and acupoints in animals. | in recent years, an increasing number of studies has been conducted on the biophysical characteristics of the meridians and acupoints in humans and animals. the authors aim to further illustrate the objective existence and superficial locations of the meridians in various species of animals. twelve sheep, ten goats, thirteen pigs, eleven cats, eight rabbits and seven donkeys were used to measure low impedance lines (lils) and high percussion sound lines (hpsls) on the skin surface of the animals ... | 1994 | 7949363 |
| seasonal variation in the function of blood monocytes obtained from healthy nonsmokers, asymptomatic smokers, and smokers with chronic bronchitis. | the present study focused on two questions: what effects do cigarette smoking and chronic bronchitis have on the function of the precursors of alveolar macrophages, the blood monocytes? can seasonal variations affect the function of these cells? phagocytic activity (the proportion of yeast-ingesting cells and the mean number of yeast particles per ingesting cell) and metabolism of arachidonic acid [secretion of prostaglandin e2 (pge2) and leukotriene b4 (ltb4) in zymosan-stimulated cultures] wer ... | 1994 | 7954908 |
| recent advances in the preparation and storage of red cells. | the policy of blood collection for transfusion and the supply of fractionated plasma products differ between countries which has a strong impact on the choice of methods for rbc preparation and storage. separation into components and storage of red cells in ass are commonly used. new methods for improved preparation have been developed, allowing better standardization of the blood components. several new compositions of as have been described which improve quality with respect to oxygen affinity ... | 1994 | 7975501 |
| ultrastructure of the epithelium that lines the ductuli efferentes in domestic equidae, with particular reference to spermatophagy. | the epithelium that lines the ductuli efferentes in the horse, donkey and mule has been examined by electron microscopy. the epithelium consists of columnar ciliated and non-ciliated cells. lymphocytes and macrophages are also present, together with cells that are rich in lipofuscin. these 'lipofuscin-rich' cells are a peculiar feature of the excurrent ducts of equidae and are characterized by a large number of highly heterogeneous residual bodies. the general morphology of the epithelium and, i ... | 1994 | 7976167 |
| two loci for tuberous sclerosis: one on 9q34 and one on 16p13. | 32 families informative for the segregation of tuberous sclerosis (tsc) have been examined for genetic markers on chromosomes 9, 11, 12 and 16. in one large family there was clear evidence of linkage to markers on chromosome 16p13.3 (lodscore with d16s291 of 4.7 at theta = 0) but other families were too small to give individually convincing lodscores. combined results for all families gave positive results with abo/dbh on chromosome 9 (max lod 2.63) and with d16s291 on chromosome 16 (max lod 3.9 ... | 1994 | 7979156 |
| dystonia in ashkenazi jews: clinical characterization of a founder mutation. | a gene (dyt1) for idiopathic torsion dystonia maps to chromosome 9q34 in ashkenazi jewish families with early onset of symptoms. further, there is linkage disequilibrium between dyt1 and a particular haplotype of alleles at 9q34 loci in this population. this implies that a large proportion of early-onset idiopathic torsion dystonia in ashkenazi jews is due to a founder mutation in dyt1. to characterize the phenotypic range of this mutation, we studied 174 ashkenazi jewish individuals affected wi ... | 1994 | 7979224 |
| [characterization and quantification of dermatan sulfate from donkey skin]. | dermatan sulfate (ds), a recently known antithrombotic glycosaminoglycan, was isolated and purified from donkey skin. physiochemical characteristics of the glycan, including constituent analysis, electrophoretic behaviour, molecular mass, specific lyase degradations, ir and pmr spectra were described, using porcine skin-origin dermatan sulfate as a standard reference. contents of ds in donkey skin and its gelatinized preparations (ejiao) were also measured. results indicate that the presence of ... | 1994 | 7980859 |