Publications

temporal and structural features of infant calls in relation to caregiving behaviour in common marmosets, callithrix j. jacchus.	the role of infants in the communal rearing system of marmosets and tamarins has received little attention although their demands may not be complied by inadequate helpers. as acoustic signalling plays an important role in their social communication, it is expected to be an effective way for infants to signal their demand for care. as a first approach, this study focussed on the use and quality of 'tsik' calls given by infants of common marmosets (callithrix j. jacchus) in the context of caregiv ...	1996	24896080
survey of cryptosporidium and giardia spp. in a captive population of common marmosets.		1996	8699808
urinary steroid and gonadotropin excretion across the reproductive cycle in female wied's black tufted-ear marmosets (callithrix kuhli).	details of the endocrinology of reproduction in the genus callithrix are known only for the common marmoset, c. jacchus. this paper presents the patterns of urinary pregnandiol-3-glucuronide (pdg), urinary estrone conjugates (e1c), and gonadotropin excretion throughout the reproductive cycle of wied's black tufted-ear marmoset (c. kuhli) as determined via steroid conjugate enzyme immunoassays (eia) and gonadotropin radioimmunoassays (ria). postpartum ovulation occurred at 13.6 ± 1.2 days after p ...	1996	31918517
patterns of prenatal survival in the common marmoset (callithrix jacchus).	fifty common marmoset pregnancies were monitored using ultrasound. the objective was to ascertain if fetal mortality was related to litter size. prior to analysis we determined abortion rate and litter size were not influenced by repeated ultrasound. mortality was unrelated to litter size and occurred fairly late in gestation. all singletons born in this study began gestation as twins. it is hypothesized that marmosets may be able to adjust litter size late in pregnancy in response to proximate ...	1996	8740954
thalidomide derivatives and the immune system. 6. effects of two derivatives with no obvious teratogenic potency on the pattern of integrins and other surface receptors on blood cells of marmosets.	the two thalidomide (thd) derivatives beta-em12 and phthalimidophthalimide (phtpht), which exhibit no obvious teratogenicity, were tested for their ability to induce changes in the pattern of lymphocyte subpopulations, and especially changes in integrin receptors, in marmosets (callithrix jacchus). previously, thd and its highly teratogenic derivative alpha-em12 had been found to alter the expression of adhesion molecules, such as cd2 (lfa-2) or cd11a/cd18 (lfa-1). none of these typical effects ...	1996	8538370
the effects of cage size and complexity on the behaviour of captive common marmosets, callithrix jacchus jacchus.	conditions of captivity of primates used in biomedical research may have deleterious effects on the welfare of the animals and consequently on the reliability of the research. we investigated the effects of cage size and cage complexity, two fundamental characteristics of captive conditions, on the behaviour of the common marmoset (callithrix jacchus jacchus). we found an increase in the general level of activity and significant variation in the frequencies of specific behaviours with an increas ...	1996	8938618
the biobehavioral consequences of psychogenic stress in a small, social primate (callithrix jacchus jacchus).	the biobehavioral consequences of psychogenic stress were examined using neuroendocrine and ethological methods in a captive colony of common marmosets (callithrix jacchus jacchus). specifically, hypothalamic-pituitary-adrenal (hpa) axis reactivity was evaluated as a function of gender and social status in four consecutive social environments [(1) stable heterosexual pairs; (2) isolation; (3) unstable peer groups; and (4) stable peer groups], by measuring both basal plasma cortisol, adrenocortic ...	1996	8874833
expression of integrins in marmoset (callithrix jacchus) ovary during folliculogenesis.	integrins were localized immunohistochemically in marmoset ovaries (callithrix jacchus) of defined cycle stages. with monoclonal antibodies against beta 1, alpha 2, alpha 3, and alpha 6 integrin subunits, immunoreactivity was predominantly found in ovaries of the follicular phase. in the luteal phase, non-luteal cells, e.g. fibroblasts or endothelial cells expressed beta 1, alpha 2, or alpha 6 integrins. immunostaining for the beta 1 subunit was strongest in granulosa cells of all growing follic ...	1996	8760853
intraventricular infusion of basic fibroblast growth factor (bfgf) in the mptp-treated common marmoset.	basic fibroblast growth factor (bfgf) prevents damage to the nigrostriatal system in rodents. we now report the effects of bfgf administered by intraventricular infusion to adult common marmosets (callithrix jacchus) previously rendered parkinsonian by the administration of 1-methy-4-phenyl-1,2,3,6-tetrahydropyridine (mptp). infusion commenced 10 weeks after mptp treatment and the animals received bfgf in low (1.8 micrograms/l), medium (18 micrograms/l), or high (180 micrograms/l) doses over a 2 ...	1996	8807747
the digestive strategy of the common marmoset, callithrix jacchus.	digestive tract morphology and function were studied in the common marmoset (callithrix jacchus), a small (350 g) exudivore with a well-developed caecum. transit times (times of first appearance of the markers in the faeces following a pulse dose in the food) were similar for co-edta, which marks the fluid phase of the digesta, and cr-mordanted cell walls, which marked the large (600-1200 microns) particulate phase of the digesta. however, mean retention time (the average time taken for the mark ...	1996	8925425
monitoring and controlling reproduction in captive common marmosets on the basis of urinary oestrogen metabolites.	non-invasive methods for routine monitoring of reproductive states and reproduction control in large colonies of captive callithrix jacchus have been developed. immunoactive urinary oestrone-3-conjugates (e1c) were measured during non-conception cycles (n = 5) and pregnancy (n = 7). using plasma progesterone levels to time ovulation, ovulation was quantitatively estimated by a) calculating the first e1c rise and b) by establishing an e1c threshold. ovulation was thus defined as taking place 4 da ...	1996	8783179
c-cells of marmosets (callithrix jacchus).	the localization and fine structure of c-cells of the thyroid glands from 31 marmosets (callithrix jacchus) of different age groups (newborn to 11 years old) were investigated by electron microscopy and immunomorphology (apaap, calcitonin). calcitonin-positive cells were found concentrated in the middle third of the gland. their localization in the follicular wall or in the interstitial space could not clearly be demonstrated by light microscopy. in adult animals, they were always located within ...	1996	8638770
spontaneous lesions detected in the common cotton-eared marmosets (callithrix jacchus).	spontaneous lesions in the common cotton-eared marmosets (callithrix jacchus), which were maintained in our laboratory or were purchased from a commercial breeder, were examined histopathologically. there were 39 males and 22 females, between the ages of 7 and 100 months. the most interesting finding noted was extramedullary hematopoiesis, which was observed in the mesenteric lymph nodes, spleen, liver, kidney, adrenal gland, and cerebral choroid plexus. megakaryocytes were frequently observed i ...	1996	8777223
an appraisal of the antiparkinsonian activity of piribedil in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated common marmosets.	the d2 dopamine agonist piribedil is not widely used in the treatment of parkinson's disease because it was thought to be effective mainly on parkinsonian tremor and to produce a high incidence of peripheral side effects, particular nausea. in this study, we used 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-treated primates to reevaluate the antiparkinsonian ability of piribedil after its oral administration in the presence or absence of domperidone pretreatment. adult common marmosets (c ...	1996	8684381
dopamine d3 receptors in the basal ganglia of the common marmoset and following mptp and l-dopa treatment.	the distribution of the dopamine d3 receptor was studied by receptor autoradiography using [3h]7-oh-dpat in striatal and extrastriatal brain regions of the common marmoset (callithrix jacchus). saturation studies demonstrated that [3h]7-oh-dpat bound with similar affinity to different regions of marmoset brain. in normal marmosets, specific [3h]7-oh-dpat binding was found in both striatal and extrastriatal regions. very high levels of specific [3h]7-oh-dpat binding were detected in the islands o ...	1996	8833762
occurrence of an infanticide within a captive polygynous group of common marmosets, callithrix jacchus.		1996	8990517
metabolism of reproductive steroids during the ovarian cycle in two species of callitrichids, saguinus oedipus and callithrix jacchus, and estimation of the ovulatory period from fecal steroids.	gonadal steroids were measured in daily fecal samples providing comparative data on steroid metabolism in two genera of new world primates. circulating bioactive lh and progesterone concentrations and fecal progesterone, pregnanediol, estradiol, and estrone concentrations were measured by collecting blood and daily fecal samples from four captive common marmoset females and four cotton-top tamarin females for 30 days. high recoveries (> 80%) of labeled steroids that were added directly to the fe ...	1996	8838005
sequences of the primate epsilon-globin gene: implications for systematics of the marmosets and other new world primates.	sequences of the epsilon-globin gene were determined for five species of marmosets, along with approximately 2 kb of 5' flanking sequence. an analysis of these data, compared with those of other primates strongly supports the classification of callithrix jacchus and c. geoffroyi into the jacchus group, and c. argentata and c. mauesi into the argentata group. the pygmy marmoset, formerly identified as cebuella pygmaea joined strongly to the argentata group, indicating that without the pygmy marmo ...	1997	9461380
ultrasonographic and hormonal monitoring of pregnancy in the saddle back tamarin, saguinus fuscicollis.	ultrasonography was used in six saddle back tamarin females (saguinus fuscicollis) to diagnose pregnancy, monitor the patterns of uterine growth and embryonic/foetal development and examine the incidence loss of single embryos/foetuses. pregnancy was reliably diagnosed 17 days after conception, 10 days earlier than by plasma progesterone measurement. the patterns of uterine and embryonic/foetal growth paralleled those reported for the common marmoset, including a delay in embryonic development. ...	1997	9438223
the common marmoset (callithrix jacchus) as a model for neuroleptic-induced acute dystonia.	to examine whether acute dystonia is induced by neuroleptic treatment, common marmosets were treated with haloperidol orally twice a week over 25 weeks until dystonic behavior was elicited. movement disorders such as acute dystonia were observed 6 weeks after the initial treatment, and had appeared in all treated animals by 25 weeks. once these movement disorders were induced, they consistently reappeared after further treatment with haloperidol, and once haloperidol dosing was discontinued, the ...	1997	9408199
marmoset conspecific confrontation: an ethologically-based model of anxiety.	a method of measuring confrontation-induced behavioural changes in common marmosets (callithrix jacchus) together with automated monitoring of locomotor activity has been developed as a possible model of anxiety. recording both affiliative and agonistic behaviours between male/female pairs of marmosets and using diazepam as a reference drug, it has been possible to define a profile of behavioural changes which could be regarded as representing an anxiolytic response. unfamiliar male/female pairs ...	1997	9264075
receptive field dimensions of lateral geniculate cells in the common marmoset (callithrix jacchus).	we measured the spatial receptive field dimensions of cells in the lateral geniculate nucleus (lgn) of the common marmoset (callithrix jacchus) using a bipartite field stimulus in which the two halves of the field were modulated identically but in counterphase. horizontal and vertical edges between the two fields were positioned at different locations in the receptive field. by assuming that centers and surrounds have gaussian profiles, we were able to obtain a satisfactory mathematical descript ...	1997	9578900
effects of click intensity and frequency on the brain-stem auditory evoked potentials in the common marmoset (callithrix jacchus).	brain-stem auditory evoked potentials (baeps) were recorded in 20 common marmosets (callithrix jacchus) to investigate the effects of click frequency up to 99 khz, in consideration of the higher hearing range of the marmoset, and intensity on wave forms and peak latencies. according to the results of baep recordings at frequencies of 4, 32, and 99 khz, the number of components recorded was affected by the stimulus intensity and the clicks at an intensity of 80 db peak equivalent sound pressure l ...	1997	9271451
spontaneous herpes simplex virus infection in common marmosets (callithrix jacchus).		1997	9249183
idiopathic myelofibrosis (agnogenic myeloid metaplasia) in a marmoset (callithrix jacchus): hematologic and histopathologic changes.	idiopathic myelofibrosis (imf), or agnogenic myeloid metaplasia, was diagnosed in a sexually mature male marmoset (callithrix jacchus) based on the results of hematology and histopathologic evaluation of the bone marrow. the hematologic changes included pancytopenia, leukoerythroblastosis, anisocytosis, poikilocytosis, and giant platelets. histopathologic evaluation of the bone marrow showed marked widespread fibrosis replacing hematopoietic cells and the presence of atypical megakaryocytes. in ...	1997	9240843
nitric oxide synthase inhibition and mptp-induced toxicity in the common marmoset.	nitric oxide, produced following activation of n-methyl-d-aspartate (nmda) receptors, may be involved in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) toxicity since nmda receptor antagonists have been shown to prevent mptp induced nigral cell loss in primates. common marmosets were treated with either saline or mptp or l-ngnitro arginine methyl ester (l-name) or mptp and l-name. mptp-treated common marmosets showed motor deficits including bradykinesia, rigidity, and tremor accompanied by ...	1997	9183819
the expression of sf-1/ad4bp is related to the process of luteinization in the marmoset (callithrix jacchus) ovary.	expression of the nuclear receptor, steroidogenic factor-1 (sf-1/ad4bp), was studied in a primate (marmoset) ovary using immunohistochemical, rt-pcr, and immunoblot techniques. the periovulatory phase was compared with the luteal phase. with pcr we found a marmoset homolog of sf-1/ad4bp to be expressed in ovarian and other steroidogenic tissues. characteristically, the periovulatory ovaries consisted of growing (non-luteinized) small follicles together with large luteinizing follicles and many c ...	1997	9151117
hepatic hemosiderosis in common marmosets, callithrix jacchus: effect of diet on incidence and severity.	we examined the effect of dietary iron concentration on the incidence of hepatic hemosiderosis in common marmosets (callithrix jacchus) and assessed the impact of hemosiderosis on animal health. thirteen young adult common marmosets were fed nutritionally balanced natural-ingredient diets formulated to contain either 100 or 500 ppm of iron. six were fed the low-iron and seven received the high-iron diet. baseline blood values and liver iron content were determined for each animal. animals were w ...	1997	9150491
competition and chemical communication in wild groups of common marmosets (callithrix jacchus).		1997	9071391
diagnosis and treatment of trichospirura leptostoma infection in common marmosets (callithrix jacchus).	trichospirura leptostoma is a spirurid nematode that inhabits the pancreatic ducts of the common marmoset, callithrix jacchus, and other new world primates. this parasite was diagnosed in members of this species at the marmoset research center in oak ridge, tennessee colony after their importation from multiple colonies outside the united states. animals with few parasites in the pancreas had few tissue changes, whereas those with many parasites had moderate to severe fibrosis replacing exocrine ...	1997	12456185
social context affects phee call production by nonreproductive common marmosets (callithrix jacchus).	common marmosets produce two variants of their long call (phee call) in different situations. intergroup calls are produced in territorial situations, and intragroup separation calls are produced by marmosets isolated from group members. marmoset groups frequently include postpubertal, nonreproductive members; their roles in the spontaneous production of territorial vocalizations is unclear. this study analyzed the production of home cage phee calls by nonreproductive, postpubertal marmosets whi ...	1997	9327096
interactions between infant growth and survival: evidence for selection on age-specific body weight in captive common marmosets (callithrix jacchus).	the objective of this study is to investigate factors influencing infant survival in captive common marmosets. we investigated the influence of age-specific weight, litter size, caging, and the presence of helpers on survival to 6 months of age in 189 callithrix jacchus infants. infant survival was analyzed using cox proportional hazards regression, and fitness functions were plotted to explore the relationship between survival and growth. results indicate that weights at birth and 120 days sign ...	1997	9261508
calbindin immunoreactivity delineates the circadian visual centers of the brain of the common marmoset (callithrix jacchus).	the hypothalamic suprachiasmatic nucleus and the thalamic pregeniculate nucleus (which includes the intergeniculate leaflet) comprise the circadian visual system in the primate brain. in this study, we used intraocular injections of cholera toxin subunit b to identify those nuclei in the common marmoset brain, and demonstrated that calbindin d-28k immunoreactivity apparently labels most neurons in both the suprachiasmatic and pregeniculate nuclei. these data suggest that calbindin d-28k could re ...	1997	9241439
the distribution of p75 neurotrophin receptor-immunoreactive cells in the forebrain of the common marmoset (callithrix jacchus).	the distribution of neurones that could be stained immunohistochemically with antibody to the p75 neurotrophin protein was studied in the forebrain of the common marmoset. the p75-immunoreactive forebrain cells appear to correspond to choline acetyltransferase-immunoreactive (i.e., cholinergic) neurones. two populations of cells could be distinguished on the basis of the intensity of p75 immunostaining. moderately stained cells correspond to cholinergic interneurones of the caudate and putamen, ...	1997	9222533
brain-stem auditory evoked potentials in the common marmoset (callithrix jacchus).	brain-stem auditory evoked potentials (baeps) were recorded in 10 common marmosets (callithrix jacchus) to investigate the effects of recording electrode configurations, stimulus rate, and stimulus frequency on baep wave forms and peak latencies. tone burst stimulations were used to evaluate the effects of pure tone on baep wave forms. five positive peaks superimposed on positive and negative slow potentials were identified in the baep recorded at the linkage between the vertex and the dorsal ba ...	1997	9076252
comparative study on age-dependent development of surface receptors on peripheral blood lymphocytes in children and young nonhuman primates (marmosets).	general conformity was found concerning age-dependent changes in the major subsets (cd4, cd8, cd2, cd20) and the adhesion molecules cd11a and cd29 on peripheral blood lymphocytes in children and young marmosets (callithrix jacchus). differences exist in the expression of the surface receptors cd45ra and cd56. taking the total number of white blood cells into account, an age-related increase in the absolute numbers of peripheral blood lymphocytes was found in marmosets whereas in children, an age ...	1997	9064482
familial influences on ovulatory function in common marmosets (callithrix jacchus).	previous studies have indicated that many, but not all, female common marmosets (callithrix jacchus) housed with their natal families undergo social suppression of ovulation. in this study, we further characterized ovulatory activity in common marmoset daughters to determine the prevalence of social suppression of ovulation and to elucidate familial influences on daughters' ovarian activity. blood samples were collected twice weekly from each of 46 daughters for 5-12 months, usually beginning wh ...	1997	9057963
location and developmental regulation of androgen receptor in primate ovary.	locally produced androgens act via granulosa cell androgen receptors to modulate follicular responsiveness to gonadotrophins and thereby contribute to the paracrine regulation of ovarian function. we used quantitative androgen receptor immunocytochemistry to assess androgen receptor distribution in relation to pre-ovulatory follicular development in the common marmoset (callithrix jacchus), a new world primate that ovulates two to four follicles in each approximately 28 day ovarian cycle. ovarie ...	1997	9043913
cardiac-like musculature of the intrapulmonary venous wall of the long-clawed shrew (sorex unguiculatus), common tree shrew (tupaia glis) and common marmoset (callithrix jacchus).	the cardiac-like musculature is distributed not only in the heart wall but also in the intrapulmonary venous wall in a few species of insectivores. it has been suggested that the evolutionary origin of venous cardiac-like musculature may be traceable to a basic stock of certain mammalian lines of descent. so, it is important to clarify whether the musculature may be a common structure in lower mammals from insectivores to primates and to examine the functional significance of the structure.	1997	8986302
casa as an aid to selecting sperm suspensions for artificial insemination in callithrix jacchus.	the ability to use sperm motility parameters, obtained by computer-assisted sperm motility analysis (casa), as an aid to selecting sperm samples for artificial insemination (ai) would have considerable benefits for commercial organizations and for the captive breeding of endangered species. in this study the hobson sperm tracker (hst) was validated for use with spermatozoa from callithrix jacchus, the common marmoset, by comparing values for straight line velocity by casa with those obtained by ...	1997	16130273
entacapone enhances levodopa-induced reversal of motor disability in mptp-treated common marmosets.	oral administration of levodopa (l-dopa) (2.5-25.0 mg/kg) plus carbidopa (12.5 mg/kg p.o.) to mptp-treated common marmosets produced a dose-related increase in locomotor activity and a corresponding decrease in motor disability. pretreatment with the peripheral comt inhibitor entacapone (12.5 mg/kg p.o.) enhanced the intensity and duration of the increase in locomotor activity and the reversal of motor disability produced by a threshold dose of l-dopa (2.5 mg/kg p.o.) plus carbidopa. by contrast ...	1997	9399218
escape from social suppression of sexual behavior and of ovulation in female common marmosets.		1997	9071400
behavioral and social correlates of escape from suppression of ovulation in female common marmosets housed with the natal family.	although female common marmosets typically do not breed while housed with their natal families, up to half ovulate at least once while housed with the intact natal family, and a similar proportion conceive if an unrelated adult male is present in the group. in this study, we investigated the behavioral and social correlates of escape from suppression of ovulation by daughters housed in intact natal families or in families in which the father had been replaced by an unrelated adult male. focal-an ...	1997	9064194
local relaxin biosynthesis in the ovary and uterus through the oestrous cycle and early pregnancy in the female marmoset monkey (callithrix jacchus).	the pattern of peripheral serum concentration for the peptide hormone relaxin in women points to the possibility of an interesting paracrine function in the cycle and early pregnancy. in order to investigate this physiology in detail, it was decided to examine local relaxin biosynthesis in an established primate model for human female reproductive function, the marmoset monkey (callithrix jacchus). in this initial study relaxin biosynthesis was assessed using a combination of molecular and immun ...	1997	9222026
evidence that blue-on cells are part of the third geniculocortical pathway in primates.	colour vision in primates is mediated by cone opponent ganglion cells in the retina, whose axons project to the dorsal lateral geniculate nucleus in the visual thalamus. it has long been assumed that cone opponent ganglion cells project to the parvocellular layers of the geniculate. here, we examine the role of a third subdivision of the geniculocortical pathway: the interlaminar or koniocellular geniculate relay cells. we made extracellular recordings in the dorsal lateral geniculate nucleus of ...	1997	9240412
number of ovulations in the marmoset monkey (callithrix jacchus): relation to body weight, age and repeatability.	the relation between number of ovulations and body weight, age or maternal identity was examined in 69 ovarian cycles from 29 captive-born common marmoset monkeys (callithrix jacchus). specifically, we addressed the following questions: was there high repeatability of ovulation number? most of the variation in ovulation number was within, rather than between subjects. repeatability in number of ovulations was 0.081 (n = 20 females with 2-6 ovulatory cycles per female); was age related to number ...	1997	9261513
(-)-osu 6162 inhibits levodopa-induced dyskinesias in a monkey model of parkinson's disease.	we have studied the effects of two d2 dopamine receptor-selective compounds, (-)-osu 6162 and raclopride, on levodopa-induced dyskinesias in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-lesioned common marmosets (callithrix jacchus). three monkeys developed a severe parkinsonian syndrome following administration of mptp. in response to daily levodopa treatment the animals developed reproducible and idiosyncratic peak-dose dyskinesias. pretreatment with (-)-osu 6162 and raclopride, in dose ...	1997	9261828
vasopressin and oxytocin immunoreactive neurons and fibers in the forebrain of male and female common marmosets (callithrix jacchus).	vasopressin (avp) and oxytocin (ot) immunoreactive (ir) neurons and fibers were examined in the forebrain of male and female common marmosets (callithrix jacchus). as expected from previous studies of cell distribution in the rodent and primate brain, avp-ir cells were most evident in the paraventricularis, supraopticus, and suprachiasmaticus of the hypothalamus. avp-ir cells were also widely distributed in the lateral hypothalamus and the bed nucleus of the stria terminalis. a sexually dimorphi ...	1997	9268061
n-methyl-d-aspartate subunit r1 involvement in the postnatal organization of the primary visual cortex of callithrix jacchus.	it has been demonstrated that the primary visual cortex is highly sensitive to manipulations of the visual environment during a specific, early, postdevelopmental period: the critical period. pharmacological studies have shown that n-methyl-d-aspartate (nmda) receptors are involved in the plasticity of the visual cortex just as they are involved in the induction of long-term potentiation (ltp), another activity-dependent form of plasticity. the setting up of synaptic connectivity in the neocorte ...	1997	9295151
learning impairments following injection of a selective cholinergic immunotoxin, me20.4 igg-saporin, into the basal nucleus of meynert in monkeys.	four groups of monkeys (callithrix jacchus) were injected with saline or increasing amounts of the immunotoxin, me20.4 igg-saporin, directly into the basal nucleus of meynert via a frontal trajectory which avoided damage to the overlying basal ganglia. me20.4 igg binds to the primate p75 low-affinity neurotrophin receptor, when the saporin derivitized antibody is injected into the basal forebrain, it selectively destroys the magnocellular neurons of the basal nucleus of meynert which are the cel ...	1997	9300425
four-week repeated inhalation study of hcfc 225ca and hcfc 225cb in the common marmoset.	four male and three female marmosets in each group were exposed to air only, 1000 ppm of hcfc 225ca or 5000 ppm of hcfc 225cb, for 6 h per day for 28 consecutive days. hcfc 225ca caused a slight reduction in body weight. hcfc 225cb occasionally caused somnolence during exposure and vomiting on the first day of exposure. clinical chemistry findings included a mild reduction of triglyceride, cholesterol and phospholipid levels and increased got level in the hcfc 225ca exposure group. hcfc 225cb al ...	1997	9334832
proliferation and apoptosis in follicles of the marmoset monkey (callithrix jacchus) ovary.	proliferation and apoptosis were studied in ovarian follicles of immature and pubertal marmosets and in mature marmosets during the follicular, periovulatory and luteal phases. proliferation was evaluated using a ki 67 antibody and apoptosis was assessed by in situ detection of dna fragmentation. in the immature animals only small follicles were present, and the expression of ki 67 was restricted to the granulosa cells of follicles localised near the medulla. there was no evidence of dna fragmen ...	1997	9341948
report on primate supply for biomedical scientific work in the uk. eupren uk working party.	a working party of the uk group of european primate resources network (eupren) considered primate supply for scientific work in the uk. through a questionnaire, which achieved a very good response, it obtained details of primate use, sources and breeding in the uk and it put forward options to ensure that animal welfare is the best possible whilst ensuring continued supply. the questionnaire showed that contract research laboratories and pharmaceutical companies use about 80% of the 4233 primate ...	1997	9350698
relationship between expression of integrins and granulosa cell apoptosis in ovarian follicles of the marmoset (callithrix jacchus).	dna fragmentation (apoptosis) was studied during the follicular, periovulatory and luteal phase in the marmoset monkey ovary by means of terminal transferase mediated in situ nick end labeling, and correlated with immunohistochemical localization of integrins (beta 1, alpha 2 and alpha 6 subunits). for this purpose a double-labeling technique was developed. during all phases, apoptosis of granulosa cells was exclusively restricted to tertiary follicles displaying advanced stages of atresia (as m ...	1997	9364802
increased dopamine turnover in the putamen after mptp treatment in common marmosets.	the differences in dopamine turnover rate between the putamen and the caudate nucleus in the striatum lesioned by a neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) were studied in the common marmoset, a small new world monkey. systemic administration of mptp damaged equally and dose-dependently nigrostriatal dopaminergic neurons projecting both to the caudate nucleus and the putamen. the compensatory increase of dopamine turnover, however, occurred more prominently in the putamen ...	1997	9367253
vasopressin in the forebrain of common marmosets (callithrix jacchus): studies with in situ hybridization, immunocytochemistry and receptor autoradiography.	the distribution of vasopressin (avp) producing cells, their projections and avp receptors was examined in the brain of common marmosets (callithrix jacchus) using in situ hybridization, immunocytochemistry and receptor autoradiography. clusters of cells labeled for avp mrna or stained for avp immunoreactivity (avp-ir) were found in the paraventricular (pvn), supraoptic (son) and suprachiasmatic nuclei (scn) of the hypothalamus. scattered avp producing cells were also found in the lateral hypoth ...	1997	9369311
cell death during luteal regression in the marmoset monkey (callithrix jacchus).	the mechanism controlling luteal regression in primates is unknown but may involve cell death by apoptosis. marmoset ovaries containing corpora lutea were studied at different stages of the normal ovarian cycle. two additional groups of animals underwent induced luteolysis with either the prostaglandin f2 alpha analogue, cloprostenol, or the gnrh antagonist, antarelix, at the mid-luteal phase. apoptosis in ovarian sections was estimated both by counting the number of cells exhibiting morphologic ...	1997	9370974
reproductive efficiency in the common marmoset (callithrix jacchus): a longitudinal study from ovulation to birth monitored by ultrasonography.	this study examines reproductive efficiency in the common marmoset monkey, callithrix jacchus, using sequential ultrasound examinations to establish ovulation number, implantation rate, and incidence of prenatal loss. ultrasound was carried out with a 10 or 7.5 mhz probe in nonsedated animals, daily during the late follicular phase, approximately twice a week until day 20 after ovulation, and at days 35, 56, and 85 of pregnancy to enable visualization of gestation sacs, heartbeats, and fetal hea ...	1997	9379480
inhibition of allergic encephalomyelitis in marmosets by vaccination with recombinant vaccinia virus encoding for myelin basic protein.	a primary demyelinating form of experimental allergic encephalomyelitis (eae) resembling human multiple sclerosis (ms) occurs in callithrix jacchus marmosets following immunization with human white matter. participation of a t-cell immune response against myelin basic protein (mbp) in this disease model is supported by observations of increased reactivity against mbp in pbmc and of adoptive transfer of an inflammatory form of eae by mbp-reactive t-cells. to evaluate the effects of ectopic presen ...	1997	9394784
oxytocin and oxytocin receptor expression in reproductive tissues of the male marmoset monkey.	using a combination of reverse transcriptase polymerase chain reaction to detect specific mrna and immunohistochemistry employing antibodies that recognize two different epitopes for each molecule, the local production of oxytocin (ot) and its cognate receptor was investigated in the male marmoset monkey (callithrix jacchus). there was synthesis of both ot and the oxytocin receptor (otr) within the testis, and both were markedly expressed within the leydig cells. a weak staining for both ot and ...	1997	9116141
five new or recently discovered (gbv-a) virus species are indigenous to new world monkeys and may constitute a separate genus of the flaviviridae.	in previous studies, human hepatitis viruses have been experimentally transmitted to new world monkeys of the genus saguinus (tamarins). recently, two flaviviridae-like agents (gbv-a and gbv-b) were identified in tamarins that developed hepatitis following inoculation with serum of the 11th tamarin passage of a potentially new human hepatitis agent. however, it was not shown that these viruses originated from the initial inoculum. we here report the discovery of indigenous species-specific virus ...	1997	9126255
direct demonstration of persistent epstein-barr virus gene expression in peripheral blood of infected common marmosets and analysis of virus-infected tissues in vivo.	epstein-barr virus (ebv) infection in animal model systems has been studied previously in marmosets and tamarins using serology and pcr of saliva. here we directly demonstrated long-term persistence of ebv in the peripheral blood of marmosets by assaying eber rna expression. a new reverse transcription-pcr assay, able to distinguish a naturally occurring strain polymorphism in eber 2 that may be useful as a strain marker for monitoring persistence and interactions between multiple strains in the ...	1997	9191939
immunolocalisation of oestrogen receptor-alpha within the testis and excurrent ducts of the rat and marmoset monkey from perinatal life to adulthood.	the sites of action and the physiological role of oestrogens in the male reproductive tract are poorly understood. we have undertaken a systematic study of the immunoexpression of oestrogen receptor-alpha (er alpha) in the male rat from late fetal life through to adulthood and compared the findings with results obtained in the marmoset monkey (callithrix jacchus) from neonatal to adult life. the testes, rete testis, efferent ducts and epididymis were examined from normal male rats (aged 4, 8, 10 ...	1997	9204003
a local oxytocin system is part of the luteinization process in the preovulatory follicle of the marmoset monkey (callithrix jacchus).	luteinization is a complex differentiation process involving the interaction of extrinsic and intraovarian factors. the aim of this study was to examine the components of an intraovarian oxytocin (ot) system during the periovulatory period in the marmoset monkey, as well as the possible relationship of these components to other factors involved in the luteinization process, using immunohistochemistry and cell culture techniques. ovaries were collected on day 7 of the follicular phase (before the ...	1997	9209075
characterization of the tcrb chain repertoire in the new world monkey callithrix jacchus.	callithrix jacchus is an outbred new world primate characterized by a naturally occurring bone marrow chimerism, restricted polymorphism at many mhc loci, and unusual susceptibility to viral pathogens, adenocarcinoma, colitis, and, following immunization with myelin antigens, a demyelinating disease of the central nervous system closely resembling human multiple sclerosis. here we characterize the tcrb repertoire in this species, representing the first such analysis in a new world monkey. two tc ...	1997	9013960
age of epiphyseal closure in tamarins and marmosets.	estimates of the chronological age for animals of unknown age provide useful information for medical, demographic, and evolutionary studies. skeletal development, as indicated by epiphyseal closure, can be used to estimate an animal's chronological age or specify its stage of development. many studies of primate skeletal development have used animals of unknown age, with the order of epiphyseal closure providing a relative age for each animal. this study examines the age of epiphyseal closure at ...	1997	9050370
morphological analysis of the blue cone pathway in the retina of a new world monkey, the marmoset callithrix jacchus.	we have studied the components of the short wavelength-sensitive (sws or "blue") cone pathway in the retina of a new world primate, the marmoset callithrix jacchus. of particular interest was the small bistratified ganglion cell, which has been identified in macaque monkey to be the morphological substrate of the blue-on cell (dacey and lee [1994] nature 367:731-735). small bistratified cells were intracellularly filled with neurobiotin in an in vitro retinal wholemount preparation. their morpho ...	1997	9050786
the morphology and distribution of horizontal cells in the retina of a new world monkey, the marmoset callithrix jacchus: a comparison with macaque monkey.	the morphology and distribution of horizontal cells was studied in the retina of a new world monkey, the marmoset, callithrix jacchus, and compared with that of the old world macaque monkey. horizontal cells in macaque and marmoset were either labelled with the carbocyanine dye, dii, and then photoconverted, or were labelled by intracellular injection with neurobiotin. the marmoset has two types of horizontal cell, h1 and h2, which have dendritic and axonal morphology similar to their counterpar ...	1997	9057275
development of an enzyme-immunoassay (eia) for the measurement of follicle-stimulating-hormone (fsh) in callitrichid primates using a monoclonal antibody against the human-fsh-beta-subunit.	despite the importance of callitrichid primates in both biomedical and conservation research, practical and reliable immunoassays for the measurement of follicle-stimulating hormone (fsh) have not yet been described. a panel of monoclonal antibodies against specific peptide fragments within either the alpha or beta subunit of human fsh was evaluated for their ability to recognize fsh from callitrichid and other new world primates. one of these, monoclonal antibody 46.3h6.b7 raised against human ...	1997	9057964
birth of offspring following artificial insemination in the common marmoset, callithrix jacchus.	the objective of the study was to develop a method for artificial insemination (ai) in the common marmoset, a new world primate species. for ai to be successful, sperm must be deposited at an appropriate site and time in the female reproductive tract, details of which are currently not available for callitrichid species. epididymal sperm were deposited in the cervix of 18 marmoset monkeys (callithrix jacchus) around the time of expected ovulation using either 3, 2, or 1 inseminations. six out of ...	1997	9064196
comparative chromosomal study of five taxa of genus callithrix, group jacchus (platyrrhini, primates).	the karyotypes of four marmoset species of the callithrix jacchus group (c. aurita, c. kuhlii, c. geoffroyi, and c. penicillata) were investigated. the patterns of g-, c-, and nor-bands of these karyotypes were compared with those of c. jacchus, previously described, in order to clarify the taxonomic relationships of this species group. all species present 2n = 46, 14 uni- and 30 biarmed autosomes, a median size submetacentric x chromosome, and the same nor-band patterns. no rearrangement or con ...	1997	9064198
functional characterization and purification of an intracellular vitamin d-binding protein in vitamin d-resistant new world primate cells. amino acid sequence homology with proteins in the hsp-70 family.	most genera of new world primates exhibit resistance to vitamin d. these monkeys harbor high circulating concentrations of the prohormone 25-hydroxyvitamin d and the active vitamin d hormone 1, 25-dihydroxyvitamin d. previous work from this laboratory indicated that resistance is associated with the overexpression of a 60-65-kda intracellular protein that binds vitamin d metabolites competitively. in the current studies 25-[3h]hydroxyvitamin d3 (25-ohd3) was used as a competitive ligand to inves ...	1997	9079669
creation of a model for multiple sclerosis in callithrix jacchus marmosets.	multiple sclerosis (ms) is an inflammatory disease of the cns white matter characterized pathologically by the accumulation of perivascular and parenchymal t lymphocytes (t cells), and macrophage infiltration associated with myelin destruction. ms lesions are also characterized by the death of oligodendrocytes (the myelin-producing cells) and proliferation and hypertrophy of astrocytes with scar tissue (gliosis) replacing normal myelin. these changes result in the loss of axonal conduction for n ...	1997	9106075
toxoplasmosis in a colony of new world monkeys.	in a colony of new world monkeys five tamarins (saguinus oedipus, saguinus labiatus and leontopithecus rosal. rosal.), three marmosets (callithrix jacchus and callithrix pygmaea) and one saki (pithecia pithecia) died suddenly. the colony comprised 16 marmosets, 10 tamarins and three sakis. the main pathological findings were necrotic lesions in the lung, the intestine, and the liver. histopathologically t. gondii parasites were observed in organs from the tamarins and the marmosets but not in th ...	1997	9106950
fertilization-promoting peptide in reproductive tissues and semen of the male marmoset (callithrix jacchus).	fertilization-promoting peptide (fpp) is present in the prostate gland and semen of some mammals, and has been shown to enhance the fertilizing ability of both epididymal mouse and ejaculated human spermatozoa. the novel peptide may prove of importance for the treatment of some cases of male infertility, and a suitable animal model would be useful to test this hypothesis. to this end, we examined reproductive tissues and semen of the male marmoset for the presence of fpp. peptides were extracted ...	1997	9110322
igf-i variants which bind poorly to igf-binding proteins show more potent and prolonged hypoglycaemic action than native igf-i in pigs and marmoset monkeys.	the relative acute hypoglycaemic potencies of igf-i and several variants of igf-i which bind poorly to the igf-i binding proteins (igfbps) have been examined in marmosets (callithrix jacchus) and the pig. in the marmoset study, igf-i and des(1-3)igf-i were compared in anaesthetised and conscious animals in a range of bolus doses from 42 to 270 micrograms/kg body weight. in the pig study, igf-i was compared with four variants, des(1-3)igf-i long-igf-i, r3igf-i and long-r3igf-i (lr3igf-i), which s ...	1997	9415072
nonsurgical embryo transfer in the common marmoset monkey.	a technique for nonsurgical embryo transfer in common marmosets was developed. transfers were either synchronous (st) or asynchronous (at). synchronous transfers (embryo donor and the embryo recipient ovulated on the same day) were performed 5 to 8 days post-ovulation. asynchronous transfers (embryo donor had ovulated at least 2 days before the embryo recipient) were performed when the recipient was 2 to 4 days post-ovulation (donor was 6 to 8 days post-ovulation). four pregnancies from nine tra ...	1997	9437262
hand preference during behavioral tests and spontaneous activity in two species of common marmoset (callithrix jacchus and callithrix penicillata).	hand preference in two adult c. jacchus (one male and one female) and five c. penicillata (three adult females and two 70-day-old male and female infants) was examined in this study. animals were housed in large wire mesh cages and daily tested twice during 40 consecutive days in 15-minute experimental sessions. tests were carried out with dog food pellets and were as follows: 1) food taking from a glass cylinder (12 cm long x 5 cm diameter), 2) food taking from an opaque plastic flask (11 cm lo ...	1997	9440356
[experimental in vivo passage of h2 strain of live attenuated vaccine of hepatitis a in common marmosets].	common marmosets with negative serum antibodies against hepatitis a virus (anti-hav) and normal liver functions were used for the tests of passage of h2 vaccine strain of hav to explore its residual virulence after attenuation and possibility of its reversion. common marmosets were inoculated with attenuated live vaccine, and fecal suspension and/or proliferative liquid in tissue culture of the progeny of vaccine hav excreted from their feces were passaged in common marmosets. result of three se ...	1997	9812599
role of androgens in follicle maturation and atresia.	androgens are products of progestogen metabolism, intermediates in oestrogen biosynthesis and local regulators of ovarian function. current understanding of intraovarian androgen formation, metabolism and action is reviewed, highlighting the contribution of androgens to the paracrine regulation of follicular maturation and atresia. any factor that alters intracellular camp levels is a potential modulator of granulosa cell differentiation, and hence follicular development. androgen appears to mod ...	1997	9536210
lipid lowering effects of pravastatin in common marmosets.	in the present study it was examined if the common marmoset was susceptible to pravastatin (cas 81131-70-6, cs 514, mevalotin), an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a (hmg-coa) reductase. it has been reported that serum lipid levels in common marmosets resemble those in humans. first serum total cholesterol and lipoprotein cholesterol levels of common marmosets were examined in comparison with those in seven different experimental animals including cynomolgus monkeys, beagle dogs, ...	1998	9541726
adenosine a2a antagonist: a novel antiparkinsonian agent that does not provoke dyskinesia in parkinsonian monkeys.	treatment of parkinson's disease with l-dopa therapy leads to long-term complications, including loss of drug efficacy and the onset of dyskinesia. adenosine a2a receptors in striatum are selectively localized to gabaergic output neurons of the striato-pallidal pathway and may avoid such problems. the novel adenosine a2a receptor antagonist kw-6002 has been examined for antiparkinsonian activity in mptp-treated primates. oral administration of kw-6002 reversed motor disability in mptp-treated co ...	1998	9546333
deregulation of cell growth by the k1 gene of kaposi's sarcoma-associated herpesvirus.	at a position equivalent to the gene encoding the saimiri transforming protein (stp) of herpesvirus saimiri (hvs), kaposi's sarcoma-associated herpesvirus (kshv) contains a distinct open reading frame called k1. although kshv and hvs are related members of the rhadinovirus subgroup of gamma herpesviruses, k1 and stp exhibit no similarity in amino acid sequence or in structural organization. since stp is required for the oncogenic potential of hvs, we investigated the functional consequence of k1 ...	1998	9546789
visuotopic organisation and neuronal response selectivity for direction of motion in visual areas of the caudal temporal lobe of the marmoset monkey (callithrix jacchus): middle temporal area, middle temporal crescent, and surrounding cortex.	on the basis of extracellular recordings in marmoset monkeys, we report on the organisation of the middle temporal area (mt) and the surrounding middle temporal crescent (mtc). area mt is approximately 5-mm long and 2-mm wide, whereas the mtc forms a crescent-shaped band of cortex 1-mm wide. neurones in area mt form a first-order representation of the contralateral hemifield, whereas those in the mtc form a second-order representation with a field discontinuity near the horizontal meridian. the ...	1998	9550155
substitution of ras for the herpesvirus saimiri stp oncogene in lymphocyte transformation.	stp-c488 (stp of herpesvirus saimiri [hvs] group c strain 488 [c488]) is the only virus-encoded protein found to associate with cellular ras and activate ras signal transduction pathways. to investigate an important role for ras signal transduction in stp-dependent growth transformation, we constructed recombinant strains of hvs c488 in which the stp-c488 oncogene was replaced with cellular normal ras (c-ras) or viral oncogenic ras (v-ras). recombinant hvs deltastp/v-ras immortalized primary com ...	1998	9557651
insulin-like and fibroblast growth factors and their receptors are differentially expressed in the oviducts of the common marmoset monkey (callithrix jacchus) during the ovulatory cycle.	it is suggested that growth factors support the process of maturation and differentiation in the mammalian oviduct. fibroblast growth factors (fgf) and insulin-like growth factors (igf) are possible influences on these processes. the present study describes for the first time the expression of fgf-1 and -2 and their receptors as well as igf-1 and -2 and the corresponding igf receptor type 1 in the oviduct of the new world monkey callithrix jacchus. because of the limited rna yields from oviducts ...	1998	9623605
functional and adaptive significance of primate pads and claws: evidence from new world anthropoids.	this study tests predicted morphoclines in fingertip morphology among four small-bodied (<1 kg) new world monkeys (saimiri sciureus, leontopithecus rosalia, callithrix jacchus, and saguinus oedipus) in order to test previous functional and adaptive explanations for the evolution of flattened nails, expanded apical pads, and grasping extremities within the order primates. small-bodied platyrrhines which frequently forage among small-diameter substrates are expected to possess 1) relatively expand ...	1998	9637179
tularemia in a common marmoset (callithrix jacchus) diagnosed by 16s rrna sequencing.	we report a case of tularemia in a common marmoset (callithrix jacchus) diagnosed by determination of the isolate's 16s ribosomal rna (rrna) gene sequence. pathological examination of the animal revealed a multifocal acute necrotizing hepatitis, interstitial nephritis, splenitis, and lymphangitis of the mandibular, retropharyngeal, and cervical and mesenteric lymph nodes. moreover, multiple foci of acute necrosis were found in the epithelium of the jejunum and the interstitium of the lung. bacte ...	1998	9646473
expression of accessory molecules and cytokines in acute eae in marmoset monkeys (callithrix jacchus).	accessory molecules and cytokines are involved in the immunopathogenesis of multiple sclerosis (ms) and experimental autoimmune encephalomyelitis (eae) in rodent models, and are potential targets for immunotherapy. evaluation of such experimental therapies requires appropriate animal models. therefore, we analysed the expression of selected accessory molecules and cytokines in the brain of marmoset monkeys (callithrix jacchus) with acute eae, a newly described non-human primate model for ms. all ...	1998	9655470
a role for herpesvirus saimiri orf14 in transformation and persistent infection.	the product of open reading frame 14 (orf14) of herpesvirus saimiri (hvs) exhibits significant homology with mouse mammary tumor virus superantigen. orf14 encodes a 50-kda secreted glycoprotein, as shown previously (z. yao, e. maraskovsky, m. k. spriggs, j. i. cohen, r. j. armitage, and m. r. alderson, j. immunol. 156:3260-3266, 1996). orf14 expressed from recombinant baculovirus powerfully induces proliferation of cd4-positive cells originating from several different species. to study the role ...	1998	9658125
immunization of common marmosets with epstein-barr virus (ebv) envelope glycoprotein gp340: effect on viral shedding following ebv challenge.	epstein-barr virus (ebv), the cause of infectious mononucleosis, is involved in the pathogenesis of several human cancers, the highest frequency of association being found in undifferentiated nasopharyngeal carcinoma and endemic burkitt's lymphoma. the development of animal models in which potential vaccines can be tested is important. ebv infection of the common marmoset, using the m81 strain originally derived from a patient with nasopharyngeal carcinoma, induces a carrier state in this animal ...	1998	9661832
the distribution of calcium-binding proteins in the lateral geniculate nucleus and visual cortex of a new world monkey, the marmoset, callithrix jacchus.	antibodies directed against the calcium-binding proteins, parvalbumin and calbindin, can be used to label distinct neuronal subgroups in the primate visual pathway. we analyzed parvalbumin immunoreactivity (p-ir) and calbindin immunoreactivity (c-ir) in the lateral geniculate nucleus (lgn) and visual cortex of the marmoset, callithrix jacchus. we compared marmosets which were identified as having dichromatic or trichromatic color vision. within the lgn, the density of p-ir neurones is highest in ...	1998	9682866
reproduction and maintenance of two species of marmoset in captivity.	marmoset monkeys are an useful model to biological human experiments and their development in captivity has been carried out in different environment and feeding conditions. this work presents the development of callithrix jacchus jacchus and callithrix jacchus penicillata in captivity at the vivarium of the centro de biologia da reprodução. couples of marmosets, obtained with the help of the forest institute, were kept in an environment where the temperature was around 22-24 degrees c, with 10 ...	1998	9697652
histopathological characterization of magnetic resonance imaging-detectable brain white matter lesions in a primate model of multiple sclerosis: a correlative study in the experimental autoimmune encephalomyelitis model in common marmosets (callithrix jacchus).	experimental autoimmune encephalomyelitis in the common marmoset, a nonhuman primate species (callithrix jacchus), is a new model for multiple sclerosis. given the close immunological relationship between marmosets and humans, it is an attractive model for investigating immunopathological pathways relevant to multiple sclerosis and to evaluate new treatments for the disease. unlike in the originally documented model, experimental autoimmune encephalomyelitis induced without the use of bordetella ...	1998	9708823
immunoreactive riboflavin carrier protein concentration during ovulatory cycle in the common marmoset (callithrix jachhus): role of estrogen.	common marmoset, a non-human primate, is increasingly being used as a model system in reproductive endocrinology. marmosets do not menstruate but have normal cycle length of 28 +/- 2 days. the presence of protein immunologically and functionally similar to the well characterized chicken riboflavin carrier protein (crcp) has been demonstrated in circulation in pregnant marmosets. marmoset rcp (mrcp) has been partially purified and the molecular weight of the immunoreactive protein is similar to c ...	1998	9717443
molecular cloning in the marmoset shows that semenogelin is not the precursor of the trh-like peptide pglu-glu-pro amide.	two peptides with similar structures to thyrotropin-releasing hormone (trh), pglu-glu-pro amide and pglu-phe-pro amide, have been identified in human seminal fluid and it has been shown that one of these peptides, pglu-glu-pro amide, has the ability to increase the capacitation of sperm cells, consistent with a role in fertility. in order to select a species in which there is a high degree of expression of the genes that code for 'trh-like' peptides, we have determined the levels of these peptid ...	1998	9748547
an evaluation of the marmoset callithrix jacchus (sagüi) as an experimental model for the dyslipoproteinemia of human schistosomiasis mansoni.	human infection with the parasite schistosoma mansoni is a relatively common occurrence in regions of south america and is associated with liver dysfunction and dyslipoproteinemia. specifically, the activity of plasma lecithin:cholesterol acyltransferase (lcat) activity is reduced, the concentration of plasma cholesterol esters falls, phospholipid concentrations are elevated and erythrocyte membranes become cholesterol enriched. previous studies have utilized rodents (rats and mice) as experimen ...	1998	9748601
behavioural effects of subthalamic nucleus lesions in the hemiparkinsonian marmoset (callithrix jacchus).	recent studies in non-human primates support a role for the subthalamic nucleus in the expression of parkinsonian symptomatology, and it has been proposed that subthalamic lesions may provide a surgical treatment for the symptoms of parkinson's disease in humans. we have applied a broad range of behavioural tests to characterize the effects of lesions of the subthalamic nucleus on parkinsonian symptoms in the unilateral 6-hydroxydopamine (6-ohda) lesioned marmoset (callithrix jacchus). thirteen ...	1998	9749730
growth of marmoset monkeys callithrix jacchus in captivity.		1998	9751829
the zoonotic importance of mycobacterium tuberculosis: transmission from human to monkey.	a case of zoonotic mycobacterium tuberculosis infection in a marmoset (callithrix jacchus) is reported. genomic typing of the relevant m. tuberculosis isolates strongly suggests that the marmoset, which was kept as companion animal, acquired the disease from an infected member in the household who had been treated for pulmonary tuberculosis 8 years prior to this case.	1998	9760401