Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| effectiveness of membrane feeding method in relation to development of filarial infective larvae in culex quinquefasciatus. | 1986 | 3309040 | |
| factor influencing acceptance and non-acceptance to dec in a bancroftian endemic area. | 1986 | 3309041 | |
| reduced lymphocyte response to mitogens in patients with bancroftian filariasis. | peripheral blood lymphocytes from patients with acute and chronic wuchereria bancrofti infections responded poorly to concanavalin a, phytohaemagglutinin and pokeweed mitogen when cultured in heat-inactivated pooled normal serum. the lymphocyte response to mitogens in carriers of microfilariae (mff) were normal. the suppression of transformation to mitogens was not reversible by the removal of plastic adherent cells. incubation with mitogens and the adult filarial worm antigen (bma) did not alte ... | 1986 | 2941905 |
| demonstration of species-specific and cross-reactive components of taenia solium metacestode antigens. | analysis of human serum reactivities to antigenic components of soluble taenia solium metacestode proteins showed the predominant presence of determinants shared by t. solium, echinococcus multilocularis and e. granulosus. two polypeptides were demonstrated by sds-page and western blot or enzyme-linked immunoelectrotransfer blot (eitb) assay to bind serum and csf antibodies only from t. solium cysticercosis patients. these species-specific antigenic polypeptides focused between ph 4.6 and 3.9 af ... | 1986 | 3082229 |
| two additional morphological characteristics for differentiating adult wuchereria bancrofti and brugia malayi. | 1986 | 3100162 | |
| differentiation of three developmental stages of bancroftian and malayian filariae in mosquito vectors. | 1986 | 3100178 | |
| [advances in research on the immunopathogenic mechanism of lymphatic filariasis]. | 1986 | 3103893 | |
| defective concanavalin a-induced suppression in bancroftian filariasis. | a concanavalin-a-induced suppressor cell assay was carried out in 10 patients with chronic filarial disease, 13 asymptomatic microfilaria carriers and 7 healthy subjects. both the chronic filarial patients and the asymptomatic microfilaria carriers showed statistically significant reduced suppression indices when compared with the control subjects. the reduction in suppression indices was greater in the microfilaria carriers than in the chronic filarial patients. | 1987 | 2956197 |
| a study of arthritis in papua new guinea. | a study was undertaken of 182 melanesian patients with arthritis who were admitted to three major hospitals in papua new guinea between 1977 and 1982. there were 118 male and 64 female subjects, whose mean ages were 29 years and 25 years respectively. a diagnosis was made in 101 cases (55.5%) but in 81 cases, because assessment and management had been inadequate, a diagnosis could not be made. the commonest cause was infectious arthritis (44%), followed by rheumatoid arthritis (14%), gout (8%), ... | 1987 | 3039954 |
| igg antibody subclasses in human filariasis. differential subclass recognition of parasite antigens correlates with different clinical manifestations of infection. | the four subclasses of igg are distinct in structure, function, and degree of participation in the antibody response to complex antigens. looking for differential responsiveness of potential pathogenetic significance, we have analyzed both quantitatively and qualitatively the filaria-specific igg subclass responses of 20 patients with lymphatic filariasis presenting either with chronic lymphatic obstructive pathology and elephantiasis (cp) or with asymptomatic microfilaremia (mf). subclass-speci ... | 1987 | 3309059 |
| in vitro cultivation of third stage larvae of wuchereria bancrofti to the fourth stage. | third stage larvae of wuchereria bancrofti obtained from laboratory-infected mosquitoes grew and molted to the fourth stage in vitro. the culture medium which supported the best growth and development consisted of a 1:1 mixture (v/v) of two commercially available cell culture media, nctc 135 and iscove's modified dulbecco's medium supplemented with 10% human serum or plasma and an antibacterial/antimycotic mixture. cultures were incubated at 37 degrees c in an atmosphere of either 5% or 8% co2 i ... | 1987 | 3310688 |
| evaluation of specific humoral immune responses in human filariasis. | using the antigens prepared from adult worms of b. malayi and d. immitis, a total of 37 malayan and 150 bancroftian serum samples were analysed for the presence of filarial specific antibodies by counterimmunoelectrophoresis and indirect enzyme linked immunosorbent assay. it was observed that microfilaraemic cases do show good specific humoral immune responses against homologous as well as heterologous antigen. of the two antigens used, b. malayi adult antigen was found to be superior to d. immi ... | 1987 | 3311932 |
| prevalence survey of filariasis in two villages in chingleput district of tamil nadu. | 1987 | 3311986 | |
| immunosuppression in clinical filariasis. | 1987 | 3311987 | |
| the silvered leaf monkey (presbytis cristata) as a model for human bancroftian filariasis. | 1987 | 3312807 | |
| [filariasis caused by wuchereria bancrofti cobbold, 1877 (nematoda: filaroidea). report of a case in cuba]. | 1987 | 3313564 | |
| development of brugia malayi in mongolian gerbils previously exposed to wuchereria bancrofti. | twelve mongolian gerbils, meriones unguiculatus, were infected with 100 third-stage larvae of wuchereria bancrofti. one month later these animals, along with 4 control animals, were given 100 third-stage larvae of brugia malayi. eleven of the 12 experimental animals and the 4 controls survived, and 8 of the experimental animals and all of the controls demonstrated microfilaremia after 3 months. the animals were killed at 6-months post-infection and examined for parasites. one w. bancrofti larva ... | 1987 | 3313736 |
| filariasis in tak province, northwest thailand: the presence of subperiodic variant wuchereria bancrofti. | the microfilariae found in carriers at tak province, northwestern thailand were morphologically and morphometrically studied. it was found that the parasites conformed to that of w. bancrofti microfilaria. the microfilarial periodicity as determined from four carriers was found to be nocturnally (early evening) subperiodic type showing a distinct peak at 1800 hours. | 1987 | 3313738 |
| aedes (finlaya) togoi theobald 1907, chanthaburi strain, a laboratory vector in studies of filariasis in thailand. | 1987 | 3313743 | |
| scanning electron microscopic study of third-stage larva of wuchereria bancrofti and brugia malayi in thailand. | 1987 | 3313744 | |
| filariasis programme--recife--brazil. | 1987 | 2908187 | |
| an analysis of in vitro b cell immune responsiveness in human lymphatic filariasis. | the immunoregulatory mechanisms involved in b cell function in patients with varying clinical manifestations of bancroftian filariasis were examined by studying the ability of peripheral blood mononuclear cells (pbmc) or pbmc subpopulations from patients with elephantiasis, asymptomatic microfilaremia (mf), and acute tropical pulmonary eosinophilia (tpe) to produce polyclonal and parasite-specific antibody in vitro, both spontaneously and in response to a mitogen (pwm) and to parasite antigen. w ... | 1987 | 3295043 |
| a study of the antigen, antibody and immunecomplex levels in wuchereria bancrofti filariasis with reference to clinical status. | circulating antigens, antibodies to somatic and sheath components of microfilariae (mf) and immune complexes were determined in parallel in different categories of wuchereia bancrofti infection using, respectively, reverse indirect haemagglutination (riha), indirect haemagglutination (iha), indirect immunofluorescent (ifa) and polyethylene glycol (peg) precipitation assays. rabbit hyperimmune anti-w. bancrofti mf serum and mf homogenates were used as reagents. appreciable levels of antigens and ... | 1987 | 3295279 |
| the wellcome trust lecture. inflammatory responses to filarial connective tissue parasites. | the inflammatory responses to lymphatic filariae and to onchocerca volvulus are reviewed with particular attention to evolutionary biology; inflammatory host spectrum; non-specific components; immunoregulation; immune evasion versus immunomodulation; chronic tissue damage and scarring and disease models. basic principles of pathogenesis are emphasized, comparisons drawn with schistosome infection, and critical items of missing information are highlighted. | 1987 | 3295688 |
| the spectrum of disease in lymphatic filariasis. | lymphatic filariasis affects predominantly the poorer sector of a community, who can least afford to have the disease. according to an estimate by the world health organization in 1984, more than 90 million people are currently infected. it is postulated that the different disease manifestations of filariasis are caused by different host immune responses. an understanding of the clinical spectrum of lymphatic filariasis is essential for the effective treatment and control of the disease, and for ... | 1987 | 3297555 |
| antibody responses to human lymphatic filarial parasites. | the lymphatic filarial parasites, brugia and wuchereria, continue to present an immunological puzzle, particularly with respect to the development of natural resistance or damaging disease. we have approached this question by examining humoral responses to a few defined antigens of selected interest from these parasites, using sera from each category in the spectrum of filarial disease. many antigens, such as the major adult surface protein of mr 29,000 (29k), appear to be recognized at all stag ... | 1987 | 3297556 |
| cellular unresponsiveness in patients with soluble circulating antigens in bancroftian filariasis. | 1987 | 3298028 | |
| acute tropical pulmonary eosinophilia. characterization of the lower respiratory tract inflammation and its response to therapy. | although acute tropical pulmonary eosinophilia (tpe) is well recognized as a manifestation of filarial infection, the processes that mediate the abnormalities of the lung in tpe are unknown. to evaluate the hypothesis that the derangements of the lower respiratory tract in this disorder are mediated by inflammatory cells in the local milieu, we utilized bronchoalveolar lavage to evaluate affected individuals before and after therapy. inflammatory cells recovered from the lower respiratory tract ... | 1987 | 3298321 |
| a monoclonal antibody-based enzyme immunoassay for detecting parasite antigenemia in bancroftian filariasis. | we evaluated a monoclonal antibody-based enzyme immunoassay for detecting soluble parasite antigen in sera collected in an area in south india endemic for wuchereria bancrofti. filarial antigen was detected in sera from 56 of 57 microfilaremic patients, 9 of 64 aminofilaremic patients with clinical filariasis, and 11 of 70 endemic controls. antigen was not detected in sera from patients from nonendemic areas who had a variety of other filarial and nonfilarial helminth infections. parasite antige ... | 1987 | 3298458 |
| circulating parasite antigen(s) in lymphatic filariasis: use of monoclonal antibodies to phosphocholine for immunodiagnosis. | hybridoma cell lines producing monoclonal antibodies (mab) against a 200 kd antigen found circulating in the sera of microfilaremic patients infected with wuchereria bancrofti were obtained by immunizing mice with a partially purified antigen preparation. a sensitive mab (ca101)-based elisa for measuring circulating parasite antigen was capable of detecting antigen in the sera of 93% of patients with microfilaremia, 46% of those with lymphatic obstruction, and 56% of patients with tropical pulmo ... | 1987 | 2437195 |
| immunodiagnosis of bancroftian filariasis. | the development of immunodiagnostic tests (idts) for bancroftian filariasis must be aimed at defined objectives, such as the determination of exposure rates, the detection of microfilaraemia and the diagnosis of clinical filariasis. assays for both antibody and antigen detection are necessary. antigen determination may be more appropriate in the detection of microfilaraemia, but for clinical filariasis, antibody determination may prove more useful. the microfilarial surface antigens are very goo ... | 1987 | 2439264 |
| dose-ranging study of ivermectin in treatment of filariasis due to wuchereria bancrofti. | 1987 | 2883362 | |
| lectin-binding characteristics of wuchereria bancrofti microfilariae. | the binding of 10 different lectins to the surface of microfilariae of wuchereria bancrofti has been investigated. wheat germ agglutinin (wga) and helix pomatia lectin (hpa) bound specifically to the sheathed microfilariae indicating the presence of n-acetyl-d-glucosamine and n-acetyl-d-galactosamine respectively on the surface. exsheathed microfilariae did not react with any of the lectins. treatment of sheathed microfilariae with proteases resulted in increased binding of wga and hpa. such tre ... | 1987 | 2884837 |
| epidemiology of lymphatic filariasis. | human lymphatic filariasis is caused mainly by wuchereria bancrofti, brugia malayi and brugia timori. of the estimated 90.2 million people infected, more than 90% have bancroftian and less than 10% brugian filariasis. the distribution and transmission of the disease are closely associated with socioeconomic and behavioural factors in endemic populations. urban w. bancrofti infection, as seen in south-east asia, is related to poor urban sanitation, which leads to intense breeding of culex quiquef ... | 1987 | 2885159 |
| [lymphatic filariasis in vanuatu]. | lymphatic filariasis, in the archipelago of vanuatu, is due to wuchereria bancrofti. the vector is anopheles farauti, endophilic mosquito, which transmits also malaria. the level of endemicity was very high in the beginning of this century (microfilariae in blood: 60.9%, elephantiasis: 21%), and has dramatically decline now by detection and treatment of sick people (70 cases in 1986), mass chimioprophylaxis and protection against the vectors. but these actions must be continued to obtain the era ... | 1987 | 2894256 |
| identification and partial characterization of a parasite antigen in sera from humans infected with wuchereria bancrofti. | the purpose of this study was to identify and characterize soluble parasite antigens present in sera from humans infected with the filarial nematode wuchereria bancrofti. affinity chromatography and immunoblot methods were used to demonstrate a 200,000 m.w. circulating parasite antigen in sera from infected humans which corresponded to an antigen released by adult w. bancrofti during in vitro culture. two monoclonal antibodies were produced to this antigen by immunizing mice with antigens from d ... | 1987 | 3553330 |
| the disappearance of bancroftian filariasis from charleston, south carolina. | i suggest the hypothesis that bancroftian filariasis, endemic since the early days of slavery in charleston, south carolina, disappeared around 1930 by virtue of the long-term effects of a municipal sewerage-water system begun in the 1890s or thereabouts. these public works, originally intended to abate typhoid and related diseases, helped to eliminate filariasis by reducing the availability of polluted domestic waters which are the preferred breeding sites for the urban vector, culex quinquefas ... | 1987 | 3300389 |
| [studies on the role of residual microfilaremia in bancroftian filariasis transmission in controlled areas]. | 1987 | 3304654 | |
| [determination of circulating antigens in human filariasis by means of a modified sandwich enzyme-linked immunosorbent assay (ms-elisa) using monoclonal antibodies]. | 1987 | 3304699 | |
| a survey of bancroftian filariasis in the dominican republic. | 1987 | 3305853 | |
| filariasis of the breast. | filariasis of the breast is usually seen in endemic areas. involvement may, however, present years after leaving an endemic area and be associated with circulating microfilariae. we describe the findings in a woman who developed a breast mass three years after a visit to her native india. | 1987 | 3307689 |
| [longitudinal surveillance in areas with bancroftian filariasis virtually eradicated in guizhou]. | 1987 | 3308161 | |
| [estimation of some entomological parameters in relation to the transmission of bancroftian filariasis]. | 1987 | 3308162 | |
| [epidemiological features of residual infection foci of filariasis in controlled areas and purifying measures]. | 1987 | 3308362 | |
| filarial chyluria: an immunological and renal function study. | 1987 | 3308835 | |
| parasite antigens in sera and urine of patients with bancroftian and brugian filariasis detected by sandwich elisa with monoclonal antibodies. | we developed a sandwich enzyme-linked immunosorbent assay to detect circulating parasite antigens in human lymphatic filariasis. the assay utilizes a polyclonal rabbit antifilarial antiserum to capture, and a monoclonal antibody to identify, circulating parasite antigen. using this assay, we found that greater than 95% of sera from microfilaremic donors with bancroftian or brugian filariasis, approximately 60% of sera from microfilaremic patients with hydroceles, chyluria, or elephantiasis, and ... | 1987 | 3555138 |
| immunochemical characterization and biosynthesis of major antigens of iodo-bead surface-labeled brugia malayi microfilariae. | the objectives of the present study were to identify and characterize biochemically the major antigens of brugia malayi microfilariae, a filarial parasite that infects humans. igg antibodies in sera of mice which had cleared parasites from the bloodstream reacted with 30, 55, 94 and 150 kda molecules of living microfilariae radioiodinated by the iodo-bead method. sera of humans infected with the related filariae wuchereria bancrofti, loa loa or onchocerca volvulus immunoprecipitated molecules of ... | 1987 | 3574345 |
| the cat infected with brugia pahangi as a model of human filariasis. | the responses of cats to brugia pahangi, which parasitizes them in nature, mimic those of humans to brugia malayi and wuchereria bancrofti in many important respects. it is likely that many of the features of the relationship between host and parasite that can be studied in cats infected with b. pahangi also apply to humans, but for a variety of practical reasons cannot be demonstrated in humans. both immunologically and parasitologically there is a profound difference between b. pahangi-infecte ... | 1987 | 3595322 |
| characterization of an onchocerca-specific dna clone from onchocerca volvulus. | a genomic library of a savanna isolate of onchocerca volvulus was screened to detect recombinant plasmids containing highly repeated dna sequences of this parasite. four recombinant plasmids were identified which hybridized specifically to onchocerca dna, but not to dna from humans, black flies, brugia malayi, b. pahangi, or wuchereria bancrofti. the recombinant plasmids had a low level of homology to dirofilaria immitis. all recombinant plasmids contain related dna sequences based on southern h ... | 1987 | 3661830 |
| parasite-specific anergy in human filariasis. insights after analysis of parasite antigen-driven lymphokine production. | the antigen-specific immune unresponsiveness seen in bancroftian filariasis was studied by examining lymphokine production in peripheral blood mononuclear cells (pbmc) or pbmc subpopulations from 10 patients with asymptomatic microfilaremia, 13 patients with elephantiasis and 6 normal north americans. in each group of patients, the kinetics of the lymphokine response and the response to mitogens and nonparasite antigens did not differ significantly. in marked contrast, when antigen-induced lymph ... | 1987 | 3553242 |
| retroperitoneal cyst of filarial origin. | 1987 | 3320023 | |
| study of the relation between tissue typing and occurrence of filariasis and its complications in egypt. | 1987 | 3320221 | |
| [filarial multiparasitism in the savannah zone in burkina faso]. | from june 1985 to may 1986, 1.209 consulting patients were examined for filariae in skin and blood. among patients with microfilariae 17% had associations of filarial infections. the multiple infections rate seemed more important in man than woman and increased with age. the results showed that associations were not due to chance only. the frequencies of associations between dipetalonema perstans and onchocerca volvulus at one hand, dipetalonema perstans and wuchereria bancrofti on the other han ... | 1987 | 3323769 |
| wheat germ agglutinin specifically binds to the surface of infective larvae of wuchereria bancrofti. | 1987 | 3325623 | |
| clinical manifestations of wuchereria bancrofti filariasis in an endemic village in the nile delta. | 1987 | 3327478 | |
| the pathology of lymphoreticular and genital tissues of silvered leaf monkeys (presbytis cristata) experimentally infected with wuchereria bancrofti. | the discovery of the silvered leaf monkey, presbytis cristata, as a suitable experimental host for the human filarial parasite, wuchereria bancrofti, opened the door for major advances in our understanding of the disease caused by this parasite. to study the pathogenesis of bancroftian filariasis in this model, 15 adult p. cristata which had been experimentally infected with 250 infective third-stage larvae of the parasite were examined. after inoculation with larvae, the monkeys were maintained ... | 1987 | 3327870 |
| natural infections of wuchereria bancrofti in aedes (stegomyia) polynesiensis and aedes (finlaya) samoanus in samoa. | seven years after the 2nd mass treatment of the population with diethylcarbamazine, transmission of subperiodic wuchereria bancrofti was studied in four villages in samoa during one year by means of biting catches of aedes polynesiensis and a. samoanus. 2 villages were coastal, one inland bush and the other an inland coconut plantation community. overall infection and infective rates from 6702 ae. polynesiensis were 0.84 and 0.27% respectively, and the infection rate from 2858 ae. samoanus, coll ... | 1987 | 3328327 |
| distribution of vectors, transmission indices and microfilaria rates of subperiodic wuchereria bancrofti in relation to village ecotypes in samoa. | aedes polynesiensis and ae. samoanus biting densities and wuchereria bancrofti infection and infective rates were studied in 47 villages throughout the islands of samoa upolu, manono and savaii during 1978-79, and microfilaria (mf) rates were surveyed in 28 of the villages. the mf rate was correlated with both infection and infective rates of ae. polynesiensis in upolu, but not of ae. samoanus. in upolu, ae. polynesiensis was apparently the major vector. it was relatively more abundant in more c ... | 1987 | 3328328 |
| bancroftian filariasis in coastal north trinidad: the effects of mass chemotherapy using spaced doses of diethylcarbamazine citrate on human microfilaraemias and vector infection rates. | the effects of a mass chemotherapy programme using spaced doses of diethylcarbamazine citrate on wuchereria bancrofti microfilaraemias and vector infection rates were studied in an isolated rural community of 650 people in north trinidad where a microfilaria rate of 15% had previously been recorded. a single oral dose of 6 mg/kg body weight was given at monthly intervals for one year. after 6 months, 79% (52/66) of persons previously microfilaraemic had become negative. after 12 months the negat ... | 1987 | 3328349 |
| a mark-recapture experiment with the filariasis vector anopheles punctulatus in papua new guinea. | a capture-recapture experiment with the filariasis vector anopheles punctulatus from papua new guinea (png) is described. eight hundred and ninety-seven engorged females collected indoor resting or in landing catches were released, and 82 were subsequently recaptured. infection rates were higher in recaptured mosquitoes than in unmarked ones. recapture rates declined exponentially with distance from the release site, but an infected female was recaptured 1.8 km from the release site. the estimat ... | 1987 | 3328568 |
| fractionation and characterization of urinary filarial antigen in bancroftian filariasis. | urine samples from microfilaraemic patients were concentrated and fractionated by gel chromatography on ultrogel aca 44. four protein fractions labelled as ufa c1, ufa c2, ufa c3 and ufa c4 were tested for filarial antigenicity by sandwich elisa. ufa c1 and ufa c2 showed antigenic activity. on further analysis by sds-page, ufa c1 and ufa c2 showed antigenic components with mw ranging from 10.4 k to 123 k. ufa c1-1 and ufa c2-2 showed high antigen titre in elisa. urinary albumin was observed as a ... | 1987 | 3329520 |
| [effectiveness of mass chemotherapy campaigns with diethylcarbamazine on blood microfilaria of wuchereria bancrofti in mayotte]. | an evaluation of the microfilarial index has been carried out in a randomised population, during april and may 1986, to determine the efficacy of long course mass chemotherapy. a single dose of dec at 6 mg/kg was distributed to the whole population of the island, every 4 months, in 1985 and 1986. the survey was done three months after the treatment. 1,307 thick blood films have been collected in night-time. the prevalence of microfilaremia was 1.9% as compared with 17.1% in 1981 in the condition ... | 1987 | 3329988 |
| prophylactic effect of diethylcarbamazine on wuchereria bancrofti filariasis. | 1987 | 3331391 | |
| prophylactic effect of diethylcarbamazine on w. bancrofti filariasis. | 1987 | 3333774 | |
| control of bancroftian filariasis in a rural area through selected treatment with diethylcarbamazine. | 1987 | 3333775 | |
| laboratory parameters in early and late cases of bancroftian filariasis in an endemic area. | 1987 | 3333778 | |
| microfilariae in fine needle aspirates from epididymal lesions. | microfilariae of wuchereria bancrofti were observed in fine needle aspiration smears from three epididymal nodules, and degenerating microfilariae suggestive of brugia malayi were found in the smears from a fourth case. the smears in all four cases showed a polymorphonuclear inflammatory cell component as well as epithelioid cell granulomata. while blood eosinophilia was present in all four cases, eosinophilia was present in the aspiration smears in only one case. microfilariae could be demonstr ... | 1987 | 3468719 |
| characterization of stage-specific antigens of infective larvae of the filarial parasite brugia malayi. | three stages of the filarial parasite brugia malayi (infective third stage larvae, adult worms, and microfilariae) were analyzed for differences in their protein composition by two-dimensional gel electrophoresis. comparison of protein profiles of the different stages showed both identical polypeptides (reflecting common proteins) and polypeptides specific for each stage. three polypeptides present only in infective stage larvae were seen at 72 kda at an isoelectric point (pi) of 4.98 (p72), 30 ... | 1988 | 3346549 |
| characterization of a monoclonal antibody against infective larvae of brugia malayi. | monoclonal antibodies were produced following immunization of mice with live infective larvae of brugia malayi. one of these, 46.08.76, is an antibody that promotes adherence of mouse peritoneal macrophages and human peripheral blood leucocytes to the infective larvae of b. malayi and wuchereria bancrofti, respectively, and kills them. fresh normal serum, as a source of complement, augments this effect. the same monoclonal antibody conferred 89% protection to jirds (meriones unguiculatus) agains ... | 1988 | 3384450 |
| microfilarial surface carbohydrates as a function of developmental stage and ensheathment status in six species of filariids. | the lectin-binding properties of microfilariae of onchocerca volvulus, o. lienalis, brugia pahangi, wuchereria bancrofti, dirofilaria immitis, and monanema (= ackertia) marmotae share a number of characteristics. carbohydrates specific for lectins are associated with the egg shell or sheath. n-acetyl-d-glucosamine is the predominant carbohydrate associated with the ensheathed forms with lesser quantities of d-galactose and/or alpha-lactose and d-galactosamine. the density of these carbohydrates ... | 1988 | 3418456 |
| application of biotechnology in the identification of filarial larva in mosquitoes. | current methods for detecting and identifying filariae in mosquitoes are laborious and time consuming. with today's technology, we can reasonably expect development of rapid, sensitive and specific assays for detecting and identifying filariae in naturally infected mosquito populations. progress in developing such assays is reviewed. | 1988 | 2900557 |
| bancroftian filariasis in the igwun basin, nigeria. an epidemiological, parasitological, and clinical study in relation to the transmission dynamics. | a 12-month field and laboratory study was carried out to determine the epidemiology, clinical features, and transmission dynamics of bancroftian filariasis in the igwun basin, nigeria. a total of 1,418 individuals (768 males, and 650 females) were examined for clinical signs of filariasis. 690 day provocative blood samples (dps), and 728 night blood samples (nbs) were examined for microfilaremia. 14.3% of males and 11.1% of females were mf positive. 5.8% of dps, and 19.5% of the nbs were mf posi ... | 1988 | 2901204 |
| investigations of filarial worms of man in metropolitan lagos. short communication. | 1988 | 2901210 | |
| microfilaraemia, filarial antibody, antigen and immune complex levels in human filariasis before, during and after dec therapy. a two-year follow-up. | a study on the effect of dec therapy on microfilaraemia and the immune status in 27 patients with w. bancrofti infection was carried out for two years. persistence of microfilaraemia was observed in 4 out of 27 cases after one course of dec therapy and were treated again for one week. on further follow-up, none was microfilaraemic upto day 60. the mean filarial antibody titres of igm and igg showed a gradual decrease as assessed by enzyme linked immunosorbent assay (elisa). the mean titres of ci ... | 1988 | 2903626 |
| a study of bancroftian filariasis on the islands of batan and rapu rapu, philippines. | the islands of batan and rapu rapu in southeastern luzon, philippines, were surveyed for filariasis from november 1984 to may 1985. microfilariae of bancroftian filariasis were detected in 10.5% of the people over one year of age. microfilarial rates and intensity of infection were the same for males and females. the highest rates for both sexes were in the 56- to 60-year-old age group. aedes poicilius, which breeds in abaca and banana plants, was found to be very anthropophilic, comprising 96.5 ... | 1988 | 2906482 |
| quantitation of antibodies to infective larvae in wuchereria bancrofti filariasis. short communications. | 1988 | 2907266 | |
| filariasis in the igwun river basin, nigeria: an epidemiological and clinical study with a note on the vectors. | in a cross-sectional, epidemiological and parasitological study of human filariasis, 845 individuals were examined in settlements along the igwun basin, imo state, nigeria. four different filarial nematode species were identified. two hundred and fifty-six (30.3%) of the individuals examined were positive for onchocerca volvulus, 113 (13.4%) for mansonella perstans, 76 (9.6%) for wuchereria bancrofti and 77 (9.1%) for loa loa. microfilarial rates increased with age of individuals and showed a te ... | 1988 | 3041931 |
| diagnosis of bancroftian filariasis by detection of circulating antigens by counterimmunoelectrophoresis. | 1988 | 3047273 | |
| bancroftian filariasis in the igwun basin, nigeria: an epidemiological, parasitological, and clinical study in relation to the transmission dynamics. | a 12-months study on bancroftian filariasis was carried out in the igwun basin, nigeria. a total of 1,418 individuals (768 males, and 650 females) were examined for microfilaremia and clinical filarial stigmata. there were 14.3% and 11.1% male and female point prevalence rates, respectively, and an overall prevalence of 12.8%. prevalence rates and microfilarial density increased with age. the highest mff density of 35 mff/20 ml blood occurred in the 40-49 year old male individuals. disease rates ... | 1988 | 3049274 |
| evaluation of integrated vector control measures on filariasis transmission in pondicherry. | 1988 | 3049328 | |
| persistence of microfilaremia in bancroftian filariasis after diethylcarbamazine citrate therapy. | of 58 patients in leogane, haiti, infected with wuchereria bancrofti and treated with diethylcarbamazine citrate (dec-c) at 6 mg/kg per day for 12 days (= 72 mg/kg), 38 (66%) of 58 continued to harbor low numbers of circulating microfilariae (median microfilariae could be demonstrated in 7 (37%) of 19 patients, with a median microfilarial density of 8 mf/ml. three patients who continued to have circulating microfilariae after two courses of dec-c were treated a third time. two (67%) of the three ... | 1988 | 3051291 |
| a quantitative analysis of the diagnostic value of diethylcarbamazine provocation in endemic wuchereria bancrofti infection. | the efficiency (delta) of the day-time provocative effect of diethylcarbamazine (dec) on the circulation of microfilariae (mf) of nocturnally periodic wuchereria bancrofti compared with the night mf count was evaluated in terms of sensitivity and specificity. in one test, the mean mf count for finger-blood samples from the same person on 3 successive nights was compared with the day-time post-dec count; another test compared the mf count in one night-time finger-blood sample with the following d ... | 1988 | 3051541 |
| factors affecting transmission of wuchereria bancrofti by anopheline mosquitoes. 1. uptake of microfilariae. | ingestion of wuchereria bancrofti microfilariae (mf) from humans by 639 anopheles gambiae, 557 an. arabiensis, 117 an. melas and 9 an. funestus was investigated. the mf densities in blood fell into 3 groups; 0-32mf/ml, 107-122 mf/ml and 421-1140 mf/ml. in an. gambiae and an. arabiensis percentage of mosquitoes ingesting mf was strongly associated with mf density in host blood; in an. melas the association was much weaker. mean number of mf ingested per mosquito was also strongly correlated to mf ... | 1988 | 3051542 |
| factors affecting transmission of wuchereria bancrofti by anopheline mosquitoes. 2. damage to ingested microfilariae by mosquito foregut armatures and development of filarial larvae in mosquitoes. | microfilariae (mf) of wuchereria bancrofti from the midgut of 639 anopheles gambiae, 557 an. arabiensis, 117 an. melas and 9 an. funestus were examined immediately after the mosquitoes had fed on carriers with different densities of mf. the percentages of mf damaged during ingestion were 57.1-60.0 in an. gambiae, 33.3-50.6 in an. arabiensis and 38.7-55.7 in an. melas. in each species the percentage of mf damaged was independent of mf density in the human host. a further 3657 an. gambiae, 2875 an ... | 1988 | 3051543 |
| [study on the role of low density microfilaremia cases in the transmission of filariasis in late stage of filariasis control]. | 1988 | 3052910 | |
| circulating antibodies and antigens in presbytis monkeys infected with the filarial parasite wuchereria bancrofti. | levels of circulating filarial antigen, and humoral antibody to other defined antigenic targets, were measured over the course of experimental infection of three presbytis cristatus monkeys with wuchereria bancrofti. circulating antigen levels, measured with an anti-phosphorylcholine monoclonal antibody, varied widely although all animals were positive for some period of the infection. circulating antigen levels tended to be inversely related to the titre of anti-phosphorylcholine antibody, and ... | 1988 | 3057591 |
| uptake and development of wuchereria bancrofti in aedes aegypti and haitian culex quinquefasciatus that were fed on a monkey with low-density microfilaremia. | colonized mosquitoes of culex quinquefasciatus (haitian strain) and aedes aegypti (liverpool strain) were blood fed on a patas monkey (erythrocebus patas) that had been experimentally infected with the haitian strain of wuchereria bancrofti and harbored a consistently low microfilaremia (1-3 mf per 20 mm3). both species ingested more than twice the expected number of microfilariae (mf), i.e. 1.9 and 0.77 mf per mosquito, respectively. however, at 10-16 hours post ingestion only 4.2% of the mf ha ... | 1988 | 3057592 |
| comparative densities of wuchereria bancrofti microfilaria in paired samples of capillary and venous blood. | concurrent finger-prick and venous blood samples were obtained from 43 patients infected with wuchereria bancrofti. microfilariae were counted in blood smears and on nuclepore filters. based on the numbers of microfilariae in 20-microliters finger-prick samples, an expected (theoretical) number of microfilariae in venous samples was calculated. this expected value was compared to the actual number of microfilariae present in venous blood. the actual number of microfilariae present ranged from 0. ... | 1988 | 3067320 |
| practical and effective dose schedule of diethylcarbamazine (dec) against bancroftian filariasis for mass therapy campaigns. | 1988 | 3068306 | |
| [an unusual case of mediastinal lymphatic filariasis with pulmonary artery stenosis]. | 1988 | 3068713 | |
| use of mebendazole in combination with dec in bancroftian filariasis. | 1988 | 3071522 | |
| [studies on the indirect fluorescent antibody test for diagnosis and surveillance of human filariasis]. | 1988 | 3072113 | |
| lymphatic filariasis: some recent trends and advances. | 1988 | 3073871 | |
| epidemiology of wuchereria bancrofti in leogane, haiti. | a survey for wuchereria bancrofti in leogane, haiti, revealed that 140 of 421 individuals (33%) had a patent infection, of which 40% lived in the suburban outskirts of the city. the median microfilaria density was 19.1 per 20 mm3 of blood for suburban dwellers compared with only 8.8 for those living in the city. the vector, culex quinquefasciatus (say), breeds mostly in and around numerous rum distilleries, located exclusively around the periphery of the city, and this undoubtedly accounts for t ... | 1988 | 3075358 |
| the effect of diethylcarbamazine treatment of bancroftian filariasis on the immunological reactivity of microfilaraemic individuals. | patent filarial infection has been correlated with a profound suppression of humoral and cellular responses to filarial antigens. in the present study, the filarial antigen-specific humoral and cellular reactivity of 30 haitian subjects with patent wuchereria bancrofti infection was monitored before and after treatment with diethylcarbamazine. microfilarial density was reduced from a pre-treatment mean of 1778/ml to 9/ml, with residual microfilaraemias detectable in 10 subjects. peripheral blood ... | 1988 | 3075359 |
| diethylcarbamazine prophylaxis against bancroftian filariasis given by a member of the local community in kenya. | 1988 | 3075443 | |
| [diagnosis of filariasis by indirect fluorescent antibody test with sonicated microfilariae malayi as antigen]. | 1988 | 3075522 | |
| [transectional surveillance in west hubei with filariasis basically eradicated]. | 1988 | 3075527 | |
| detection of infective larval antigens in bancroftian filariasis. | 1988 | 3076164 | |
| wuchereria bancrofti larvae in naturally infected culex quinquefasciatus. | 1988 | 3076752 |