Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| antibacterial activity in vitro of cefpirome against clinical isolates causing sexually transmitted diseases. | the in-vitro activity of cefpirome was compared with other antibiotics against organisms causing sexually transmitted diseases (std). the excellent activity of cefpirome against neisseria gonorrhoeae (mic90 1.0 mg/l), haemophilus ducreyi (mic90 0.5 mg/l), and gardnerella vaginalis (mic90 1.0 mg/l) suggests that this agent might be useful in the empirical treatment of a variety of venereal diseases. | 1992 | 1318294 |
| in vitro activity of sparfloxacin and other antimicrobial agents against genital pathogens. | the in vitro activity of sparfloxacin was determined for 60 strains of neisseria gonorrhoeae, 15 strains of chlamydia trachomatis and 40 strains each of gardnerella vaginalis, mycoplasma hominis, and ureaplasma urealyticum and compared with those of ampicillin, azithromycin, clarithromycin, erythromycin, ofloxacin, temafloxacin and tetracycline. sparfloxacin was active against all the strains studied and appeared to be the most potent quinolone tested. sparfloxacin had the lowest mics against n. ... | 1992 | 1337506 |
| vaginal microbial flora as a cofactor in the pathogenesis of uterine cervical intraepithelial neoplasia. | the vaginal microbial flora of 106 women with histopathologically confirmed cervical intraepithelial neoplasia and 79 women without disease, was evaluated for gardnerella vaginalis, trichomonas vaginalis, candida albicans and other yeasts. flora morphology was assessed by gram staining of secretions. cervical cultures were examined for herpes simplex virus, cytomegalovirus and neisseria gonorrhoeae. chlamydia trachomatis antigens in cervical secretions were detected by enzyme immunoassay. human ... | 1992 | 1351005 |
| high levels of gardnerella vaginalis detected with an oligonucleotide probe combined with elevated ph as a diagnostic indicator of bacterial vaginosis. | we have demonstrated a new approach to diagnosing bacterial vaginosis (bv) that is based on measuring the concentration of gardnerella vaginalis in vaginal fluid with dna probes. g. vaginalis is virtually always present at high concentrations in women who have bv but is also detected frequently in normal women, usually at concentrations of less than 10(7) cfu/ml of vaginal fluid. elevated vaginal ph is another sensitive indicator of bv, although it can occur in conjunction with other conditions. ... | 1992 | 1372621 |
| physical characterization of the pore forming cytolysine from gardnerella vaginalis. | the cytolytic toxin (ctox) produced by gardnerella vaginalis is able to form voltage-dependent cationic channels when incorporated in lipid membranes (moran et al. (1991) febs lett. 283, 317-320). osmotic protection experiments show that toxin incorporated in human erythrocytes forms pores between 18 a and 28 a in diameter. a hypothesis of pore formation as a primary event to produce cytolysis is proposed. the ctox activity increases when cells are depolarized by increasing the extracellular k+ ... | 1992 | 1384598 |
| a microbiological study of vaginal discharge in women attending a malaysian gynaecological clinic. | vaginal discharge is a common complaint of women attending gynaecological clinics. the purpose of this study was to compare the occurrence of commonly implicated microorganisms in vaginal discharge amongst women with or without the complaint, attending a gynaecological and family planning clinic. the association of gardnerella vaginalis with bacterial vaginosis was also studied. it was found that there were no significant differences between the cases and controls in the isolation rate of gardne ... | 1992 | 1387449 |
| [epidemiological factors and vaginal flora changes in vaginal bacteriosis (bacterial vaginosis)]. | the aim of this study was to know the modifications of the vaginal bacterial flora that occurs in bacterial vaginosis and to know the involvement of these microorganisms and the influence of several epidemiologic factors in the etiology of this disease. | 1992 | 1391016 |
| inflammation on the cervical papanicolaou smear: the predictive value for infection in asymptomatic women. | the clinical significance of inflammation on the cervical papanicolaou (pap) smear of asymptomatic women is unknown. this study assessed the possible association between inflammation on pap smears with the presence of cervical/vaginal pathogens. | 1992 | 1397815 |
| a collaborative study of the in-vitro sensitivity to rp 59500 of bacteria isolated in seven hospitals in france. | the in-vitro activity of rp 59500 was determined against 1051 recent clinical bacterial isolates. the susceptibility to rp 59500 was determined with an agar dilution technique for all the isolates, while mics and mbcs were determined for 82 selected strains in broth. isolates of both staphylococcus aureus and coagulase-negative staphylococci appeared to be potentially susceptible to rp 59500, independent of susceptibility to methicillin or mls resistance. (s. aureus: methicillin-sensitive, mic90 ... | 1992 | 1399951 |
| heterogeneity in restriction patterns of gardnerella vaginalis isolates from individuals with bacterial vaginosis. | this study was undertaken to resolve the genetic make up of gardnerella vaginalis present in bacterial vaginosis (bv). dna from several g. vaginalis isolates from within and between individual bv patients were compared by bamhi, clai and ecori restriction endonuclease analysis (rea) followed by a restriction fragment length polymorphism (rflp) study, utilizing a 5.7-kb bamhi g. vaginalis atcc14018 dna probe. four g. vaginalis isolates from one patient (gvp-062) were composed of 3 different bioty ... | 1992 | 1410795 |
| infection and labor. viii. microbial invasion of the amniotic cavity in patients with suspected cervical incompetence: prevalence and clinical significance. | the purpose of this study was to determine the prevalence and clinical significance of microbial invasion of the amniotic cavity in patients presenting with cervical dilatation in the midtrimester of pregnancy. | 1992 | 1415396 |
| [isolation and identification of gardnerella vaginalis in women with symptoms of bacterial vaginosis]. | 70 samples of vaginal secretions were collected from women with bacterial vaginosis syndrome, that were attended in nuevo veranillo' health center. all samples were tested in order to determinate the presence of amine and to gram'methods stain to observe the morphologic characteristics of the "clue" cells (epithelial cells with adhered bacteria). samples were cultured in a selective media of blood agar in columbia base with colistine and nalidixic acid, and incubated in an environment of co2 at ... | 1992 | 1439008 |
| diagnosis of bacterial vaginosis in a routine diagnostic laboratory. | vaginal swabs from 299 hospital and general practitioners' patients were examined for gardnerella vaginalis by gram film and by culture, g. vaginalis was isolated in 12% of cultures. comparison between the 'clue' cell and culture methods suggested that the former is a rapid, acceptable routine screening method for the detection of g. vaginalis. the value of the traditional method of identifying g. vaginalis by sensitivity testing is questioned. all specimens were also examined by gram film and c ... | 1992 | 1453913 |
| [benzidamine in the topical treatment of vaginitis caused by gardnerella vaginalis]. | the present clinical trial has been carried out in order to evaluate the efficacy of benzydamine in treatment of vaginitis caused by gardnerella vaginalis. fifty women affected by this specific pathology have been submitted to topical treatment with 0.5% benzydamine vaginal cream. the treatment has been carried out for 9 consecutive days using a local application of benzydamine twice a day. the clinical result was evaluated after 12 and 60 days. the following parameters were taken into considera ... | 1992 | 1480306 |
| vaginitis in non pregnant women in haryana. | study was carried out in 100 patients of non-specific vaginitis (nsv) to find out the incidence of vaginitis due to g. vaginalis. out of a total of 100 subjects 20 were positive for g. vaginalis as compared to only 6 in equal number of normal matched controls. one positive specimen showed concomitant presence of c. albicans and e. coli was found in another positive specimen. presence of amines and clue cells in the discharge did not correlate with the isolation rate of g. vaginalis, thus emphasi ... | 1992 | 1483712 |
| gardnerella vaginalis infection and sexual contact in female children. | gardnerella vaginalis (gv) infection has been reported as being acquired via sexual contact in adults and as an indicator of sexual contact in female children (dejong, 1985). the purpose of this study was to determine if gv infection was more commonly found in 191 female children who gave a history of sexual contact and/or were infected with neisseria gonorrhoeae (gc) or chlamydia trachomatis (ct) (group 1), compared with 144 female children evaluated for possible sexual abuse and found to have ... | 1992 | 1486513 |
| effects of chlorhexidine gluconate douche on normal vaginal flora. | the effects of a 0.5% aqueous chlorhexidine gluconate (chg) douche on the normal vaginal flora of twenty healthy nonpregnant volunteers were investigated. the douche was applied in a premeasured 180-ml quantity daily for 7 consecutive days. specimens for aerobic and anaerobic culture of the vaginal flora were obtained on 3 occasions from each volunteer, once before and twice after chg use. the culture results were analyzed qualitatively and quantitatively. a blood sample was also collected withi ... | 1992 | 1487182 |
| gardnerella vaginalis: characteristics, clinical considerations, and controversies. | the clinical significance, gram stain reaction, and genus affiliation of gardnerella vaginalis have been controversial since gardner and dukes described the organism as the cause of "nonspecific vaginitis," a common disease of women which is now called bacterial vaginosis. the organism was named g. vaginalis when taxonomic studies showed that it was unrelated to bacteria in various genera including haemophilus and corynebacterium. electron microscopy and chemical analyses have elucidated the org ... | 1992 | 1498765 |
| mycoplasma hominis in women with bacterial vaginosis. | an association between m. hominis and bacterial vaginosis (bv) was looked for in total 205 women characterized as having bv. vaginal specimens from these patients were studied for the presence of amines, polymorphonuclear leukocytes, clue cells, and lactobacilli, and were also cultured to isolate gardnerella vaginalis, m. hominis, trichomonas vaginalis, candida albicans and anaerobes. g. vaginalis was found to be the most common isolate from 132 cases (64.3%). m. hominis was isolated from 90 cas ... | 1992 | 1506065 |
| prenatal microbiological risk factors associated with preterm birth. | 1992 | 1525111 | |
| diagnosis of bacterial vaginosis in a gynaecology clinic. | to estimate the prevalence of bacterial vaginosis in women referred to a gynaecology clinic, and to compare two methods of diagnosing bacterial vaginosis. | 1992 | 1547176 |
| sialidases (neuraminidases) in bacterial vaginosis and bacterial vaginosis-associated microflora. | bacterial vaginosis, prevotella species, and bacteroides species have been associated with prematurity and upper genital tract infection. prevotella (bacteroides) species and bacteroides fragilis have also been associated with preterm birth. however, the mechanism by which lower genital tract infection causes upper genital tract disease remains poorly understood. sialidases (neuraminidases) are enzymes which enhance the ability of microorganisms to invade and destroy tissue. elevated levels of s ... | 1992 | 1551983 |
| [prevalence of g. vaginalis, mycoplasma, ureaplasma, t. vaginalis, yeast, n. gonorrhoeae and other bacteria in women with vaginal discharge]. | vaginal discharge of 118 women attended to outdoor clinics of obstetrics and gynaecology at medical faculty of ankara university (a.u.t.f.), have been examined. direct microscopy has been made by means of wet mount, gram and giemsa staining. vaginal ph has been measured, by 10% koh the presence of "fishy odor" has been investigated. for culturing vaginal secretions in amies transport medium have been brought to microbiology department of ankara university, faculty of medicine inoculations have b ... | 1992 | 1588849 |
| comparison of the vaginal flora in sexually abused and nonabused girls. | the presence of sexually transmitted pathogens in the vagina of the sexually abused girl may provide direct evidence of sexual abuse; the presence of other abnormal vaginal organisms may provide indirect evidence of abuse. to identify abnormal vaginal organisms, we prospectively studied the flora of 209 sexually abused girls (cases) and compared it with that in a concurrent control group of 108 girls. case and control subjects were from the same community, were predominantly white, and 71% of ea ... | 1992 | 1593345 |
| report on gardnerella vaginitis. | gardnerella vaginitis is one of the most common diagnoses in our outpatient clinic. from january 1, 1989 through july 30, 1989 we had 230 positive cultures for g. vaginitis. eighty-three compliant patients in this group had unabated symptoms with documented positive cultures for gardnerella after treatment with metronidazole. this led to the use of alternative regimens of ceftriaxone or clindamycin. a survey of antibiotic choice and post-treatment culture obtained 103 entries from 34 active duty ... | 1992 | 1603376 |
| prenatal microbiological risk factors associated with preterm birth. | to study the vaginal flora of pregnant women at 22-28 weeks gestation to determine whether the presence of specific micro-organisms is significantly associated with preterm birth and prelabour rupture of the membranes. | 1992 | 1606115 |
| comparison of ofloxacin and metronidazole for the treatment of bacterial vaginosis. | the efficacy and safety of ofloxacin, 200 mg twice daily for 7 days, was compared with metronidazole, 400 mg twice daily for 7 days, for the treatment of bacterial vaginosis (bv). diagnosis of bv was confirmed by at least 3 of the following 4 criteria: the presence of an abnormal vaginal discharge on examination, clue cells on microscopy of vaginal specimens, vaginal ph greater than 5.0 and a positive amine test. vaginal specimens were examined for mobiluncus spp, analysed for the succinate/lact ... | 1992 | 1616967 |
| treatment for gardnerella vaginitis. | 1992 | 1620523 | |
| the effects of a combined contraceptive vaginal ring releasing ethinyloestradiol and 3-ketodesogestrel on vaginal flora. | fifty nine women with documented normal ovulatory cycles and with no symptoms of vaginal infection were divided into four groups. each group used a combined contraceptive vaginal ring (ccvr) with a mean daily release rate of 0.015 mg of ethinyloestradiol (ee) and 0.120 mg of 3-ketodesogestrel (3-kdg) per day, for one cycle of either 21, 28, 42, or 56 days. cultures from the posterior vaginal fornix and from the endocervical canal were obtained immediately before insertion of the ring and on remo ... | 1992 | 1623721 |
| involvement of gardnerella vaginalis in urinary tract infections in men. | fifteen male patients from whose urine samples gardnerella vaginalis was isolated (clinical incidence of 0.1%) were evaluated for clinical signs and symptoms of urinary tract infection and modality of acquisition of the organism. ten of 15 (67%) patients were symptomatic or had signs of inflammation as manifested by an increased number of urinary neutrophils. one patient had two bouts of infection caused by this organism which required two courses of antibiotic therapy. colonies of diphtheroidli ... | 1992 | 1624577 |
| the relationship of hydrogen peroxide-producing lactobacilli to bacterial vaginosis and genital microflora in pregnant women. | lactobacilli provide an important microbial defense against genital colonization by pathogens. the role of hydrogen peroxide (h2o2) in the control of genital microflora was explored in a cross-sectional study of 275 women in the second trimester of pregnancy. vaginal cultures were obtained for detection of h2o2-positive and h2o2-negative lactobacilli and other members of the genital microflora. compared with women with h2o2-negative lactobacilli, women colonized by h2o2-positive lactobacilli wer ... | 1992 | 1738516 |
| bacterial vaginosis associated with g vaginallis / mobiluncus sp: ultrastructural parameters. | physicians at the national institute of perinatology in mexico city, mexico used a carl-zeiss em 10c electron microscope to examine genital secretion samples from 10 pregnant women (15-38 weeks' gestation) who had been diagnosed with mobiluncus species and gardnerella vaginalis infections to illustrate the form and structure of bacteria responsible for bacterial vaginosis. they were concerned that these bacteria induce preterm labor and premature rupture of membranes (pl/prom). these bacteria ... | 1992 | 12317783 |
| isolation of gardnerella vaginalis from the genital tract of six mares. | 1992 | 17424118 | |
| antimicrobial susceptibilities of gardnerella vaginalis. | the in vitro susceptibilities of 93 clinical isolates of gardnerella vaginalis to 25 antimicrobial agents were determined by the agar dilution method. all isolates were susceptible to penicillin, ampicillin, erythromycin, clindamycin, chloramphenicol, and trimethoprim. activity was poor for vancomycin, ly146032, the cephalosporins, ciprofloxacin, and imipenem. some resistance was observed with tetracycline and minocycline. the mics of metronidazole paralleled those of tinidazole, with the hydrox ... | 1993 | 8109944 |
| comparative in-vitro activities of the new quinolone, bay y 3118, and ciprofloxacin, sparfloxacin, tosufloxacin, ci-960 and ci-990. | the in-vitro activity of the new quinolone, bay y 3118, was compared with that of ciprofloxacin, tosufloxacin, sparfloxacin, ci-960 and ci-990 against 1640 isolates belonging to 117 bacterial species. against members of the enterobacteriaceae, bay y 3118 was as active as ci-960 and ci-990, up to four-fold more active than ciprofloxacin and tosufloxacin and up to 16-fold more active than sparfloxacin. the majority of enterobacteriaceae which were resistant to ciprofloxacin (mics > or = 2 mg/l) we ... | 1993 | 7605398 |
| isolation of chlamydia trachomatis among women with symptoms of lower genital tract infection. | isolation of chlamydia trachomatis from the endocervix using cyclohexamide-treated mccoy cells were done in order to estimate the prevalence rate of its infection among gynecologic out patients who had symptoms and/or signs of lower genital tract infection. there were 498 patients from may 1989 to july 1990. eighty-six per cent of these patients were 25 years old or older. most of them (63%) were agricultural employees. ninety-three per cent were married and 78 per cent had less than or equal to ... | 1993 | 7964252 |
| pore-forming and haemolytic properties of the gardnerella vaginalis cytolysin. | the pleomorphic bacterium gardnerella vaginalis releases in the culture broth a haemolytic exotoxin (gvh) which is probably a virulence determinant of this unique bacterium, implicated in gynaecological and urological disorders. this 59 kda cytolysin was purified to homogeneity in just one chromatographic step directly from the culture supernatant, a final specific activity up to 1.9 x 10(6) hu mg-1 being obtained. the toxin-induced lesion on human erythrocytes results from the formation of a po ... | 1993 | 7934928 |
| [sexually transmitted diseases (stds) in a group of adolescents attending a perinatal care institute]. | to start an active sexual activity at an earlier age and with a larger number of partners, has arousen the frequency of sexually transmitted diseases (sts). the teenagers are a group particularly affected. the objective of this article is to report the etiology of std in a group of teenagers, out-patients at the instituto nacional de perinatologia (inper). the study includes 1360 patients at the clinic of std at the inper, 8.5 percent were less than 20 years old; 18.9 percent of them had previou ... | 1993 | 8063080 |
| [a trial of the use of diflucan (fluconazole) in patients with vaginal candidiasis]. | fifty females with vaginitis due to candida albicans were treated with fluconazol (diflucan) in a single dose of 150 mg administered per os. a complete elimination of the clinical signs in 42 out of 50 patients (84 per cent) and a significant improvement of the clinical picture in 4 out of 50 patients (8 per cent) were recorded. the cultures of the smears produced no fungal growth with respect to 31 out of 36 patients (86.1 per cent), while microscopically the presence of the fungus with the sig ... | 1993 | 8085908 |
| ionic factors regulating the interaction of gardnerella vaginalis hemolysin with red blood cells. | we have studied the hemolytic properties of an exotoxin released by gardnerella vaginalis (gvh). we found that hemolysis induced by gvh is modulated by the composition of the isotonic buffer in which the red cells are suspended. in particular, low ph enhances its lytic activity, whereas low ionic strength and divalent cations diminish it. the inhibitory effects of reduced salt concentration and divalent cations occur despite normal binding of the toxin to the cells. this suggests that some post- ... | 1993 | 8241250 |
| internal bacterial flora of solid uterine cervical cancer. | twenty-five patients with uterine cervical cancer (two cases stage o; four cases stage ia; five cases stage ib; one case stage iia; ten cases stage iib; two cases stage iiia; one case stage iva) served as the subjects. the bacterial flora inside the cervical cancers was investigated using the optimal technique. there was mixed abnormal aerobic and anaerobic bacterial flora in all subjects. the average number of bacterial species isolated from inside the cervical cancers was 6.3. the predominant ... | 1993 | 8270797 |
| treatment of post-cesarean section endometritis with ampicillin and sulbactam or clindamycin and gentamicin. | seventy-seven patients were prospectively enrolled in a randomized clinical trial to compare two antimicrobial regimens for the treatment of post-cesarean section endometritis. the two groups were not significantly different with respect to age, race, gravidity, parity, hours in labor, cesarean section indication, preoperative or postoperative hemoglobin/hematocrit, pretreatment white blood cell count or pretreatment temperature. pretreatment urine, blood and endometrial cultures were obtained. ... | 1993 | 8277478 |
| [vaginitis and vaginosis. comparison of two periods]. | vaginitis is the most frequent gynecological disease. it is characterized by objective and subjective signs of inflammation and differs from bacterial vaginosis (bv) which is an abnormal condition of the vaginal ecosystem caused by the excessive growth of aerobic and anaerobic flora normally present in the vagina with an increased risk of pelvic inflammatory disease (pid). the authors report the results of a study carried out at the centre for gynecological infections at the clinic of obstetrics ... | 1993 | 8278079 |
| [anaerobic bacteria and gynecologic infections]. | the normal vaginal flora consists of a wide variety of bacteria and the composition of this microflora is influenced by hormonal, metabolic and pharmacological factors. an increased concentration of a mixed anaerobic flora (mobiluncus, prevotellae, peptostreptococci and gardnerella vaginalis) appears to be an early stage in the development of bacterial vaginosis or in the infection of the upper genital tract. women with bacterial vaginosis are at increased risk of bartholinitis, skenitis, pelvic ... | 1993 | 8290794 |
| [prevalence of 4 agents of sexually transmitted diseases in leukorrhea in abidjan (ivory coast)]. | 6,603 women with vaginal discharges were investigated for genital infection with four sexually transmitted diseases. germs of vaginitis were isolated with prevalence as following: c. albicans 25%, g. vaginalis 17.4%, t. vaginalis 8.2%. cervicitis with n. gonorrhoeae represented 3.2% of cases. | 1993 | 8292912 |
| [gardnerella vaginalis in infections of reproductive organs]. | the study was aimed at multidirectional studies on bacteria isolated from smears from vagina and cervix uteri in 226 patients with inflammatory states of their reproductive organs. most frequently isolated aerobic bacteria were gram-negative--27%, mainly e. coli, and enterococcus faecalis--in 18% of cases. anaerobic bacteria were isolated in 81% of cases: gardnerella vaginalis was isolated in 28% and lactobacillus in 53% of cases. other anaerobic bacteria were: peptococcus asaccharolyticus (15.5 ... | 1993 | 8309297 |
| the normal vaginal flora, h2o2-producing lactobacilli, and bacterial vaginosis in pregnant women. | in this study of the vaginal flora of 171 pregnant women in labor at term, the flora was categorized as normal (lactobacillus predominant), intermediate, or representative of bacterial vaginosis (bv) on the basis of a vaginal smear. bv was diagnosed in 39 women (23%); the vaginal flora was classified as normal in 50% of cases and as intermediate in 27%. h2o2-producing lactobacilli were recovered from 5% of women with bv, 37% of those with an intermediate flora, and 61% of those with a normal flo ... | 1993 | 8324131 |
| the vagina as an ecologic system. current understanding and clinical applications. | recent advances in understanding the mechanisms of dominance of the healthful microecology by lactobacillus acidophilus through microbicidal enzyme systems has led to renewed interest in ecologic approaches to vaginal health maintenance and treatment of vaginosis and vaginitis. review of pertinent research suggests that due to inadequate adherence of lactobacilli from dairy sources, contaminants in commercial sources, and lack of evidence of effectiveness in sparse clinical trials, intravaginal ... | 1993 | 8331425 |
| the microbiology of bacterial vaginosis. | a group of microorganisms are present concurrently in high concentrations in the vaginas of women with bacterial vaginosis. the major members of the group are gardnerella vaginalis, anaerobic gram-negative rods belonging to the genera prevotella, porphyromonas and bacteroides, peptostreptococcus species, mycoplasma hominis, ureaplasma urealyticum, and often mobiluncus species. facultative species of lactobacillus are present in lower concentrations and are less prevalent in bacterial vaginosis t ... | 1993 | 8357043 |
| diagnostic microbiology of bacterial vaginosis. | bacterial vaginosis is characterized microbiologically by replacement of the lactobacillus-predominant vaginal flora by gardnerella vaginalis, bacteroides species, mobiluncus species, and genital mycoplasmas. a standardized, laboratory-based diagnostic test for bacterial vaginosis is desirable in those instances in which a microscope is unavailable in the clinic or when the evaluator of the wet mount examination is inexperienced at recognizing clue cells. vaginal cultures have excellent sensitiv ... | 1993 | 8357044 |
| chorioamnionitis and bacterial vaginosis. | an improved understanding of bacterial vaginosis and of clinical intraamniotic infection and histologic chorioamnionitis has produced data showing strong associations among these conditions. it has recently been shown that the microorganisms in both bacterial vaginosis and clinical intraamniotic infection are similar, of which anaerobes, gardnerella vaginalis, and mycoplasma hominis are the predominant organisms in both. furthermore, in the amniotic fluid of women with intraamniotic infection, s ... | 1993 | 8357045 |
| historical review of the treatment of bacterial vaginosis. | the review of the treatment of bacterial vaginosis parallels the history of this syndrome. before the syndrome was defined, treatment was local and nonspecific. gardner and dukes defined nonspecific vaginitis in 1955 as an infection caused by haemophilus vaginalis. therapy was directed toward this aerobic "pathogen" and included oral tetracycline and a triple sulfa vaginal cream. subsequent studies indicated success with this regimen as well as with ampicillin, a drug with good aerobic activity. ... | 1993 | 8357049 |
| in vitro antimicrobial activity of tioconazole and its concentrations in vaginal fluids following topical (vagistat-1 6.5%) application. | in vitro assays demonstrated that clinical yeasts were significantly more inhibited by tioconazole (mic50, < or = 0.5 microgram/ml) than by fluconazole (mic50, 8 micrograms/ml). tioconazole also exhibited high potency against most molds (alterneria spp. and acremonium spp.). all candida tropicalis isolates had mics of 8 micrograms/ml, four-fold greater than any other candida spp. generally gram-negative bacteria were less susceptible to tioconazole. moraxella catarrhalis (mic90, 2 micrograms/ml) ... | 1993 | 8359005 |
| [isolation of gardnerella vaginalis from vaginal discharge specimens]. | in this study specimens taken from 93 patients who admitted to outpatient clinics of ssk ankara gynaecology and obstetrics hospital with vaginal discharge were examined for g. vaginalis, t. vaginalis, c. albicans and n. gonorrhoeae. we evaluated the smell, ph, direct microscopic examinations, stained preparations and specific culture results of the discharges which were taken from posterior fornix. we isolated g. vaginalis from 13 patients (13.9%), t. vaginalis from 5 patients (5.3%) and c. albi ... | 1993 | 8361406 |
| [quantitative study of vaginal flora during the menstrual cycle]. | the aerobic and facultatively anaerobic vaginal flora of 242 healthy women were examined during menstrual cycles. the most frequently isolated microorganisms at the first premenstrual examination were coagulase-negative staphylococci (61%), followed by enterococci (25%), gardnerella vaginalis (19%), diphtheroids (12%), group b streptococci (6.8%), escherichia coli (5.4%) and candida spp. (4%). the isolation rate of all species, except candida and gardnerella vaginalis increased during menstruati ... | 1993 | 8375634 |
| antimicrobial activity and spectrum of rifaximin, a new topical rifamycin derivative. | rifaximin, a rifamycin derivative, was evaluated in vitro to assess its spectrum and potency against a wide variety of bacteria, yeasts, viruses, and parasites. high concentrations of rifaximin were often used to reflect topically achieved levels since this compound is poorly absorbed by oral route. like rifampin, rifaximin possessed best activity against staphylococcus spp. (mic50 < or = 0.015 microgram/ml), streptococcus spp. (mic50s, < or = 0.03-0.12 microgram/ml), enterococcus spp. (mic50s, ... | 1993 | 8385592 |
| phosphorylation and activation of the arachidonate-mobilizing phospholipase a2 in macrophages in response to bacteria. | the role of potential target enzymes in the protein-kinase-c-independent eicosanoid response triggered by certain bacteria in murine peritoneal macrophages [svensson, u., holst, e. & sundler, r. (1991) eur. j. biochem. 202, 699-705] has been investigated. the eicosanoid response was found to be due to an increase in the mobilization of arachidonate rather than to inhibition of arachidonate esterification or activation of the cyclooxygenase pathway and to be accompanied by a persistent increase i ... | 1993 | 8386632 |
| erythromycin versus metronidazole in the treatment of bacterial vaginosis. | of 101 women, 15-50 years of age, presenting with vaginal discharge, 34 had bacterial vaginosis and were randomly assigned to a seven-day course of oral treatment with either erythromycin (0.5 g b.i.d.) or metronidazole (0.4 g b.i.d.) in a single-blind, cross-over study. treatment failure (> or = three clinical signs of bacterial vaginosis) occurred in 13 (81%) of 16 patients given erythromycin, as compared with three (17%) of 18 women treated with metronidazole (p < 0.001). persistence of gardn ... | 1993 | 8394627 |
| perinatal effects of gardnerella vaginalis deciduitis in the rabbit. | we determined the effects of intrauterine infection with gardnerella vaginalis on maternal and fetal outcome in the rabbit. | 1993 | 8456914 |
| tumour necrosis factor alpha and interleukin 2 in normal and infected human seminal fluid. | the presence of cytokines such as the tumour necrosis factor alpha (tnf alpha) and interleukin 2 (il2) in human spermatozoa is still to be defined. the aim of this study was to measure the concentration of both soluble factors in seminal fluid. data from normal semen samples (n = 24) confirmed the presence of il2 (258 +/- 84 fmol/ml corresponding to 953 +/- 369 fmol/total volume of ejaculate) and tnf alpha (62.2 +/- 16.4 fmol/ml corresponding to 231.3 +/- 86 fmol/total volume of ejaculate). a si ... | 1993 | 8473457 |
| [how can reinfection by gardnerella vaginalis be prevented?]. | 1993 | 8479572 | |
| [the definition and epidemiology of bacterial vaginosis]. | bacterial vaginosis is a condition with a flora change in the vaginal where a lactobacilli-dominated flora is exchanged with an abundant complex flora dominated by strict and facultative anaerobic bacteria. the condition seldom occurs in prepubertal girls and post-menopausal women, suggesting an hormonal component in its etiology. recurrent episodes of bacterial vaginosis are frequent. three out of four criteria should be fulfilled for establishing the diagnosis of bacterial vaginosis, i.e., an ... | 1993 | 8484086 |
| [clinical and colposcopic aspects of bacterial vaginosis]. | bacterial vaginosis is characterized by an uniform, malodorous, white-grey discharge. the presenting symptom is generally the unpleasant smell of the vaginal discharge, particularly following the menses or intercourse. other functional signs, such as pruritus, dysuria and dyspareunia are rare. inflammatory signs are frequent, and can be revealed by colposcopy with the lugol test: this shows punctuate colpitis with small regular points corresponding histologically to an inflammatory focus in the ... | 1993 | 8484087 |
| [the bacteriologic diagnosis of bacterial vaginosis in an urban practice]. | the term "bacterial vaginosis" carries both bacteriologic and clinical connotations. indeed, it implies that the vagina is uninflamed (as shown by the absence of polymorphonuclear neutrophils), but that potential pathogens (particularly gardnerella vaginalis) are present. many studies conducted over the last 10 years have shown that a tentative diagnosis is simple to make, based on the sniff test, the aspect of the vaginal discharge, the presence of clue cells, and the absence of polymorphonucle ... | 1993 | 8484088 |
| [recent bacteriologic data: from physiopathology to treatment]. | bacterial vaginosis is characterized by a change in the vaginal ecosystem in which lactobacillus spp, the dominant members of the normal flora, are replaced by an association of various bacterial species including gardnerella vaginalis, anaerobes (bacteroides spp, prevotella spp, porphyromonas spp, peptostreptococcus spp and mobiluncus spp) and mycoplasma hominis. the reasons for this imbalance are unknown, although the loss of lactobacilli that produce hydrogen peroxide (which is toxic for g. v ... | 1993 | 8484089 |
| comparative susceptibility of the bacteroides fragilis group species and other anaerobic bacteria to meropenem, imipenem, piperacillin, cefoxitin, ampicillin/sulbactam, clindamycin and metronidazole. | the in-vitro activity of meropenem, imipenem, piperacillin, cefoxitin, ampicillin/sulbactam, clindamycin and metronidazole was determined against 395 strains of strict and facultative anaerobes, including gardnerella vaginalis, lactobacillus spp. and mobiluncus spp. the activities of meropenem and imipenem were within one dilution of their mic50 and mic90 values. one isolate of bacteroides fragilis, two of bacteroides distasonis, and two of bacteroides ovatus showed resistance or diminished susc ... | 1993 | 8486570 |
| efficacy of intravaginal 0.75% metronidazole gel for the treatment of bacterial vaginosis. | to assess the efficacy of 0.75% metronidazole vaginal gel, formulated at ph 4.0, for the treatment of bacterial vaginosis in a double-blind, placebo-controlled crossover trial. | 1993 | 8497364 |
| prevalence of cervical pathogens in women with and without inflammatory changes on smear testing. | to assess correlation between nonspecific cervicitis, inflammation, or exudate on cervical smears tests and confirmed presence of known cervical pathogens. | 1993 | 8499824 |
| in vitro activity of fk037, a new parenteral cephalosporin, against anaerobic bacteria. | the activity of fk037, a new parenteral cephalosporin, was compared with those of cefpirome, ceftazidime, and flomoxef against 322 recent clinical isolates of anaerobic bacteria. a fastidious facultative anaerobe, gardnerella vaginalis, was also studied. fk037 inhibited 90% of isolates of peptostreptococcus anaerobius, peptostreptococcus asaccharolyticus, clostridium perfringens, mobiluncus spp., g. vaginalis, and porphyromonas gingivalis at < or = 0.78 micrograms/ml. the mics of fk037 for 50 an ... | 1993 | 8517721 |
| carriage of gardnerella vaginalis in the urethra of indian men. | a total of 310 consecutive sexually active men attending sexually transmitted disease clinic of the nehru hospital, chandigarh, were studied to assess the prevalence of g vaginalis. non-gonococcal urethritis (ngu) was diagnosed in 53, acute gonococcal urethritis (agu) in 20, psychosomatic disorders in 50 and genital ulcer disease in 187 patients. g. vaginalis was isolated in 11 patients (3.5%) only. of these 11 isolates, 4(7.5%) were from patients with ngu, 2(10.0%) from men diagnosed to have ag ... | 1994 | 8088884 |
| changes in vaginal flora during pregnancy and association with preterm birth. | a prospective study of the vaginal flora changes between midtrimester and labor was undertaken in 560 women; 337 had intact membranes and were in labor when swabs were taken. of these, 45 delivered preterm. gardnerella vaginalis, ureaplasma urealyticum (both associated with preterm birth when present in midtrimester), and mycoplasma hominis commonly persisted between midtrimester and labor, particularly in the preterm cohort (24 [65%] of 37 midtrimester isolates), and these organisms were seldom ... | 1994 | 8077737 |
| variability of polymerase chain reaction-based detection of human papillomavirus dna is associated with the composition of vaginal microbial flora. | the results of repeated human papillomavirus (hpv) dna testing were compared to changes in cervical pathology and the composition of vaginal microorganisms. a cohort of 19 women with hpv cervical infections in the absence of cervical intraepithelial neoplasia at enrollment was reexamined on average at 7.3-month intervals over a 2-year period. at each follow-up visit, cytological and colposcopic examinations were done and vaginal microorganisms were assessed quantitatively by gram staining of sec ... | 1994 | 8083669 |
| [gardnerella vaginalis as urinary pathogen]. | to study the significance of gardnerella vaginalis in urine by comparing urine culture results, leucocytes count and clinical findings. | 1994 | 7948115 |
| expanded polytetrafluoroethylene patch versus braided polyester tape for the repair of incompetent cervix. | this study was done to evaluate pregnant patients with cervical incompetence using an expanded polytetrafluoroethylene (eptfe) patch versus the commonly used braided polyester tape, comparing the rate of local tissue reaction or onset of contractions, or both. | 1994 | 7952453 |
| study on treatment of bacterial vaginosis with oral administration of metronidazole or cefdinir. | bacterial vaginosis (bv) is considered to be one of the most common vaginal infections in women. fifteen symptomatic women with bv were enrolled in this study. ten patients with the diagnosis of bv were treated with 10 days oral administration of metronidazole (mtn), 500 mg twice a day, and five patients with cefdinir (cfdn), 300 mg three times a day. in the mtn therapy, the rate of abnormal vaginal discharge subjectively decreased from 100 to 60%, the rate of abnormal vaginal discharges objecti ... | 1994 | 7956461 |
| evaluation of api coryne system for identifying coryneform bacteria. | to identify rapidly and accurately coryneform bacteria, using a commercial strip system. | 1994 | 7962633 |
| [biocenosis of the vagina and infection with chlamydia trachomatis]. | the authors have examined 379 women for infection by chlamydia trachomatis, performing vaginal smears and routine bacterial cultures. c. trachomatis was discovered in 33.2% of the women, most frequently accompanied by erosion of the collum, cervicitis and cin-ca. women with c. trachomatis had the following levels of vaginal purity: 1-44.4%, 2-23.0%, 3 and 4-29.4%, 3.2% -leukocytes only. leukocytes were present in significantly more women with level 1 of vaginal purity than in the control group. ... | 1994 | 7967934 |
| patient education. diagnosis and treatment of bacterial vaginosis. | this paper continues our series looking at some of the information patients may require with regard to common health problems. providing information that is comprehensible is an important part of the nurse's role. it is vital that information, usually provided for particular specialties, is made available to all health-care workers and patients. | 1994 | 7971311 |
| [the use of eubiotics for the treatment of bacterial vaginosis]. | the study was concerned with the problem of the treatment of bacterial vaginosis. to correct the dysbiotic condition in the vagina, a two-stage procedure was applied. the first stage was aimed at the provision of the normal physiological condition of the vaginal medium and mucosa and the second stage was aimed at the provision of the normal microbiocenosis. at the second stage biological preparations such as lactobacterin, acylact, bifidumbacterin and bifidin were used. the recovery was stated i ... | 1994 | 7979792 |
| [vulvo-cervico-vaginal inflammatory pathologies in childhood and adolescence. our experience]. | one hundred and twenty-seven pediatric and adolescent patients suffering from vulvo-vaginitis underwent clinical and instrumental tests. the results of bacterioscopic and cultural test were negative in 39 (31.7%) patients due to the probable intervention of local hormonal, allergic and/or irritative factors. the tests used by the authors revealed phlogosis in 88 patients (68.3%) which was aspecific in 58 cases (65.9%) and specific in 30 (34.1%). while aspecific phlogosis were basically caused by ... | 1994 | 7984324 |
| sexually transmitted diseases in children: non viral including bacterial vaginosis, gardnerella vaginalis, mycoplasmas, trichomonas vaginalis, candida albicans, scabies and pubic lice. | 1994 | 8039788 | |
| [urethro-adnexitis in the man and acute urethral syndrome in the woman. microbiological and immunologic studies of etiologic classification]. | both common pathogens and unconventional, fastidious bacteria, viruses, parasites, and fungi are causative agents in male urethro-adnexitis and in female acute urethral syndrome. uropathogens, neisseria gonorrhoeae, treponema pallidum, mycobacterium tuberculosis, chlamydia trachomatis, mycoplasma spp., haemophilus ducreyi, calymmatobacterium granulomatis, gardnerella vaginalis, anaerobic bacteria, herpes simplex virus type ii (hsv ii), papillomaviruses (hpv), trichomonas vaginalis and candida sp ... | 1994 | 8053087 |
| bacteremia due to gardnerella vaginalis: report of two cases. | 1994 | 8054429 | |
| cytopathologic changes associated with intrauterine contraceptive devices. a review of cervico-vaginal smears in 350 women. | cervico-vaginal smears from 350 iucd users were analysed to ascertain the range of abnormalities induced in the genital tract of these women. alteration of the microbial environment, inflammatory, degenerative, reparative and proplastic epithelial changes were the salient cytological findings. the clinical implications of these are briefly discussed. | 1994 | 8057995 |
| bacterial vaginosis in pregnancy and efficacy of short-course oral metronidazole treatment: a randomized controlled trial. | to characterize the natural history of bacterial vaginosis in pregnancy and to assess the efficacy of short courses of oral metronidazole therapy for long-term suppression of bacterial vaginosis flora. | 1994 | 8058228 |
| microbiological patterns in vaginitis. | to determine the incidence and microbial aetiology of vaginitis, and the usefulness of gram staining of vaginal fluid in detecting the aetiology of vaginitis in sri lankan women. | 1994 | 7923459 |
| in vitro adhesiveness of gardnerella vaginalis strains in relation to the occurrence of clue cells in vaginal discharge. | g. vaginalis was isolated from 52.4 per cent patients with non-specific vaginitis. the haemagglutinating activity of g. vaginalis was strongest with human 'o' red cells and weaker reactions were observed with sheep and chick erythrocytes. haemagglutinating activity of g. vaginalis with human 'o' cells (1:16 titre) could be correlated with clue cells in vaginal discharge in 73 per cent patients while in lower titres, this correlation was not observed. | 1994 | 7927556 |
| a wet smear criterion for bacterial vaginosis. | to evaluate a simpler criterion for bacterial vaginosis than the recommended criterion of amsel. | 1994 | 7863139 |
| effects of cetyltrimethylammonium naproxenate on the adherence of gardnerella vaginalis, mobiluncus curtisii, and lactobacillus acidophilus to vaginal epithelial cells. | a decreased concentration or total disappearance of lactobacillus acidophilus in the vagina constitutes a frequent observation in bacterial vaginosis. | 1994 | 7871448 |
| [bacterial vaginosis. prevention of recurrence]. | bacterial vaginosis (bv) is the main cause of vaginitis. the condition is characterised by an abundant and odorous vaginal loss, but more than half the patients with demonstrable signs of bv do not report symptoms at all. gardnerella vaginalis (gv) is often associated with bv, but it is not the sole factor responsible, as is shown by the fact that it can be isolated in the vagina of women withbv. in 1992 and 1993, 2630 patients, 1460 of them gynaecological and 1170 obstetric, were admitted to th ... | 1994 | 7885610 |
| bacterial vaginosis: drugs versus alternative treatment. | bacterial vaginosis is one of the most common infectious disorders affecting women. it is caused by several microorganisms, including gardnerella vaginalis, bacteroides, beta-streptococci and mobiluncus/falcivibrio sp. bacterial vaginosis is thought to occur as a result of a change in vaginal ph mediated by the metabolic activity of anaerobic bacteria. this rise in vaginal ph interferes with the activity of vaginal lactobacilli which maintain vaginal acidity. several types of antibiotics have be ... | 1994 | 7885656 |
| [genital microbial flora in a population of high obstetrical risk]. | there is increasing evidence showing the association between maternal genital infection, prematurity and neonatal or maternal morbidity. to know the genital flora of women attending a high risk pregnancy service, 73 consecutive pregnant women attending the high risk pregnancy service at the hospital san borja-arriarán from may to august 1992 were included in this study, 75.3% of the vaginal discharges corresponded to fluids of normal appearance and 24.7% were altered. the microorganisms most fre ... | 1994 | 7809430 |
| recurrent bacterial vaginosis unresponsive to metronidazole: successful treatment with oral clindamycin. | 1994 | 7810359 | |
| genital flora in pregnancy and its association with intrauterine growth retardation. | a study of risk factors for intrauterine growth retardation (iugr) was conducted among a cohort of 13,914 pregnant women enrolled in the multicenter vaginal infections and prematurity study. from 23 through 26 weeks of gestational age, cultures of specimens from the vagina and cervix were done for group b streptococci, neisseria gonorrhoeae, chlamydia trachomatis, trichomonas vaginalis, candida albicans, gardnerella vaginalis, mycoplasma hominis, ureaplasma urealyticum, and anaerobic gram-negati ... | 1994 | 7814541 |
| [value of the score for gram strains in the diagnosis of bacterial vaginosis]. | the interpretation of gram-stained slides of vaginal swab specimens is evaluated for the diagnosis of bacterial vaginosis and correlated with the isolation bacteria and clinical signs: thin homogeneous vaginal discharge, ph > or = 4.7, amine odor and presence of clue cells. gram stained smears were scored following a morphotype classification: (a)-lactobacillus morphotypes (scored 4 to 0), (b)-small gram negative (g. vaginalis, scored 0 to 4), (c)-curved gram variable rods (mobiluncus morphotype ... | 1994 | 7824329 |
| transhymenal cultures for sexually transmissible organisms. | vaginal swabs were examined for sexually transmissible organisms in 238 girls seen over a 36 month period from july 1989 to june 1992 inclusive. three groups were seen (age range 1.5-16.1 years), 165 in group 1 in whom there had been a disclosure of sexual abuse, 35 in group 2 where there was a strong suspicion of sexual abuse, and 38 with vulvovaginitis who formed group 3. the isolation of recognised sexually transmitted organisms was low; however, of group 1 19% were colonised with gardnerella ... | 1994 | 7826112 |
| a longitudinal study of bacterial vaginosis during pregnancy. | to determine the longitudinal changes in the incidence of vaginosis in pregnancy. | 1994 | 7826957 |
| sexually transmitted diseases. | 1994 | 7838609 | |
| prevalence of vaginitis, syphilis and hiv infection in women in the orange free state. | to determine the prevalence of vaginitis, syphilis and hiv infection in women in the orange free state. | 1994 | 7839281 |
| bacterial vaginosis in a district genitourinary medicine department: significance of vaginal microbiology and anaerobes. | the aim of this study was to correlate the significance of vaginal microbiology, in particular its anaerobic component, to the presence of bacterial vaginosis (bv), and to review the clinical criteria used in the diagnosis of this condition. ninety-two female patients who received routine std screening were studied. after routine history, presence and character of vaginal discharge and vaginal ph were noted, an amine test performed, and a wet stain observed microscopically. routine gram stain sm ... | 1994 | 7849117 |