Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| prevention of maternal bacterial transmission on children's dental-caries-development: 4-year results of a pilot study in a rural-child population. | dental caries with its bacterial agent is an infectious disease, and shows a vertical transmission. the control of bacterial transmission of mutans streptococci (ms) from mother to child has been studied, and its results on their children's caries development, and on their siblings' bacterial levels, have been analysed in a field-trial (for 4 years) in rural area. | 2007 | 17321488 |
| a modern paradigm for caries management, part 1: diagnosis and treatment. | 2007 | 17348283 | |
| effects of antibodies against a fusion protein consisting of parts of cell surface protein antigen and glucosyltransferase of streptococcus sobrinus on cell adhesion of mutans streptococci. | the cell surface protein antigen (pag) and glucosyltransferases (gtfs) produced by streptococcus sobrinus are considered to be major colonization factors of the organism. | 2008 | 18173793 |
| effect of ozone treatment on different cariogenic microorganisms in vitro. | ozone treatment has been presented and discussed in the literature, as one of the "new" ways to treat dental caries. the aim of this paper was to study the in vitro effect of ozone on some common oral microorganisms related to dental caries using scanning electron microscopy (sem). the effect of ozone was tested on three different strains of mutans streptococci and one lactobacillus strain. after exposure of bacteria to ozone treatment for 0 to 60 sec, cultivation on different chair side strips ... | 2008 | 18973084 |
| mathematical description, optimization and prediction of synergistic interaction of fluoride and xylitol. | the potential ability of various physical or chemical agents to enhance their effect when they are applied simultaneously with each other is well-known. the purpose of this study was to adjust a simple mathematical model to describe, optimize and predict a synergistic interaction between fluoride and xylitol on acid production by mutans streptococci. the model suggests that the synergism is caused by the additional effective damage arising from an interaction of sublesions induced by each agent. ... | 2008 | 18367232 |
| distribution of streptococcus mutans and streptococcus sobrinus in saliva of mexican preschool caries-free and caries-active children by microbial and molecular (pcr) assays. | the aim of the study was to investigate the distribution of mutans streptococci (ms) infection of caries-free (cf) and caries-active (ca) preschool mexican children by microbial and molecular assays. eighty preschool children were divided into two groups, 40 cf and 40 ca children. saliva samples were inoculated onto msb to identify cfu and dna extractions were tested by pcr. our results indicated that there was no statistical difference (p > 0.05) between groups either in age, weight, height or ... | 2008 | 18389677 |
| role of sucrose in the fitness of streptococcus mutans. | dental caries has been closely linked to fermentable carbohydrates as key environmental factors. sucrose has been identified as the most cariogenic carbohydrate. streptococcus mutans, considered to be the primary pathogen causing dental caries, is able to utilize sucrose as a nutrient source, partially for the production of intracellular storage components and for the production of extracellular glucans via the glucosyltransferases gtfb, gtfc, and gtfd. the following study explores the competiti ... | 2008 | 18402607 |
| [effects of oral streptococci on biofilm formation by cariogenic bacteria in dual species cultures]. | the effects of oral commensal streptococci (streptococcus sanguinis, streptococcus gordonii, streptococcus mitis, and streptococcus salivarius) on biofilm formation by cariogenic mutans streptococci (streptococcus mutans and streptococcus sobrinus) were investigated. cell suspensions were cultured on 96-well microtiter plates coated with or without salivary components (sc), and in flow cell systems coated with sc in tryptic soy broth including 0.25% sucrose without dextrose (tsb). the resultant ... | 2008 | 18421950 |
| impact of growth conditions on susceptibility of five microbial species to alkaline stress. | the effects of different growth conditions on the susceptibility of five taxa to alkaline stress were investigated. enterococcus faecalis atcc 29212, streptococcus sobrinus omz 176, candida albicans atcc 90028, actinomyces naeslundii atcc 12104, and fusobacterium nucleatum atcc 10953 were grown as planktonic cells, allowed to adhere to dentin for 24 hours, grown as monospecies or multispecies biofilms on dentin under anaerobic conditions with a serum-enriched nutrient supply at 37 degrees c for ... | 2008 | 18436038 |
| antimicrobial effect and ph of chlorhexidine gel and calcium hydroxide alone and associated with other materials. | the purposes of this study were to evaluate the effectiveness of 2% chlorhexidine (chx) gluconate gel, calcium hydroxide [ca(oh)2] and their combination with iodoform and zinc oxide powder as intracanal medications against select microorganisms, and to measure the ph changes caused by these medications. antimicrobial activity was determined by the agar diffusion method. the zones of growth inhibition were measured and the results were analyzed statistically by kruskal-wallis test (p<0.05). the p ... | 2008 | 18438556 |
| adhesion of oral streptococci to all-ceramics dental restorative materials in vitro. | in recent years, patients have benefited from the development of better and more esthetic materials, including all-ceramics dental restorative materials. dental plaque formation on teeth and restorative materials plays an important role in the pathogenesis of oral diseases. this study investigates initial adhesion of stationary phase streptococcal species to different all-ceramics dental restorative materials. the saliva-coated materials were incubated with the bacteria for 1 h in an in vitro fl ... | 2008 | 18470704 |
| a quantitative approach to the effectiveness of ozone against microbiota organisms colonizing toothbrushes. | toothbrushes are rapidly contaminated with different microorganisms, which colonize the oral cavity and interdental spaces. this can represent a possible cause of infection or reinfection. in this study, the ozone experimental effect upon toothbrushes microflora was estimated microbiologically before and after saturation with ozone gas. | 2008 | 18502558 |
| quantitative analysis of adhesion of cariogenic streptococci to orthodontic raw materials. | knowledge of adhesion patterns of cariogenic streptococci to orthodontic materials can provide valuable information on the cause of enamel demineralization during orthodontic treatment. the purpose of this study was to investigate the adhesion of 2 cariogenic streptococci strains to 7 orthodontic raw materials (3 light-cured orthodontic adhesives, 3 bracket raw materials, and hydroxyapatite) with respect to bacterial species, incubation time, and saliva coating. | 2008 | 18538253 |
| sequence and phylogenetic analyses of novel glucosyltransferase genes of mutans streptococci isolated from pig oral cavity. | nucleotide sequences of water-insoluble glucan-producing glucosyltransferase (gtf) genes of new mutans streptococci isolated from pig oral cavity, streptococcus orisuis jcm14035, and of streptococcus criceti hs-6 were determined. the gtf gene of s. orisuis jcm14035 consisted of a 4,401 bp orf encoding for a 1,466 amino acids, and was revealed to belong to the gtfi group. the percent homology of amino acid sequence of the gtf-i from s. orisuis and s. criceti are 95.0%, however, this score ranges ... | 2008 | 18545970 |
| [inhibitive effect of extracts of galla chinesis on caries development in rats]. | to evaluate the inhibitive effect of galla chinesis extract (gce) and gce-b on dental caries formation and plaque microbiology in rats. | 2008 | 18575346 |
| antimicrobial activity of kaurane diterpenes against oral pathogens. | two kaurane diterpenes, ent-kaur-16(17)-en-19-oic acid (ka) and 15-beta-isovaleryloxy-ent-kaur-16(17)-en-19-oic acid (ka-ival), isolated from aspilia foliacea, and the methyl ester derivative of ka (ka-me) were evaluated against oral pathogens. ka was the most active compound, with mic values of 10 microg ml(-1) against the following microorganisms: streptococcus sobrinus, streptococcus mutans, streptococcus mitis, streptococcus sanguinis, and lactobacillus casei. however, ka did not show signif ... | 2008 | 18669015 |
| differences of the oral colonization by streptococcus of the mutans group in children and adolescents with down syndrome, mental retardation and normal controls. | to compare the concentration and serotype of streptococcus mutans in saliva of down syndrome (ds), mental retarded (mr) and healthy control (c) individuals of the región metropolitana sur of santiago of chile. | 2008 | 18758394 |
| effect of antiplaque compounds and mouthrinses on the activity of glucosyltransferases from streptococcus sobrinus and insoluble glucan production. | the development of therapeutic agents inhibiting the activity of glucosyltransferases (gtf) and their production of glucans is a potential strategy to reduce dental decay. the aim of this study was first to characterize a gtf preparation from streptococcus sobrinus atcc 33478 and then to evaluate the effects of select compounds and mouthrinses on insoluble glucan (isg) formation by combined gtfs. | 2008 | 18793362 |
| influence of a chitosan on oral bacterial adhesion and growth in vitro. | generally, mechanical plaque control without chemical support is insufficient to prevent oral diseases, and an ongoing quest exists for new antimicrobials for use in oral healthcare. chitosans are polycationic, naturally occurring antimicrobials that are rapidly finding their way into oral healthcare. in this study we determined the effects of pellicle treatment with chitosan on bacterial adhesion and growth. chitosan caused a reduction in bacterial adhesion and was responsible for bacterial dea ... | 2008 | 18821994 |
| xylitol gummy bears reduce plaque in young children. | 2008 | 18832266 | |
| streptococcus mutans and streptococcus sanguinis colonization correlated with caries experience in children. | the aim of this study was to examine the colonization of streptococcus mutans and streptococcus sanguinis in the oral cavity and the association with severe early childhood caries (s-ecc). saliva and plaque samples were collected from 14 s-ecc children and 8 caries-free (cf) children. all s-ecc children were s. mutans positive; 100% of cf children and 93% of s-ecc children were s. sanguinis positive. the children's caries severity was positively correlated with levels of s. mutans (p < 0.001), t ... | 2008 | 18832831 |
| streptococcus cristatus attenuates fusobacterium nucleatum-induced interleukin-8 expression in oral epithelial cells. | oral epithelial cells may be invaded by a polymicrobial intracellular flora, including pathogens together with commensals. various oral pathogens can induce the production of interleukin-8, a potent neutrophil chemotractant, in oral epithelial cells. evidence from the gut suggests that commensal species may modulate inflammatory responses to pathogens. the aim of this study was to examine the interleukin-8 responses of oral epithelial cells to an oral pro-inflammatory species, fusobacterium nucl ... | 2008 | 18942189 |
| effect of xylitol on an in vitro model of oral biofilm. | the aim of the present study was to examine whether xylitol, at different concentrations, inhibits the formation of an experimental model of oral biofilm. | 2008 | 19178100 |
| effects of amine fluoride on biofilm growth and salivary pellicles. | the amine fluoride (amf) n'-octadecyl-trimethylene-diamine-n,n,n'-tris(2-ethanol)-dihydro-fluoride is a cationic antimicrobial which can have beneficial effects on plaque formation. here, we determine changes in pellicle and bacterial cell surface properties of the strains actinomyces naeslundii hm1, streptococcus mutans ns, s.mutans atcc 700610, s. sobrinus hg1025 and s. oralis hm1 upon adsorption of this amf and accompanying effects on bacterial adhesion and biofilm growth. in vitro pellicles ... | 2008 | 18042986 |
| inhibitory effect of cranberry polyphenol on cariogenic bacteria. | the purpose of this study was to investigate the effect of cranberry polyphenol fraction on mutans streptococci. hydrophobicity is an important factor in the adherence of bacteria to the tooth surface. we found that cranberry polyphenol fraction significantly decreased the hydrophobicity of streptococcus sobrinus 6715, streptococcus mutans mt8148r and jc2 in a dose-dependent manner (p<0.05). biofilm formation by s. sobrinus 6715 and s. mutans mt8148r was inhibited by 100 microg/ml cranberry poly ... | 2008 | 19129685 |
| effects of alpha-amylase and its inhibitors on acid production from cooked starch by oral streptococci. | this study evaluated acid production from cooked starch by streptococcus mutans, streptococcus sobrinus, streptococcus sanguinis and streptococcus mitis, and the effects of alpha-amylase inhibitors (maltotriitol and acarbose) and xylitol on acid production. streptococcal cell suspensions were anaerobically incubated with various carbohydrates that included cooked potato starch in the presence or absence of alpha-amylase. subsequently, the fall in ph and the acid production rate at ph 7.0 were me ... | 2009 | 19136828 |
| in vitro antibacterial and cytotoxicity assessments of an orthodontic bonding agent containing benzalkonium chloride. | to assess the antibacterial activity and cytotoxicity of an orthodontic bonding material containing an antibacterial agent. | 2009 | 19216609 |
| bacterial profiles of oral streptococcal and periodontal bacterial species in saliva specimens from japanese subjects. | recent developments in molecular biological techniques have increased understanding of the distribution of oral bacterial species in clinical specimens, though few investigations have been conducted to simultaneously detect oral streptococcal and periodontal species in the same specimens. the purpose of the present study was to investigate the distribution and correlation of 6 oral streptococcal and 6 periodontal species in saliva specimens taken from children and their mothers. | 2009 | 19230860 |
| use of checkerboard dna-dna hybridization to evaluate the internal contamination of dental implants and comparison of bacterial leakage with cast or pre-machined abutments. | to evaluate the checkerboard dna-dna hybridization method for detection and quantitation of bacteria from the internal parts of dental implants and to compare bacterial leakage from implants connected either to cast or to pre-machined abutments. | 2009 | 19250244 |
| quantitative real-time polymerase chain reaction for streptococcus mutans and streptococcus sobrinus in dental plaque samples and its association with early childhood caries. | streptococcus mutans and streptococcus sobrinus are closely associated with the development of early childhood caries (ecc). recently, quantitative real-time polymerase chain reaction (qrt-pcr) has been used for rapid and accurate quantification of these bacterial species. | 2009 | 19250396 |
| human milk compounds inhibiting adhesion of mutans streptococci to host ligand-coated hydroxyapatite in vitro. | acquisition of mutans streptococci at an early age is a risk factor for later caries development. following our recent finding that human milk may inhibit adhesion of streptococcus mutans the aim of the present study was to identify compounds in human milk preventing adhesion of mutans streptococci to saliva- or gp340-coated hydroxyapatite (s-ha and gp340-ha) using an in vitro model system. superdex 200 fractions of human milk and purified proteins were screened for binding inhibition of the s. ... | 2009 | 19390191 |
| final ph affects the interference capacity of naturally occurring oral lactobacillus strains against mutans streptococci. | to establish the effects of three factors: previous caries experience; colonization of streptococcus mutans; and final ph on autologous lactobacilli-mediated inhibition against a panel of mutans streptococci in young subjects with different caries experiences. | 2009 | 19394588 |
| multi-species biofilm formation on dental materials and an adhesive patch. | this laboratory study assessed the influence of surface roughness and contact time on the formation of a multi-species biofilm on dental materials (adhesive patch, composite, amalgam and enamel). | 2009 | 19408815 |
| does strontium play a role in the cariostatic activity of glass ionomer? strontium diffusion and antibacterial activity. | the aim of this work was to evaluate the activity of strontium ions on the main pathogens of the oral flora. the leaching of strontium from resin modified glass ionomer cements (rmgic) was evaluated together with its uptake by superficial dental enamel. | 2009 | 19410352 |
| molecular and biological characterization of gtf regulation-associated genes in streptococcus mutans. | surface protein antigen (pac) and glucosyltransferases (gtf) are major adhesive molecules of streptococcus mutans, though the mechanism of their regulation has not been fully elucidated. | 2009 | 19416450 |
| genes responsible for dextran-dependent aggregation of streptococcus sobrinus strain 6715. | streptococcus sobrinus exhibits more significant dextran-dependent aggregation mediated by glucan-binding proteins than streptococcus mutans. we have identified four glucan-binding protein c gene (gbpc) homologues designated as gbpc1, gbpc2, dbla and dblb in s. sobrinus in contrast to the single gene gbpc in s. mutans. we attempted to determine which gene is most responsible for the dextran-dependent aggregation of s. sobrinus. | 2009 | 19416452 |
| pulmonary valve endocarditis in a pregnant woman with a ventricular septal defect. | bacterial endocarditis in pregnancy causes maternal and fetal mortality rates of 22.1% and 14.7%, respectively. the mortality rates differ according to the involved valves, and the size of vegetation has a prognostic correlation. this report is of a pregnant woman with an unrepaired ventricular septal defect and pulmonary valve endocarditis with a vegetation size of 3.29 cm. she and her baby were treated successfully. an emergency surgical plan would be appropriate for pregnant women in the thir ... | 2009 | 19424564 |
| inhibitory effects of partially decomposed alginate on production of glucan and organic acid by streptococcus sobrinus 6715. | our previous study has already clarified that partially decomposed alginate (alg53) by vibrio alginolyticus sun53 has a competitive inhibitory effect on sucrase. the objective of this study is to evaluate the influence of alg53 on the production of glucan from sucrose by glucosyltransferase and acid from glucose by streptococcus sobrinus 6715. glucosyltransferase was prepared from cultural medium of s. sobrinus using ultrafiltration and hydroxyapatite chromatography. in order to examine the inhi ... | 2009 | 19430617 |
| acidogenic potential of "sugar-free" cough drops. | a patient presented with extensive marginal ditching around restorations recently placed during whole-mouth rehabilitation. the patient was not xerostomic and was otherwise normal except for the self-reported excessive use of "sugar-free" cough drops sweetened with sorbitol and isomalt(r) (an equimolar mix of glucosyl-mannitol and glucosylsorbitol). this prompted an in vitro investigation to determine whether streptococcus sobrinus 6715, a cariogenic streptococcus, could grow and produce acid in ... | 2009 | 19444340 |
| construction of a new fusion anti-caries dna vaccine. | mutans streptococci (ms) are generally considered to be the principal etiological agent of dental caries. ms have two important virulence factors: cell- surface protein pac and glucosyltransferases (gtfs). gtfs have two functional domains: an n-terminal catalytic sucrose-binding domain (cat) and a c-terminal glucan-binding domain (glu). a fusion anti-caries dna vaccine, pgja-p/vax, encoding two important antigenic domains, pac and glu, of s. mutans, was successful in reducing the levels of denta ... | 2009 | 19493890 |
| identification of a bioactive compound isolated from brazilian propolis type 6. | a prenylated benzophenone, hyperibone a, was isolated from the hexane fraction of brazilian propolis type 6. its structure was determined by spectral analysis including 2d nmr. this compound exhibited cytotoxic activity against hela tumor cells (ic(50)=0.1756microm), strong antimicrobial activity (mic range-0.73-6.6microg/ml; mbc range-2.92-106microg/ml) against streptococcus mutans, streptococcus sobrinus, streptococcus oralis, staphylococcus aureus, and actinomyces naeslundii, and the results ... | 2009 | 19497755 |
| relationship of quantitative salivary levels of streptococcus mutans and s. sobrinus in mothers to caries status and colonization of mutans streptococci in plaque in their 2.5-year-old children. | the aim of this study was to assess the relationships of quantitative salivary levels of streptococcus mutans and s. sobrinus in mothers with the colonization of mutans streptococci (ms) in plaque and caries status in their 2.5-year-old children. furthermore, the dynamics of caries status in the children was evaluated in a 2-year follow-up survey. | 2009 | 19508271 |
| clinical and microbiological performance of resin-modified glass-ionomer liners after incomplete dentine caries removal. | the aims of this study were to evaluate clinically and microbiologically the effects of two resin-modified glass-ionomer cements (rmgics) used as liners after incomplete dentine caries removal and to identify streptococcus mutans and streptococcus sobrinus strains isolated from dentine samples, before and after indirect pulp treatment. twenty-seven primary molars with deep carious lesions, but without signs and symptoms of irreversible pulpitis, were submitted to indirect pulp treatment. treatme ... | 2009 | 19548010 |
| xylitol: effects on the acquisition of cariogenic species in infants. | the purpose of this study was to examine the effects of xylitol gum (xg) on the acquisition pattern of 39 bacterial species, including mutans streptococci (ms), in infants. | 2009 | 19552232 |
| transient acid-impairment of growth ability of oral streptococcus, actinomyces, and lactobacillus: a possible ecological determinant in dental plaque. | dental plaque ph decreases to about 4 through bacterial fermentation of carbohydrates and this low ph is maintained for from several minutes to about an hour. repeated acidification causes demineralization of the tooth surface, resulting in caries formation. the acidification also influences plaque bacteria. severe acidification kills bacteria efficiently, while physiological acidification, the condition occurring in plaque, kills bacteria partially and may impair growth ability. we, therefore, ... | 2009 | 19572895 |
| culture-based pcr analysis of plaque samples of japanese school children to assess the presence of six common cariogenic bacteria and its association with caries risk. | the aim of the study was to assess the presence of six common cariogenic bacteria from cariostat-inoculated plaque samples of japanese elementary school children through pcr analysis and check its associations with caries risk testing the validity of cariostat as a caries risk assessment tool. this epidemiological school-based study investigated plaque samples of 399 japanese elementary school children. assessed using the cariostat, 48.2% of the children had high caries risk. dna detection of st ... | 2009 | 19573592 |
| frequency and distribution of mutans streptococci in dental plaque from caries-free and caries-affected venezuelan children. | mutans streptococci, in particular s. mutans and s. sobrinus, are generally considered to be the prime etiological bacteria of human dental caries. the aim of this study was to determine the frequency of mutans streptococci in dental plaque in three groups of caries-free and caries-affected venezuelan children aged 2-6, 7-12, 13-19 years, and their possible association with dental caries. the frequency of mutans streptococci was determined in samples of pooled dental plaque collected from all de ... | 2009 | 19601491 |
| oral therapeutic vaccination with streptococcus sobrinus recombinant enolase confers protection against dental caries in rats. | dental caries is among the more prevalent chronic human infections for which an effective human vaccine has not yet been achieved. enolase from streptococcus sobrinus has been identified as an immunomodulatory protein. in the present study, we used s. sobrinus recombinant enolase (renolase) as a target antigen and assessed its therapeutic effect in a rat model of dental caries. wistar rats that were fed a cariogenic solid diet on day 18 after birth were orally infected with s. sobrinus on day 19 ... | 2009 | 18956975 |
| cariogenic potential of cows', human and infant formula milks and effect of fluoride supplementation. | the aim of the present study was to evaluate the cariogenicity of cows', human and infant formula milks, supplemented or not with fluoride, in rats. sixty female wistar rats were desalivated and infected with streptococcus sobrinus 6715.animals were divided into six groups: group 1, sterilised deionised distilled water (sdw; negative control); group 2, 5 % sucrose added to sdw (positive control); group 3, human milk; group 4, cows' milk; group 5, ninho(r) formula reconstituted with sdw; group 6, ... | 2009 | 18577299 |
| experimental antimicrobial orthodontic adhesives using nanofillers and silver nanoparticles. | experimental composite adhesives (ecas) containing silica nanofillers and silver nanoparticles were compared with two conventional adhesives (composite and resin-modified glass ionomer [rmgi]) to analyze surface characteristics, physical properties and antibacterial activities against cariogenic streptococci. | 2009 | 18632145 |
| identification and characterization of an autolysin gene, atlg, from streptococcus sobrinus. | atla is a major cell-lytic enzyme called autolysin in streptococcus mutans. in this study, we identified the atlg gene-encoding autolysin (atlg), consisting of 863 residues from streptococcus sobrinus 6715dp, and confirmed lytic activity of recombinant atlg by zymography of s. sobrinus cells. an atla-inactivated mutant was constructed in s. mutans xc, and the atlg gene product was characterized by plasmid complementation. microscopic analysis, saliva-induced aggregation assay and autolysis assay ... | 2009 | 19054069 |
| distribution, regulation and role of the agmatine deiminase system in mutans streptococci. | the agmatine deiminase system (agds) was identified in seven strains of mutans streptococci. genes encoding the agds of streptococcus rattus fa-1 were sequenced and found to share homology with the agu genes of streptococcus mutans ua159. with the exception of streptococcus sobrinus, the agds of mutans streptococci appear to be sensitive to carbohydrate catabolite repression. agmatine inhibited bacterial growth, suggesting that the agds degrades a deleterious substance into useful compounds. | 2009 | 19121075 |
| in vitro antimicrobial effect of bacteriocin psvp-10 in combination with chlorhexidine and triclosan against streptococcus mutans and streptococcus sobrinus strains. | to determine the minimal inhibitory concentrations (mics) of bacteriocin psvp-10, chlorhexidine and triclosan on s. mutans and s. sobrinus and to study the potential synergistic combination between these antimicrobial and the bacteriocin psvp-10. | 2009 | 19124118 |
| oral bacterial adhesion forces to biomaterial surfaces constituting the bracket-adhesive-enamel junction in orthodontic treatment. | bacterial adhesion to biomaterial surfaces constituting the bracket-adhesive-enamel junction represents a growing problem in orthodontics, because bacteria can adversely affect treatment by causing demineralization of the enamel surface around the brackets. it is important to know the forces with which bacteria adhere to the surfaces of these junction materials, as the strength of these forces will determine how easy it will be to remove the bacteria. we compared the adhesion forces of five init ... | 2009 | 19627354 |
| oral streptococcus species in pre-term and full-term children - a longitudinal study. | despite high clinical significance, the microbiology of the dental biofilm in young children remains poorly understood. | 2009 | 19732193 |
| poisson analysis of streptococcal bond-strengthening on saliva-coated enamel. | the forces responsible for bond-strengthening in initial oral bacterial adhesion are unknown. since lifshitz-van der waals and electrostatic forces work instantaneously upon approach, it is hypothesized that bond-strengthening is governed by hydrogen bonding. poisson analysis of adhesion forces observed during the retraction of bacterial probes from surfaces in atomic force microscopy can be used to analyze the nature of the adhesion forces. streptococcal adhesion forces increased from about -0. ... | 2009 | 19767582 |
| inhibiting effects of enterococcus faecium non-biofilm strain on streptococcus mutans biofilm formation. | enterococcus faecium is a normal bowel commensal and lactic acid bacterium that is rarely found in the oral cavity. this study investigated whether a non-pathogenic and non-biofilm strain of e. faecium functioned as a probiotic strain toward biofilm formation by streptococcus mutans, which is an etiological agent for dental caries. | 2009 | 19812852 |
| automutanolysin disrupts clinical isolates of cariogenic streptococci in biofilms and planktonic cells. | dental caries remains one of the most common chronic infectious diseases throughout the world. the formation of dental plaque is one of the caries risk factors. as a consequence, the removal of plaque may reduce the incidence of caries development. we identified an autolysin produced by streptococcus mutans named auto-mutanolysin (aml). aml selectively lyses s. mutans and streptococcus sobrinus. the specificity towards these cariogenic bacteria suggests that aml may be used to prevent dental car ... | 2009 | 19832796 |
| [discrimination of common oral streptococcus with metabonomics method]. | to evaluate the feasibility of identifying oral streptococcus by comparing their metabolic profiling, and to find a convenient and rapid way to discriminate oral microorganisms. | 2009 | 19927732 |
| [genotypic diversity of streptococcus sobrinus in 3 to 4-year-old children suffering with severe early childhood caries]. | to evaluate the genotypic diversity of streptococcus sobrinus (ss) between children suffering with severe early childhood caries (s-ecc) and caries-free children by arbitrarily primed-polymerase chain reaction (ap-pcr). | 2009 | 19953953 |
| [protective efficacy of a new fusion anti-caries dna vaccine encoding antigens of both streptococcus mutans and streptococcus sobrinus]. | to construct a new fusion anti-caries dna vaccine pgjgac/vax encoding antigens of both s. mutans and s. sobrinus so as to enhance the protective effect of dna vaccine against s. sobrinus infection. | 2009 | 20095345 |
| phylogenetic analyses and detection of viridans streptococci based on sequences and denaturing gradient gel electrophoresis of the rod shape-determining protein gene. | population analysis of viridans streptococci is important because these species are associated with dental caries, bacteremia, and subacute endocarditis, in addition to being important members of the human oral commensal microbiota. | 2009 | 21523207 |
| anticariogenic activity of the active fraction from isertia laevis against s. mutans and s. sobrinus: comparison of two extraction methods. | dental caries is considered a multi-factorial, infectious, chronic, localized, post-eruptive, transmissible disease that leads to the destruction of dental hard tissue. the recognition of streptococcus mutans as the major bacterial species involved in dental caries has led to the implementation of prevention and control measures for eliminating or reducing it in oral cavity. the main goal of research on medicinal plants is the search for substances or compounds with antimicrobial activity. the a ... | 2010 | 21638958 |
| microbial risk markers for childhood caries in pediatricians' offices. | dental caries in pre-school children has significant public health and health disparity implications. to determine microbial risk markers for this infection, this study aimed to compare the microbiota of children with early childhood caries with that of caries-free children. plaque samples from incisors, molars, and the tongue from 195 children attending pediatricians' offices were assayed by 74 dna probes and by pcr to streptococcus mutans. caries-associated factors included visible plaque, chi ... | 2010 | 20164496 |
| antibacterial activity of dental composites containing zinc oxide nanoparticles. | the resin-based dental composites commonly used in restorations result in more plaque accumulation than other materials. bacterial biofilm growth contributes to secondary caries and failure of resin-based dental composites. methods to inhibit biofilm growth on dental composites have been sought for several decades. it is demonstrated here that zinc oxide nanoparticles (zno-nps) blended at 10% (w/w) fraction into dental composites display antimicrobial activity and reduce growth of bacterial biof ... | 2010 | 20225252 |
| surface characteristics of orthodontic adhesives and effects on streptococcal adhesion. | in this study, we analyzed the surface roughness (sr) and surface free energy (sfe) characteristics of various orthodontic adhesives and their effects on the adhesion of mutans streptococci (ms). | 2010 | 20362908 |
| antimicrobial activity of super-oxidised water against oral microorganisms. | the radical anion of oxygen (o(-)) is extremely oxidative and shows high reactivity. in this study, the antibacterial activity of water super-oxidised water containing high concentration of o(-) (o(-)-water) was tested against cultured planktonic cells of cariogenic bacteria, periodontopathic bacteria and candida albicans. | 2010 | 20381790 |
| effects of a composition containing lactoferrin and lactoperoxidase on oral malodor and salivary bacteria: a randomized, double-blind, crossover, placebo-controlled clinical trial. | we report a clinical trial of the effects of test tablets containing bovine lactoferrin and lactoperoxidase on oral malodor and salivary bacteria. fifteen subjects with volatile sulfur compounds (vscs) in mouth air above the olfactory threshold (h(2)s >1.5 or ch(3)sh >0.5 ng/10 ml) as detected by gas chromatography were enrolled in the trial. either a test or a placebo tablet was ingested twice at 1-h intervals in two crossover phases. mouth air was monitored for vsc levels at the baseline befor ... | 2010 | 20512389 |
| effects of probiotic lactobacillus salivarius wb21 on halitosis and oral health: an open-label pilot trial. | the objective of this study was to evaluate whether oral administration of lactobacilli alters the degree of halitosis and clinical conditions associated with halitosis. | 2010 | 20659698 |
| antibacterial activity of various self-etching adhesive systems against oral streptococci. | the antibacterial properties of self-etching adhesive systems constitute an important issue in operative dentistry, since viable bacteria can still be present after cavity preparation. the current study evaluated the antibacterial activity of five one-step self-etching adhesives (seas) and four self-etching primers (seps) against oral streptococci. clearfil s3 (s3), one-up bond f plus (ou), futurabond nr (fb), gbond (gb), xeno iv (x4), clearfil se bond (se), clearfil protect bond (pb), adper se ... | 2010 | 20672730 |
| hydrophobicity test in mutans streptococci. | kinetic hydrophobic measurements were performed by confronting 40 mutans streptococci from thirty 10- to 20-year-old patients with 200 ml hexadecane (sigma). fourteen patients had high dental caries risk (group a), dmft + dmft > 5 with 3 or more active caries, and 16 had low dental caries risk (group b), dmft + dmft < 3 without active caries. twenty bacteria from group a and 20 bacteria from group b were typed using de la higuera's procedure and confirmed by api strip (bio-merieux). from the 14 ... | 2010 | 21638961 |
| antibacterial effects of 4-meta/mma-tbb resin containing chlorhexidine. | this study evaluated the antibacterial effects of 4-acryloyloxyethyl trimellitate anhydride/methyl methacrylate-tri-n-butylborane (4-meta/mma-tbb) resin containing chlorhexidine (chx) digluconate. the chx was incorporated into the resins at varying concentrations from 0.0 (control) to 3.0%. the antibacterial effect of each resin against seven microorganisms was examined using agar diffusion tests. growth inhibition of two streptococci was also tested in brain heart infusion (bhi) liquid broth co ... | 2010 | 20024968 |
| the inhibitory effects of mushroom extracts on sucrose-dependent oral biofilm formation. | mushrooms contain large quantities of alpha-glucans. shiitake (lentinula edodes), japan's most popular edible mushroom, has been reported to contain about 6% (weight/dried weight) of alpha-(1,3)-glucan. this glucan is one of the major components of oral biofilm formed by the cariogenic bacteria streptococcus mutans and streptococcus sobrinus. we found that extracts from shiitake and other edible mushrooms could reduce preformed biofilms of s. mutans and s. sobrinus in the presence of dextranase. ... | 2010 | 19902205 |
| caries experience and quantification of streptococcus mutans and streptococcus sobrinus in saliva of sudanese schoolchildren. | streptococcus mutans and streptococcus sobrinus are among the most commonly isolated bacterial species implicated as etiological agents of dental caries. details of the composition of the oral microflora related to dental caries should aid in assessing the prevalence and risk of disease at an individual level. the aim of the present study was to determine the presence and relative amounts of s. mutans and s. sobrinus in the saliva samples obtained from schoolchildren in khartoum state, the sudan ... | 2010 | 20714152 |
| mutans streptococci and caries prevalence in children after early maternal caries prevention: a follow-up at eleven and fifteen years of age. | the efficacy of early maternal caries prevention in children was evaluated. | 2010 | 20838044 |
| diet and caries-associated bacteria in severe early childhood caries. | frequent consumption of cariogenic foods and bacterial infection are risk factors for early childhood caries (ecc). this study hypothesized that a short diet survey focused on frequency of foods, categorized by putative cariogenicity, would differentiate severe ecc (s-ecc) from caries-free children. children's diets were obtained by survey and plaque bacteria detected by pcr from 72 s-ecc and 38 caries-free children. s-ecc children had higher scores for between-meal juice (p < 0.01), solid-reten ... | 2010 | 20858780 |
| characterization of the streptococcus sobrinus acid-stress response by interspecies microarrays and proteomics. | streptococcus mutans and streptococcus sobrinus are considered the primary organisms responsible for human dental caries. the ability to generate acids and to adapt to low ph conditions is directly associated with the cariogenic potential of these bacteria. to survive acidic conditions, both species have been shown to mount an acid-tolerance response (atr). however, previous characterization of the s. sobrinus atr identified critical differences in the mechanisms of acid adaptation between s. mu ... | 2010 | 20883222 |
| investigation of supragingival plaque microbiota in different caries status of chinese preschool children by denaturing gradient gel electrophoresis. | this study aimed to detect differences in the richness of total supragingival plaque microbiota as well as the species composition of oral streptococci involved in the different stages of dental caries. forty-five plaque samples were collected from caries-moderate (cm, 4 ≤ dmfs ≤ 6), caries-susceptible (cs, dmfs ≥ 10), and age-matched caries-free children separately. total dna was isolated directly from each sample, and polymerase chain reaction-denaturing gradient gel electrophoresis (pcr-dgge) ... | 2010 | 20927511 |
| effect of biofilm on the repair bond strengths of composites. | composite restorations degrade during wear, but it is unknown how wear affects the composite surface and influences composite-to-composite bonding in minimally invasive repair. here, it is hypothesized that in vitro exposure of composites to oral biofilm yields clinically relevant degradation of composite surfaces, and its influence on composite-to-composite bonding is determined. biofilms on composite surfaces in vitro increased their roughness and decreased filler particle exposure, except for ... | 2010 | 20940354 |
| antibacterial activity of the essential oil from rosmarinus officinalis and its major components against oral pathogens. | the essential oil of rosmarinus officinalis l. (rosemary) was obtained by hydro-distillation and analysed by gas chromatography-mass spectrometry. sixty-two constituents were identified, representing 98.06% of the total oil content. oxygenated monoterpenes were the predominant components. the rosemary oil was characterized as having prominent (> 5%) contents of camphor (18.9%), verbenone (11.3%), a-pinene (9.6%), beta-myrcene (8.6%), 1,8-cineole (8.0%), and beta-caryophyllene (5.1%). the antimic ... | 2010 | 21138060 |
| microbiological profiles in saliva and supragingival plaque from caries-active adolescents before and after a short-term daily intake of milk supplemented with probiotic bacteria - a pilot study. | the aim of the present pilot study was to investigate the microbial profile in saliva and supragingival plaque samples collected from caries-active adolescents before and after a daily short-term intake of milk supplemented with the probiotic bacteria. | 2010 | 21180676 |
| kinetics of dextran-independent α-(1→3)-glucan synthesis by streptococcus sobrinus glucosyltransferase i. | glucosyltransferase (gtf)-i from cariogenic streptococcus sobrinus elongates the α-(1→3)-linked glucose polymer branches on the primer dextran bound to the c-terminal glucan-binding domain. we investigated the gtf-i-catalyzed glucan synthesis reaction in the absence of the primer dextran. the time course of saccharide production during dextran-independent glucan synthesis from sucrose was analyzed. fructose and glucose were first produced by the sucrose hydrolysis. leucrose was subsequently prod ... | 2010 | 21182591 |
| inhibitory properties of coffea canephora extract against oral bacteria and its effect on demineralisation of deciduous teeth. | the antibacterial activity of coffea canephora extract was evaluated in vitro against streptococcus mutans and streptococcus sobrinus. the viability of planktonic cells was analysed by susceptibility tests (mic and mbc) and time-kill assays. the effect of the extract on dental demineralisation was also investigated. | 2010 | 21185010 |
| effects of xylitol on survival of mutans streptococci in mixed-six-species in vitro biofilms modelling supragingival plaque. | xylitol has been claimed to reduce mutans streptococci (ms) in dental plaque by energy-consuming futile metabolic cycles. this study aimed to investigate the effects of xylitol on ms in an in vitro 6-species oral biofilm model. each multispecies biofilm contained either a laboratory reference strain, a fresh isolate, a xylitol-sensitive or a xylitol-resistant strain of streptococcus mutans or streptococcus sobrinus. biofilms, grown on pellicle-coated hydroxyapatite discs, were fed with a glucose ... | 2010 | 21196732 |
| streptococcus mutans and streptococcus sobrinus are able to adhere and invade human gingival fibroblast cell line. | streptococcus mutans and streptococcus sobrinus, the principal etiologic agents of caries decay of teeth, are generally acquired in oral cavity at the moment of tooth eruption. however, as s. mutans has been detected in oral cavity of predentate children, the eruption of teeth seems not to be a necessary prerequisite, suggesting that this species may be not confined to dental plaque. here, we evaluate the ability of s. mutans and s. sobrinus in planktonic and biofilm lifestyle to adhere, invade ... | 2010 | 21244775 |
| effects of a bio-assay guided fraction from polygonum cuspidatum root on the viability, acid production and glucosyltranferase of mutans streptococci. | polygonum cuspidatum root has been traditionally used for the treatment of dental diseases in korea. the purpose of this study was to evaluate effects of p. cuspidatum root on the development of dental caries, especially its effects against bacterial viability and caries-inducing factors of streptococcus mutans and streptococcus sobrinus. among methanol extract of p. cuspidatum root and its fraction tested, ethyl acetate fraction, composed of polydatin, resveratrol, anthraglycoside b, and emodin ... | 2010 | 19616082 |
| renolase maternal immunization confers caries protection on offspring. | therapeutic vaccination with streptococcus sobrinus recombinant enolase (renolase) protects rats from dental caries. here, we investigated the effect that maternal renolase vaccination before pregnancy had on the offspring's immune response to s. sobrinus oral infection and dental caries progression. female wistar rats were immunized by intranasal and subcutaneous routes with renolase adsorbed onto aluminum hydroxide as adjuvant or similarly treated with the adjuvant alone (sham-immunized). ten ... | 2011 | 21297015 |
| antibacterial activity of 15-deoxygoyazensolide isolated from the stems of minasia alpestris (asteraceae) against oral pathogens. | this work reports the isolation of the sesquiterpene lactone 15-deoxygoyazensolide from the stems of minasia alpestris and the evaluation of its antimicrobial activity against the following oral pathogens: enterococcus faecalis, streptococcus salivarius, streptococcus sobrinus, streptococcus mutans, streptococcus mitis, streptococcus sanguinis, and lactobacillus casei. despite the cytotoxicity and genotoxicity of other sesquiterpene lactones of the furanoheliangolide-type, our results revealed t ... | 2011 | 21328129 |
| an artificial biofilm induced secondary caries model for in vitro studies. | the aim of this study was to establish a new in vitro model for biofilm induced secondary caries studies using an oral biofilm reactor. | 2011 | 21332739 |
| antimicrobial effect of korean propolis against the mutans streptococci isolated from korean. | the aim of this study was to determine the optimal concentration of korean propolis against clinical isolates of mutans streptococci (ms) from koreans. the antimicrobial activity was evaluated using the minimum inhibitory concentration (mic) and time-kill curves against mutans streptococci. the mic(90) values of propolis for ms were 35 µg/ml. propolis had a bacteriostatic effect on streptococcus mutans atcc 25175(t) and bactericidal effects on streptococcus sobrinus atcc 33478(t) at > 2 × mic (7 ... | 2011 | 21369995 |
| prunus mume extract exhibits antimicrobial activity against pathogenic oral bacteria. | prunus mume is a common fruit in asia, which has been used in traditional chinese medicine. in this study, we focused on the antimicrobial properties of prunus mume extract against oral pathogens related to dental caries and periodontal diseases. | 2011 | 21401748 |
| antimicrobial activity of bifidobacterium spp. isolated from healthy adult koreans against cariogenic microflora. | objective: dental caries is the main common infectious disease in the human oral cavity. streptococcus mutans and streptococcus sobrinus were reported to be the most important etiological factors in human dental caries. thus, we examined the inhibitory effects of bifidobacterium spp. cells and culture supernatants against s. mutans and s. sobrinus, including streptococcus gordonii, and aggregatibacter actinomycetemcomitans, which is associated with periodontal disease. methods: mutans streptococ ... | 2011 | 21439550 |
| development and evaluation of a safe and effective sugar-free herbal lollipop that kills cavity-causing bacteria. | dental caries (tooth decay) is caused by a specific group of cariogenic bacteria, like streptococcus mutans, which convert dietary sugars into acids that dissolve the mineral in tooth structure. killing cariogenic bacteria is an effective way to control or prevent tooth decay. in a previous study, we discovered a novel compound (glycyrrhizol a), from the extraction of licorice roots, with strong antimicrobial activity against cariogenic bacteria. in the current study, we developed a method to pr ... | 2011 | 21449211 |
| effects of compounds found in nidus vespae on the growth and cariogenic virulence factors of streptococcus mutans. | nidus vespae (honeycomb) is a kind of traditional chinese medicine that has been demonstrated to inhibit the growth and acid-production of oral cariogenic bacteria. subsequent studies showed that the chloroform/methanol (chl/meoh) chemical extraction of nidus vespae was the most effective inhibitor of growth and acidogenicity of streptococcus mutans. in this study, we isolated the chemical compounds of the nidus vespae chl/meoh extraction, tested their antimicrobial activity against six cariogen ... | 2011 | 21498060 |
| morphological differentiation between s. mutans and s. sobrinus on modified sb-20 culture medium. | due to the major role of streptococcus mutans and streptococcus sobrinus in the etiology of dental caries, it is important to use culture media that allow for differentiating these bacterial species. the aim of this study was to evaluate the suitability of a modified sb-20 culture medium (sb-20m) for the isolation and morphological differentiation of s. mutans and s. sobrinus, compared to biochemical identification (biotyping). saliva samples were collected using the spatula method from 145 chil ... | 2011 | 20092983 |
| Isoflavonoids and Coumarins from Glycyrrhiza uralensis: Antibacterial Activity against Oral Pathogens and Conversion of Isoflavans into Isoflavan-Quinones during Purification. | Phytochemical investigation of a supercritical fluid extract of Glycyrrhiza uralensis has led to the isolation of 20 known isoflavonoids and coumarins, and glycycarpan (7), a new pterocarpan. The presence of two isoflavan-quinones, licoriquinone A (8) and licoriquinone B (9), in a fraction subjected to gel filtration on Sephadex LH-20 is due to suspected metal-catalyzed oxidative degradation of licoricidin (1) and licorisoflavan A (2). The major compounds in the extract, as well as 8, were evalu ... | 2011 | 22074222 |
| Clinically acceptable restorations may be a hotbed for cariogenic microbes. | Gerodontology 2011; doi: 10.1111/j.1741-2358.2011.00571.x Clinically acceptable restorations may be a hotbed for cariogenic microbes Objective: The aim of this study was to investigate the cross-sectional association of dental restorations with salivary cariogenic pathogens among the elderly to establish effective parameters of caries risk for this population. Materials and methods: Stimulated whole saliva was collected from 289 community-dwelling older adults (66.2 ± 3.9 years old) who had 20 ... | 2011 | 22004112 |
| The inhibition of eugenol on glucan is essential for the biofilm eradication effect on caries-related biofilm in an artificial mouth model. | This study aimed to evaluate the inhibitory effects of herbal extracts on caries-related bacteria, glucan and biofilm in vitro. Sensitive tests of bacteria were carried out by broth dilution method on a 96-microwell plate. Glucan inhibition tests were carried out using the phenol sulphate method. A minimum biofilm inhibitory concentration (MBIC) test was performed in an artificial mouth model. The results of the MBIC of agents were 8, 16 and 32?mg?mL(-1) for eugenol, tannic acid and magnolol, re ... | 2011 | 21950685 |
| The in vitro antimicrobial activity of natural infant fluoride-free toothpastes on oral micro-organisms. | The objective of this study was to evaluate the antimicrobial activity of six toothpastes for infants: 3 fluoride-free experimental toothpastes--cashew-based, mango-based and without plant extract and fluoride compared with 2 commercially fluoride-free toothpastes and 1 fluoridated toothpastes. | 2011 | 22041001 |
| Body weight maintenance and levels of mutans streptococci and lactobacilli in a group of Swedish women seven years after completion of a Weight Watchers' diet. | The long-term effect of the WW programme on weight and oral cariogenic bacteria was evaluated after 7 yr. All WW who completed the 8-wk dietary regimen in an earlier study (n=33) and the persons in the reference group (REF) (n=27) were invited to participate. The salivary secretion rate, numbers of mutans streptococci (MS) and lactobacilli (lbc) were determined. The WW were weighed. Sustaining a 5% weight loss from the initial weight was regarded as successful weight maintenance. An interview ac ... | 2011 | 22135941 |