Publications

immune response to haemophilus parainfluenzae in patients with chronic obstructive lung disease.	haemophilus parainfluenzae is often isolated from the sputa of patients with chronic obstructive lung disease. we have investigated the immune response to this organism in patients with chronic bronchitis (n = 3) and bronchiectasis (n = 10) and in healthy controls (n = 9). outer membrane proteins (omps) of h. parainfluenzae were purified for use in enzyme-linked immunosorbent and immunoblot assays. whole-cell h. parainfluenzae preparations were used to adsorb antibodies from serum samples, which ...	2000	10618272
immune response of tonsillar lymphocytes to haemophilus parainfluenzae in patients with iga nephropathy.	the pathogenesis of iga nephropathy (igan) is unclear. we have previously shown glomerular deposition of haemophilus parainfluenzae (hpi) antigens and the presence of iga antibody against hpi antigens in patients with igan. we examined the immune response to hpi antigens in tonsillar lymphocytes from patients with igan. lymphocytes isolated from the palatine tonsils of 13 igan patients and 16 patients with chronic tonsillitis but without renal disease were used as controls. we examined lymphocyt ...	2000	10632671
[the role of international parasitology congresses in the development of the parasitological sciences].		2000	95817
symbols and selectivity: a statistical analysis of native american medical ethnobotany.	native americans use a wide range of plants medicinally. many of these plants have profound meaning to their users. does this mean, as some assert, that tribal medicine is "all placebo"? since the essential character of meaning is the arbitrariness of the sign, then insofar as this medicine is symbolic, the plants used medicinally will be a random representation of plants available in nature. several regression analyses of plants used by native americans on plants available to them indicate subs ...	2000	94415
use of a monoclonal antibody (w6/32) in structural studies of hla-a,b,c, antigens.		2000	87477
[isolation of mutant cells for the studies of cell architecture, biological transport, and cellular responses].		2000	1745790
the effect of rectal examination on serum acid phosphatase.		2000	90146
the behavioral effects of phencyclidine in animals.		2000	101876
progress with several models for the study of the sar of hallucinogenic agents.		2000	101879
the problems of massive small bowel resection and difficulties encountered in management.	massive small bowel resection is imperative in the management of several pathological conditions and is accompanied by high operative mortality. in those that survive, serious nutritional disturbances are inevitable. intestinal adaptation is said to occur but cannot be relied upon. long-term parenteral nutrition is problematical and often unsuccessful. many surgical procedures have been adopted in an effort to improve prognosis and have been found wanting. controlled experimental studies in the ...	2000	97646
ocular manifestations of phycomycosis in a diabetic.		2000	97389
a new hla--c specificity (t9) in linkage disequilibrium with hla--b14.		2000	87025
cure of aplastic anaemia in paroxysmal nocturnal haemoglobinuria by marrow transfusion from identical twin: failure of peripheral-leucocyte transfusion to correct marrow aplasia.	the ability of syngeneic peripheral leucocytes to cure marrow aplasia was tested in a patient with paroxysmal nocturnal haemoglobinuria (p.n.h.). transfusion of 7.1x10(10) white cells obtained by leucopheresis from an identical-twin donor, providing 3.4x10(4) myeloid progenitors (c.f.u.-c)/kg, failed to improve marrow function within two months. in contrast, transfusion of 1.3x10(10) nucleated bone-marrow cells, representing 6.4x10(4) c.f.u.-c/kg, from the same donor resulted in prompt bone-marr ...	2000	87615
the can serum: demonstrating further polymorphism of m and n blood group antigens.	an antibody defining an antigen that is very similar in structure to m is described. the reactions of this antibody are considered in the light of what is now known of the biochemical structure of the m and n blood group antigens.	2000	86213
the effect of combination chemotherapy on neutrophil function in cancer patients.	the effect of adjuvant and palliative combination chemotherapy (vincristine, meccnu, 5-fluorouracil) on neutrophil function was studied in 18 patients prior to and during the anticancer treatment. neutrophil responsiveness was assessed by leukocyte chemotaxis and chemiluminescence. no impairment could be observed in the circulating phagocyte function in either of the 2 groups before or in connection with short or long-term treatment.	2001	88258
research needs in low vision.	research needs are presented for several areas of low vision: (1) reading and learning, (2) new low-vision aids, (3) modifying the environment, (4) utilization of disciplines, (5) new technologies, and (6) integrating low-vision services.	2001	88182
posttraumatic epilepsy and acute intermittent porphyria: effects of phenytoin, carbamazepine, and clonazepam.	a patient with uncontrolled posttraumatic epilepsy and acute intermittent prophyria was subjected to successive therapeutic trials with phenytoin, carbamazepine, and clonazepam, while eating an adequate diet. both phenytoin and carbamazepine treatments caused significant increases in porphobilinogen excretion and appeared to induce acute porphyric attacks. in contrast, treatment with clonazepam under rigid dietary control for 10 days caused no increase in porphilbinogen excretion. during the sub ...	2001	98734
use of thermal image film for demonstrations of computer-assisted searching.		2001	88978
variation in amount of enzyme protein in natural populations.	among strains of drosophila melanogaster each derived from a single fertilized female taken from natural populations, there is variation in both alcohol dehydrogenase (adh) activity and the amount of adh protein. the correlation between adh activity and number of molecules over all strains examined is 0.87 or 0.96 in late third instar larvae depending on whether the substrate is 2-propanol or ethanol. with respect to the two common electrophoretic allozymic forms, f and s, segregating in these p ...	2001	98165
[immunohistochemical study of the differentiation of the cephalic lobe of the adenohypophysis in chick embryos].	it was shown by means of indirect immunofluorescence that acth appeared in the cephalic lobe of the chick embryo pituitary beginning from the 8th day of the development. a new tissue-specific antigen (a3) is revealed, which is localized in the cephalic lobe of adenohypophysis and becomes manifest at the 7th day of embryogenesis. quantitative analysis of acth and a3 localization in the cells of 11-day chick embryo adenohypophyses allows a conclusion that a3 is localized in corticotropic cells.	2001	88969
[colecystitis caused by haemophilus parainfluenzae. description of a case].		2001	12876595
preservation of haemophilus influenzae and haemophilus parainfluenzae at -70 degrees c.	we have studied the viability of haemophilus spp. preserved for 5 to 12 months at -70 degrees c. the following media were used: laboratoire de santé publique du québec (lspq) preservation medium, trypticase soy broth with 10 degrees c (vol/vol) glycerol and 40 degrees c (vol/vol) horse serum (tsbg), and levinthal's broth (lb) medium. three clinical isolates of both h. influenzae and h. parainfluenzae were used. after 5 months no differences in viability were observed between strains preserved in ...	2001	11812055
suppression of an external demand pacemaker by diaphragmatic myopotentials: a sign of electrode perforation?	transient pacemaker inhibition was observed in a patient with an external bipolar demand pulse generator. recordings of the proximal, distal and bipolar electrograms showed extracardiac myopotentials only in the unipolar distal and bipolar configuration. these myopotentials which caused inhibition of the pulse generator were related to respiration and other maneuvers that resulted in active contraction of the diaphragm, thus proving their diaphragmatic origin.	2001	95280
bacterial infection in chronic obstructive pulmonary disease in 2000: a state-of-the-art review.	chronic obstructive pulmonary disease (copd) is the fourth leading cause of death in the united states. the precise role of bacterial infection in the course and pathogenesis of copd has been a source of controversy for decades. chronic bacterial colonization of the lower airways contributes to airway inflammation; more research is needed to test the hypothesis that this bacterial colonization accelerates the progressive decline in lung function seen in copd (the vicious circle hypothesis). the ...	2001	11292642
a novel heme protein, the cu,zn-superoxide dismutase from haemophilus ducreyi.	haemophilus ducreyi, the causative agent of the genital ulcerative disease known as chancroid, is unable to synthesize heme, which it acquires from humans, its only known host. here we provide evidence that the periplasmic cu,zn-superoxide dismutase from this organism is a heme-binding protein, unlike all the other known cu,zn-superoxide dismutases from bacterial and eukaryotic species. when the h. ducreyi enzyme was expressed in escherichia coli cells grown in standard lb medium, it contained o ...	2001	11369755
a histidine-rich metal binding domain at the n terminus of cu,zn-superoxide dismutases from pathogenic bacteria: a novel strategy for metal chaperoning.	a group of cu,zn-superoxide dismutases from pathogenic bacteria is characterized by histidine-rich n-terminal extensions that are in a highly exposed and mobile conformation. this feature allows these proteins to be readily purified in a single step by immobilized metal affinity chromatography. the cu,zn-superoxide dismutases from both haemophilus ducreyi and haemophilus parainfluenzae display anomalous absorption spectra in the visible region due to copper binding at the n-terminal region. reco ...	2001	11369756
optimisation of the prevention and treatment of bacterial endocarditis.	this paper reviews currently established guidelines for the prevention and treatment of bacterial endocarditis. endocarditis remains a life-threatening disease with substantial morbidity and mortality. primary prevention of endocarditis, whenever possible, is therefore very important. in an individual with endocarditis, rapid diagnosis and effective treatment are essential to good patient outcome. the guidelines discussed here are largely based on those issued by the american heart association. ...	2001	11419916
rrn operons in haemophilus parainfluenzae and mosaicism of conserved and species-specific sequences in the 16s-23s rdna long spacer.	the mosaic organisation of short-sequence boxes was analysed in the cloned and sequenced long ribosomal spacer (547 bp) of haemophilus parainfluenzae gr. comparison and alignment of both the long and the short spacer were performed in h. parainfluenzae and h. influenzae rd. the long spacer contained two trna genes (trna(ala) and trna(ile)) which are highly homologous to the corresponding genes found in the spacers of other species, such as haemophilus spp., actinobacillus spp., and plesiomonas s ...	2001	11446514
the efficacy and safety of two oral moxifloxacin regimens compared to oral clarithromycin in the treatment of community-acquired pneumonia.	an international multi-centre, randomized, prospective, double-blind study compared oral moxifloxacin (200 mg or 400 mg once daily for 10 days) with oral clarithromycin (500 mg, twice daily for 10 days) in the treatment of community-acquired pneumonia (cap). the clinical success rate in the evaluable population at the primary efficacy assessment, 3-5 days after the end of study treatment, was 93.9% in patients treated with 200 mg moxifloxacin; 94.4%, with 400 mg moxifloxacin; and 94.3%, with cla ...	2001	11453311
remarkable conservation of translation initiation factors: if1/eif1a and if2/eif5b are universally distributed phylogenetic markers.	initiation of protein biosynthesis is an essential process occurring in cells throughout the three phylogenetic domains, bacteria, archaea, and eucarya. if1/eif1a and if2/eif5b, two conserved translation initiation factors are involved in this important step of protein biosynthesis. the essentiality, universal distribution, conservation, and interspecies functional homology of both factors are a unique combination of properties ideal for molecular phylogenetic studies as demonstrated by the exte ...	2001	11699879
pcr-based detection, restriction endonuclease analysis, and transcription of tonb in haemophilus influenzae and haemophilus parainfluenzae isolates obtained from children undergoing tonsillectomy and adenoidectomy.	we developed and evaluated a pcr-based-restriction endonuclease analysis method to detect and analyze the tonb gene of haemophilus influenzae and haemophilus parainfluenzae from pediatric patients undergoing tonsillectomy and adenoidectomy. multiple sites from the same patient, including the surface of adenoids and tonsils, as well as the core of tonsils, were cultured on chocolate agar and identified using standard procedures and the api nh kit. a total of 55 h. influenzae isolates were recover ...	2001	11238199
haemophilus parainfluenzae complicating total hip arthroplasty: a rapid failure.	we present a case of rapid failure of a total hip arthroplasty caused by infection with haemophilus parainfluenzae. the septic loosening occurred over a period of 3 months and followed a dental extraction that had not been covered by prophylactic antibiotics. this failure occurred in a previously well-functioning and asymptomatic prosthetic joint.	2002	11805937
[37 tumors of the jejuno-ileum].	the present paper reports on 37 primary tumours of the jejunoileum, of which 19 malignant and 18 benign. the authors emphasize the difficulty of establishing a diagnosis before the onset of one of the dramatic complications in the evolution of tumours of the small intestine. the patients were admitted for the following complications: occlusive syndrome -- 28 cases (72.9%), peritoneal syndrome -- 6 cases (16.2%) and hemorrhagic syndrome -- 3 cases (8.1%). all the patients with a peritoneal and he ...	2002	127194
experimental nephropathy induced by haemophilus parainfluenzae antigens.	we have demonstrated that outer membrane antigens of haemophilus parainfluenzae (omhp) are potentially involved in iga nephropathy (igan). in this study, we established an experimental model of igan using omhp antigens and investigated the nephritogenicity of omhp antigens.	2002	11867953
haemophilus parainfluenzae and fusobacterium necrophorum liver abscess: a case report.	liver abscess is a potentially life-threatening disease. the clinical features of pyogenic liver abscess are variable and probably correlate with a variety of pathogenic microorganisms and underlying diseases that may be involved. the most common pathogen of liver abscess in taiwan is klebsiella pneumoniae. diabetes mellitus and hepatobiliary calculus are major diseases associated with liver abscess. haemophilus parainfluenzae is a commensal of the upper respiratory tract, but is an uncommon iso ...	2002	11950124
oral bacteria influenced by the functional status of the elderly people and the type and quality of facilities for the bedridden.	to analyse the relationship between oral bacteria and the health and functional status of the elderly.	2002	12174048
relationship between bacterial colonisation and the frequency, character, and severity of copd exacerbations.	patients with chronic obstructive pulmonary disease (copd) are prone to frequent exacerbations which are a significant cause of morbidity and mortality. stable copd patients often have lower airway bacterial colonisation which may be an important stimulus to airway inflammation and thereby modulate exacerbation frequency.	2002	12200518
the italian epidemiological survey 1997-1999. antimicrobial susceptibility data of haemophilus influenzae, haemophilus parainfluenzae and moraxella catarrhalis in italy.	the italian epidemiological survey began a surveillance study with the aim of monitoring the antimicrobial resistance of respiratory pathogens. from 1997 to 1999, 2028 strains of haemophilus influenzae and 523 strains of haemophilus parainfluenzae were collected from 59 clinical microbiology laboratories distributed throughout italy. in 1998, the study was extended to include moraxella catarrhalis and a total of 360 isolates were collected. there was a significant increase in the beta-lactamase ...	2002	12385682
primary peritonitis in a child caused by haemophilus parainfluenzae.	a case of primary peritonitis caused by haemophilus parainfluenzae in a previously healthy child is presented. to our knowledge, this is the first such documented case.	2002	12598974
dna-based subtypes and antimicrobial susceptibility profiles of haemophilus influenzae and haemophilus parainfluenzae isolated from different tonsillar sites of children undergoing tonsillectomy and/or adenoidectomy.	we did a comparative analysis between dna-based subtypes and antimicrobial susceptibility profiles on haemophilus influenzae and haemophilus parainfluenzae, isolated from multiple tonsillar sites per individual from patients with chronic recurrent tonsillitis and/or tonsillar idiopathic hypertrophy and undergoing tonsillectomy and/or adenoidectomy. a total of eighty-eight haemophilus isolates were obtained aseptically from the surface and core of tonsils and/or adenoids of 32 out of 60 patients ...	2002	15298475
[clinical observations with a preparation with a base of 4-isobutylphenyl-2-propionate of lysine in degenerative rheumatic diseases].		2002	120797
[lamellar coxitis. apropos of 30 cases].	the authors have studied 30 cases of acute necrosis of articular cartilage complicating slipped capital femoral epiphysis. they recall the main features of this condition: stiffness and narrowing of the joint space. they analyse the importance of the degree of slipping and of the type of treatment in the aetiology of this complication. weight bearing should be suppressed as early as possible, for a long period of time. however early signs of degenerative arthrosis were found in most of the hips.	2002	139662
evaluation of carotid stenosis by phonoangiography.	quantitative spectral (frequency) analyses were performed on 60 carotid bruits in 48 patients with suspected carotid stenosis. the technic was totally noninvasive. bruits were recorded at the skin surface, analyzed by a minicomputer, and the degree of arterial stenosis estimated using a recently derived theory of sound production by turbulent blood flow. this method has been named phonoangiography. fifty of the 60 bruits (83 per cent) had spectrums characteristic of turbulent blood flow, and a r ...	2002	127121
a community-based hospice program.		2002	1771046
value of transesophageal echocardiography during complex or high-risk coronary interventions in the cardiac catheterization laboratory.	the increasing complexity of coronary intervention and the limitations of hemodynamic and electrocardiographic monitoring have facilitated the introduction of new imaging techniques in the cardiac catheterization laboratory. transesophageal echocardiography (tee) has proved valuable for left ventricular (lv) monitoring during high-risk surgery, but its reported use in the cardiac catheterization laboratory has been limited. accordingly, we assessed the feasibility and value of tee during complex ...	2002	1746426
[the surgical treatment of superficial thrombophlebitis].		2002	1767155
[education of the diabetic patient].		2003	254366
barbara's resuscitation dilemma.		2003	254301
widening their horizons: a model career development program for severely physically disabled youth.		2003	155866
[hygienic characteristics of the regimen in leningrad schools and extended-day groups].		2003	149702
[on the 70th birthday of prof g. z. pitskhelauri].		2003	149699
the plasma lipoproteins.		2003	201162
the invariance of unique white; a possible implication for normalizing cone action spectra.	the locus of unique white was measured for two observers over a wide range of stimulus intensities, using both direct matching and absolute judgements. chromaticity coordinates of each observer's unique white were found to be invariant over a range of about 4 log units. this result is discussed in the context of the class of models that explain the intensity-evoked change in perceived color (bezold-brücke effect) on the basis of response compression in color channels. invariance of unique white ...	2003	1771798
dermatofibrosarcoma protuberans in northern nigeria: a clinico-pathological review of 17 cases.		2003	149627
[post-traumatic fat embolism (21 treated cases during 4 years)].		2003	154717
ectopic acth production in disseminated prostatic adenocarcinoma.	the second fully documented case of acth-producing prostatic adenocarcinoma with elevated plasma and tissue levels of acth is presented. the distinguishing characteristics of acth-producing extrapituitary neoplasms and the various modes of therapy are discussed.	2003	166477
infective endocarditis after oral body piercing.	body piercing has become an increasingly common practice in the united states and elsewhere. although perceived as a relatively safe practice, it poses the risk of numerous infectious complications. oral body piercing in particular has significant potential risk given the known relationship of oral flora to bacteremia. we describe a patient who developed infective endocarditis shortly after undergoing oral piercing.	2003	12943601
microbial etiologies in community acquired pneumonia (cap).	the objective of the study was determination of bacterial etiologic factors, including antibiotic atypical pathogens, of community acquired pneumonia (cap) in adults and of sensitivity of isolated strains. the examined group comprised 50 patients with clinical and x-ray image of pneumonia. patients' expectoration sputum was analyzed. amongst all isolated bacteria, the most frequent were staphylococcus aureus - 17.9%, haemophilus parainfluenzae - 12.5% and h. influenzae - 8.9%. identification of ...	2003	15315033
bacterial exacerbations of chronic obstructive pulmonary disease. the role of lung function in aetiology of exacerbation.	the objective of the study was determination of the most frequent bacterial factors, including haemophilus parainfluenzae, suspected of causing copd exacerbation, of the relation between bacterial strains and respiratory system functional status as well as of antibiotic sensitivity of sputum isolated bacteria. the examined group comprised 28 patients treated in the pulmonary department of medical university of lublin. the subjects fulfilled the criteria of type i copd bacterial exacerbation. pat ...	2003	15315034
activities of a new oral streptogramin, xrp 2868, compared to those of other agents against streptococcus pneumoniae and haemophilus species.	mic methodology was used to test the antibacterial activity of xrp 2868, a new oral combination of two semisynthetic streptogramins, rpr 132552a and rpr 202868, compared to activities of other antibacterial agents against pneumococci, haemophilus influenzae, and haemophilus parainfluenzae. for 261 pneumococci, xrp 2868 and pristinamycin mics were similar, irrespective of penicillin g and erythromycin a susceptibilities (mic at which 50% of isolates were inhibited [mic(50)], 0.25 micro g/ml; mic( ...	2003	14506040
a 2-year-old girl with a several-day history of vomiting and lethargy.		2003	14508890
amoxicillin/clavulanate potassium extended release tablets: a new antimicrobial for the treatment of acute bacterial sinusitis and community-acquired pneumonia.	community-acquired bacterial respiratory tract infections are among the most common health disorders requiring medical care and are associated with substantial morbidity, mortality, and direct and indirect costs. recent increases in the prevalence of antimicrobial resistance have resulted in reduced susceptibility of the most common respiratory tract bacterial pathogens to a number of antimicrobials. amoxicillin/clavulanate potassium extended release (er) tablets (augmentin xr, glaxosmithkline) ...	2003	14521493
[monoarthritis with haemophilus parainfluenzae septicaemia during multiple myeloma of the bones].		2003	14534478
susceptibilities of fluoroquinolone-resistant haemophilus parainfluenzae isolates from japanese patients with respiratory infections to five fluoroquinolones and other antimicrobial agents.		2003	14638520
haemophilus parainfluenzae infection of respiratory mucosa.	the pathogenicity of haemophilus parainfluenzae (hpi) in the respiratory tract is unclear, in contrast to the accepted pathogenicity of its close relative non-typable h. influenzae. we have investigated the interaction of two hpi isolates with the mucosa of adenoid and bronchial tissue organ cultures. the adherence of bacteria to the mucosa of organ cultures, the effect of broth culture filtrates on human nasal epithelium, and interleukin (il)-8 production by a549 cell cultures was investigated. ...	2003	12693797
comparative in vitro potency of amoxycillin-clavulanic acid and four oral agents against recent north american clinical isolates from a global surveillance study.	the in vitro activity of amoxycillin-clavulanic acid was compared with four comparator oral antimicrobial agents; ampicillin, azithromycin, cefuroxime and trimethoprim-sulphamethoxazole against 4536 recent clinical isolates covering 29 species isolated in the us and canada between 1997 and 1999. based upon minimum inhibitory concentrations (mics), amoxycillin-clavulanic acid was the most active agent against many gram-positive species and phenotypes including methicillin susceptible staphylococc ...	2003	12727075
microbial population diversity in the urethras of healthy males and males suffering from nonchlamydial, nongonococcal urethritis.	nonchlamydial, nongonococcal urethritis (ncngu) is suggested to be a sexually transmitted disease in men. ncngu patients were compared to control subjects with regard to the presence of potentially infectious bacteria in the first void urine. patients' pre- and post-antibiotic-treatment urine samples and two samples obtained 2 weeks apart from healthy volunteers, who did not receive antibiotic therapy, were analyzed with broad-spectrum pcr tests aiming at eubacterial small subunit rrna genes. re ...	2003	12734237
hacek endocarditis in infants and children: two cases and a literature review.	we report 2 cases of haemophilus parainfluenzae endocarditis and review 34 cases of hacek endocarditis from the literature. hacek organisms are the most common cause of gram-negative endocarditis in children. they have a propensity to form friable vegetations (especially h. parainfluenzae) that break off and cause symptomatic emboli. hacek endocarditis (from a review of the 36 published cases) may involve previously normal hearts (33%), may be complicated by embolization (31%) and may require ve ...	2003	12799515
activities of hmr 3787 and ru 64399 compared with those of four other agents against haemophilus influenzae and haemophilus parainfluenzae.	activities of hmr 3787, a new 2-fluoroketolide, and its (des)-fluor derivative, ru 64399, were tested against 111 haemophilus influenzae and 26 h. parainfluenzae strains and compared with those of telithromycin, erythromycin, azithromycin, and clarithromycin. hmr 3787 and ru 64399 mics were comparable with those of azithromycin but were less affected by incubation in co(2). time-kill studies of 12 strains showed that hmr 3787, ru 64399, and telithromycin were bactericidal against all strains aft ...	2003	12499225
nephrotic syndrome with crescent formation and massive iga deposition following allogeneic bone marrow transplantation for natural killer cell leukemia/lymphoma.	we describe herein a case of nephrotic syndrome (ns) following allogeneic bone marrow transplantation (allo-bmt) for natural killer cell leukemia/lymphoma. histologic studies defined the diagnosis as crescentic glomerulonephritis with massive immunoglobulin a (iga) deposition, which has never been reported in ns cases following allo-bmt. most of the massive infiltrated cells in the interstice were cd3(+)cd4(-)cd8(+) t cells derived from the donor. we observed mesangial deposition of haemophilus ...	2003	12543867
haemophilus parainfluenzae: an underdiagnosed pathogen of biliary tract infections?	presented here is a case of monobacterial peritonitis complicating cholecystitis and caused by an uncommon agent of gastrointestinal infections, haemophilus parainfluenzae. the pathogenic role of this organism in digestive infections, particularly in those of the biliary tract, has been reported increasingly though sporadically. indeed, it has been shown to be a coloniser of the gastrointestinal tract, and a recent hypothesis of an ascending route of infection to the biliary tract has been postu ...	2004	14669072
etiological agents of lower respiratory tract infections in japanese children.	to investigate the etiology of pediatric community-acquired pneumonia and bronchitis, we conducted a prospective, population-based study covering the total population < 15 years of age in 16 municipalities in hokkaido, japan, during the period of april 2000 to march 2001. chest radiographs were available for all cases (n = 921; 398 as pneumonia and 523 as bronchitis) and paired sera for serologic assays were available for more than half of the cases. the following specimens were also collected: ...	2004	15011754
antimicrobial susceptibility of haemophilus influenzae, haemophilus parainfluenzae and moraxella catarrhalis isolated from adult patients with respiratory tract infections in four southern european countries. the arise project.	over a 7-month period in 2000-2001, 1213 haemophilus influenzae, 112 haemophilus parainfluenzae and 142 moraxella catarrhalis isolates were recovered from adult patients with respiratory tract infections. patients were from four southern european countries (spain, italy, portugal and greece). the antimicrobial susceptibility of the isolates to 11 antibiotics was determined in a central laboratory. the most active drugs on the basis of mics were levofloxacin, cefditoren, cefotaxime, cefpodoxime a ...	2004	15164972
pacemaker lead infection secondary to haemophilus parainfluenzae.	cardiac device infections are a rare complication of pacing and defibrillator therapy. the number of implanted devices will likely continue to rise with increasing implantation of the cardioverter defibrillator and cardiac resynchronization devices. this report describes a case of an uncommon pathogen for device-associated endocarditis.	2004	15271026
[piercing and tattoos in patients with congenital heart disease -- is it a problem?].	piercing and tattooing enjoy widespread popularity in modern society. patients with congenital heart disease are at elevated risk for infective endocarditis. however, it is not yet known whether piercing and tattooing are dangerous for these patients.a search of the literature provided 10 published cases of infective endocarditis after piercing or tattooing. affected patients were adolescents or young adults ranging in age from 13 to 30 years (5 male, 5 female). four of the patients had a known ...	2004	15338148
["actinobacillus and haemophilus parainfluenzae infective endocarditis: two case reports"].		2004	15363627
emergence and persistence of macrolide resistance in oropharyngeal flora and elimination of nasal carriage of staphylococcus aureus after therapy with slow-release clarithromycin: a randomized, double-blind, placebo-controlled study.	to investigate the effect of slow-release (sr) clarithromycin on colonization and the development of resistance in oropharyngeal and nasal flora, a double-blind, randomized, placebo-controlled trial was performed with 8 weeks of follow-up. a total of 296 patients with documented coronary artery disease were randomized in the preoperative outpatient clinic to receive a daily dose of sr clarithromycin (500 mg) (cl group) or placebo tablets (pb group) until the day of surgery. nose and throat swabs ...	2004	15504839
population pharmacokinetics and pharmacodynamics of garenoxacin in patients with community-acquired respiratory tract infections.	garenoxacin (t-3811me, bms-284756) is a novel, broad-spectrum des-f(6) quinolone currently under study for the treatment of community-acquired respiratory tract infections. this analysis assessed garenoxacin population pharmacokinetics and exposure-response relationships for safety (adverse effects [ae]) and antimicrobial activity (clinical cure and bacteriologic eradication of streptococcus pneumoniae and the grouping of haemophilus influenzae, haemophilus parainfluenzae, and moraxella catarrha ...	2004	15561855
infection of haemophilus parainfluenzae in tonsils is associated with iga nephropathy.	we investigated the functions of tonsillar mononuclear cells (tmc) regarding whether a haemophilus parainfluenzae (hp) outer membranes antigen (hpom) enhances iga-related cytokine (ifn-gamma, il-10. and tgf-beta) production in vitro by tmc in iga nephropathy (igan) patients. in addition, we examined the effect of synthetic oligodeoxynucleotide and hpom stimulation by tmc on iga production, whether the constant region antisense to iga inhibits the production of iga in vitro by tmc. eighteen patie ...	2004	15768791
[tasks and prospects for the development of pediatric neurosurgery].		2004	525131
wildrid beric beauvais southwell, t.d., l.d.s.		2004	356861
adverse health effects of smoking and the occupational environment.		2004	516371
quantitative evidence for the helicoid relationship between the maxillary and mandibular occlusal surfaces.	a method for measuring the transverse inclination of molar teeth is described which enabled significant differences (p less than 0.001) between the three molars to be demonstrated for a sample of english modern (n 24) and romano-british (n20) skulls. no significant differences between the transverse molar inclinations were found for the bronze age (n 10) or the neanderthal (n 8) sample.	2004	321732
[interpretation of mathematical method used in prognosis of pneumonia in young children].		2004	523226
information processing in imagination using nonverbalizable visual stimuli.	in groups of 20 to 25, 146 undergraduates were tested as to their ability to mentally combine two shapes. they were to pick the correct choice from 5, 7, 9, 11, 13, or 15 alternatives. the shapes were previously proven to be effectively unverbalizable but recognizable and discriminable. contrary to expectation, there was no negative decrement in performance with increasing numbers of incorrect alternatives.	2004	514768
renal and gastric hamartomas.	this report documents a patient with renal tumor which was originally diagnosed as "wilms' tumor" and treated by irradiation and chemotherapy. fifteen years later the patient was found to have gastric hamartomas. reviews of the kidney tumor revealed it to be composed of morphologic features consistent with renal hamartoma rather than wilms' tumor. we wish to report this extremely unusual association of renal and gastric hamartomas.	2004	517500
the lateral angiogram in the differentiation of extracerebral hematomas.	the pathophysiology of epidural hematomas is considerably different from that of subdural hematomas. epidural hematomas are well-localized intracranial masses under high pressure, whereas subdural hematomas are more widespread collections of blood under lower pressure. the underlying small cortical vessels are normal in both acute and chronic subdural hematomas but are severely distorted in epidural hematomas. the appearance of these vessels, seen best in the lateral projection, can help differe ...	2005	1153776
[diagnosis of chronic hepatitis].		2005	1168784
research utilization by staff nurses: successful strategies.		2005	1490230
biologic and analytic components of variation of concentration values of selected serum proteins.	the magnitude and statistical significance of the various biologic and analytic sources of variation of the serum concentration values of seven proteins: albumin, alpha1-antitrypsin, transferrin, orosomucoid, igg, igm, and iga, were evaluated in 12 healthy subjects. blood specimens were obtained at 0800 h, 1100 h, and 1400 h on one particular day. the analytic error was partitioned into pre-instrumental and instrumental components; the biologic variation was separated into inter-subject variatio ...	2005	1087452
"morbakka", another cubomedusan.	there is a large member of the cubomedusan family, which has not yet been formally identified, that is very similar to tamoya haplonema. it is present in indo-pacific tropical waters but is also present in colder australian waters. a case of severe envenomation in south queensland is discussed and its clinical and histological features are described. vinegar inactivates the undischarged nematocysts of this species and is recommended as the initial first-aid treatment.	2005	2870414
"morbakka", another cubomedusan.	there is a large member of the cubomedusan family, which has not yet been formally identified, that is very similar to tamoya haplonema. it is present in indo-pacific tropical waters but is also present in colder australian waters. a case of severe envenomation in south queensland is discussed and its clinical and histological features are described. vinegar inactivates the undischarged nematocysts of this species and is recommended as the initial first-aid treatment.	2005	2870414
diphtheria toxin: membrane interaction and membrane translocation.		2005	1550860
diphtheria toxin: membrane interaction and membrane translocation.		2005	1550860
recruiting and retaining minority students in health sciences training programs.		2005	1195416
[ambulatory treatment of menstrual disorders after menarche].		2005	1169125
choice of diagnostic tests.		2005	1142328
[genetics of endogenous psychoses].	as the endogeneous psychoses do not show a mendelian mode of inheritance, empirical risk figures have to be calculated. they are heterogeneous and nurture as well as nature have a share in the manifestation of illness. the genetic basis of the schizophrenias is demonstrated by twin and adoption studies. the concordance rate in monozygotic twins is four times the rate in dizygotic twins. schizophrenia is to be found in the biological families of schizophrenic adoptees but not in the adoptive fami ...	2005	555545
[leeches (hirudinea) of the jamno lake].		2005	538920
[diagnosis and treatment of excessive intravascular coagulation].		2005	1251562