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pulsatile flow changes in the anterior cerebral arteries in infants with patent ductus arteriosus: measured with doppler technique.cerebral hemodynamics were measured, using the doppler ultrasound technique (directed toward anterior cerebral artery through the anterior fontanel), in 6 patent ductus arteriosus (pda) patients with large left to right shunt and in 32 neonates before and just following functional closure of ductus arteriosus. pda was confirmed by color echocardiogram and doppler flow study. all 6 sick babies had prominent retrograde flow in the descending aorta during diastole. the value of pulsatility index (p ...20092700277
[cataract surgery 220 years ago].the author reports on the first 14 cataract extractions performed by karl kaspar von siebold, a würzburg surgeon, in 1766/67. he used daviel's method. at that time there was no anesthesia, no sterility or even antisepsis, and no optical correction of aphakia for his patients. four eyes were lost due to infection and another four had much poorer vision after surgery due to irregular corneal scarring. in six cases both patient and physician were satisfied with the result. siebold's case reports ex ...20092689768
genotypes and adhd. 20092738016
[ultrasonic tissue characterization of parotid tumors--analysis with the acoustic microscope].the purpose of this study was to investigate acoustic properties of parotid tumors in detail by using the mechanically scanned acoustic microscope. the frequency of ultrasound was fixed at 200mhz. the amplitude images and the phase contrast images were taken in pictures. mean attenuation, mean velocity, microscopic variation of the attenuation and that of the sound velocity were also measured and analyzed. the results are summarized as follows: 1) the acoustic properties of the tissue were optic ...20092681618
lead toxicity and iron deficiency in utah migrant children.we determined the frequency of presumptive iron deficiency and lead toxicity in 198 utah migrant children, ages 9-72 months, during the summer of 1985. there were no confirmed cases of lead toxicity. thirteen per cent of those tested and 30 per cent of the children ages 9-23 months were iron deficient. hematocrit determinations accurately predicted iron deficiency in only 35 per cent of the children confirmed to have this disorder via erythrocyte protoporphyrin screening.20092650572
[coagulation and fibrinolytic system of macrophages]. 20092786578
emergence of drawing devices for total and partial occlusion: a longitudinal study.the developmental emergence of two drawing devices was investigated in young children: the use of omission (ie not drawing any of a hidden object) to depict total occlusion and the use of hidden line elimination (hle, ie deleting only that part of an object that is hidden from view) to depict partial occlusion in a three-dimensional scene. three groups of school children (5, 6, and 7 years old) were tested individually with two tasks four times over a 2-year period. one task called for the omiss ...20092813021
emergence of drawing devices for total and partial occlusion: a longitudinal study.the developmental emergence of two drawing devices was investigated in young children: the use of omission (ie not drawing any of a hidden object) to depict total occlusion and the use of hidden line elimination (hle, ie deleting only that part of an object that is hidden from view) to depict partial occlusion in a three-dimensional scene. three groups of school children (5, 6, and 7 years old) were tested individually with two tasks four times over a 2-year period. one task called for the omiss ...20092813021
new findings in anxiety. a synthesis for clinical practice in 1985.antidepressant therapy for panic attacks, exposure therapy for stimulus-dependent anxieties, and, to a lesser extent, clomipramine therapy for obsessive-compulsive symptoms have transformed the treatment of anxiety disorders and ushered in an era of rapid progress in research on anxiety and anxiety disorders. in most cases, these symptomatic treatments should be recommended first. after these approaches have produced maximal benefit, other treatments can be considered if indicated.20092859578
[clinical significance of the quantification of obesity. the quetelet index and its use].the degree of obesity, ie. the quantity of excessive stored adipose tissue, affects substantially morbidity and mortality on cardiovascular, metabolic, and other diseases. while the quantity of an adipose tissue is practically impossible to determine, it is necessary to use the body weight, adjusted for the stature. the quetelet's index (body mass index, bmi) is the best one from height-weight indices. values of bmi define categories of normal weight, overweight, and obesity, which have differen ...20092790909
[the role of the nurse in starting beta-blocker therapy]. 20092865817
animals released. 20092725649
chiasmal compression caused by a catheter in the suprasellar cistern. 20093285696
sonographic and pathological staging of patients with clinically localized prostate cancer.we evaluated 64 patients with clinically localized prostate cancer (on the basis of rectal examination, serum acid phosphatase, bone scan and pelvic computerized tomography scan) by transrectal sonography before radical prostatectomy. of the 48 patients with histologically proved localized prostate cancer sonography overstaged the disease in 5 (10%) and correctly staged it in 43 (90%). all overstaged cancer patients were scanned after either prostatic biopsy (4) or transurethral prostatectomy (1 ...20092681836
regulation of plasminogen activators and their inhibitors in rheumatic diseases: new understanding and the potential for new directions.over the past several years there has been a rapid expansion in our understanding of the fibrinolytic system. this includes knowledge of the components, availability of recombinant reagents and a better understanding of the regulation of fibrinolysis in health and disease. disturbances in the regulation of the balance between fibrin deposition and removal have been implicated in a number of inflammatory diseases including certain rheumatic diseases. this overview summarizes our knowledge of the ...20092681762
car radiator burns: a report on 72 cases.seventy-two cases of car radiator burns (crb) were treated in the burns unit, hamad medical corporation, doha, qatar, over a 6-year period (1982-87). all the patients were males and most were between 20 and 40 years old. chest wall, face and right upper limb were the commonest sites involved. most of the patients suffered from relatively minor scalds. the scenario of the accidents as well as the topography of the burned areas were characteristic to this particular type of injury. the exceptional ...20092765150
chronic subdural haematoma after spinal anaesthesia. case report.in this study an interesting and not frequent case of non-traumatic chronic subdural haematoma after spinal anaesthesia is reported. after a careful review of the cases described in the literature, the authors discussed the physiopathological mechanisms, emphasizing how the break of the bridge veins or of the subarachnoid granulations, the cerebral atrophy and the dehydration are factors which facilitate the appearance of this neurological complication. they suggest that a suitable post-operativ ...20094093803
chronic subdural haematoma after spinal anaesthesia. case report.in this study an interesting and not frequent case of non-traumatic chronic subdural haematoma after spinal anaesthesia is reported. after a careful review of the cases described in the literature, the authors discussed the physiopathological mechanisms, emphasizing how the break of the bridge veins or of the subarachnoid granulations, the cerebral atrophy and the dehydration are factors which facilitate the appearance of this neurological complication. they suggest that a suitable post-operativ ...20094093803
the secret of medical management.a review of the research on group practices punctures the myth of physician autonomy in hospitals and opens the way for administrators to join in controlling the patient care process.20092670836
structure-activity study of the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-induced neurotoxicity. ii. evaluation of the biological activity of the pyridinium metabolites formed from the monoamine oxidase-catalyzed oxidation of mptp analogs.in the accompanying paper, several tetrahydropyridine analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) were screened for their abilities to be oxidized by monoamine oxidase (mao) to pyridiniums and to produce neurotoxicity in mice. we reported that most of the analogs were oxidized by mao to pyridiniums and some of the analogs were neurotoxic. we concluded that the capacity of a tetrahydropyridine mptp analog to be oxidized by mao to a pyridinium was a necessary, but not sufficient ...20092786565
midazolam in the intensive care unit. 20103769775
biological markers of suicide risk and adolescent suicide. 20102905935
studies on the effects of pharmacological agents on antigen-induced arthritis in balb/c mice.the model of antigen-induced monoarticular arthritis in balb/c mice, originally described by brackertz et al. (1), has been examined with regard to disease pathogenesis and the activities of established antirheumatic agents. the acute phase of the arthritis, up to 7 days after intra-articular (ia) challenge, was characterized by intense polymorphonuclear leukocyte infiltration into the challenged joint, synovial lining cell hypertrophy and hyperplasia, accumulation of mononuclear cells within th ...20102890505
molecular neurobiology--a conference sponsored by the nimh. 20102902686
alterations in the proliferative response of t cells from aged and chimeric mice.factors involved in the nonspecific and specific proliferative responses of t cells were examined in the a/j strain of mice that were physiologically aged in the specific pathogen-free condition. in aged a/j mice, the production of il-1 and il-2 from optimally stimulated peritoneal macrophages and splenic t cells was significantly decreased, while the production of il-3 by t cells was increased. t cells from old mice showed a higher threshold for concanavalin a stimulation for the induction of i ...20102953684
levobunolol for the long-term treatment of glaucoma.systemically, levobunolol is as effective as propranolol for cardiovascular indications, with a greater potency and greater duration of action. ocularly, levobunolol is as effective and as safe as topical timolol for the long-term treatment of elevated iop. the utility of topical levobunolol as an additional, effective beta-blocker for the treatment of glaucoma will be determined by additional research and use by ophthalmologists in countries where levobunolol is approved.20103019819
levobunolol for the long-term treatment of glaucoma.systemically, levobunolol is as effective as propranolol for cardiovascular indications, with a greater potency and greater duration of action. ocularly, levobunolol is as effective and as safe as topical timolol for the long-term treatment of elevated iop. the utility of topical levobunolol as an additional, effective beta-blocker for the treatment of glaucoma will be determined by additional research and use by ophthalmologists in countries where levobunolol is approved.20103019819
cyclophosphamide, doxorubicin and cisplatin chemotherapy for patients with locally advanced urothelial tumors with or without nodal metastases.thirty-eight patients with primary urothelial tumors recurring in the pelvis or nodal presentation were treated with intravenous or intra-arterial cyclophosphamide, doxorubicin and cisplatin chemotherapy. the 38 patients were selected owing to unresectability by local criteria (12 patients) or by virtue of nodal metastases (26 patients). histologically, the patients either had pure transitional cell carcinoma (29), transformation to a histological subtype of transitional cell carcinoma (7) or pu ...20102993671
[fibrinolytic therapy of thromboembolic vascular occlusions: experiences based on 87 patients]. 20102974192
ciprostene in patients with peripheral vascular disease (pvd). an open-label, tolerance trial.epoprostenol (prostacyclin) has been studied with various success in patients with peripheral vascular disease (pvd). we investigated the tolerance of a new, stable prostacyclin derivative ciprostene (9-beta-methyl carbacyclin) in 9 pvd patients. the drug was infused intravenously for 8 hours a day, once a week for 4 consecutive weeks, at a dose of 120 ng/kg/min. there were 6 men and 3 women with a mean age of 63 years (42-78). the pvd was verified by arteriography (9 patients) and by clinical f ...20103068680
blood coagulability and viper envenomation. 20102869321
exposure to benzodiazepines in utero. 20102884529
the hypothalamic-pituitary-adrenal axis in depression. 20103035885
[use of prostacyclin in patients with ischemic stroke. a double-blind method ii].thirty patients with acute ischaemic stroke were allocated randomly into a group treated with prostacyclin and a group receiving placebo. the treatment was started 24 to 72 hours after the onset of stroke. prostacyclin sodium (wellcome, u.k. or chinoin, hpr) or its solvent (glycine buffer) were administered intravenously once daily during 2 weeks in 6-hour infusions. prostacyclin was infused at rates of 2.5-5.0 ng/kg/min. statistically significant improvement appeared from the second day on in t ...20103067105
congenital adrenal hyperplasia. 20102887945
post-translational processing of anglerfish islet somatostatin precursors.two distinct somatostatin precursors are synthesized in anglerfish (af) islets. in addition to a precursor which has somatostatin 14 (ss-14) as a c-terminal cleavage product, a precursor which contains at its c-terminus [tyr7, gly10] ss-14 as a potential cleavage product is also synthesized. however, even though an arg-lys pair is located immediately n-terminal to ala1 of the c-terminal tetradecapeptide, [tyr7, gly10]ss-14 was not found in significant amounts in extracts of af islets. instead, a ...20102863927
[creatinine clearance in the elderly. comparison of results obtained by different methods of evaluation]. 20102950506
[atypical variant of cushing's syndrome]. 20102897495
carbohydrate structures of nonspecific cross-reacting antigen-2, a glycoprotein purified from meconium as an antigen cross-reacting with anticarcinoembryonic antigen antibody. occurrence of complex-type sugar chains with the gal beta 1----3glcnac beta 1----3gal beta 1----4glcnac beta 1----outer chains.nonspecific cross-reacting antigen-2 (nca-2) is a glycoprotein purified from meconium as a closely correlated entity with carcinoembryonic antigen (cea). as in the case of cea, only asparagine-linked sugar chains are included in nca-2. in order to elucidate the structural characteristics of the sugar chains of nca-2, they were quantitatively released from the polypeptide backbone by hydrazinolysis and reduced with nab3h4 after n-acetylation. the radioactive oligosaccharides were fractionated by ...20102808357
communicating leveled clinical expectations to nursing students.nurse educators agree on the need for objectives in the classroom situation and frequently communicate them in a written form. written expectations for clinical, however, are rarely given to student nurses prior to their clinical experience. clinical expectations are understood by instructors, but communicating them to students result in mixed interpretations. the article describes the development of a written method of communicating clinical expectations to solve this problem. this method corre ...20103035139
some analyses of forgetting of pictorial material in amnesic and demented patients.three experiments evaluating the rate of forgetting of pictorial stimuli in amnesic, demented, and normal control subjects are reported. when prolonged exposures of pictorial material were used to equate recognition performance after a 10-min delay, alcoholic korsakoff (ak) patients and patients with huntington's disease (hd) demonstrated normal rates of forgetting over a 1-week period. in addition to replicating previous findings with ak patients, these results are consistent with recent sugges ...20102941450
antiprotease capacity in acute pancreatitis.serial measurements of circulating antiproteases were carried out on 42 consecutive patients admitted with acute pancreatitis. in the 7 days following admission the serum levels of alpha 1 antitrypsin (alpha 1 at), alpha 1 antichymotrypsin (alpha 1 act) and the trypsin inhibitory capacity (tic) increased by more than 300 per cent. the serum concentration of alpha 2 macroglobulin (alpha 2 m) alone showed a decline which was most profound in those patients with severe acute pancreatitis. initial e ...20103768647
neuron-specific enolase in the diagnosis of small-cell lung cancer with pleural effusion: a negative report.we measured the concentration of neuron-specific enolase (nse) and carcinoembryonic antigen (cea) in the serum and pleural fluid of 53 patients with pleural effusions, including seven patients with small-cell lung cancer (sclc). high levels (above 12.5 micrograms.l-1) of nse in pleural fluid were observed in five patients with sclc (sensitivity 71%). however, pleural fluid nse levels were also increased in five patients with other types of cancer and in four patients with non-malignant inflammat ...20102853080
arginine-dependent acid-resistance pathway in shigella boydii.ability to survive the low ph of the human stomach is considered be an important virulent determinant. it was suggested that the unique acid tolerance of shigella boydii 18 cdph, the strain implicated in a 1998 outbreak, may have played an important role in surviving the acidic food (bean salad). the strain was capable of inducing arginine-dependent acid-resistance (adar) pathway. this pathway was assumed to be absent in shigella sp. here, we have examined occurrence and efficacy of adar pathway ...201021136041
effect of nacl on the biofilm formation by foodborne pathogens.this study was designed to evaluate the effect of nacl on the biofilm formation of listeria monocytogenes, staphylococcus aureus, shigella boydii, and salmonella typhimurium. the biofilm cells were cultured in media containing different nacl concentrations (0% to 10%) for 10 d of incubation at 37 °c using a 24-well polystyrene microtiter plate, collected by swabbing methods, and enumerated using plate count method. the attachment and detachment kinetic patterns were estimated according to the mo ...201021535614
immobilization of bacteriophages on modified silica particles.bacteriophages are selective anti-bacterial agents, which are receiving increasing acceptance by regulatory agencies for use both in the food industry and in clinical settings for biocontrol. while immobilized phage could be particularly useful to create antimicrobial surfaces, current immobilization strategies require chemical bioconjugation to surfaces or more difficult processes involving modification of their head proteins to express specific binding moieties, for example, biotin or cellulos ...201019945158
combined effects of probiotic fermentation and high-pressure extraction on the antioxidant, antimicrobial, and antimutagenic activities of deodeok (codonopsis lanceolata).this study was designed to evaluate the combined effects of probiotic fermentation and high-pressure extraction (hpe) on the functional properties of codonopsis lanceolata. the ground c. lanceolata samples were anaerobically fermented with lactobacillus acidophilus adh, bifidobacterium longum b6, lactobacillus rhamnosus gg, or lactobacillus paracasei at 37 degrees c for 10 days and subjected to 500 mpa at 50 degrees c for 30 min. the extraction yields of c. lanceolata samples were noticeably inc ...201020000575
new enterovirulent escherichia coli serogroup 64474 showing antigenic and genotypic relationships to shigella boydii 16.studies based on the analysis of housekeeping genes indicate that escherichia coli and all shigella species, except for shigella boydii type 13, belong to a single species. this study analysed the phenotypic and genotypic characteristics of 23 e. coli strains isolated in different countries from faecal specimens taken from children with diarrhoea. strains were identified using the vitek system and typed with rabbit sera obtained against 186 somatic and 53 flagellar e. coli antigens and against 4 ...201020075111
characterisation of multidrug-resistant salmonella typhimurium 4,[5],12:i:- dt193 strains carrying a novel genomic island adjacent to the thrw trna locus.in 2006, monophasic, multidrug-resistant salmonella enterica spp. enterica serovar 4,[5],12:i:- strains appeared as a novel serotype in germany, associated with large diffuse outbreaks and increased need for hospitalisation. the emerging 4,[5],12:i:- strains isolated from patients in germany belong mainly to phage type dt193 according to the anderson phage typing scheme for s. typhimurium (stm) and exhibit at least a tetra-drug resistance. the strains have been shown to harbour stm-specific gifs ...201020303825
bacteriological and parasitological assessment of food handlers in the omdurman area of sudan.pathogenic organisms are thought to be widely distributed among food handlers. this study was designed to assess the prevalence of carriers of some pathogenic bacteria and intestinal parasites among food handlers in the city of omdurman, sudan.201020434126
phenotypic characterization and genomic analysis of the shigella sonnei bacteriophage sp18.a novel bacteriophage that infects shigella sonnei was isolated from the gap river in korea, and its phenotypic and genomic characteristics were investigated. the virus, called sp18, showed morphology characteristic of the family myoviridae, and phylogenetic analysis of major capsid gene (gp23) sequences classified it as a t4-like phage. based on host spectrum analysis, it is lytic to s. sonnei, but not to shigella flexneri, shigella boydii or members of the genera escherichia and salmonella. py ...201020437154
the type iii effectors nlee and nleb from enteropathogenic e. coli and ospz from shigella block nuclear translocation of nf-kappab p65.many bacterial pathogens utilize a type iii secretion system to deliver multiple effector proteins into host cells. here we found that the type iii effectors, nlee from enteropathogenic e. coli (epec) and ospz from shigella, blocked translocation of the p65 subunit of the transcription factor, nf-kappab, to the host cell nucleus. nf-kappab inhibition by nlee was associated with decreased il-8 expression in epec-infected intestinal epithelial cells. ectopically expressed nlee also blocked nuclear ...201020485572
antibacterial properties of essential oils and methanol extracts of sweet basil ocimum basilicum occurring in bangladesh.the antibacterial potential of essential oils and methanol extracts of sweet basil ocimum basilicum l. (lamiaceae) was evaluated for controlling the growth range of food-borne pathogenic bacteria. essential oils extracted by hydrodistillation from the leaves and stems were analyzed by gc-ms. fifty-seven compounds representing 94.9 and 96.1% of the total leaf and stem oils, respectively, were identified, of which methyl chavicol (36.7 and 29.9%), gitoxigenin (9.3 and 10.2%), trimethoquinol (10.3 ...201020645791
research progress in shigella in the postgenomic era.gram-negative, facultative intracellular anaerobes of the genus shigella, the principal etiologic agents of shigellosis, continue to pose a threat to public health. shigellosis causes 1.1 million deaths with over 164 million annual cases. the shigella spp. can be divided into four serogroups: shigella dysenteriae, shigella flexneri, shigella boydii and shigella sonnei. the completion of seven shigella genome sequences of representative strains from each of the shigella species has introduced an ...201021046319
biochemical characterization of udp-gal:glcnac-pyrophosphate-lipid β-1,4-galactosyltransferase wfed, a new enzyme from shigella boydii type 14 that catalyzes the second step in o-antigen repeating-unit synthesis.the o antigen is the outer part of the lipopolysaccharide (lps) in the outer membrane of gram-negative bacteria and contains many repeats of an oligosaccharide unit. it contributes to antigenic variability and is essential to the full function and virulence of bacteria. shigella is a gram-negative human pathogen that causes diarrhea in humans. the o antigen of shigella boydii type 14 consists of repeating oligosaccharide units with the structure [→6-d-galpα1→4-d-glcpaβ1→6-d-galpβ1→4-d-galpβ1→4-d ...201021057010
[antibacterial antibodies in human immunoglobulins and sera: past and present].to measure levels of several types of antibacterial antibodies in preparations of normal human immunoglobulin as well as in samples of donor sera obtained in 1965 and 2009.201021061576
the escherichia coli o149 rfb gene cluster and its use for the detection of porcine e. coli o149 by real-time pcr.pcr or hybridization assays are widely used for the identification and detection of various escherichia coli serogroups and serotypes. this study explored this approach for the detection of e. coli o149 in pigs, a dominant serogroup among those associated with porcine post-weaning diarrhea (pwd) worldwide. for this purpose, we sequenced the o antigen (rfb) gene cluster of a representative enterotoxigenic e. coli (etec) o149:h10 strain and identified a 2kbp region specific for the o149 rfb gene c ...201019733452
effects of probiotic fermentation on the enhancement of biological and pharmacological activities of codonopsis lanceolata extracted by high pressure treatment.this study was designed to evaluate the enhancement of antioxidant, antimicrobial, enzymatic, cytotoxic, and cognitive activities of codonopsis lanceolata extracted by high pressure treatment followed by probiotic fermentation. dried c. lanceolata samples were subjected to 400mpa for 20min and then fermented with bifidobacterium longum b6 (hpe-blf) and lactobacillus rhamnosus (hpe-lrf) at 37°c for 7days. compared to conventional extraction (ce-nf, 6.69mg gae/g), the phenol amounts of hpe-blf and ...201121543255
a shigella boydii bacteriophage which resembles salmonella phage vii.abstract: background: lytic bacteriophages have been applied successfully to control the growth of various foodborne pathogens. sequencing of their genomes is considered as an important preliminary step to ensure their safety prior to food applications. results: the lytic bacteriophage, phisbom-ag3, targets the important foodborne pathogen, shigella. it is morphologically similar to phage vii of salmonella enterica serovar typhi and a series of phages of acinetobacter calcoaceticus and rhizobium ...201121595934
lipopolysaccharide core structures and their correlation with genetic groupings of shigella strains; a novel core variant in shigella boydii type 16.bacteria shigella, the cause of shigellosis, evolved from intestinal bacteria escherichia coli. based on structurally diverse o-specific polysaccharide chains of the lipopolysaccharides (o-antigens), three from four shigella species are subdivided into multiple serotypes. the central oligosaccharide of the lipopolysaccharide called core is usually conserved within genus but five core types called r1-r4 and k-12 have been recognized in e. coli. structural data on the shigella core are limited to ...201121752864
neurological manifestations of shigellosis in children in southwestern iran. 201122115119
Atypical Shigella boydii 13 encodes virulence factors seen in attaching and effacing Escherichia coli.Enterohemorrhagic E. coli (EHEC) is a foodborne pathogen that causes watery diarrhea and hemorrhagic colitis. In this study, we identified StcE, a secreted zinc metalloprotease that contributes to intimate adherence of EHEC to host cells, in culture supernatants of atypical Shigella boydii 13 (Shigella B13) strains. Further examination of the Shigella B13 strains revealed that this cluster of pathogens does not invade but forms pedestals on HEp-2 cells similar to EHEC and enteropathogenic E. col ...201122126649
convergent synthesis of the tetrasaccharide repeating unit of the o-antigen of shigella boydii type 9.a convenient synthesis of the tetrasaccharide repeating unit of the o-antigen of shigella boydii type 9 has been achieved in excellent yield using a [2 + 2] block glycosylation strategy. tempo-mediated selective oxidation of the primary alcohol of the tetrasaccharide derivative 8 to the carboxylic group followed by deprotection of the functional groups furnished target tetrasaccharide 1 as its 4-methoxyphenyl glycoside in high yield.201121977201
[Etiological aspects of acute gastroenteritis--a ten-year review (1.01. 2001-31.12.2010)].Acute gastroentritis is one of the most common diseases in humans, and continues to be a significant cause of morbidity worldwide.201122046776
emergence of a novel shiga toxin-producing escherichia coli o serogroup cross-reacting with shigella boydii type 10.this is the first report of the isolation of shiga toxin-producing escherichia coli (stec) strains whose o antigens were genetically and serologically identical to those of shigella boydii type 10, from human feces. the novel stec o serogroup may be widespread in japan and associated with diarrhea and hemorrhagic colitis.201121865424
a comparison of disease caused by shigella and campylobacter species: 24 months community based surveillance in 4 slums of karachi, pakistan.despite the efforts of the international community diarrheal diseases still pose a major threat to children in children less than five years of age. bacterial diarrhea has also emerged as a public health concern due to the proliferation of drug resistant species in many parts of the world. there is a paucity of population-based data about the incidence of shigellosis and campylobacter infections in pakistan. we report country specific results for shigella diarrhea that were derived from a multic ...201121338955
genetic diversity and antibiotic resistance in shigella dysenteriae and shigella boydii strains isolated from children aged <5 years in egypt.summarydiversity within shigella dysenteriae (n=40) and shigella boydii (n=30) isolates from children living in egypt aged <5 years was investigated. shigella-associated diarrhoea occurred mainly in summer months and in children aged <3 years, it commonly presented with vomiting and fever. serotypes 7 (30%), 2 (28%), and 3 (23%) accounted for most of s. dysenteriae isolates; 50% of s. boydii isolates were serotype 2. s. dysenteriae and s. boydii isolates were often resistant to ampicillin, chlor ...201121470441
dissemination of ndm-1 positive bacteria in the new delhi environment and its implications for human health: an environmental point prevalence study.not all patients infected with ndm-1-positive bacteria have a history of hospital admission in india, and extended-spectrum β-lactamases are known to be circulating in the indian community. we therefore measured the prevalence of the ndm-1 gene in drinking water and seepage samples in new delhi.201121478057
a unique arabinose 5-phosphate isomerase found within a genomic island associated with the uropathogenicity of escherichia coli cft073.previous studies showed that deletion of genes c3405 to c3410 from pai-metv, a genomic island from escherichia coli cft073, results in a strain that fails to compete with wild-type cft073 after a transurethral cochallenge in mice and is deficient in the ability to independently colonize the mouse kidney. our analysis of c3405 to c3410 suggests that these genes constitute an operon with a role in the internalization and utilization of an unknown carbohydrate. this operon is not found in e. coli k ...201121498648
[results of conservative treatment of congenital dislocation of the hip--significance of arthrography].to evaluate the clinical value of hip arthrography, especially two-directional arthrography, the author compared the treatment results of three different groups, group a: cases treated without arthrography, group b: cases treated using anteroposterior arthrography and group c: cases treated using two-directional arthrography. with lorenz's method, all three groups achieved about 40% success to g-i, ii by severin's classification. g-iii, iv was obtained in group a, b and c at 50.4%, 19.5% and 2.8 ...20113249093
[results of conservative treatment of congenital dislocation of the hip--significance of arthrography].to evaluate the clinical value of hip arthrography, especially two-directional arthrography, the author compared the treatment results of three different groups, group a: cases treated without arthrography, group b: cases treated using anteroposterior arthrography and group c: cases treated using two-directional arthrography. with lorenz's method, all three groups achieved about 40% success to g-i, ii by severin's classification. g-iii, iv was obtained in group a, b and c at 50.4%, 19.5% and 2.8 ...20113249093
ultrastructure of the sperm and spermatogenesis and spermiogenesis of dina lineata (hirudinea, erpobdellidae).the mature sperm of dina lineata is of the modified type. the sperm are 48 micron long and 0.3 micron wide. the sperm are filiform and helicoidal cells with a distinct head, a midpiece, and a tail. there are two distinct regions in the head: the acrosome and the posterior acrosome, each with its own characteristic morphology. the midpiece is the mitochondrial region and has a single mitochondrion. two distinct portions can be observed in the tail: the axonematic region and the terminal piece. in ...20113209181
[rectosigmoid diffuse cavernous hemangioma]. 20113187159
cleavage lines of the oral mucosa in japanese cadavers.cleavage lines were experimentally reproduced in the oral mucosa of japanese cadavers. they were investigated macroscopically and histologically. the reproduced cleavage lines showed little directional variation by sex or age. from the histological findings, the mucosal cleavage lines were interpreted to represent cleavage split along the direction of connective tissue fibres in the lamina propria.20113165386
progestins and oral contraceptive-induced lipoprotein changes: a prospective study.in order to determine the effects on plasma lipoproteins of oral contraceptives containing progestins with varying androgenic potency, 136 healthy women were randomized into 3 groups and followed prospectively for one year while receiving either 50 mcg ethinyl estradiol and 1.0 mg ethynodiol diacetate (eed), 50 mcg ethinyl estradiol and 1.0 mg norethindrone acetate (ena), or 50 mcg ethinyl estradiol and 0.5 mg d-1 norgestrel (eng). comparison was made to a self-selected group of 50 women using a ...20113096633
ultrasound in the diagnosis of splenic abscess. case report. 20113071730
radiation therapy with and without chemotherapy in the treatment of localized unresectable pancreatic carcinoma. a retrospective analysis. 20113611960
botulinum toxin a-induced protective ptosis in corneal disease.botulinum toxin a produces a temporary, flaccid ptosis when injected into the levator palpebrae superioris muscle. the resulting protective ptosis was used to aid healing in 21 cases of indolent ulceration, and, prophylactically, in 4 cases of neuroparalytic keratitis. of the indolent ulcers, 90% healed completely. in all but one case, the cornea was covered completely by the lid and complete ptosis was produced in 75% of cases in an average of 3.6 days, lasting for 16 days on average before rec ...20113050691
[periarthritis of the shoulder. symptomology and classification]. 20113187101
parkinsonian rigidity: the first hundred-and-one years 1817-1918. 20113550860
parkinsonian rigidity: the first hundred-and-one years 1817-1918. 20113550860
[occupational asthma in the food industry]. 20113067294
[primary transport of acute patients. optimal use of rescue resources exemplified by the canton of graubünden]. 20113927607
using computers to take patient histories. 20113147730
perforations of the tympanic membrane following the use of goode-type 'long term' tympanostomy tubes.a retrospective review of 64 goode 't' tube insertions is presented. these were inserted into 61 ears of 48 patients over a period of four years. at the time of review of these 61 ears, 34 tubes were found to be in situ, 27 had extruded spontaneously and three had been removed surgically. ten ears in which the tube had been extruded or removed had central perforations of the tympanic membrane of which eight had been present for more than six months. the number of previous myringotomies or gromme ...20113209952
biphasic radiation-sensitivity of the transplantation immunity for rejection of an allogeneic ascites tumor.transplantation immunity for second-set rejection of an allogeneic ascites tumor was induced by sensitizing mice with h-2-identical allogeneic spleen cells, and radiation-sensitivity of this immunity was studied. the immunity was not severely affected by 400 rads whole-body x-ray irradiation given at one day before the initial antigenic stimulation. in contrast, it was totally inactivated by 300-400 rads irradiation that was given one day before tumor challenge. an adoptive cell transfer experim ...20113042613
nodular hyperplasia of brunner's glands.a clinical, endoscopic, and histological study of 206 cases of nodular hyperplasia of brunner's glands was carried out. firm nodules with a reddened surface due to hyperplastic brunner's glands were limited mainly to the first part of the duodenum and affected almost exclusively male patients. gastric acid secretion after pentagastrin stimulation was significantly increased compared to normal. in most cases, biopsies of the nodule center revealed spreading of brunner's glands from within the lam ...20114076734
interferon alpha-2b as therapy for ph'-positive chronic myelogenous leukemia: a study of 82 patients treated with intermittent or daily administration.the authors treated a total of 82 patients with ph'-positive chronic myelogenous leukemia (cml) with recombinant interferon alpha-2b (ifn alpha-2b). sixty-five patients in chronic phase (cp), 28 of whom were untreated and 37 pretreated, and nine patients in accelerated phase (ap), were started on ifn three times a week. patients in cp were randomized to receive 2 or 5 x 10(6) iu/m2, while patients in ap were all given the dose of 5 x 10(6) iu/m2, in addition to concomitant chemotherapy. patients ...20113165298
[academic dissertations of military pharmacists on the history of pharmacy]. 20113067684
an assessment of postoperative oxygen therapy in patients with fractured neck of femur.arterial oxygen tension was studied in sixty patients with fractured neck of femur. the mean preoperative arterial oxygen tension was 63.7 mmhg (sd 12.8). half of the patients received nasal oxygen for five days postoperatively. in these patients, mean arterial oxygen tension was greater at all times than preoperative values, and exceeded values in those not receiving oxygen in whom no change in oxygen tension occurred until an increase on the fifth postoperative day.20113232798
[continuing education. 28. subject: community nursing and administration. topic: the planning of changes in a primary care course]. 20113187333
tuberoinfundibular dopaminergic function in parkinson's disease.a deficit of nigrostriatal, mesocortical and mesolimbic dopamine systems in parkinson's disease is well known. we know less about the involvement of tuberoinfundibular dopamine (tid) systems. in untreated (naive or wash-out) men with parkinson's disease, we studied tid function through basal and stimulated plasma levels of growth hormone, prolactin and thyrotropin. only minor abnormalities in prolactin responses to thyrotropin-releasing hormone were found, probably reflecting denervation hyperse ...20113133213
aids policy development within the department of defense. 20113100984
office evaluation and management of the shoulder impingement syndrome.the shoulder impingement syndrome is the most common cause of shoulder pain. a complete office evaluation can be aided by a printed exam sheet. careful consideration of the differential diagnosis is important, often employing the xylocaine injection test. the impingement syndrome responds to conservative treatment the majority of the time. long follow-up determines the need for an invasive evaluation or surgical treatment.20113050719
effects of cost sharing on physiological health, health practices, and worry.in a randomized trial of the effects of medical insurance on spending and the health status of the nonaged, we previously reported that patients with limited cost sharing had approximately one-third less use of medical services, similar general self-assessed health, and worse blood pressure, functional far vision, and dental health than those with free care. of the 20 additional measures of physiological health studied here on 3,565 adults, people with cost sharing scored better on 12 measures a ...20113119520
intra-ocular pressure changes during rapid sequence induction of anaesthesia. a comparison between thiopentone and suxamethonium and thiopentone and atracurium.the changes in intra-ocular pressure associated with two different anaesthetic induction and tracheal intubation techniques were compared (n = 30). after pre-oxygenation, group a received thiopentone (5 mg/kg) followed by suxamethonium (1.5 mg/kg), both within 25 seconds, and group b atracurium (0.5 mg/kg) followed by thiopentone (5 mg/kg) again both within 25 seconds. tracheal intubation occurred after one minute in group a and 2 minutes in group b to allow for full paralysis. in group a intra- ...20113232776
the endocrine responses to general anesthesia. 20113049390
fiscal responsibility: prescription for survival. 20113121705
proteins of cervical mucus. 20124174289
focal dermal hypoplasia syndrome (goltz syndrome): the first dental case report. 20123466146
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