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neurologic complications associated with influenza a in children during the 2003-2004 influenza season in houston, texas.our objectives were to (1) describe the clinical characteristics of and viruses isolated from patients who presented with neurologic symptoms associated with influenza a infection and were hospitalized at texas children's hospital during october and november 2003 and (2) to raise awareness of the neurologic complications of influenza among us children.200415520093
genetic diversity of human pathogenic members of the fusarium oxysporum complex inferred from multilocus dna sequence data and amplified fragment length polymorphism analyses: evidence for the recent dispersion of a geographically widespread clonal lineage and nosocomial origin.fusarium oxysporum is a phylogenetically diverse monophyletic complex of filamentous ascomycetous fungi that are responsible for localized and disseminated life-threatening opportunistic infections in immunocompetent and severely neutropenic patients, respectively. although members of this complex were isolated from patients during a pseudoepidemic in san antonio, tex., and from patients and the water system in a houston, tex., hospital during the 1990s, little is known about their genetic relat ...200415528703
quantitative trait locus determining dietary macronutrient intakes is located on human chromosome 2p22.obesity is generally accompanied by increased food intake.200415531694
cloning matters: how lawrence v. texas protects therapeutic research. 200415536913
texas health and human services realign. 200415543842
breathless in houston: a political ecology of health approach to understanding environmental health concerns.a political ecology approach to the study of environmental health problems can provide a comprehensive analytical framework with which to understand geographical and social disparities in health status. to date, however, political ecology has remained limited in its application to health problems, and where health has been addressed, biomedical models have prevailed, with little attention to differing explanatory models of health and disease. by integrating political ecology with an interpretive ...200415545091
the effect of fever, febrile illnesses, and heat exposures on the risk of neural tube defects in a texas-mexico border population.hyperthermia produces neural tube defects (ntds) in a variety of animal species. elevated maternal body temperatures may also place the developing human embryo at risk. we examined the relation between maternal hyperthermia and the development of ntds in a high-risk mexican-american population.200415468073
west nile virus activity--united states, august 11-17, 2004.during august 11-17, a total of 194 cases of human west nile virus (wnv) illness were reported from 17 states (alabama, arizona, california, colorado, florida, illinois, louisiana, maryland, minnesota, mississippi, missouri, new mexico, ohio, south dakota, texas, utah, and virginia).200415318160
the "safer choices" intervention: its impact on the sexual behaviors of different subgroups of high school students.to measure the relative impact of a school-based human immunodeficiency virus (hiv)-, sexually transmitted disease (std)-, and pregnancy-prevention intervention on sexual risk-taking behaviors of different subgroups of students.200415581523
vaccinate yourself. 200417236304
protective order upheld against man for intentional hiv exposure. 200515884144
status of oral rabies vaccination in wild carnivores in the united states.persistence of multiple variants of rabies virus in wild chiroptera and carnivora presents a continuing challenge to medical, veterinary and wildlife management professionals. oral rabies vaccination (orv) targeting specific carnivora species has emerged as an integral adjunct to conventional rabies control strategies to protect humans and domestic animals. orv has been applied with progress toward eliminating rabies in red foxes (vulpes vulpes) in western europe and southern ontario, canada. mo ...200515896404
incidence of associated events during the performance of invasive procedures in healthy human volunteers.metabolic investigations often utilize arteriovenous sampling and muscle biopsy. these investigations represent some risk to the subject. we examined 369 studies performed in the general clinical research center between january 1994 and may 2003 for events related to femoral catheterization and muscle biopsies. incidents were further examined by age (younger: 18-59 yr, n=133; and older: 60-76 yr, n=28). there were no clinically defined major complications associated with either procedure. the in ...200515563628
shiga-toxigenic escherichia coli o157:h7 infections among livestock exhibitors and visitors at a texas county fair.we report an agricultural fair-associated shiga-toxigenic escherichia coli o157:h7 (stec o157) outbreak that was unusual in that it affected both livestock exhibitors and visitors. twenty-five human cases of stec o157 infection were detected after the fort bend county fair in rosenberg, texas, which ran from 9/26/03 to 10/04/03. seven cases were culture-confirmed. there were four hemolytic uremic syndrome (hus) cases, and one thrombotic thrombocytopenic purpura (ttp) case. cases ranged in age fr ...200516011437
trichinella pseudospiralis from a wild pig in texas.in december 2001, the routine inspection of a wild boar intended for human consumption revealed the presence of trichinella ssp. larvae. biological, morphological and genetic analyses demonstrated the parasite to be trichinella pseudospiralis. this is the second report of t. pseudospiralis in the united states and the first report of the parasite in a food animal species in the u.s.200515990234
vancomycin-resistant enterococcus faecium strains isolated from community wastewater from a semiclosed agri-food system in texas.vancomycin-resistant enterococcus faecium strains (vre) were isolated from human wastewater but not swine fecal waste from a semiclosed agri-food system in texas. forty-nine vre isolates possessed vana, and one possessed vanb. twenty-one pulsed-field gel electrophoresis types were identified and segregated into three groups. there was evidence of clonal dissemination among geographically separated sites.200516189128
baby doe redux? the department of health and human services and the born-alive infants protection act of 2002: a cautionary note on normative neonatal practice.the born-alive infants protection act (baipa), passed by congress in 2002, has attracted little publicity. its purposes were, in part, "to repudiate the flawed notion that a child's entitlement to the protections of the law is dependent on whether that child's mother or others want him or her." understood as antiabortion rhetoric, the bill raised little concern among physicians at the time of legislative hearings and passed in both houses by overwhelming majorities, hardly suggesting contentious ...200516199687
patient speaking: hospice patients discuss their care.much research examines the effects of hospice assistance on the primary caregivers of hospice patients, but very little systematic research has investigated the perceptions of hospice patients themselves of the care they receive. this researcher asked 38 hospice patients whether and how hospice provided comfort, allowing the patients to guide discussion of services. patients reported that hospice helped them by providing human contact, allowing open discussion and communication with other health ...200515853091
perchlorate and iodide in dairy and breast milk.perchlorate inhibits iodide uptake and may impair thyroid and neurodevelopment in infants. recently, we unambiguously identified the presence of perchlorate in all seven brands of dairy milk randomly purchased from grocery stores in lubbock, tx. how widespread is perchlorate in milk? perchlorate in 47 dairy milk samples from 11 states and in 36 human milk samples from 18 states were measured. iodide was also measured in a number of the samples. perchlorate was detectable in 81 of 82 samples. the ...200515871231
cardiorespiratory fitness and body mass index as predictors of cardiovascular disease mortality among men with diabetes.questions remain as to whether higher levels of cardiorespiratory fitness, a measure of regular physical activity, are associated with lower risk of cardiovascular disease (cvd) mortality in overweight and obese individuals with diabetes. our objective was to quantify the independent and joint relations of cardiorespiratory fitness (hereafter, fitness) and body mass index (bmi; calculated as weight in kilograms divided by the square of height in meters) with cvd mortality in men with diabetes.200516217001
promoting graduate student interest and participation in human gross anatomy.for many years, graduate students at the university of north texas health science center (unthsc) were reluctant to enroll in dissection-based human gross anatomy courses. furthermore, few graduate faculty mentors would allow their students to enroll in these courses. the significant amount of time allotted to courses such as anatomy and its effect on students' research programs have been identified by faculty as the primary reason for this lack of enthusiasm. for example, prior to 1999, graduat ...200515898079
west nile virus isolation in human and mosquitoes, mexico.west nile virus has been isolated for the first time in mexico, from a sick person and from mosquitoes (culex quinquefasciatus). partial sequencing and analysis of the 2 isolates indicate that they are genetically similar to other recent isolates from northern mexico and the western united states.200516229779
varicella vaccination of children in the united states: assessment after the first decade 1995-2005.live attenuated varicella vaccine (strain oka) was approved for administration to healthy children in the united states in 1995. over the past 10 years, varicella vaccine has been given to millions of children, usually at ages between 12 and 18 months. in states such as california, michigan, and texas, there has been a marked decline in the number of reported cases of varicella. furthermore, there has been a 75% decrease in varicella-related hospitalizations across the united states, as well as ...200515911422
decision making for hiv prevention planning: organizational considerations and influencing factors.the purpose of this cdc-funded project was to better understand how behavioral data were used in hiv prevention community planning, and use this knowledge to develop and evaluate tools for increasing the use of data in hiv prevention planning. hiv prevention community planning represents one of many efforts, in a variety of health and human service areas, to formulate plans and policies that are evidence-based and reflective of community input. the attention to evidence-based planning and the in ...200515933825
evolution of the behavioral sciences branch of the space medicine and health care systems office at the johnson space center.this paper presents a brief history of psychology and psychiatry roles in psychological selection and how these roles have evolved into the behavioral sciences branch at the johnson space center usc), houston, tx. since the initial selection of the mercury seven, the first united states astronauts, psychologists and psychiatrists have been involved in astronaut selection activities. initially very involved in psychological selection of astronauts, the role of behavioral health specialists waned ...200515943192
long-term personality data collection in support of spaceflight and analogue research.this is a review of past and present research into personality and performance at the university of texas (ut) human factors research project. specifically, personality trait data collected from astronauts, pilots, antarctic personnel, and other groups over a 15-yr period is discussed with particular emphasis on research in space and space analogue environments. the ut human factors research project conducts studies in personality and group dynamics in aviation, space, and medicine. current stud ...200515943204
multi-team dynamics and distributed expertise in imission operations.the evolution of space exploration has brought an increased awareness of the social and socio-technical issues associated with team performance and task coordination, both for the onboard astronauts and in mission control. spaceflight operations create a unique environment in which to address classic group dynamics topics including communication, group process, knowledge development and sharing, and time-critical task performance. mission operations in the early years of the 21st century have de ...200515943207
exposure. hiv-positive biter's guilty plea upheld on appeal. 200516276600
the link between the insecticide heptachlor epoxide, estradiol, and breast cancer.given the suspected effects of estrogens on breast cancer, xenoestrogenic insecticides may be a risk factor. studies of the weak xenoestrogen, 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (dde), have failed to demonstrate a causal relationship, though another estrogenic organochlorine insecticide, dieldrin, belonging to the cyclodiene family, has recently been linked to breast cancer. other cyclodienes such as heptachlor epoxide (he) and oxychlordane (oc) present in breast tissue have not been e ...200515770527
widespread rash in a man with leukemia. 200515675120
criminal exposure. mouth of hiv-positive inmate deemed a deadly weapon. 200515744886
detection of bk virus and simian virus 40 in the urine of healthy children.seroprevalence studies indicate that most primary infections with bk virus (bkv) and jc virus (jcv) occur in the first and second decades of life, respectively. relatively little is known about the transmission of these agents, including the primary source of human exposure, the portal of entry, and the pathophysiology of life-long viral persistence. we sought to determine if simian virus 40 (sv40) excretion could be detected in the urine of healthy children and to define the age-related prevale ...200515648074
geographic disparities in cervical cancer mortality: what are the roles of risk factor prevalence, screening, and use of recommended treatment?despite advances in early detection and prevention of cervical cancer, women living in rural areas, and particularly in appalachia, the rural south, the texas/mexico border, and the central valley of california, have had consistently higher rates of cervical cancer mortality than their counterparts in other areas during the past several decades.200515859052
leprosy in wild armadillos.wild nine-banded armadillos (dasypus novemcinctus) in the south central united states are highly endemic natural hosts of mycobacterium leprae. surveys conducted over the last 30 years on more than 5000 animals confirm that the infection is present among armadillos in arkansas, louisiana, mississippi and texas. highest prevalence rates are found among the animals in low-lying alluvial and coastal areas, primarily in louisiana and texas. both animal density and local factors may contribute to the ...200516248207
chimpanzees are indifferent to the welfare of unrelated group members.humans are an unusually prosocial species-we vote, give blood, recycle, give tithes and punish violators of social norms. experimental evidence indicates that people willingly incur costs to help strangers in anonymous one-shot interactions, and that altruistic behaviour is motivated, at least in part, by empathy and concern for the welfare of others (hereafter referred to as other-regarding preferences). in contrast, cooperative behaviour in non-human primates is mainly limited to kin and recip ...200516251965
texas' community health workforce: from state health promotion policy to community-level practice.imagine yourself in texas as a newly arrived immigrant who does not speak english. what would you do if your child became ill? how would you find a doctor? when you find one, will the doctor speak your native language or understand your culture? in a state of approximately 22 million people, many texas residents, marginalized by poverty and cultural traditions, find themselves in this situation. to help them, some communities across texas offer the services of promotores, or community health wor ...200516263046
toxic epidermal necrolysis associated with denileukin diftitox (dab389il-2) administration in a patient with follicular large cell lymphoma.denileukin diftitox (dab(389)il-2 or ontak) is a synthetic fusion protein with demonstrated efficacy in a number of lymphoproliferative disorders, including non-hodgkin's lymphoma. we report the case of a 45-year-old man with progressive follicular large cell lymphoma following an autologous stem cell transplant treated with denileukin diftitox who developed a fatal skin rash associated with extensive erythema, edema and large bullae involving his entire body. the clinical features and pathology ...200516263585
using ecological models in research on health disparities.ecological models of human interaction can be used to study complex community problems that affect health disparities. these models allow researchers to study the components of a problem and understand how the problem can be ameliorated with nursing interventions. this article describes four research studies in which ecological models were used to either understand a phenomenon or design and test an intervention. the methods used were ethnography, descriptive/correlational, and quasi-experimenta ...200516061168
corin gene minor allele defined by 2 missense mutations is common in blacks and associated with high blood pressure and hypertension.the natriuretic peptide system contributes to blood pressure regulation. atrial and brain natriuretic peptides are cleaved into smaller biologically active molecules by corin, a transmembrane serine protease expressed in cardiomyocytes.200516216958
self-assessment of cultural and linguistic competence in an ambulatory health system.the university health system (uhs) leaders organized a comprehensive planning process of its ambulatory care system. as part of this planning process, uhs assessed the cultural and linguistic competence of its outpatient environment. this assessment was conducted within the context of standards outlined in the u.s. department of health & human services (2001) standards for cultural and linguistically appropriate services, using a multimethod approach. this multimethod approach included (1) a rev ...200516370125
much ado about the flu. 200517094498
texas poisonings at the beginning of the 21st century: 2000 through 2002.human exposure calls to poison centers may vary by geographic region. this investigation compared the pattern of human exposure calls to texas poison centers with calls to those in other states from 2000 through 2002. although the total number of human exposure calls increased for both texas and non-texas poison centers, the increase was twice as great for those in texas. patients in texas human exposure calls tended to be younger. texas calls were more likely to involve bites and stings, suspec ...200517094511
bayesian ranking of sites for engineering safety improvements: decision parameter, treatability concept, statistical criterion, and spatial dependence.in recent years, there has been a renewed interest in applying statistical ranking criteria to identify sites on a road network, which potentially present high traffic crash risks or are over-represented in certain type of crashes, for further engineering evaluation and safety improvement. this requires that good estimates of ranks of crash risks be obtained at individual intersections or road segments, or some analysis zones. the nature of this site ranking problem in roadway safety is related ...200515949462
prevalence of class 1 integrons and antimicrobial resistance gene cassettes among enteric bacteria found in multisite group-level cohorts of humans and swine.the prevalence of antimicrobial resistance genotypic characteristics (class 1 integrons and antimicrobial resistance gene cassettes) among commensal escherichia coli isolated from humans and swine in a semiclosed, integrated farrow-to-fork population was evaluated in a cross-sectional study. the objective of this study was to establish baseline antimicrobial resistance patterns of enteric bacteria from animals and humans within the study population; specifically, genotypic traits both unique and ...200516355844
actions and beliefs related to hepatitis b and influenza immunization among registered nurses in texas.studies indicate that roughly half of health care workers are not immunized against hepatitis b and influenza. findings from a survey of 1,000 registered nurses (rns) conducted to analyze their beliefs and actions related to immunization recommendations are reported. only 8% of the responding rns chose not to receive vaccination against hepatitis b. the primary reasons that nurses declined hepatitis b vaccination were because they were not working in nursing or did not believe they were at risk ...200515982196
rabies surveillance in the united states during 2004.during 2004, 49 states and puerto rico reported 6,836 cases of rabies in nonhuman animals and 8 cases in human beings to the cdc, representing a 4.6% decrease from the 7,170 cases in nonhuman animals and 3 cases in human beings reported in 2003. approximately 92% of the cases were in wildlife, and 8% were in domestic animals (compared with 91% and 9%, respectively, in 2003). relative contributions by the major animal groups were as follows: 2,564 raccoons (37.5%), 1,856 skunks (27.1%), 1,361 bat ...200516379626
the power of the human spirit. 200516396122
a case-control study of human papillomavirus and cervical squamous intraepithelial lesions (sil) in harris county, texas: differences among racial/ethnic groups. 200516419209
number of negative acid-fast smears needed to adequately assess infectivity of patients with pulmonary tuberculosis.to investigate the relationship between the number of negative acid-fast bacilli (afb) smear results and infectivity of pulmonary tuberculosis (tb).200516002923
human exposures to tilmicosin reported to poison centres, texas, 1998-2003.tilmicosin, or 20-deoxo-20-(3,5-dimethylpiperidin-1-yl)-desmycosin, is a macrolide antibiotic primarily utilized in livestock. this study examined 46 human exposure calls involving tilmicosin received by texas poison centres during 1998-2003. the majority (91%) of the calls were received from northern and central texas. all of the cases were unintentional exposures. the most frequent route of exposure was parenteral (48%). the majority of the patients were males (80%) and adults (84%). only 46% ...200516004193
association between sociodemographic factors and exposures and utilization of poison centers in texas, 1998-2002.this study evaluated whether selected sociodemographic factors and exposures may be associated with utilization of poison centers in texas during 1998-2002. data were obtained from the six poison centers that service the entire state. cases were all human exposures where the caller county was known. the utilization rate (calls per 1000 population) was calculated for the entire state and for each county. counties were then grouped into those with utilization rates lower than the utilization rate ...200516020174
an assessment of water quality and microbial risk in rio grande basin in the united states-mexican border region.increased reliance of urban populations on rio grande water has necessitated an expanded microbial surveillance of the river to help identify and evaluate sources of human pathogens, which could pose a public health risk. the objectives of this study were to investigate microbial and chemical water quality in rio grande water and to perform risk assessment analyses for cryptosporidium. no oocysts in any of the ten-litre samples were detected. however, the limit of detection in the water samples ...200516075945
alleles of the nramp1 gene are risk factors for pediatric tuberculosis disease.relatively little is known about the human genetics of susceptibility to common diseases caused by bacterial pathogens. tuberculosis, caused by mycobacterium tuberculosis, is a major cause of morbidity and mortality worldwide. so far, genetic studies of tuberculosis susceptibility have largely been focused on adult patients despite the fact that tuberculosis is highly prevalent among children. to study the host genetic component of pediatric tuberculosis susceptibility, we enrolled 184 ethnicall ...200516103355
association of type 2 diabetes mellitus and seroprevalence for cytomegalovirus.infection is known to play a role in type 1 diabetes, but there is a paucity of information on its role in diabetes mellitus type 2. we examined the seroprevalence of selected viruses in a group of predominantly hispanic patients with type 2 diabetes and control subjects without diabetes.200516108236
aids threat. biting shoplifter gets five years after hiv threat. 200516110526
arsenic and selenium in human hair: a comparison of five countries with and without arsenicosis.the selenium (se) content of the diet and/or selenium supplements might have an ameliorating effect on arsenic (as) toxicity as recently shown by wang et al., yang et al., and as reviewed by spallholz et al.. the underlying principles of the ameliorating effect is the complexation of se with as forming the seleno-bis (s-glutathionyl) arsinium ion excreted in bile and the complexation of se with as in tissues forming nontoxic insoluble selenides. additional protection afforded by se supplementati ...200516116245
rickettsia felis infection rates in an east texas population.murine typhus (rickettsia typhi), endemic in southern california and south texas, is maintained within a host-vector system consisting of the opossum and cat flea. in the early 1990s, a second rickettsial species, rickettsia felis, was also found to be maintained within the opossum-cat flea system and is, in fact, found more commonly than r. typhi in the opossum and cat flea. recognized as a human pathogen in 1994, r. felis causes an infection that produces symptoms indistinguishable from classi ...200516130886
folic acid calls to poison centers in texas, 1998-2003.folic acid (folacin, pteroylglutamic acid) is a monoglutamate form of the water-soluble b vitamin that is involved in the synthesis of nucleotides and amino acids and the normal maturation of red blood cells. this study describes the folic acid calls received by texas poison centers during 1998-2003. there were 650 calls involving folic acid as a single-ingredient product, of which 55.1% were human exposures. children age <6 years accounted for 80.1% of the human exposures. patients were managed ...200516138734
prevalence of hepatitis b and c in pregnant women who are infected with human immunodeficiency virus.the purpose of this study was to evaluate the prevalence of hepatitis b and hepatitis c virus co-infection among pregnant women who are infected by human immunodeficiency virus and who attend an obstetric complications prenatal clinic.200516157150
rapid hiv versus enzyme-linked immunosorbent assay screening in a low-risk mexican american population presenting in labor: a cost-effectiveness analysis.mother-to-child transmission of human immunodeficiency virus is the most common cause of pediatric human immunodeficiency virus in the united states; the centers for disease control and prevention recommendations endorse rapid human immunodeficiency virus testing for women with unknown viral status to quicken antiretroviral therapy. we compared the cost-effectiveness of oraquick (orasure technologies, bethlehem, pa) rapid testing versus enzyme-linked immunosorbent assay testing for a low-risk po ...200516157152
bivariate linkage analysis of the insulin resistance syndrome phenotypes on chromosome 7q.metabolic abnormalities of the insulin resistance syndrome (irs) have been shown to aggregate in families and to exhibit trait-pair correlations, suggesting a common genetic component. a broad region on chromosome 7q has been implicated in several studies to contain loci that cosegregate with irs-related traits. however, it is not clear whether such loci have any common genetic (pleiotropic) influences on the correlated traits. also, it is not clear whether the chromosomal regions contain more t ...200516201139
pattern of stingray injuries reported to texas poison centers from 1998 to 2004.this study examined the relationship between selected factors and all human exposures involving stingray injuries reported to texas poison centers. cases were obtained retrospectively from calls to poison centers in texas and included all reported human exposures involving stingray injuries from 1998 to 2004. the distribution of cases was determined for a variety of demographic and clinical parameters. a total of 153 cases were identified. the reported stingray injury penetrance increased during ...200516408617
population genetics of the diamondback terrapin (malaclemys terrapin).we examined the population genetic structure of the diamondback terrapins (malaclemys terrapin), within and among estuaries. based on mark-recapture studies, these estuarine turtles have high site fidelity that is likely to make them vulnerable to local extinctions. we tested if observed site fidelity of adults would be reflected in intraestuarine population genetic structure of six highly polymorphic microsatellite loci (five tetranucleotide and one dinucleotide). no evidence was found for popu ...200515723664
retrospective review of serious bacterial infections in infants who are 0 to 36 months of age and have influenza a infection.previous studies of febrile children who were 3 to 36 months of age and had clinically recognizable viral syndromes have shown low rates of concurrent bacteremia. we sought to determine the prevalence of serious bacterial infections (sbis) among children with influenza a, a viral syndrome that can be established definitively by specific tests.200515741376
structured reminiscence: an intervention to decrease depression and increase self-transcendence in older women.the purpose of this study was to assess the effect of group reminiscing on depression and self-transcendence of older women residing in an assisted living facility in southeast texas. there were two major objectives for this study. one objective was to determine if depression decreased in older women after structured reminiscence group sessions held twice weekly for a six-week period. a second objective was to determine if self-transcendence increased after structured reminiscence group sessions ...200616422738
a novel missense mutation in adrb3 increases risk for type 2 diabetes in a mexican american family.the human beta3-adrenergic receptor gene (adrb3) has been investigated as a candidate gene for diabetes-related traits in many studies. however, the results have been inconsistent so it is unclear whether variation in adrb3 is a risk factor for type 2 diabetes. we have identified a novel missense mutation of adrb3 in a single large pedigree of the san antonio family diabetes/gallbladder study (safdgs) that is located in the first transmembrane domain at amino acid 62 (ile62met). the aim of this ...200616444766
human immunodeficiency virus/acquired immune deficiency syndrome: a survey of the knowledge, attitudes, and beliefs of texas registered nurses in the 21st century.there exist few studies in the united states that examine the knowledge, attitudes, and beliefs of registered nurses regarding persons with human immunodeficiency virus and acquired immune deficiency syndrome. this information is needed to determine curriculum changes and continuing education needs.200617019278
multiple rare variants in npc1l1 associated with reduced sterol absorption and plasma low-density lipoprotein levels.an approach to understand quantitative traits was recently proposed based on the finding that nonsynonymous (ns) sequence variants in certain genes are preferentially enriched at one extreme of the population distribution. the ns variants, although individually rare, are cumulatively frequent and influence quantitative traits, such as plasma lipoprotein levels. here, we use the ns variant technique to demonstrate that genetic variation in npc1l1 contributes to variability in cholesterol absorpti ...200616449388
factors associated with vaccination of medicare beneficiaries in five u.s. communities: results from the racial and ethnic adult disparities in immunization initiative survey, 2003.to examine vaccination in seniors in the five u.s. communities of the racial and ethnic adult disparities in immunization initiative.200616460383
on estimation of vaccine efficacy using validation samples with selection bias.using validation sets for outcomes can greatly improve the estimation of vaccine efficacy (ve) in the field (halloran and longini, 2001; halloran and others, 2003). most statistical methods for using validation sets rely on the assumption that outcomes on those with no cultures are missing at random (mar). however, often the validation sets will not be chosen at random. for example, confirmational cultures are often done on people with influenza-like illness as part of routine influenza surveill ...200616556610
pattern of sildenafil calls to texas poison control centers, 1998-2004.sildenafil, a popular medication approved for the treatment of erectile dysfunction, is often misused. this study sought to describe the patterns of sildenafil calls to poison control centers in texas during 1998-2004. data on all sildenafil calls reported to the texas poison center network were analyzed. there were 628 sildenafil calls, 36% of which were human exposures and 44% were drug identifications. the number of calls increased during 1998-2003 but leveled off in 2004. the sildenafil expo ...200616574625
serum soluble leptin receptor levels and free leptin index in women with polycystic ovary syndrome: relationship to insulin resistance and androgens.to evaluate levels of soluble receptor (sob-r) and free leptin in women with polycystic ovarian syndrome (pcos) and note any relationships with insulin resistance, adiposity, and androgens. leptin is an adipokine that circulates in a free form and bound to an sob-r. only free leptin is biologically active.200616579998
detection of babesia and anaplasma species in rabbits from texas and georgia, usa.rabbits have been shown to harbor a suite of zoonotic organisms, including a babesia species, borrelia burgdorferi, and anaplasma phagocytophilum. in this study, we conducted a molecular survey for various tick-borne pathogens in three species of rabbits from texas and georgia. of 18 black-tailed jackrabbits (lepus californicus) tested from texas, six (28%) were polymerase chain reaction (pcr) positive for babesia, and nucleotide sequencing revealed two distinct species or strains. two jackrabbi ...200616584322
aerobic microorganisms associated with free-ranging bottlenose dolphins in coastal gulf of mexico and atlantic ocean waters.our abilities to assess health risks to free-ranging dolphin populations, to treat live-stranded or captive dolphins, and to evaluate the risks of disease transmission between humans and dolphins have suffered from a lack of basic information on microorganisms associated with normal, presumably healthy free-ranging individuals. in order to provide these data, we sampled free-ranging bottlenose dolphins (tursiops truncatus) off florida, texas, and north carolina during 1990-2002. blowhole and ana ...200617092884
"a new deal for the drug addict": the addiction research center, lexington, kentucky.this article describes the social organization of knowledge production in the formative moments of the substance abuse research enterprise. it describes the institutional arrangements and material conditions of a u.s. public health service laboratory that was housed in a facility run jointly with the federal bureau of prisons. the addiction research center (arc) in lexington, kentucky, was dedicated to elucidating the basic underlying mechanisms of drug addiction. the arc was housed on the rural ...200616586455
a population approach to the study of emotion: diurnal rhythms of a working day examined with the day reconstruction method.to date, diurnal rhythms of emotions have been studied with real-time data collection methods mostly in relatively small samples. the day reconstruction method (drm), a new survey instrument that reconstructs the emotions of a day, is examined as a method for enabling large-scale investigations of rhythms. diurnal cycles were observed for 12 emotion adjectives in 909 women over a working day. bimodal patterns with peaks at noon and evenings were detected for positive emotions; peaks in negative ...200616637757
a pandemic flu: not if, but when. sars was the wake-up call we slept through.if an influenza pandemic struck today, borders might close, the global economy would be severely impacted, international vaccine supplies and health are systems would be overwhelmed, and some people might panic. to limit the fallout, the industrialized world must create a detailed response strategy involving the public and private sectors. some experts feel we are overdue for a flu pandemic and the sars pandemic of 2003 could have been the wake up call to begin preparations. fortunately there is ...200616681227
epidemiology of jellyfish stings reported to poison centers in texas.this study examined the relationship between selected factors and all human exposures involving jellyfish stings reported to texas poison centers. cases were obtained retrospectively from calls to poison centers in texas and included all reported human exposures during 1998-2004 involving jellyfish stings. the distribution of cases was determined for a variety of demographic and clinical parameters. there were 423 total cases. among the cases with a known patient age, 19.8% were <6 years of age, ...200616696293
testing a nurse-tailored hiv medication adherence intervention.the relationship between patient adherence and treatment outcomes has been documented across chronic health conditions, but the evidence base for effective adherence interventions in human immunodeficiency virus (hiv) and acquired immune deficiency syndrome (aids) requires more rigorous research and reporting.200616708043
valdecoxib exposures reported to texas poison centers during 2002-2004.valdecoxib is a drug possessing anti-inflammatory and analgesic properties and acts by binding to cyclo-oxygenase-2. the objective of this study was to describe the epidemiology of valdecoxib exposures reported to texas poison centers. human valdecoxib exposures reported to six texas poison centers were identified and comparisons were made between isolated and nonisolated cases with respect to various demographic and clinical factors. of 328 human valdecoxib calls, 55% were isolated and 45% were ...200616728369
personality in its natural habitat: manifestations and implicit folk theories of personality in daily life.to examine the expression of personality in its natural habitat, the authors tracked 96 participants over 2 days using the electronically activated recorder (ear), which samples snippets of ambient sounds in participants' immediate environments. participants' big five scores were correlated with ear-derived information on their daily social interactions, locations, activities, moods, and language use; these quotidian manifestations were generally consistent with the trait definitions and (except ...200616737378
community consultation in emergency research.recent federal regulations allow for emergency research without prospective consent provided that additional protections for the subjects are provided. one of these is community consultation.200616763512
alcohol problems and health care services use in human immunodeficiency virus (hiv)-infected and hiv-uninfected veterans.although alcohol problems are common in human immunodeficiency virus (hiv)-infected patients, their impact on health care services use in hiv-infected patients is not well understood.200616849968
rabies surveillance in the united states during 2005.during 2005, 49 states and puerto rico reported 6,417 cases of rabies in nonhuman animals and 1 case in a human being to the cdc, representing a 6.2% decrease from the 6,836 cases in nonhuman animals and 8 cases in human beings reported in 2004. approximately 92% of the cases were in wildlife, and 8% were in domestic animals. relative contributions by the major animal groups were as follows: 2,534 raccoons (39.5%), 1,478 skunks (23%), 1,408 bats (21.9%), 376 foxes (5.9%), 269 cats (4.2%), 93 cat ...200617173527
ssi. disability benefits denied hiv-positive man. 200616862697
aripiprazole exposures reported to texas poison control centers during 2002-2004.aripiprazole is an oral atypical antipsychotic drug used in the treatment of schizophrenia and potentially other behavior disorders. the purpose of this study was to describe the epidemiology of aripiprazole exposures reported to texas poison control centers. human aripiprazole exposures reported to six texas poison control centers were identified and comparisons were made between isolated and nonisolated cases with respect to various demographic and clinical factors. of 280 human exposures invo ...200616864422
methylphenidate abuse in texas, 1998-2004.methylphenidate is a stimulant used in the treatment of attention deficit hyperactivity disorder in children and is subject to abuse. this study describes the patterns of methylphenidate abuse and drug identification (id) calls received by several poison control centers in texas. cases were calls involving methylphenidate received by texas poison control centers during 1998-2004. drug id and drug abuse calls were assessed by call year and geographic location. drug abuse calls were then compared ...200616728377
exposure to fumonisins and the occurrence of neural tube defects along the texas-mexico border.along the texas-mexico border, the prevalence of neural tube defects (ntds) among mexican-american women doubled during 1990-1991. the human outbreak began during the same crop year as epizootics attributed to exposure to fumonisin, a mycotoxin that often contaminates corn. because mexican americans in texas consume large quantities of corn, primarily in the form of tortillas, they may be exposed to high levels of fumonisins. we examined whether or not maternal exposure to fumonisins increases t ...200616451860
perchlorate in fish from a contaminated site in east-central texas.perchlorate, a known thyroid endocrine disruptor, contaminates surface waters near military instillations where solid fuel rocket motors are manufactured or assembled. to assess potential perchlorate exposure to fish and the human population which may feed on them, fish were collected around the naval weapons industrial reserve plant in mclennan county, tx, and analyzed for the presence of the perchlorate anion. the sampling sites included lake waco and belton lake, and several streams and river ...200615993996
investigation of texas poison center calls regarding a chlorine gas release: implications for terrorist attack toxicosurveillance.the investigation reported here was conducted to describe the pattern of calls received by the texas poison center network (tpcn) in relation to a chlorine gas release that resulted from a train collision in bexar county, texas, on june 28, 2004, and to test various methods for conducting toxicosurveillance. tpcn received a total of 42 calls; the first call was received approximately 35 minutes after the collision. calls continued for 10 days after the collision. comparison of the number of call ...200617115583
challenges and opportunities of nursing care in special-needs shelters.hurricanes katrina and rita forced many individuals along the coast of texas and louisiana to seek shelter inland. among the evacuees were residents with special needs and residents of nursing homes and group homes caring for mentally retarded and physically disabled persons. many nurses volunteered to provide health care for those in need. this article discusses challenges and opportunities that were encountered by nurses volunteering in special-needs shelters. issues related to human and physi ...200617127208
guide for herbal product use by mexican americans in the largest texas-mexico border community.use of herbal products is a very common practice among mexican americans living in the el paso, texas, region. although medicinal plants are generally assumed to be a safe and natural alternative to conventional medications, some herbal products could pose a potential health risk to the consumer. currently, only a few studies focus on herbal product use by mexican americans, and no studies have focused on its use by patients with human immunodeficiency virus (hn) living on the us-mexico border. ...200617128764
"texans are everywhere!". 200617131498
association of the ptpn22 r620w polymorphism with anti-topoisomerase i- and anticentromere antibody-positive systemic sclerosis.to determine any associations of the ptpn22 r620w single-nucleotide polymorphism (snp) with systemic sclerosis (ssc) or with anticentromere antibody (aca)-positive or anti-topoisomerase i (anti-topo i) antibody-positive ssc, in a case-control study of us white, black, hispanic, and choctaw indian individuals.200617133608
hiv-positive man denied ssa disability benefits. 200617165193
human plague--four states, 2006.plague is a zoonotic disease caused by the bacterium yersinia pestis. in 2006, a total of 13 human plague cases have been reported among residents of four states: new mexico (seven cases), colorado (three cases), california (two cases), and texas (one case). this is the largest number of cases reported in a single year in the united states since 1994. dates of illness onset ranged from february 16 to august 14; two (15%) cases were fatal. the median age of patients was 43 years (range: 13-79 yea ...200616943764
antimicrobial susceptibilities of aeromonas spp. isolated from environmental sources.aeromonas spp. are ubiquitous aquatic bacteria that cause serious infections in both poikilothermic and endothermic animals, including humans. clinical isolates have shown an increasing incidence of antibiotic and antimicrobial drug resistance since the widespread use of antibiotics began. a total of 282 aeromonas pure cultures were isolated from both urban and rural playa lakes in the vicinity of lubbock, texas, and several rivers in west texas and new mexico. of these, at least 104 were subseq ...200616950901
human west nile virus neuroinvasive disease in texas, 2003 epidemic: regional differences.arboviral diseases, such as west nile virus (wnv) epizootics, tend to be geographically unique because of the biomes that support the vector(s) and reservoir host(s). understanding such details aids in preventive efforts. we studied the 2003 epidemic of human west nile neuroinvasive disease (wnnd) in texas because it initially appeared that incidence was not uniform across regions of the state.200616978879
improving perceptions of patient care--a nursing education and nursing practice initiative.in january 2005, the university of texas medical branch (utmb) school of nursing and the utmb hospitals and clinics launched the first phase of a project to improve perceptions of patient care on the part of nursing faculty and nursing clinicians. a finding on the utmb annual employee satisfaction survey that nursing faculty and clinicians tended to rate quality of utmb patient care lower than other utmb employees provided the impetus for the initiative. when utmb colleagues noticed the findings ...200616990119
disclosure. hiv-positive man faces assault with deadly weapon charge. 200616869028
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