Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| expression and activity of a novel cathelicidin from domestic cats. | cathelicidins are small cationic antimicrobial peptides found in many species including primates, mammals, marsupials, birds and even more primitive vertebrates, such as the hagfish. some animals encode multiple cathelicidins in their genome, whereas others have only one. this report identifies and characterizes feline cathelicidin (fecath) as the sole cathelicidin in domestic cats (felis catus). expression of fecath is predominantly found in the bone marrow, with lower levels of expression in t ... | 2011 | 21533281 |
| A Salmonella Virulence Factor Activates the NOD1/NOD2 Signaling Pathway. | ABSTRACT The invasion-associated type III secretion system (T3SS-1) of Salmonella enterica serotype Typhimurium (S. Typhimurium) activates the transcription factor NF-?B in tissue culture cells and induces inflammatory responses in animal models through unknown mechanisms. Here we show that bacterial delivery or ectopic expression of SipA, a T3SS-1-translocated protein, led to the activation of the NOD1/NOD2 signaling pathway and consequent RIP2-mediated induction of NF-?B-dependent inflammatory ... | 2011 | 22186610 |
| The MgtR regulatory peptide negatively controls expression of the MgtA Mg(2+) transporter in Salmonella enterica serovar Typhimurium. | MgtR is a 30 amino acid peptide that is encoded from the mgtCBR operon. This peptide has recently been demonstrated to interact with the MgtC virulence protein and lead to MgtC degradation. In the present study, we reveal that the MgtA Mg(2+) transporter is another protein under the direct control of the MgtR peptide. Salmonella expresses the MgtA transporter only in Mg(2+) depleted conditions. We determined that the MgtR peptide limits levels of the MgtA protein at low Mg(2+) concentrations. Mg ... | 2011 | 22155249 |
| defining treatment conditions for pulsed electric field pasteurization of apple juice. | the influence of temperature and the presence of n(α)-lauroyl ethylester (ethyl lauroyl arginate, lae) on the inactivation caused by continuous pulsed electric field treatments (pef) in escherichia coli o157:h7 suspended in apple juice have been investigated to define treatment conditions applicable at industrial scale that promote an equivalent safety level when compared with thermal processing. in the range of experimental conditions investigated (outlet temperature: 20-40 °c, electric field s ... | 2011 | 21880388 |
| Survival of host-associated Bacteroidales cells and their relationship with Enterococcus spp., Campylobacter jejuni, Salmonella Typhimurium and Adenovirus in freshwater microcosms as measured by PMA-qPCR. | The ideal host-associated genetic fecal marker would be capable of predicting the presence of specific pathogens of concern. Flow-through freshwater microcosms containing mixed feces and inocula of the pathogens Campylobacter jejuni, Salmonella Typhimurium and Adenovirus were placed at ambient temperature in the presence and absence of diurnal sunlight. The total Enterococcus DNA increased during the early periods (23 h) under sunlight exposure, even though cultivable Enterococcus and DNA in int ... | 2011 | 22139002 |
| The Fur regulon in anaerobically grown Salmonella enterica sv. Typhimurium: identification of new Fur targets. | ABSTRACT: | 2011 | 22017966 |
| Survival characteristics of Salmonella enterica serovar Newport in the dairy farm environment. | Multi-drug resistant (MDR) Salmonella enterica serovar Newport (S. Newport) has established a reservoir in dairy cattle. Infected herds suffer significant mortality in both adult and young animals, posing a considerable economic loss to producers. Land application of manure from infected animals may further spread the pathogen into the agroecosystem, causing public health concerns. Previous work by our group demonstrated that the organism persisted in manure and manured soil for 6 to 10 mo under ... | 2011 | 21943774 |
| Salmonella biofilm formation on Aspergillus niger involves cellulose--chitin interactions. | Salmonella cycles between host and nonhost environments, where it can become an active member of complex microbial communities. The role of fungi in the environmental adaptation of enteric pathogens remains relatively unexplored. We have discovered that S. enterica Typhimurium rapidly attaches to and forms biofilms on the hyphae of the common fungus, Aspergillus niger. Several Salmonella enterica serovars displayed a similar interaction, whereas other bacterial species were unable to bind to the ... | 2011 | 22003399 |
| Reduction of Salmonella enterica, Escherichia coli O157:H7, and Listeria monocytogenes with electrolyzed oxidizing water on inoculated hass avocados (Persea americana var. Hass). | This study was intended to evaluate the bactericidal effect of electrolyzed oxidizing water (EOW) and chlorinated water on populations of Salmonella enterica, Escherichia coli O157:H7, and Listeria monocytogenes inoculated on avocados (Persea americana var. Hass). In the first experiment, inoculated avocados were treated with a water wash applied by spraying tap water containing 1 mg/liter free chlorine for 15 s (WW); WW treatment and then spraying sodium hypochlorite in water containing 75 mg/l ... | 2011 | 21902927 |
| genotyping of salmonella enterica serovar typhi strains isolated from 1959 to 2006 in china and analysis of genetic diversity by genomic microarray. | aim. to determine the genotype of salmonella enterica serovar typhi (s. typhi) strains in china and analyze their genetic diversity. methods. we collected s. typhi strains from 1959 to 2006 in five highly endemic chinese provinces and chose 40 representative strains. multilocus sequence typing was used to determine the genotypes or sequence types (st) and microarray-based comparative genomic hybridization (m-cgh) to investigate the differences in gene content among these strains. results. forty ... | 2011 | 22180267 |
| single nucleotide polymorphisms that differentiate two subpopulations of salmonella enteritidis within phage type. | abstract: | 2011 | 21942987 |
| salmonella enterica serotype typhimurium usurps the scaffold protein iqgap1 to manipulate rac1 and mapk signalling. | salmonella enterica serotype typhimurium invades eukaryotic cells by re-arranging the host-cell cytoskeleton. however, the precise mechanisms by which salmonella induces cytoskeletal changes remain undefined. iqgap1 (iq motif-containing gtpase-activating protein 1) is a scaffold protein that binds multiple proteins including actin, the rho gtpases rac1 and cdc42 (cell division cycle 42), and components of the mapk (mitogen-activated protein kinase) pathway. we have shown previously that optimal ... | 2011 | 21851337 |
| Characterization of Salmonella occurring at high prevalence in a population of the land iguana Conolophus subcristatus in Galápagos Islands, Ecuador. | The aim of the study was to elucidate the association between the zoonotic pathogen Salmonella and a population of land iguana, Colonophus subcristatus, endemic to Galápagos Islands in Ecuador. We assessed the presence of Salmonella subspecies and serovars and estimated the prevalence of the pathogen in that population. Additionally, we investigated the genetic relatedness among isolates and serovars utilising pulsed field gel electrophoresis (PFGE) on XbaI-digested DNA and determined the antimi ... | 2011 | 21853080 |
| [Development of modified molecular beacon based real-time PCR assay for the rapid detection of Salmonella choleraesuis and Salmonella paratyphi C]. | To develop real-time PCR assay based on modified molecular beacon for simultaneous detection of S. choleraesuis and S. paratyphi C. The established method was applied to the rapid detection of S. choleraesuis in food and stool samples of food poisoning, and then was applied to the identification of Salmonella C. | 2011 | 21861361 |
| WFDC2 is differentially expressed in the mammary gland of the tammar wallaby and provides immune protection to the mammary gland and the developing pouch young. | WAP four disulfide core domain 2 (WFDC2) is a four disulfide core (4-DSC) protein secreted in the milk of the tammar wallaby. It is comprised of two 4-DSC domains assigned domain III at the NH2-terminal end and domain II at the COOH-terminal end. The WFDC2 gene was expressed only during pregnancy, early lactation, towards the end of lactation and involution. The WFDC2 protein showed antibacterial activity against Staphylococcus aureus, Salmonella enterica and Pseudomonas aeruginosa and this acti ... | 2011 | 22024352 |
| multidrug-resistant salmonella enterica. | 2011 | 22035610 | |
| Small intestinal CD8+TCR?d+ intraepithelial lymphocytes (iIELs) are involved in bacterial clearance during Salmonella typhimurium infection. | The intestinal immune system is crucial for the maintenance of mucosal homeostasis and has evolved under the dual pressure of protecting the host from pathogenic infection and co-existence with the dense and diverse commensal organisms in the lumen. Intestinal intraepithelial lymphocytes (iIELs) are the first element of the host T cell compartment available to respond to oral infection by pathogens. This study demonstrated that oral infection by Salmonella typhimurium (S. typhimurium) promoted t ... | 2011 | 22144492 |
| two efficient methods for the conjugation of smooth-form lipopolysaccharides with probes bearing hydrazine or amino groups. i. lps activation with cyanogen bromide. | this chapter presents a conjugation method for coupling probes bearing hydrazine or primary amino groups to a smooth(s)-form lipopolysaccharide (lps). lps is modified by the activation of the hydroxyl groups present in its o-antigen moiety with cyanogen bromide in aqueous acetone. the method yields conjugates with good labeling ratios, preserving the endotoxic activity of the lipid a moiety. conjugation of smooth-form lps from salmonella enterica sv. minnesota with dansyl hydrazine and horseradi ... | 2011 | 21567325 |
| two efficient methods for the conjugation of smooth-form lipopolysaccharides with probes bearing hydrazine or amino groups. ii. lps activation with a cyanopyridinium agent. | this chapter presents a conjugation method for coupling probes bearing hydrazine or primary amino groups to a lipopolysaccharide (lps). lps is modified by the activation of the hydroxyl groups present in its o-antigen moiety with 1-cyano-4-dimethylaminopyridinium tetrafluoroborate (cdap). the method yields conjugates with good labeling ratios, preserving the endotoxic activity of the lipid a moiety. conjugation of smooth-form lps from salmonella enterica sv. minnesota with dansyl hydrazine and h ... | 2011 | 21567326 |
| Application of a bacteriophage cocktail to reduce Salmonella Typhimurium U288 contamination on pig skin. | Multidrug-resistant Salmonella Typhimurium U288 is a significant pathogen of pigs, accounting for over half of all outbreaks on UK pig production premises. The potential of this serovar, and other salmonellae, to enter the food chain during the slaughtering process requires that efforts be made to reduce the prevalence of these bacteria at both the pre- and post-harvest stages of production. A bacteriophage cocktail (PC1) capable of lysing various Salmonella enterica serovars was designed using ... | 2011 | 21899907 |
| Modification of the BAX Salmonella test kit to include a hot start functionality (modification of AOAC Official Method 2003.09). | In 2010, the BAX System PCR assay for Salmonella was modified to include a hot start functionality designed to keep the reaction enzyme inactive until PCR begins. To validate the assay's Official Methods of Analysis status to include this procedure modification, an evaluation was conducted on four food types that were simultaneously analyzed with the BAX System and either the U.S. Food and Drug Administration's Bacteriological Analytical Manual or the U.S. Department of Agriculture-Food Safety a ... | 2011 | 22165013 |
| genetic characterization of the mechanisms of resistance to amoxicillin/clavulanate and third-generation cephalosporins in salmonella enterica from three spanish hospitals. | the mechanisms of antimicrobial resistance were characterized in 90 salmonella enterica isolates either resistant or with intermediate resistance to amoxicillin/clavulanate (amc(r/i)) or resistant to third-generation cephalosporins (c3g(r)). these isolates were recovered in three spanish hospitals during 2007-2009. the c3g(r) phenotype was expressed by three isolates that carried the following extended-spectrum β-lactamase genes: phage-associated bla(ctx m-10) in s. virchow, bla(ctx-m-14a) surro ... | 2011 | 22101415 |
| Application of a 16S rRNA PCR/HRMA Assay for Rapid Detection of Salmonella Bacteremia: A Case Report. | Current culture and phenotypic protocols for diagnosing Salmonella infections can be time consuming. Here, we describe the application of a 16S rRNA PCR coupled to high resolution melt analysis for species and serotype identification in six hours of blood sample collection from a patient with Salmonella serotype Enteritidis bacteremia. | 2011 | 22205823 |
| comparison of two possible routes of pathogen contamination of spinach leaves in a hydroponic cultivation system. | the route of pathogen contamination (from roots versus from leaves) of spinach leaves was investigated with a hydroponic cultivation system. three major bacterial pathogens, escherichia coli o157:h7, salmonella, and listeria monocytogenes, were inoculated into the hydroponic solution, in which the spinach was grown to give concentrations of 10⁶ and 10³ cfu/ml. in parallel, the pathogens were inoculated onto the growing leaf surface by pipetting, to give concentrations of 10⁶ and 10³ cfu per leaf ... | 2011 | 21902924 |
| Crystallization and preliminary crystallographic analysis of an Ig-domain-encompassing fragment of the giant adhesion protein SiiE from Salmonella enterica. | Salmonella infections can be life-threatening. SiiE is a giant adhesion molecule of 5559 amino acids that is encoded in Salmonella pathogenicity island 4 (SPI4) and that promotes the initial contact between the pathogen and polarized epithelial cells in the intestine of the host. Starting from an engineered deletion version of SiiE (mini-SiiE; 97 kDa), limited proteolysis was used to reproducibly generate a 30 kDa fragment that readily crystallized. Mass spectrometry hints that this fragment spa ... | 2011 | 22102234 |
| oxysterol-binding protein (osbp) enhances replication of intracellular salmonella and binds the salmonella spi-2 effector ssel via its n-terminus. | effectors translocated into the host cell by salmonella enterica serovar typhimurium are critical for bacterial virulence. for many effectors, the mechanisms of their interactions with host pathways are not yet understood. we have recently found an interaction between the spi-2 effector ssel and oxysterol-binding protein (osbp). we show here that ssel binds the n-terminus of osbp and that s. typhimurium infection results in redistribution of osbp. we furthermore demonstrate that osbp is required ... | 2011 | 21988961 |
| Identification of environmental reservoirs of nontyphoidal salmonellosis: aptamer-assisted bioconcentration and subsequent detection of salmonella typhimurium by quantitative polymerase chain reaction. | In this study, identification of environmental reservoirs of Salmonella enterica subsp. enterica serovar Typhimurium (abbreviated as Salmonella Typhimurium) in sediments, water, and aquatic flora collected from the Ganges River (Ganges riverine material) was carried out by adopting a two-step strategy. Step 1 comprised a selective serovar-specific capture of Salmonella Typhimurium from potential reservoirs. Step 2 involved culture-free detection of selectively captured Salmonella Typhi ... | 2011 | 21875107 |
| Lrp acts as both a positive and negative regulator for type 1 fimbriae production in Salmonella enterica serovar Typhimurium. | Leucine-responsive regulatory protein (Lrp) is known to be an indirect activator of type 1 fimbriae synthesis in Salmonella enterica serovar Typhimurium via direct regulation of FimZ, a direct positive regulator for type 1 fimbriae production. Using RT-PCR, we have shown previously that fimA transcription is dramatically impaired in both lrp-deletion (?lrp) and constitutive-lrp expression (lrp(C)) mutant strains. In this work, we used chromosomal P(fimA)-lacZ fusions and yeast agglutination assa ... | 2011 | 22046399 |
| BT cationic peptides: Small peptides that modulate innate immune responses of chicken heterophils and monocytes. | Neonatal poultry exhibit a transient susceptibility to infectious diseases during the first week of life that stems from inefficient host defense mechanisms. Yet, the initial host immune response to pathogens is a critical determinant of disease resistance and susceptibility. With this context in mind, novel ways to stimulate or modulate the hosts' natural immune response is emerging as an important area of interest for food animal producers including the poultry industry. Specifically, we have ... | 2011 | 22129785 |
| inhibition of growth of highly resistant bacterial and fungal pathogens by a natural product. | the continuous escalation of resistant bacteria against a wide range of antibiotics necessitates discovering novel unconventional sources of antibiotics. b. oleracea l (red cabbage) is health-promoting food with proven anticancer and anti-inflammatory activities. however, it has not been researched adequately for its antimicrobial activity on potential resistant pathogens. the methanol crude extract of b. oleracea l. was investigated for a possible anti-microbial activity. the screening method w ... | 2011 | 21915230 |
| pulsed-field gel electrophoresis supports the presence of host-adapted salmonella enterica subsp. enterica serovar typhimurium strains in the british garden bird population. | salmonellosis is a frequently diagnosed infectious disease of passerine birds in garden habitats within great britain with potential implications for human and domestic animal health. postmortem examinations were performed on 1,477 garden bird carcasses of circa 50 species from england and wales, 1999 to 2007 inclusive. salmonellosis was confirmed in 263 adult birds of 10 passerine species in this 11-year longitudinal study. a subset of 124 fully biotyped salmonella enterica subsp. enterica sero ... | 2011 | 21948838 |
| isolation and characterization of bacteriophages of salmonella enterica serovar pullorum. | in this study, 2 bacteriophages of salmonella pullorum were isolated using an enrichment protocol and the double agar layer method. they were named pspu-95 and pspu-4-116, respectively, against clinical isolates of salmonella pullorum spu-95 and spu-116. the host ranges of the 2 bacteriophages were determined by performing spot tests with 20 bacteria strains. both bacteriophages had wide host ranges. bacteriophage pspu-95 had a lytic effect on 17 of the 20 isolates (85%), and pspu-4-116 produced ... | 2011 | 21934022 |
| Acanthamoeba polyphaga, a potential environmental vector for the transmission of food-borne and opportunistic pathogens. | The endosymbiotic relationship could represent for many bacteria an important condition favouring their spread in the environment and in foods. For this purpose we studied the behaviour of some food-borne and opportunistic pathogens (Listeria monocytogenes, Staphylococcus aureus, Enterococcus faecalis, Salmonella enterica serovar Enteritidis, Aeromonas hydrophila, Yersinia enterocolitica) when internalized in Acanthamoeba polyphaga. Our results confirm the capability of the bacteria tested to gr ... | 2011 | 21953544 |
| Three novel Anas platyrhynchos avian ß-defensins, upregulated by duck hepatitis virus, with antibacterial and antiviral activities. | Three novel Anas platyrhynchos avian ß-defensins (Apl_AvBDs), Apl_AvBD4, 7 and 12, were identified successfully and characterized in tissues from Peking ducks in the present study. The cDNA fragment of Apl_AvBD4 contained 171 bp, and encoded 56 amino acids. The complete nucleotide sequences of Apl_AvBD7 and 12 contained 204 bp and 198 bp open reading frames, which encoded 67 and 65 amino acids, respectively. Both recombinant and synthetic forms of the three Apl_AvBDs showed antibacterial activit ... | 2011 | 21856003 |
| Epidemiological characteristics and molecular typing of Salmonella enterica serovar Typhi during a waterborne outbreak in Eastern Anatolia. | In this study, we aimed to study the molecular and epidemiological characteristics of Salmonella enterica serovar Typhi (S. Typhi) outbreak in Eastern Anatolia. Six hundred and thirty-seven patients from the same county with clinical diagnosis of typhoid fever were investigated with conventional methods from stool, urine and blood specimens. Antibiotic susceptibility tests and identifications were performed for positive specimens. Clonal relationships between the isolates were investigated using ... | 2011 | 21929877 |
| phosphoproteomic analysis of salmonella-infected cells identifies key kinase regulators and sopb-dependent host phosphorylation events. | salmonella enterica is a bacterial pathogen that causes gastroenteritis and typhoid fever. virulence is achieved by two type iii secretion systems that translocate effector proteins into host cells, where they mimic or block host protein function. effectors translocated into host cells by the first type iii secretion system facilitate invasion and stimulate intracellular signaling cascades leading to inflammation. here, we performed global temporal analysis of host signaling events induced durin ... | 2011 | 21934108 |
| MLVA polymorphism of Salmonella enterica subspecies isolated from humans, animals, and food in Cambodia. | ABSTRACT: | 2011 | 21861934 |
| report of a salmonella enterica serovar typhi isolate from india producing cmy-2 ampc β-lactamase. | 2011 | 22146877 | |
| identification of salmonella enterica species- and subgroup-specific genomic regions using panseq 2.0. | the pan-genome of a taxonomic group consists of evolutionarily conserved core genes shared by all members and accessory genes that are present only in some members of the group. group- and subgroup-specific core genes are thought to contribute to shared phenotypes such as virulence and niche specificity. in this study we analyzed 39 salmonella enterica genomes (16 closed, 23 draft), a species that contains two human-specific serovars that cause typhoid fever, as well as a large number of zoonoti ... | 2011 | 22001825 |
| transcription of pattern recognition receptors and abortive agents induced chemokines in the bovine pregnant uterus. | pattern recognition receptors (prrs) are important components of the innate immune system whose ligands are specific pathogen associated molecular patterns (pamps). considering the scarcity of studies on transcription of prrs in the pregnant uterus of cows, and its response to pamps and microorganisms that cause abortion in cattle, this study aimed to characterize the transcription of tlr1-10, nod1, nod2 and md2 in bovine uterus throughout gestation and to investigate the sensitivity of differen ... | 2011 | 22153993 |
| Standardisation of multilocus variable-number tandem-repeat analysis (MLVA) for subtyping of Salmonella enterica serovar Enteritidis. | Salmonella enterica serovar (S.) Enteritidis is an important cause of food-borne infection in Europe and the United States. Further subtyping of isolates is necessary to support epidemiological data for the detection of outbreaks and identification of the vehicle of infection. Multilocus variable-number tandem-repeat analysis (MLVA) is reportedly more discriminatory and produces data that are easier to share via databases than other molecular subtyping methods. However, lack of standardisation o ... | 2011 | 21871223 |
| Reduction of Salmonella enterica serovar Choleraesuis carrying large virulence plasmids after the foot and mouth disease outbreak in swine in southern Taiwan, and their independent evolution in human and pig. | BACKGROUND/PURPOSE: Salmonella enterica serovar Choleraesuis (S. Choleraesuis) is a highly invasive zoonotic pathogen that causes bacteremia in humans and pigs. The prevalence of S. Choleraesuis in man has gradually decreased since the outbreak of foot and mouth disease in pigs in 1997 in southern Taiwan. The goal of this study was to investigate the change in prevalence of S. Choleraesuis carrying the virulence plasmid (pSCV) in human and swine isolates collected in 1995-2005 and characterize t ... | 2011 | 22209685 |
| Response surface methodology-based optimization of decontamination conditions for Escherichia coli O157:H7 and Salmonella Typhimurium on fresh-cut celery using thermoultrasound and calcium propionate. | A combination of thermoultrasound (temperature: 50, 55, 60°C; time: 10, 15, 20 min with the frequency of 40 KHz) and calcium propionate (concentration: 1, 2, 3%, w/v) treatment was applied to decontaminate Escherichia coli O157:H7 and Salmonella enterica serovar Typhimurium (S. Typhimurium) from fresh-cut celery. Using a Box-Behnken experimental design, predictive quadratic equations were developed for treatment-based population reductions of E. coli O157:H7 (R(2)=0.98, p<0.001) and S. Typhimuri ... | 2011 | 21849219 |
| A new biphenyl and antimicrobial activity of extracts and compounds from Clusia burlemarxii. | Phytochemical investigation on Clusia burlemarxii (Clusiaceae) led to isolation and identification of nine compounds. Were isolated from leaves 3-O-a-L- rhamnopyranosylquercetin, 3-O-a-L-rhamnopyranosylkaempferol, 4-hydroxy-5,5-dimethyldihydrofuran-2-one, 2Z-d-tocotrienoloic acid and friedelin and were isolated from trunk betulinic acid, protocatechuic acid, lyoniresinol, and a new biphenyl 2,2-dimethyl-3,5-dihydroxy-7-(4-hydroxyphenyl)chromane. The structures were determined by ¹H, ¹³C-NMR, DEP ... | 2011 | 21893172 |
| Regulation of biofilm components in Salmonella enterica serovar Typhimurium by lytic transglycosylases involved in cell wall turnover. | In Salmonella enterica serovar Typhimurium, a biofilm mode of growth known as the rdar morphotype is regulated by several networks which sense multiple environmental signals. The transcriptional regulator CsgD is the major target for these regulatory pathways. In this study, we show that two lytic transglycosylases of family I, MltE and MltC, in combination increase CsgD expression and rdar morphotype. MltE and MltC, which share a highly similar transglycosylase SLT domain, work redundantly to r ... | 2011 | 21965572 |
| Genome and proteome of Campylobacter jejuni bacteriophage NCTC 12673. | Campylobacter jejuni continues to be the leading cause of bacterial food-borne illness worldwide, so improvements to current methods used for bacterial detection and disease prevention are needed. We describe here the genome and proteome of C. jejuni bacteriophage NCTC 12673 and the exploitation of its receptor-binding protein for specific bacterial detection. Remarkably, the 135-kb Myoviridae genome of NCTC 12673 differs greatly from any other proteobacterial phage genome described (including C ... | 2011 | 21965409 |
| withdrawn: azithromycin for treating uncomplicated typhoid and paratyphoid fever (enteric fever). | review status: current question - no update intended. azithromycin treatments are included in the review: fluoroquinolones for treating typhoid and paratyphoid fever (enteric fever). (thaver d, zaidi akm, critchley ja, azmatullah a, madni sa, bhutta za. fluoroquinolones for treating typhoid and paratyphoid fever (enteric fever). cochrane database of systematic reviews 2008, issue 4. art. no.: cd004530. doi: 10.1002/14651858.cd004530.pub3.) this latter review is being updated, and will be publi ... | 2011 | 21975751 |
| effects of residual antibiotics in groundwater on salmonella typhimurium: changes in antibiotic resistance, in vivo and in vitro pathogenicity. | an outbreak-causing strain of salmonella enterica serovar typhimurium was exposed to groundwater with residual antibiotics for up to four weeks. representative concentrations (0.05, 1, and 100 μg l(-1)) of amoxicillin, tetracycline, and a mixture of several other antibiotics (1 μg l(-1) each) were spiked into artificially prepared groundwater (agw). antibiotic susceptibility analysis and the virulence response of stressed salmonella were determined on a weekly basis by using human epithelial cel ... | 2011 | 22051852 |
| tlr5-dependent immunogenicity of a recombinant fusion protein containing an immunodominant epitope of malarial circumsporozoite protein and the flic flagellin of salmonella typhimurium. | recently, we described the improved immunogenicity of new malaria vaccine candidates based on the expression of fusion proteins containing immunodominant epitopes of merozoites and salmonella enterica serovar typhimurium flagellin (flic) protein as an innate immune agonist. here, we tested whether a similar strategy, based on an immunodominant b-cell epitope from malaria sporozoites, could also generate immunogenic fusion polypeptides. a recombinant his6-tagged flic protein containing the c-term ... | 2011 | 21881771 |
| SadA, a trimeric autotransporter from Salmonella enterica serovar Typhimurium, can promote biofilm formation and provides limited protection against infection. | Salmonella enterica is a major cause of morbidity worldwide and mortality in children and immunocompromised individuals in sub-Saharan Africa. Outer membrane proteins of Salmonella are of significance because they are at the interface between the pathogen and the host, they can contribute to adherence, colonization, and virulence, and they are frequently targets of antibody-mediated immunity. In this study, the properties of SadA, a purported trimeric autotransporter adhesin of Salmonella enteri ... | 2011 | 21859856 |
| Prevalence and antimicrobial susceptibility of major foodborne pathogens in imported seafood. | Seafood is a leading commodity implicated in foodborne disease outbreaks in the United States. Seafood importation rose dramatically in the past 3 decades and now contributes to more than 80% of the total U.S. seafood supply. However, limited data are available on the microbiological safety of imported seafood. In this study, we obtained a total of 171 salmon, shrimp, and tilapia samples imported from 12 countries in three retail stores in Baton Rouge, LA. The total microbial population and the ... | 2011 | 21902913 |
| [immunogenicity of attenuated salmonella choleraesuis vaccine strain expressing immunogenic genes of mycoplasma hyopneumoniae in mice]. | the study was carried out to construct and characterize salmonella choleraesuis vaccine strain expressing immunogenic genes of mycoplasma hyopneumoniae and to test its immunogenicity in mice. | 2011 | 22126084 |
| Multilocus variable-number tandem-repeat analysis for subtyping Salmonella enterica serovar Gallinarum. | Salmonella enterica serovar Gallinarum causes a severe systemic disease, fowl typhoid, primarily in chickens and turkeys, and it remains a disease of worldwide significance. Multilocus variable-number tandem-repeat analysis (MLVA) has proved to be very useful for subtyping other Salmonella serovars. We describe the development of a simple MLVA assay for S. enterica serovar Gallinarum that is comparable with pulsed-field gel electrophoresis (PFGE) in resolution. The genome sequence of S. enterica ... | 2011 | 22107089 |
| Structure elucidation of the O-Antigen of Salmonella enterica O51 and its structural and genetic relation to the O-Antigen of Escherichia coli O23. | The O-polysaccharide (O-antigen) of Salmonella enterica O51 was isolated by mild acid degradation of the lipopolysaccharide and its structure was established using sugar analysis and NMR spectroscopy. The O-antigen of Escherichia coli O23, whose structure was elucidated earlier, possesses a similar structure and differs only in the presence of an additional lateral a-D-Glcp residue at position 6 of the GlcNAc residue in the main chain. Sequencing of the O-antigen gene clusters of S. enterica O51 ... | 2011 | 21999538 |
| molecular and cellular characterization of a salmonella enterica serovar paratyphi a outbreak strain and the human immune response to its infection. | enteric fever is an invasive life-threatening systemic disease caused by the salmonella enterica human adapted serovars typhi and paratyphi. increasing incidence of infections with salmonella enterica serovar paratyphi a (s. paratyphi a) and the spreading of its antibiotic-resistant derivates pose a significant health concern in some areas of the world. herein we describe a molecular and phenotypic characterization of a s. paratyphi a strain accounted for a recent paratyphoid outbreak in nepal, ... | 2011 | 22190395 |
| structural and genetic characterization of the closely related o-antigens of escherichia coli o85 and salmonella enterica o17. | o-antigen is a part of the lipopolysaccharide present in the outer membrane of gram-negative bacteria, which confers major antigenic variability to the cell surface. in this study, we report on a previously undefined pair of escherichia coli and salmonella enterica with closely related o-antigens. the o-polysaccharides were isolated from the lipopolysaccharides of e. coli o85 and s. enterica o17 by mild acid degradation and studied by sugar analysis and nmr spectroscopy. the following structure ... | 2011 | 20501518 |
| comparative virulence genotyping and antimicrobial susceptibility profiling of environmental and clinical salmonella enterica from cochin, india. | salmonella enterica serotype newport is an important cause of non-typhoidal salmonellosis, a clinically less severe infection than typhoid fever caused by s. enterica serotype typhi. in this investigation, the virulence genotypes of s. enterica newport isolated from a backwater environment were compared with salmonella typhi from clinical cases in the same region where salmonellosis is endemic. genotyping was done by pcr screening for virulence markers associated with salmonella pathogenicity is ... | 2011 | 20490498 |
| curtailed short-term and long-term survival following infection with non-typhoid salmonella in israel. | among bacterial foodborne pathogens, non-typhoid salmonella enterica (nts) is a leading cause of death worldwide. this study assessed short-term and long-term mortality following nts infection in israel, and evaluated the effects of age, sex, source of isolation and different serotypes on mortality. the source of data was a national registry of nts isolates submitted to the salmonella reference center, government central laboratories, in jerusalem, israel, during 1997-2006. vital status was deri ... | 2011 | 20132249 |
| evaluation of pet-related management factors and the risk of salmonella spp. carriage in pet dogs from volunteer households in ontario (2005-2006). | the purpose of this study was to determine pet-related management factors that may be associated with the presence of salmonella spp. in feces of pet dogs from volunteer households. from october 2005 until may 2006, 138 dogs from 84 households in ontario were recruited to participate in a cross-sectional study. five consecutive daily fecal samples were collected from each dog and enrichment culture for salmonella spp. was performed. a higher than expected number of the dogs (23.2%; 32/138) had a ... | 2011 | 20163574 |
| culture-independent quantification of salmonella enterica in carcass gauze swabs by flotation prior to real-time pcr. | to facilitate quantitative risk assessment in the meat production chain, there is a need for culture-independent quantification methods. the aim of this study was to evaluate the use of flotation, a non-destructive sample preparation method based on traditional buoyant density centrifugation, for culture-independent quantification of intact salmonella in pig carcass gauze swabs (100 cm(2)) prior to quantitative pcr (qpcr). a novel approach was investigated, excluding the homogenization step prio ... | 2011 | 20417982 |
| hemorrhagic colitis as the onset of wegener's granulomatosis. | 2011 | 20544207 | |
| peptidomic analysis of the skin secretions of the frog pachymedusa dacnicolor. | high-resolution mass spectrometry-based peptidomics has been used to characterize several components in electro-stimulated skin secretions of the endemic mexican frog pachymedusa dacnicolor. peptide mass screening performed in an orbitrap-xl mass spectrometer showed that p. dacnicolor skin secretions possess 194 different components with molecular masses ranging mainly from 500 to 6,000 da. dozens of molecules were partially sequenced including two novel protease inhibitors. additionally, one po ... | 2011 | 20352461 |
| molecular subtypes of campylobacter spp., salmonella enterica, and escherichia coli o157:h7 isolated from faecal and surface water samples in the oldman river watershed, alberta, canada. | campylobacter spp., salmonella enterica, and escherichia coli o157:h7 isolated from 898 faecal, 43 sewage, and 342 surface water samples from the oldman river were characterized using bacterial subtyping methods in order to investigate potential sources of contamination of the watershed. among these pathogens, campylobacter spp. were the most frequently isolated from faecal, sewage, and surface water samples (266/895, 11/43, and 91/342, respectively), followed by salmonella (67/898, 8/43, and 29 ... | 2011 | 20971491 |
| type vi secretion regulation: crosstalk and intracellular communication. | pathogens use type vi secretion systems (t6sss) to transport proteins into the environment or host cells in response to external stimuli. t6sss are tightly regulated together with other virulence determinants such as type iii secretion systems, quorum sensing (qs), and flagella synthesis. five pathogens (salmonella enterica, edwardsiella tarda, aeromonas hydrophila, vibrio cholerae, and pseudomonas aeruginosa) are examined for crosstalk proteins (global regulators) that connect t6sss to other vi ... | 2011 | 20971679 |
| the ubiquitin-binding adaptor proteins p62/sqstm1 and ndp52 are recruited independently to bacteria-associated microdomains to target salmonella to the autophagy pathway. | 2011 | 21079414 | |
| re-emergence of multi-drug resistant salmonella enterica serovar stanley from cattle. | during 2009, salmonella enterica subspecies enterica serovar stanley isolates were recovered from cattle diagnostic specimens in southern japan, and the isolates were examined to characterize the genetic determinants involved in this new pathogenicity that associated with mortality in cattle. all the isolates were multi-drug resistance exhibited resistance to ampicillin, chloramphenicol, streptomycin, sulfamethoxazole, oxytetracycline, and kanamycin (acssut-km) encoded by blatem, cata, aada1, su ... | 2011 | 21061061 |
| systematic review of animal models of post-infectious/post-inflammatory irritable bowel syndrome. | post-infectious irritable bowel syndrome (pi-ibs) is a subset of ibs which occurs after an episode of acute gastrointestinal infections. the mechanisms of pi-ibs are not fully understood. currently, numerous animal models have been used in the study of pi-ibs. this article reviews the strengths and weaknesses of these models. | 2011 | 20848144 |
| joint effects of topoisomerase alterations and plasmid-mediated quinolone-resistant determinants in salmonella enterica typhimurium. | alterations in topoisomerases and plasmid-mediated quinolone-resistant (pmqr) determinants have been identified as main quinolone-resistant mechanisms in salmonella enterica typhimurium. but the joint effects of these mechanisms have not been thoroughly characterized in homologous salmonella typhimurium strains. in this study, isogenic topoisomerase mutants were constructed using phage λ red recombinase system and phage transduction. and the joint effects of topoisomerase mutations (gyra [s83f], ... | 2011 | 20818995 |
| targeting tumor gene by shrna-expressing salmonella-mediated rnai. | rna interference (rnai) has been established as an important research tool that carries great potential for gene therapy. however, targeted induction of rnai in vivo has met with significant challenges. in this study, a novel psls plasmid capable of expressing short hairpin rnas (shrnas) was transformed into attenuated salmonella enterica serovar typhimurium strain 7207 (sl). in vitro infection studies with the transformed s. enterica containing psls (sl-psls-cat) demonstrated that expression of ... | 2011 | 20811467 |
| osteomyelitis in adults: an underrecognized clinical entity in immunocompetent hosts. a report of six cases. | osteomyelitis is rare in adults and typically occurs in patients with risk factors such as sickle cell disease or immune deficiency. cases in immunocompetent adults without sickle cell disease are extremely rare. the objective of this work was to describe the epidemiological, clinical, laboratory, and radiological features and the management of long-bone osteomyelitis in immunocompetent adults without sickle cell disease. | 2011 | 20800526 |
| on-farm multi-contamination of pigs by food-borne bacterial zoonotic hazards: an exploratory study. | application of risk analysis to control pork-borne zoonoses on farms is a major aim of the current european food safety legislation. the prevalence, levels of contamination and variations in pig contaminations according to herds and batches must therefore be studied to define relevant methods for control of zoonoses. the aims of this exploratory study were to provide information on the prevalence and levels of infection of finisher/fattening pigs by campylobacter spp., clostridium perfringens, l ... | 2011 | 20655671 |
| rpoe may promote flagellar gene expression in salmonella enterica serovar typhi under hyperosmotic stress. | salmonella enterica serovar typhi z66 positive strain contains a fljba-like operon on a linear plasmid. the operon contains the gene fljb:z66 which encodes the z66 antigen. rpoe is a sigma factor σ(e) that initiates transcription of a series of genes in escherichia and salmonella under environmental stresses. to investigate whether the gene fljb:z66 is regulated by rpoe (σ(e)), a rpoe deletion mutant of s. enterica serovar typhi (δrpoe) was prepared in this study. the defective motility of the δ ... | 2011 | 20717675 |
| isolation of scfv fragments specific to ompd of salmonella typhimurium. | pork meat is one of the major sources for human infections with salmonella enterica subspecies enterica serovars. further, zoonoses caused by s. enterica subspecies enterica serovars are responsible for substantial economical losses in industrial countries. quick and reliable detection of this infection is urgently needed to improve consumer security. due to its capability to identify infections independent of the species, a competitive elisa is the preferable method for the detection of anti-sa ... | 2011 | 20708859 |
| salmonella transcriptional signature in tetrahymena phagosomes and role of acid tolerance in passage through the protist. | salmonella enterica typhimurium remains undigested in the food vacuoles of the common protist, tetrahymena. contrary to its interaction with acanthamoeba spp., s. typhimurium is not cytotoxic to tetrahymena and is egested as viable cells in its fecal pellets. through microarray gene expression profiling we investigated the factors in s. typhimurium that are involved in its resistance to digestion by tetrahymena. the transcriptome of s. typhimurium in tetrahymena phagosomes showed that 989 and 12 ... | 2011 | 20686510 |
| antibacterial activity of extracts from plants of central argentina--isolation of an active principle from achyrocline satureioides. | the great increase in bacterial infections is fueling interest in the search for antibacterial products of plant origin. extracts obtained from 51 native and naturalized plants from central argentina were therefore evaluated for their in vitro inhibitory activity on pathogenic bacteria with the aim of selecting the most active ones as new sources of effective antibiotics. the susceptibility of reference and clinical strains of enterococcus faecalis, escherichia coli, proteus mirabilis, pseudomon ... | 2011 | 20645245 |
| identification and biological activity of potential probiotic bacterium isolated from the stomach mucus of breast-fed lamb. | the lactic acid bacterium e isolated from the stomach mucus of breast-fed lamb was identified by sequencing of 16s rdna fragment and species-specific pcr as lactobacillus reuteri. its potential antimicrobial activity and ability to modulate immune system in vitro and in vivo was determined. the growth inhibition of potential pathogens decreased from staphylococcus aureus, pseudomonas aeruginosa, salmonella enterica ser. minnesota to escherichia coli. the lowest inhibition activity was observed i ... | 2011 | 24031741 |
| Imaging and analysis of Pseudomonas aeruginosa swarming and rhamnolipid production. | Many bacteria spread over surfaces by "swarming" in groups. A problem for scientists who study swarming is the acquisition of statistically significant data that distinguish two observations or detail the temporal patterns and two-dimensional heterogeneities that occur. It is currently difficult to quantify differences between observed swarm phenotypes. Here, we present a method for acquisition of temporal surface motility data using time-lapse fluorescence and bioluminescence imaging. We specif ... | 2011 | 21984238 |
| Control of Salmonella enterica Typhimurium in chicken breast meat by irradiation combined with modified atmosphere packaging. | Salmonella is one of the leading causes of human foodborne illnesses originating from meat and poultry products. Cross-contamination of Salmonella from raw to cooked products continues to be problematic in the food industry. Therefore, new intervention strategies are needed for meat and poultry products. Vacuum or modified atmosphere packaging (MAP) are common packaging techniques used to extend the shelf life of meat products. Irradiation has been well established as an antibacterial treatment ... | 2011 | 22054182 |
| oral co-administration of live attenuated salmonella enterica serovar typhimurium expressing chicken interferon-α and interleukin-18 enhances the alleviation of clinical signs caused by respiratory infection with avian influenza virus h9n2. | the combined use of cytokines has shown synergistic and/or additive effects in controlling several viral infections of livestock animals. however, little is known concerning the practical use of chicken cytokine combinations to control avian diseases. here, we investigated the antiviral efficacy of oral co-administration of chicken interferon-α (chifn-α) and chicken interleukin-18 (chil-18) using attenuated salmonella enterica serovar typhimurium in chickens infected with avian influenza virus ( ... | 2011 | 22245401 |
| the antimicrobial effects of propolis collected in different regions in the basque country (northern spain). | the antimicrobial activity of 19 propolis extracts prepared in different solvents (ethanol and propylene glycol) (eep/pep), was evaluated against some bacterial and fungal isolates using the agar-well diffusion method. it was verified that all the samples tested showed antimicrobial activity, although results varied considerably between samples. results revealed that both types of propolis extracts showed highly sensitive antimicrobial action against gram-positive bacteria and fungi at a concent ... | 2011 | 22805915 |
| [detection of salmonella and mycobacterium species in seagulls captured in talcahuano, chile]. | salmonella can be isolated from the feces of seagulls. therefore these birds can be a vector for dissemination of this pathogen. | 2011 | 22446658 |
| [epidemiology, microbiology, and outcomes of septicemia in children treated at the charles de gaulle university pediatric hospital in burkina faso]. | the aim of this study is to describe the epidemiological and microbiological characteristics and outcome of children with septicemia at the charles de gaulle university pediatric hospital of ouagadougou to help improve probabilistic antibiotic therapy in this type of infection. this retrospective descriptive study covered all the children from 0 to 15 years old seen over a period of 7 years in any hospital department with suspected bacteriemia and for whom the bacteriology laboratory performed a ... | 2011 | 22407247 |
| antimicrobial and safety properties of lactobacilli isolated from two cameroonian traditional fermented foods. | twenty-one lactobacillus isolates from "sha'a" (a maize - based fermented beverage) and "kossam" (traditionally fermented cow milk) were selected in accordance with their antagonistic activities and tested for their bacteriocinogenic potential as well as safety properties. these isolates were preliminarily identified as lactobacillus plantarum (62%), lactobacillus rhamnosus (24%), lactobacillus fermentum (10%) and lactobacillus coprophilus (4%) based on phenotypic characteristics and rep-pcr gen ... | 2011 | 22396914 |
| extreme antimicrobial peptide and polymyxin b resistance in the genus burkholderia. | cationic antimicrobial peptides and polymyxins are a group of naturally occurring antibiotics that can also possess immunomodulatory activities. they are considered a new source of antibiotics for treating infections by bacteria that are resistant to conventional antibiotics. members of the genus burkholderia, which includes various human pathogens, are inherently resistant to antimicrobial peptides. the resistance is several orders of magnitude higher than that of other gram-negative bacteria s ... | 2011 | 22919572 |
| competition and resilience between founder and introduced bacteria in the caenorhabditis elegans gut. | the microbial communities that reside within the intestinal tract in vertebrates are complex and dynamic. in this report, we establish the utility of c. elegans as a model system for identifying the factors that contribute to bacterial persistence and for host control of gut luminal populations. we found that for n2 worms grown on mixed lawns of bacteria, salmonella substantially out-competed e. coli even when e. coli was initially present at 100-fold higher concentrations. to address whether in ... | 2011 | 22184417 |
| in vivo expression of salmonella enterica serotype typhi genes in the blood of patients with typhoid fever in bangladesh. | salmonella enterica serotype typhi is the cause of typhoid fever. it is a human-restricted pathogen, and few data exist on s. typhi gene expression in humans. | 2011 | 22180799 |
| The TCA cycle is not required for selection or survival of multidrug-resistant Salmonella. | OBJECTIVES: The initial aim of this study was to use a systems biology approach to analyse a ciprofloxacin-selected multidrug-resistant (MDR) Salmonella enterica serotype Typhimurium, L664. METHODS: The whole genome sequence and transcriptome of L664 were analysed. Site-directed mutagenesis to recreate each mutation was carried out, followed by phenotypic characterization and mutation frequency analysis. As a mutation in the TCA cycle was detected we tested the controversial hypothesis regarding ... | 2011 | 22186876 |
| An outbreak of Salmonella enterica serotype Choleraesuis in goitered gazelle (Gazella subgutrosa subgutrosa) and a Malayan tapir (Tapirus indicus). | An outbreak of Salmonella enterica serotype Choleraesuis enteritis occurred in two juvenile goitered gazelles and an adult Malayan tapir over a period of 5 wk at the Minnesota Zoo. Diagnosis was made postmortem on one gazelle and one tapir, and a second gazelle was diagnosed via fecal culture. The death of the tapir was attributed to S. enterica serovar Choleraesuis septicemia, while salmonellosis was considered to be a contributing factor besides ostertagiasis for the death of one goitered gaze ... | 2011 | 22204065 |
| Deletion of glucose-inhibited division (gidA) gene alters the morphological and replication characteristics of Salmonella enterica Serovar typhimurium. | Salmonella is an important food-borne pathogen that continues to plague the United States food industry. Characterization of bacterial factors involved in food-borne illnesses could help develop new ways to control salmonellosis. We have previously shown that deletion of glucose-inhibited division gene (gidA) significantly altered the virulence potential of Salmonella in both in vitro and in vivo models of infection. Most importantly, the gidA mutant cells displayed a filamentous morphology comp ... | 2011 | 22109813 |
| Salmonella bongori provides insights into the evolution of the Salmonellae. | The genus Salmonella contains two species, S. bongori and S. enterica. Compared to the well-studied S. enterica there is a marked lack of information regarding the genetic makeup and diversity of S. bongori. S. bongori has been found predominantly associated with cold-blooded animals, but it can infect humans. To define the phylogeny of this species, and compare it to S. enterica, we have sequenced 28 isolates representing most of the known diversity of S. bongori. This cross-species analysis al ... | 2011 | 21876672 |
| temperature-sensitive mutants of rnase e in salmonella enterica. | rnase e has an important role in mrna turnover and stable rna processing, although the reason for its essentiality is unknown. we isolated conditional mutants of rnase e to provide genetic tools to probe its essential function. in salmonella enterica serovar typhimurium, an extreme slow-growth phenotype caused by mutant ef-tu (gln125arg, tufa499) can be rescued by mutants of rnase e that have reduced activity. we exploited this phenotype to select mutations in rnase e and screened these for temp ... | 2011 | 21949072 |
| Handheld device for real-time, quantitative, LAMP-based detection of Salmonella enterica using assimilating probes. | A simple handheld instrument was designed to enable real-time detection of the LAMP reaction in a standard PCR tube using newly described assimilating probes as sequence-specific reporter molecules. The system was validated using DNA isolated from Salmonella enterica, demonstrating accurate temperature control with little power and little overshoot of setpoint temperatures, with rapid and accurate detection often in less than 30 min and within 20 min for reactions with high (>10(5)) genome copy ... | 2011 | 21982643 |
| binding of the ramr repressor to wild-type and mutated promoters of the rama gene involved in efflux-mediated multidrug resistance in salmonella enterica serovar typhimurium. | the transcriptional activator rama is involved in multidrug resistance (mdr) by increasing expression of the acrab-tolc rnd-type efflux system in several pathogenic enterobacteriaceae. in salmonella enterica serovar typhimurium (s. typhimurium), rama expression is negatively regulated at the local level by ramr, a transcriptional repressor of the tetr family. we here studied the dna-binding activity of the ramr repressor with the rama promoter (p(rama)). as determined by high-resolution footprin ... | 2011 | 22123696 |
| decreased transport restores growth of a salmonella enterica apbc mutant on tricarballylate. | mutants of salmonella enterica lacking apbc have nutritional and biochemical properties indicative of defects in iron-sulfur ([fe-s]) cluster metabolism. an apbc mutant is unable to grow on tricarballylate as a carbon source. based on the ability of apbc to transfer an [fe-s] cluster to an apoprotein, this defect was attributed to poor loading of the [fe-s] cluster-containing tcub enzyme. consistent with these observations, a previous study showed that overexpression of iscu, which encodes an [f ... | 2011 | 22101844 |
| Influence of prior growth conditions, pressure treatment parameters, and recovery conditions on the inactivation and recovery of Listeria monocytogenes, Escherichia coli, and Salmonella Typhimurium in turkey meat. | The relatively high prevalence of Listeria monocytogenes, Escherichia coli O157:H7, and Salmonella enterica serovar Typhimurium in various food products is of great concern to the food industry. The objective of this study was to determine the pressure-inactivation of the pathogens in a representative food model as affected by prior growth temperature, physiological age of the culture, pressure level and treatment temperature. The effect of post-treatment conditions (incubation temperature and g ... | 2011 | 22169000 |
| Salmonella enterica serovar Typhimurium and Enteritidis infection of pigs and cytokine signalling in palatine tonsils. | Pigs are considered as one of the major sources of zoonotic strains of Salmonella enterica for humans. Out of many S. enterica serovars, S. Typhimurium dominates in pigs, however, in several countries in Central Europe, S. Enteritidis is also quite frequent in pig herds. In this study we therefore compared the colonisation of pigs with S. Typhimurium and S. Enteritidis. We found that 3 weeks after infection S. Enteritidis 147 colonised the intestinal tract in higher quantities but was shed in fa ... | 2011 | 22019291 |
| distinct peripheral blood rna responses to salmonella in pigs differing in salmonella shedding levels: intersection of ifng, tlr and mirna pathways. | transcriptomic analysis of the response to bacterial pathogens has been reported for several species, yet few studies have investigated the transcriptional differences in whole blood in subjects that differ in their disease response phenotypes. salmonella species infect many vertebrate species, and pigs colonized with salmonella enterica serovar typhimurium (st) are usually asymptomatic, making detection of these salmonella-carrier pigs difficult. the variable fecal shedding of salmonella is an ... | 2011 | 22174891 |
| nanostructured silver vanadate as a promising antibacterial additive to water-based paints. | in this article, we report the use of nanostructured silver vanadate as a promising antibacterial additive to water-based paints that has potential for applications in bathrooms, kitchens, and hospital environments. this hybrid nanomaterial was prepared by a simple and fast precipitation reaction involving silver nitrate and ammonium vanadate, dismissing the hydrothermal treatment. the preparation involved using ag vanadate nanowires (β-agvo(3)) with diameters ranging from 20 to 60 nm and decora ... | 2011 | 22197722 |
| Genome sequencing reveals diversification of virulence factor content and possible host adaptation in distinct subpopulations of Salmonella enterica. | Divergence of bacterial populations into distinct subpopulations is often the result of ecological isolation. While some studies have suggested the existence of Salmonella enterica subsp. enterica subclades, evidence for these subdivisions has been ambiguous. Here we used a comparative genomics approach to define the population structure of Salmonella enterica subsp. enterica, and identify clade-specific genes that may be the result of ecological specialization. | 2011 | 21859443 |
| Empiric antimicrobial therapy and infectious diarrhea. Do we need local guidelines? | In the management of acute diarrhea, administration of antibiotics may be indicated. Appropriate antimicrobial therapy can shorten illness, reduce morbidity and can be life-saving in invasive infections. Emergence of microbial strains resistant to commonly used antibiotics means that treatment failures may become common. Because of changing patterns of resistance, knowledge of recent local patterns of susceptibility can guide the initial choice of antibiotics. | 2011 | 21925045 |