Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| clinical signs, magnetic resonance imaging features, and outcome after surgical and medical treatment of otogenic intracranial infection in 11 cats and 4 dogs. | brainstem dysfunction resulting from central extension of infection is a life-threatening complication of otitis media/interna (omi) that has been described infrequently in dogs and cats. we review the clinical signs of disease, diagnostic findings, and results of surgical and medical treatments of brainstem disease attributable to otogenic intracranial infection in cats and dogs. eleven cats and 4 dogs were examined because of acute, subacute, or chronic clinical signs of brain disease includin ... | 2006 | 16734103 |
| clonal stability of pasteurella multocida in free-range layers affected by fowl cholera. | detailed longitudinal studies of the genetic stability of pasteurella multocida ssp. multocida, the cause of fowl cholera, have not previously been carried out. consequently, the aim of the present study was to provide detailed information on the genetic stability and diversity of p. multocida ssp. multocida in poultry flocks over time, enabling new insights into the molecular epidemiology of this important poultry pathogen. longitudinal investigations of the rate and causes of mortality were ca ... | 2006 | 16595311 |
| evaluation of antigen panels for elisa monitoring of mouse colonies for antibodies to pasteurellaceae. | pasteurellaceae infection in mice may be monitored by the detection of serum antibody using enzyme-linked immunosorbent assay (elisa). we re-evaluated our standard antigen panel comprising pasteurella pneumotropica and a v-factor requiring haemophilus species (strain h21) by studying their serological relationship with actinobacillus muris and 'haemophilus influenzae-murium'. serologically, a. muris and 'h. influenzae-murium' were found to be unrelated and to differ from p. pneumotropica and hae ... | 2006 | 16600079 |
| subcellular distribution of plp-40, a lipoprotein in a serotype a strain of pasteurella multocida. | a 40-kda lipoprotein (plp-40) is expressed by serotype a strains of pasteurella multocida in amounts which correlate with the amount of capsular material present. we hypothesized that plp-40 is exposed at the outer surface of the outer membrane (om) of the cell and is associated with the serotype a exopolysaccharide material. the objectives of the present study were to confirm the lipoprotein nature of plp-40 and to determine its subcellular location. plp-40 maturation was shown to be sensitive ... | 2006 | 16735091 |
| production of a d-glycero-d-manno-heptosyltransferase mutant of mannheimia haemolytica displaying a veterinary pathogen specific conserved lps structure; development and functionality of antibodies to this lps structure. | previous structural studies of the lipopolysaccharides from the veterinary pathogens mannheimia haemolytica (mh), actinobacillus pleuropneumoniae (ap) and pasteurella multocida (pm) had identified a conserved inner core oligosaccharide structure that was present in all strains investigated. in order to examine the potential of this inner core structure as a vaccine, a mutagenesis strategy was adopted to interrupt a d-glycero-d-manno-heptosyltransferase gene (losb) of mh. this gene encodes the en ... | 2006 | 16750602 |
| respiratory problems caused by pasteurella multocida in dairy buffaloes in pakistan. | 2006 | 16751312 | |
| effect of mannheimia (pasteurella) haemolytica infection on acute-phase proteins and some mineral levels in colostrum-breast milk-fed or colostrum-breast milk-deprived sheep. | the aim of this study was to investigate the levels of acute-phase proteins and minerals as indicators for the reactivity in 1-year-old sheep. a total of 26 chios breed sheep were fed colostrum-breast milk (control, n = 15)or were deprived afterseparation from their mother immediately after birth(experimental, n = 11). mannheimia (pasteurella) haemolytica serotype a1 was inoculated intratracheally and blood samples were taken in vacuumed sera on days 0, 1, 4, 7, 10, 13, 16, 19 and 22. antibiotic ... | 2006 | 16755360 |
| endocarditis caused by pasteurella multocida. | 2006 | 16761455 | |
| tissue plasminogen activator combined with human recombinant deoxyribonuclease is effective therapy for empyema in a rabbit model. | there have been no controlled studies to test the efficacy of tissue plasminogen activator (tpa) or recombinant human deoxyribonuclease (rhdnase) in the treatment of empyema. in vitro studies show that streptokinase without rhdnase does not liquefy empyemic material from rabbits. however, the combination of streptokinase and streptodornase and rhdnase have been shown to liquefy pus in vitro. the aim of this study was to determine if tpa or rhdnase, or a combination of the two, is more effective ... | 2006 | 16778278 |
| analytical verification of a multiplex pcr for identification of bordetella bronchiseptica and pasteurella multocida from swine. | bordetella bronchiseptica and pasteurella multocida are etiologic agents of progressive atrophic rhinitis (par) and bronchopneumonia in swine. only dermonecrotic toxin-producing strains of p. multocida play a role in atrophic rhinitis while both toxigenic and nontoxigenic strains have been associated with pneumonia. monitoring and investigation of outbreaks involving these bacteria require sensitive and accurate identification and reliable determination of the toxigenic status of p. multocida is ... | 2006 | 16782287 |
| separate pathways for o acetylation of polymeric and monomeric sialic acids and identification of sialyl o-acetyl esterase in escherichia coli k1. | o acetylation at carbon positions 7 or 9 of the sialic acid residues in the polysialic acid capsule of escherichia coli k1 is catalyzed by a phase-variable contingency locus, neuo, carried by the k1-specific prophage, cus-3. here we describe a novel method for analyzing polymeric sialic acid o acetylation that involves the release of surface sialic acids by endo-n-acetylneuraminidase digestion, followed by fluorescent labeling and detection of quinoxalinone derivatives by chromatography. the res ... | 2006 | 16923886 |
| gamma-glutamylcysteine synthetase-glutathione synthetase: domain structure and identification of residues important in substrate and glutathione binding. | in most organisms, glutathione (gsh) is synthesized by the sequential action of distinct enzymes, gamma-glutamylcysteine synthetase (gamma-gcs) and gsh synthetase (gs). in streptococcus agalactiae, gsh synthesis is catalyzed by a single enzyme, gamma-glutamylcysteine synthetase-glutathione synthetase (gamma-gcs-gs). the n-terminal sequence of gamma-gcs-gs is similar to escherichia coli gamma-gcs, but the c-terminal sequence is an atp-grasp domain more similar to d-ala, d-ala ligase than to any k ... | 2006 | 16939198 |
| crystallization and preliminary crystallographic studies of the pasteurella multocida toxin catalytic domain. | the c-terminal catalytic domain of pasteurella multocida toxin, which is the virulence factor of the organism in p. multocida, has been expressed, purified and subsequently crystallized using the sitting-drop vapour-diffusion technique. native diffraction data to 1.9 a resolution were obtained at the bl44xu beamline of spring-8 from a flash-frozen crystal at 100 k. the crystals belong to space group c2, with unit-cell parameters a = 111.0, b = 150.4, c = 77.1 a, beta = 105.5 degrees, and are lik ... | 2006 | 16946476 |
| meningoencephalomyelitis caused by pasteurella multocida in a cat. | 2006 | 16955836 | |
| functional characterization of pmhs1, a pasteurella multocida heparosan synthase. | heparosan synthase 1 (pmhs1) from pasteurella multocida type d is a dual action glycosyltransferase enzyme that transfers monosaccharide units from uridine diphospho (udp) sugar precursors to form the polysaccharide heparosan (n-acetylheparosan), which is composed of alternating (-alpha4-glcnac-beta1,4-glcua-1-) repeats. we have used molecular genetic means to remove regions nonessential for catalytic activity from the amino- and the carboxyl-terminal regions as well as characterized the functio ... | 2006 | 16959770 |
| [pasteurella] caballi infection not limited to horses - a closer look at taxon 42 of bisgaard. | to investigate if taxon 42 of bisgaard isolated from pigs represents genuine [pasteurella] caballi, which was previously only isolated from horses. | 2006 | 16965374 |
| [pasteurella dagmatis spondylodiscitis in a diabetic patient]. | healthy pets contact are able to induce unusual and severe diseases. | 2006 | 16978746 |
| complications of a cat bite. | 2006 | 16988179 | |
| phylogenetic relationship of pasteurella pneumotropica isolates from laboratory rodents based on 16s rdna sequence. | a 1344 bp fragment of the 16s ribosomal dna (rdna) sequence was used to determine the genetic relationship of pasteurella pneumotropica isolates from laboratory rodents. a total of 30 nucleotide sequences of p. pneumotropica, including 24 wild strains, 3 reference strains, and 3 nucleotide sequences deposited in genbank, were examined for heterogeneity of their 16s rdna sequences. phylogenetic analysis based on 16s rdna sequence discriminated 5 types of branching lineages. of these 5 types, 3 ty ... | 2006 | 16820726 |
| development of a toxa gene knock-out mutant of pasteurella multocida and evaluation of its protective effects. | pasteurella multocida is an important veterinary and opportunistic human pathogen. in particular, strains of p. multocida serogroup d cause progressive atrophic rhinitis, and produce a potent, intracellular, mitogenic toxin known as p. multocida toxin (pmt), which is encoded by the toxa gene. to further investigate the toxigenic and pathogenic effects of pmt, a toxa-deleted mutant was developed by homologous gene recombination. when administrated to mice, the toxigenicity of the toxa mutant p. m ... | 2006 | 16820762 |
| fowl cholera outbreak in domestic poultry and epidemiological properties of pasteurella multocida isolate. | symptoms of fowl cholera including orofacial edema, swollen and edematous wattles and combs, and severe respiratory disorders were detected in domestic poultry in two broiler breeder farms: one located in gyeong-gi province (october, 2000) and the other in chung-cheong-nam province (march, 2001). gram-negative, bipolar staining bacillus was easily found in a direct smear. the biochemical properties of isolates were examined using a standard diagnosis method, proving that they were 99.7% similar ... | 2006 | 16820765 |
| characterization of a bacteriocin-like substance produced by bacillus amyloliquefaciens isolated from the brazilian atlantic forest. | a bacillus strain producing a bacteriocin-like substance was characterized by biochemical profiling and 16s rdna sequencing. phylogenetic analysis indicated that the strain has high sequence similarity with bacillus amyloliquefaciens. the antimicrobial substance was inhibitory to pathogenic and food-spoilage bacteria, such as listeria monocytogenes, bacillus cereus, serratia marcescens, and pasteurella haemolytica. it was stable over a wide temperature range, but lost activity when the temperatu ... | 2006 | 16835841 |
| [an unusual case of pulmonary granulomatous lesion in an immunocompetent patient: infection caused by pasteurella multocida]. | we report a case of lung infection caused by pasteurella multocida in an immunocompetent patient. diagnosis was made both on histological analysis of a lung wedge resection, showing pyoepithelioid granulomas, and on bacteriological cultures from lung tissue. histological diagnosis of pulmonary pasteurellosis is difficult, and other etiological causes of pyoepithelioid granulomas of the lung have to be discussed. pulmonary pasteurellosis is particularly severe in immunocompromised patients, and s ... | 2006 | 16841009 |
| diversity of temperate bacteriophages induced in bovine and ovine mannheimia haemolytica isolates and identification of a new p2-like phage. | the diversity of temperate bacteriophages was examined in 32 mannheimia haemolytica, six mannheimia glucosida and four pasteurella trehalosi isolates. phage particles were induced and identified by electron microscopy in 24 (75%) m. haemolytica isolates, but in only one (17%) m. glucosida and one (25%) p. trehalosi isolate. the m. haemolytica phages were relatively diverse as seven siphoviridae, 15 myoviridae and two podoviridae-like phages were identified; the myoviridae-type phages also exhibi ... | 2006 | 16842340 |
| pasteurella multocida pneumonia in an elderly non-immunocompromised man with a leg ulcer and exposure to cats. | 2006 | 16864021 | |
| outbreaks of avian cholera in hope bay, antarctica. | during austral summers 1999-2000 and 2000-01, two outbreaks of avian cholera occurred in the hope bay area (63 degrees 24's, 56 degrees 59'w), located on the tip of the antarctic peninsula. eighty-six dead birds were found: five kelp gulls (larus dominicanus), 36 skuas (stercorarius sp.), and 45 adelie penguins (pygoscelis adeliae). the carcasses were studied using clinical, pathological, and microbiological criteria. water samples from ponds where birds were settled and samples from 90 healthy ... | 2006 | 16870848 |
| potential pathogens carried by spanish ibex (capra pyrenaica hispanica) in southern spain. | the spanish ibex (capra pyrenaica hispanica) population of southern spain was surveyed for potential pathogens associated with the conjunctiva, external ear canal, as well as reproductive and upper respiratory tracts. we sampled 321 ibex (131 adult males, 100 adult females, and 90 yearlings); these included 271 apparently healthy animals and 50 that were naturally infected with sarcoptes scabiei. a total of 688 bacterial isolates were identified (377 gram-negatives, 225 gram-positives, and 86 my ... | 2006 | 16870855 |
| [pasteurella pneumotropica produces regression of human tumors transplanted in immunodeficiency mice]. | the technique of human tumor cell line transplantation in immunodeficient mice is used worldwide as a model for cancer research. in accordance with international recommendations, animals used in biomedical research should be free of microorganisms which can interfere in experimental results; including pasteurella pneumotropica. the object of this study was to evaluate the interference produced by p. pneumotropica in the human adenocarcinoma cell line a549 transplanted in n:nih(s)-nu mice. a tota ... | 2006 | 16871912 |
| deletion of znua virulence factor attenuates brucella abortus and confers protection against wild-type challenge. | znua is known to be an important factor for survival and normal growth under low zn(2+) concentrations for escherichia coli, haemophilus spp., neisseria gonorrhoeae, and pasteurella multocida. we hypothesized that the znua gene present in brucella melitensis 16 m would be similar to znua in b. abortus and questioned whether it may also be an important factor for growth and virulence of brucella abortus. using the b. melitensis 16 m genome sequence, primers were designed to construct a b. abortus ... | 2006 | 16790759 |
| successful treatment of pasteurella multocida meningitis with aztreonam. | this is the first reported case of the successful treatment of pasteurella multocida meningitis with aztreonam in a patient with multiple antibiotic allergies. | 2006 | 16798707 |
| antimicrobial activity and spectrum of cefovecin, a new extended- spectrum cephalosporin, against pathogens collected from dogs and cats in europe and north america. | cefovecin is a new extended-spectrum semisynthetic cephalosporin indicated for the treatment of bacterial infections in dogs and cats. this study evaluated the in vitro activity and spectrum of cefovecin against 2,641 recent clinical isolates (1,660 canine and 981 feline isolates) from europe and the united states. mic determinations against cefovecin and other reference antimicrobials were performed by broth microdilution methods recommended by the clinical and laboratory standards institute (c ... | 2006 | 16801403 |
| phylogenetic analysis of isolates of pasteurella pneumotropica from laboratory animals based on the gyrb gene sequence. | phylogenetic analysis using the gyrb sequence was performed to investigate the genetic relevance among 49 isolates of p. pneumotropica. in the phylogeny, the isolates were clearly classified into three groups as follows: group a for the isolates of biotype jawetz derived from mice, group b for the isolates of biotype jawetz derived from rats, and group c for the isolates of biotype heyl. these results suggest that the gyrb sequence of p. pneumotropica differs between the isolates of two biotypes ... | 2006 | 17090967 |
| detection of tetracycline-resistant and susceptible pasteurellaceae in the nasopharynx of loose group-housed calves. | the aim of the present study was to determine which pasteurella and mannheimia species are present in the upper respiratory tract of healthy calves with no history of antimicrobial treatment prior to sampling. the presence of subpopulations of tetracycline-resistant pasteurellaceae was also investigated. nasal swabs from 61 loose group-housed, clinically healthy calves, 1 to 4 months old, from 16 dairy herds were inoculated aerobically on a selective medium (columbia agar with 5% ovine blood and ... | 2006 | 17004035 |
| etiological agents of dairy cows' mastitis in western part of poland. | the purpose of the study was to determine the etiological mastitis agents in cows from herds located in the western part of poland in years 2003-2005. bacteriological examinations of 18,713 samples taken from california mastitis test (cmt) positive quarters were performed according to standard methods. some gram-negative bacilli and gram-positive cocci were examined with the use of api tests (analytical profile index). it was found that 32.7% of samples that were cmt positive were culture negati ... | 2006 | 17020014 |
| evolution of competence and dna uptake specificity in the pasteurellaceae. | many bacteria can take up dna, but the evolutionary history and function of natural competence and transformation remain obscure. the sporadic distribution of competence suggests it is frequently lost and/or gained, but this has not been examined in an explicitly phylogenetic context. additional insight may come from the sequence specificity of uptake by species such as haemophilus influenzae, where a 9 bp uptake signal sequence (uss) repeat is both highly overrepresented in the genome and neede ... | 2006 | 17038178 |
| antimicrobial susceptibility patterns of respiratory tract pathogens from sheep and goats. | to determine the antimicrobial susceptibility of common respiratory tract pathogens from sheep and goats. | 2006 | 17042733 |
| neonatal septicemia due to pasteurella multocida: the first case report in thailand. | neonatal septicemia acquired by vertical transmission of pasteurella multocida is very rare. the authors report a case of pasteurella multocida septicemia in a 2-day-old male infant. his mother had a history of prolonged premature rupture of membranes and subsequently developed fever. the patient had fever and lethargy at 36 hours of age, then developed severe pneumonia, sepsis, persistent pulmonary hypertension, renal failure and liver failure. although the appropriate antibiotics were given, h ... | 2006 | 17048443 |
| intrapleural heparin or heparin combined with human recombinant dnase is not effective in the treatment of empyema in a rabbit model. | the aim of this study was to investigate the effectiveness of intrapleural heparin or heparin combined with human recombinant dnase in the treatment of empyema. | 2006 | 17052304 |
| an unusual cause of sepsis and meningitis in a neonate. | 2006 | 17055368 | |
| pasteurella multocida septicemia in a newborn without scratches, licks or bites. | 2006 | 17058424 | |
| pharmacokinetics of cefovecin in cats. | the pharmacokinetics of the novel cephalosporin cefovecin were investigated in a series of in vivo, ex vivo and in vitro studies following administration to adult cats at 8 mg/kg bodyweight. bioavailability and pharmacokinetic parameters were determined in a cross-over study after intravenous (i.v.) and subcutaneous (s.c.) injections. [14c]cefovecin was used to evaluate excretion for 21 days after s.c. administration. protein binding was determined in vitro in feline plasma and ex vivo in transu ... | 2006 | 17083455 |
| pulmonary disposition of tilmicosin in foals and in vitro activity against rhodococcus equi and other common equine bacterial pathogens. | the objectives of this study were to determine the serum and pulmonary disposition of tilmicosin in foals and to investigate the in vitro activity of the drug against rhodococcus equi and other common bacterial pathogens of horses. a single dose of a new fatty acid salt formulation of tilmicosin (10 mg/kg of body weight) was administered to seven healthy 5- to 8-week-old foals by the intramuscular route. concentrations of tilmicosin were measured in serum, lung tissue, pulmonary epithelial linin ... | 2006 | 17083461 |
| endotoxin and mammalian host responses during experimental disease. | endotoxin is an integral component of the outer membrane of gram-negative bacteria and a prime example of unique and highly conserved bacterial surface molecules that engage with the innate immune system of the mammalian host via pattern recognition receptors on a range of host cells. the results of this interaction, which may be beneficial or detrimental to the development and welfare of the host, are reviewed, focusing on the different sensitivities and consequences in a range of hosts of expe ... | 2006 | 17101336 |
| immunization with outer membrane proteins of pasteurella multocida (6:b) provides protection in mice. | the immunoprotective efficacy of pasteurella multocida (6:b) outer membrane proteins (omps) was examined in the mouse model. bacterial omps were extracted using sarkosyl method and analysed by sodium dodecyl sulphate-polyacrylamide gel electrophoresis and immunoblotting. prototype vaccines were prepared using omps with adjuvants including dioleoyl phosphatidyl choline-based liposome and montanide isa206 water-in oil-in water emulsion. antibody response to the vaccine was monitored using indirect ... | 2006 | 17105574 |
| pasteurella multocida pathogenesis: 125 years after pasteur. | pasteurella multocida was first shown to be the causative agent of fowl cholera by louis pasteur in 1881. since then, this gram-negative bacterium has been identified as the causative agent of many other economically important diseases in a wide range of hosts. the mechanisms by which these bacteria can invade the mucosa, evade innate immunity and cause systemic disease are slowly being elucidated. key virulence factors identified to date include capsule and lipopolysaccharide. the capsule is cl ... | 2006 | 17107417 |
| [identification, biotypification and characterization of pasteurella multocida strains isolated in argentina]. | thirty pasteurella multocida strains isolated in argentina from human and animal samples were identified, biotypified and characterized. twenty-two (73%) strains were identified as p. multocida subsp. multocida, 5 (17%) as p. multocida subsp. gallicida, and 3 (10%) as p. multocida subsp. septica. all strains were grouped in 8 biotypes, and 70% of the strains presented capsular type a. the most frequent somatic serotypes were 1 (n:11) and 3 (n:9). p. multocida strains from swine source were resis ... | 2006 | 17152652 |
| [cat scratch pneumonia: a case report]. | pasteurella multocida infections can be caused by scratches or bites of many animals including pets. an unrecognized infection can lead to severe complications such as arthritis, osteomyelitis, respiratory infections and even meningitis or endocarditis. we present the case of a woman affected by soft tissue infection caused by pasteurella multocida complicated by bacteremia and pneumonia. | 2006 | 17228851 |
| one-pot three-enzyme chemoenzymatic approach to the synthesis of sialosides containing natural and non-natural functionalities. | chemoenzymatic synthesis, which combines the flexibility of chemical synthesis and the high selectivity of enzymatic synthesis, is a powerful approach to obtain complex carbohydrates. it is a preferred method for synthesizing sialic acid-containing structures, including those with diverse naturally occurring and non-natural sialic acid forms, different sialyl linkages and different glycans that link to the sialic acid. starting from n-acetylmannosamine, mannose or their chemically or enzymatical ... | 2006 | 17406495 |
| seppic vaccine adjuvants for poultry. | two inactivated antigens (newcastle and pasteurella multocida) were formulated with different adjuvants and tested in two separate experiments in poultry. oil formulations constituting water in oil (w/o) or water in oil in water (w/o/w) emulsions were assessed for antibody response, protection, local reactions, and vaccine physicochemical parameters. robust, efficacious, and safe formulations were obtained with w/o formulations whereas w/o/w was especially safe with maintained efficacy. results ... | 2006 | 17135512 |
| rep-pcr analysis of pasteurella multocida isolates from wild and domestic animals in india. | repetitive extragenic palindromic sequence-based pcr (rep-pcr) was used to characterize 67 field isolates of pasteurella multocida originating from different animal species and geographical regions of india. rep-pcr was found to be rapid and reproducible (three repeats were done). these isolates yielded different 23 profiles which were clustered into eight groups. the discrimination index was moderate (d value 0.83). somatic and antigenic typing of the isolates did not reveal any correlation wit ... | 2006 | 17139535 |
| [pasteurella multocida as a rare cause of neonatal meningitis]. | pasteurella multocida (p. multocida), a gram-negative bacillus is a typical commensal in the oropharynx of animals such as dogs and cats. human diseases caused by p. multocida are rare and include respiratory infections, sepsis and meningitis. p. multocida infections are described predominantly in patients with underlying chronic disorders, in elderly patients or in infants < or = 1 year. we describe the case of a 3-week-old boy with meningitis due to pasteurella multocida. p. multocida was also ... | 2006 | 17206557 |
| cloning and characterisation of the ahpa gene of pasteurella multocida serogroup b:2 (strain p52): short communication. | pasteurella multocida b:2 is responsible for haemorrhagic septicaemia in cattle and buffaloes, causing severe economic losses in the developing countries. in the present study, the ahpa gene of p. multocida b:2 (p52) was cloned, sequenced and compared with the previously reported ahpa gene sequence in p. multocida a:1, which is responsible for its haemolytic phenotype. e. coli dh5a cells were further transformed with recombinant plasmid carrying the ahpa gene from p. multocida b:2 (p52) but sds- ... | 2006 | 17278717 |
| quantification of mannheimia haemolytica leukotoxin by indirect elisa. | an indirect enzyme-linked immunosorbent assay (elisa) was developed for the quantification of extracellular leukotoxin (lkt) produced in chemostat culture of mannheimia haemolytica in a serum-free culture medium. leukotoxin purified with preparative sds-page was used for the production of chicken polyclonal antibodies (pab) that served as the primary detecting antibody. excising the lkt protein from an analytical sds-page gel proved an efficient technique for the purification of the toxin. conse ... | 2006 | 17283723 |
| evaluation of subgingival bacteria in the dog and susceptibility to commonly used antibiotics. | the aim of the present investigation was to evaluate the subgingival aerobic and anaerobic flora of 13 dogs with periodontal disease and the susceptibility of these bacteria to antibiotics currently approved in italy for treatment of canine infections. of the anaerobic bacteria, bacteroides fragilis was most frequently isolated, followed by peptostreptococcus + porphyromonas gingivalis and prevotella intermedia. of the aerobic bacteria, alpha-hemolytic streptococcus was most frequently isolated, ... | 2006 | 17286127 |
| [influence of cultivation time and composition of growth medium on formation of capsule, quantity and immunological properties of pasteurella multocida capsular antigen]. | results of study of capsule formation and immunologic properties of capsular antigen of attenuated strain la-25 of pasteurella multocida grown on liquid medium from non-food materials and hottinger's broth depending on cultivation time are presented. | 2006 | 17297891 |
| protective effect following intranasal exposure of goats to live pasteurella multocida b:2. | this study aimed to determine the effect of intranasal exposure to low doses of pasteurella multocida b:2 on survival of goats challenged with high doses of the same organism. eighteen goats were selected and divided into three groups. goats of group 1 were exposed intranasally twice, with a two-week interval, to 7 x 10(6) cfu/ml of live p. multocida b:2. goats of group 2 were not exposed to p. multocida b:2 but were kept together with the exposed group 1. goats of group 3 remained as unexposed ... | 2006 | 17265769 |
| [evaluation of two techniques of molecular subtyping to study pasteurella multocida]. | typeability, reproducibility, and discriminatory power of eric-pcr and apal-pfge to establish the genetic relation of p. multocida strains were determined. forty-nine strains of different source, biotype, capsular group, somatic serotype, and resistance to antimicrobials were studied. by eric-pcr, 31 patterns were defined with 10 to 14 bands in a rank of 0.2 and 1.2 kb. by apal-pfge, 37 restriction patterns were established with 7 to 15 bands of 34 to 450 kb. typeability was 100% (t=1) for eric- ... | 2006 | 17373089 |
| [presence of the microbiological risk in umbrian sawmills]. | the purpose of this study was to quantify and identify the airborne microbial contamination in umbria sawmills. in this paper we reported the preliminary results of our analysis. microbial contaminants (fungi and bacteria) were assessed with passive (ima standard) and active (sas microbial sampler) methods. there were significant differences of bacterial and/or fungal cfu/m3 values between the outdoor and indoor environments during the normal sawmills activity. staphylococcus, sphingomonas, past ... | 2006 | 17380948 |
| pasteurella multocida and its role in porcine pneumonia. | pasteurella multocida has been recognized as a contributor to debilitating and fatal porcine pneumonia for at least 120 years and there continues to be sustained, unabated high prevalence of the organism in cases submitted for diagnostic work up. understanding of its role in disease has been limited, in part because of difficulty in reproducing the disease experimentally with capsular type a strains of p. multocida, the predominant type associated with porcine pneumonia. this limitation has stym ... | 2006 | 17389051 |
| [pasteurella dagmatis: an unusual cause of vertebral osteomyelitis]. | vertebral osteomyelitis is a quite rare but severe cause of back pain in adults. various causative organisms have been reported. pasteurella species have rarely been isolated. we report here a case of vertebral osteomyelitis and consecutive cauda equina syndrome due to pasteurella dagmatis in a 60-year-old diabetic man. | 2007 | 17391865 |
| reclassification of [pasteurella] trehalosi as bibersteinia trehalosi gen. nov., comb. nov. | [pasteurella] trehalosi is an important pathogen of sheep, being primarily associated with serious systemic infections in lambs but also having an association with pneumonia. the aim of the present investigation was to characterize a broad collection of strains tentatively identified as [p.] trehalosi in order to reclassify and rename this taxon to support improvements in our understanding of the pathogenesis and epidemiology of this important organism. the type strain for [p.] trehalosi, strain ... | 2007 | 17392184 |
| experimental transmission of pasteurella multocida 6:b in goats. | haemorrhagic septicaemia (hs) is an acute disease of cattle and buffaloes caused by pasteurella multocida 6:b. outbreaks of the disease have been closely associated with carrier animals that transmit the organism to susceptible animals during stressful condition. this study was conducted to determine whether goats exposed intranasally to p. multocida 6:b can transmit the organism to contact goats. thirty-six healthy local katjang goats were divided into four groups and goats of groups 1 and 3 we ... | 2007 | 17381677 |
| the cloning and sequencing of the udp-galactose 4-epimerase gene (gale) from avibacterium paragallinarum. | the putative uridine diphosphate (udp)-galactose 4-epimerase encoding gene, gale, was isolated from avibacterium paragallinarum with the use of degenerate primers, colony hybridization and inverse pcr. the data revealed an open reading frame of 1017 bp encoding a protein of 338 amino acids with a molecular weight of 37 kda and an isoelectric point of 5.5. high sequence homology was obtained with an 87, 91 and 89% sequence identity on protein level towards the gale genes from actinobacillus pleur ... | 2007 | 17541831 |
| efficacy of danofloxacin in the treatment of pneumonic pasteurellosis in specific pathogen-free lambs. | 2007 | 17545648 | |
| outer membrane permeability for nonpolar antimicrobial agents underlies extreme susceptibility of pasteurella multocida to the hydrophobic biocide triclosan. | pasteurella multocida exhibits nonspecific susceptibility to nonpolar antimicrobial agents such as triclosan, despite possessing an ultrastructurally typical gram-negative cell envelope. capsulated and noncapsulated cell surface variants were examined to investigate the role outer membrane permeability plays in triclosan susceptibility. test strains were unable to initiate growth in the presence of bile salts and were susceptible to triclosan with minimal inhibitory concentrations (mics) ranging ... | 2007 | 17560745 |
| effect of ivermectin on the cellular and humoral immune responses of rabbits. | the objective of this paper is to determine the effect of ivermectin administration on cell mediated (cmi) and humoral immunity (hi) of rabbits. cmi against dinitrochlorobenzene (dncb) and sheep red blood cells (srbc) in rabbits was determined by delayed-type hypersensitivity and macrophage engulfment assay (mea), respectively; whereas, hi to pasteurella multocida b2 vaccine and srbc was determined by indirect haemagglutination assay (iha) and jerne hemolytic plaque formation assay (jhpfa), resp ... | 2007 | 17379254 |
| efficacy of haemorrhagic septicaemia alum-precipitated vaccine. | 2007 | 17277309 | |
| [pneumonia with septicemia caused by pasteurella multocida in an immunocompetent patient]. | pneumonia with septicemia caused by pasteurella multocida was diagnosed in an immunocompetent patient exposed to a dog. this case is remarkable by two aspects: first the absence of visible cutaneous lesion, and second the localization and severity of the infection caused by p. multocida even though the patient was immunocompetent. p. multocida can cause respiratory and systemic infection, and it is a possible diagnosis in case of exposure to animals, even without history of bite or scratch. furt ... | 2007 | 17303362 |
| communicable disease and health protection quarterly review: july to september 2006. from the health protection agency. | 2007 | 17311831 | |
| pasteurella multocida sepsis, due to a scratch from a pet cat, in a post-chemotherapy neutropenic patient with non-hodgkin lymphoma. | pasteurella (p) multocida exists in a variety of animals and causes diverse infections in humans due to animal bites and scratches, usually by cats or dogs, and oral and respiratory infection. we report a case of p multocida sepsis due to a scratch from a pet cat, complicated with disseminated intravascular coagulation in a post-chemotherapy neutropenic patient with non-hodgkin lymphoma. the patient was a febrile 79-year-old woman with disturbed consciousness and subcutaneous abscess in her righ ... | 2007 | 17321993 |
| differentiation of avian pasteurella multocida strains by single-primer pcr. | 2007 | 17294263 | |
| isolated endocarditis of the pulmonary valve caused by pasteurella multocida. | we describe the rare case of a patient with an isolated endocarditis of the pulmonary valve caused by pasteurella multocida. the bacterium was cultured from blood as well as from the excised valve after pulmonary valve replacement. risk factors were contact with animals and concurrent intravenous drug use. | 2007 | 17297591 |
| cloning and characterization of type 4 fimbrial gene (ptfa) of pasteurella multocida serogroup b:2 (strain p52). | 2007 | 17216317 | |
| cpg oligodeoxynucleotides augment the immune responses of piglets to swine pasteurella multocida living vaccine in vivo. | oligodeoxynucleotides containing unmethylated cpg motifs (cpg odn) prevent development of t-helper type 2 (th2) immune response and reverse established allergic responses in mouse models. however, little work on immune responses in piglets has been conducted in vivo. in this report, the ability of a porcine-specific cpg odn to act as an immunostimulant and enhance immune responses of piglets to swine pasteurella multocida living vaccine (spml vaccine) was determined. the titre of igg and igg1/ig ... | 2007 | 17223146 |
| modulation of host cell gene expression through activation of stat transcription factors by pasteurella multocida toxin. | the pasteurella multocida toxin (pmt) is highly mitogenic and has potential carcinogenic properties. pmt causes porcine atrophic rhinitis that is characterized by bone resorption and loss of nasal turbinates, but experimental nasal infection also leads to excess proliferation of bladder epithelial cells. pmt acts intracellularly and activates phospholipase c-linked signals and mapk pathways via the heterotrimeric galpha(q) and galpha(12/13) proteins. we found that pmt induces activation of stat ... | 2007 | 17150962 |
| a specific polymerase chain reaction based on the gyrb gene sequence and subsequent restriction fragment length polymorphism analysis of pasteurella pneumotropica isolates from laboratory mice. | for a molecular identification and typing tool, we developed a specific polymerase chain reaction (pcr) based on the gyrb gene sequence and a subsequent restriction fragment length polymorphism (rflp) analysis using the products amplified from the specific pcr to facilitate discrimination of biotypes of pasteurella pneumotropica from laboratory mice. appropriate pcr products, a 1039-basepair fragment for biotype jawetz and a 1033-basepair fragment for biotype heyl, were amplified by use of the p ... | 2007 | 17343354 |
| pasteurella multocida detection by 5' taq nuclease assay: a new tool for use in diagnosing fowl cholera. | a 5' taq nuclease assay utilising minor groove binder technology and targeting the 16s rrna gene was designed to detect pasteurella multocida (the causative agent of fowl cholera) in swabs collected from poultry. the assay was first evaluated using pure cultures. the assay correctly identified four p. multocida taxonomic type strains, 18 p. multocida serovar reference strains and 40 australian field isolates (17 from poultry, 11 from pigs and 12 from cattle). representatives of nine other pasteu ... | 2007 | 17346833 |
| mannheimia (pasteurella) haemolytica leukotoxin utilizes cd18 as its receptor on bighorn sheep leukocytes. | pneumonia caused by mannheimia (pasteurella) haemolytica is a highly fatal disease of bighorn sheep (ovis canadensis). leukotoxin (lkt), secreted by m. haemolytica, is an important virulence factor of this organism, and is cytolytic to bighorn sheep leukocytes. previously, we have shown that cd18, the beta subunit of beta2 integrins, serves as the receptor for lkt on bovine leukocytes. furthermore, anti-cd18 antibodies inhibit lkt-induced cytotoxicity of bighorn sheep leukocytes. therefore, we h ... | 2007 | 17347395 |
| specific identification of gallibacterium by a pcr using primers targeting the 16s rrna and 23s rrna genes. | gallibacterium was recently established as a new genus including organisms previously reported as pasteurella anatis, [actinobacillus] salpingitidis and avian pasteurella haemolytica-like organisms. the aim of the present study was to develop a pcr method allowing unambiguous identification of gallibacterium. pcr primers positioned in the 16s rrna (1133fgal) and 23s rrna (114r) genes were defined and their specificity was subsequently tested on 122 strains. twenty-five of the strains represented ... | 2007 | 17350770 |
| crystal structures reveal a thiol protease-like catalytic triad in the c-terminal region of pasteurella multocida toxin. | pasteurella multocida toxin (pmt), one of the virulence factors produced by the bacteria, exerts its toxicity by up-regulating various signaling cascades downstream of the heterotrimeric gtpases gq and g12/13 in an unknown fashion. here, we present the crystal structure of the c-terminal region (residues 575-1,285) of pmt, which carries an intracellularly active moiety. the overall structure of c-terminal region of pmt displays a trojan horse-like shape, composed of three domains with a "feet"-, ... | 2007 | 17360394 |
| successful treatment of pasteurella multocida meningitis with aztreonam. | this is the first reported case of the successful treatment of pasteurella multocida meningitis with aztreonam in a patient with multiple antibiotic allergies. | 2007 | 17366017 |
| fatal pasteurella multocida septicemia and necrotizing fasciitis related with wound licked by a domestic dog. | a 68-y-old male had necrotizing fasciitis and bacteremia due to pasteurella multocida. saliva culture from his dog grew p. multocida and pseudomonas aeruginosa. the human and dog p. multocida strains were of the same antibiogram but not identical tested with ribotyping. the wound licked by his dog was the only risk factor. | 2007 | 17366037 |
| mannheimia haemolytica leukotoxin-induced cytolysis of ovine (ovis aries) leukocytes is mediated by cd18, the beta subunit of beta2-integrins. | mannheimia (pasteurella) haemolytica causes severe pneumonia in cattle, sheep and goats. leukotoxin (lkt) is the most important virulence determinant produced by this organism. previously, we identified cd18, the beta subunit of beta(2)-integrins, as the receptor for lkt on bovine leukocytes. since lkt is specific for leukocytes of cattle, sheep and goats, we hypothesized that lkt utilizes cd18 as its receptor on ovine leukocytes as well. therefore, the objective of this study was to transfect a ... | 2007 | 17368825 |
| mutations in 16s rrna and ribosomal protein s5 associated with high-level spectinomycin resistance in pasteurella multocida. | pasteurella multocida isolates with high-level spectinomycin resistance in which no adenyltransferase genes could be demonstrated exhibited a c1192g transversion in the 16s rrna of all six or five of the six rrna operons and/or two different types of 3-bp deletions in the rpse gene that codes for the ribosomal protein s5. | 2007 | 17371823 |
| [bacteriological and virological status in upper respiratory tract infections of cats (cat common cold complex)]. | between october 2002 and january 2005,460 bacteriological samples from cats with an acute upper respiratory tract infection were analysed in clinical field studies in two accredited laboratories in germany. oropharyngeal swabs were taken from these cats and sent to the laboratories for routine diagnostics. in the swab samples of 460 cats 382 bacteria strains were isolated. the following bacteria were isolated most frequently: pasteurella spp. (32.5 %), staphylococcus spp. (18.5 %), escherichia c ... | 2007 | 17416134 |
| please, do not forget pasteurella multocida. | 2007 | 17806067 | |
| [severe pasteurella multocida pneumonia by close contact with a pet in chronic respiratory failure]. | 2007 | 17682434 | |
| [knee prosthesis infection due to pasteurella multocida]. | 2007 | 17692220 | |
| decoration of pasteurella multocida lipopolysaccharide with phosphocholine is important for virulence. | phosphocholine (pcho) is an important substituent of surface structures expressed by a number of bacterial pathogens. its role in virulence has been investigated in several species, in which it has been shown to play a role in bacterial adhesion to mucosal surfaces, in resistance to antimicrobial peptides, or in sensitivity to complement-mediated killing. the lipopolysaccharide (lps) structure of pasteurella multocida strain pm70, whose genome sequence is known, has recently been determined and ... | 2007 | 17704225 |
| contamination of post-endoscopic sinus surgery sinus cavities with pasteurella multocida. | 2007 | 17711761 | |
| pasteurella multocida sepsis and meningitis in 2-month-old twin infants after household exposure to a slaughtered sheep. | this article outlines 2 cases of pasteurella multocida sepsis and meningitis in 2-month-old twins after their father was exposed to a sheep during a sacrifice celebration at home. these cases emphasize the necessity of respecting basic hygiene rules and the danger involved in animal sacrifice without suitable professional structure. | 2007 | 17712748 |
| comparison of the in vitro susceptibility of rodent isolates of pseudomonas aeruginosa and pasteurella pneumotropica to enrofloxacin. | the objectives of this study were to determine and compare the in vitro enrofloxacin susceptibility of 94 pseudomonas aeruginosa isolates obtained from enrofloxacin-treated and untreated mice and that of 40 pasteurella pneumotropica strains and also to assess the efficacy and effects of enrofloxacin treatment of laboratory mice. the minimum inhibitory concentrations (mics) of enrofloxacin against all the ps. aeruginosa isolates were in the range of 1 to 4 microg/ml, whereas those against all the ... | 2007 | 17823403 |
| a multidomain outer membrane protein from pasteurella multocida: modelling and simulation studies of pmompa. | pmompa is a two-domain outer membrane protein from pasteurella multocida. the n-terminal domain of pmompa is a homologue of the transmembrane beta-barrel domain of ompa from escherichia coli, whilst the c-terminal domain of pmompa is a homologue of the extra-membrane neisseria meningitidis rmpm c-terminal domain. this enables a model of a complete two domain pmompa to be constructed and its conformational dynamics explored via md simulations of the protein embedded within two different phospholi ... | 2007 | 17888868 |
| susceptibility of bacterial pathogens against lincomycin/spectinomycin (1/2), penicillin g/neomycin (1/1), and penicillin g/dihydrostreptomycin (1/1) as determined in the bft-germvet monitoring program 2004-2006. | a total of 368 bacterial pathogens, including 72 coagulase-positive and coagulase-variable staphylococci, 97 beta-haemolytic streptococci, 51 escherichia coli, 75 pasteurella multocida, 25 mannheimia haemolytica, 25 pseudomonas aeruginosa, and 23 arcanobacterium pyogenes, were investigated for their susceptibility to the three combinations of antimicrobial agents lincomycin/spectinomycin (1/2), penicillin g/neomycin (1/1), and penicillin g/dihydrostreptomycin (1/1) in comparison to their suscept ... | 2007 | 17939451 |
| antimicrobial susceptibility of pasteurella multocida and bordetella bronchiseptica from dogs and cats as determined in the bft-germvet monitoring program 2004-2006. | a total of 92 canine/feline pasteurella multocida strains form respiratory tract infections or infections of skin/ear/mouth as well as 42 canine/feline bordetella bronchiseptica strains from respiratory tract infections were investigated for their susceptibility to antimicrobial agents. while the p. multocida strains were susceptible to all antimicrobial agents tested - except sulfonamides -, a considerable number of the b. bronchiseptica strains was resistant or exhibited high mic values agains ... | 2007 | 17939457 |
| quantitative resistance level (mic) of bacterial pathogens (escherichia coli, pasteurella multocida, pseudomonas aeruginosa, salmonella sp., staphylococcus aureus) isolated from chickens and turkeys: national resistance monitoring by the bvl 2004/2005. | in the study 2004/2005, the current quantitative resistance level of escherichia coli, pasteurella multocida, pseudomonas aeruginosa, salmonella sp. and staphylococcus aureus from chickens and turkeys was determined for the first time within the framework of the national resistance monitoring of the federal office of consumer protection and food safety (bvl). the objective was to implement a valid database on the basis of which the development and spread of resistance can be evaluated and monito ... | 2007 | 17939460 |
| reversible myocardial depression associated with sepsis in a dog. | 2007 | 17939574 | |
| pasteurella multocida bacteremia in asymptomatic plateletpheresis donors: a tale of two cats. | bacterial contamination of platelet (plt) concentrates occurs in 1 in 1000 to 1 in 3000 components and has been a leading cause of transfusion-associated morbidity and mortality. two cases of pasteurella multocida bacteremia in asymptomatic plateletpheresis donors are reported. clinical outcomes were profoundly different, emphasizing the importance of robust methods to detect bacterial contamination. | 2007 | 17958526 |
| shuffling of pig interleukin-2 gene and its enhancing of immunity in mice to pasteurella multocida vaccine. | in order to explore the safe and effective adjuvant for promotion of immunity of animals against infection, the experiment was carried out to shuffle tibet pig il-2 cdna with other il-2 cdna from human, yak and mouse, and the effect of shuffled il-2 (il-2s) gene in vivo was investigated on immunity of mice to pasteurella multocida. the il-2s protein was found to remarkably promote the proliferation of pig lymphoblasts than the native pig il-2 protein. then the il-2s gene was cloned into vr1020 e ... | 2007 | 17959278 |
| calcineurin-independent inhibition of 3t3-l1 adipogenesis by pasteurella multocida toxin: suppression of notch1, stabilization of beta-catenin and pre-adipocyte factor 1. | pasteurella multocida toxin (pmt) is a potent mitogen and a specific activator of gq-dependent signalling pathways. pmt impairs osteoblast differentiation and causes bone loss and fat reduction in vivo. we examined the effect of pmt on cell signalling pathways involved in 3t3-l1 adipocyte differentiation. we demonstrate that pmt treatment before or together with differentiation induction factors inhibits adipogenesis and prevents upregulation of important adipocyte markers - peroxisome-prolifera ... | 2007 | 17581254 |