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interferon and cytotoxic factor (cytotoxin) released in the blood of mice infected with mycobacterium bovis bcg. i. enhanced production of interferon and appearance of cytotoxin stimulated by capsular polysaccharide of klebsiella pneumoniae or bacterial lipopolysaccharide.interferon production stimulated by the active substance (neutral fraction) of the capsular polysaccharide of klebsiella pneumoniae (neutral cps-k) in bcg-infected mice was compared with that by bacterial lipopolysaccharide (lps). prior infection with bcg increased the responsiveness of mice to the lethal effect of neutral cps-k as well as to that of lps. associated with this, bcg-infected mice showed a markedly enhanced ability to produce interferon after stimulation not only by lps but also by ...197941163
delayed-type hypersensitivity and acquired cellular resistance in mice immunized with killed listeria monocytogenes and adjuvants.delayed-type hypersensitivity (dh) and acquired cellular resistance (arc) to listeria monocytogenes in mice was studied following immunization with killed bacteria in combination with freund's complete adjuvant or the adjuvant dimethyldioctadecylammonium bromide (dda). intracutaneous or intraperitoneal injections of killed listeria mixed with freund's complete adjuvant did neither result in dh nor in acr. intracutaneous injections of killed listeria and dda resulted in an antigen-dose dependent ...1979112043
suppressive effect of bacterial endotoxin on the expression of cell-mediated anti-listeria immunity.intravenous injection of bacterial endotoxin into mice at any time during ongoing infection with listeria monocytogenes resulted in a markedly increased multiplication of this organism in the liver and spleen. experiments designed to investigate the basis of this infection-enhancing effect revealed that endotoxin was also capable of inhibiting the expression of adoptive t-cell-mediated anti-listeria immunity if given to normal recipient mice up to 48 h before they were infused with protective t- ...1979112056
partial characterization of anti-tumor effector macrophages in the peritoneal cavities of concomitantly immune mice and mice injected with macrophage-stimulating agents. 1979115998
protection of mice against babesia microti with cord factor, coam, zymosan, glucan, salmonella and listeria.cord factor (trehalose 6-6' dimycolate). coam (chlorite-oxidized oxyamylose), zymosan, glucan, salmonella enteritidis 11rx and listeria monocytogenes were found to protect mice against subsequent infection with babesia microti, an intra-erythrocytic protozoan parasite. this protection was not observed after injection of staphylococcus epidermidis, a viridans group streptococcus, thioglycollate, or colloidal carbon. all the agents which protect against b. microti have also been reported to induce ...1979121772
resistance of essential fatty acid-deficient rats to endotoxic shock.the role of lipids in the altered energy metabolism of shock remains to be delineated fully. during the course of our studies of endotoxic shock, the susceptibility of essential fatty acid (efa)-deficient rats to endotoxin was evaluated. intravenous administration of s. salmonella enteritidis endotoxin (1 mg/100 gm) in normal male long-evans rats (7--8 weeks old) produced severe shock with an 88% mortality. in marked contrast, injection of this dose of endotoxin in efa-deficient rats of the same ...1979394879
diagnosis of salmonella infections: specificity of indirect immunofluorescence for rapid identification of salmonella enteritidis and usefulness of enzyme-linked immunosorbent assay.an indirect immunofluorescence (ifl) method was used for diagnosis of infections caused by salmonella enteritdis during an epidemic. antiserum prepared against the synthetic disaccharide tyvelose 1 leads to alpha 3 d-mannose, representative of salmonella o antigen 9, covalently linked to bovine serum albumin, was used. of 43 decal samples examined, 28 were positive for s. enteritidis by culture. ifl was applied (1) directly on fecal smears, (2) on enrichment broth cultures after incubation for 1 ...1979396337
shigella dysenteriae 1-like cytotoxic enterotoxins produced by salmonella strains.a salmonella enteritidis strain produced a cytotoxin in addition to heat-labile (lt) and heat-stable (st) enterotoxins. two strains of serotypes salmonella kapemba and salmonella thompson were lt and st negative, but exhibited a cytotoxic effect. after sephadex g-100 fractionation of the crude s. enteritidis material, some high and low molecular fractions had both cytotonic and cytotoxic activities. of the two other salmonellae, only some high molecular fractions contained the cytotoxic substanc ...1979396765
cross-protection aginst salmonella enteritidis infection in mice. i. immunization trials.mice were immunized subcutaneously with live and killed vaccines, with and without complete adjuvant incorporating salmonella typhi-murium m206, salmonella gallinarum 9r, salmonella pullorum sp223 as well as homologous salmonella enteritidis se795. the animals were challenged 21 days post-vaccination with 100 ld50 of virulent s. enteritidis 5694 smr subcutaneously along with unvaccinated control mice. to assess the immunity against acute and chronic infections, the percentage of absolute survivo ...1979397731
cross-protection against salmonella enteritidis infection in mice.mice were immunized subcutaneously with live vaccines and live vaccines with complete adjuvant incorporating salmonella enteritidis se 795, salmonella typhi-murium m206, salmonella gallinarum 9r or salmonella pullorum sp223. they were challenged along with unvaccinated controls with 100 ld50 of virulent s. enteritidis 5694 smr subcutaneously on the 21st day post-vaccination. the humoral immune response was studied by assessing the sequential level of agglutinins, complete and incomplete somatic ...1979397732
cross-protection against salmonella enteritidis infection in mice. iii. delayed hypersensitivity reaction and clearance of the challenge organism.mice were immunized with live vaccines and with live vaccines with complete adjuvant incorporating salmonella enteritidis, salmonella typhi-murium, salmonella gallinarum or salmonella pullorum. on the 21st day after vacination, the hypersensitivity reactions elicited by the mice to extracts of the challenge organism (s. enteritidis 5694 smr) were assessed. the degree of delayed hypersensitivity reaction was compared with the level of protection induced by the vaccine. the role in protection of d ...1979397733
a supplemental test system to measure competitive exclusion of salmonellae by native microflora in the chicken gut.an improved individual challenge test system is described for evaluation of competititve exclusion of salmonellae in day-old chicks by native gut microflora. evaluation of salmonella protection is based on culture of cloacal and fecal samples by enrichment methods plus enumeration of salmonellae in fresh droppings collected from test groups. the use of a nalidixic-acid-resistant strain of salmonella allowed for ease of measurement. comparative data are included that were developed by parallel te ...1979397829
inhibition of the growth of lewis lung carcinoma in syngeneic mice by salmonella antigens.administration of a protein antigen preparation from salmonella enteritidis 11rx at the site of challenge with lewis lung carcinoma inhibited tumour development in mice previously immunised with live bacteria, but not control mice. the kinetics of tumour growth indicated that the inhibition of tumour development was due to a reduction of the initial tumour inoculum rather than the development of specific anti-tumour immunity.1979398698
the intestinal flora and infant botulism.the intestinal flora of experimental animals interferes with infection by species of salmonella and shigella. protection against infection with these organisms appears to be related to high concentrations of volatile acids, low ph, and low oxidation-reduction potential of the intestinal contents of animals with an intact flora. there are no data to show that the flora influences colonization of the intestine with clostridial species, but indirect evidence suggests that the intestinal flora may b ...1979399374
[infections by enteritis-salmonellae in newborn and premature infants]. 1979399405
carbohydrate metabolism in c3h/hej (nonresponder) mice during endotoxic shock.this study was undertaken to evaluate the hypoglycemic effects of endotoxin in c3h/hej (nonresponder) mice. endotoxin from salmonella enteritidis ser typhimurium strain sr-11 was used and the median lethal dosed (ld50) for random-outbred swiss-webster mice and c3h/hej mice were 450 microgram and 3,000 microgram, respectively. at intervals after intraperitoneal injection of endotoxin (1 ld50) animals were killed, and blood glucose, liver glucose, and liver glycogen levels were killed, and blood g ...1979400573
[salmonella-cholecystitis (author's transl)].gastroenteritis due to salmonella enteritis is an endemic disease in our region, extraintestinal manifestations however are rare. we report a 8 years old girl who presented after 4 days of an unspecific diarrheal disease with watery liquid stools, vomiting, abdominal cramps, fever above 39 grad c and symptoms and signs of an acute abdominal emergency. mid abdominal laparotomy disclosed a cholecystitis with reactive peritonitis. cultures of bile showed salmonella group b as the causative organism ...1979530733
genetics of natural resistance to salmonellae in mice.the genetics of natural resistance to salmonellae were studied in f1 hybrid and backcross mice. overall resistance to salmonella typhimurium c5 is complex, but one parameter, the early net growth rate of the organism in vivo, is controlled by a single autosomal gene or cluster of genes. 'slow' net growth rate is necessary but insufficient, for resistance to s. typhimurium c5. resistance requires the participation of other mechanisms, detectable by the end of the first week, which presumably invo ...1979381179
the removal of 14c labeled endotoxin by activated charcoal.endotoxin shock due to gram-negative enteric bacteria is of major medical concern with an estimated 100,000 fatalities in the united states per year. an effective therapy for endotoxin shock, particularly in combination with significant liver damage, has not been available to date. since activated charcoal is known as a universal sorbent, the use of activated charcoal in a hemoperfusion apparatus to remove endotoxin has interesting possibilities. current assays for endotoxin are inadequate. the ...1979381215
transmissible antibiotic resistance in salmonella isolated from random-source cats purchased for use in research.salmonella isolates from random-source cats designated for use in research were examined for antibiotic susceptibilities and the presence of plasmids containing r factors. the serotypes studied were salmonella derby, s typhimurium, s anatum, s enteritidis, and s bredeney. eighty percent of the isolates were resistant to one or more antibiotics. the greatest frequency of resistance was to streptomycin. the majority of the salmonella isolates transferred all or a part of their antibiotic resistanc ...1979382928
fever and survival in the rat. the effect of enhancing fever.to study the effect of fever on infectious disease in a mammal, rats, partially restrained by an antirotatory device and with chronically implanted preoptic thermodes, were injected with salmonella enteritidis and, in some of them, the hypothalamus was then continuously cooled to enhance the febrile response. all animals developed a fever that peaked 2 days after the infection, reaching 40.9 +/- 0.2 (sd) degrees c in the nine hypothalamic cooled and only 39.8 +/- 0.4 degrees c in the 13 control ...1979384358
[comparison of the methods of detection of different types of salmonella in dairy products]. 1979384497
evaluation of several methods of detecting salmonellae in groups of chickens.chickens exposed experimentally to salmonella agona, s. blockley, s. enteritidis, s. infantis, and s. typhimurium were tested serologically by microagglutination and microantiglobulin procedures and culturally by cloacal swabs and environmental samples. chicks infected at one day old yielded the highest level of positive cloacal swab cultures, whereas exposure of older birds gave maximal serologic titers. recovery of salmonella from environmental samples is dependent on a number of factors, incl ...1979384988
reiter's syndrome after salmonella infection: occurrence in hla--b27 positive brothers. 1979385003
[urinary infection caused by salmonella enteritidis in schistosoma haematobium bilharziasis]. 1979386258
[effectiveness of oral immunization of white mice with a complex s. typhimurium antigen].the protective properties of hydroxylamine preparation obtained from a virulent strain of s. typhimurium were studied in experiments with natural infection after a single oral immunization. the new data obtained in these experiments suggest that the treatment of bacteria with hydroxylamine allows to produce the preparation which, when administered orally, has the immunizing dose only 20 times as great as its immunizing dose for subcutaneous administration. the action of gastric juice on hydroxyl ...1979386669
[salmonelloses in africa. bacteriological and epidemiological findings]. 1979387361
[meningitis caused by salmonellas]. 1979387362
endophthalmitis due to salmonella enteritidis. 1979387934
effect of capsular polysaccharide of klebsiella pneumoniae on host resistance to bacterial infections. iii. further study of its effects on interactions between peritoneal leukocytes and virulent salmonella enteritidis.the mechanism for the infection-promoting effect of the capsular polysaccharide of klebsiella pneumoniae (cps-k) was investigated using the experimental system in which mice were infected intraperitoneally (i.p.) with a virulent strain of salmonella enteritidis immediately after i.p. injection of cps-k. in the peritoneal phagocytes of cps-k-untreated control mice, approximately 70, 3, and 10% of phagocytized bacteria survived 6, 12, and 24 hr after challenge, respectively, when calculated from t ...1979388155
interferon and cytotoxic factor (cytotoxin) released in the blood of mice infected with mycobacterium bovis bcg. ii. influence of time after bcg inoculation on production of interferon and cytotoxin by capsular polysaccharide of klebsiella pneumoniae or by bacterial lipopolysaccharide and on hyperreactivity to their lethal effects.the time course of the occurrence of hyperreactivity in interferon and cytotoxin responses to the active substance (neutral fraction) of the capsular polysaccharide of klebsiella pneumoniae (neutral cps-k) and bacterial lipopolysaccharide (lps) and of the hyperreactivity to their lethal effects was followed after infection with bcg in sma and icr strains of mice. the duration of these hyperreactivities of bcg-infected mice depended on the inoculum doses of bcg. the time patterns of the hyperreac ...1979388156
[clinico-epidemiological analysis of an outbreak of salmonella bredeney infection in newborn infants]. 1979388542
endocarditis caused by salmonella enteritidis.a case of endocarditis caused by salmonella enteritidis is reported in a 20-year-old african woman. this is only the fourth published case. the development of this rare infection in the patient reported here probably resulted from a reduction in immunity caused by pregnancy and a past splenectomy.1979389258
isolation of pathogens other than yersinia pestis during plague investigations.from 1975 to 1978, 37 isolates of pasteurella multocida, 1 of salmonella enteriditis, and 5 of francisella tularensis were recovered from 42 mammalian specimens and 1 flea pool submitted for examination for evidence of infection with yersinia pestis. most of the specimens were collected during investigations of either a human plague infection or a reported epizootic among rodent populations. all specimens were of species regularly or occasionally involved in plague or tularemia cycles in nature ...1979392123
a biological study on hot-water extract from delipidated mycobacterium bovis strain bcg.the biological activity of a hot-water extract from delipidated bcg, designated as hsa (hot-water soluble adjuvant), was investigated. the hsa did not induce hyperreactivity to bacterial endotoxin. the hot-water extract from which nucleic acids had been removed by streptomycin (sm-hsa) was found to enhance the delayed-type hypersensitivity as evidenced by the results of footpad reaction of mice. the hsa and sm-hsa could be injected to mice by an intraperitoneal route for 20 consecutive days with ...1979392813
[interaction between salmonella and schistosomes. scanning electron microscopy study].in our attempts to elucidate the pathogenesis of prolonged salmonella bacteremia in patients with schistosoma mansoni or schistosoma haematobium infection, we have utilised meb. our results are significant. they show an association exists between bilharziasis and salmonellosis.1979393422
subtraction serum bactericidal assay: a method for estimating in vivo effects of antibiotic combinations.the subtraction serum bactericidal assay has been developed to assess the effects of the individual components of antibiotic combinations in serum specimens from patients with serious bacterial infection. the technique can be performed easily with conventional microtiter technology, and the results compare favorably with those obtained by conventional in vitro determinations of the additive and synergistic activity of fixed antibiotic combinations against various enterobacteriaceae. three combin ...1979393780
the child who is a salmonella carrier. to treat or not to treat? 1979371891
contraceptive properties of endotoxin in rabbits.endotoxin derived from salmonella enteritidis-boivin at a dose of 20 micrograms/kg intravenously interfered with follicular rupture normally induced by human chorionic gonadotropin (hcg) in rabbits. this action was greatest when the endotoxin was given 5 to 6 hours after the administration of hcg. the failure of follicular rupture resulted in entrapment of ova. endotoxin (5 micrograms/kg) given intravenously to rabbits on day 4 of pregnancy resulted in failure of implantation. indomethacin (2 mi ...1979371991
abdominal aortic salmonellosis.a recent example of salmonella mycotic abdominal aortic aneurysm is presented together with a review of the 24 other cases in the literature. emphasis is placed on common modes of presentation, diagnosis, and surgical management. a review of current theories of etiology is presented along with a new, more descriptive classification of mycotic aneurysms.1979373152
mucosal defenses against salmonella infection in the mouse.specific pathogen-free icr (institute of cancer research) mice were challenged with salmonella orally, aerogenically, or parentally 24 hr after they received sublethal whole-body irradiation. the early growth for the sublethal inoculum was identical in irradiated and control mice. in the irradiated group, salmonella multiplied in the liver and spleen until death of the host. increasing the dose of irradiation reduced the size of the mean lethal dose for the intravenous, intraperitoneal, and aero ...1979374651
protective effect of oral salmonella enteritidis 11rx infection against colon tumor induction by 1,2-dimethylhydrazine in mice.infection of mice with salmonella enteritidis 11rx has been shown previously to cause nonspecific immune stimulation and, consequently, resistance to subsequent challenge with a variety of transplantable tumors. the present study has examined the effect of infection with this organism in a chemical carcinogenesis system. colonic tumors were induced in laca and balb/c x c57bl/6jf1 mice by weekly s.c. injection of 1,2-dimethylhydrazine (15 mg/kg) for 28 weeks. infection of mice p.o. with live s. e ...1979376122
the incidence of salmonella in random-source cats purchased for use in research.in research facilities, cats are routinely ignored as a potential source of salmonella infection. over a period of 18 months, 142 cats received from commercial vendors for use in research were screened for enteric salmonella. salmonella was isolated from 15 animals, an incidence of 10.6%. five (29%) of the 17 shipments contained animals that were positive for salmonella. the serotypes isolated were salmonella derby, salmonella typhimurium, salmonella anatum, salmonella enteritidis, and salmonell ...1979376759
[purification and physico-chemical analysis of the fimbrial antigen in two different genera of enterobacteriacea: salmonella enteritidis and yersinia enterocolitica (author's transl)].chemical, physical and immunological properties of the fimbrial antigen of two different genera of enterobacteriaceae, namely salmonella (s. enteritidis) and yersinia (y. enterocolitica) were analysed. only a few strains of these two bacterial genera possess a fimbrial antigen which proved to be identical in all tests. purified fimbriae are unstable in buffer solutions. they tend to form aggregates, patterns of which are between 240000 and 270000. submitted to solubility testing by various metho ...1979377854
late deoxyribonuclease activity of salmonell enteritidis.as a result of chance observations, the authors studied for deoxyribonuclease activity 16 strains of salmonella, including six fresh isolates and ten stock cultures, with positive results in 13. reactions characteristically occurred at 48 hours or later, with the majority being manifest at 72 hours and the latest at six days. no other positive reaction was observed among approximately 7,000 enterobacteriaceae tested, except for serratia species and proteus vulgaris. deoxyribonuclease screening p ...1979377948
increased insulin responsiveness in endotoxicosis.the relation of endotoxicosis to insulin responsiveness was evaluated in male holtzman rats. salmonella enteritidis lipopolysaccharide at 0.5 or 1.0 mg per 300 g rat increased lethality in convulsive seizure deaths to 0.25, 0.50, or 1.0 u insulin sc. the hypoglycemic nadir induced by 0.05, 0.10, or 0.25 u of insulin sc was greater in rats rendered endotoxic with 1 mg of lipopolysaccharide iv. oxidation of u-14c-d-glucose to 14 co2 by endotoxic tissues in vitro was augmented in liver slices, epid ...1979378453
[institutional epidemic gastroenteritis caused by salmonella enteritis worthington type in 1976].an outbreak of gastroenteritis that occurred in a boarding school in mexico is described. the attack rate was 100% since all of 151 pupils were involved. salmonella enteritidis serotype worthington was identified as the only etiologic agent. this microorganism was isolated from 60% of the samples studied. due to the delay in notification the food ingested during the outbreak could not be analyzed.1979363132
late deoxyribonuclease activity of salmonella enteriditis. 19806153503
o-antigenic specificity of the protective supernatant factor from salmonella typhimurium effective in s. typhimurium-infected mice.a supernatant factor (sf) prepared from cultures of salmonella typhimurium protected naturally susceptible inbred mice against challenge with s. typhimurium subcutaneously injected (s.c.i.), but not against salmonella enteritidis, suggesting tha the relevant specificity involved lipopolysaccharide. further experiments were performed with two transductant strains of s. typhimurium. strain sh6701 has o-antigen 4 from s. typhimurium and sh6703 had o-antigen 9 from s. enteritidis. immunization with ...19806164034
[interest of gamma-glutamyltransferase in "enterobacteriaceae" (author's transl)].gamma-glutamyltransferase (gammagt) could be detected in 86,6% of 3,027 strains of enterobacteriaceae, by the use of gamma-l-glutamin-p-nitranilide acid for substrate. the following species produced gamma gt: citrobacter freundii, levinea malonatica, l. amalonatica, klebsiella pneumoniae, k. oxytoca, k. ozaenae, enterobacter aerogenes, e. cloacae, e. agglomerans, e. gergoviae, k. ozaenae, enterobacter aerogenes, e. cloacae, e. agglomerans, e. gergoviae, hafnia alvei, erwinia carotovora, serratia ...19806104464
lung cyclic 3',5'-adenosine monophosphate and adenylate cyclase in endotoxic shock.cyclic 3',5'-adenosine monophosphate (cyclic amp) and adenylate cyclase activity were measured in lungs from guinea pigs in endotoxic shock induced by an intravenous injection of salmonella enteritidis endotoxin (10 mg/kg body weight). both cyclic amp content and adenylate cyclase activity were significantly elevated in lung tissue from the endotoxic guinea pigs. there was no apparent change in the affinity of adenylate cyclase for its substrate (atp); however, the maximum velocity of the enzyme ...19806265202
[salmonella infections in germ-free and bacteroides-carrying guinea pigs]. 19806449805
[basic studies on prevention of experimental salmonellosis (1). distribution of spa producing strains of s. enteritidis and correlation of protective immunity between spa and killed vaccine (author's transl)]. 19806768821
treatment failures secondary to in vivo development of drug resistance by microorganisms.in two patients development of resistance to antibiotics by initially sensitive infecting organisms was associated with relapse or persistence of active infection. the first patient developed staphylococcus epidermidis resistant to chloramphenicol during therapy with this agent for an infection that followed a cerebrospinal fluid shunt, and the second patient developed bacteremia due to ampicillin-resistant salmonella during therapy with ampicillin. treatment failure resulting from in vivo devel ...19806771864
hypoxic reduction of endotoxic fever in guinea pigs. 19806772617
why are the killed s. typhi vaccines ineffective.the mosaic of proteins synthesized by s. typhi, s. enteritidis and e. coli, induced in immunized rabbits corresponding antibodies that precipitated almost indiscriminately numerous heterologous antigens. antibodies induced against eventual specific antigens could not be identified unless the sera were absorbed with heterologous proteins. the comparative immunochemical analysis of the total and absorbed sera proved that the proteins from e. coli are mixed with proteins sharing salmonella specific ...19806775438
mechanism of cellular suppression induced by oral tilorone treatment of mice.specific-pathogen-free b6d2 f1 hybrid mice were treated orally with tilorone hydrochloride (100 mg/kg of body weight per day) and infected with sublethal doses of listeria monocytogenes, salmonella enteritidis, mycobacterium bovis (bcg pasteur), or m. tuberculosis erdman. daily tilorone treatment inhibited the cell-mediated response to all of the intracellular parasites, and most of the mice succumbed to the challenge. tilorone suppressed delayed hypersensitivity responses to the microbial sensi ...19806777302
b cell tolerance: b cells rendered tolerant are present in the immune system in a potentially responsive form.the mechanisms of b cell tolerance were studied in an attempt to learn whether b cells rendered tolerant are present in the immune system in a potentially responsive form. the author tested the in vitro anti-trinitrophenyl (tnp) antibody-forming cell (anti-tnp afc) response to tnp-immunogens and polyclonal b cell activators (pba) of spleen cells taken from mice injected with a tolerogen, tnp-carboxymethylcellulose (tnp-cmc). spleen cells from mice injected 5 days previously with 10 microgram of ...19806971390
effect of endotoxin treatment on prostaglandin metabolism by rabbit uterus and oviduct.metabolism of pge-2 and pgf-2 alpha by cytosolic fractions (100,000 g supernatant) of the uterus, oviduct and lung of rabbits treated with hcg and endotoxin (20 microgram/kg) was measured. endotoxin caused immediate decreases in metabolism of both pgs by uterus at 1 h, and these decreases became significant at 2 h for pge-2 and 6 h for pgf-2 alpha. the metabolism of both pgs remained depressed throughout the 24 h study. metabolism by oviduct tissue differed in that at 1 h metabolism of both pgs ...19806987394
salmonella meningitis in infancy. 19806987813
salmonella reactive arthritis in british columbia. 19806987990
[clinical bacteriological characteristics of salmonellosis]. 19806988641
endotoxin-enhanced secretion of macrophage insulin-like activity. 19806989995
salmonella meningoencephalomyelitis in a northern fur seal (callorhinus ursinus).salmonella enteritidis was isolated from the brain of a neonatal northern fur seal (callorhinus ursinus) with gross and microscopic lesions of meningoencephalomyelitis. microscopic lesions in the liver and lung suggested septicemia.19806990022
adjuvant action of capsular polysaccharide of klebsiella pneumoniae on antibody response. viii. its effect on the size and the number of cells of regional lymph node and other lymphoid organs.changes in the number of cells and the weight of various lymphoid organs of mice, such as the regional lymph node (right inguinal node), spleen, thymus, bone marrow, and peripheral blood, were followed after the subcutaneous injection of the capsular polysaccharide of klebsiella pneumoniae (cps-k). for comparison, the changes after injection of various polyclonal lymphocyte activators (pla) including various preparations of bacterial lipopolysaccharide (lps) were concurrently studied. the number ...19806991886
ruptured mycotic aneurysm of a coronary artery. a fatal complication of salmonella infection.a 53-year-old man with a kidney transplant was hospitalized because of back pain, fever, and an enlarging heart size. cultures of blood and stool yielded salmonella enteritidis (group d, serotype enteritidis). despite appropriate antibiotic therapy, the patient died of cardiac arrest on the seventh hospital day. autopsy revealed a ruptured mycotic aneurysm of the right coronary artery with hemopericardium. in addition, a ruptured aneurysm of the abdominal aorta was present. to our knowledge, rup ...19806994672
mechanism of hyperinsulinemia in endotoxicosis.hyperinsulinemia subsequent to endotoxemia is a key factor leading to the disturbance of glucose homeostasis in endotoxin shock. this study investigated the mechanism(s) of hyperinsulinemia during endotoxicosis in the rat. two primary mechanisms for the hyperinsulinemia were evaluted: 1) decreased removal of insulin by the endotoxic liver, and 2) increased secretion of insulin by the endotoxic pancreas. endotoxin treatment of donor rats did not impair the removal of tca-precipitable 125i-labeled ...19806996494
unusual aspects of salmonella meningitis.two cases of salmonella meningitis that demonstrate unusual clinical and epidemiologic features are reported. the first case was a two-month-old infant with relapsing salmonella meningitis in whom echo 2 virus and s. enteritidis grew in mixed culture from cerebrospinal fluid. the second case was a five-month-old with typhoid meningitis. although this patient eventually responded to chloramphenical, repeated csf cultures grew s. typhi despite his receiving high dose parenteral therapy with ampici ...19806996893
[enteritis salmonellae in man and animal from 1953 to 1975 in southern bavaria (author's transl)].the present paper gives a survey of the enteritis salmonelloses in man during the years from 1953 to 1975 (19400 first isolations) and in animals in the period from 1965 to 1975 (4600 first isolations and identification) in southern bavaria. in southern bavaria the number of isolations from enteritis salmonellae in man and animal has strongly increased during the last few years and the same holds good for the number of serotypes (figs. 1, 2 and tables 1, 2). the most frequent serotypes in man ar ...19806998205
experimental nephropathy induced in rabbits by immunization with escherichia coli 055 lipopolysaccharide. 2. immunologic findings.thirty-seven rabbits were immunized against lipopolysaccharide from escherichia coli or salmonella enteritidis over a period of up to 16 months. the animals developed antibodies against rabbit renal glycoproteins and against bacterial polysaccharide; they also showed signs of kidney lesions. the immunoperoxidase test showed antibody and complement (c3) fixation on the periphery of glomeruli and tubules. antibodies extracted from the kidneys of the immunized animals reacted with isologous and aut ...19806998923
vector potential of the german cockroach (dictyoptera: blattellidae) in dissemination of salmonella enteritidis serotype typhimurium. 19806999154
complement-independence of the acute-phase production of serum amyloijd p-component (sap) in mice.mice depleted of circulating c3 by injection of cobra factor (cof), the c3-activating protein of cobra (naja naja) venom, mounted the same acute-phase responses of serum amyloid p-component (sap) to subsequent injection of casein, bacterial lipopolysaccharide or croton oil as did normal control mice. there was also evidence for accelerated synthesis of c3 itself in response to injection of these acute-phase stimulants in cof-treated mice. on the other hand complement activation produced by injec ...19807000131
factors affecting the ability of various strains of enterobacteriaceae to induce tumour resistance in mice.primary infection of mice with salmonella enteritidis 11rx (11rx) confers resistance to challenge with 10(4) ld50 doses of ehrlich ascites tumour (eat). a lipopolysaccharide-free protein extract of 11rx is capable of eliciting delayed type hypersensitivity (dth) reactions in these mice and of "recalling" tumour resistance in long-term 11rx immunised mice, which no longer exhibit any resistance to tumour challenge. in the present study, we have examined the ability of five other strains of entero ...19807002136
cholera toxin-like toxin released by salmonella species in the presence of mitomycin c.several serotypes of salmonella were shown to release increased amounts of a cholera toxin-like toxin during culture in vitro with mitomycin c (mtc). filter-sterilized culture supernatants containing the toxin caused elongation of chinese hamster ovary cells, which could be blocked by heating the supernatants at 100 degrees c for 15 min or by adding mixed gangliosides or monospecific cholera antitoxin. when mtc was not added to the salmonella cultures, little or no toxin was detected in crude, u ...19807002788
mapping of genes determining penicillin-resistance and serum-sensitivity in salmonella enteritidis.two presumptive single-step mutants, resistant to penicillin and sensitive to the bactericidal effect of normal human serum, were isolated on penicillin gradient plates from a smooth, penicillin-sensitive, serum-resistant strain of salmonella enteritidis (o9,12; gal hisei cys). the chemical composition of their lipopolysaccharides, their phage-sensitivity patterns, and their serological and cultural properties showed one to be 'part-rough' and the other smooth. hfr strains with o antigens o4,5,1 ...19807003058
[salmonella enteritidis in gastroenteritis in a day-nursery. epidemiological observations in a primary food-borne infection]. 19807003878
[incidence and prevention of food-borne salmonella infections]. 19807003879
effects of endotoxin from different bacteria on ovum transport in rabbits. 19807004496
enhanced sensitivity to endotoxin induced by the re stimulant, glucan.pretreatment of rats with the res stimulant, glucan, markedly increases their sensitivity to endotoxic shock. intravenous administration of s. enteritidis endotoxin (10 micrograms/100 gm b.w.) produced a more severe shock in glucan-pretreated rats than iv injection of 1 mg/100 gm b.w. of endotoxin in normal rats. endotoxic shock in glucan-sensitized rats was associated with a precipitous increase in serum activity of lysosomal enzymes and a more severe hypoglycemic response. the shocked glucan-p ...19807004658
[collective food poisoning caused by salmonella enteritidis in the katowice province]. 19807017824
community-acquired purulent meningitis: a review of 1,316 cases during the antibiotic era, 1954-1976.this review of 1,316 cases of purulent meningitis assessed changes in the etiology, clinical features, and fatality rate during the antibiotic era. hemophilus influenzae was the most frequent cause of purulent meningitis (458 cases), neisseria meningitidis the second most frequent (396 cases), and streptococcus pneumoniae the third most frequent (178 cases). no bacterial etiology was found for 148 patients with purulent meningitis, the fourth major category of meningitis throughout the 23 years ...19806763303
[salmonella infection epidemic caused by milk product contamination with salmonella enteritidis in the wroclaw province in june 1978]. 19806893495
[current significance of juvenile salmonella infections]. 19807007796
[complement changes in pneumonia and bronchospastic reactions in infants]. 19807008013
elevated thromboxane levels in the rat during endotoxic shock: protective effects of imidazole, 13-azaprostanoic acid, or essential fatty acid deficiency.the potential deleterious role of the proaggregatory vasoconstrictor, thromboxane a(2), in endotoxic shock was investigated in rats. plasma thromboxane a(2) was determined by radioimmunoassay of its stable metabolite thromboxane b(2). after intravenous administration of salmonella enteritidis endotoxin (20 mg/kg), plasma thromboxane b(2) levels increased from nondetectable levels (<375 pg/ml) in normal control rats to 2,054+/-524 pg/ml (n = 8), within 30 min to 2,071+/-429 at 60 min, and decreas ...19807350199
an outbreak of salmonella enteritis and septicemia in a population of uremic patients. a review of four cases, including infection of an arteriovenous fistula.an outbreak of enteritis and septicemia caused by salmonella enteritidis occurred in a population of uremic patients treated in a nephrology unit. in one of the patients, an arteriovenous fistula was infected by this organism. the source of the outbreak was traced to the refrigerator and sink in the unit. this degree of morbidity and mortality far exceeds that previously reported in infections with nontyphoid salmonella sp and is presumbly related to the decreased immune response seen in uremia.19807387303
[reiter's disease following salmonella infection in an hl-a-b27 carrier].reiter's syndrome following salmonella enteritidis (gärtner) infection in an hla-b27 carrier is described. some weeks after an episode of fever and diarrhea, a 33-year-old male presented with sacroiliitis, achilles tendinitis and aphthous stomatitis. during the next few months he developed chronic arthritis, mild conjunctivitis, severe iritis, oligospermia and nonspecific asymptomatic urethritis.19807394503
[role of the classical and alternative complement pathways in chemotaxis of human c2 deficiency (author's transl)].the roles of the classical and alternative complement pathways in the formation of chemotactic factors were comparatively evaluated in a normal serum and a serum from a child with congenital c2 deficiency. neutrophil chemotactic index was determined by a direct microscopic observation using serum activated by an immune complex for the classical pathway, and by zymosan a or liposaccharide of salmonella enteritidis for the alternative pathway. chemotactic activity was observed only when the c2-def ...19807396417
salmonellosis and arizonosis in the reptile collection at the national zoological park.the prevalence of salmonella and arizona organisms in the reptile collection at the national zoological park was investigated. culture of specimens from 311 reptiles, while live or at necropsy, yielded yielded 117 positive results, for an overall infection rate of 37%. snakes had the highest rate, 55% (69 of 125); lizards had an intermediate rate, 36% (46 of 129); and turtles and tortoises had the lowest rate, 3% (2 of 63). twenty-four serotypes of salmonella enteritidis, 1 of s choleraesuis, an ...19807451315
[genetic variability of microorganisms, determined by r plasmids. iii. genetic properties of plasmid aggregates]. 19807010333
chloramphenicol resistant strains in salmonellosis in jakarta.during an observation period of 20 months (from january 1978 to september 1979) 123 children with clinically suspected salmonellosis were admitted to the department of pediatrics, 70 males and 53 females varying in age from 17 days to 14 years. s. typhi or s. enteriditis was isolated from the stool, urine, blood or cerebrospinal fluid in 85% (105/123) of the cases. the results of the microbiologic examination showed that 28 out of the 105 cases (27%) were resistant to chloramphenicol of which th ...19807013096
[effect of different diet composition on the immunologic reactivity of guinea pigs]. 19807013378
distribution of 203pb during lead-potentiated endotoxic shock. 19817016579
cross protection against fowl typhoid. immunisation trials and humoral immune response. 19817016618
fever and trace metal changes in endotoxin-challenged neonates.during infections, plasma fe and zn generally fall, while body temperature and plasma cu rise. however, infected neonates usually do not develop fever during the first week of postnatal life. while fever could not be evoked in neonatal guinea pigs by 2 micrograms/kg of s. enteritidis endotoxin until they were 8 days old, their plasma levels of fe and zn were lowered significantly from birth; plasma cu tended to increase from 2 days postnatally. these results indicate that, contrary to the refrac ...19817010303
protective effects of aspirin in endotoxic shock.endotoxic shock is associated with increased metabolism of arachidonic acid to thromboxanes (tx) and prostaglandins (pg). this study assessed the effects of varied doses of aspirin, an inhibitor of arachidonic acid metabolism, on salmonella enteriditis endotoxin (20 mg/kg)-induced mortality, plasma levels of arachidonate metabolites and other pathophysiological sequelae in long-evans rats. aspirin, in doses of 3.75, 15 an 30 mg/kg, given 30 min before endotoxin significantly (p less than .01) im ...19816894770
implications for thromboxane a2 in the pathogenesis of endotoxic shock.during endotoxemia there is increased synthesis of arachidonic-acid-derived metabolites. we investigated the potential deleterious role of the proaggregatory vasoconstrictor, thromboxane a2, an arachidonic acid metabolite, in the endotoxic shocked rat. plasma levels of thromboxane b2, the stable metabolite of thromboxane a2, 6-keto-pgf1 alpha, the stable metabolite of pgi2, and pge were measured via radioimmunoassay. we also investigated the therapeutic efficacy of the fatty acid cyclo-oxygenase ...19816961767
group d salmonella thoracic aortitis: a case report. 19817043768
salmonella enteritidis isolated from sputum: report of case. 19817019168
opsonization of salmonella enteritidis lipopolysaccharide in sickle cell disease. 19817019833
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