Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| cloning and sequence analysis of the major outer membrane protein gene of chlamydia psittaci 6bc. | the gene encoding the major outer membrane protein (momp) of the psittacine chlamydia psittaci strain 6bc was cloned and sequenced. n-terminal protein sequencing of the mature momp indicated that it is posttranslationally processed at a site identical to the site previously identified in the momp of chlamydia trachomatis l2. the nucleotide sequence of the c. psittaci 6bc momp gene was found to be 67 to 68% identical to those of human c. trachomatis strains, 73% identical to that of chlamydia pne ... | 1991 | 1856001 |
| genetic diversity and identification of human infection by amplification of the chlamydial 60-kilodalton cysteine-rich outer membrane protein gene. | the 60-kda cysteine-rich outer membrane protein genes of chlamydia psittaci, chlamydia pneumoniae, and chlamydia trachomatis have very different 5' ends, but two areas flanking this variable region show absolute sequence conservation. this observation permitted differentiation of the three species of chlamydia by the polymerase chain reaction (pcr), forming the basis of a diagnostic test for chlamydial infections. the pcr product containing the variable region of the respective 60-kda crp genes ... | 1991 | 1864938 |
| [anti-chlamydia psittaci antibodies in a healthy pediatric population]. | psittacosis or ornithosis is a bird disease caused by chlamydia psittaci which can be transmitted to man. little is known of the epidemiology of the disease in this region, but occasional cases which have been brought to the authors' attention have prompted an epidemiological study on the subject. the preliminary results indicate a surprising percentage, over 8%, of antibodies in infants and children. this percentage varies little in relation to place of residence, rural or urban, or the presenc ... | 1991 | 1870537 |
| evaluation of an immunofluorescence test on direct smears of conjunctival and urogenital swabs taken from koalas for the detection of chlamydia psittaci. | the chlamydia-cel vet if test (ccvit), a commercially available immunofluorescence test for use on direct smears of clinical specimens, was evaluated in a colony of 43 captive koalas. the test is based on a monoclonal antibody directed against the chlamydial common group specific lipopolysaccharide antigen. swabs were taken from conjuncitva and penis or urogenital sinus and used for direct smear evaluation and cell culture isolation. compared with isolation of the organism in cell culture, the c ... | 1991 | 1883293 |
| chlamydial infection in a colony of captive koalas. | forty three koalas in a captive colony were investigated for the presence of chlamydia psittaci infection and associated disease. swabs were taken from conjunctivae and urogenital sites for cell culture isolation of c psittaci and for cytological examination (direct smears) for chlamydial inclusions and evidence of inflammation. on the basis of cell culture isolation, 28 samples from 25 koalas were positive for c psittaci (that is, infected). three koalas were positive from both sites, 5 from co ... | 1991 | 1883294 |
| chlamydia pneumoniae elementary body antigenic reactivity with fluorescent antibody is destroyed by methanol. | methanol, used for fixing chlamydia organisms to microscopic slides, was shown to eliminate the antigenic reactivity of chlamydia pneumoniae elementary bodies with fluorescent antibodies. acetone fixation had no adverse effect. chlamydia trachomatis and chlamydia psittaci were not affected by methanol fixation. the effect of methanol on c. pneumoniae is another characteristic that differentiates this species from the other two chlamydia species. | 1991 | 1885752 |
| serotyping of chlamydia psittaci isolates using serovar-specific monoclonal antibodies with the microimmunofluorescence test. | a panel of 10 serovar-specific monoclonal antibodies that could distinguish 10 distinct serovars of chlamydia psittaci was prepared. the panel included one monoclonal antibody to each of the 10 serovars. monoclonal antibodies were selected for their specificity in the indirect microimmunofluorescence test. each of the monoclonal antibodies had a titer of 1:1,280 or higher to the homologous strain, with only two showing any cross-reactivity at a dilution of 1:10. chlamydial antigen derived from o ... | 1991 | 1890172 |
| [simultaneous infection by coxiella burnetii and chlamydia psittaci in 2 patients: the problem of psittacosis of non-avian origin]. | 1991 | 1895793 | |
| pcr test for chlamydia psittaci. | 1991 | 1897094 | |
| the use of fluorescein-conjugated monoclonal antibodies, cell culture and transmission electron microscopy to detect chlamydia psittaci and associated lesions in experimentally infected mice. | an immunofluorescence test based on a monoclonal antibody (mab) was used to demonstrate chlamydiae in formalin-fixed and paraffin wax-embedded tissues from 10 adult mice experimentally infected by the oral route with chlamydia psittaci isolated from the fetal membranes of an aborted ovine fetus. samples of lung, jejunum and spleen were examined by bright-field microscopy, immunofluorescence and transmission electron microscopy, and were cultured for chlamydia in mccoy cells. these tissues were c ... | 1991 | 1918451 |
| ovine psittacosis and sarcoidosis in a pregnant woman. | a woman in the first trimester of pregnancy presented with pneumonia and hilar lymphadenopathy after exposure to lambing ewes. she subsequently aborted. infection with chlamydia psittaci of ovine origin was confirmed. pregnant women are susceptible to this infection, which may cause life threatening disease. the patient also had features of sarcoidosis, and the two conditions ran a similar time course. there is a possibility that ovine psittacosis caused an illness indistinguishable from sarcoid ... | 1991 | 1926035 |
| gamma interferon-activated human macrophages and toxoplasma gondii, chlamydia psittaci, and leishmania donovani: antimicrobial role of limiting intracellular iron. | iron-saturated transferrin did not reverse the intracellular killing or inhibition of toxoplasma gondii, chlamydia psittaci, or leishmania donovani by gamma interferon-activated human macrophages. deferoxamine, an iron chelator, also did not impair replication within unstimulated macrophages. limiting the availability of intracellular iron is an unlikely mechanism in human macrophage activity against these three diverse pathogens. | 1991 | 1937829 |
| [meningism as the main symptom of chlamydia psittaci infection]. | 1991 | 1944716 | |
| [bacteriologic studies of the occurrence of chlamydia psittaci in organs of swine and in aborted swine fetuses]. | by inoculation of embryonating chicken eggs via the yolk sac route chlamydia psittaci was grown from 11 lungs of 45 pigs with pneumonia (24.4%). from the lungs of 55 pigs with other diseases the organism was isolated in five cases (9.1%). chlamydiae were not detectable by cultural methods in the uterine mucosa of 87 sows, arthritic joints of 30 store pigs and in aborted fetuses. a commercial available enzyme amplified immunoassay indicated the presence of chlamydial antigen in mucosal scrapings ... | 1991 | 1950250 |
| the antigenic specificity of the humoral immune response to primary and repeated ocular infections of the guinea pig with the gpic agent (chlamydia psittaci). | the antigenic specificity of the humoral immune response in guinea pigs to primary and repeated ocular infections with the guinea pig inclusion conjunctivitis (gpic) chlamydial agent was analysed using microbiological, serological and western blotting techniques. the results indicate that although there was a response to many minor polypeptide antigens, there was a marked lack of reactivity to the major outer membrane protein (momp), particularly following reinfection of guinea pigs. it is sugge ... | 1991 | 1955051 |
| atypical pneumonia. | the atypical pneumonia syndrome usually implies a benign illness where systemic complaints predominate over respiratory symptoms. cough is prominent; chest radiographic findings are varied. many organisms are associated with this syndrome. mycoplasma pneumoniae, chlamydia psittaci, chlamydia pneumoniae, coxiella burnetii, and francisella tularensis are reviewed in this article. | 1991 | 1955701 |
| ocular chlamydial zoonosis: an experimental study in monkeys. | two locally isolated strains of chlamydia psittaci from faeces of apparently healthy sheep and conjunctiva of holstein heifers suffering from conjunctivitis and pneumonia were used for ocular experimental studies in 7 rhesus monkeys. titrated (eld50 10(3.6)/0.2 ml and 10(4.5)/0.2 ml) partially purified yolk sac suspension of each strain was instilled onto conjunctiva of each animal. the clinical and laboratory studies were followed till 8 weeks post-infection. both the strains produced trachoma ... | 1991 | 1959319 |
| diagnosis of pneumonia by cultures, bacterial and viral antigen detection tests, and serology with special reference to antibodies against pneumococcal antigens. | in a prospective study of the etiology of pneumonia 196 adult patients were included. one of the following criteria was required for diagnosis of pneumococcal pneumonia: isolation of pneumococci from blood; isolation from transtracheal aspirate; isolation from sputum or nasopharynx or detection of capsular antigen in sputum in combination with a significant increase in antibodies against at least one pneumococcal antigen (type-specific capsular polysaccharide, c-polysaccharide, pneumolysin); or ... | 1991 | 2019757 |
| comparison of isolates of chlamydia psittaci of ovine, avian and feline origin by analysis of polypeptide profiles from purified elementary bodies. | the single species chlamydia psittaci is a diverse grouping which contains several different types of chlamydial strain for which there is no generally accepted typing method. the results obtained when profiles of polypeptides from purified elementary bodies are compared are consistent with type designations obtained using other criteria. however, the method still requires large scale culture and extensive purification of the chlamydial cells. | 1991 | 2024446 |
| detection of chlamydia psittaci from avian field samples using the pcr. | 1991 | 2028566 | |
| psittacosis and arthritis. | recent findings justify the opinion that chlamydia psittaci is the reappearance of a forgotten pathogen. the clinical manifestation and the course of psittacosis are extremely variable, whereas the clinical spectrum of the infection with the different strains of c. psittaci is not known. reactive arthritis during the course of psittacosis has been rarely described in humans. however, it has been stated that c. psittaci could be added to the list of infectious agents able to induce reactive arthr ... | 1991 | 2032470 |
| detection of chlamydia psittaci using dna probes and the polymerase chain reaction. | fewer than 10(5) elementary bodies of chlamydia psittaci could be detected by using dna hybridisation with a plasmid probe specific for avian chlamydial strains. pcr amplification of chlamydial dna using primers specific for conserved regions of the major outer membrane protein gene enabled the detection of fewer than 10 elementary bodies. dna could be amplified from 22 of the 24 chlamydial strains tested including avian, feline, ovine, caprine, koala and lymphogranuloma venereum strains. | 1991 | 2037227 |
| sequence analysis and lipid modification of the cysteine-rich envelope proteins of chlamydia psittaci 6bc. | the envelopes of elementary bodies of chlamydia spp. consist largely of disulfide-cross-linked major outer membrane protein (momp) and two cysteine-rich proteins (crps). the momp gene of chlamydia psittaci 6bc has been sequenced previously, and the genes encoding the small and large crps from this strain were cloned and sequenced in this study. the crp genes were found to be tandemly arranged on the chlamydial chromosome but could be independently expressed in escherichia coli. the deduced 87-am ... | 1991 | 2050637 |
| towards a differential polymerase chain reaction test for chlamydia psittaci. | 1991 | 2053263 | |
| hepatitis in a family infected by chlamydia psittaci. | hepatic involvement is considered a rare complication of psittacosis. occurrence of icteric hepatitis as the cardinal manifestation of the disease has been rarely reported. we describe two members of a family infected by psittacosis, in whom icteric hepatitis was the prominent expression of the disease. the diagnosis of psittacosis was confirmed by isolation of the pathogen and by detection of serum antibodies to chlamydia species. no serological evidence for acute twar infection was found. chla ... | 1991 | 2061902 |
| pneumonia. patient profiles, choice of empiric therapy, and the place of third-generation cephalosporins. | choosing appropriate antimicrobial therapy for patients with pneumonia requires knowledge of the etiologic agents seen in specific kinds of patients at specific times and places. for community-acquired pneumonia, there is an important difference in the agents seen in the normal and the compromised host. the normal host most often presents with viral, mycoplasmal, or pneumococcal pneumonia. the exact place of chlamydia pneumoniae is still under study. a normal host who aspirates is at risk of ana ... | 1992 | 1730186 |
| detection of igm antibodies to chlamydia trachomatis, chlamydia pneumoniae, and chlamydia psittaci from japanese infants and children with pneumonia. | chlamydia trachomatis (c. trachomatis) is now well established as a pathogen of neonatal inclusion conjunctivitis and infantile pneumonia. c. pneumoniae (twar) and c. psittaci also cause pneumonia and other respiratory infections. serum samples from 223 japanese infants and children with pneumonia were tested for igm antibodies to c. trachomatis, c. pneumoniae and c. psittaci. igm antibodies to c. trachomatis were measured by an enzyme immunoassay (eia) and by a microimmunofluorescence (mif) tes ... | 1992 | 1296808 |
| purification of chlamydia psittaci antigen by affinity chromatography on polymyxin b agarose for use in the enzyme-linked immunosorbent assay (elisa). | the purification of cell wall antigens of chlamydia psittaci by affinity chromatography on polymyxin b agarose is described. chlamydial cell wall antigens were prepared using different methods: heat treatment, ultrasonication and sodium deoxycholate treatment. the antigens were subsequently purified by gel chromatography. the highest amount of cell wall antigens was obtained by heat treatment of the chlamydiae at 90 degrees c and ph 8.5. the purified antigens showed molecular weights of 450 kda ... | 1992 | 1303687 |
| evaluation of the polymerase chain reaction (pcr) for detection of chlamydia psittaci in abortion material from ewes. | the polymerase chain reaction (pcr) was evaluated as a diagnostic tool for detection of chlamydia (c.) psittaci in abortion material from 40 ewes. for this purpose, pcr results of 87 samples were compared with direct microscopic identification after chemical staining, cell culture isolation and a commercially available enzyme-linked immunosorbent assay (elisa). the value for sensitivity as compared to cell culture was 97.7% whereas the specificity-value was calculated to be 84.1%. | 1992 | 1303688 |
| serological survey for bovine bacterial and viral pathogens in captive arabian oryx (oryx leucoryx pallas, 1776). | tests for antibodies to bovine bacterial and viral pathogens were conducted on 239 sera from 128 arabian oryx (oryx leucoryx) from seven locations (taif, riyadh and mahazat as said, saudi arabia; san diego, united states of america [usa]; shaumari, jordan; qatar; and bahrain). no antibodies to pasteurella multocida type e or epizootic haemorrhagic disease 1 virus were found. antibodies to brucella abortus, p. multocida type b, p. multocida type d, lumpy skin disease virus and akabane virus were ... | 1992 | 1305861 |
| similarity of chlamydia pneumoniae strains in the variable domain iv region of the major outer membrane protein gene. | dna was amplified by polymerase chain reaction from the gene encoding the major outer membrane protein (momp) of chlamydia pneumoniae in order to examine the relatedness of strains isolated from diverse geographical regions. primers for this reaction were chosen to span a 207-bp region comparable to that of the fourth variable segment of the momp gene of chlamydia trachomatis. among c. trachomatis, sequence heterogeneity is characteristic within variable sequence domain iv (vdiv) and correlates ... | 1992 | 1339411 |
| [biological products and laboratory reagents dehydrated by a rapid direct vacuum desiccation method. vi. studies of the preservation of microbial strains (c. burnetii, chlamydia psittaci, mycoplasma pneumoniae) and a laboratory reagent (para-nitrophenyl phosphate) by vacuum desiccation]. | 1992 | 1340260 | |
| biological properties and genetic analysis of the ompa locus in chlamydiae isolated from swine. | eight strains of chlamydia psittaci isolated from swine with pneumonia, pleuritis, pericarditis, and enteritis were characterized through analysis of the major outer membrane protein gene ompa by a two-step polymerase chain reaction, by their interactions with cells in culture, and by the morphologic features and ultrastructure of intracellular inclusions. amplified chlamydial ompa dna fragments were differentiated by restriction endonuclease digestion. chlamydial isolates were separated into 2 ... | 1992 | 1358014 |
| pcr detection and differentiation of chlamydia pneumoniae, chlamydia psittaci and chlamydia trachomatis. | a pcr-based system was developed for the detection and differentiation of chlamydia trachomatis, chlamydia psittaci and chlamydia pneumoniae. a conserved 145 bp fragment of the chlamydial omp1 gene was amplified from all three species. the three species were then differentiated from each other by digestion of this pcr product with restriction enzymes eco ri and either hind iii or pst i. the system was shown to work for two strains of c. pneumoniae, 11 strains of c. psittaci and 10 serovars of c. ... | 1992 | 1361961 |
| a synthetic glycoconjugate representing the genus-specific epitope of chlamydial lipopolysaccharide exhibits the same specificity as its natural counterpart. | the tetrasaccharide 3-deoxy-alpha-d-manno-2-octulosonic acid (alpha-kdo) (2----8)-alpha-kdo(2----4)-alpha-kdo(2----6)-beta glcnac, a partial structure of chlamydial lipopolysaccharide (lps) representing a genus-specific epitope, was synthesized and covalently linked to bovine serum albumin, resulting in an artificial glycoconjugate antigen. mice were immunized with the glycoconjugate to prepare chlamydia-specific monoclonal antibodies. they were selected with chlamydia-specific lps antigens and ... | 1992 | 1372290 |
| identification of chlamydia pneumoniae by dna amplification of the 16s rrna gene. | chlamydia pneumoniae is an important cause of respiratory disease in humans, but diagnosis of c. pneumoniae is hindered by difficulties in the in vitro growth of the organism. in order to improve detection and identification, we recently developed a polymerase chain reaction (pcr) assay which uses oligonucleotide primers specific for c. pneumoniae. the nucleic acid sequence was determined for the 16s rrna of c. pneumoniae, and regions in which c. pneumoniae differed from both chlamydia psittaci ... | 1992 | 1374077 |
| immunoelectron microscopy of chlamydia psittaci with monoclonal antibodies. | an immunoelectron microscopic study was performed to determine the distribution of antigenic components on particles of chlamydia psittaci and infected cells using a number of monoclonal antibodies (mabs). of three anti-lipopolysaccharide (lps) antibodies (4d5, a2 and 4g5), two antibodies (4d5 and a2) reacted with the surface of reticulate bodies (rbs) but not with that of elementary bodies (ebs). the other antibody (4g5) reacted with both ebs and rbs. examination of infected cells in thin secti ... | 1992 | 1374830 |
| detection and antigenicity of chlamydial proteins that bind eukaryotic cell membrane proteins. | chlamydia psittaci proteins capable of binding eukaryotic cell membranes were identified and antigenically characterized. cell membrane proteins (cmp) of noninfected cells were labeled with biotin (b-cmp), then were extracted with 1% triton x-100. nitrocellulose membrane strips containing sodium dodecyl sulfate-polyacrylamide gel electrophoresis-resolved proteins of chlamydial elementary bodies (eb) were reacted with the b-cmp extract, followed by addition of streptavidin-conjugated horse radish ... | 1992 | 1378251 |
| keratitis in free-ranging koalas (phascolarctos cinereus) on magnetic island, townsville. | seventy free-ranging koalas (phascolarctos cinereus) from magnetic island (queensland, australia) underwent an ocular examination, blood collection and serological examination for chlamydia psittaci antibodies, and an examination of their teeth and genitalia. in 12 koalas long-standing unilateral keratitis was noted and in another 10 animals long-standing bilateral keratitis was observed. all animals were seronegative for chlamydia psittaci and apart from some nasal discharge and a variety of as ... | 1992 | 1380994 |
| chlamydial endocarditis: a report on ten cases. | over the period 1983-1990, 10 cases of infective native-valve endocarditis as a result of chlamydia were seen. all patients were men, with a mean age of 42 years, and none had a history of exposure to chlamydia psittaci. symptoms, such as weight loss and anorexia, with fever in eight cases, had persisted for at least 2 months before admission. haemodynamic failure was present in seven patients, and neurological signs in four. the aortic valve was involved in seven cases, the mitral valve in one ... | 1992 | 1396819 |
| prevalence of chlamydia psittaci infection among persons who work with birds. | 1992 | 1399508 | |
| [familial outbreak of pneumonia by psittacosis]. | a familial outbreak (4 cases) of pneumonia by psittacosis in vall de uxó (castellón) during the month of april in 1990 is described. in addition to the epidemiologic, clinical and serologic (complement fixation) studies carried out a survey and serology of 11 healthy controls (neighbors, and employees from a bird shop) were performed. the serum of a parrot recently acquired by the patients (positive at 1/8) was analyzed. the habit of petting the animal was significantly associated with the disea ... | 1992 | 1405807 |
| protection against chlamydia psittaci in mice conferred by lyt-2+ t cells. | a murine model was used to study the respective roles of l3t4+ and lyt-2+ t cells in protection against chlamydia psittaci. donor mice were intravenously (i.v.) infected with 1 x 10(5) plaque-forming units (pfu) per mice of live c. psittaci. one month after inoculation, splenic cells from donors were transferred into syngenic recipients (5 x 10(7) cells/mouse). as measured by splenic colonization on day 6 after i.v. challenge (1 x 10(5) pfu/mouse), transfer with primed (untreated) cells conferre ... | 1992 | 1427980 |
| acquisition and synthesis of folates by obligate intracellular bacteria of the genus chlamydia. | we undertook studies focused on folate acquisition by chlamydia trachomatis l2, chlamydia psittaci 6bc, and c. psittaci francis. results from in situ studies, using wild-type host cells, confirmed that c. trachomatis l2 and c. psittaci 6bc are sensitive to sulfonamides whereas c. psittaci francis is resistant. in addition c. trachomatis l2 and c. psittaci francis were inhibited by methotrexate in situ whereas c. psittaci 6bc was not. in contrast to c. trachomatis, neither c. psittaci strain was ... | 1992 | 1430206 |
| [study on the bacteriological examination of sputum and bronchoscopy specimens from 31 cases with pneumonia due to chlamydia psittaci]. | we carried out the bacteriological examination of sputum and bronchoscopy specimens from 31 cases with pneumonia due to c. psittaci. the results obtained were as follows: 1. the positive culture of sputum and bronchoscopy specimens were 38.7% (12/31). 2. the organisms detected from them were 13 strains of gram-negative bacilli, 2 of gram-positive cocci and one gram-positive bacillus. 3. significant differences were observed in the white blood cell count between the cases of positive culture and ... | 1992 | 1431354 |
| culture of sheep chlamydia in a sheep fibroblast cell culture. | abortion and enteric isolates of chlamydia psittaci from sheep differed in their growth in a fibroblastic cell culture derived from the small intestine of a lamb. twenty abortion isolates, each from a different farm, produced large inclusions which could be passaged several times whereas 10 enteric isolates each from different farms (but from some of the farms of origin of the abortion isolates) produced sparse inclusions which could not be passaged. this appears to be a rapid method of distingu ... | 1992 | 1439220 |
| [epidemiology of micro-organisms responsible for community-acquired pneumonia]. | pneumonias occupy a prominent situation among lower respiratory tract infections where they are remarkable for their potential mortality and for our relative knowledge of the responsible micro-organisms. analysis and synthesis of each series published must answer several questions, such as: what are the lung diseases considered? which investigations have been performed? which criteria of imputability have been used? in which patients has the study been carried out? in which place, which period a ... | 1992 | 1439460 |
| enzyme electrophoretic polymorphism differentiates invasive from non-invasive chlamydia psittaci ruminant isolates. | a group of 24 chlamydia psittaci strains isolated from ruminants, belonging to serotype 1 and previously classified as invasive in a mouse model of virulence, was compared to a group of 10 non-invasive strains belonging to serotype 2 by using determination of glucose-6-phosphate and l-malate dehydrogenase zymotypes resulting of the infection of cells by these strains. the serotype 1 or invasive isolates represent a homogeneous group by sharing a unique zymotype which was not observed in the non- ... | 1992 | 1448629 |
| establishment of a particle-counting method for purified elementary bodies of chlamydiae and evaluation of sensitivities of the ideia chlamydia kit and dna probe by using the purified elementary bodies. | to evaluate the sensitivity of commercially available test kits for detection of chlamydiae, we established a method of purifying chlamydia trachomatis and chlamydia pneumoniae elementary bodies (ebs). we then subjected the purified ebs, together with the purified ebs of chlamydia psittaci, to the ideia chlamydia (ideia) and dna probe test kits to determine the eb numbers at the detection limits. the sensitivities of the test kits were thus compared. the results can be summarized as follows. (i) ... | 1992 | 1452662 |
| comparison of nine antigen detection kits for diagnosis of urogenital infections due to chlamydia psittaci in koalas. | chlamydia psittaci is the major cause of infectious disease in the koala (phascolarctos cinereus). it causes four disease syndromes in the koala, namely, conjunctivitis, rhinitis, cystitis, and infertility (females only). diagnosis of chlamydial infections in koalas relies primarily on isolation of the organism in cell culture. serology has generally not been useful, and little use has previously been made of the commercially available antigen detection kits. we examined the sensitivity, specifi ... | 1992 | 1452703 |
| isolation of chlamydia psittaci from pleural effusion in a dog. | 1992 | 1457552 | |
| preparation and use of a monoclonal antibody to detect chlamydia psittaci antigen in paraffin-embedded tissue sections. | a murine monoclonal antibody prepared against an ovine abortion isolate of chlamydia psittaci (a22/teramo) revealed specific binding to a 57 kda chlamydial antigen in immunoblotting studies. the monoclonal antibody was able to detect intracytoplasmic chlamydial inclusions and scattered elementary bodies in infected mccoy cell culture, and on formalin-fixed paraffin-embedded tissue sections both from experimentally infected mice and from fetal membranes of cases of ovine enzootic abortion. | 1992 | 1465516 |
| [the signal transduction mechanism responsible for interferon-gamma-inducible indoleamine 2,3-dioxygenase (ido) gene expression in t98g cells]. | the interferon (ifn)-gamma-induced indoleamine 2,3-dioxygenase (ido) is implicated in the inhibition of intracellular pathogens, e.g. chlamydia psittaci and toxoplasma gondii. the intracellular signaling molecules responsible for the induction of ido gene expression were investigated by the quantitative polymerase chain reaction. the gene expression was inhibited by a tyrosine kinase inhibitor, genistein. being consistent with this, ifn-gamma induced increased tyrosine phosphorylation and this w ... | 1992 | 1469778 |
| specificity of the microimmunofluorescence assay for the serodiagnosis of chlamydia pneumoniae infections. | chlamydia pneumoniae infections are mostly confirmed using an indirect microimmunofluorescence test for which potential cross-reactions between antigens from different chlamydial species are not well documented. using this assay, 928 sera (507 subjects) submitted for chlamydia pneumoniae serology were tested for specific igm and igg to this bacteria using the tw-183 antigen. igm and igg reactivities to chlamydia trachomatis serotypes c, d, e, and l2 and chlamydia psittaci strain 6bc antigens wer ... | 1992 | 1477792 |
| [bilateral pneumonia caused by chlamydia psittaci. description of a clinical case]. | a mortal case of atypical pneumonia due to chlamydia psittaci with acute respiratory distress, septic shock and multiple organ failure is described. infection has been caused by an ill parrot imported clandestinely. antibody titration with the immunofluorescence technique allowed diagnosis. | 1992 | 1508365 |
| ophthalmologic examination of the normal eye of the koala. | the ophthalmic examination of the koala (phascolarctos cinereus) was undertaken to describe the normal in vivo structure. twenty-two of 28 koalas examined were found to have normal eyes. slit-lamp examination revealed unusual lamellae in the cornea, and mean keratometric readings were 59.3 +/- 3 diopters, corneal endothelial cell area of 381.4 microns2 +/- with a standard deviation of 46.8 microns2. no particular features were seen which would explain the susceptibility of this animal to ocular ... | 1992 | 1512874 |
| serologic survey for selected arboviruses and other potential pathogens in wildlife from mexico. | during 1988 and 1989, a serologic survey of wildlife was conducted in northeastern mexico to determine the presence, prevalence, and distribution of arboviruses and other selected disease agents. eighty mammal specimens were tested. antibodies to vesicular stomatitis-indiana, venezuelan equine encephalitis-mena ii, rio grande virus, and vesicular stomatitis-new jersey were detected predominantly in small mammals. deer and mouflon (ovis musimon) had antibodies to bluetongue and epizootic hemorrha ... | 1992 | 1512876 |
| monoclonal antibody based capture elisa/elifa for the detection of chlamydia psittaci in veterinary clinical specimens. | a capture elisa/elifa system based on monoclonal capture and biotinylated monoclonal detection antibody with specificity for an epitope on chlamydial lipopolysaccharide (lps) is described. the assay is fast, specific and detects a minimum dose of approximately 2000 chlamydial particles (c. psittaci). unlike other commercially available test kits, it comprises a proteinase k treatment to exclude non-specific binding of antibodies to fc receptors. in contrast to the sophisticated and cumbersome is ... | 1992 | 1520968 |
| pneumonia due to legionella bozemanii and chlamydia psittaci/twar following renal transplantation. | chlamydia and legionella are recognized causes of atypical pneumonia. a case of pneumonia due to chlamydia psittaci/twar and legionella bozemanii following renal transplantation is described. legionella bozemanii infection was diagnosed by a rise in antibodies and by isolation of the organism from bronchoscopy specimens. it is unusual to find pneumonia caused concomitantly by two such agents. this case, despite the fatal outcome, emphasises the necessity for a comprehensive approach to the diagn ... | 1992 | 1522325 |
| ovine chlamydiosis in an abattoir worker. | the strain of chlamydia psittaci causing enzootic abortion in ewes (the eae strain) may cause serious infection in pregnant women, often resulting in hepatic and renal dysfunction, disseminated intravascular coagulation and fetal loss. the first case of such an infection in an abattoir worker is described and the possibility of human-to-human transmission considered. direct handling of sheep or their products of conception can usually be established but this is not always so. there is much still ... | 1992 | 1522332 |
| coxiella burneti endocarditis in a patient with positive chlamydial serology. | a 41-year-old man who habitually slept in a car park presented with a culture-negative endocarditis. serological tests indicated infection with both coxiella burneti and chlamydia psittaci. he was treated with doxycycline and clindamycin and required aortic valve replacement. culture of the excised value for both agents was negative but electron microscopy was suggestive of coxiella endocarditis. | 1992 | 1522334 |
| the differentiation of chlamydia species by antigen detection in sputum specimens from patients with community-acquired acute respiratory infections. | an amplified enzyme immunoassay (ideia iii: dako diagnostics ltd) for detecting genus-specific chlamydia antigen was evaluated prospectively on 286 respiratory specimens from 275 patients presenting with community-acquired pneumonia or persistent chest infection. nineteen patients had evidence of recent chlamydial infection, having two or more positive sputum or serological markers. sputa from two other patients were elisa-positive in the absence of other positive criteria and were regarded as f ... | 1992 | 1522342 |
| a comparison of the seroepidemiology of chlamydial infection in pigeon fanciers and farmers in the u.k. | a detailed comparative seroepidemiological study of antibody responses was performed in 271 pigeon fanciers and 100 farmers. overall 73% of pigeon fanciers had igg antibodies at a titre greater than or equal to 16 to chlamydia pneumoniae, 39% to chlamydia psittaci, and 6.6% to chlamydia trachomatis. the prevalence of chlamydial antibodies was significantly lower in the farmers at 47% for c. pneumoniae, 6% for c. psittaci, and 2% for c. trachomatis. both populations were exposed to complex microb ... | 1992 | 1522344 |
| detection of chlamydia pneumoniae by polymerase chain reaction. | while criteria for serodiagnosis of chlamydia pneumoniae infection are well established, isolation of the organism is often difficult. to increase detection of this organism, c. pneumoniae-specific sequences were identified to permit amplification of c. pneumoniae by polymerase chain reaction (pcr). a cloned c. pneumoniae 474-bp psti fragment was shown by dot blot and southern hybridization to differentiate c. pneumoniae from the other chlamydia spp., react with all c. pneumoniae isolates tested ... | 1992 | 1537913 |
| l-arginine-dependent reactive nitrogen intermediates and the antimicrobial effect of activated human mononuclear phagocytes. | the l-arginine-dependent generation of reactive nitrogen intermediates (rni) has been identified as a key intracellular antimicrobial mechanism of activated mouse macrophages. to determine the role of this mechanism in the activity of human mononuclear phagocytes, monocyte-derived macrophages activated in vitro by interferon (ifn)-gamma and monocytes from patients receiving ifn-gamma as therapy were treated with ng-monomethyl-l-arginine (nma) or arginase. neither competitive inhibition of l-argi ... | 1992 | 1538156 |
| interspecies structural diversity among chlamydial genes encoding histone h1. | recently, a eukaryotic histone h1-like protein has been detected in chlamydia trachomatis serovar l2 [hackstadt et al., proc. natl. acad. sci. usa 88 (1991) 3937-3941; tao et al., j. bacteriol. 173 (1991) 2818-2822]. we have cloned the corresponding gene from c. trachomatis serovar j and the chlamydia psittaci strain mn. sequencing demonstrated absolute gene identity between the two c. trachomatis serovars l2 and j, but divergence in the c. psittaci strain mn. these differences resulted in alter ... | 1992 | 1551591 |
| brief report: chlamydia psittaci endocarditis diagnosed by blood culture. | 1992 | 1557094 | |
| antigenic and morphological differentiation of placental and intestinal isolates of chlamydia psittaci of ovine origin. | ewe placental and lamb intestinal isolates of chlamydia psittaci recovered from flocks affected with ovine enzootic abortion were examined by inclusion morphology, indirect immunofluorescence (iif) and immunoblot analysis. chlamydiae recovered from the faeces of sheep from two flocks free of clinical disease were also examined. in cell culture ovine abortion (oa) and intestinal isolates were distinguishable by inclusion development and morphology. similarly, in two-way iif tests with one week mo ... | 1992 | 1557895 |
| [multicausal infectious respiratory tract disease of young fattening turkeys]. | the outbreak of the disease occurred in a large multiple-age farm with about 50,000 meat turkeys, where groups of 6-8000 one-day-old birds were stalled up every 14 days. all the turkey poults housed were affected mostly in the 1.-3. week of the life. the respiratory disease spread rapidly within the flocks and were characterised clinically by inclination of huddle, ruffled feathers, anorexia, stunted growth, swelling of the infraorbital sinus and nasal discharge. the clinical apparent disease la ... | 1992 | 1559465 |
| pathogenesis of endometritis and salpingitis in a guinea pig model of chlamydial genital infection. | the development of tubal obstruction and subsequent infertility is a major sequelum of upper genital tract infection with chlamydia trachomatis; however, little is known about the pathogenesis of the infection. in this investigation, the authors present a detailed study of the progression of ascending chlamydial infection in female guinea pigs resulting from intravaginal inoculation of the chlamydia psittaci agent of guinea pig inclusion conjunctivitis (gpic). isolation of chlamydiae from differ ... | 1992 | 1562052 |
| effects of interferons beta or gamma on neopterin biosynthesis and tryptophan degradation by human alveolar macrophages in vitro: synergy with lipopolysaccharide. | interferons can induce neopterin biosynthesis and tryptophan degradation in monocytic cells. indoleamine 2,3-dioxygenase (ido), an inducible cellular enzyme, metabolizes tryptophan to n-formyl-l-kynurenine. tryptophan degradation has been linked to interferon-mediated inhibition of replication by intracellular pathogens and inhibition of cancer cell proliferation. we evaluated the ability of the recombinant human interferons beta ser and gamma to stimulate neopterin production and tryptophan deg ... | 1992 | 1591013 |
| [rational means of the determination of costs and etiological diagnosis of community-acquired pneumonia]. | the cost and effectiveness of examinations (sputum staining and culturing, antitest determination for influenza a and b, rsv, adenovirus, chlamydia psittaci and pneumoniae, coxiella burnetii, mycoplasma pneumoniae and legionella pneumophila, and determination for streptococcus pneumoniae antigen) performed to explore the aetiology of community-acquired pneumonia in the case of 258 hospitalised patients were analysed. the aetiology could be determined in 44.2% of the cases. on the basis of prevai ... | 1992 | 1608606 |
| chlamydia psittaci infection in horses: results of a prevalence survey and experimental challenge. | nasal and conjunctival swabs were obtained from 300 horses and chlamydia psittaci was isolated from 15 of them (5 per cent). eleven nasal swabs and six conjunctival swabs were positive on culture, but there was no association between the isolation of the organism and the presence of clinical ocular or respiratory disease. six ponies were challenged with an equine isolate of c psittaci into the eye, nasal cavity or bronchial tree. the organism could be isolated from nasal and conjunctival swabs t ... | 1992 | 1609475 |
| evaluation of a commercial solid-phase enzyme immunoassay for the detection of ovine chlamydia psittaci. | 1992 | 1616986 | |
| diagnosis of avian chlamydiosis: specificity of the modified giménez staining on smears and comparison of the sensitivity of isolation in eggs and three different cell cultures. | for the diagnosis of chlamydiosis in dead and live birds different methods were compared for their sensitivity and specificity. the specificity of the modified giménez staining and the direct immunofluorescence (dif) test for direct demonstration of chlamydia psittaci in organ, cloacal and/or conjunctival smears was examined. the sensitivity of the isolation of chlamydia psittaci in 6 days embryonated specific pathogen free (spf) chicken eggs, buffalo green monkey (bgm) cell line, mccoy cell lin ... | 1992 | 1621472 |
| acute glomerulonephritis following infection with chlamydia psittaci. | 1992 | 1621687 | |
| [latent chlamydia infections as the cause of health disorders in swine, cattle and sheep breeders in czechoslovakia]. | for a twelve year period the health condition of a large group of pig-, cattle- and sheep-breeder was controlled and at the same time an inquiry was carried out why these people suffer from high occurrence of specific health problems which among the rest of the population appear in smaller extent. the performed investigation shows that the primary cause of the specific problems is a latent infection caused by the chlamydia microorganism, namely by the chlamydia trachomatis group, that can be tra ... | 1992 | 1622377 |
| [results of studies with aborted cattle fetuses]. | the laboratory of the animal health service of south holland investigated 2410 cases of spontaneous abortion (twins (112) were considered one case). seventy-eight afterbirths without foetuses were also examined. the aim of the study was not only to find the cause of abortion but also to see whether there was a relation between the results of the different bacteriological, virological and histological tests used. the presence of igg in the blood of foetuses older than 5 months was also determined ... | 1992 | 1626316 |
| restriction endonuclease analysis of dna from ruminant chlamydia psittaci and its relation to mouse virulence. | dna from 20 pathogenic or non-pathogenic ruminant strains of chlamydia psittaci was compared by restriction endonuclease analysis. the strains could be easily differentiated according to their invasiveness for mouse, whatever their pathological origin. dna patterns of invasive strains were similar, whereas those of non-invasive strains were distributed in two groups. | 1992 | 1626375 |
| [coxiella burnetii and chlamydia psittaci infection in dogs]. | the prevalence of coxiella burnetii and chlamydia psittaci antibodies was investigated in 530 dog specimens divided into six groups, i. e. a = private watch dogs, b1 = service dogs from bratislava, b2 = service dogs from other localities of slovakia and moravia, c = watch dogs from farms, i = household dogs, t = stray dogs. the dogs demonstrated the higher seropositivity to c. burnetii (11.7%) than to ch. psittaci (5.5%). the highest percentage of antibodies to c. burnetii was found in stray dog ... | 1992 | 1641947 |
| ultrastructural studies of chlamydia-infected air sacs of chicks. | the air sac of chicks inoculated with chlamydia psittaci was examined ultrastructurally. the epithelial cells had minute chlamydial inclusion bodies consisting of a few reticulate bodies in the initial stages of infection. in the epithelial cells in the early and middle stage of infection, small- to medium-sized chlamydial inclusion bodies were found in the cytoplasm adjacent to the golgi apparatus and surrounded with many mitochondria. the cytoplasm having chlamydial inclusion bodies was rich i ... | 1992 | 18670959 |
| tetracyclines-extending the atypical spectrum. | the main features and the present position of tetracyclines are reviewed. the mechanism of their action, bacterial resistance and the most recent findings are reported. their decreased use is due to the availability of new, active, better-tolerated antibiotics. however, tetracyclines still have a place in the treatment of chlamydial and rickettsial infections, brucellosis and lyme disease. in respiratory infections, they can be employed when necessary in infections caused by chlamydia psittaci, ... | 1993 | 18611577 |
| neutralization of chlamydia psittaci with monoclonal antibodies. | neutralization of chlamydia (c.) psittaci avian strain p-1041 was examined in vitro using monoclonal antibodies (mabs). of the 10 mabs used, 6 were found to exhibit neutralizing capability. these include 3 against major outer membrane protein (momp), 1 against lipopolysaccharide (lps) and 2 against other protein molecules [90 kilodalton (kda) and 90/50 kda]. most neutralizing mabs were dependent on complement for efficient neutralization, while a strain-specific mab (2b5) against the 90 kda prot ... | 1993 | 7507199 |
| the genus-specific lipopolysaccharide epitope of chlamydia is assembled in c. psittaci and c. trachomatis by glycosyltransferases of low homology. | chlamydiae possess a genus-specific epitope that is located on the lipopolysaccharide (lps) and is composed of a 3-deoxy-d-manno-octulosonic acid (kdo) trisaccharide of the sequence alpha kdo-(2-->8)--alpha kdo-(2-->4)-alpha kdo. in chlamydia trachomatis, this trisaccharide is biosynthetically generated through the action of a multi-functional kdo-transferase encoded by the gene gsea. gsea of chlamydia psittaci 6bc was cloned and expressed in a rough mutant (re chemotype) of escherichia coli (st ... | 1993 | 7523826 |
| characterization of a neutralizing monoclonal antibody directed at variable domain i of the major outer membrane protein of chlamydia trachomatis c-complex serovars. | a monoclonal antibody (mab), c10, that neutralized in vitro the infectivity of serovars c, i, j, and l3 (members of the c and c-related complexes) of chlamydia trachomatis was identified. of the 15 major serovars and the mouse pneumonitis strain of c. trachomatis, chlamydia psittaci, and chlamydia pneumoniae, which were used as nontreated and heat-treated (56 degrees c, 30 min) antigens in a dot blot assay, only serovars c, i, j, and l3 were recognized with both the native and treated antigens. ... | 1993 | 7681045 |
| some aspects of the immune response of koalas (phascolarctos cinereus) and in vitro neutralization of chlamydia psittaci (koala strains). | western-blot analysis was used to study the reaction of koala antisera, two specific polyclonal antibodies and one monoclonal antibody, with chlamydial antigens in koalas infected with chlamydia psittaci. the koala sera recognized four c. psittaci surface antigens, corresponding to the major outer membrane protein (39.5 kda), 31 kda protein, 18 kda protein and lipopolysaccharide. the s25-23 lps specific monoclonal antibody inhibited chlamydial infection (55-67%) with both koala strains (type i a ... | 1993 | 7682465 |
| chlamydial infection of the respiratory tract. | chlamydial infection of the human respiratory tract was first described over 100 years ago, when outbreaks of psittacosis were linked to imported pet birds. the causative organism was identified subsequently as chlamydia psittaci. however, c. pneumoniae, has also been recognised recently as an important cause of human respiratory tract infection. approximately 300 cases of human chlamydial respiratory tract infection are reported to cdsc each year, mainly in adults aged 15 to 44 years. a prospec ... | 1993 | 7693170 |
| the evidence of circulation of some viruses in a great town of romania during the first half of 1992. | complex serological survey performed in the town b. during the first half of 1992 emphasized an active circulation of some respiratory viruses, especially of parainfluenza type 3 and 1, influenza subtypes a(h3n2) and a(h1n1), adeno and syncytial respiratory as well as of mycoplasma pneumoniae. less important was the frequence of antibodies against chlamydia psittaci, east equine, west nile and tick-borne encephalitis as well as parainfluenza type 2 and influenza type b viruses. | 1993 | 7826877 |
| expression and translocation of the chlamydial major outer membrane protein in escherichia coli. | the entire gene encoding the major outer membrane protein (momp) from chlamydia psittaci strain gpic has been cloned and expressed in escherichia coli. a tightly regulated t7 promoter is used to control expression of the protein in escherichia coli. upon induction of expression, the precursor (pre-momp) is synthesized in the cell. this is followed by the appearance of a lower molecular weight protein that comigrates with mature momp from chlamydial elementary bodies by both one-dimensional sodiu ... | 1993 | 7911969 |
| resolution of murine chlamydial genital infection by the adoptive transfer of a biovar-specific, th1 lymphocyte clone. | mopn-specific t-cell clones were isolated from a t-cell line that was capable of curing chlamydial genital infection by the chlamydia trachomatis agent of mouse pneumonitis (mopn) after adoptive transfer. two clones (designated as 2.14-0 and 2.14-3) were characterized by flow cytometry techniques to be homogenous for l3t4, cd3, and alpha/beta t cell receptor (tcr) t-helper cell markers. the two clones were biovar specific, because they reacted to mopn but not the chlamydia psittaci agent of guin ... | 1993 | 8068534 |
| primary pathogenicity of an european isolate of chlamydia psittaci from turkey poults. | chlamydia psittaci was isolated as the sole pathogenic agent from a severe outbreak of respiratory disease in a commercial broiler turkey farm in the netherlands. the mortality rate in the flocks was 65%. clinical signs included conjunctivitis, swelling of the sinus infraorbitalis and sneezing. cloacal excretion of chlamydia was demonstrated in twelve out of fifteen birds examined by a direct immunofluorescence test. in all the fifteen birds antibodies against chlamydia psittaci were detected in ... | 1993 | 8128594 |
| rapid diagnosis of chlamydia psittaci pneumonia. | two cases of chlamydia psittaci pneumonia are presented. in each, a rapid diagnosis was made through the use of direct immunofluorescent antibody staining of respiratory secretions with monoclonal antibodies to chlamydial antigens. in one case the diagnosis was confirmed by the isolation of the causative organism from sputum and a pharyngeal swab. chlamydial lipopolysaccharide was detectable in sputum from this patient in an enzyme immunoassay. serological responses to c. psittaci, chlamydia tra ... | 1993 | 8218673 |
| [enrofloxacin (baytril)--an alternative for psittacosis prevention and therapy in imported psittacines]. | it was the aim of the presented work to test enrofloxacin under field conditions of compulsory prophylaxis and treatment of psittacosis, as jung (1993) had already demonstrated the effectiveness of this antibiotic against chlamydia psittaci. during official quarantine 22 groups comprising 2536 birds were treated with baytril. with suitable feed like steamed maize and a dose of 500 mg/kg enrofloxacin the mean blood values ranged from 0.9 to 4.1 micrograms/ml within the different species. applicat ... | 1993 | 8223239 |
| clinical and laboratory findings in chronic conjunctivitis in cats: 91 cases (1983-1991). | clinical findings and laboratory test results from 91 cats with chronic conjunctivitis were studied to determine the causes of the disease and the sensitivity of diagnostic procedures used, and to identify correlations between results of various diagnostic procedures and clinical or signalment variations. mean age of affected cats was 2.9 +/- 2.7 years (+/- sd), with a range from 1 month to 11 years. conjunctivitis was more likely to be bilateral (56 cats) than unilateral (35 cats). in cats test ... | 1993 | 8226238 |
| feline bordetellosis: challenge and vaccine studies. | four eight-week-old cats, shown to be free from feline calicivirus, feline herpesvirus and chlamydia psittaci were challenged with an aerosol of bordetella bronchiseptica. within five days the cats developed signs of respiratory disease, characterised by nasal discharge, sneezing, spontaneous or induced coughing and dry or wet rales at auscultation. these signs were present for about 10 days, after which they began to resolve. to test the protective capacity of an experimental fimbrial antigen-b ... | 1993 | 8236648 |
| comparison of different serological methods for the determination of antibodies to chlamydia psittaci in pigeon sera. | several methods for detecting antibodies to chlamydia psittaci using sera from pigeons were compared with regard to their sensitivity, specificity and efficacy. the reference method used was indirect immunofluorescence (ifi), which uses as antigen intracellular inclusions in mccoy cell monolayers. indirect micro-immunofluorescence (mif) using as antigen c. psittaci cultured on yolk sacs of embryonated eggs, direct and indirect complement fixation tests (cft and icft, respectively), and enzyme-li ... | 1993 | 8237193 |
| an epidemic of avian and human psittacosis. | psittacosis may occur in epidemic or sporadic form. we report an outbreak of avian and human psittacosis associated with an aviary in philadelphia, pa. the epidemic spread among birds in the aviary and then to men and women who were in contact with the birds. chlamydia psittaci was cultured from infected birds, and the human patients were evaluated clinically and serologically. after proper treatment of the birds, cleaning of their cages, and institution of appropriate bird-handling techniques, ... | 1993 | 8239852 |
| serologic survey for selected viral and rickettsial agents of brown bears (ursus arctos) in croatia. | sera from 22 (13 wild and nine captive) european brown bears (ursus arctos) from croatia were tested to 18 viral and rickettsial agents. serologic evidence of exposure was found to the following agents (number positive/number examined): bhanja virus (3/15), tahyna virus (3/15), west nile virus (4/15), naples sandfly fever virus (1/15), human adenovirus (1/22), influenza a (1/22) and b (1/22) virus, cytomegalovirus (1/22), parainfluenza virus 1 (2/22), chlamydia psittaci (1/22), coxiella burnetii ... | 1993 | 8258856 |
| restriction fragment length polymorphisms of rrna as genetic markers to differentiate chlamydia spp. | restriction fragment length polymorphisms (rflps) of rrna genes of chlamydia spp. were analyzed. a southern analysis of chromosomal dna digests with cloned rrna gene probes revealed the presence of one locus for rrna genes on chromosomal dnas in chlamydia psittaci, chlamydia pecorum, and chlamydia pneumoniae and two loci in chlamydia trachomatis. the rflps of rrna genes were characteristic for each chlamydia sp. dna probes cloned from flanking regions of the rrna genes of avian c. psittaci hybri ... | 1993 | 8102247 |
| a rickettsia-like organism from ixodes uriae ticks collected on the kerguelen islands (french subantarctic territories). | a rickettsia-like microorganism was isolated in suckling mice from ixodes uriae ticks collected from penguins breeding on mayes island, kerguelen archipelago, french subantarctic territories. at isolation, this agent mimicked a tick-borne arbovirus. finally, electron microscopy studies of infected suckling mouse livers showed the presence of inclusions filled with pleomorphic microorganism in the cytoplasm of some hepatocytes, sometimes dividing by binary fission and thus of obviously non-viral ... | 1993 | 8105647 |