Publications

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biology of the human malignant lymphomas. i. establishment in continuous cell culture and heterotransplantation of diffuse histiocytic lymphomas. 19744140017
activation of mammalian leukemia viruses. 19744140683
demonstration of epstein-barr virus-associated nuclear antigen in nasopharyngeal carcinoma cells from fresh biopsies. 19744142471
case records of the massachusetts general hospital. weekly clinicopathological exercises. case 28-1974. 19744134679
differentiation between early and late membrane antigen on human lymphoblastoid cell lines infected with epstein-barr virus. ii. immunoelectron microscopy. 19744134855
hodgkin's disease 1974. 19744135116
epstein-barr virus-associated complement-fixing and nuclear antigens in burkitt lymphoma biopsies. 19744136722
membrane antigens characteristic of human lymphoid cells in established cultures. 19744137060
relationship between epstein-barr virus (ebv) dna and the ebv-determined nuclear antigen (ebna) in burkitt lymphoma biopsies and other lymphoproliferative malignancies. 19744137165
human leukocyte locus a (hl-a) antigens and infectious mononucleosis. 19744137707
atypical lymphocytes in acute infectious mononucleosis. identification by multiple t and b lymphocyte markers. 19744138509
stimulation of herpesvirus saimiri expression in the absence of evidence for type c virus activation in a marmoset lymphoid cell line.nucleic acid base analogues were used to examine a herpesvirus saimiri (hvs)-infected marmoset lymphoid cell line (mlc-1) for possible association with type c viruses. synthetic templates poly(ra).d(pt)(10) and poly(da).d(pt)(10) were used to detect rna-directed dna polymerase activity in 100-fold concentrated tissue culture fluids. hvs was monitored by immunofluorescence for early, late, and membrane antigens. mlc-1 cells were exposed to 30 mug of 5-bromo-2'-deoxyuridine (budr) per ml for 24 h ...19744138895
letter: cytomegalovirus in non-b post-transfusion hepatitis. 19744139618
editorial: infectious (?) myasthenia. 19744139654
letter: ebv and american burkitt's lymphoma. 19744360497
anti-epstein barr virus antibody in nasopharyngeal carcinoma. 19744359674
familial medullary thyroid carcinoma and pheochromocytoma: epidemiologic investigations. 19744359415
epstein-barr virus infection in the neonatal period and in childhood.in an attempt to detect and characterize congenital, neonatal and early childhood ebv infections, a prospective sero-epidemiological study was undertaken in 112 newborn infants and their mothers, 25 additional newborns undergoing exchange transfusion, 114 randomly selected hospitalized infants aged 0 to 3 years, and 109 siblings and parents of these infants. leukocyte culture was attempted in all the newborns and in 25 pre- and post-transfusion.the findings of ebv seroconversion in six patients ...19744358534
epstein-barr virus infections. 19744358535
fatal infectious mononucleosis in a family. 19744358992
epstein-barr virus antibodies in the cerebrospinal fluid. a case of infectious mononucleosis with encephalitis. 19744359097
integration of epstein-barr virus dna into cellular dna of burkitt lymphoblasts (raji cell line). 19744443223
human leukemia-associated anti-nuclear reactivity.a brilliant, coarsely granular nuclear antigen was detected by anti-complement immunofluorescence in the nuclei of acute myeloid leukemia myeloblasts. designated as lana (leukemia-associated nuclear antigen), the reactivity differs from that of the epstein-barr-virus-determined nuclear antigen (ebna) in immunological specificity and morphological appearance, although it is visualized by the same method. serum from acute myeloid leukemia patients gave positive reactions in 73% of the cases. in ac ...19744595570
t- and b-lymphocytes in immunological disorders.the lymphocytes from the patients with primary immunodeficiency diseases and those under immunosuppressive conditions such as viral infection or administration of antimetabolites were studied by various parameters of t- and b-lymphocytes. t-lymphocyte specific antigen, spontaneous rosette formation with sheep erythrocytes, phytohaemagglutinin response of the lymphocytes and delayed hypersensivity skin reaction were used to assess t-lymphocytes, while complement receptor, surface immunoglobulin, ...19744377862
chromosomal integrity of cell substrates--a safety consideration. 19744377881
divergent properties of two human lymphocytic cell lines isolated from a single specimen of peripheral blood. 19744377927
cytolytic properties of phallolysin. 19744376795
infection of ebv-genome-negative and -positive human lymphoblastoid cell lines with biologically different preparations of ebv.epstein-barr virus (ebv) derived from the b95-8 line has transforming activity for cord blood cells, whereas virus derived from the p3hr-1 line lacks such activity. when the two viral preparations were compared for their ability to infect the same ebv-genome-negative lymphoblastoid cell line, bja-b, they induced approximately the same number of ebv-determined nuclear antigen (ebna)-positive cells. ebna is compatibile with continued cell proliferation. no early antigen (ea)-positive cells appeare ...19744376804
control mechanisms in infectious mononucleosis. 19744377556
cell relationships in transformation of human leukocytes by epstein-barr virus. 19744376505
segregation of the ebv-determined nuclear antigen (ebna) in somatic cell hybrids derived from the fusion of a mouse fibroblast and a human burkitt lymphoma line. 19744376508
herpesvirus ateles: transformation in vitro of marmoset splenic lymphocytes. 19744376514
early events in transformation of human cord leukobytes by epstain-barr virus: induction of dna synthesis, mitosis and the virus-associated nuclear antigen synthesis. 19744376517
cytotoxic antibodies to cultured lymphoblasts unrelated to epstein-barr virus. 19744376526
the history of infectious mononucleosis. 19744363554
antibodies to epstein-barr virus-associated antigens in relatives of cancer patients. 19744363700
b-cell characteristics of human peripheral and cord blood lymphocytes transformed by epstein-barr virus. 19744363701
procedure for activating epstein-barr virus early antigen in nonproducer cells by 5-iododeoxyuridine. 19744363712
cytomegalovirus antibody in uremic patients prior to renal transplantation. 19744364098
asymptomatic infection with eb virus.evidence of asymptomatic eb virus infection was sought in healthy medical students and nurses following the observation that 1.4% possessed heterophile antibodies. the proportion of subjects with eb virus antibodies rose with age and there was evidence of recent infection in 19%. smooth muscle antibodies were detected in 13 individuals and recent infection with eb virus was probable in six of these. subclinical eb virus infections, in some cases associated with some disturbance of immunological ...19744363378
limitations of immunofluorescence tests in the diagnosis of infectious mononucleosis.the relative value of heterophil agglutinins (ha) and of specific ebv antibodies in the diagnosis of infectious mononucleosis (im) was assessed in 108 cases of the disease and in 280 controls. among the 108 cases 93 were ha-positive by sheep cells in at least one of their sera, while 15 were ha-negative by the same test. among the 280 controls false-positive ha tests were not encountered except in eight cases with the horse cell microtitre tests. with one of the two slide tests at least two fals ...19744363398
epstein-barr virus-negative human malignant t-cell lines.two lymphoblastoid lines, ccrf-cem and hsb-2, with properties of malignant cells, derived from children with leukemia secondary to lymphosarcoma, have t-cell properties and lack epstein-barr virus antigens.19744363409
[current views on the viral origin of cancer]. 19744363460
abnormalities in the mixed leukocyte reaction during infectious mononucleosis. 19744363510
control of interferon, migration inhibition factor, and expression of virus capsid antigens in burkitt's lymphoma-derived cell lines: role of l-arginine.the effects of an arginine-utilizing mycoplasma, mycoplasma arginini, and of varying levels of arginine in the growth media of the epstein-barr virus (ebv)-containing eb1 and eb3 cell lines, and the ebv-free rpmi 1788 cell line, were studied. l-arginine, at a concentration of 0.1 mm in the growth medium, led to a reduction of the ebv capsid antigen content of the eb1 and eb3 cells lines as determined by indirect immunofluorescence, and m. arginini infection enhanced this reduction. the synthesis ...19744362772
human cytomegalovirus. ii. lack of relatedness to dna of herpes simples i and ii, epstein-barr virus, and nonhuman strains of cytomegalovirus.the purified dna of human cytomegalovirus, radiolabeled in vitro, was examined for homology to epstein-barr virus, herpes simplex type i and ii, and simian and murine cytomegalovirus dna by dna-dna reassociation kinetics analyses with the s1 enzyme differential digestion technique. cross-matching of the dnas showed no relatedness or less than 5% detectable homology.19744362866
childhood non-hodgkin's lymphoma--a study of 17 cases in israel. 19744362957
immunological reactions in kuru. attempts to demonstrate serological relationships between karu and other known infectious agents. 19744363040
herpesvirus and epstein-barr virus antibodies and carcinoma of the intrinsic larynx. 19744361787
the epstein-barr virus (ebv) in burkitt's lymphoma and nasopharyngeal carcinoma. 19744362218
proceedings: a new look at the eb virus and oncogenesis. 19744362450
enhanced activation of the repressed epstein-barr viral genome by inhibitors of dna synthesis. 19744362552
eb virus-associated antibodies in caucasian patients with carcinoma of the nasopharynx and in long-term survivors after treatment. 19744362609
comparison of ebv neutralization tests based on abortive infection or transformation of lymphoid cells and their relation to membrane reactive antibodies (anti-ma). 19744362610
epstein-barr virus: transformation of non-human primate lymphocytes in vitro. 19744362611
subacute sclerosing panencephalitis. elevated epstein-barr virus antibody titers and failure of amantadine therapy. 19744362620
replication of the resident repressed epstein-barr virus genome during the early s phase (s-1 period) of nonproducer raji cells.replication of the resident repressed epstein-barr virus genome in synchronized nonproducer raji cells was shown to occur during the early s phase (s-1 period) by hybridization of cell dna with virus-specific complementary rna (crna). the s-1 period was previously identified as the critical period for virus activation induced by thymidine analogues. the findings reported here and elsewhere are consistent with the proposal that: (i) virus activation is initiated at or near the site of association ...19744362625
complement-fixing antibodies reactive with epstein-barr virus in sera of marmosets and prosimians. 19744360647
infectious mononucleosis and epstein-barr virus in childhood. 19744360931
homology between burkitt herpes viral dna and dna in continuous lymphoblastoid cells from patients with infectious mononucleosis.at least 90% of the sequences of purified, in vitro labeled, dna from epstein-barr virus (prepared from hr-1, burkitt's lymphoblastoid cells) are homologous to the dna of the herpes virus contained in cell lines derived from patients with infectious mononucleosis. the thermal stability of the homologous and heterologous hybrid dna molecules could not be differentiated, indicating at least 97% matching of base pairs between dna of epstein-barr virus and the herpes viral dna contained in the lymph ...19744360941
down's syndrome: establishment of lymphoblastoid cell lines with trisomy 21. 19744361078
detection of antigens determined by the epstein barr virus (ebv) in human lymphoblastoid cell culture lines by elution of specific radioiodine labeled antibody. 19744361279
[cancer of the rhinopharynx. a rare cancer]. 19744361514
differentiation between early and late membrane antigen on human lymphoblastoid cell lines infected with epstein-barr virus. i. immunofluorescence. 19744365906
eb virus and the treatment of lymphomas.the high incidence of eb virus infections (and possibly of other viruses) in patients with african lymphoma and, to a lesser extent, in patients with lymphosarcoma in the temperate zones, is thought to be due to its being a passenger virus which persists in the human body and, since it is lymphotropic, presents an opportunistic infection of proliferating lymphoid cells. the thesis is put forward that by entering the cell nucleus, the virus renders malignant lymphoid cells more vulnerable to cyto ...19744365959
letter: unsuspected cytomegalic mononucleosis. 19744365960
oncogenic dna viruses of nonhuman primates: a review. 19744366130
[latency and reactivation of herpes group viruses]. 19744366266
virologic and serologic studies on infectious mononucleosis-like disease in children, with special reference to cytomegalovirus, epstein-barr virus and adenovirus infections. 19744366410
the presence of the epstein-barr viral genome in human lymphoblastoid b-cell lines and its absence in a myeloma cell line. 19744366935
the oncogenicity of epstein-barr virus. 19744366977
discussion of case-control study of hodgkin's disease. 19744366988
nasopharyngeal carcinoma: recent studies and outlook for a viral etiology. 19744366989
antibodies to herpes group viruses in patients with nasopharyngeal and other head and neck cancers. 19744366990
antibody levels to infectious agents other than epstein-barr virus in burkitt's lymphoma patients. 19744366991
immunological reactions to tumor-associated antigens in burkitts lymphoma and other lymphomas. 19744366992
epstein-barr virus dna in hodgkin's disease, american burkitt's lymphoma, and other human tumors. 19744366993
epstein-barr virus: one or a family of viruses. 19744366995
seroepidemiology of herpesvirus type epstein-barr in blood donors from communities around lyon. 19744367030
nasopharyngeal carcinoma: present status of knowledge. 19744367157
transformation of nonhuman primate lymphocytes by epstein-barr virus. 19744367158
superinfection with adenovirus of burkitt's lymphoma cell lines. 19744367238
animal model of human disease. burkitt's lymphoma, malignant lymphoma and lymphocytic leukemia. 19744367265
in vitro cellular immunity to epstein-barr virus in normal human subjects. 19744367339
attempts to detect virus-specific dna in human tumors. ii. nucleic acid hybridizations with complementary rna of human herpes group viruses. 19744367341
malaria antibody levels in patients with burkitt's lymphoma. 19744367834
epstein-barr virus-binding receptor on the surface of chronic lymphocytic leukaemic lymphocytes. 19744367999
[immunology of epstein-barr virus in lymphoproliferative diseases]. 19744368156
a health and seroepidemiological survey of a community in barbados. 19744368328
antibodies to epstein-barr and other viruses in children with acute lymphoblastic leukaemia. 19744368420
antibodies to epstein-barr virus, cytomegalovirus, and australia antigen in hodgkin's disease. 19744368421
detection of antibodies against virally-induced tumor-associated antigens by mixed hemadsorption. 19744368571
detection of tumor-virus associated antibodies by mixed hemadsorption. 19744368573
detection of epstein-barr virus (ebv)-associated nuclear antigen in human lymphoblastoid cell lines by means of an 125-i-igg-binding assay. 19744368574
editorial: burkitt's lymphoma;. 19744368606
epstein-barr virus and heterophile antibodies in infectious mononucleosis. 19744368690
epstein-barr virus specific diagnostic tests in infectious mononucleosis. 19744368691
evidence for a role of the epstein-barr virus in the etiology of human lymphoma. 19744368706
false negative and prozone reactions in tests for antibodies to epstein-barr virus-associated nuclear antigen. 19744368719
hematological and serological effects of rauscher leukemia virus and epstein-barr virus on immunosuppressed newborn subhuman primates. 19744368764
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