Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| structural characterization of as-mif and hjab1 during the inhibition of cell-cycle regulation. | the biological activities of macrophage migration inhibitory factor (mif) might be mediated through a classical receptor-mediated or non-classical endocytic pathway. jab1 (c-jun activation domain-binding protein-1) promotes the degradation of the tumor suppressor, p53, and the cyclin-dependent kinase inhibitor, p27. when mif and jab1 are bound to each other in various intracellular sites, mif inhibits the positive regulatory effects of jab1 on the activity of ap-1. the intestinal parasite, anisa ... | 2017 | 28366190 |
| molecular diagnosis of allergy to anisakis simplex and gymnorhynchus gigas fish parasites. | there has been an increase in the prevalence of hypersensitivity to anisakis simplex. there are fish parasites other than anisakis simplex whose allergenicity has not yet been studied. | 2017 | 28341528 |
| ige, igg1 and igg4 response to specific allergens in sensitized subjects showing different clinical reactivity to anisakis simplex. | background. anisakis simplex hypersensitive subjects may be sensitized without clinical allergy, or experience acute symptoms or chronic urticaria induced by raw fish. we studied whether the 3 subgroups differ in ige, igg1 or igg4 reactivity to specific anisakis simplex allergens. methods. 28 anisakis simplex-hypersensitive adults, 11 with acute symptoms, 9 with chronic urticaria, and 8 sensitized were studied. ige, igg1 and igg4 to rani s 1, 5, 9 and 10 were sought by elisa. ige and igg4 to nan ... | 2017 | 28294584 |
| determination of anti-anisakis simplex antibodies and relationship with αβ and γδ lymphocyte subpopulations in patients with crohn's disease. | the etiology of crohn's disease (cd) is still unknown although new theories are based on defects in innate immunity. we have previously shown a decrease in γδ t cells in cd patients. previous studies have shown a high prevalence of anti-a. simplex immunoglobulins in cd patients. the diminution of γδ t cells in the peripheral blood and intestinal mucosa of cd patients may create a state of immunosuppression that would facilitate a. simplex infection. | 2017 | 28168577 |
| population parameters and mito-nuclear mosaicism of anisakis spp. in the adriatic sea. | recombinant genotypes of a. simplex sensu stricto (s.s.) and a. pegreffii, two species of anisakis simplex complex found in sympatric waters of the mediterranean sea, are believed to be a product of interspecific hybridisation and/or dna introgression. in contrast, such events within an allopatric area as the adriatic sea are unlikely to occur and therefore observed recombination should be assessed more closely. we have genotyped 525 anisakids collected from migratory and non-migratory fish of t ... | 2017 | 28126544 |
| contracaecum osculatum and other anisakid nematodes in grey seals and cod in the baltic sea: molecular and ecological links. | populations of grey seals (halichoerus grypus), sprats (sprattus sprattus) and cod (gadus morhua) in the baltic sea are relatively stationary. the present work, applying classical and molecular helminthological techniques, documents that seals and cod also share a common parasite, the anisakid nematode contracaecum osculatum, which uses seals as the final host and fish as transport hosts. sequencing mitochondrial genes (cox1 and cox2) in adult worms from seals and third-stage larvae from livers ... | 2017 | 28124629 |
| detection of anisakid larvae in marinated mackerel sushi in tokyo, japan. | 2017 | 29279440 | |
| prevalence, molecular characterization, and clinical relevance of sensitization to anisakis simplex in children with sensitization and/or allergy to dermatophagoides pteronyssinus. | prevalence of the anisakis simplex's (as) sensitization in children sensitized to dermatophagoides pteronissynus (dp) is not known, neither it is to which percentage it might be due to cross-reactivity. the primary objective of the present retrospective cross-sectional study is to evaluate the prevalence of sensitization to as in children sensitized or allergic to dp. secondary outcomes were the prevalence of cross-reactivity and clinical relevance of the condition. the prevalence of sensitizati ... | 2017 | 29249135 |
| a multicenter study of ige sensitization to anisakis simplex and diet recommendation | allergy to anisakis simplex (s.) is spreading due to the increased consumption of raw, smoked or marinated fish. in humans, anisakis s. can directly attack the gastrointestinal mucosa, provoking a parasitosis known as anisakiasis, or giving rise to the formation of ige and, finally, inducing ige-mediated reactions like urticaria, angioedema and anaphylactic shock. during recent years, a dietary approach to anisakis s. infestation has also been addressed. | 2017 | 29189183 |
| modelling studies determing the mode of action of anthelmintics inhibiting in vitro trehalose-6-phosphate phosphatase (tpp) of anisakis simplex s.l. | the trehalose-6-phosphate phosphatase (tpp) enzyme is involved in the synthesis of trehalose, the main sugar in the energy metabolism of nematodes. tpp is a member of the had-like hydrolase superfamily and shows a robust and specific phosphatase activity for the substrate trehalose-6-phosphate. the presence of conserved active sites of tpp in closely related nematodes and its absence in humans makes it a promising target for antiparasitic drugs. in the present study, homology modeling, molecular ... | 2017 | 29170085 |
| a combined human case of dirofilaria ursi infection in dorsal subcutaneous tissue and anisakis simplex sensu stricto (s.s.) infection in ventral subcutaneous tissue. | dirofilaria ursi is a filarial nematode that parasitizes the subcutaneous tissues of the american black bear (ursus americanus) and japanese black bear (ursus thiabetanus japonicus). d. ursi that has parasitized black bears has the potential to subsequently infect humans. in addition, extra-gastrointestinal anisakiasis is less common in japan. | 2017 | 29118653 |
| human gastric hyperinfection by anisakis simplex: a severe and unusual presentation and a brief review. | anisakiasis is an emerging marine food-borne zoonosis resulting from the accidental ingestion of anisakis larvae, through the consumption of raw or undercooked infected seafood products. the first case of human gastric hyperinfection by anisakis simplex with an unusual and severe presentation, occurring in a portuguese woman, is described in this article. over 140 anisakid larvae were removed by gastroscopy. massive infection is uncommon in areas where the consumption of raw fish is not part of ... | 2017 | 28882665 |
| allergenic activity of pseudoterranova decipiens (nematoda: anisakidae) in balb/c mice. | anisakis simplex is the only fishery-product associated parasite causing clinical allergic responses in humans so far. however, other anisakids, due to the presence of shared or own allergens, could also lead to allergic reactions after sensitization. the aim of this study was to determine if pseudoterranova decipiens belonging to the family anisakidae has allergenic activity and is able to induce sensitization after oral administration in a murine (balb/c mice) model. | 2017 | 28606183 |
| anisakis haemoglobin is a main antigen inducing strong and prolonged immunoreactions in rats. | anisakis simplex larvae are well known to cause gastrointestinal and allergic manifestations after ingestion of parasitized raw or undercooked seafood. the antibody recognition dynamics against the components of anisakis larval antigen after primary and re-infection with anisakis live larvae remain unclear. for this study, immunoblot analyses of serum igg, ige, and igm against anisakis larval somatic extract were performed in rats that had been orally inoculated with a. simplex live larvae. mult ... | 2017 | 28497226 |
| a case of small intestinal intussusception caused by anisakiasis diagnosed and treated by upper gastrointestinal endoscopy. | a 35-year-old man attended our hospital with complaining of epigastric pain and vomiting. he was diagnosed with bowel intussusception based on the target sign revealed in the upper jejunum by abdominal computed tomography. however, the cause of the intussusception was not clear. insertion of an endoscope into the jejunum revealed prominent edema in the upper part of the jejunum, and anisakis simplex was identified at the site and removed. symptoms rapidly improved after endoscopic treatment. we ... | 2017 | 28781357 |
| excretory/secretory products of anisakid nematodes: biological and pathological roles. | parasites from the family anisakidae are widely distributed in marine fish populations worldwide and mainly nematodes of the three genera anisakis, pseudoterranova and contracaecum have attracted attention due to their pathogenicity in humans. their life cycles include invertebrates and fish as intermediate or transport hosts and mammals or birds as final hosts. human consumption of raw or underprocessed seafood containing third stage larvae of anisakid parasites may elicit a gastrointestinal di ... | 2017 | 28645306 |
| atrial fibrillation in anaphylaxis. | the relationship between anaphylaxis and cardiovascular events has been reported in the past. while skin and respiratory symptoms are usually the most common and the first to appear, cardiovascular complications play a key role and represent the leading cause of death in anaphylaxis. | 2017 | 28601540 |
| anisakis sensitivity in italian children: a prospective study. | 2017 | 28398206 | |
| tissue-specific transcriptomes of anisakis simplex (sensu stricto) and anisakis pegreffii reveal potential molecular mechanisms involved in pathogenicity. | larval stages of the sibling species of parasitic nematodes anisakis simplex (sensu stricto) (s.s.) (as) and anisakis pegreffii (ap) are responsible for a fish-borne zoonosis, known as anisakiasis, that humans aquire via the ingestion of raw or undercooked infected fish or fish-based products. these two species differ in geographical distribution, genetic background and peculiar traits involved in pathogenicity. however, thus far little is known of key molecules potentially involved in host-para ... | 2018 | 29321072 |
| anisakis spp. larvae in different kinds of ready to eat products made of anchovies (engraulis encrasicolus) sold in italian supermarkets. | in this study the occurrence of visible anisakid larvae in semi-preserved anchovy products sold on the italian market was investigated. totally, 107 ready to eat products (33 salted-ripened, 49 in oil and 25 marinated) were sampled. each sample was digested, then the digested material was observed under natural and uv light. parasites were counted, collected and microscopically identified to genus level. a representative subset was molecularly identified using the cox2 gene. at least one visible ... | 2018 | 29306733 |
| metazoan parasite fauna of migrating common garfish, belone belone (l.), in the baltic sea. | a total of 35 common garfish, belone belone (linnaeus, 1761), were studied for metazoan parasites on their spawning grounds in the western baltic sea. nine parasite species were found, and six new locality records could be established for german coastal waters (axine belones, monogenea; proteocephalus sp., cestoda; anisakis simplex (s.s.), contracaecum rudolphii a and hysterothylacium aduncum, nematoda; echinorhynchus gadi, acanthocephala). for the first time, the marine ectoparasite a. belones ... | 2018 | 29351069 |