Publications

uterus didelphys and pregnancy: an unusual case in an 18-year-old patient.	an unusual case of a full-term pregnancy in a patient with a uterus didelphys is presented. the main complication was the formation of pyocolpos in a blind hypoplastic hemivagina observed early in gestation. the therapeutic approach and the related problems are discussed.	2006	1563657
external cephalic version and daily post-versional maternal self-assessment of fetal presentation. a prospective study.	external cephalic version (ecv) using tocolysis is a widely recognized low-risk intervention in cases of breech presentation, particularly in areas where resources are scarce and the perinatal mortality is high in vaginal breech deliveries. in such a setting, pregnant women were trained to make regular self-assessments of the presenting fetal part after ecv in order to detect spontaneous reversions to breech presentation. it was found that such maternal involvement could significantly improve th ...	2006	1563651
duration of immunity after tetanus vaccination.		2006	4125629
[liver and splenic ruptures as a complication of heart pressure massage].	injuries of the abdominal organs, especially liver and spleen, which were caused by resuscitative measures, can occasionally raise problems if an expert opinion on death is obtained particularly with regard to previous traumatization and if the question arises whether the trauma could have been avoided or not. these questions will be discussed from different points of view by means of ten cases.	2006	1489324
sensationalism or sensitivity: use of words in stories on acquired immune deficiency syndrome (aids) by associated press videotext.	although it appeared initially reluctant to cover the story at all, the mainstream press in the united states has supplied almost daily reports on aids since the mid-1980s. the author examined four weeks of stories on the associated press videotext service in early 1986 in an effort to evaluate the validity of critics' charges that journalists were over-emphasizing the role of homosexuals in the progress of the disease, and that their stories were laden with negative or sensationalistic terms. t ...	2006	1856471
anticipation in obstetrical care. proceedings of the postgraduate course in reproductive medicine. amsterdam, june 7-8, 1990.		2006	1809603
antigen-receptor complex stimulation triggers protein kinase c-dependent cd11a/cd18-cytoskeleton association in t lymphocytes.	although it is well accepted that intercellular adhesion involving the cd11a/cd18 (lfa-1) complex is critical in a wide array of t cell-dependent processes, recent demonstrations of an lfa-1 high avidity state, induced by triggering the t cell receptor (tcr) complex, has raised questions about the intracellular signals generated and molecular events leading to effective cell coupling, as well as their orderly sequence. in this study, we assessed the effects of t cell activation on the actin-base ...	2006	1346786
female-attracting property of urinary compounds in male mice. stereospecificity and interaction with other factors.		2007	2074900
cervical arterial dissection following trauma.		2007	1892576
[quinidine-induced photoallergy. a clinical and experimental study].	photoallergies are type-iv allergic reactions of a special kind. photoallergies due to quinidine sulphate were described as early as 1942. we present a case of quinidine sulphate-induced photodermatitis. the photoallergic reaction to quinidine sulphate was reproducible not only after oral intake but also in the photopatch test. in addition, an eczematous dermatitis was provoked after intradermal injection of quinidine sulphate previously exposed to uv-a irradiation in vitro together with serum t ...	2007	1829069
aerosol application of interferon-alpha in the treatment of bronchioloalveolar carcinoma.	10 patients with locally advanced bronchioloalveolar carcinoma were treated with interferon-alpha as an inhaled aerosol. initial doses ranged between 1 and 10 mu daily or thrice weekly and were then increased to 20 mu daily. treatment was continued until disease progression or excessive toxicity occurred, 9 patients were evaluable for toxicity. in 1 case treatment had to be stopped after 2 weeks due to fever, fatigue and progressive dyspnoea. 2 patients developed fever, 1 had malaise, fatigue an ...	2007	2168195
comparison of the effects of atenolol and nifedipine on glucose, insulin, and lipid metabolism in patients with hypertension.	various aspects of carbohydrate and lipid metabolism have been studied in two groups of patients with mild hypertension before and after four months of treatment with either nifedipine (n = 12) or atenolol (n = 12). mean (+/- sem) blood pressure fell to the same degree following treatment with either nifedipine (147 +/- 3/98 +/- 2 to 134 +/- 2/85 +/- 2 mm hg) or atenolol (149 +/- 3/99 +/- 2 to 135 +/- 2/86 +/- 3 mm hg). circulating plasma glucose, insulin, and triglyceride concentrations were me ...	2007	2043298
time to adoption of an innovation by dentists in private practice: sealant utilization.	dentists can be divided into five adoption categories based upon their time of adoption of pit and fissure sealants: innovators, early adopters, early majority, late majority, and laggards. the differences among dentists in the five adoption categories were examined for four classes of variables: practice characteristics, dentist characteristics, communication of information, and practice environment. questionnaires were mailed in september 1984 to a random sample (n = 521) of washington state d ...	2007	1920266
admissions to mental handicap hospitals.		2007	1932957
magnetic resonance imaging in idiopathic hypopituitarism.		2007	1954969
dissection of the prostatic apex for radical cystectomy and detubed ileocystoplasty.		2007	2780674
guy's sets nhs trust standard.		2007	1945114
insulin secretagogues induce ca(2+)-like changes in cytoplasmic mg2+ in pancreatic beta-cells.	the effects of insulin secretagogues on the cytoplasmic mg2+ concentration ([mg2+]i) of pancreatic beta-cells were studied in suspensions and in individual beta-cells using dual-wavelength fluorometry and the indicator mag-fura-2. average [mg2+]i was in the 800-900 microm range in a medium containing 3 mm glucose. when the sugar concentration was raised to 20 mm, the cells reacted with an initial lowering of [mg2+]i followed by an increase. the sugar apparently also stimulated leakage of the mg2 ...	2007	2223873
insulin secretagogues induce ca(2+)-like changes in cytoplasmic mg2+ in pancreatic beta-cells.	the effects of insulin secretagogues on the cytoplasmic mg2+ concentration ([mg2+]i) of pancreatic beta-cells were studied in suspensions and in individual beta-cells using dual-wavelength fluorometry and the indicator mag-fura-2. average [mg2+]i was in the 800-900 microm range in a medium containing 3 mm glucose. when the sugar concentration was raised to 20 mm, the cells reacted with an initial lowering of [mg2+]i followed by an increase. the sugar apparently also stimulated leakage of the mg2 ...	2007	2223873
[delirious and hallucinatory disorders in late psychoses with the pattern of "home paranoia"].	paranoid and hallucination syndromes were studied in 71 cases of senile non-dementia psychoses located at the patients' house. two major variants were singled out: paranoid and hallucinatory (the latter subdivided into patterns with or without the persecution delusion, and physical affection delusion). paranoid variant was shown to be based upon a special transformation of visual perception with formation of delusions of penetration of a "stranger" into the patients' home. hallucinatory variants ...	2007	2176045
flumazenil therapy in benzodiazepine self-poisoning.		2007	2045270
cd4(+) t lymphocytes mediate colitis in hla-b27 transgenic rats monoassociated with nonpathogenic bacteroides vulgatus.	hla-b27/beta2 microglobulin transgenic (tg) rats develop spontaneous colitis when raised under specific pathogen-free (spf) conditions or after mono-association with bacteroides vulgatus (b. vulgatus), whereas germ-free tg rats fail to develop intestinal inflammation. spf hla-b27 tg rnu/rnu rats, which are congenitally athymic, remain disease free. these results indicate that commensal intestinal bacteria and t cells are both pivotal for the development of colitis in tg rats. however, it is not ...	2007	17206701
therapeutic effects of roxithromycin in interleukin-10-deficient colitis.	a limited number of therapeutic strategies are currently available to treat patients with inflammatory bowel disease (ibd). interleukin-10 (il-10)-deficient mice, well characterized as an experimental model of ibd, develop severe chronic colitis because of aberrant th1 responses. roxithromycin (rxm), a macrolide antibiotic, has received attention because it offers not only antibacterial but also immunosuppressive effects. we examined the immunosuppressive effect of rxm on the development of ibd.	2007	17245768
epithelial barrier disruption allows nondisease-causing bacteria to initiate and sustain ibd in the il-10 gene-deficient mouse.	in the il-10 gene-deficient mouse model, development of intestinal inflammation is associated with a defect in epithelial barrier integrity that is thought to allow sufficient passage of bacteria or bacterial antigens to initiate a mucosal immune response. microbial monoassociation experiments into axenic animals have shown that some, but not all, endogenous bacteria will initiate an intestinal inflammatory response. for instance, bacteroides vulgatus does not initiate intestinal inflammation in ...	2007	17427241
reduced mucosal antimicrobial activity in crohn's disease of the colon.	in order to maintain the mucosal barrier against luminal microorganisms the intestinal epithelial cells synthesise various broad-spectrum antimicrobial peptides including defensins and cathelicidins. recent studies indicate that both may be deficient in crohn's disease. to elucidate the possible functional consequences of this deficiency antimicrobial activity in colonic mucosa from patients with inflammatory bowel disease and healthy controls was investigated.	2007	17456510
identification of commensal bacterial strains that modulate yersinia enterocolitica and dextran sodium sulfate-induced inflammatory responses: implications for the development of probiotics.	an increasing body of evidence suggests that probiotic bacteria are effective in the treatment of enteric infections, although the molecular basis of this activity remains elusive. to identify putative probiotics, we tested commensal bacteria in terms of their toxicity, invasiveness, inhibition of yersinia-induced inflammation in vitro and in vivo, and modulation of dextran sodium sulfate (dss)-induced colitis in mice. the commensal bacteria escherichia coli, bifidobacterium adolescentis, bacter ...	2007	17485456
evolution of symbiotic bacteria in the distal human intestine.	the adult human intestine contains trillions of bacteria, representing hundreds of species and thousands of subspecies. little is known about the selective pressures that have shaped and are shaping this community's component species, which are dominated by members of the bacteroidetes and firmicutes divisions. to examine how the intestinal environment affects microbial genome evolution, we have sequenced the genomes of two members of the normal distal human gut microbiota, bacteroides vulgatus ...	2007	17579514
bacteroides sp. strain d8, the first cholesterol-reducing bacterium isolated from human feces.	the microbial community in the human colon contains bacteria that reduce cholesterol to coprostanol, but the species responsible for this conversion are still unknown. we describe here the first isolation and characterization of a cholesterol-reducing bacterium of human intestinal origin. strain d8 was isolated from a 10(-8) dilution of a fresh stool sample provided by a senior male volunteer with a high capacity to reduce luminal cholesterol to coprostanol. cholesterol-to-coprostanol conversion ...	2007	17616613
dual-association of gnotobiotic il-10-/- mice with 2 nonpathogenic commensal bacteria induces aggressive pancolitis.	monoassociating gnotobiotic il-10-deficient (-/-) mice with either nonpathogenic enterococcus faecalis or a nonpathogenic escherichia coli strain induces t-cell-mediated colitis with different kinetics and anatomical location (e. faecalis: late onset, distal colonic; e. coli: early onset, cecal). hypothesis: e. faecalis and e. coli act in an additive manner to induce more aggressive colitis than disease induced by each bacterial species independently.	2007	17763473
effects of t's and blues abuse on pregnancy outcome and infant health status.	t's and blues (pentazocine and tripelennamine) abuse during pregnancy has been reported to be associated with adverse maternal and fetal effects. in this study, conducted at parkland memorial hospital in dallas, texas, pregnancy outcome and health status of infants born to 23 t's and blues abusers were compared to a group of 100 unexposed women and their infants. infants born to t's and blues abusers had significantly reduced birthweight, length, head circumference, and an increased frequency of ...	2007	2222629
single-dose pharmacokinetics of 14c-lovastatin in chronic renal failure.	an open study on the pharmacokinetics of lovastatin was conducted in six patients with chronic renal failure (mean creatinine clearance, 0.40 ml/sec; range, 0.20 to 0.65 ml/sec) and seven healthy subjects. plasma levels of 3-hydroxy-3-methylglutaryl-coenzyme reductase inhibitory activity (total and active) and total radioactivity were determined over 168 hours after a single dose of 80 mg 14c-lovastatin. the mean area under the plasma concentration-time curve for active inhibitors were 606 +/- 3 ...	2007	1914380
investigation and treatment of a multiple limb birth.	we report a baby born with three fully developed normally functioning legs. the third leg was attached to the baby's sacrum via an iliac bone at the site of a spina bifida. a primitive perineum was present. innervation of the limb was via a sacral hiatus with a myelomeningocele. a rudimentary peritoneal sac was found at operation containing a blind loop of bowel suspended by a mesentery. the additional leg was found to have no cortical representation using somatic evoked potentials although lumb ...	2007	1892571
decompression surgery in graves' orbitopathy--a review of 14 years' experience at the orbita centrum, amsterdam.		2008	2687051
induction of dependence on hematopoietic proteins for viability and receptor upregulation in differentiating myeloid leukemic cells.	there are different types of myeloid leukemic cells that can be induced to differentiate to mature granulocytes or macrophages by different hematopoietic regulatory proteins. one type of leukemic clone can be induced to differentiate by recombinant macrophage and granulocyte differentiation-inducing protein-type 2 (mgi-2), which we have shown is interleukin-6 (il-6), and another type of leukemic clone can be differentiated by recombinant granulocyte-macrophage colony-stimulating factor (gm-csf) ...	2008	2546628
[questions and answers on urological care. management of a balloon catheter which cannot be removed smoothly].		2008	2630750
bioactivation of selenocysteine derivatives by beta-lyases present in common gastrointestinal bacterial species.	studies in cell cultures and animal models have demonstrated cancer chemopreventive effects of certain selenium compounds. here we describe the screening of cysteine s-conjugate beta-lyase activity in bacterial species that are implicated in the bio-activation of sulfur- and selenocysteine derivatives. we screened a range of bacterial species commonly found in the human intestine for beta-lyase activity on se-p-methoxybenzylselenocysteine and the natural occurring s-methylcysteine and se-methyls ...	2008	19326339
neurocristopathy syndrome: review of four cases.	aberrant embryologic development of the neural crest may clinically result in one of several patterns of malformation. four examples of the neurocristopathy syndrome are described that collectively feature a very broad range of expression in these infants. because of the many expressions, the syndrome may not be recognized. we believe that greater familiarity with the disorder will aid in the discovery of unsuspected anomalies and provide clues about predisposing etiologies.	2008	2359735
gut microbes in crohn's disease: getting to know you better?	biomarkers in inflammatory bowel disease (ibd) are needed to help in disease diagnosis, prognosis, and assessment of disease activity. the best serologic markers to date measure antibody responses to normal commensal flora. these antibody responses can provide prognostic information as well as clues to disease pathogenesis. there remains room for additional biomarkers to clarify the diagnosis for certain patients with indeterminate colitis or small bowel crohn's disease (cd) with protean manifes ...	2008	18289202
effects of rosa rugosa petals on intestinal bacteria.	the effects of pulverized petal of rosa rugosa on the growth of 10 species of intestinal and pathogenic bacteria were investigated. growth of bifidobacteria and lactobacilli was not affected by the addition of the petal in plate cultivation. however, the growth of bacteroides vulgatus, escherichia coli, staphylococcus aureus, and bacillus cereus was completely inhibited by the addition of 0.1, 0.5, 0.1, and 0.05% (w/v) of the petal respectively. in liquid cultivation, the addition of the petal ( ...	2008	18323655
detection of possible ai-2-mediated quorum sensing system in commensal intestinal bacteria.	the vibrio harveyi strain bb170-autoinducer bioassay was used to detect possible quorum sensing autoinducer-2 molecule (ai-2) in culture fluids of commensal intestinal bacteria. culture fluids of bacteroides vulgatus, clostridium proteoclasticum, escherichia coli, eubacterium rectale, lachnospira multipara, pseudobutyrivibrio ruminis, roseburia intestinalis, ruminococcus albus and ruminococcus flavefaciens contained ai-2-like molecules. the pcr bands from some of the tested strains could be also ...	2008	18661296
[analysis of the nursing factors responsible for expanding the sphere of daily activities of patients with parkinson's disease].		2008	2612141
[analysis of the nursing factors responsible for expanding the sphere of daily activities of patients with parkinson's disease].		2008	2612141
impact of troop dental health on combat readiness.		2008	3108716
[foreign bodies of the digestive tract].		2008	2259119
fifty hours for the poor?		2008	2612144
fifty hours for the poor?		2008	2612144
cardiac hypersensitivity to 5-aminosalicylic acid.		2008	2566070
the role of transplantation in liver disease.	liver transplantation is rapidly emerging as the most effective treatment pathway for a growing number of acute and chronic liver disease states. indications and contraindications to transplant are undergoing continuous revision and clarification as experience is accrued in the expanding number of treatment centers. for some disorders such as primary biliary cirrhosis, sclerosing cholangitis, and chronic active hepatitis with cirrhosis, the role of transplantation in patient management is obviou ...	2008	2648619
uptake of presymptomatic predictive testing for huntington's disease.	predictive testing by means of gene probes was offered to 110 adults at risk of huntington's disease (hd). a further 91 individuals spontaneously sought predictive testing. acceptance rates were highest (85.1%) amongst 47 individuals who spontaneously sought testing and were referred from outside the region, and lowest (15.5%) among the 110 invited to consider predictive testing. many expressed an interest in predictive testing, then withdrew. fetal exclusion testing was rarely requested, and th ...	2008	2570293
[how healthy are germans?].		2008	2398772
infective endocarditis in children. a seven-year experience.	eighteen children with infective endocarditis were detected over seven years. fever, gastrointestinal and chest symptoms were striking features. anaemia, elevated leukocyte count and sedimentation rate were constant laboratory findings. strep. viridans and staph. aureus were the commonest organisms isolated. we concluded that rheumatic and congenital heart disease are equally important in predisposition to infective endocarditis.	2008	2519331
an unusual cause of abdominal pain.		2008	2268772
mechanics of the lung and chest wall.		2008	2291386
[percutaneous drainage of fistula-associated abscesses and biliary fistulas].	33 abdominal abscesses associated with fistulae in 31 patients were treated by percutaneous drainage. 19 of these patients had had surgery immediately preceding the drainage. in 64% the percutaneous drainage led to a diagnosis of an internal fistula. additional therapeutic measures, because of the fistula, were necessary in 45% (operation, biliary drainage, repositioning of catheter). the average duration of drainage was 29 days. 77% of those abscesses which could be drained were treated success ...	2008	2538887
structural and functional aspects of the receptors for platelet-derived growth factor.	platelet-derived growth factor (pdgf) is a 30 kda dimer of disulfide-bonded a and b chains. three isoforms of pdgf have been isolated (pdgf-aa, pdgf-ab and pdgf-bb). these bind with different affinities and specificities to two structurally related cell surface receptors, viz. the alpha-receptor and the beta-receptor. the receptors are transmembrane proteins with an intracellular, ligand-stimulatable protein tyrosine kinase domain. activation of the receptors is intimately associated with recept ...	2008	2562360
[shoulder joint arthroplasty--joint replacement].		2008	2576713
closed intramedullary nailing of diaphyseal fractures of the femur. problems related to anatomical variations of the greater trochanter.	an examination of the radiographs of 100 normal femurs revealed an anatomical variation consisting of lateralization of the trochanteric mass in relation to the femoral diaphysis. this involves disalignment of the apex of the greater trochanter in relation to the medullary canal, with consequent complications during closed intramedullary nailing such as varus of the fracture segments, valgus of the nail, fracture of the medial cortex. since becoming aware of this anatomical variation and its pos ...	2009	2737894
[digital subtraction angiography of acquired arteriovenous fistulas of the extremities].	the signs of arterio-venous fistulae in the extremities have been evaluated by dsa in 20 patients. angiographic signs for the presence of a-v fistulae are the following findings: dilatation of the supplying artery, elongation of the supplying artery, solitary a-v aneurysm, angiomatous a-v aneurysm, reduced blood flow distal to the a-v fistula, early venous filling, development of a venous collateral circulation and demonstration of retrograde venous flow. angiography remains the method of choice ...	2009	2836906
dose-response relationships regarding vitamin b-6 in elderly people: a nationwide nutritional survey (dutch nutritional surveillance system).	the dietary intake and biochemical status of vitamin b-6 in 476 apparently healthy dutch elderly people (aged 65-79 y), who were not using drugs known to affect vitamin b-6 metabolism, were evaluated. intake of vitamin b-6 per gram protein was related to biochemical data, namely plasma pyridoxal 5'-phosphate (plp) and cofactor stimulation of aspartate aminotransferase in erythrocytes (ast-ac). based on a cutoff point of 2.02 for ast-ac, approximately 9% of the elderly people not using vitamin b- ...	2009	2756926
sluggish schizophrenia in the modern classification of mental illness.	the concept of latent schizophrenia was developed by e. bleuler (1911) and was further promoted in the studies of a number of research psychiatric schools of europe, the united states, japan, and other countries. in soviet psychiatry, there is a long-established tradition of studying "soft" forms of schizophrenia (kerbikov 1933; rozenshtein 1933; brukhanskii 1934). in the systematics of schizophrenia, developed by snezhnevsky (1969) and his colleagues, sluggish schizophrenia is viewed not as an ...	2009	2696084
[ultrasonographic evaluation of hepatic hematoma after biopsy].		2009	2690789
time-resolved fluorescence immunoassay system especially suited for research applications.		2009	2920419
cancer of colon and rectum.		2009	2686902
when to use posts.		2009	2698331
clinical studies of polymyalgia rheumatica. a proposal of diagnostic criteria.	a differential diagnosis of polymyalgia rheumatica (pmr) and rheumatoid arthritis (ra) can be difficult in elderly patients, especially at the prodromal phase of ra. furthermore, it was felt that there might be a diagnostic criteria for pmr specific to the japanese. accordingly, we have retrospectively studied the pmr patients who had come to our hospital, for making a diagnostic criteria. we especially stressed the distinguishing of pmr from ra in elderly patients. the criteria proposed are as ...	2009	2681899
effect of free cholesterol on incorporation of triolein in phospholipid bilayers.	triacylglycerols are the major substrates for lipolytic enzymes that act at the surface of emulsion-like particles such as triglyceride-rich lipoproteins, chylomicrons, and intracellular lipid droplets. this study examines the effect of cholesterol on the solubility of a triacylglycerol, triolein, in phospholipid surfaces. solubilities of [carbonyl-13c]triolein in phospholipid bilayer vesicles containing between 0 and 50 mol % free cholesterol, prepared by cosonication, were measured by 13c nmr. ...	2009	3676293
otospongiosis and sodium fluoride. a clinical double-blind, placebo-controlled study on sodium fluoride treatment in otospongiosis.	the effect of sodium fluoride treatment in patients with otospongiosis has been evaluated in a prospective clinical double-blind, placebo-controlled study of 95 patients. the results showed a statistically significant greater deterioration of hearing loss in the placebo group than in the group actively treated with 40 mg of sodium fluoride daily. these results support the view that sodium fluoride can change otospongiotic, active lesions to more dense, inactive otosclerotic lesions.	2009	2655462
clinical aspects of liver atrophy.	the implications of selective liver atrophy in the management of hepatobiliary disease have only recently been recognised and discussed. this editorial focuses on clinical aspects of liver atrophy together with some relevant experimental data.	2009	2646358
rural nursing: developing the theory base.	many health care needs of rural dwellers cannot be adequately met through the use of existing nursing models alone but require unique approaches emphasizing the special needs of this population. the development of an integrated theory base for rural nursing is necessary. a retroductive approach, building upon both qualitative and quantitative research data, is being used to develop a theory of rural nursing. key concepts identified are: work beliefs and health beliefs; isolation and distance; se ...	2009	2772454
the acid-etch retained rest for removable partial dentures.	this article will describe the techniques for composite and metal rests. it will also discuss a clinical follow-up of 18 patients who have had metal or composite rests in place from three to 18 months.	2009	2691082
a century of change in neurosurgery at johns hopkins: 1889-1989.	neurosurgical admissions to the johns hopkins hospital during the first year of its existence, the first and last years of harvey cushing's practice, the last years of walter dandy's practice, the last years of earl walker's tenure, and the current neurosurgical case load are reviewed. sixteen patients with neurosurgical problems were admitted during the first year of the hospital's existence. in the first year of harvey cushing's staff appointment, 38 neurosurgical patients were admitted. infec ...	2009	2681565
u.s./japan cooperative cancer research program. proceedings of the united states-japan melanoma and skin cancer seminar on the biology and comparative features. november 13-15, 1987, tokyo.		2009	2715649
[functional paraganglioma (pheochromocytoma) in an aortico-pulmonary location].		2009	2815638
subaortic stenosis associated with anomalous right ventricular muscle bundle and ventricular septal defect.	a rare case of biventricular outflow tract obstruction in the form of discrete subaortic membrane and hypertrophic anomalous right ventricular muscle bundle associated with ventricular septal defect is presented.	2009	2777307
[total parenteral nutrition in surgical patients. our experience].		2009	3108726
differential diagnosis of patients with abnormal serum creatine kinase isoenzymes.	for the diagnosis of myocardial injury, particularly ami, ck-mb has become the gold standard. changing ck-mb activities in serially collected blood from patients with suggestive signs and symptoms of ami is almost pathognomonic for infarction. nevertheless, an increased ck-mb cannot be equated with ami owing to the many other types of inflammatory, traumatic, and miscellaneous forms of injury to the heart and the trace activities of ck-mb in skeletal muscle. other enzyme tests for ami are less e ...	2009	2686905
detection and persistence of fecal bacteroidales as water quality indicators in unchlorinated drinking water.	the results of this study support the use of fecal bacteroidales qpcr as a rapid method to complement traditional, culture-dependent, water quality indicators in systems where drinking water is supplied without chlorination or other forms of disinfection. a sybr-green based, quantitative pcr assay was developed to determine the concentration of fecal bacteroidales 16s rrna gene copies. the persistence of a bacteroides vulgatus pure culture and fecal bacteroidales from a wastewater inoculum was d ...	2009	19261420
commensal bacteria can enter colonic epithelial cells and induce proinflammatory cytokine secretion: a possible pathogenic mechanism of ulcerative colitis.	interleukin 2 (il-2)- and il-10-knockout mice develop spontaneous colitis under conventional but not germ-free conditions, suggesting that commensal bacteria play an important role in the pathogenesis of colitis. however, interactions between commensal bacteria and colonic epithelial cells have not been fully investigated. we therefore assessed the ability of various commensal bacteria and probiotics to adhere to and invade colonic epithelial cells. effects of the bacteria on production of proin ...	2009	19369513
pattern extraction of structural responses of gut microbiota to rotavirus infection via multivariate statistical analysis of clone library data.	this study developed a new statistical strategy for analyzing clone library data to observe whether there is a defined pattern in structural responses of gut microbiota to environmental perturbations. a large clone library of genus bacteroides was constructed with fecal samples for each subject in rotavirus-infected (group r) and healthy children (group h). in all, 665 clones of the 12 group h subjects and 284 clones of the nine group r subjects were sequenced and classified into 34 operational ...	2009	19453743
modulation of the intestinal microbiota alters colitis-associated colorectal cancer susceptibility.	it is well established that the intestinal microbiota plays a key role in the pathogenesis of crohn's disease (cd) and ulcerative colitis (uc) collectively referred to as inflammatory bowel disease (ibd). epidemiological studies have provided strong evidence that ibd patients bear increased risk for the development of colorectal cancer (crc). however, the impact of the microbiota on the development of colitis-associated cancer (cac) remains largely unknown. in this study, we established a new mo ...	2009	19551144
transepithelial activation of human leukocytes by probiotics and commensal bacteria: role of enterobacteriaceae-type endotoxin.	the goal of the current study was to clarify whether commercially available probiotics induce greater trans-epithelial activation of human leukocytes than do commensal, food-derived and pathogenic bacteria and to identify the compounds responsible for this activation. eleven different bacterial strains, and some of their pathogen-associated molecular patterns, were incubated apically on a confluent layer of intestinal epithelial cells (caco-2), which were basolaterally co-cultured with human mon ...	2009	19714861
the frequency of alcoholism and alcohol related brain disorders in various regions of oslo city. an autopsy study.	the autopsy materials from the 5-year period 1983-1987 from ullevål and aker hospitals in oslo were reviewed. all cases with alcoholism were recorded and the histological sections were re-examined with regard to the presence of wernicke's encephalopathy and alcoholic cerebellar atrophy. the two materials were compared statistically in order to see whether any difference in the frequency of alcoholism and alcohol related brain disorders could be demonstrated between the geographic areas served by ...	2009	2760752
craniofacial trauma.	the treatment of combined major dislocations of the face and skull requires a craniofacial team consisting of a plastic maxillofacial surgeon, a neurosurgeon, an anesthesiologist, and radiologists. the best results can only be achieved at the primary intervention both from a functional and an esthetic standpoint. careful preoperative clinical and radiologic examinations are mandatory to reach these high goals. in primary repair, the cranial approach aims at constructing "a monobloc bone flap" to ...	2009	2672614
dexamethasone suppression test nonsuppression and tardive dyskinesia.		2009	2763856
post-translational processing of anglerfish islet somatostatin precursors.	two distinct somatostatin precursors are synthesized in anglerfish (af) islets. in addition to a precursor which has somatostatin 14 (ss-14) as a c-terminal cleavage product, a precursor which contains at its c-terminus [tyr7, gly10] ss-14 as a potential cleavage product is also synthesized. however, even though an arg-lys pair is located immediately n-terminal to ala1 of the c-terminal tetradecapeptide, [tyr7, gly10]ss-14 was not found in significant amounts in extracts of af islets. instead, a ...	2010	2863927
foot and ankle injuries in theatrical dancers.	the theatrical dancer is a unique combination of athlete and artist. the physical demands of dance class, rehearsal, and performance can lead to injury, particularly to the foot and ankle. ankle sprains are the most common acute injury. chronic injuries predominate and relate primarily to the repeated impact loading of the foot and ankle on the dance floor. contributing factors include anatomic variation, improper technique, and fatigue. early and aggressive conservative management is usually su ...	2010	2866150
nonpalpable testes in young boys: evaluation with mr imaging.	a prospective evaluation of magnetic resonance (mr) imaging for localization of a nonpalpable testis was performed in 24 boys aged 11 months to 6 years. definitive surgical follow-up was obtained for 15 nonpalpable testes in 14 patients who form the basis of this study. mr imaging correctly indicated the unilateral absence of a testis in six of seven patients prospectively and all seven patients retrospectively. surgically localized undescended testes were identified with mr imaging in five of e ...	2010	2902656
lessons learned from the anaerobe survey: historical perspective and review of the most recent data (2005-2007).	the rationale and lessons learned through the evolution of the national survey for the susceptibility of bacteroides fragilis group from its initiation in 1981 through 2007 are reviewed here. the survey was conceived in 1980 to track emerging antimicrobial resistance in bacteroides species.	2010	20067390
molecular characterisation of the faecal microbiota in patients with type ii diabetes.	the investigation provides molecular analyses of the faecal microbiota in type 2 diabetic patients. in order to characterise the gut microbiota in diabetic patients and to assess whether there are changes in the diversity and similarity of gut microbiota in diabetic patients when compared with healthy individuals, bacterial dnas from 16 type 2 diabetic patients and 12 healthy individuals were extracted from faecal samples and characterised by pcr-denaturing gradient gel electrophoresis (dgge) wi ...	2010	20087741
identification of clinically important anaerobic bacteria by an oligonucleotide array.	anaerobic bacteria can cause a wide variety of infections, and some of these infections can be serious. conventional identification methods based on biochemical tests are often lengthy and can produce inconclusive results. an oligonucleotide array based on the 16s-23s rrna intergenic spacer (its) sequences was developed to identify 28 species of anaerobic bacteria and veillonella. the method consisted of pcr amplification of the its regions with universal primers, followed by hybridization of th ...	2010	20129959
isolation of bacteria from mouse caecal samples and description of bacteroides sartorii sp. nov.	caecal samples from wild-type and tnf(deltaare) mice were cultured on selective media containing bile salts, amino acids or casein macro-peptides. twenty-two strains were isolated and identified by 16s rrna gene sequencing. twenty-one strains showed >98% similarity to known bacteria (blautia spp., clostridium innocuum, enterococcus spp., escherichia coli, lactobacillus murinus, parabacteroides goldsteinii and shigella dysenteriae). one additional isolate, strain a-c2-0, was a new bacterium. the ...	2010	20369227
consumption of human milk oligosaccharides by gut-related microbes.	human milk contains large amounts of complex oligosaccharides that putatively modulate the intestinal microbiota of breast-fed infants by acting as decoy binding sites for pathogens and as prebiotics for enrichment of beneficial bacteria. several bifidobacterial species have been shown to grow well on human milk oligosaccharides. however, few data exist on other bacterial species. this work examined 16 bacterial strains belonging to 10 different genera for growth on human milk oligosaccharides. ...	2010	20394371
safety of probiotic escherichia coli strain nissle 1917 depends on intestinal microbiota and adaptive immunity of the host.	probiotics are viable microorganisms that are increasingly used for treatment of a variety of diseases. occasionally, however, probiotics may have adverse clinical effects, including septicemia. here we examined the role of the intestinal microbiota and the adaptive immune system in preventing translocation of probiotics (e.g., escherichia coli nissle). we challenged c57bl/6j mice raised under germfree conditions (gf-raised c57bl/6j mice) and rag1(-/-) mice raised under germfree conditions (gf-r ...	2010	20421387
ompa variants affecting the adherence of ulcerative colitis-derived bacteroides vulgatus.	to investigate the adhesion factor of bacteroides vulgatus derived from ulcerative colitis (uc), we isolated b. vulgatus strains from the large intestinal mucosa of uc patients and non-uc individuals, and examined their adherence to tissue-cultured cells. the adherence to tissue-cultured cells in uc-derived strains (36.5 +/- 7.9 %) was higher than that in non-uc-derived strains (13.2 +/- 7.7 %). pcr and sequencing analysis of outer membrane proteins revealed that the strains derived from five of ...	2010	20437766
[surgery in the treatment of patients with small cell lung cancer].	the data on surgical and combined treatment of 52 cases of small cell lung cancer are presented and the end results are evaluated. the findings on survival time make the case for surgery as a component of combined treatment of tumor. the best results were obtained in cases of stage i and ii tumor, absence of metastases into intrathoracic lymph nodes, tumor invasion limited to bronchopulmonary lymph nodes or the root of the lung, intermediate cell pattern of small cell lung cancer and surgery fol ...	2010	2998088
a distinctive 'microbial signature' in celiac pediatric patients.	celiac disease (cd) is an autoimmune disorder of the small intestine in which dietary gluten ingestion leads to a chronic enteropathy. recently, scientific evidence suggested a potential role of gut microbiota in cd. to have a snapshot of dominant duodenal microbiota we analyzed the mucosa-associated microbiota of 20 children with cd, before and after a gluten-free diet (gfd) regimen, and of 10 controls. total dna was extracted from duodenal biopsies and amplification products of 16s ribosomal d ...	2010	20565734
pyrosequencing study of fecal microflora of autistic and control children.	there is evidence of genetic predisposition to autism, but the percent of autistic subjects with this background is unknown. it is clear that other factors, such as environmental influences, may play a role in this disease. in the present study, we have examined the fecal microbial flora of 33 subjects with various severities of autism with gastrointestinal symptoms, 7 siblings not showing autistic symptoms (sibling controls) and eight non-sibling control subjects, using the bacterial tag encode ...	2010	20603222
german multicentre survey of the antibiotic susceptibility of bacteroides fragilis group and prevotella species isolated from intra-abdominal infections: results from the prisma study.	to determine the susceptibility of gram-negative anaerobic bacteria of the family bacteroidaceae from hospitalized patients with intra-abdominal infections (iais) to moxifloxacin and other antimicrobial agents with known activity against anaerobes.	2010	20851813
the structure of bvu2987 from bacteroides vulgatus reveals a superfamily of bacterial periplasmic proteins with possible inhibitory function.	proteins that contain the duf2874 domain constitute a new pfam family pf11396. members of this family have predominantly been identified in microbes found in the human gut and oral cavity. the crystal structure of one member of this family, bvu2987 from bacteroides vulgatus, has been determined, revealing a β-lactamase inhibitor protein-like structure with a tandem repeat of domains. sequence analysis and structural comparisons reveal that bvu2987 and other duf2874 proteins are related to β-lact ...	2010	20944221
intestinal bacteroides species associated with coeliac disease.	to characterise the predominant species of bacterial populations associated with duodenal biopsies of paediatric patients with active and treated coeliac disease.	2010	20972239