Publications

prevalence of bartonella henselae bacteremia, the causative agent of cat scratch disease, in an australian cat population.	in order to determine the prevalence of bartonella henselae becteremia in an australian cat population we examined blood cultures on a group of sydney cats. cats referred to the concord animal hospital for euthanasia were selected randomly for blood culture and serum sampling. blood samples were lysed and centrifuged and then cultured for up to five weeks. suspicious colonies were identified biochemically as probable b. henselae. selected isolates were confirmed as b. henselae using the polymera ...	1996	8912359
bacillary angiomatosis: microbiology, histopathology, clinical presentation, diagnosis and management.	bacillary angiomatosis is known to be caused by a rickettsial organism; rochalimaea henselae. this causative agent has been compared with different microorganisms and clinical conditions that appear in similar settings but that have been clearly differentiated from them; e.i. cat-scratch disease (afipia felis), bartonella bacilliformis, other rochalimaea sp., kaposi;s sarcoma, lobular capillary hemangioma, angiosarcoma, and epithelioid hemangioma. clinically the bacillary angiomatosis (ba) skin ...	1996	8916440
cloning, expression and sequence analysis of the bartonella henselae gene encoding the htra stress-response protein.	a cloned fragment of bartonella (rochalimaea) henselae (bh) dna was found to direct synthesis of an immunoreactive protein in escherichia coli (ec). sequence analysis revealed an open reading frame of 1509 nucleotides encoding a protein of 503 amino acids that exhibited extensive identity (over the entire protein) with the htra stress-response proteins of brucella abortus (59%), ec (37%) and salmonella typhimurium (36%). when the putative htra gene was amplified by polymerase chain reaction and ...	1996	8921888
isolation of bartonella quintana from an hiv-positive patient with bacillary angiomatosis.	bartonella quintana was grown from a lysis-centrifugation blood culture of an hiv-positive man who presented with lesions of bacillary angiomatosis in skin and bones. the isolate was identified by sodium dodecylsulfate-polyacrylamide gel electrophoresis, 16s rrna gene sequencing, and amplification of the enterobacterial repetitive intergenic consensus sequences.	1996	8922574
generalized infection with bartonella henselae following infection due to epstein-barr virus.		1996	8922830
[cat scratch disease. an overview for the ent physician].	background: cat scratch disease (csd) is a relatively common cause of chronic lymphadenopathy in the usa. in the present paper the authors describe recent advances in the understanding of this disorder focusing on etiology, clinical aspects, diagnostic management, and therapy. etiology: rochalimaea henselae and afipia felis, two gram-negative bacteria, have recently been isolated from lymph node tissue of patients suffering from csd. the current literature reveals that rochalimaea henselae seems ...	1996	8924168
[back again: the clothes louse (pediculus humanus var. corporis)].	in two homeless men aged 38 and 32 years, who suffered from itching, infestation with body lice (pediculus humanus var. corporis, a.k.a. clothes lice) was diagnosed. this infestation is rare in the netherlands. in 1993 and 1994 and infection with body lice was registered 41 times in 31 patients at the clinic for homeless of the community health service of utrecht. the body louse can be seen by the naked eye. treatment is by hygienic measures, pediculicides if necessary, and by prevention. import ...	1996	8927169
[endocarditis of negative blood culture: search in the intra-cell!].		1996	8942948
antibodies to bartonella species in inner-city intravenous drug users in baltimore, md.	bartonella quintana has recently been associated with homeless alcoholic men. both b quintana and bartonella henselae have been shown to be opportunistic pathogens of people with acquired immunodeficiency syndrome. the reservoirs and modes of transmission of these infections are incompletely known.	1996	8944742
experimentally induced bartonella henselae infections followed by challenge exposure and antimicrobial therapy in cats.	to elucidate kinetics of bartonella henselae bacteremia and igg response, evaluate antibiotic therapy, and investigate challenge exposure in cats.	1996	8950424
cat scratch disease: detection of bartonella henselae dna in archival biopsies from patients with clinically, serologically, and histologically defined disease.	serological and epidemiological studies suggest that bartonella henselae is the etiological agent of cat scratch disease. we designed a study to detect b. henselae in archival biopsies by polymerase chain reaction amplification of the 16s rrna gene followed by southern blot hybridization. forty-two histologically defined cat scratch disease biopsies and eighteen controls were selected for blinded analysis. after testing, charts were reviewed for clinical, immunological, and microbial evidence of ...	1996	8952548
[illnesses caused by bartonella. cat-scratch disease, bacillary angiomatosis, bacillary peliosis hepatis, endocarditis].		1996	8964682
[cat scratch disease in a 14-year-old boy].		1996	8975226
[cat-scratch disease as a diagnostic problem of lymphadenopathy].	the diagnosis of cat-scratch disease is based on history and clinical symptoms. we present a case of a 4-year-old girl admitted to our unit with suspicion of histiocytosis x after histologic evaluation of a submandibular lymph node biopsy. on the basis of history, clinical features and histologic reevaluation, the diagnosis of cat-scratch disease was made.	1996	8975227
bacillary angiomatosis in an hiv seronegative patient on systemic steroid therapy.	bacillary angiomatosis is an unusual systemic vascular proliferation seen predominantly in patients with the acquired immunodeficiency syndrome. these vascular lesions are due to infection with a bartonella species, most commonly b. henselae, but sometimes b. quintana. it is treatable and often curable, but without therapy may be life-threatening. clinically, the disorder often resembles several different vascular disorders, particularly pyogenic granuloma and kaposi's sarcoma. we now report a c ...	1996	8977724
[cat-scratch disease in humans and the cat's role. causative agents finally isolated].		1996	8984725
bartonella (rochalimaea) infections: beyond cat scratch.	five species of bartonella have been found to infect humans, henselae, quintana, elizabethae, bacilliformis, and vinsonii. the most common of these in north america are bartonella quintana and bartonella henselae, the agents of trench fever, bacillary angiomatosis, and parenchymal peliosis, and in the case of b. henselae cat-scratch disease. b. bacilliformis is endemic in peru and ecuador, where it causes oroya fever or carrion's disease. new methods of diagnosing bartonella infections have resu ...	1996	8712787
bartonella (rochalimaea) quintana causing fever and bacteremia in an immunocompromised patient with non-hodgkin's lymphoma.	a 48-yr-old man with stage iv non-hodgkin's lymphoma, became neutropenic following chemotherapy and developed a fever. his blood cultures were processed to enhance the yield of fastidious bacteria. a slow-growing, capnophilic gram-negative rod was isolated. the febrile episode was treated with cefotaxime, imipenem and vancomycin and resolved. the bacterial isolate was identified as bartonella (rochalimaea) quintana by 16s-rdna gene sequencing. the isolate showed 99.8% sequence homology with the ...	1996	8714279
bartonella infections.		1996	8718458
[detection of bartonella (rochalimaea) henselae/b. quintana by polymerase chain reaction (pcr)].	bartonella (rochalimaea) henselae and/or b. quintana are the causative agents of a variety of infections such as trench fever, bacillary angiomatosis, septicemia, peliosis hepatis and endocarditis. recently, b. henselae has been identified as a major cause of cat scratch disease. diagnosis of such infections is based on clinical information, histopathology, culture and serology. however, none of these methods alone is sufficiently sensitive or specific. we have used the pcr to search for dna spe ...	1996	8720724
q fever and trench fever.		1996	8727131
bacillary angiomatosis.		1996	8727133
bartonella (rochalimaea) quintana infection in a seronegative hemodialyzed patient.	bartonella quintana is a reemerging pathogen responsible for trench fever, endocarditis, bacteremia, and bacillary angiomatosis. we previously reported the first case of a patient with b. quintana-induced chronic adenomegaly, and here we present a report on a second patient. a hemodialyzed patient with sjögren's syndrome presented with mediastinal adenomegalies and secondary pancytopenia. all diagnostic investigations remained negative, except that a bartonella-like microorganism was isolated fr ...	1996	8727894
bartonella (rochalimaea) henselae hepatosplenic infection occurring simultaneously in two siblings.		1996	8729220
[visceral localizations of cat-scratch disease in an immunocompetent patient].	locoregional expression of cat scratch disease is well known, but despite advances in microbiology over the last 10 years leading to the description of two new bacteria (afipia felis, bartonella henselae) the infective agent responsible for cat scratch syndrome remains unknown. until the 80s, only one systemic disease was attributed to infection with a germ in the bartonella genus: trench fever. with the onset of the aids epidemic, new clinical syndromes caused by bartonella bacteria have been d ...	1996	8729380
acquisition of the cat scratch disease agent bartonella henselae by cat fleas (siphonaptera:pulicidae).	we assayed the ability of cat fleas to become infected with bartonella henselae, using an artificial feeding device. fleas fed a concentration of 1 x 10(5) cfu/ml in blood were examined using immunofluorescent antibody assay and polymerase chain reaction. bacteria were present in the gut at 3 h, and persisted up to 9 d after infection. qualitatively, the density of b. henselae was greater in the flea gut at 9 d, indicating that replication was occurring in the gut. b. henselae also was detected ...	1996	8667399
unknown species of rickettsiae isolated from ixodes ricinus tick in wałcz.	ticks ixodes ricinus have been harvested in park down-town wałcz in june 1994. presence of borrelia burgdorferi and rickettsiae has been tested with pcr. b. burgdorferi and coxiella burnetii have not been detected in any tick whereas characteristic for other rickettsiae dna fragment of gene encoding citrate-synthase has been found. bacterial strain has been cultured from the tick. biochemical properties of isolated strain has strongly suggested that these bacteria belong to genus bartonella (roc ...	1996	8673798
[cat scratch disease. atypical forms].	first described by robert debré in 1950, cat scratch disease, usually observed in children and young adults (80% of the case occur in subjects under 18), is the principal cause of chronic benign lymph node enlargement. the centers for disease control at atlanta currently recognize afipia felis and rochalimaea henselae as the causal agents of cat scratch disease. cats transmit the disease to humans by skin scratches or by licking open wounds. the bacilli can also be transmitted by dogs, monkeys, ...	1996	8685112
bilateral optic disc edema and multifocal retinal lesions without loss of vision in cat scratch disease.		1996	8694710
widespread cutaneous bacillary angiomatosis and a large fungating mass in an hiv-positive man.	bacillary angiomatosis (ba), an infection caused by a gram-negative rod, can be a multiorgan disease. the usual causative organism, bartonella (formerly rochalimaea) hensalae, has only recently been identified. bartonella quintana has also been shown to cause some cases of cutaneous ba. we describe a patient with widespread cutaneous ba with probable bone involvement and a large fungating mass.	1996	8698906
[bacillary angiomatosis, cat-scratch disease and trench fever: are these diseases caused by the same bacteria?].		1996	8553491
imaging manifestations of cat-scratch disease.	cat-scratch disease affects an estimated 22,000 people in the united states each year, more than half of whom are children or adolescents [1]. it is caused by bartonella henselae, a gram-negative bacillus usually introduced by the scratch of a cat [2]. in the past, diagnosis was made if three of the following four criteria were met: (1) history of cat exposure with inoculation, (2) positive skin test: (3) absent laboratory and histopathologic evidence of other diseases, and (4) biopsy findings o ...	1996	8553962
[infections dues to bartonella spp.].	the genus bartonella now includes four species which may infect humans : b. bacilliformis, b. quintana, b. henselae, and b. elizabethae. b. bacilliformis, the agent of carrion's disease, was the only species of the genus since 1993 when rochalimaea species were removed from the genus rochalimaea and included in the genus bartonella, within the family bartonellaceae. b. quintana is the etiologic agent of trench fever, bacillary angiomatosis, septicemia, endocarditis, and chronic lymphadenopathy. ...	1996	17292303
medical microbiology	rickettsiae are small, gram-negative bacilli that have evolved in such close association with arthropod hosts that they are adapted to survive within the host cells. they represent a rather diverse collection of bacteria, and therefore listing characteristics that apply to the entire group is difficult. the common threads that hold the rickettsiae into a group are their epidemiology, their obligate intracellular life ...	1996	21413251
bartonella henselae bacteraemia in domestic cats from auckland.	bartonella henselae causes most cases of cat scratch disease, a self-limited localised lymphadenopathy illness of humans. bartonella henselae also causes disseminated cutaneous and visceral disease in immunocompromised people. cat blood (1-5 ml) collected from cats in the auckland area was processed and plated on to 5% sheep blood brain heart infusion agar and incubated at 35 degrees c in 5% co2 for 14 days. bartonella henselae was identified by colony morphology, gram's stain, twitching motilit ...	1997	16031983
case records of the massachusetts general hospital. weekly clinicopathological exercises. case 2-1997. a 38-year-old man with digital clubbing, low-grade fever, and a murmur.		1997	8988901
epidemiologic evaluation of the risk factors associated with exposure and seroreactivity to bartonella vinsonii in dogs.	to determine seroprevalence to bartonella vinsonii subsp berkhoffii in a population of sick dogs from north carolina and virginia and to evaluate potential risk factors associated with increased likelihood of exposure to the organism.	1997	9140552
relapsing bacteremia after blood transmission of bartonella henselae to cats.	to determine persistence of bacteremia, pathogenicity, and immunoglobulin kinetics after blood transmission of bartonella henselae in cats.	1997	9140557
cat-scratch disease in a patient undergoing haemodialysis.		1997	9141021
a carboxy-terminal processing protease gene is located immediately upstream of the invasion-associated locus from bartonella bacilliformis.	a gene with homology to those encoding an unusual class of c-terminal processing proteases that flanks the invasion-associated locus ialab of bartonella bacilliformis has been identified. the 1302 bp gene, termed ctpa, is located immediately upstream of the iala gene and encodes a predicted nascent product of 434 amino acids, producing a mature protein of 411 amino acid residues. the bartonella ctpa appears to undergo autolysis in vitro, producing multiple products of 43-46 kda, and a second gro ...	1997	9141685
bacillary angiomatosis associated with myositis in a patient infected with human immunodeficiency virus.	a man with aids presented with a deep soft-tissue mass involving the right thigh. biopsy of a skin lesion on the back and culture of a specimen from this lesion showed bacillary angiomatosis due to bartonella (formerly rochalimaea) quintana. magnetic resonance imaging revealed a large heterogeneous mass involving the vastus medialis and intermedius muscles. therapy with erythromycin caused rapid resolution of both the cutaneous lesion and the muscle lesion. bartonella infection is proposed as an ...	1997	9145727
cat scratch disease in a child.	we report a case of a 9-year-old girl scratched on the right side of her neck by a kitten about one month prior to admission. she was well until three weeks later when she developed enlarged right neck masses, a pustula on the scratch site, right injected conjunctiva, headache, general malaise and fever, thus fulfilling the clinical criteria for csd. initially, she was treated by a practicing physician but the manifestations persisted for one week. after admission, leukocytosis and a mildly elev ...	1997	9151470
[2 patients with atypical manifestations of cat-scratch disease].	in 2 boys aged 8 years and 10 months, respectively, uncommon manifestations of cat scratch disease were seen. the first patient had acute encephalopathy: coma and generalized tonic-clinic convulsions. the second patient was presented with fever and peripheral lymphadenopathy in combination with hypodense lesions in the liver on ultrasound. diagnosis was established on the clinical picture and the positive results of serological testing of antibody titres for bartonella henselae. both patients re ...	1997	9157299
[visceral granulomas and pericardial effusion caused by a bartonella henselae infection].	a 57 year-old woman was seen after a three-week period of upper abdominal pain, nausea, fever, headache and exertional dyspnoea. laboratory examination showed an elevated esr and serum gamma-gt activity. the chest x-ray showed cardiomegaly resulting from a pericardial effusion as was demonstrated by echocardiography. an abdominal ct-scan disclosed multiple hypodense lesions in the liver and spleen and lymphadenopathy along the hepatoduodenal ligament. liver biopsy showed a necrotising granulomat ...	1997	9157300
cat scratch disease as a rare cause of obstructive jaundice: a case report.		1997	9157863
prevalence of bartonella henselae and bartonella clarridgeiae in stray cats.	the aim of the present work was to determine by blood culture the prevalence of blood infection with bartonella species in a well-defined, european, urban stray cat population. therefore, 94 stray cats were trapped from 10 cat colonies. blood samples of these cats were cultured on both blood agar and liquid medium in order to raise the likelihood of bacterial detection. fifty blood samples (53%) gave a positive culture result for bartonella species. isolate identification was performed by sequen ...	1997	9163438
seroprevalence of immunoglobulin g antibodies to bartonella henselae in cat owners.		1997	9177972
infective endocarditis due to unusual or fastidious microorganisms.	infective endocarditis due to fastidious microorganisms is commonly encountered in clinical practice. some organisms such as fungi account for up to 15% of cases of prosthetic valve infective endocarditis, whereas organisms of the hacek group (haemophilus parainfluenzae, h. aphrophilus, and h. paraphrophilus, actinobacillus actinomycetemcomitans, cardiobacterium hominis, eikenella corrodens, and kingella kingae) cause 3% of community-acquired cases of infective endocarditis. special techniques a ...	1997	9179137
bartonella infections.		1997	9189670
[cat-scratch disease--an overlooked disease in denmark?].	only one patient with cat-scratch disease (csd) has been reported in denmark. a case and retrospective investigation among patients admitted to the ward is presented. over a period of 3.5 years, six patients were found to have suffered from csd. the yearly incidence was calculated to 2.6/100,000. the patients were tested for antibodies against bartonella (rochalimaea) henselae with a new test developed at the danish serum institute. only two of the patients with csd had titres of antibodies high ...	1997	9190717
bartonella clarridgeiae, a newly recognized zoonotic pathogen causing inoculation papules, fever, and lymphadenopathy (cat scratch disease).	shortly after adopting a 6-week-old cat, a veterinarian was bitten on the left index finger. within 3 weeks, he developed headache, fever, and left axillary lymphadenopathy. initial blood cultures from the cat and veterinarian were sterile. repeat cultures from the cat grew bartonella-like organisms with lophotrichous flagella. sera from the veterinarian were not reactive against bartonella henselae, b. quintana, or b. elizabethae antigens but were seroreactive (reciprocal titer, 1,024) against ...	1997	9196200
culture-negative endocarditis: contribution of bartonella infections.	two cases of bartonella endocarditis are described: one in a 55 year old homeless alcoholic man, caused by bartonella quintana; the other in a 41 year old male with a history of exposure to cat fleas, caused by b henselae. serological testing and polymerase chain reaction of the excised valves were used to identify the organisms. false positive serology for chlamydia was detected in one case.	1997	9196420
detection of antibodies to bartonella henselae in clinically diagnosed cat scratch disease.	to determine the usefulness of an indirect immunoflourescence antibody test for antibodies to bartonella henselae in diagnosing cat scratch disease (csd).	1997	9196486
trench fever among homeless people in marseille, france: a seroprevalence survey.		1997	9196653
never discount an animal vector.		1997	9197061
[cat-scratch disease: historical, clinical, phylogenetic and taxonomic aspects].	the cat-scratch disease (csd) is known as a nosological entity since 1950. it was diagnosed by the clinical symptoms, epidemiologic data, and the intracutaneous test of hanger and rose. the aetiologic agent is bartonella (formerly rochalimaea) henselae occurring in thirty to fifty percent of healthy cats. the gramnegative alpha-2-proteobacteria cause the csd but also fever in healthy humans. patients suffering from aids show bacillary angiomatosis, bacillary peliosis hepatis, endocarditis, and s ...	1997	9198973
[cat scratch disease and associated infections].	cat scratch disease (csd) was first described in france by debré et al. in 1950, yet the causative bacterial agent of csd remained obscure until 1992, when bartonella (formerly rochalimaea) henselae was implicated in csd by serological and microbiologic studies. b. henselae had been linked initially to bacillary angiomatosis (ba), but also bacillary peliosis, relapsing bacteremia and endocarditis. cats are healthy carriers of b. henselae and b. clarridgeiae, and can be bacteremic for months to y ...	1997	9203735
molecular diagnosis of deep nodular bacillary angiomatosis and monitoring of therapeutic success.	a 51-year-old human immunodeficiency virus (hiv)-positive male patient (cdc stage 3c) had had a painful nodule on his external ankle joint for 10 months. a biopsy suggested bacillary angiomatosis, but kaposi's sarcoma could not be excluded. rods were detectable in lesional skin by a warthin-starry stain. a 298 base pair (bp) gene fragment specific for bartonella species was amplified from lesional skin and direct nucleotide sequence analysis of the amplification product clearly identified barton ...	1997	9205511
experimental infection of young specific pathogen-free cats with bartonella henselae.	eighteen 12-week-old specific pathogen-free cats, blood culture- and serum antibody-negative for bartonella henselae, were randomly allocated to groups and were intravenously inoculated with 10(10) (group 1), 10(8) (group 2), or 10(6) (group 3) b. henselae or with saline (group 4) or were not inoculated (group 5). cats were humanely killed at 2, 4, 8, 16, and 32 weeks after inoculation. all b. henselae-inoculated cats were bacteremic by 2 weeks after infection. bacteremia persisted until 32 week ...	1997	9207369
application of polymerase chain reaction assay in the diagnosis of orbital granuloma complicating atypical oculoglandular cat scratch disease.	parinaud oculoglandular syndrome is uncommon. most cases are caused by cat scratch disease (csd), recently discovered to be associated with the pathogen bartonella henselae. before isolation of the micro-organism, diagnosis relied on the presence of characteristic clinical features. however, atypical cases could cause diagnostic problems. with the development of an indirect fluorescent antibody test and polymerase chain reaction (pcr) assay, oculoglandular csd can be diagnosed readily.	1997	9224472
rapid polymerase chain reaction-based detection of the causative agent of cat scratch disease (bartonella henselae) in formalin-fixed, paraffin-embedded samples.	bartonella (formerly rochalimaea) henselae (bh) plays a central role in cat scratch disease. a polymerase chain reaction (pcr)-based assay that can detect bh dna in formalin-fixed, paraffin-embedded (ff-pe) samples would have utility in the evaluation of processed lymph nodes suggestive of this disorder. fresh or ff-pe cultures of bh and related species were analyzed. thirteen lymph nodes (12 ff-pe and one fresh cell suspension) with necrotizing suppurative granulomatous inflammation and seven f ...	1997	9224751
the 75-kilodalton antigen of bartonella bacilliformis is a structural homolog of the cell division protein ftsz.	a genomic library of bartonella bacilliformis was constructed and screened with human anti-bartonella serum from a patient with the chronic, verruga peruana phase of bartonellosis. an immunoreactive clone isolated from this library was found to code for a 591-amino-acid protein with a high degree of sequence similarity to the ftsz family of proteins. the degree of amino acid identity between the b. bacilliformis protein (ftsz[bb]) and the other ftsz proteins is especially pronounced over the n-t ...	1997	9226264
molecular diagnosis of cat scratch disease: a two-step approach.	amplification of bartonella henselae dna has been proposed as a diagnostic test for cat scratch disease (csd). the sensitivities of the following three pcr assays were compared. pcr/rrna with universal primers amplifies part of the 16s rrna gene, followed by hybridization with a specific b. henselae probe; pcr/cs and pcr/hsp amplify portions of the glta and the htra genes, respectively, each followed by restriction fragment length polymorphism analysis. the threshold of detection of b. henselae ...	1997	9230357
pitfalls and fallacies of cat scratch disease serology: evaluation of bartonella henselae-based indirect fluorescence assay and enzyme-linked immunoassay.	the diagnostic value of the detection of immunoglobulin g (igg) and igm by bartonella henselae-based indirect fluorescence assay (ifa) and enzyme-linked immunoassay (eia) for the diagnosis of cat scratch disease (csd) was evaluated. the ifa was performed either with b. henselae that was cocultivated for a few hours with vero cells or with noncocultivated b. henselae as the antigen. additionally, the performance of a bartonella pcr hybridization assay based on the 16s rrna gene was determined and ...	1997	9230358
pcr amplification and comparison of nucleotide sequences from the groesl heat shock operon of ehrlichia species.	degenerate pcr primers derived from conserved regions of the eubacterial groesl heat shock operon were used to amplify groesl sequences of ehrlichia equi, ehrlichia phagocytophila, the agent of human granulocytic ehrlichiosis (hge), ehrlichia canis, bartonella henselae, and rickettsia rickettsii. the groesl nucleotide sequences were less conserved than the previously determined 16s rrna gene sequences of these bacteria. a phylogenetic tree derived from deduced groel amino acid sequences was simi ...	1997	9230387
coinfection with bartonella clarridgeiae and bartonella henselae and with different bartonella henselae strains in domestic cats.	bartonella clarridgeiae and several strains of bartonella henselae, the agent of cat scratch disease, with variations in the 16s rrna gene have been found to infect the blood of cats. an epidemiologic study of bartonella infection in domestic french cats revealed that of 436 cats sampled, 5 cats (1.1%) were coinfected with b. henselae and b. clarridgeiae and 2 cats (0.5%) were coinfected with two strains of b. henselae with variations in the 16s rrna gene, b. henselae type i and type ii. in an i ...	1997	9230394
bartonellosis and human immunodeficiency disease (aids): l-forms as persisters, activating factors, and mechanism of disease.	bartonella, genus proteus, can cause immunodepressive disease. the organisms, in parasitized red blood cells, may invade the brain and every other system and space in the human body. bartonella henselae is proposed to have a role in the pathogenesis of acquired immunodeficiency syndrome (aids) encephalopathy. bartonella bacilliformis produces two known toxins that can induce spasm and angiomatosis, respectively, and manifest as diseases associated with symptomatic aids. the skin lesions of barto ...	1997	9247895
bacillary angiomatosis, cat-scratch disease, and bartonellosis: what's the connection?		1997	9248882
sternal abscess due to bartonella (rochalimaea) henselae in a renal transplant patient.	bartonella henselae, previously called rochalimaea henselae, is the causative agent of cat scratch disease (csd) in immunocompetent subjects and bacillary angiomatosis in immunocompromised ones. bone lesions are common in bacillary angiomatosis, but not in csd. we present the case of a patient with a renal transplant treated by immunosuppressive therapy who developed a sternal abscess with a histological pattern of csd. the ct pattern was that of a lytic bone lesion with adjacent fluid collectio ...	1997	9259103
immunologic response to bartonella henselae as determined by enzyme immunoassay and western blot analysis.	bartonella henselae is now regarded as the etiologic agent of cat-scratch disease and a cause of bacillary angiomatosis. we examined the human immune response to bartonella henselae infection using a newly developed enzyme immunoassay (eia) and a western blot procedure using outer-membrane proteins. the eia showed 98.6% and 91.4% agreement with an indirect fluorescence method (ifa) for detection of igm and igg antibodies, respectively. by using western blot analysis, reactivity to an 8-kd band s ...	1997	9260762
ease of isolation and semiquantitative culture of bartonella henselae from cats in melbourne.		1997	9271032
current knowledge of bartonella species.	bartonella species are now considered emerging pathogens. of the 11 currently recognized species, four have been implicated in human disease, although only two have been encountered in europe. bartonella quintana infections are now being diagnosed among the urban homeless and deprived, manifesting as trench fever, and bartonella henselae has been shown to be the causative agent of cat scratch disease. both species also cause a variety of hiv-associated infections, including bacillary anglomatosi ...	1997	9272384
heat shock response and groel sequence of bartonella henselae and bartonella quintana.	transmission of bartonella species from ectoparasites to the mammalian host involves adaptation to thermal and other forms of stress. in order to better understand this process, the heat shock response of bartonella henselae and bartonella quintana was studied. cellular proteins synthesized after shift to higher temperatures were intrinsically labelled with [25s]methionine and analysed by gel electrophoresis and fluorography. the apparent molecular masses of three of the major heat shock protein ...	1997	9274034
prevalence of bartonella species in domestic cats in the netherlands.	cats have been shown to provide the only known reservoir of bartonella henselae, the causative agent of cat scratch disease. to determine the prevalence of bartonella bacteremia and antibodies in dutch cats, blood samples from 113 cats from shelters (sheltered cats), 50 pet cats, and 25 specific-pathogen-free (spf) cats were analyzed. culture and subsequent pcr-restriction fragment length polymorphism (rflp) analysis of the 16s-23s rrna intergenic region and 16s rrna gene pcr-hybridization assay ...	1997	9276397
serological cross-reactions between bartonella and chlamydia species: implications for diagnosis.	diagnosis of chlamydia or bartonella infections continues to rely mainly on serology. however, serological cross-reactions between members of these genera have recently been described. sera from eight patients originally diagnosed as having chlamydia pneumoniae endocarditis reacted with both chlamydia sp. and bartonella quintana antigens (microimmunofluorescence technique). adsorption of sera with b. quintana or c. pneumoniae antigens removed anti-c. pneumoniae antibodies, whereas adsorption wit ...	1997	9276403
central nervous system infection associated with bartonella quintana: a report of two cases.		1997	9282717
hepatosplenic cat-scratch disease and abdominal pain.	there have been several recent reports that cat-scratch disease (csd) causes a multiplicity of atypical clinical syndromes. we recently diagnosed hepatosplenic csd in a child who was seen with fever and abdominal pain. we report this case and 10 other patients with hepatosplenic csd and highlight the importance of abdominal pain in this clinical entity.	1997	9076813
[cat-scratch disease. a report of 4 cases and a review of the literature].	four cases of cat-scratch diseases are here reported and a review of the literature is made. the disease, apart from its typical presentation form as a usually self-limited regional lymph node enlargement, can occasionally spread and involve several organs systems. indirect immunofluorescence serological tests have been of help for its diagnosis and should be included among the diagnostic criteria for the disease. in particular cases, nuclear magnetic resonance can be useful to suggests the diag ...	1997	9102668
cat-scratch disease and related clinical syndromes.	bartonella (rochalimaea) henselae is a common cause of cat-scratch disease. this newly identified bacterium is also the cause of several other clinical syndromes, including bacillary angiomatosis, bacillary peliosis hepatitis and splenitis, and acute and relapsing bacteremia. a high percentage of young cats carry b. henselae. fortunately, serious complications of b. henselae infections are rare in immunocompetent patients. cat-scratch disease is usually a self-limited illness that does not neces ...	1997	9105205
bartonella spp. as emerging human pathogens.	members of the genus bartonella (formerly rochalimaea) were virtually unknown to modern-day clinicians and microbiologists until they were associated with opportunistic infections in aids patients about 6 years ago. since that time, bartonella species have been associated with cat scratch disease, bacillary angiomatosis, and a variety of other disease syndromes. clinical presentation of infection with bartonella ranges from a relatively mild lymphadenopathy with few other symptoms, seen in cat s ...	1997	9105751
pathogenetic role of phagocytic abnormalities in human virus immunodeficiency infection: possible therapeutical approaches. a review.	polymorphonuclear cells (pmn) and monocytes/macrophages (m/m) represent the first defence line against invading microorganisms. both phagocytic cell functions are precociously compromised in human immunodeficiency virus (hiv)-infected subjects, thus leading to infectious and neurological complications in the late stages of disease. among intracellular pathogens, emerging bacteria such as bartonella henselae and rhodococcus equi can cause peculiar clinical pictures, i.e. the bacillary parenchimal ...	1997	9130002
[rickettsioses: the epidemiological assessment].	microbe of taxonomical families rickettsiaceae aceal and bartonellaceae of rickettsiales order have caused not less than 14 nosological forms of disease among people in different parts of the world. about 8 of them--in russia and in the former soviet republics. these diseases are not unequivocal from epidemiological point of view. trench, marseilles and other forms of fever, murine typhus, vesicules rickettsia, etc. have been liquidated and never recurred for 30-40 years. prowazek's [correction ...	1997	9424811
diagnostic and therapeutic challenges.		1997	9428019
[bartonella infections. former infectious diseases return].		1997	9432482
neuroretinitis and encephalopathy due to bartonella henselae infection.		1997	9448896
immunopurified extracellular bartonella henselae antigen for detecting specific antibodies by enzyme immunoassay.	protein antigens of bartonella henselae bacterial sonicate supernatant and concentrated cell-free culture filtrate were examined by sds-page. the sonicate supernatant gave 38 bands and the culture filtrate at least 21, of which 18 were of bacterial origin. immunoblotting against 13 monoclonal antibodies obtained from mice infected with live b. henselae showed that 10 of these antibodies reacted with a narrow 225 kda band and varying smears of bands ranging from 36 to 240 kda in the sonicate, but ...	1997	9463512
an outbreak of bartonellosis in zamora chinchipe province in ecuador.	we report an outbreak of human bartonellosis in zamora chinchipe province in ecuador, which occurred in 1995-1996. nineteen cases were seen, of which 18 presented with classical oroya fever (fever and profound anaemia) and one with verruga peruana; 11 of the cases (58%) had positive blood films containing bartonella bacilliformis. the houses of cases and neighbouring controls were visited; blood samples for thin films and cultures were collected from members of each house and a questionnaire was ...	1997	9463663
[emerging pathologies].		1997	9513170
[tropical animal and human rickettsial infections].	advances in molecular biology have provided tools that have greatly clarified our knowledge of rickettsial diseases. most rickettsias have been reclassified in the alpha subgroup of proteobacteria. four groups of rickettsias have been identified: the spotted fever group, the typhus group, ehrlichia, and bartonella. although still considered as a rickettsia, coxiella burnetti, the agent causing q fever, has been reclassified separately in the gamma subdivision of proteobacteria. recognition of ri ...	1997	9513175
bacillary angiomatosis and other bartonella species infections.	infections with organisms of the genus bartonella, for many years important only in south and central america, have assumed significance in developing countries, especially in conjunction with the advent of the pandemic of the human immunodeficiency virus infection. new molecular and culture techniques have determined that these organisms cause new diseases such as bacillary angiomatosis as well as diseases the etiology of which have been unknown such as cat scratch disease. in this article, the ...	1997	9300630
cloning, functional expression, and complementation analysis of an inorganic pyrophosphatase from bartonella bacilliformis.	we have cloned the inorganic pyrophosphatase gene (ppa) from the facultative intracellular pathogen bartonella bacilliformis and characterized its encoded product. the 531-bp gene is located approximately 1 kb downstream of, and in opposite orientation to, the invasion-associated locus (ialab) of b. bacilliformis. the predicted protein encoded by ppa is 177 amino acid residues, which is in agreement with in vitro and in vivo synthesis of a protein with an apparent molecular mass of 22-23 kda. th ...	1997	9304784
cat-scratch encephalopathy.	we present a case of cat-scratch disease in a 9-year-old girl, complicated by encephalopathy and seizures. bartonella (formerly rochalimaea) henselae is the causative agent in cat-scratch disease; methods now available for detection of this pleomorphic, gram-negative bacterium, including polymerase chain reaction amplification and indirect fluorescence antibody testing, may lead to changes in standard criteria used to verify a diagnosis of cat-scratch disease.	1997	9305359
human zoonotic infections transmitted by dogs and cats.	dogs and cats are the 2 most common household pets. however, they may be a direct or indirect source of human infections. this article aims to familiarize physicians with some common and uncommon bacterial, rickettsial, parasitic, and fungal zoonotic infections of dogs and cats. animal bites with or without infection continue to be a common problem. treatment of infected animal bites must include early debridement and concern for organisms from the mouth flora of the animal. the diagnosis and tr ...	1997	9308505
[atypical cat-scratch disease: a case report of splenic granulomatosis].	generally cat-scratch disease is a benign inflammatory adenopathy. the authors describe an atypical form of this disease, characterized by persistent fever and splenic granulomatosis requiring a diagnostic and therapeutic prolonged effort. they point out the important role of new immuno-fluorescent techniques to exactly identify the bacterium--bartonella henselae--causing cat-scratch disease and suggest to include cat-scratch disease among the causes of unknown origin fever.	1997	9312753
[late lymphoadenopathy in cat-scratch disease].		1997	9324701
seroprevalence of bartonella henselae infection and correlation with disease status in cats in switzerland.	the prevalence of infection with bartonella henselae was investigated in cats from different areas of switzerland. serum samples of 728 cats were examined for antibodies to b. henselae by immunofluorescent antibody testing, and the results were analyzed with a view to a possible correlation between a positive titer and signalment, clinical signs, infection with feline leukemia virus (felv), feline immunodeficiency virus (fiv), feline coronavirus (fcov), or feline spumavirus (fesfv), and the livi ...	1997	9350752
evaluation of commercial slides for detection of immunoglobulin g against bartonella henselae by indirect immunofluorescence.	four commercial slides were compared with in-house slides for the detection of immunoglobulin g (igg) against bartonella henselae in 58 healthy persons from a rural region by an indirect immunofluorescence assay. mrl-ba slides (mrl diagnostics, usa) and virion slides (virion, switzerland) with agar-derived bartonella henselae showed igg titers of > or = 1:256 in 44.8% and 51.7%, respectively, whereas bion slides (bios, germany), mrl-vero slides (mrl diagnostics), and in-house slides with cell-as ...	1997	9352257
bartonella henselae-associated acute multifocal retinitis in a patient with acquired immunodeficiency syndrome.		1997	9355199
analysis of 36-kilodalton protein (papa) associated with the bacteriophage particle of bartonella henselae.	a library of bartonella henselae dna was screened with antibody raised to the bacteriophage particle associated with this organism. a clone was isolated that expresses a 36-kd protein (termed papa for particle-associated protein) when examined by immunoblot analysis using antibody raised to the particle. southern blot hybridization indicates that the gene is present on the bacterial chromosome and packaged into the 14-kb particle-associated dna. a papa-specific probe hybridized to multiple bands ...	1997	9364933
american academy of dermatology 1997 awards for young investigators in dermatology. pathogenesis of bartonella henselae in cutaneous and systemic disease.		1997	9366828