Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| circulating iga, igg, and igm class antibody against haemophilus parainfluenzae antigens in patients with iga nephropathy. | we previously demonstrated a close relationship between the outer membranes of haemophilus parainfluenzae (hp) antigens (omhp) and iga nephropathy (igan). our objective was to clarify the relationship among iga, igg, and igm class antibody against omhp in the sera of 44 patients with igan and 62 patients with other glomerular diseases (ogd) by elisa. patients with igan showed a significantly higher level of iga antibodies (p less than 0.0005) and igg antibodies (p less than 0.001) against ohmp, ... | 1996 | 8625525 |
| [microbiological study of the respiratory tract in children with cystic fibrosis]. | pulmonary infections is a main cause of morbimortality in patients suffering from cystic fibrosis. the objective of this study was to know the flora implicated in respiratory pathology of all mucoviscidotic children attending hospital sant joan de déu of barcelona. | 1996 | 8695681 |
| [isolation of haemophilus influenzae and haemophilus parainfluenzae in genitourinary infections: a 4-year review]. | haemophilus spp. had been previously suggested as a potential pathogen in genitourinary infections that could be sexually transmitted. in order to check that suggestions we have determined the incidence, pathogenic role, possible sexual transmission and susceptibility to antibiotics in isolates of haemophilus parainfluenzae and haemophilus influenzae from genital tract infections. the microbiological samples were taken during a period of four years from patients attended in a service of sexual t ... | 1996 | 8695689 |
| occurrence of [copper, zinc]-cofactored superoxide dismutase in pasteurella haemolytica and its serotype distribution. | fifty-two ovine strains of pasteurella haemolytica and p. trehalosi representing serotypes 1-16 were examined for the presence of [copper, zinc]superoxide dismutase dna sequences. this was done using a combination of polymerase chain reaction with degenerate primers based on the sequence of the [cu,zn]superoxide dismutase gene (sodc) in related species and southern hybridization using a fragment of sodc from p. haemolytica a2 serotype as a probe. both detection methods identified a fragment of t ... | 1996 | 8759785 |
| haemophilus parainfluenzae biliary tract infections. | 1996 | 8784615 | |
| septic arthritis due to haemophilus parainfluenzae in a patients infected with the human immunodeficiency virus type 1. | 1996 | 8789888 | |
| in vitro activity of cefdinir against respiratory pathogens isolated in sicily with reference to beta-lactamase production. | the in vitro activity of cefdinir (ci-983, fk-482), an orally absorbed aminothiazolyl cephalosporin, was evaluated against all 287 strains of haemophilus influenzae, haemophilus parainfluenzae, moraxella catarrhalis, streptococcus pneumoniae and streptococcus pyogenes in comparison with cefaclor, cefuroxime, amoxicillin, amoxicillin-clavulanic acid, erythromycin and cotrimoxazole. the bactericidal activity of cefdinir, cotrimoxazole, amoxicillin-clavulanic acid and erythromycin was determined ag ... | 1996 | 8808715 |
| a multicentre collaborative study of the antimicrobial susceptibility of community-acquired, lower respiratory tract pathogens 1992-1993: the alexander project. | the alexander project is a unique, international, collaborative antimicrobial susceptibility surveillance study of bacterial pathogens causing community-acquired lower respiratory tract infection. fifteen centres, ten in the european union (eu) and five in the usa, each submitted up to 400 isolated per year for 2 years (1992 and 1993) to a central laboratory for re-identification and determination of mics of 15 antimicrobials using the sensititre microbroth incorporation technique. of the total ... | 1996 | 8858472 |
| in vitro activity of quinupristin/dalfopristin (rp 59500) against a large collection of infrequently isolated or tested species. | quinupristin/dalfopristin (rp 59500, synercid) is a parenteral streptogramin combination antimicrobial that possesses a synergistic and often bactericidal action against many grampositive species. in this study, a collection of 1270 uncommonly isolated or tested strains were evaluated for susceptibility to quinupristin/dalfopristin using agar dilution minimum inhibitory concentration (mic) methods described in the national committe for clinical laboratory standards. the greatest antimicrobial ac ... | 1996 | 8902412 |
| haemophilus parainfluenzae infective endocarditis. | gram-negative endocarditis was uncommon in the past, accounting for 1% to 3% of cases. with the advent of antibiotics, immunosuppressive agents and narcotic abuse, the number has increased to 5% to 10% in the native valves and as high as 17% in the prosthetic valves, with haemophilus species as the commonest aetiological agent, accounting for about 1% of the cases. we report a case of haemophilus parainfluenzae endocarditis in a 39-year-old man who presented with heart failure and persistent fev ... | 1996 | 8924025 |
| tetrameric repeat units associated with virulence factor phase variation in haemophilus also occur in neisseria spp. and moraxella catarrhalis. | the tetrameric repeat units 5'-caat-3' and 5'-gcaa-3' are associated with phase variable expression of lipopolysaccharide biosynthetic genes in haemophilus influenzae. four other tetrameric repeat units have also been reported from h. influenzae strain rd, 5'-caac-3', 5'-gaca-3', 5'-agct-3', and 5'-ttta-3', which are also associated with putative virulence factors. using oligonucleotide probes corresponding to five tandem copies of each of these tetramers, we have screened three strains of neiss ... | 1996 | 8935664 |
| role of iga, igg, and igm antibodies against haemophilus parainfluenzae antigens in iga nephropathy. | we have recently demonstrated glomerular deposition of outer membranes of haemophilus parainfluenzae (hp) antigens (omhp) and the presence of iga antibody against omhp in patients with iga nephropathy (iga-n). in this study, we analyzed iga-, igg-, and igm-classes of antibodies against omhp, and the relationship between these antibodies and renal lesions in iga-n. the subjects included 44 patients with iga-n and 62 patients with outer glomerular diseases (ogd); the latter group consisted of 23 p ... | 1996 | 8953116 |
| [therapeutic efficacy of azithromycin in pediatrics]. | azithromycin (azm), a newly developed azalide antibiotic, was administered at a standard dose of 10 mg/kg once daily for 3 days to pediatric patients with bacterial infections and the therapeutic efficacy of azm was investigated. 1. a total of 12 patients with the following diseases was evaluated: pharyngitis in two, tonsillitis in four, bronchitis in one, mycoplasma pneumonia in one, scarlet fever in two and enteritis in two. the drug was rated "excellent" in eight cases and "good" in four. 2. ... | 1996 | 8986555 |
| [clinical studies on azithromycin in pediatrics]. | fine granules or capsules of azithromycin (azm) were given to 32 pediatric patients for the treatment of the following diseases: pharyngitis in three cases; tonsillitis in one; bronchitis in six; pneumonia in six; mycoplasmal pneumonia in 14; pertussis and enteritis in one, each. effectiveness of azm was evaluated in 30 cases and the drug was rated "excellent" in 18 patients, "good" in 11 and "fair" in one, resulting in a total efficacy rate of 96.7%. three strains of bacteria were isolated from ... | 1996 | 8986557 |
| [pharmacokinetic and clinical evaluation of azithromycin using fine granules or capsules in the pediatric patients]. | azithromycin (azm), a new macrolide antibiotic, in fine granules and in capsules was studied for pharmacokinetic and clinical evaluations. 1. antibacterial activities. mic profile of azm was as follows: 0.78 approximately 1.56 micrograms/ml against staphylococcus aureus, < or = 0.025 approximately 0.10 microgram/ml against streptococcus pyogenes, 0.10 approximately 0.39 and 6.25 micrograms/ml against streptococcus pneumoniae, < or = 0.025 approximately 0.39 microgram/ml against moraxella(branham ... | 1996 | 8988410 |
| [a clinical evaluation of azithromycin in the treatment of pediatric infection]. | fine granule preparation of azithromycin (azm), a new macrolide antibiotic, was given to treat various infections in pediatric patients. efficacies of azm in a total of 21 patients (tonsillitis in six, bronchitis in five, pneumonia in five, impetigo contagiosa in three, staphylococcal scalded skin syndrome in one and bacterial enterogastritis in one) were rated "excellent" in 11 patients and "good" in eight. the remaining two cases were not included in the evaluation. azm eradicated all strains ... | 1996 | 8988413 |
| [urinary tract infection caused by haemophilus spp. in pediatrics: a rarely studied disease]. | haemophilus influenzae and haemophilus parainfluenzae have been, in very seldom times, described as a cause of urinary tract infection (uti), mainly on adults. their real incidence has been scarcely studied. in view of this situation, we have investigated the cases occurred during the year of 1994 in our hospital, in cádiz (spain). | 1996 | 9011206 |
| medical microbiology | the genus haemophilus includes a number of species that cause a wide variety of infections but share a common morphology and a requirement for blood-derived factors during growth that has given the genus its name. haemophilus influenzae, the major pathogen, can be separated into encapsulated or typable strains, of which there are seven types (a through f including e') based on the antigenic structure of the capsular polysaccharide, and unencapsulated or nontypable strains. type b h influenzae is ... | 1996 | 21413340 |
| collagenolytic activity of crevicular fluid and of adjacent gingival tissue. | the fluid in and gingival tissue lining periodontal pockets were collected from male patients undergoing periodontal therapy. the collagenolytic activity of the crevicular fluid, and the ability of the gingiva in culture to degrade (a) an exogenous collagen substrate, and (b) endogenous collagen newly synthesized and labeled with h3-hydroxyproline, were related to the severity of gingival inflammation. although inflammation appeared to have only a slight effect on gingival collagenolytic activit ... | 1996 | 229140 |
| progressive enlargement of an hepatic cell adenoma. | over a 5-mo period, an hepatic cell adenoma was noted to increase considerably in size, despite discontinuation of oral contraceptives. progressive tumor enlargement was documented by hepatic angiography, computed tomographic scan (ct scan) of the liver and 99mtc liver scan. the repeat hepatic angiogram also revealed that the tumor had become more vascular. multiple adenomas were in fact seen by all three techniques mentioned above. at surgery, seven hepatic cell adenomas were demonstrated, of w ... | 1997 | 499719 |
| endocarditis caused by haemophilus parainfluenzae identified by 16s ribosomal rna sequencing. | haemophilus parainfluenzae, a human commensal, is an infrequent cause of serious disease. a case of endocarditis caused by this organism in a five year old boy with complex congenital heart disease is reported. the course of this disease was very aggressive, leading to heart failure, disseminated intravascular coagulation and multiorgan failure in spite of appropriate antibiotics and surgical intervention. the difficulties in the detection and identification of h parainfluenzae using conventiona ... | 1997 | 9059363 |
| [maternal-fetal vertical transmission of haemophilus influenzae and haemophilus parainfluenzae]. | maternal-fetal transmission of haemophilus influenzae (hi) and haemophilus parainfluenzae (hpi) as well as characteristics of the infection in the neonate have been poorly described. | 1997 | 9069656 |
| infective endocarditis due to unusual or fastidious microorganisms. | infective endocarditis due to fastidious microorganisms is commonly encountered in clinical practice. some organisms such as fungi account for up to 15% of cases of prosthetic valve infective endocarditis, whereas organisms of the hacek group (haemophilus parainfluenzae, h. aphrophilus, and h. paraphrophilus, actinobacillus actinomycetemcomitans, cardiobacterium hominis, eikenella corrodens, and kingella kingae) cause 3% of community-acquired cases of infective endocarditis. special techniques a ... | 1997 | 9179137 |
| [pathogenesis of iga nephropathy: role of outer membranes of haemophilus parainfluenzae antigens]. | iga nephropathy is characterized by iga deposits, predominantly in the glomerular mesangium and mesangial proliferative glomerulonephritis. concerning its pathogenesis, several investigators suggest that the deposited iga is an antibody to viral, bacterial, or dietary antigens. such reports strengthen the possibility of a relationship between mucosal immunity and the pathogenesis of iga nephropathy. we previously observed that haemophilus parainfluenzae (hp) is more commonly isolated from the ph ... | 1997 | 9200951 |
| comparison of cefdinir and cefaclor in treatment of community-acquired pneumonia. | six hundred ninety patients were enrolled in a multicenter, randomized, double-blind trial comparing the efficacy and safety of cefdinir with those of cefaclor in the treatment of community-acquired pneumonia. patients received either 10 days of treatment with cefdinir (n = 347) at 300 mg twice daily or 10 days of treatment with cefaclor (n = 343) at 500 mg three times daily. microbiological assessments were performed on sputum specimens obtained at admission and at the two posttherapy visits, i ... | 1997 | 9210689 |
| cellulitis and myositis caused by agrobacterium radiobacter and haemophilus parainfluenzae after influenza virus vaccination. | agrobacterium radiobacter is a gram-negative aerobic bacillus that has been reported as a cause of disease only 36 times in the literature. more than half of the patients (25) have had bacteremia. peritonitis, urinary tract infection, endocarditis, and one case of cellulitis associated with bacteremia have also been reported. infection is often associated with immunosuppression and the presence of a plastic foreign body, such as central venous catheters, nephrostomy tubes, intraperitoneal cathet ... | 1997 | 9225903 |
| rapid, sensitive, microbial detection by gene amplification using restriction endonuclease target sequences. | the use of primers synthesized to eight class ii restriction endonuclease target sequences, from haemophilus parainfluenzae, escherichia coli, staphylococcus aureus, salmonella infantis, rhodobacter sphaeroides, klebsiella pneumoniae, bacillus amyloliquefaciens and proteus vulgaris for single and multiplex pcr identification of the organisms is discussed. results indicate that the method is sensitive and specific enough to detect single cells and attogram amounts of target dna. it has also been ... | 1997 | 9281417 |
| outer membrane protein d15 is conserved among haemophilus influenzae species and may represent a universal protective antigen against invasive disease. | we have cloned and sequenced the d15 gene from two strains of haemophilus influenzae type b (hib) and two strains of nontypeable h. influenzae (nthi). the nucleotide and deduced protein sequences of d15 are highly conserved, with only a small variable region identified near the carboxyl terminus of the protein. analysis of upstream sequences revealed that the h. influenzae d15 gene may be part of a large potential operon of closely spaced open reading frames, including one with significant homol ... | 1997 | 9284140 |
| in-vitro activity of spiramycin and metronidazole alone or in combination against clinical isolates from odontogenic abscesses. | one hundred and forty-eight isolates of bacteria from 20 intraoral odontogenic abscesses were tested for their susceptibility to spiramycin and metronidazole alone or in combination. all isolates, except rothia spp. (one), enterococcus avium (three), haemophilus parainfluenzae (one) and staphylococcus aureus (one) were sensitive to spiramycin and/or metronidazole. among the anaerobes, spiramycin as well as metronidazole showed good antimicrobial activity against species of prevotella, eubacteriu ... | 1997 | 9338486 |
| photodynamic destruction of haemophilus parainfluenzae by endogenously produced porphyrins. | bacterial resistance against antibiotic treatment is becoming an increasing problem in medicine. therefore methods to destroy microorganisms by other means are being investigated, one of which is photodynamic therapy (pdt). it has already been shown that a variety of gram-positive and gram-negative bacteria can be killed in vitro by pdt using exogenous sensitizers. an alternative method of photosensitizing cells is to stimulate the production of endogenous sensitizers. the purpose of this study ... | 1997 | 9372610 |
| efficacy and safety of grepafloxacin 600 mg daily for 10 days in patients with community-acquired pneumonia. | the efficacy and safety of grepafloxacin in treating patients with community-acquired pneumonia (cap) was assessed in an open-label, noncomparative study. patients (n = 273) received grepafloxacin 600 mg qd for 10 days. a total of 237 patients (87%) completed the study. in assessable patients, the clinical success rate at follow-up (4 to 6 weeks after the last dose) was 89% (211/238 patients). in microbiologically assessable patients, the eradication rate at follow-up was 95% (86/91 isolates). g ... | 1997 | 9385485 |
| [clinical study on azithromycin in 10% fine granules and 100mg capsules in the field of pediatrics]. | azithromycin (azm), a new oral macrolide antibiotic, in 10% fine granules or 100 mg capsules was given to pediatric patients to treat various infections. the following results were obtained in our studies of azm for its antibacterial activities against clinical isolates, its pharmacokinetics, its efficacy, and its safety. 1. mics of azm, erythromycin (em) and clarithromycin (cam) were determined against a total of 57 strains all at 10(6) cfu/ml. among gram-positive cocci, mics of azm ranged from ... | 1997 | 9634360 |
| genetic transformation in haemophilus parainfluenzae clinical isolates. | haemophilus parainfluenzae isolates recovered from patients with respiratory diseases were studied for their ability to undergo genetic transformation by isogenic dna. two chromosomal markers, streptomycin resistance and nalidixic acid resistance, were tested for transformation efficiencies in h. parainfluenzae recipients from three biotypes. most efficient in transformation was biotype ii, followed by biotype i, while biotype iii was nontransformable. lack of transformation was not owing to poo ... | 1998 | 9662612 |
| cefaclor: a contemporary look at susceptibility of key pathogens from around the globe. | the orally administered cephalosporin antibiotic, cefaclor, has been available for clinical use in many countries since 1979. because widespread antibiotic use is often cited as a factor in the emergence of bacterial resistance to antibiotics, we sought to determine the degrees of resistance to cefaclor expressed by key pathogens recently isolated in 10 countries widely distributed around the world. using the e-test, minimal inhibitory concentrations (mic) were determined for cefaclor and severa ... | 1998 | 9669643 |
| sparfloxacin vs ofloxacin in the treatment of acute bacterial exacerbations of chronic bronchitis: a multicenter, double-blind, randomized, comparative study. sparfloxacin multicenter abecb study group. | comparison of efficacy and safety of sparfloxacin vs ofloxacin for treatment of acute bacterial exacerbations of chronic bronchitis (abecb). | 1998 | 9674458 |
| antibody response in six hacek endocarditis cases under therapy. | the antibody response to bacteria of the so-called hacek group, i.e. haemophilus spp., actinobacillus actinomycetemcomitans, cardiobacterium hominis, eikenella corrodens and kingella kingae, was measured in sera of six patients with endocarditis. the corresponding isolates from their blood cultures were identified by conventional methods, including reactions for nitrate reduction and catalase as well as acid production from sugars. crude antigens were prepared by glycine extraction and sonificat ... | 1998 | 9674892 |
| cloning and sequencing of a 16s/23s ribosomal spacer from haemophilus parainfluenzae reveals an invariant, mosaic-like organisation of sequence blocks. | a 16s/23s ribosomal spacer from a haemophilus parainfluenzae rrn locus was cloned and sequenced. analysis of pcr-amplified genomic fragments showed that this region is strongly conserved among unrelated isolates; computer analysis of database homologies showed that the spacer consists of sequence blocks, arranged in a mosaic-like structure, with strong homologies with analogous blocks present in the spacer regions of haemophilus influenzae, haemophilus ducreyi and actinobacillus spp. it also con ... | 1998 | 9682479 |
| molecular epidemiology and phylogenetic analysis of haemophilus parainfluenzae from chronic obstructive pulmonary disease exacerbations. | this study was undertaken to characterize serial haemophilus parainfluenzae strains from epidemiologically unrelated chronic obstructive pulmonary disease (copd) patients and from healthy carriers. a comprehensive approach was used including different phenotypical and molecular typing methods: biotyping, antibiotyping, conventional ribotyping, pulsed field gel electrophoresis (pfge) assay, and pcr-ribotyping. conventional ribotyping and pfge analysis were confirmed as excellent procedures to dif ... | 1998 | 9690761 |
| [laboratory and clinical studies on tazobactam/piperacillin in the field of pediatrics]. | laboratory and clinical studies on tazobactam/piperacillin (taz/pipc), a combination drug of piperacillin (pipc) with the new beta-lactamase inhibitor tazobactam (taz), were carried out in the field of pediatrics. 1. after intravenous administration of taz/pipc at a dose of 25 mg/kg to one child, the peak plasma levels of taz and pipc were 24.4 micrograms/ml and 119 micrograms/ml respectively after 5 min. the half-lives of taz and pipc were 0.48 and 0.60 hours respectively. same as 50 mg/kg to t ... | 1998 | 9755829 |
| semisynthesis of cytotoxic proteins using a modified protein splicing element. | two cytotoxic proteins, bovine pancreatic ribonuclease a (rnase a), and a restriction endonuclease from haemophilus parainfluenzae (hpai), were produced using a novel semisynthetic approach that utilizes a protein splicing element, an intein, to generate a reactive thioester at the c-terminus of a recombinant protein. nucleophilic attack on this thioester by the n-terminal cysteine of a synthetic peptide ultimately leads to the ligation of the two reactants through a native peptide bond. this st ... | 1998 | 9827992 |
| etiology, susceptibility, and treatment of acute bacterial exacerbations of complicated chronic bronchitis in the primary care setting: ciprofloxacin 750 mg b.i.d. versus clarithromycin 500 mg b.i.d. bronchitis study group. | although controversial, antimicrobial therapy for the treatment of acute exacerbations of chronic bronchitis (aecb) appears beneficial in patients with a history of repeated infections, those who have comorbid illnesses, and those with marked airway obstruction. in a community-based, open, randomized trial, the efficacy and safety of ciprofloxacin (cip) 750 mg and clarithromycin (cla) 500 mg, each given twice daily for 10 days, were compared in 2180 patients with aecb (1083 cip, 1097 cla). patie ... | 1998 | 9829441 |
| [haemophilus parainfluenzae antigens in iga nephropathy]. | iga nephropathy (igan), a common glomerular disease, is characterized by the presence of iga deposits, predominantly in the glomerular mesangium, and by mesangial proliferative glomerulonephritis (gn). concerning its pathogenesis, several investigators suggest that the deposited iga is an antibody to viral, bacterial, or dietary antigens. thus the antibody is probably produced as part of the specific host immune response to various environmental antigens. such reports strengthen the possibility ... | 1998 | 9492534 |
| haemophilus parainfluenzae liver abscess after successful liver transplantation. | haemophilus parainfluenzae was isolated from a bile specimen and from an aspirate of a liver abscess in a 58-year-old liver-transplanted woman that was indicative of an invasion of the graft by an ascending route. drug therapy, immunosuppression, rejection therapy, and roux-en-y choledochojejunostomy may have contributed to the septic course. interdisciplinary cooperation was instrumental in diagnosis and successful management in this case. | 1998 | 9508321 |
| efficacy and tolerability of twice-daily ciprofloxacin 750 mg in the treatment of patients with acute exacerbations of chronic bronchitis and pneumonia. | in a review of the us bayer ciprofloxacin (cip) database, an analysis was undertaken to summarize the effectiveness and tolerability of cip 750 mg bid in the treatment of patients with acute exacerbations of chronic bronchitis (aecb) and pneumonia. in five controlled studies, comparator (comp) agents included ampicillin, intravenous cefuroxime/cefaclor, and other unspecified agents. primary efficacy end points were clinical success (resolution plus improvement) and bacteriologic eradication at t ... | 1998 | 9522111 |
| [infective endocarditis--a review of 21 cases in last 10 years]. | twenty one cases of infective endocarditis in last 10 years were re-evaluated by duke's criteria. fourteen strains of streptococcus viridans, 4 of enterococcus faecalis, 1 of haemophilus parainfluenzae were isolated from blood culture. as to the minimum inhibitory concentration (mic) of 8 strains of streptococci, imipenem revealed the lowest mic value, following penicillin g, ceftriaxon not equal to ampicillin, vancomycin and gentamicin. one strain of them was penicillin-resistant (0.8 microgram ... | 1998 | 9549176 |
| enzyme-mediated cytosine deamination by the bacterial methyltransferase m.mspi. | most prokaryotic (cytosine-5)-dna methyltransferases increase the frequency of deamination at the cytosine targeted for methylation in vitro in the absence of the cofactor s-adenosylmethionine (adomet) or the reaction product s-adenosylhomocysteine (adohcy). we show here that, under the same in vitro conditions, the prokaryotic methyltransferase, m.mspi (from moraxella sp.), causes very few cytosine deaminations, suggesting a mechanism in which m.mspi may avoid enzyme-mediated cytosine deaminati ... | 1998 | 9576871 |
| polymicrobial endocarditis with haemophilus parainfluenzae in an intravenous drug user whose transesophageal echocardiogram appeared normal. | 1998 | 9597274 | |
| ercp complicated by a retroperitoneal abscess caused by haemophilus influenzae and haemophilus parainfluenzae. | 1998 | 9609441 | |
| [experience with acetylsalicylic acid in long-term prevention of thrombosis in children]. | 1998 | 1219471 | |
| epidemiologic issues pertinent to international regulation of 28 stimulant-hallucinogen drugs. | this paper examines selected epidemiologic issues raised by the consideration of 28 stimulant-hallucinogen drugs for international drug control. new epidemiologic evidence on these drugs is presented, based on laboratory analysis of drug samples obtained from unauthorized channels of distribution in the united states. a proposal is made for experimental evaluation of international drug controls. the proposed approach is to select some of the stimulant-hallucinogen drugs which are not currently r ... | 1998 | 2874969 |
| breast-feeding protects against infection in indian infants. | a retrospective study was undertaken at two isolated manitoba indian communities to determine whether the type of infant feeding was related to infection during the first year of life. of 158 infants 28 were fully breast-fed, 58 initially breast-fed and then changed to bottle-feeding and 72 fully bottle-fed. fully bottle-fed infants were hospitalized with infectious diseases 10 times more often and spent 10 times more days in hospital during the first year of life than fully breast-fed infants. ... | 1998 | 106948 |
| [colorectal carcinomas. effect of early diagnosis on therapy]. | 1998 | 108583 | |
| [diagnosis of magnesium deficiency should be encouraged (proceedings)]. | 1998 | 108548 | |
| hyperprolactinemia and thyrotropin-releasing factor (trh) responses in men with alcoholic liver disease. | prolactin responses to provocative thyrotropin-releasing factor (trh) stimulation were evaluated in 43 chronic alcoholic men were divided into groups for analysis based on the presence or absence of gynecomastia and the histologic appearance of their livers as determined by percutaneous liver biopsy. compared to the normal volunteers, alcoholics with reversible liver disease (fatty liver) had reduced basal prolactin levels and exaggerated trh responses. in contrast, alcoholics with cirrhosis and ... | 1998 | 104634 |
| [biochemical diagnosis of gangliosidosis gm1]. | 1998 | 98915 | |
| [a family of von recklinghausen's disease combined with bilateral acoustic neurinomas (author's transl)]. | 1998 | 105303 | |
| studies on the allosteric properties of glycogen synthase i. | 1998 | 108102 | |
| observer variation in the interpretation of lower limb venograms. | after agreeing on diagnostic criteria and after a pilot study, two experienced radiologists twice independently reviewed 40 lower limb venograms performed by a standard technique in patients suspected or known to have venous thrombosis. the observers reviewed 20 examinations at a time, their analysis requiring separate identification of 11 major veins. at each site observers stated whether thrombus was "absent," "doubtful," "presumed," or "definite," or declared "no opinion possible." they then ... | 1998 | 105589 |
| contribution to the serological diagnosis of sarcocystosis. | the importance of the ifa-test (indirect fluorescent antibody test) in the diagnosis of sarcocystosis in the intermediate host has been confirmed in the present paper. we assessed the time of the first appearance of serum antibodies in the intermediate host in mice inoculated experimentally with the species sarcocystis dispersa. by means of the ifa-test, the first antibodies were found on day 20 p.i. cross-reactions among antisera of s. dispersa and a heterologous antigen of s. cernae disclosed ... | 1998 | 105972 |
| correlation of endotracheal tube size with sore throat and hoarseness following general anesthesia. | 1998 | 3307536 | |
| epinephrine prolongs lidocaine spinal: pain in the operative site the most accurate method of determining local anesthetic duration. | 1998 | 3307535 | |
| radiology societies. | 1998 | 104596 | |
| epidermal cytoplasmic antigens. | 1999 | 85677 | |
| successive generations of child maltreatment. the children. | families were identified, in north-east wiltshire (uk), (population 200,000), in which there was a pattern of two or more generations of child maltreatment and where there were also two or more children maltreated in the current generation (born between 1960 and 1980). these children had high rates of mental handicap, backwardness, and antisocial behaviour, and there were also characteristic patterns of emotional disturbance. the post-neonatal death rate for the 294 index children was very high, ... | 1999 | 3250697 |
| [the gluten-free diet in children]. | 1999 | 3250741 | |
| wholemeal bread and satiety. | 1999 | 89381 | |
| identification and affinity labeling of very high affinity binding sites for the phenylalkylamine series of ca+ channel blockers in the drosophila nervous system. | the interaction of putative ca2+ channels of drosophila head membranes with molecules of the phenylalkylamine series was studied from binding experiments using (-)-[3h]d888 and (+/-)-[3h]verapamil. these ligands recognize a single class (kd = 0.1-0.4 nm; bmax = 1600-1800 fmol/mg of protein) of very high affinity binding sites. the most potent molecule in the phenylalkylamine series was (-)-verapamil with a kd value as exceptionally low as 4.7 pm. molecules in the benzothiazepine and diphenylbuty ... | 1999 | 2827725 |
| plasma 1,25(oh)2 vitamin d concentrations in nutritional osteomalacia. | 1999 | 89299 | |
| formulation of an utterance by aphasics as response to stimuli of various grammatical categories. | 1999 | 93771 | |
| chlorpromazine excretion. ii. improved tlc procedures for fractionating the urinary drug content into chemical subgroups of cpz metabolites. | 1999 | 97047 | |
| effect on bone of withdrawal of oestrogen therapy. | 1999 | 89300 | |
| evidence for involvement of microtubules in the action of vasopressin in toad urinary bladder. ii. colchicine binding properties of toad bladder epithelial cell tubulin. | colchicine, podophyllotoxin and vinblastine have been found to inhibit the action of vasopressin on water movement in the toad urinary bladder. tubulin is the major colchicine binding component of toad bladder epithelial cells, accounting for approximately 3.3% of the total cell protein. more than 99% of the tubulin is found in the soluble fraction after sonication, the remainder is in the particulate fraction. similar to the characteristics of the binding of colchicine to tubulins from other so ... | 1999 | 96270 |
| [surgical palliative procedures in patients with carcinoma of the biliary tract (author's transl)]. | a report is given of 72 patients suffering from carcinoma of the extrahepatic biliary ducts. carcinoma of the gallbladder usually grow fast invading the surrounding tissue. thus cholecystectomy can be performed only as a pallouative procedure in most cases, and partial resection of the liver does not yield better results in general. carcinoma of the ductus hepaticus usually grows slowly and metastases are formed lately in the course; thus patients usually die due to occlusion of the ducts and ja ... | 1999 | 84316 |
| notification of hepatitis b. | 1999 | 89350 | |
| effectiveness of short-course therapy (5 days) with grepafloxacin in the treatment of acute bacterial exacerbations of chronic bronchitis. | three hundred eighty-nine patients were enrolled in a double-masked, multicenter, randomized clinical trial comparing the clinical and bacteriologic efficacies and safety of a 5-day course (n = 195) versus a 10-day course (n = 194) of grepafloxacin 400 mg once daily in the treatment of acute bacterial exacerbations of chronic bronchitis (abecb). patients in the 5-day treatment group received placebo on days 6 through 10. bacteriologic assessments were based on cultures of sputum specimens obtain ... | 1999 | 10090434 |
| management of acute exacerbation of chronic bronchitis. | in chronic bronchitis, a common respiratory illness marked by chronic productive cough and caused largely by cigarette smoking, bacterial exacerbations are thought to be a common cause of progressive airway damage. common bacterial pathogens, found in 50% to 60% of episodes, include haemophilus influenzae (the most common), as well as haemophilus parainfluenzae, streptococcus pneumoniae and moraxella catarrhalis. bacterial resistance to antibiotics, especially beta-lactam drugs such as amoxicill ... | 1999 | 10202233 |
| haemophilus influenzae localized in epithelial cell layers is shielded from antibiotics and antibody-mediated bactericidal activity. | nonencapsulated haemophilus influenzae frequently persists in the lungs of chronic obstructive pulmonary disease (copd) and cystic fibrosis (cf) patients for prolonged periods of time. the bacteria are not eradicated by antibiotic treatment of the patients or by specific antibodies that are found in the sputum and sera of these patients. we investigated whether h. influenzae, when localized in lung epithelial cell layers, is shielded from antibiotics and from antibody-mediated bactericidal activ ... | 1999 | 10222210 |
| [a consideration on the results of nationwide surveillance of antimicrobial susceptibilities--gram-negative bacilli]. | the results of the semi-annual nationwide surveillance of antimicrobial susceptibilities, conducted by the japanese ministry of health and welfare during the period of january 1993 to july 1995, were analyzed for typical gram-negative bacilli in the purpose of provision of an index for antimicrobial selection. during these 3 years, escherichia coli, citrobacter freundii, enterobacter aerogenes and proteus mirabilis showed slightly increasing tendency in susceptibility to fosfomycin (fom) and cit ... | 1999 | 10396690 |
| in-vitro antibacterial activity of levofloxacin against hospital isolates: a multicentre study. | the objective of this study was to evaluate the activity of the fluoroquinolone, levofloxacin, against hospital isolates of bacteria. mics of levofloxacin were determined for 2154 strains by agar dilution. breakpoints for susceptibility testing were calculated using the agar diffusion technique with 5 micrograms discs. the activity of levofloxacin against nalidixic acid- and pefloxacin-susceptible enterobacteriaceae (n = 668) was higher (mic50/90 0.06-0.12 mg/l) than previously reported for oflo ... | 1999 | 10404337 |
| biliary tract infection caused by haemophilus parainfluenzae. | haemophilus parainfluenzae was isolated from the bile specimens of 2 patients with acute cholecystitis. the strains were genetically unrelated by the random amplified polymorphic dna (rapd). the 2 h. parainfluenzae strains represented 11.7% of all positive bile cultures inoculated in blood culture bottles. the routine inoculation of bile specimens in media able to support growth of haemophilus species should be considered. | 1999 | 10447339 |
| peritonitis caused by haemophilus parainfluenzae in a patient undergoing continuous ambulatory peritoneal dialysis. | we report a case of peritonitis in a patient undergoing continuous ambulatory peritoneal dialysis. haemophilus parainfluenzae biotype iii was recovered in pure culture from dialysis fluid. | 1999 | 10449513 |
| [haemophilus parainfluenzae and iga nephropathy]. | iga nephropathy (igan) was first reported by berger in 1968, and characterized by diffuse iga deposition in the mesangium. patients with igan have usually episodic macroscopic hematuria accompanied with pharyngitis, gastroenteritis, bronchitis, or sinusitis. these findings suggest that igan is an immune-complex disease resulting from a poorly controlled mucosal immune response to environmental antigens to which the patient was chronically exposed. we reported the glomerular deposition of the out ... | 1999 | 10511804 |
| [haemophilus parainfluenzae and cholecystitis: description of one case and review of the literature]. | 1999 | 10563094 | |
| randomized, double-blind study of short-course (5 day) grepafloxacin versus 10 day clarithromycin in patients with acute bacterial exacerbations of chronic bronchitis. | the efficacy and safety of grepafloxacin were compared with clarithromycin in a randomized, double-blind, multicentre clinical trial of 805 patients with acute bacterial exacerbations of chronic bronchitis (abecb). patients were randomized to receive grepafloxacin 400 mg od for either 5 (n = 273) or 10 days (n = 268) or clarithromycin 250 mg bd for 10 days (n = 261). patients were assessed pre-treatment, 3-5 days during treatment, 1-3 days post-treatment and at follow-up (21-28 days post-treatme ... | 1999 | 10588313 |
| haemophilus parainfluenzae sepsis in a very low birth weight premature infant: a case report and review of the literature. | haemophilus parainfluenzae is an unusual cause of invasive bacterial disease and is particularly uncommon as a reported etiology of neonatal sepsis in current large published series. we describe a seriously ill, very low birth weight (vlbw) infant with documented early onset sepsis caused by h. parainfluenzae. we compare our case with those published previously and contrast the clinical presentation of infection in our patient to that of common bacterial pathogens causing neonatal sepsis. our re ... | 1999 | 10685246 |
| serological relationship of some v-factor dependent pasteurellaceae (haemophilus sp.) from guineapigs and rabbits. | culture of guinea pig and rabbit respiratory tracts for bacteria using x- (haemin) and v- (nad) factor in agar media detected infection by v-factor dependent pasteurellaceae (haemophilus sp.) in three colonies of guinea pigs and a group of rabbits. the 12 haemophilus strains comprised three api nh codes classed as haemophilus parainfluenzae and two codes classed as haemophilus aphrophilus/paraphrophilus. six cell wall lipid profiles were detected, but these were not related to api nh codes. both ... | 1999 | 10759399 |
| epidemiological studies of large resistance plasmids in haemophilus. | the distribution of large conjugative haemophilus influenzae plasmids in the nasopharyngeal haemophili of a group of people and in a large collection of 541 h. influenzae type b (hib) isolates was studied. a newly developed pcr-based assay was used to detect the plasmids. the target sequences were chosen from sequence analysis of part of p1056, a large multiresistance plasmid isolated from a clinical hib isolate, 1056. fifty-nine per cent of people were found to carry beta-lactamase-positive (be ... | 2000 | 10797080 |
| synthesis of immunoglobulins against haemophilus parainfluenzae by tonsillar lymphocytes from patients with iga nephropathy. | we previously demonstrated glomerular deposition of haemophilus parainfluenzae (hp) antigens and the presence of iga antibody against hp antigens in patients with iga nephropathy (igan). in this report we examine the synthesis of immunoglobulins against hp antigens in tonsillar lymphocytes from patients with igan. | 2000 | 10809801 |
| comparison of a 5 day regimen of cefdinir with a 10 day regimen of cefprozil for treatment of acute exacerbations of chronic bronchitis. | patients with acute exacerbations of chronic bronchitis were treated with cefdinir 300 mg bd for 5 days or cefprozil 500 mg bd for 10 days in a prospective, randomized, double-blind, multicentre study. of the 548 patients enrolled, 281 (51%) were evaluable. the clinical cure rates at the test-of-cure visit were 80% (114/142) and 72% (100/139) for the evaluable patients treated with cefdinir and cefprozil, respectively. respiratory tract pathogens were isolated from 409 (75%) of 548 admission spu ... | 2000 | 10837440 |
| the role of haemophilus parainfluenzae in copd | 2000 | 10843959 | |
| a case of haemophilus parainfluenzae pneumonia. | a 41 year old woman presented with community acquired pneumonia (cap) which failed to resolve following treatment with amoxycillin and cefaclor prior to referral. quantitative culture of sputum revealed a pure growth of haemophilus parainfluenzae and, following antibiotic susceptibility testing of the isolate, ciprofloxacin was prescribed resulting in resolution of the infection. immunological investigations showed that the patient had a high titre of h parainfluenzae specific igm. the combinati ... | 2000 | 10856326 |
| induction of iga against haemophilus parainfluenzae antigens in tonsillar mononuclear cells from patients with iga nephropathy. | much evidence suggests that iga production in vivo and in vitro is enhanced in patients with iga nephropathy (igan). we have demonstrated glomerular deposition of the outer membranes of haemophilus parainfluenzae (hp) antigens (omhp) and the presence of hp-specific iga in the serum of patients with igan. in this study, we investigated the production of iga and several cytokines by tonsillar mononuclear cells (tmc) from igan patients induced by stimulation with omhp. the spontaneous production of ... | 2000 | 10866131 |
| haemophilus parainfluenzae antigen and antibody in children with iga nephropathy and henoch-schönlein nephritis. | although the pathogenesis of immunoglobulin a (iga) nephropathy and henoch-schönlein nephritis (hsn) remains uncertain, there is substantial evidence that they are immune complex-mediated diseases. recently, haemophilus parainfluenzae antigens were shown in the glomerular mesangium of adult patients with iga nephropathy, and greater levels of iga antibody against h parainfluenzae were also shown in the sera of adult patients with iga nephropathy. the present study was performed to detect h parai ... | 2000 | 10873871 |
| do bacteria cause exacerbations of copd? | exacerbations of copd, which include combinations of dyspnea, cough, wheezing, increased sputum production (and a change in its color to green or yellow), are common. the role of bacterial infection in causing these episodes and the value of antibiotic therapy for them are debated. an assessment of the microbiological studies indicates that conventional bacterial respiratory pathogens, such as streptococcus pneumoniae and haemophilus influenzae, are absent in about 50% of attacks. the frequency ... | 2000 | 10893379 |
| a comparison of a five-day regimen of cefdinir with a seven-day regimen of loracarbef for the treatment of acute exacerbations of chronic bronchitis. | to compare the efficacy and safety of five-day cefdinir treatment with seven-day loracarbef treatment in patients with acute exacerbations of chronic bronchitis, 586 patients were enrolled in a multicentre, randomised, double-blind trial. patients received either five days of treatment with cefdinir (n = 291) at 300 mg twice daily or seven days of treatment with loracarbef (n = 295) at 400 mg twice daily. microbiological assessments were done on sputum specimens obtained at admission and at the ... | 2000 | 10954955 |
| production of interferon-gamma by tonsillar mononuclear cells in iga nephropathy patients. | much evidence, both in vivo and in vitro, suggests that patients with iga nephropathy (igan) have enhanced iga production. we hypothesized that haemophilus parainfluenzae (hp) in the tonsil plays an important role in the iga production of igan patients. in this study, we focused on interferon-gamma (ifn-gamma) and iga production by tonsillar mononuclear cells (tmc) in patients with igan. tonsillectomies were performed in patients with igan and chronic tonsillitis (ct). the induction of ifn-gamma ... | 2000 | 11039878 |
| airway inflammation and etiology of acute exacerbations of chronic bronchitis. | the etiologic role of bacterial pathogens isolated from sputum culture in 40 to 50% of acute exacerbations of chronic bronchitis (aecb) is controversial. if bacterial pathogens cause these aecb, they should be associated with greater neutrophilic airway inflammation than pathogen-negative exacerbations. | 2000 | 11115440 |
| absence of bacterial colonization of the airways after therapeutic rigid bronchoscopy without stenting. | following airway stenting, bacterial colonization of the airways with potentially pathogenic micro-organisms occurs within 4 weeks after treatment in the majority of patients. the objective of this study was to prospectively investigate whether nonstenting therapeutic rigid bronchoscopy (using laser, cryotherapy, mechanical dilatation or debridement) is followed by airway colonization or infection. protected specimen brush sampling of the central airways and quantitative culture were performed i ... | 2000 | 11292121 |
| diffuse chronic sclerosing osteomyelitis and the synovitis, acne, pustolosis, hyperostosis, osteitis (sapho) syndrome in two sisters. | two sisters with diffuse chronic sclerosing osteomyelitis of the mandible and the humerus and the synovitis, acne, pustolosis, hyperostosis and osteitis syndrome (sapho syndrome) are presented. the diagnoses of diffuse chronic sclerosing osteomyelitis at the age of 12 years and 27 years, respectively, were based on typical medical history, clinical symptoms and radiographic, histologic and scintigraphic findings. because skin lesions and scintigraphic enhancement of the sternoclavicular joints w ... | 2000 | 10691145 |
| respiratory pathogens: assessing resistance patterns in europe and the potential role of grepafloxacin as treatment of patients with infections caused by these organisms. | although most respiratory tract infections (rti) are caused by viruses, various bacteria, particularly streptococcus pneumoniae, haemophilus influenzae and moraxella catarrhalis, are common causes of community-acquired pneumonia, acute exacerbations of chronic bronchitis, otitis media and sinusitis. empirical antibiotic therapy of patients with rti must take account of the increasing prevalence of resistance among the predominant pathogens. europe-wide susceptibility surveillance studies have re ... | 2000 | 10719006 |