Publications

thiamin and pyridoxine requirements during intravenous hyperalimentation.	studies were undertaken to determine rational dosages of vitamin b1 and b6 during long-term intravenous hyperalimentation, using more sensitive techniques than formerly used to evaluate b1 and b6 status. a standard vitamin combination, type a, (usually commercially available products) has been used up to now because of convenience, disregarding the effects of long-term administration. this combination lacks biotin, folic acid, and vitamin e and contains from 10 to 100 times the dietary allowance ...	1998	105622
pharmaceutics: total parenteral nutrition in the cancer patient.		1998	105802
infusion hepatotomography for evaluation of obstructive jaundice.	total body opacification with high doses of a urographic contrast agent demonstrated dilated intrahepatic biliary ducts as branching or rounded lucencies in all of 18 patients with obstructive jaundice. dilated extrahepatic ducts were seen as tubular lucencies in 11 of 16 patients with distal common bile duct obstruction. in seven patients with nonobstructive jaundice and in a control group of 25, the biliary ducts were either normal or not seen. gallbladder size was also evaluated. the site of ...	1998	105580
[isolated aplastic anemia--a polyetiological syndrome].		1998	105498
radiology societies.		1998	104596
epidermal cytoplasmic antigens.		1999	85677
distinguishing unipolar and bipolar depression by thyrotropin release test.		1999	89464
successive generations of child maltreatment. the children.	families were identified, in north-east wiltshire (uk), (population 200,000), in which there was a pattern of two or more generations of child maltreatment and where there were also two or more children maltreated in the current generation (born between 1960 and 1980). these children had high rates of mental handicap, backwardness, and antisocial behaviour, and there were also characteristic patterns of emotional disturbance. the post-neonatal death rate for the 294 index children was very high, ...	1999	3250697
thyrotoxicosis during pregnancy.	the diagnosis of thyrotoxicosis during pregnancy is difficult on clinical grounds only. the determination of free thyroid hormones or free thyroid hormone indices is important and is possibly supplemented by the trh stimulation test. thyrotoxicosis during pregnancy should always be treated actively. the authors recommend subtotal thyroidectomy if there are indications for surgical therapy (nodular goitre or large diffuse goitre). otherwise treatment with thyrostatic agents is used. after operati ...	1999	84547
biogenic amines derived from tryptophan in systemic and cutaneous scleroderma.	blood levels of serotonin (5-ht) and urinary excretion of 5-hydroxyindole-acetic acid (5-hiaa), tryptamine (t), and indole-acetic acid (iaa) were determined in 39 cases of systemic scleroderma and in 7 cases of very severe cutaneous scleroderma. the t/iaa ratio was normal and serotonin elevated in mild and rather severe acrosclerosis alike, i.e. in systemic scleroderma with pronounced vascular involvement. the t/iaa ratio was increased and serotonin normal in severe acroscleroderma, representing ...	1999	84460
[preparing children for day care centers based on experience in the central bohemia region].		1999	3250744
social inequalities and health.		1999	89362
treatment of myasthenia gravis. report on 139 patients.	in the treatment of myasthenia gravis (mg) considerable progress has recently been achieved. our experience is based on the observation of 139 patients with an average follow-up of 3 years and 4 months. a treatment plan and results are presented. indications for thymectomy: all cases of mg in adult life, apart from ocular myasthenia without radiological thymoma and without electrophysiological and pharmacological signs of generalization; before puberty only cases with radiological thymoma and se ...	1999	93623
undiagnosed wilson's disease as cause of unexplained miscarriage.		1999	89484
intergenic complementation after fusion of fibroblasts from different patients with beta-galactosidase deficiency.		1999	103586
assembly of newly replicated chromatin.		1999	103629
the effect of bleomycin and irradiation on g2 progression.		1999	94055
medical womanpower.		1999	89418
[cases of leukemoid plasma cell reaction].		1999	94128
[comparative studies on the demonstrability of eosinophilic granuloma using biebrich's scarlet staining and adam's reaction].		1999	85391
[control and prevention of foot and mouth disease in the western hemisphere].		1999	85453
the chromosomal 2'-n-acetyltransferase of providencia stuartii: physiological functions and genetic regulation.	intrinsic chromosomal acetyltransferases involved in aminoglycoside resistance have been identified in a number of bacteria. in providencia stuartii, a chromosomal acetyltransferase (aac(2')-ia) has been characterized in detail. in addition to the ability to acetylate aminoglycosides, the aac(2')-ia enzyme has at least one physiological function, which is the acetylation of peptidoglycan. this modification is likely to influence the autolytic system in p. stuartii. the regulation of aac(2')-ia e ...	1999	9924143
activation of the 2'-n-acetyltransferase gene [aac(2')-ia] in providencia stuartii by an interaction of aarp with the promoter region.	the aac(2')-ia gene in providencia stuartii encodes a 2'-n-acetyltransferase capable of acetylating both peptidoglycan and certain aminoglycoside antibiotics. regulation of the aac(2')-ia gene is influenced in a positive manner by the product of the aarp gene, which encodes a small transcriptional activator of the arac (xyls) family. in this study, we demonstrate the sequence requirements at the aac(2')-ia promoter for aarp binding and activation.	1999	10390241
molecular characterization of the genera proteus, morganella, and providencia by ribotyping.	the so-called proteus-providencia group is constituted at present by three genera and 10 species. several of the recognized species are common opportunistic pathogens for humans and animals. different methods based on the study of phenotypic characters have been used in the past with variable levels of efficiency for typing some species for epidemiological purposes. we have determined the rrna gene restriction patterns (ribotypes) for the type strains of the 10 different species of the genera pr ...	1999	10449462
providencia stuartii genes activated by cell-to-cell signaling and identification of a gene required for production or activity of an extracellular factor.	by utilizing reporter transposons, five providencia stuartii genes that are activated by the accumulation of self-produced extracellular signals have been identified. these genes have been designated cma for conditioned medium activated. the presence of conditioned medium from stationary-phase cultures grown in rich media resulted in the premature activation of each gene in cells at early log phase, with activation values ranging from 6- to 26-fold. preparation of conditioned medium from an m9 s ...	1999	10572119
assessment of the potential for microbial resistance to topical use of multiple antimicrobial agents.	the goal of this study was to reduce the likelihood of the generation and/or persistence of bacterial resistance to some antimicrobial components contained in a topical antimicrobial mixture (neomycin, polymyxin b, mupirocin and ciprofloxacin) for use with cultured skin grafts, by substitution of alternative antimicrobials, specifically fusidic acid for mupirocin and ofloxacin for ciprofloxacin. the alternative agents failed to serve that purpose. however, with the exception of specific genera o ...	1999	10781215
the association of hla--b8 with atrophic thyroiditis.	one-hundred-and-forty-seven patients with autoimmune thyroiditis were studied with respect to hla antigens as they related to various clinical features. hla--b8 was found to be significantly increased among 59 patients with atrophic thyroiditis (57% vs. 26% for controls) but was identical to controls in 88 patients with goitrous thyroiditis (26%). no relation was found in either group between b8 and thyroid autoantibody titer or, in the case of goitrous thyroiditis, the rate of progression of th ...	1999	91210
c-3 substituted lawsonemonoximates of holmium(iii): synthesis, characterization, and antimicrobial activity.	a series of five new metal complexes of ho(iii) with c-3 substituted derivatives of lawsonemonexime (2-hydroxy-1,4-naphthalenediene-1-oxime) were synthesized. the compounds were characterized by melting point, elemental analysis, ir spectroscopy and magnetic susceptibility. the antimicrobial activity of the compounds were determined by disk diffusion method and broth micro-dilution techniques using mueller hinton medium against the following organisms: s. aureus atcc 6538p, klebsiella pneumoniae ...	2000	18475938
hhv-8 is not a cofactor in the pathogenesis of environmentally induced malignant pleural mesothelioma.	after the recognition of human herpes virus 8 (hhv-8) in kaposi's sarcoma lesions, this new virus has been shown to be associated with various types of malignancy. one of them, body cavity-based lymphoma, is a high grade b-cell lymphoma arising from the body cavities. similarly, mesothelioma is a tumour that originates from the serosal linings of the pleural, pericardial and peritoneal cavities. one of the striking characteristics of mesothelioma cells is the secretion of interleukin-6 (il-6). a ...	2000	10949869
identification of escherichia coli ubib, a gene required for the first monooxygenase step in ubiquinone biosynthesis.	it was recently discovered that the aarf gene in providencia stuartii is required for coenzyme q (coq) biosynthesis. here we report that yigr, the escherichia coli homologue of aarf, is ubib, a gene required for the first monooxygenase step in coq biosynthesis. both the p. stuartii aarf and e. coli ubib (yigr) disruption mutant strains lack coq and accumulate octaprenylphenol. octaprenylphenol is the coq biosynthetic intermediate found to accumulate in the e. coli strain an59, which contains the ...	2000	10960098
remaining problems in the prevention of rh0 isoimmunization.		2000	89700
[cerebral paragonimiasis. case report--ct scan findings, early diagnosis and treatment-- (author's transl)].		2000	94662
[bronchopulmonary tumors. epidemiology].		2000	86174
[quantitative determination of copper in urine by color reaction with lead diethyldithiocarbamate].		2000	90204
270-mhz nuclear-magnetic-resonance study on linear gramicidin a in dimethylsulfoxide. a new interpretation.	on the basis of the finding of two sets of coupling constants (8.8 hz and 6.7 hz) in the 270-mhz proton magnetic resonance spectra of linear gramicidin in dimethylsulfoxide and the comparison of its infrared spectrum with those of known conformations of alternating poly(gamma-benzyl-d-glutamate--gamma-benzyl-l-glutamate), it is proposed that the antibiotic has an ld-ribbon structure.	2000	86442
inhibition of antibody production in plasmacytoma cells. iii. interactions of suppressive and nonsuppressive dnp conjugates with mopc 315 cells.		2000	87442
correction of fallot's tetralogy after palliative operations.	during the period 1960 to 1978, 98 patients underwent intracardiac repair of fallot's tetralogy after palliative operations. preoperative symptoms were cyanosis, dyspnea, increased fatigue with squatting and hypoxic spells. the hemoglobin concentration varied from 19 to 22 g/100 ml. at correction only 65 of 95 shunts were patent and needed surgical closure. seventeen early deaths occurred (19%), the main causes being cardiac failure and arrhythmia. one patient died 3 years after correction from ...	2000	87399
two-week postnatal examination of infants.		2000	87641
fetal antigens and prenatal diagnosis.		2000	89698
comparison of a new sulfate-free polyethylene glycol electrolyte lavage solution versus a standard solution for colonoscopy cleansing.	a new sulfate-free polyethylene glycol electrolyte lavage solution (sf-els) for colonoscopy was formulated to taste better and have less net water and electrolyte secretion and absorption than a standard polyethylene glycolelectrolyte lavage solution (peg-els). at two centers, 157 patients were prospectively randomized to receive sf-els or peg-els to assess adequacy of preparation, patient tolerance, weight changes, and various hematologic and biochemical parameters. physician assessment of colo ...	2000	2365214
adenylate kinase in neurological diseases.		2001	90882
lymphocyte capping and carrier detection in duchenne muscular dystrophy.		2001	90791
[effect of the preparations adreson and decadron given to expectant mothers on the postnatal state of newborn infants].		2001	90637
research needs in low vision.	research needs are presented for several areas of low vision: (1) reading and learning, (2) new low-vision aids, (3) modifying the environment, (4) utilization of disciplines, (5) new technologies, and (6) integrating low-vision services.	2001	88182
in vitro and in vivo induction of effector t cells mediating dth responses to a protein and a synthetic polypeptide antigen.		2001	90558
individual mice recognize the complex nature of h-2 antigens; unexpected reactions (anti-kk) in anti-balb/c-h-2d sera produced in the balb/c-h-2db mutant.		2001	88092
[nuclear surface of buccal cells as a function of the nature of the stain. measurements with an image analyzing computer].	measure of nuclear areas was performed on buccal smears by the quantimet 720 image analysing computer. five different staining procedures were used and we consider that toluidin blue at ph 4 is the best for a fine quantitative caryometry.	2001	88973
[cancer of the prostate].		2001	90455
pattern of heart disease in adults of the nigerian savanna: a prospective clinical study.	the pattern of heart disease in 404 patients seen prospectively from the guinea savanna region of africa is presented. over 90% presented with cardiac failure. hypertension, peripartal cardiac failure (ppcf), congestive cardiomyopathy and rheumatic heart disease are major problems. the highest incidence of ppcf in the world probably occurs in this area but the prognosis is good. the reasons for this and the possible interrelationship of hypertension with cardiomyopathy and ppcf are discussed. in ...	2001	97946
isolation and identification of bacteria associated with adult laboratory mexican fruit flies, anastrepha ludens (diptera: tephritidae).	from the guts of new and old colonies (female and male) of mexican fruit flies, anastrepha ludens (diptera: tephritidae), we identified a total of 18 different bacterial species belonging to the family enterobacteriaceae, pseudomonadaceae, vibrionaceae, micrococcaceae, deinococcacea, bacillaceae, and the genus listeria. enterobacter, providencia, serratia, and staphylococcus spp. were the most frequently isolated genera, with citrobacter, streptococcus, aerococcus, and listeria found less freque ...	2001	11178731
new tem variant (tem-92) produced by proteus mirabilis and providencia stuartii isolates.	the sequences of the bla(tem) genes encoding tem-92 in proteus mirabilis and providencia stuartii isolates were determined and were found to be identical. except for positions 218 (lys-6) and 512 (lys-104), the nucleotide sequence of bla(tem-92) was identical to that of bla(tem-20), including the sequence of the promoter region harboring a 135-bp deletion combined with a g-162-->t substitution. the deduced amino acid sequence of tem-92 differed from that of tem-52 by the presence of a substituti ...	2001	11257046
role of sspa in the density-dependent expression of the transcriptional activator aarp in providencia stuartii.	the aarp protein in providencia stuartii encodes a small transcriptional activator which activates the chromosomal aminoglycoside acetyltransferase aac(2')-ia gene. in addition, aarp activates genes involved in a multiple antibiotic resistance (mar) phenotype. expression of an aarp-lacz fusion increased in a density-dependent manner and reached peak levels at stationary phase. the expression of an aarp-lacz fusion could be prematurely activated in cells at early to mid-exponential phase by the a ...	2001	11257543
comparative in vitro activity of gemifloxacin, ciprofloxacin, levofloxacin and ofloxacin in a north american surveillance study.	the in vitro activity of gemifloxacin, a new fluoroquinolone, was compared to three marketed fluoroquinolones; ciprofloxacin, levofloxacin and ofloxacin against over 4,000 recent clinical isolates covering 29 species isolated in the united states and canada between 1997-1999. based on mic(90)s, gemifloxacin was the most potent fluoroquinolone tested against a majority of gram-positive isolates: streptococcus pneumoniae, penicillin resistant s. pneumoniae, macrolide resistant s. pneumoniae, cipro ...	2001	11448564
overexpression and characterization of the chromosomal aminoglycoside 2'-n-acetyltransferase of providencia stuartii.	the gene coding for aminoglycoside 2'-n-acetyltransferase ia [aac(2')-ia] from providencia stuartii was amplified by pcr and cloned. the resulting construct, packf2, was transferred into escherichia coli for overexpression of aac(2')-ia as a fusion protein with an n-terminal hexa-his tag. the fusion protein was isolated and purified by affinity chromatography on ni(2+)-nitrilotriacetic acid agarose and gel permeation chromatography on superdex 75. comparison of the specific activity of this enzy ...	2001	11451680
further studies on rpos in enterobacteria: identification of rpos in enterobacter cloacae and kluyvera cryocrescens.	rpos, the alternative sigma factor sigma(s), is important for bacterial survival under extreme conditions. many enterobacteria are opportunistic human pathogens and their ability to survive in a changing environment could be an essential step for their virulence. to determine the presence of this gene in enteric bacteria, an escherichia coli rpos probe was constructed and used to detect the presence of this gene in different species. a gene homologous to rpos was found in citrobacter amalonaticu ...	2001	11491080
intervening sequences in rrl genes and fragmentation of 23s rrna in genera of the family enterobacteriaceae.	intervening sequences (ivss) in the rrl genes for 23s rrna are transcribed but later removed by rnase iii without religation during rna processing, leading to fragmented rrna. we examined about 240 strains of the family enterobacteriaceae for presence of ivss using pcr. no ivss were detected in strains belonging to escherichia, shigella, enterobacter, erwinia, ewingella, hafnia, kluyvera, morganella, pantoea, or serratia. previously unreported ivss were detected in klebsiella oxytoca, citrobacte ...	2001	11544246
acid phosphatase/phosphotransferases from enteric bacteria.	we have investigated the enzymatic phosphorylation of nucleosides and found that morganella morganii phoc acid phosphatase exhibits regioselective pyrophosphate (pp(i))-nucleoside phosphotransferase activity. in this study, we isolated genes encoding an acid phosphatase with regioselective phosphotransferase activity (ap/ptase) from providencia stuartii, enterobacter aerogenes, escherichia blattae and klebsiella planticola, and compared the primary structures and enzymatic characteristics of the ...	2001	16233057
prevalence of extended spectrum beta-lactamases among enterobacteriaceae: an italian survey.	the prevalence of extended-spectrum beta-lactamase (esbl) production by consecutive non-repeated isolates of enterobacteriaceae was determined over a 6-month period. a total of 8015 strains were isolated from ten italian laboratories and 509 (6.3%) of these were designated esbl producers from the results of a double-disk synergy test. escherichia coli was the most isolated microrganism, followed by klebsiella pneumoniae and proteus mirabilis. providencia stuartii (28.1%) was the most frequently ...	2002	11932144
susceptibility of antibiotic-resistant gram-negative bacteria to biocides: a perspective from the study of catheter biofilms.	bacteria resistant to both the agents deployed to prevent infections and those used to treat infections would be formidable nosocomial pathogens. the aim of this paper is to review the evidence that gram-negative bacteria resistant to antibiotics and biocides have emerged and been responsible for catheter-associated urinary tract infection. a study of patients undergoing intermittent bladder catheterization revealed that the frequent application of the antiseptic chlorhexidine to the perineal sk ...	2002	12000625
resistant pathogens in urinary tract infections.	antimicrobial susceptibility of bacteria causing urinary tract infection (uti) has evolved over several decades as antimicrobial exposure has repeatedly been followed by emergence of resistance. older populations in the community, long-term care facilities, or acute care facilities have an increased prevalence of resistant bacteria isolated from uti. resistant isolates are more frequent in long-term care populations than the community. resistant isolates include common uropathogens, such as esch ...	2002	12121518
urea-dependent signal transduction by the virulence regulator urer.	identification of the environmental triggers involved in the expression of virulence genes is a fundamental objective in studies of bacterial pathogens. for uropathogens, urea, found in the urinary tract at concentrations of up to 500 mm, functions as an environmental signal. urea freely diffuses into the bacterium providencia stuartii and activates urer, a member of the arac family of transcriptional activators. active urer promotes transcription of virulence-associated urease genes and alerts ...	2002	12147687
a conserved mechanism for extracellular signaling in eukaryotes and prokaryotes.	epidermal growth factor receptor (egfr) is a key mediator of cell communication during animal development and homeostasis. in drosophila, the signaling event is commonly regulated by the polytopic membrane protein rhomboid (rho), which mediates the proteolytic activation of egfr ligands, allowing the secretion of the active signal. until very recently, the biochemical function of rho had remained elusive. it is now believed that drosophila rho is the founder member of a previously undescribed fa ...	2002	12221285
conservation of intramembrane proteolytic activity and substrate specificity in prokaryotic and eukaryotic rhomboids.	rhomboid is an intramembrane serine protease responsible for the proteolytic activation of drosophila epidermal growth factor receptor (egfr) ligands. although nothing is known about the function of the approximately 100 currently known rhomboid genes conserved throughout evolution, a recent analysis suggests that a rhomboid from the pathogenic bacterium providencia stuartii is involved in the production of a quorum-sensing factor. this suggests that an intercellular signaling mechanism may have ...	2002	12225666
clustering of bloodstream infections during maggot debridement therapy using contaminated larvae of protophormia terraenovae.	the treatment of human wounds with fly larvae is an ancient procedure recently reintroduced into medical practice under the term of biosurgery. the crucial technical problem of biosurgery is asepsis of the larvae.	2002	12382092
susceptibility of antibiotic-resistant gram-negative bacteria to biocides: a perspective from the study of catheter biofilms.	bacteria resistant to both the agents deployed to prevent infections and those used to treat infections would be formidable nosocomial pathogens. the aim of this paper is to review the evidence that gram-negative bacteria resistant to antibiotics and biocides have emerged and been responsible for catheter-associated urinary tract infection. a study of patients undergoing intermittent bladder catheterization revealed that the frequent application of the antiseptic chlorhexidine to the perineal sk ...	2002	12481841
[side-effects of chloramphenicol therapy].		2002	132775
benefit-cost and cost-effectiveness analysis: theory and application.	benefit-cost analysis and cost-effectivensss analysis are terms used with increasing frequency by health planners and those concerned with review and evaluation of specific programs. the economic bases for these formal techniques are however often obscured by adaptations of convenience or misapplications of the concepts by biological scientists (and others). this paper reviews briefly the theory of benefit-cost analysis and its potential as a tool in choosing programs of optimum size, of maximum ...	2002	118068
problems of classification of low-back pain.		2002	139668
[clinical and biological aspects of chronic brucellosis].	the present study refers to 53 cases of chronic brucellosis admitted to the clinic or followed up in an out-patient unit for ten years (1962-1971). there was a total of 946 days in hospital and 1688 days of occupational disability, about 40% of the patients necessitating repeated hospitalization because of the relapsing course of the disease. this group of cases presented the classical dominant features of an occupational anthropozoonoses (90.5%). elements of visceral and tissular pathology, obv ...	2002	128800
[primary disability of patients with bone fractures in saratov].		2002	126406
[pure red cell aplasia--report of a case and review of 158 cases in japan (author's transl)].		2002	395331
malpractice--the patient pays!!		2002	127365
[experience in combination of the educational and scientific work of students].		2002	127158
a symposium on the chronic pain syndrome in problem low back cases. psychiatric evaluation and feasibility of psychiatric therapy.		2002	127024
design of living environments for nursing-home residents: increasing participation in recreation activities.	nursing-home residents have frequently been characterized as unoccupied and disengaged. at the outset of the present study, most residents were to be found in their own rooms, not exhibiting gross motor behavior or social interaction, and not participating in appropriate activities. to modify residents' levels of participation with the environment, a manipulative area was provided in the lounge. participation in the lounge averaged 20% on days when the activity was not available, but increased t ...	2002	126983
[a phytobezoar in the choledochous duct].		2002	129423
interaction of inflammatory cells and oral microorganisms. vi. exocytosis of pmn lysosomes in response to gram-negative plaque bacteria.		2002	153390
how does the depressed patient fare in a family practice?		2003	194945
the biochemistry of sugars.	in animal cells the utilization of sugars involves one or more of the three major pathways known to occur in these cells. the glycolytic (embden-meyerhof) pathway is quantitatively the most important, and this pathway, coupled to the citric acid cycle, serves as a major source of energy. glycolysis and the citric acid cycle also provide most of the precursors for the synthesis of proteins, nucleic acids and lipids. the pentose phosphate, or hexose monophosphate oxidation, pathway is a major sour ...	2003	182650
[prevention of transmission of hepatitis by hb antigen carriers].		2003	253776
[melanotic progonoma. report of two cases (author's transl)].		2003	182628
changes in the glomerular pore size selectivity in patients with type ii diabetes mellitus.	we measured the urinary excretion rate and clearance of three plasma proteins, albumin, transferrin, and igg4, each of which has a similar isoelectric point, but a different molecular weight. this study consisted of 86 patients with type ii diabetes mellitus and 15 healthy subjects. in the patients, the degree of the urinary excretion rate and clearance of both transferrin (ter and ctrans) and igg4 igg4 er and clgg4) closely correlated with that of the urinary excretion rate of albumin (aer). al ...	2003	1770023
the use of the full thickness skin graft in dupuytren's contracture.	for those hand surgeons who have experienced early complications associated with limited fasciectomies (those who have not, have not done enough limited fasciectomies) and are frustrated by a high rate of recurrence or extension of the disease, incision of the cord and interposition of a full thickness graft is a technique to seriously consider. the procedure is not difficult to perform, but patience and attention to detail are prerequisites for success. that success is measured by complete or n ...	2003	1769995
studies on a transplantable murine rhabdomyosarcoma.	well-differentiated rhabdomyosarcomas developed in 8 of 10 balb/c mice inoculated with cell-free extracts of two lesions arising in bats previously inoculated with the moloney strain of murine sarcoma virus. the tumors could be transplanted in balb/c mice and other strains of mice compatible at the h-2 locus. a tumorigenic clonal cell culture line (r2) was established from a transplanted tumor. ultrastructural studies of the primary and transplanted tumors and r2 cells revealed thick and thin my ...	2003	165312
[echocardiography: iii--myocardiopathies].		2003	161966
histochemical and ultrastructural properties of myoid cells in the thymus of the frog.	histochemical and ultrastructural properties of myoid cells in the thymus of the frog were investigated and compared with properties of skeletal muscle fibres. the histochemical reactions of phospholipids, phosphorylase, succinic dehydrogenase and adenosine triphosphatase activities in myoid cells were characterized by considerable variability. individual myoid cells apparently possess different enzyme activities which correspond to different stages of development, maturity and degeneration of t ...	2003	156583
steroid addiction.		2003	153891
[malignant neoplasms among ethnic groups in the kazakh ssr].	the author has analysed the incidence of 40 nosological forms of malignant neoplasms among 4 conventionally selected ethnic groups of the kazakh ussr population, the latter was found to differ from other ethnic groups by a rather high incidence of esophageal cancer. also, malignant tumors of the stomach, liver, and biliary tract, the lung and bones are not infrequently observed amont the kazakh population. the representatives of other nationalities inhabiting the kazakh republic most often devel ...	2003	150125
the attack mechanism of an exo-1,3-beta-glucosidase from basidiomycete sp. qm 806.	the attack mechanism of a purified exo-1,3-beta glucosidase (1,3-beta-d-glucan glucohydrolase, ec 3.2.1.58) was investigated by using as a substrate a mixture of two structurally characterized periodate-oxidized and reduced unbranched 1,3-beta-d-glucans which differed only at the reducing terminal. the substrates, derivatives of laminarin, were altered only at the terminals due to resistance of the internal (1 leads to 3)-linked glucosyl residues to periodate oxidation. each glucan has only a si ...	2003	164221
enhancement of lymphocyte and macrophage function in vitro by lithium chloride.		2003	149624
ami quietly establishes multiple foreign footholds.		2003	153459
the rhomboids: a nearly ubiquitous family of intramembrane serine proteases that probably evolved by multiple ancient horizontal gene transfers.	the rhomboid family of polytopic membrane proteins shows a level of evolutionary conservation unique among membrane proteins. they are present in nearly all the sequenced genomes of archaea, bacteria and eukaryotes, with the exception of several species with small genomes. on the basis of experimental studies with the developmental regulator rhomboid from drosophila and the aara protein from the bacterium providencia stuartii, the rhomboids are thought to be intramembrane serine proteases whose ...	2003	12620104
an integron cassette encoding erythromycin esterase, ere(a), from providencia stuartii.	we have mapped the variable region of the two class 1 integrons found in the multiresistant strain providencia stuartii 1723. integron 1 contains a new arrangement of gene cassettes, aaca4-aadb-aada1, conferring resistance to all aminoglycosides used for clinical treatment. integron 2 contains a variant of the gene cassette ere(a), coding for an erythromycin esterase, whose nucleotide sequence shares 93.7% dna identity with ere(a) from escherichia coli bm2195 plasmid pip1100.	2003	12654734
characterization of clinical isolates of enterobacteriaceae from italy by the bd phoenix extended-spectrum beta-lactamase detection method.	production of extended-spectrum beta-lactamases (esbls) is an important mechanism of beta-lactam resistance in enterobacteriaceae: identification of esbls based on phenotypic tests is the strategy most commonly used in clinical microbiology laboratories. the phoenix esbl test (bd diagnostic systems, sparks, md.) is a recently developed automated system for detection of esbl-producing gram-negative bacteria. an algorithm based on phenotypic responses to a panel of cephalosporins (ceftazidime plus ...	2003	12682131
escherichia coli 83972 inhibits catheter adherence by a broad spectrum of uropathogens.	the presence of a nonpathogenic organism on the surface of a urinary catheter might impede catheter colonization by pathogens and thus prevent urinary tract infection. previously, we reported that preinoculating urinary catheters with a nonpathogenic strain of escherichia coli (83972) significantly impeded catheter colonization in vitro by gram-positive bacteria (enterococcus faecalis). to explore this phenomenon further, we investigated in vitro whether e. coli 83972 could likewise inhibit cath ...	2003	12736047
[purple urine bag syndrome].	the report of purple discoloration in a urinary drainage system, known as purple urine bag syndrome (p.u.b.s.) is rarely described in the literature.	2003	12876527
extended-spectrum beta-lactamases in enterobacteriaceae in buenos aires, argentina, public hospitals.	resistance to extended-spectrum cephalosporins is often associated with plasmid encoded extended spectrum beta-lactamases (esbl). in order to evaluate the prevalence and diversity of esbls in enterobacteria in our city, a 1-month-period survey was carried out from april to may 2000. extended-spectrum-cephalosporin-resistant strains, isolated from inpatient clinical specimens other than stools, were collected among 17 participating hospitals. from a total of 427 enterobacterial strains that were ...	2003	12936986
gasp phenotype: presence in enterobacteria and independence of sigmas in its acquisition.	the appearance of growth advantage in stationary phase or gasp was originally detected in escherichia coli. the presence of this phenotype in other enterobacteria such as enterobacter cloacae, salmonella typhimurium, providencia stuartii and shigella dysenteriae is described in this work. e. cloacae gasp strains presented lower levels of rpos than the parental strain, although no mutation in the gene or its promoter was detected. this work offers evidence of gasp rpos-independent pathways as gas ...	2003	12951242
indole can act as an extracellular signal to regulate biofilm formation of escherichia coli and other indole-producing bacteria.	we demonstrated previously that genetic inactivation of tryptophanase is responsible for a dramatic decrease in biofilm formation in the laboratory strain escherichia coli s17-1. in the present study, we tested whether the biochemical inhibition of tryptophanase, with the competitive inhibitor oxindolyl-l-alanine, could affect polystyrene colonization by e. coli and other indole-producing bacteria. oxindolyl-l-alanine inhibits, in a dose-dependent manner, indole production and biofilm formation ...	2003	14569285
extended-spectrum beta-lactamase-producing enterobacteriaceae in community and private health care centers.	in 1999, 39 of 2,599 isolates of the family enterobacteriaceae (1.5%) collected by eight private laboratories in the aquitaine region in france produced an extended-spectrum beta-lactamase (esbl). among these were 19 enterobacter aerogenes isolates; 8 klebsiella pneumoniae isolates; 6 escherichia coli isolates; 3 proteus mirabilis isolates; and 1 isolate each of serratia marcescens, morganella morganii, and providencia stuartii. esbl producers were isolated from 38 patients, including 33 residen ...	2003	14576109