Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| the role of campylobacter pylori in the pathogenesis of peptic ulcer disease. | most patients with peptic ulceration have chronic gastritis, which typically involves predominantly the antrum. the association between campylobacter pylori-associated gastritis and peptic ulceration has recently been repeatedly demonstrated. evidence is accumulating that the bacterium plays a causal role in type-b chronic gastritis. c. pylori also colonizes the duodenum when gastric metaplasia is present. it is likely that the inflamed mucosa is more susceptible to ulcerogenic influences affect ... | 1989 | 2665051 |
| campylobacter pylori and non-ulcer dyspepsia. 1. the final results of a double-blind multicentre trial for treatment with pirenzepine in italy. | in a double-blind multicentre trial to study the effect of pirenzepine in the treatment of non-ulcer dyspepsia, 104 of 128 patients, 52 in each of the study and control groups, completed the 4 weeks of the investigation. there was improvement of the endoscopic and clinical findings but no change of the degree of the mucosal inflammation or the extent of colonisation by campylobacter pylori. the mode of action of pirenzepine in patients with non-ulcer dyspepsia associated with campylobacter relat ... | 1989 | 2694330 |
| [non-ulcer dyspepsia and campylobacter pylori]. | dyspepsia, defined as chronic vague upper abdominal symptoms, is a common condition. the pathogenesis of this syndrome remains poorly understood. the etiologic role of campylobacter pylori and associated gastritis remain controversial though this organism colonizes the gastric antrum in one third to one half of patients with non-ulcer dyspepsia. recent studies raise the prospect that treatment with bismuth improves gastritis and is successful in treating symptoms in the campylobacter pylori posi ... | 1989 | 2667070 |
| successful lyophilization of campylobacter pylori and spiral organisms from the stomachs of animals. | 1989 | 2696921 | |
| [characteristics of the endoscopic diagnosis of peptic ulcer and chronic gastritis associated with campylobacter pylori]. | 1989 | 2699098 | |
| proteolytic activities of human campylobacter pylori and ferret gastric campylobacter-like organism. | the levels of proteolytic activity in cell washes, lysates and pellets of c. pylori and gastric campylobacter-like organisms isolated from humans and ferrets, respectively, have been studied using porcine mucus glycoprotein and bovine haemoglobin substrates. the total haemoglobin degrading activity, expressed by 10(12)-10(13) cfu of either organism, was no greater than 3 micrograms chymotrypsin equivalents. the mucolytic specific activity (rate of mucus peptide bond hydrolysis by bacterial prote ... | 1989 | 2673233 |
| [campylobacter pylori gastritis: review of diagnostic methods]. | the presence of campylobacter pylori in gastric mucosa is a proof of active gastritis. diagnostic methods are based on endoscopy: culture--histology--cytology--urease test, or on noninvasive tests: c14 urea breath test and serology. the principles, results (sensitivity--specificity), advantages and problems of each test are discussed as well as the choice of a diagnostic method. in practice, we recommend the use of two methods, a morphological one (histology or cytology) and another based on bac ... | 1989 | 2700272 |
| campylobacter pylori as possible factor in peptic ulcer recurrence. | the author reviews the literature up to 1988 about the close association of campylobacter pylori with chronic active gastritis, duodenitis and peptic ulcer disease. no firm data however demonstrate that campylobacter pylori causes duodenal ulcer but long term eradication of this bacterium prevents duodenal ulcer relapse. | 1989 | 2700273 |
| [personal experience with isolation of campylobacter pylori from the gastroduodenal mucosa]. | during the period between march 1987 and july 1988 the authors examined for the presence of campylobacter pylori bioptic specimens from the gastroduodenum from 410 patients. in the above group they diagnosed by microscopic examination c. pylori in 257 patients (mean 63%). from the whole group 282 patients (100%) were examined concurrently by the microscopic method and by cultivation. this number comprised 195 (68.9%) who were positive on microscopic examination and 110 (42.2%) who were positive ... | 1989 | 2676200 |
| can gastritis symptoms be evaluated in clinical trials? an overview of treatment of gastritis, nonulcer dyspepsia and campylobacter-associated gastritis. | we carried out a review of the literature on campylobacter pylori-associated gastritis and nonulcer dyspepsia (nud) to determine whether or not symptoms related to these conditions can be measured reliably and whether or not any study to date has shown that treatment alters symptoms. search strategies consisted of online medline searching, a forward search of three articles using the science citation index, a manual search of five gastroenterological journals, and a fully recursive search of cit ... | 1989 | 2677123 |
| [intragastric formation of ammonia in campylobacter pylori associated gastritis. diagnostic and pathogenetic significance]. | the diagnostic relevance of measurement of ammonia (nh3) in not stimulated gastric juice in patients with campylobacter pylori associated gastritis (cpag) is in discussion. the role of cp-urease induced nh3 in pathogenesis of active gastritis is unclear. in answering to this questions we evaluated the sensitivity and specifity of nh3-test and clo-test in cases of cpag (n = 50), non cpag (n = 16) and normal gastric mucosa (n = 20). we found a 88% sensitivity and a 86% specifity for nh3-test, a se ... | 1989 | 2677629 |
| [significance of campylobacter pylori in gastritis, non-ulcer dyspepsia and ulcer. a critical observation]. | 1989 | 2677634 | |
| [campylobacter pylori compels re-thinking]. | 1989 | 2709948 | |
| [campylobacter pylori and gastritis--the density of colonization and degree of inflammation. a semiquantitative and morphometric study]. | gastric biopsies of 1000 patients were grouped according to their diagnoses, special interest was devoted to type b-gastritis. density of campylobacter pylori colonization was determined semiquantitatively after warthin-starry silver impregnation. bacteria could never be seen in normal mucosa. in b-gastritis statistics proved a significant correlation between bacterial colonization density and degree of inflammation. in 60 selected cases this close interrelation could be objectified by morphomet ... | 1989 | 2709949 |
| [a rapid urease test in campylobacter pylori colonization of the gastric mucosa]. | biopsies from the gastric mucosa (antrum, corpus) of 145 patients investigated by endoscopy were analysed for campylobacter pylori. the results of bacteriological, histological, enzymatic and chemical methods were compared. urease activity was determined both in biopsies (clo-test) and in gastric secretion. furthermore, the concentration of urea was measured in gastric secretion. 71% of gastritis, 86% of ulcus duodeni and 83% of ulcus ventriculi diagnosed by endoscopy produced positive histologi ... | 1989 | 2679659 |
| comparative in vitro activities of six new fluoroquinolones and other oral antimicrobial agents against campylobacter pylori. | the in vitro susceptibilities of 56 clinical isolates of campylobacter pylori to six new fluoroquinolones and other oral antimicrobial agents were determined by an agar dilution technique. ciprofloxacin was the most active of the fluoroquinolones (mic for 90% of strains tested [mic90], 0.05 microgram/ml). other fluoroquinolones had variable activities, although most isolates were moderately susceptible to fleroxacin (mic90, 4 micrograms/ml) and lomefloxacin (mic90, 4 micrograms/ml). | 1989 | 2712542 |
| nonsecretors and peptic ulceration. no link with campylobacter pylori. | 1989 | 2714155 | |
| [advances in research on campylobacter pylori]. | 1989 | 2679984 | |
| campylobacter associated gastritis in patients with non-ulcer dyspepsia: a double blind placebo controlled trial with colloidal bismuth subcitrate. | fifty consecutive patients with non-ulcer dyspepsia and a campylobacter associated gastritis (cag) were randomly assigned to treatment with colloidal bismuth subcitrate (cbs) 240 mg twice daily or placebo, according to a double blind study design. after the blind treatment an 'open' treatment with cbs was started in both groups. twenty six patients treated with cbs showed a significant reduction in colonisation with campylobacter pylori and a significant improvement in the whitehead gastritis sc ... | 1989 | 2680795 |
| [bismuth aluminate in gastroenterology. therapeutic effects in chronic erosive campylobacter pylori-associated gastritis]. | 14 patients with epigastric pain and chronic active gastritis as well as endoscopically proven erosions underwent an open therapeutic trial with bismuth aluminate (3 x 300 mg/day) for three weeks. prior to and after treatment five biopsy specimens were taken from the antral mucosa 2 and 4 cm proximal to the pylorus for histological scoring of inflammatory activity and c. pylori detection, for urease quick test (cut) and culture. before treatment c. pylori was detected histologically and by cut i ... | 1989 | 2680842 |
| [diagnosis and treatment of gastric campylobacteriosis in patients with peptic ulcer and chronic gastritis]. | the endoscopic picture of peptic ulcer was studied in 104 patients; the gastric mucosa of 30 per cent of the patients was infected with campylobacter pyloridis (cp) and had acute erosions in the pyloroduodenal zone. erosions in uninfected patients were found in 3 per cent of the cases. the predominant lymphoid infiltration of the mucous coat of the stomach was revealed in 60 ulcer patients irrespective of the cp infection. mucous infiltration with polymorphonuclear leukocytes was found in 13 chr ... | 1989 | 2716260 |
| isolation of a campylobacter-like organism from healthy syrian hamsters (mesocricetus auratus). | a campylobacter-like organism was isolated from the ilea of normal hamsters. the organism was isolated from an ileal homogenate which was passed through a filter (0.65-micron pore size) and cultured on blood-agar plates in a microaerophilic atmosphere at 37 degrees c. pinpoint translucent colonies were first observed after 120 h of incubation. the isolated organism measured 2.0 to 3.5 microns in length (excluding flagella) by 0.17 to 0.25 micron in width and typically had a single terminal sheat ... | 1989 | 2681250 |
| campylobacter pylori and large gastric folds. | 1989 | 2717728 | |
| campylobacter pylori. diagnosis and treatment. | there is now a plethora of methods to diagnose colonization of the human stomach with campylobacter pylori, such as microbiological culture on various media, identification of c. pylori in biopsies or biopsy smears using various stains or neurological methods, serological demonstration of specific anti-c. pylori antibodies, measuring urease activity with one of the many urease tests or using the 13c- or 14c-urea breath test. therapy should be directed at permanent eradication of the organism. er ... | 1989 | 2681390 |
| [experience with the treatment of duodenal ulcer associated with campylobacter pylori infection by combined use of anti-secretory and antibacterial drugs]. | 1989 | 2681993 | |
| [analysis of the prevalence of anti-campylobacter pylori antibodies detected in a healthy human population]. | a study was made of the prevalence of anti c. pylori in the healthy adult population. the analytical method used was indirect immunofluorescence. an analysis was made of 231 sera (122 males and 109 females) from subjects 20 to 82 years-old. the global positivity detected was 21.1%. there was a slight rise in the percentage of positivities as age increased, reaching the maximum rate in the group over 50 years (2.1%). the titers detected were low and unrelated to age. no significant differences by ... | 1989 | 2682831 |
| [campylobacter pylori, its endoscopic detection in childhood]. | 1989 | 2720817 | |
| two-dimensional gel electrophoresis and immunoblotting of campylobacter pylori proteins. | whole-cell, outer-membrane protein, flagellum-associated antigens and partially purified urease of campylobacter pylori were analyzed by two-dimensional gel electrophoresis. c. pylori strains were readily distinguished from strains of campylobacter jejuni, c. coli, and c. fetus by absence of major outer membrane proteins with mrs of 41,000 to 45,000. c. pylori strains also lacked the acidic surface-array proteins at mr 100,000 to 149,000 identified previously in serum-resistant strains of c. fet ... | 1989 | 2722241 |
| [incidence, intensity and clinical manifestations of antral gastritis in duodenal ulcer in women and their relation to campylobacter pylori]. | it was established during examination of 120 women with duodenal ulcer that in 48 percent of them the clinical disease manifestations were typical. in patients with an atypical disease course, the painful syndrome was not pronounced. it was not dependent on food intake or season. 34.2 percent of the patients had, instead of pains, a feeling of heaviness in the epigastric area, heartburn and eructation depending on the antral gastritis severity. the ulcers measured 5 mm and less in 75.6 percent o ... | 1989 | 2727917 |
| duodenal ulcer disease: what role does campylobacter pylori play? | duodenal ulcer is a chronic relapsing condition which only became common early this century. many pathogenic factors have been identified including excess gastric acid secretion, cigarette smoking, non-steroidal anti-inflammatory drugs and reduced mucosal defence. there is a strong association of duodenal ulceration, gastric campylobacter pylori and antral (type-b) gastritis. the link between ulceration in the duodenum and c. pylori-associated antral gastritis may lie in the formation of gastric ... | 1989 | 2683020 |
| pathogenicity of campylobacter pylori--a causative factor in gastritis? | there is now much worldwide evidence that campylobacter pylori plays a pathogenic role in the aetiology of gastritis rather than colonizing an already inflamed gastric mucosa. 1) there is a very close association between the presence of c. pylori on the gastric mucosa and histologically confirmed type b chronic active gastritis. ninety percent of patients with c. pylori infection have gastritis whereas less than 5% of patients with normal mucosa are colonized. 2) c. pylori only colonizes gastric ... | 1989 | 2683021 |
| campylobacter pylori--therapy review. | although campylobacter pylori is sensitive to many antibiotics in vitro, few are effective in vivo. furthermore, treatment regimens which successfully clear the organism in vivo are associated with high recurrence rates when assessed one month following treatment. on the other hand, 85% of those individuals who are c. pylori negative 1 month after the cessation of therapy remain negative at 12 months and the infection can be considered to be eradicated. treatment with certain bismuth salts appea ... | 1989 | 2683022 |
| campylobacter pylori and ulcer disease--a causal connection? | a strong positive correlation has been demonstrated between the (antral mucosal) presence of campylobacter pylori and active duodenal and gastric ulceration. moreover, both duodenal and gastric ulcers heal, and remain in remission, as a consequence of therapeutic measures which eradicate c. pylori. however, the henle-koch postulates have not been fulfilled, because c. pylori has not been shown to produce ulcers. as for the claim that ulcer disease represents an infection with c. pylori because t ... | 1989 | 2683023 |
| prevalence of campylobacter pylori in esophagitis, gastritis, and duodenal disease. | the relationship between the presence of campylobacter pylori and esophagitis was studied in patients undergoing paired biopsies of distal esophagus and gastric antrum during esophagogastroduodenoscopy. biopsy specimens were examined for urease activity and for the presence of c pylori by culture and by histologic examination of hematoxylin-eosin- and warthin-starry-stained sections. sixty-two patients were entered into the study. all esophageal biopsy specimens, regardless of histologic finding ... | 1989 | 2730254 |
| campylobacter pylori--a role in non-ulcer dyspepsia? | non-ulcer dyspepsia (nud) is a common complaint in which no systematic illness or organic proximal alimentary tract disease can be identified. the pathophysiology of nud is probably heterogeneous. eighty-two subjects with nud were studied in a prospective randomized placebo-controlled study to assess the efficacy of colloidal bismuth subcitrate (cbs) chewable tablets at a dose of four tablets daily for 1 month. the role of campylobacter pylori and associated histological gastritis was evaluated. ... | 1989 | 2683024 |
| minitek urea disk test, a sensitive and cost-effective method to screen for campylobacter pylori in gastric biopsies. | one hundred fifty-five biopsy specimens from the gastric mucosa of 81 patients undergoing routine endoscopy procedures were tested for the presence of campylobacter pylori by three methods: gram stain, culture, and modified minitek, a rapid urea disk test (bbl microbiology systems, cockeysville, md.). twenty-nine patients were infected with c. pylori. sensitivities and specificities of detection were 100 and 94% with the minitek test and 93 and 100% with gram stain, respectively. rapid testing b ... | 1989 | 2687317 |
| [antibacterial treatment of campylobacter pylori-associated gastritis and peptic ulcer]. | on the basis of possible etiological or pathogenetic significance of campylobacter pylori for the development, maintenane og recurrence of gastritis and peptic ulceration, a review based on the literature is presented for the sensitivity of the bacteria in vitro and in vivo to antibiotics and preparations employed in the medicinal treatment of gastritis and peptic ulceration. the bacterium is sensitive in vitro to a long series of antibiotics and all of the anti-ulcer agents have, similarly, ant ... | 1989 | 2734863 |
| recurrence of duodenal ulcer and campylobacter pylori infection after eradication. | the role of campylobacter pylori gastritis in dyspepsia could be clarified more readily if reliable eradication therapy were available. antibiotic monotherapy and combined therapy with an antibiotic agent plus a bismuth compound have yielded poor long-term results. in this study, bismuth-tetracycline-metronidazole triple therapy has been used to eradicate c. pylori infection in 100 consecutive patients who were suffering from either a duodenal ulcer or non-ulcer dyspepsia. examination of a follo ... | 1989 | 2687668 |
| is antibacterial therapy against campylobacter pylori useful in the treatment of indigestion and chronic peptic ulceration? | campylobacter pylori is a spiral gram-negative rod that was first identified in human gastric mucosa in 1906. since 1983, interest in the organism has been renewed; it was first cultured, and has since been found to be very strongly associated with the histologic presence of antral gastritis. further, it has been suggested that this organism may play a role in peptic ulceration. c. pylori is sensitive to many different antibiotics as well as to bismuth. however, recrudescence of infection after ... | 1989 | 2688215 |
| no acid, no polys--no "active" gastritis, no dyspepsia. a proposal. | the current dilemma in characterizing non-ulcer dyspepsia (nud) is due to the very nature of the term which has forced the dependence for diagnosis primarily on symptomatology and the absence of an ulcer crater as ascertained by radiographs or endoscopy. i propose a new classification which i believe is consistent and well founded, based on the presence of histologic gastritis and acid secretion of the stomach. four categories are presented: (a) normal histology, (b) "active" gastritis, (c) "ina ... | 1989 | 2738355 |
| campylobacter pylori and trials of ulcer recurrence. | 1989 | 2738364 | |
| pediatric upper gastrointestinal endoscopy: a 13-year experience. | this report describes a series of 553 flexible upper gastrointestinal (gi) endoscopies performed on 382 children in two surgical centers between 1975 and 1987. indications included abdominal pain (180), reassessment of known disease (149), upper gi bleeding (99), foreign body ingestion (77), vomiting (14), dysphagia (10), and miscellaneous (24). findings were chronic peptic ulcer (47), gastritis/duodenitis (63), healing disease (92), nonhealing disease (22), recurrent disease (32), foreign body ... | 1989 | 2738808 |
| [has campylobacter pylori infection any clinical relevance? methodologic, epidemiologic and clinical studies]. | the occurrence of campylobacter pylori (cp) was studied in 180 patients referred for endoscopy. the bacterium was detected by culture, histology (warthin-starry staining) and urease test of antral biopsy samples. patient groups were formed according to endoscopic diagnoses, clinical symptoms and antral mucosal histology. 50 cp positive patients with chronic antral gastritis were treated by bismuth subsalicylate (2,4 g/day) for 3 weeks. positivity by culture and/or silver-stained histology proved ... | 1989 | 2689946 |
| [clinical importance of campylobacter pylori. second part]. | 1989 | 2694295 | |
| [pathogenetic properties of campylobacter pylori]. | 1989 | 2696836 | |
| campylobacter pylori detection by rapid urease test. | 1989 | 2699989 | |
| [campylobacter pylori in diseases of the stomach and duodenum]. | campylobacter pylori is an organism living under mucus layer in the stomach and on the places of gastric mucosa metaplasia. it is known to be responsible for the development of gastritis, probably also it participates in the pathogenesis of dyspepsia without ulcer, while its role in the development of gastric and duodenal ulcer has not yet been explained completely. the authors present a characteristics of the organism and the methods of its detection. a number of investigations are discussed wh ... | 1989 | 2701041 |
| [the microbiological diagnosis of chronic gastropathy associated with campylobacter pylori]. | the efficiency was studied, in experimental and practical conditions, of media for the isolation of c. pylori, as well as criteria for diagnosis and identification. the highest sensitivity was obtained with columbia gelose, and a lower sensitivity was achieved with campy i. c. gelose, and with heart-brain gelose, prepared as chocolate gelose, and columbia gelose with integral blood. both variants of the mueller-hinton gelose, even in the chocolate formula, gave negative results. of the fluid med ... | 1989 | 2701344 |
| [what should surgeons know about campylobacter pylori?]. | 1989 | 2704282 | |
| [epidemiology and therapy of campylobacter pylori infection]. | the prevalence of campylobacter pylori in gastric mucosa was investigated prospectively (by histology, cytology, bacterial culture and urease rapid-test) in 302 patients of a routine gastroenterological endoscopy programme. according to the histopathological findings the following prevalence of c. pylori was established: 3 of 35 normals (9%); 116 of 167 with antral gastritis (69%), 28 of 40 with gastric ulcers (70%); 26 of 33 with duodenal ulcers (79%); 5 of 27 with other conditions (19%). the a ... | 1989 | 2707124 |
| [clinico-endoscopic characteristics and laboratory diagnosis of chronic campylobacter gastritis in childhood]. | altogether 31 children with chronic gastritis were examined. three diagnostic tests were employed for detecting campylobacter pylori. the clinical signs of the disease and the endoscopic features of the gastric mucosa are described. | 1989 | 2710607 |
| rapidly decreased serum igg to campylobacter pylori following elimination of campylobacter in histological chronic biopsy campylobacter-positive gastritis. | the anaerobic bacterium campylobacter pylori (cp) is thought to be associated with chronic gastritis. this paper presents clinical data underpinning this view. five patients with histological chronic gastritis as determined by diagnostic endoscopy, which was associated with cp as determined by positive biopsy cultures, all possessed statistically raised serum igg elisa titers to cp during a longitudinal period of observation of 15 months. treatment with the antibiotics amoxycillin (clamoxyl) or ... | 1989 | 2714840 |
| [clinical, endoscopic and histologic findings in 1,100 patients of whom 574 were colonized by campylobacter pylori]. | of 1,100 patients checked by at least two diagnostic tests (urease, histology, culture) 574 (52.1 p. 100) were found to have campylobacter pylori (c. pylori) in their antral mucosa. significantly different frequencies of c. pylori (p less than 0.005) were evidenced in the group of patients with active gastroduodenal ulcer (212/298, 71 p. 100), in non-ulcer dyspepsia (nud) with a previous history of gd ulcer (108/177, 61 p. 100) and nud without antecedent history of gd ulcer (254/625, 41 p. 100). ... | 1989 | 2744327 |
| cellular fatty acid composition of campylobacter pylori from primates and ferrets compared with those of other campylobacters. | the cellular fatty acid profiles of newly described campylobacters were determined on a polar, capillary column. six isolates of the gastric spiral organism, campylobacter pylori subsp. mustelae, from ferrets from australia, england, and the united states were all found to have a similar fatty acid profile which was different from that of c. pylori from humans; c. pylori subsp. mustelae did not have 3-hydroxyoctadecanoic acid (3-oh c18:0) and had much less tetradecanoic acid (c14:0) and much mor ... | 1989 | 2745703 |
| ultrastructure and chemical analysis of campylobacter pylori flagella. | flagella of campylobacter pylori were analyzed by electron microscopy and purified, and the molecular weight of the flagellin was determined. isolation of flagella was performed by mechanical shearing from the cell surface, sucrose density gradient centrifugation, and sepharose cl-4b gel chromatography. the flagella of c. pylori differ from those of other campylobacter species and of most other bacteria by the presence of a flagellar sheath. the sheath narrows at the end and is linked to a club- ... | 1989 | 2715319 |
| gastric metaplasia and campylobacter pylori infection of duodenum in patients with chronic renal failure. | duodenal biopsy specimens from 80 patients with chronic renal failure, who were undergoing haemodialysis, were examined by light microscopy for evidence of inflammation, gastric metaplasia, and campylobacter pylori infection. chronic duodenitis was present in 47 (59%) of patients, of whom only seven (9%) showed evidence of active inflammation. gastric metaplasia was present in 50 (62.5%) of patients, yet campylobacter pylori was identified in only two patients (2.5%). it is suggested that the du ... | 1989 | 2715348 |
| campylobacter pylori in patients undergoing gastroscopy at goroka base hospital. | biopsy specimens were taken from intact areas of antral mucosa in 53 consecutive highlanders presenting for gastroscopy. spiral or curved bacilli were demonstrated in 31 patients (58%). campylobacter pylori was cultured from 17 patients (32%). the bacteria were present in 16 (76%) of the 21 patients with gastric ulcer. histological studies carried out in 25 patients showed gastritis in 21 (84%) and the bacteria were present in all 8 cases of active chronic gastritis and in 5 of 13 cases (38%) of ... | 1989 | 2750318 |
| [the effect of a calcium carbonate-bismuth subsalicylate combination on intragastric acidity over the course of 24 hours. a randomized study of healthy probands]. | bismuth salts are successfully used for the treatment of campylobacter-pylori-associated gastritis. it cannot be excluded, however, that calcium carbonate, which is present in one of the recommended preparations (calcium carbonate/bismuth subsalicylate, jatrox), may have an additional therapeutic effect due to an increase of intragastric ph. therefore, the in-vitro h+ buffering capacity of jatrox was determined in comparison to other antacids using the ph-stat technique, and its effect on intrag ... | 1989 | 2716711 |
| enlarged gastric folds in association with campylobacter pylori gastritis. | enlarged gastric folds in pediatric patients are uncommon. fifteen patients with upper gastrointestinal (gi) tract symptoms of chronic epigastric abdominal pain, vomiting, or hematemesis underwent radiologic upper gi barium studies and were found to have campylobacter pylori gastritis at endoscopic biopsy. seven patients (47%) with c pylori gastric disease had radiologic evidence of enlarged folds. there was no clinical or pathologic evidence of ménétrier disease. therefore, c pylori gastritis s ... | 1989 | 2717759 |
| patterns of physical modes of contact between campylobacter pylori and gastric epithelium: implications about the bacterial pathogenicity. | since the exact mechanisms of the pathogenicity of campylobacter pylori are not known, we performed an ultrastructural study with the aim of focusing on patterns of possible physical contact between c. pylori and gastric epithelium, and of considering them in relation to the bacterial pathogenicity. among 20 random consecutive patients referred for routine gastroscopy, we studied ultrathin sections from the 11 patients with campylobacter-like organisms, and recognized three patterns of physical ... | 1989 | 2719007 |
| the effect of cooling rate, freeze-drying suspending fluid and culture age on the preservation of campylobacter pylori. | the effects of freezing rate, suspending fluid and age of culture on the ability of four strains of campylobacter pylori to survive and recover from freeze-drying were examined. freeze-drying by standard procedures generally resulted in an overall loss in viability of between 3 and 7 log units. the exact cause of poor recovery by c. pylori was not established but strain differences were detected, with nctc 11637 (type strain) surviving better than nctc 11638 and nctc 11639. recovery of the poore ... | 1989 | 2753837 |
| examination of human stomach biopsies, saliva, and dental plaque for campylobacter pylori. | to examine possible sources of campylobacter pylori and to determine the routes by which it is transmitted to the human stomach, samples of dental plaque and saliva from 71 patients undergoing endoscopy in addition to stomach biopsies were collected and cultured on selective noninhibitory skirrow medium. a total of 29 (40.8%) of the stomach biopsies yielded c. pylori. none of the saliva samples and only one of the dental plaque samples was found positive for c. pylori, and thus neither saliva no ... | 1989 | 2754008 |
| treatment failure of norfloxacin against campylobacter pylori and chronic gastritis in patients with nonulcerative dyspepsia. | several reports have been published to show the in vitro susceptibility of campylobacter pylori to different classes of antibiotics, including fluoroquinolones. the purpose of this study was to describe the clinical effect of norfloxacin on eradication of c. pylori in patients with gastritis. endoscopy was performed in 38 patients with symptoms of nonulcerative dyspepsia. of these, 20 patients had a c. pylori-positive culture. from this group, 17 patients were treated with norfloxacin for 1 mont ... | 1989 | 2719469 |
| [campylobacter pylori in chronic gastritis]. | altogether 301 patients with duodenal, gastric and prepyloric ulcers and non-ulcer controls were examined to study whether the campylobacter pylori is related to ulcer itself or to coexisting chronic gastritis. histological sections from antral and body mucosa were stained according to warthin-starry, giemsa and with hematoxylin-eosin. the campylobacter pylori was strongly associated with chronic superficial gastritis in both ulcer and non-ulcer patients and in both antral and body mucosa. no di ... | 1989 | 2727918 |
| prevalence of campylobacter pylori in patients undergoing upper endoscopy. | from august 1987 through july 1988, we evaluated antral biopsy specimens for campylobacter pylori (cp) in 212 patients undergoing upper endoscopy. for those patients who had multiple endoscopies, the first endoscopy in which a urease test, histology, and culture were done was used to determine cp status. a patient was regarded as cp-positive if the culture was positive or if both a urease test and the histology were positive. blacks had an increased cp positivity (61.2%) compared to whites (31.5 ... | 1989 | 2729234 |
| campylobacter pylori in patients with dyspeptic symptoms and endoscopic evidence of erosion(s). | the relationship between campylobacter pylori (cp), histologic gastritis, and dyspeptic symptoms is becoming gradually clearer, but there is still a lack of knowledge of the natural history of treated or untreated gastritis. we examined serial biopsies from the gastric fundus, body, and antrum, and from the duodenum in 16 dyspeptic patients. patients with concomitant peptic ulcers, alcoholism, or nonsteroidal anti-inflammatory drug use were excluded. cp was present in the biopsies of 50% of pati ... | 1989 | 2729235 |
| [diagnosis of gastritis caused by campylobacter pylori. presentation of 3 methods: bacteriology, histology and immunoblotting]. | 1989 | 2756576 | |
| campylobacter pylori: "all that glitters is not gold". | 1989 | 2729249 | |
| [histologic study of campylobacter pylori: role of fixation]. | 1989 | 2731687 | |
| [campylobacter pyloridis in duodenal ulcer]. | a morphologic study of antral gastric and duodenal mucosa was carried out in patients with duodenal ulcers. peptic ulcers were in the phase of exacerbation in 55 patients, and that of remission, in 10. campylobacter pyloridis (cp) were detected in 83% of the cases by histologic investigation of gastric and duodenal mucosa biopsy specimens obtained from patients with duodenal ulcers. cp were more common and numerous during exacerbation rather than remission of peptic ulcers. bacterial disseminati ... | 1989 | 2734670 |
| [gastritis and ulcer: reconsidering therapy? report from a presymposium: "campylobacter pylori--value of therapy today". 3 march 1989, taormina/sicily. abstracts]. | 1989 | 2737588 | |
| new spiral bacterium in gastric mucosa. | a new spiral bacterium, distinct from campylobacter pylori, was found in the gastric mucosa of six patients with gastrointestinal symptoms. all patients had chronic active type b gastritis and four had oesophagitis. culture and microscopy for c pylori infection was negative. these unculturable spiral organisms were probably an incidental finding in patients presenting for upper gastrointestinal endoscopy, but it is not possible to say from this small series whether these organisms cause chronic ... | 1989 | 2738164 |
| scanning electron microscopy in the study of campylobacter pylori associated gastritis. | the close association between campylobacter pylori (cp), gastritis and peptic ulcer is now well established. moreover increasing evidence has been collected of a major etiological role of cp in type b chronic gastritis. for this reason, searching for cp is essential in all patients with upper gastrointestinal symptoms. scanning electron microscopy (sem) is a most reliable technique for studying the distribution of microorganisms and their relationship to the gastric mucosal surface. the aim of t ... | 1989 | 2740873 |
| [campylobacter pylori: clinical correlations and prospective comparative studies of various diagnostic techniques]. | the diagnostic performance of two different urease tests and of histologic search after modified giemsa staining to detect campylobacter pylori (cp) colonization of the upper gastrointestinal tract was prospectively investigated in 215 esophagogastroduodenoscopies, by using a sensitive culture technique as reference. single antral urease tests had a high specificity of 95-96%, but a limited sensitivity of 78-83%, which increased to 91-94%, when one antral and one additional body biopsy were subm ... | 1989 | 2759652 |
| evaluation of three campylobacter pylori antigen preparations for screening sera from patients undergoing endoscopy. | a surface antigen (sa), acid glycine extract (age), and urease preparation (up) were evaluated using sera from patients undergoing endoscopy and from subjects with gastric or duodenal ulcers. sera were tested for the presence of igg and iga antibodies by a conventional indirect enzyme linked immunosorbent assay (elisa). in patients with confirmed campylobacter pylori associated gastritis, raised igg antibody titres were indicated by absorbance values of greater than or equal to 500, greater than ... | 1989 | 2760233 |
| the upper gastrointestinal microflora in relation to gastric diseases and gastric surgery. | the upper gastrointestinal microflora was evaluated in relation to gastric diseases and gastric surgery. postoperative septic complications and microorganisms found in primary infections were studied in 750 gastric operations. the overall rate of primary infections was 23%. enterobacteriaceae, enterococci and bacteroides fragilis were more frequently found in postoperative infections in patients with gastric bleeding or carcinoma. the microbial colonization of the oropharynx, esophagus and stoma ... | 1989 | 2741634 |
| campylobacter pylori-associated gastritis and immune response in a population at increased risk of gastric carcinoma. | a series of 169 consecutive patients from low socioeconomic strata attending the gastroenterology clinic of charity hospital in new orleans were evaluated clinically and endoscopically. this general new orleans population is known to be at increased risk of developing gastric carcinoma. the type of gastritis was identified histologically, and the presence of campylobacter pylori was determined by culture and/or histology. the overall prevalence of c. pylori infection in this patient population w ... | 1989 | 2741887 |
| urease tests for campylobacter pylori detection. | 1989 | 2741898 | |
| relationship of campylobacter pylori and duodenogastric reflux. | we have examined the relationship of campylobacter-like organism (clo) and duodenogastric reflux (dgr) in 107 patients with unoperated stomachs. neither the extent of externally measured bile reflux nor the concentrations of bile acids or lysolecithin in the gastric fluid differed significantly in the groups with different numbers of clo in the gastric mucosa. our results suggest that dgr, in the quantities commonly present in unoperated stomachs, does not effect the presence of c. pylori in the ... | 1989 | 2743841 |
| antigens for the serodiagnosis of campylobacter pylori infections. | 1989 | 2744322 | |
| [campylobacter pylori in patients with chronic gastritis and gastric and duodenal peptic ulcer]. | the presence of campylobacter pylori was studied in biopsy material from gastric mucosa taken by guided biopsy during fiber gastroduodenoscopy from 101 patients with chronic gastritis (n = 50), peptic gastric ulcer (n = 28), peptic duodenal ulcer (n = 7), gastric cancer (n = 10) and gastric polyposis (n = 6). campylobacter pylori was found in various quantity--moderate (++) and considerable ( )--in 64% of the patients with chronic gastritis, in 85.7% of the patients with peptic gastric ulcer and ... | 1989 | 2763525 |
| gastritis and campylobacter pylori. | 1989 | 2764663 | |
| non campylobacter pylori spiral organisms in the gastric antrum. | colonisation of the human gastric antrum with non campylobacter pylori spiral organisms is described. a moderately severe histological gastritis was present despite the fact that these organisms, in contrast to c. pylori, were not closely associated with the epithelial cell surface. although in vitro culture of the organisms was unsuccessful, in vivo culture was achieved in the mouse stomach. further study of these spiral organisms should provide important clues to the role of bacteria in upper ... | 1989 | 2764819 |
| [molecular markers and identification of campylobacter pylori strains]. | campylobacter pylori was studied to define the classification of species and the typing of strains. the mol p. 100 g + c of 17 strains ranged from 34.1 to 37.5 (average value: 35.2; sd: 1.0). the strains are closely related (80 to 100 p. 100 dna/dna relatedness) and to the type strain nctc 11367. the endonuclease restriction profiles were specific of strains. dna analysis (rea) is a sensitive method in pathogenic and epidemiological studies. | 1989 | 2744323 |
| [campylobacter pylori and gastroduodenal pathology. symposium. bordeaux, 7-8 october 1988]. | 1989 | 2744324 | |
| [scanning electron microscopic study of campylobacter pylori and associated gastroduodenal lesions]. | the detection of campylobacter pylori was carried out with scanning electron microscopy (sem) on 4,590 biopsies taken from 1,714 adult patients (1,348 duodenal biopsies, 1,690 antral biopsies and 1,552 fundic biopsies). the mucus was removed and the fragments of mucosa were then fixed with glutaraldehyde, dehydrated, critical point-dried with co2 or hexamethyldisilazane, mounted, coated with gold, and observed with sem. under sem, c. pylori was characterized by its spiral-shape (long form 2.5 to ... | 1989 | 2744325 |
| long-term storage of campylobacter pylori. | a reproducible method for long-term storage of campylobacter pylori has been previously described. we cultured 10 strains of c. pylori in brucella broth that was supplemented with 10% fetal bovine serum. after incubation for 24 h, 10% glycerol and an additional 10% fetal bovine serum were added to the cultures, which when then held in storage at -70 degrees c. after 6 months, each of the strains remained viable. this technique, therefore, represents an excellent method for long-term storage of c ... | 1989 | 2768452 |
| improved growth of campylobacter pylori in a biphasic system. | the recovery of campylobacter pylori from clinical specimens is difficult, even when done with an optimal medium, atmosphere, and temperature. the growth of this organism was investigated by comparing a biphasic system with broth culture. the effects of gyration, inoculum, and ph were studied. brucella agar and broth supplemented with 2.5% fetal bovine serum were used. growth in the biphasic system was an average of 2 log units (7 x 10(8) versus 5 x 10(6) cfu/ml) greater than that in the broth s ... | 1989 | 2768463 |
| gastric metaplasia and campylobacter pylori in duodenal ulcer disease: an ultrastructural analysis. | an ultrastructural analysis was carried out on duodenal mucosa specimens, obtained during duodenoscopy from the edge of ulcers and distal duodenal cap mucosa in 42 patients with active duodenal ulcer disease, and in 12 controls. in 18 of 42 patients (43 p. 100), campylobacter pylori was found in duodenal mucosa but not in controls (chi 2 = 5.91, p less than 0.05). in all 42 cases, gastric-type surface mucus cells were seen at the edge of the ulcer crater, and in 38 of the patients (90 p. 100) th ... | 1989 | 2744326 |
| [campylobacter pylori in children and adults subjected to endoscopy, correlation of endoscopic, bacteriologic and histopathologic findings]. | campylobacter pylori has been associated to peptic ulcer and gastritis. we investigated the presence of c pylori in 17 children and 50 adults who needed endoscopy to investigate upper gastrointestinal symptoms. gram stain, whartin-starry stain and the urease test were used to identify the germ; best results were obtained with the gram stain. c pylori was present in 5.8% of children and 88% of adults, including all patients with peptic ulcer and 36 out of 39 with histologic evidence of gastritis. ... | 1989 | 2749036 |
| [rapid detection of campylobacter pylori]. | 1989 | 2772477 | |
| [campylobacter pylori. determination of gastric colonization and its clinical relevance]. | while evidence suggesting a statistical association between campylobacter pylori and chronic active antral gastritis is convincing, the role which the organism may play in the pathogenesis of this condition and in the case of peptic ulcer remains to be elucidated. the development of safe, non-invasive diagnostic tests suitable for population studies greatly facilitates this investigative process. this article presents a brief review of currently available methods of diagnosing c pylori colonizat ... | 1989 | 2749626 |
| antisecretory treatment and campylobacter pylori. | 1989 | 2753319 | |
| campylobacter pylori, duodenal ulcer, and gastric metaplasia: possible role of functional heterotopic tissue in ulcerogenesis. | multiple pinch biopsies were taken from the duodenum and antrum of 137 subjects (46 active duodenal ulceration; 44 healed ulcers; 47 'normal'), and examined for the presence and grade of gastritis, gastric metaplasia, and campylobacter pylori. these factors, as well as age, sex, cigarette, and anti-inflammatory agent intake were evaluated as possible risk factors for duodenal ulceration. pentagastrin induced congo red staining of the duodenal bulb was performed in an additional 43 cases, to dete ... | 1989 | 2753403 |
| [electron microscopic observations of campylobacter pyloridis in chronic gastritis]. | gastric biopsies from 150 cases of chronic gastritis were studied by electron microscopy. the infection rates of campylobacter pyloridis (cp) were 95.3% (85 cases) and 69.2% (65 cases) in superficial gastritis and atrophic gastritis respectively. a close relationship was seen between quantity of the bacteria and activity of the disease. electron microscopy showed that cp usually damaged the columnar and pit cells of the stomach, resulting in necrosis and active inflammation of the mucosa, and in ... | 1989 | 2776255 |
| serum immunoglobulin g antibody levels for campylobacter pylori diagnosis. | 1989 | 2777037 | |
| 14c-urea breath test in c pylori gastritis. | 14c-urea breath test was used to detect campylobacter pylori colonisation in 129 consecutive non-ulcer dyspepsia patients. fasting patients were given 3 microci (110 kbq) of 14c-labelled urea after a test meal. breath samples were collected at 10 minute intervals for 90 minutes and the c-14 activity was counted on a liquid scintillation analyser. urea derived 14co2 appears in the exhaled breath of campylobacter pylori culture positive individuals within 20-30 minutes. likelihood analysis reveale ... | 1989 | 2753404 |
| the relation between campylobacter pylori and inflammatory cell infiltration of antral mucosa in patients with dyspepsia. | in order to understand the relation between the prevalence of campylobacter pylori and the severity of gastritis, we conducted a survey of 166 randomly selected dyspeptic patients. the presence of c. pylori on the antral mucosa was aseptically determined by both urease and bacterial culture tests. specimens of antral mucosa were obtained for pathologic gradings of inflammation: active gastritis, mononuclear cell infiltration c0 (nil) to c3 (lymphoid follicle); presence or absence of intestinal m ... | 1989 | 2754423 |
| the presence of campylobacter pylori in nonsteroidal antiinflammatory drug associated gastritis. | although campylobacter pylori has recently been causally linked to active chronic gastritis and peptic ulcer disease, its relationship to nonsteroidal antiinflammatory drug (nsaid) associated gastritis is unclear. we performed a case-control study of 100 patients who had undergone gastritis biopsy. blinded review of giemsa stained slides demonstrated the presence of c. pylori in 32% of 19 nsaid treated cases with active chronic gastritis vs 3% of 36 controls with chronic gastritis not taking nsa ... | 1989 | 2754664 |
| antibodies to campylobacter pylori in patients with idiopathic dyspepsia. | we used western blotting analysis to determine the immune profile to campylobacter pylori polypeptides in: a) sera from patients with idiopathic dyspepsia and bacteriological evidence of c. pylori gastric colonization, b) sera from patients with the same symptoms but no bacteriological evidence of c. pylori infection and c) healthy subjects. to avoid interference of aspecific reactions due to antigenic cross reactivity with other thermophilic campylobacter species, antisera were raised in rabbit ... | 1989 | 2779455 |