Publications

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[the urease test for detecting campylobacter pylori: which reactive milieu to choose? at what temperature?]. 19892661296
how specific is the rapid urease test for diagnosing campylobacter pylori? 19892661596
[campylobacter pylori and pathology of the gastro-duodenal mucosa. critical review of clinico-experimental and therapeutic contributions].over the past five years, a series of important contributions have appeared in the medical literature on the role of infective agents in the pathogenesis of gastric and duodenal inflammation. the analysis of the available data confirms the possible role of campylobacter pylori in causing acute inflammation of the type b antral gastritis, although its role in the pathogenesis of gastric and duodenal ulcer and of the socalled non ulcer dyspepsia is still doubtful. not even the results of therapeut ...19892661960
touch cytology, a useful diagnostic method for diagnosis of upper gastrointestinal tract infections.candida albicans, campylobacter pylori, and giardia lamblia are microorganisms that are frequently found in the upper gastrointestinal tract. a cytological smear of biopsies obtained at endoscopy was compared with the pathologic examination of biopsies. candida albicans was found in 55 patients, campylobacter pylori in 54, giardia lamblia in 31; cytology was positive in 43, 46, and 22 cases, respectively, and biopsy in 29, 43, and 22 cases. cytology was thus the only positive test in 26 cases wi ...19892663387
[treatment of chronic gastritis associated with campylobacter pylori]. 19892663587
campylobacter pylori and peptic ulcer therapy. 19892663588
methodological problems of randomized clinical trials in the treatment of duodenal ulcer, "gastritis" and campylobacter pylori infection. 19892663589
the role of campylobacter pylori in gastroduodenal diseases. a "believer"'s point of view. 19892663590
the role of campylobacter pylori in gastroduodenal diseases. a "non-believer"'s point of view. 19892663591
[defense mechanisms of the stomach and campylobacter pylori]. 19892663592
[histologic demonstration of campylobacter pylori]. 19892663595
[bacteriologic methods for the diagnosis of campylobacter pylori]. 19892663596
14c-urea breath test as a method to detect campylobacter pylori colonization.campylobacter pylori may cause type b gastritis. c. pylori produces urease, and the presence of this enzyme in gastric mucosal biopsies is a marker for colonization with the microorganism. the value of a breath test to detect c. pylori colonization in non-ulcer dyspepsia patients was investigated. we compared the 14c-urea breath test with the culture results obtained from antral mucosal biopsies. the 14c-urea breath test is comparable to culture results in detecting c. pylori colonization.19892663597
experimental models in vivo for campylobacter pylori. 19892663598
[contribution of pathologic anatomy to the study of the pathogenicity of campylobacter pylori]. 19892663599
virulence factors of campylobacter pylori. 19892663600
local response of the host to campylobacter pylori. 19892663601
gastric metaplasia in the duodenum and campylobacter pylori. 19892663602
epidemiology of campylobacter pylori infection. 19892663604
bacteriological and pharmacological basis for the treatment of campylobacter pylori infection. 19892663605
biotyping of campylobacter pylori.ninety-one biochemical tests were done on each of 50 strains of campylobacter pylori isolated from the gastric mucosa of patients with gastritis and peptic ulcers in singapore. the api zym system distinguished three biotypes of c. pylori. the organism was found to be biochemically different from c. jejuni and c. coli. we propose a biochemical identification kit that would be of use in identifying and differentiating biotypes of c. pylori, and would distinguish them from c. jejuni and c. coli.19892664183
[the significance of campylobacter pylori infection in gastroenterologic and diabetic practice].the presence of campylobacter pylori was investigated in gastric antral biopsy specimens. in 50 consecutive patients undergoing upper gastrointestinal tract endoscopy microbiological cultures, histological examination and rapid urease test were parallel performed, and a 92 per cent sensitivity and 100 per cent specificity of rapid and cheap urease test were determined. afterwards--in a prospective study--311 patients were examined for c. p. by the rapid urease test only. c. p. was detected in 92 ...19892664637
campylobacter pylori: swedish experiences.all patients referred for gastroscopy were investigated by campylobacter pylori culture and antibody titration. an enzyme immunoassay was developed and found to have a negative predictive value of 0.997, which indicates that serologic tests could be used for screening of patients before gastroscopy. a close correlation was found between active and inactive duodenal and gastric ulcer and positive c. pylori culture. small open treatment trials with the antibiotics doxycycline, tinidazole, amoxycil ...19892665049
review of the modes of action of colloidal bismuth subcitrate.in recent years considerable progress has been made to elucidate the modes of action of colloidal bismuth subcitrate (cbs). cbs accelerates the healing of experimental chronic ulcers in rats by the formation of occlusive complexes and/or the accumulation of epidermal growth factor (egf) in the ulcer crater. cbs exhibits gastric protection (cytoprotection) against, for example, ethanol lesions. microscopic analysis of these lesions reveals that cbs protects against deep mucosal necrosis but not s ...19892665050
the role of campylobacter pylori in the pathogenesis of peptic ulcer disease.most patients with peptic ulceration have chronic gastritis, which typically involves predominantly the antrum. the association between campylobacter pylori-associated gastritis and peptic ulceration has recently been repeatedly demonstrated. evidence is accumulating that the bacterium plays a causal role in type-b chronic gastritis. c. pylori also colonizes the duodenum when gastric metaplasia is present. it is likely that the inflamed mucosa is more susceptible to ulcerogenic influences affect ...19892665051
[non-ulcer dyspepsia and campylobacter pylori].dyspepsia, defined as chronic vague upper abdominal symptoms, is a common condition. the pathogenesis of this syndrome remains poorly understood. the etiologic role of campylobacter pylori and associated gastritis remain controversial though this organism colonizes the gastric antrum in one third to one half of patients with non-ulcer dyspepsia. recent studies raise the prospect that treatment with bismuth improves gastritis and is successful in treating symptoms in the campylobacter pylori posi ...19892667070
[clinical importance of campylobacter pylori. 1]. 19892672271
proteolytic activities of human campylobacter pylori and ferret gastric campylobacter-like organism.the levels of proteolytic activity in cell washes, lysates and pellets of c. pylori and gastric campylobacter-like organisms isolated from humans and ferrets, respectively, have been studied using porcine mucus glycoprotein and bovine haemoglobin substrates. the total haemoglobin degrading activity, expressed by 10(12)-10(13) cfu of either organism, was no greater than 3 micrograms chymotrypsin equivalents. the mucolytic specific activity (rate of mucus peptide bond hydrolysis by bacterial prote ...19892673233
[personal experience with isolation of campylobacter pylori from the gastroduodenal mucosa].during the period between march 1987 and july 1988 the authors examined for the presence of campylobacter pylori bioptic specimens from the gastroduodenum from 410 patients. in the above group they diagnosed by microscopic examination c. pylori in 257 patients (mean 63%). from the whole group 282 patients (100%) were examined concurrently by the microscopic method and by cultivation. this number comprised 195 (68.9%) who were positive on microscopic examination and 110 (42.2%) who were positive ...19892676200
can gastritis symptoms be evaluated in clinical trials? an overview of treatment of gastritis, nonulcer dyspepsia and campylobacter-associated gastritis.we carried out a review of the literature on campylobacter pylori-associated gastritis and nonulcer dyspepsia (nud) to determine whether or not symptoms related to these conditions can be measured reliably and whether or not any study to date has shown that treatment alters symptoms. search strategies consisted of online medline searching, a forward search of three articles using the science citation index, a manual search of five gastroenterological journals, and a fully recursive search of cit ...19892677123
[intragastric formation of ammonia in campylobacter pylori associated gastritis. diagnostic and pathogenetic significance].the diagnostic relevance of measurement of ammonia (nh3) in not stimulated gastric juice in patients with campylobacter pylori associated gastritis (cpag) is in discussion. the role of cp-urease induced nh3 in pathogenesis of active gastritis is unclear. in answering to this questions we evaluated the sensitivity and specifity of nh3-test and clo-test in cases of cpag (n = 50), non cpag (n = 16) and normal gastric mucosa (n = 20). we found a 88% sensitivity and a 86% specifity for nh3-test, a se ...19892677629
[significance of campylobacter pylori in gastritis, non-ulcer dyspepsia and ulcer. a critical observation]. 19892677634
campylobacter pylori: its association with active chronic gastritis.c. pylori is a gram negative spiral bacteria that has been found to be associated with active chronic gastritis and duodenal ulcer. it possesses 4 to 6 sheathed flagella and has cockscrew motility. it is differentiated into 3 main morphological cell types during its cell cycle: spiral, straight rods and coccoid forms. it grows well in enriched media supplemented with sera in the presence of carbon dioxide at 35-37 degrees c. it is a high urease producer, non-sacchrolytic and possesses an array o ...19892679338
[a rapid urease test in campylobacter pylori colonization of the gastric mucosa].biopsies from the gastric mucosa (antrum, corpus) of 145 patients investigated by endoscopy were analysed for campylobacter pylori. the results of bacteriological, histological, enzymatic and chemical methods were compared. urease activity was determined both in biopsies (clo-test) and in gastric secretion. furthermore, the concentration of urea was measured in gastric secretion. 71% of gastritis, 86% of ulcus duodeni and 83% of ulcus ventriculi diagnosed by endoscopy produced positive histologi ...19892679659
campylobacter pylori: its role in gastritis and peptic ulcer disease. 19892679692
[advances in research on campylobacter pylori]. 19892679984
campylobacter associated gastritis in patients with non-ulcer dyspepsia: a double blind placebo controlled trial with colloidal bismuth subcitrate.fifty consecutive patients with non-ulcer dyspepsia and a campylobacter associated gastritis (cag) were randomly assigned to treatment with colloidal bismuth subcitrate (cbs) 240 mg twice daily or placebo, according to a double blind study design. after the blind treatment an 'open' treatment with cbs was started in both groups. twenty six patients treated with cbs showed a significant reduction in colonisation with campylobacter pylori and a significant improvement in the whitehead gastritis sc ...19892680795
[bismuth aluminate in gastroenterology. therapeutic effects in chronic erosive campylobacter pylori-associated gastritis].14 patients with epigastric pain and chronic active gastritis as well as endoscopically proven erosions underwent an open therapeutic trial with bismuth aluminate (3 x 300 mg/day) for three weeks. prior to and after treatment five biopsy specimens were taken from the antral mucosa 2 and 4 cm proximal to the pylorus for histological scoring of inflammatory activity and c. pylori detection, for urease quick test (cut) and culture. before treatment c. pylori was detected histologically and by cut i ...19892680842
isolation of a campylobacter-like organism from healthy syrian hamsters (mesocricetus auratus).a campylobacter-like organism was isolated from the ilea of normal hamsters. the organism was isolated from an ileal homogenate which was passed through a filter (0.65-micron pore size) and cultured on blood-agar plates in a microaerophilic atmosphere at 37 degrees c. pinpoint translucent colonies were first observed after 120 h of incubation. the isolated organism measured 2.0 to 3.5 microns in length (excluding flagella) by 0.17 to 0.25 micron in width and typically had a single terminal sheat ...19892681250
campylobacter pylori. diagnosis and treatment.there is now a plethora of methods to diagnose colonization of the human stomach with campylobacter pylori, such as microbiological culture on various media, identification of c. pylori in biopsies or biopsy smears using various stains or neurological methods, serological demonstration of specific anti-c. pylori antibodies, measuring urease activity with one of the many urease tests or using the 13c- or 14c-urea breath test. therapy should be directed at permanent eradication of the organism. er ...19892681390
[experience with the treatment of duodenal ulcer associated with campylobacter pylori infection by combined use of anti-secretory and antibacterial drugs]. 19892681993
[analysis of the prevalence of anti-campylobacter pylori antibodies detected in a healthy human population].a study was made of the prevalence of anti c. pylori in the healthy adult population. the analytical method used was indirect immunofluorescence. an analysis was made of 231 sera (122 males and 109 females) from subjects 20 to 82 years-old. the global positivity detected was 21.1%. there was a slight rise in the percentage of positivities as age increased, reaching the maximum rate in the group over 50 years (2.1%). the titers detected were low and unrelated to age. no significant differences by ...19892682831
duodenal ulcer disease: what role does campylobacter pylori play?duodenal ulcer is a chronic relapsing condition which only became common early this century. many pathogenic factors have been identified including excess gastric acid secretion, cigarette smoking, non-steroidal anti-inflammatory drugs and reduced mucosal defence. there is a strong association of duodenal ulceration, gastric campylobacter pylori and antral (type-b) gastritis. the link between ulceration in the duodenum and c. pylori-associated antral gastritis may lie in the formation of gastric ...19892683020
pathogenicity of campylobacter pylori--a causative factor in gastritis?there is now much worldwide evidence that campylobacter pylori plays a pathogenic role in the aetiology of gastritis rather than colonizing an already inflamed gastric mucosa. 1) there is a very close association between the presence of c. pylori on the gastric mucosa and histologically confirmed type b chronic active gastritis. ninety percent of patients with c. pylori infection have gastritis whereas less than 5% of patients with normal mucosa are colonized. 2) c. pylori only colonizes gastric ...19892683021
campylobacter pylori--therapy review.although campylobacter pylori is sensitive to many antibiotics in vitro, few are effective in vivo. furthermore, treatment regimens which successfully clear the organism in vivo are associated with high recurrence rates when assessed one month following treatment. on the other hand, 85% of those individuals who are c. pylori negative 1 month after the cessation of therapy remain negative at 12 months and the infection can be considered to be eradicated. treatment with certain bismuth salts appea ...19892683022
campylobacter pylori and ulcer disease--a causal connection?a strong positive correlation has been demonstrated between the (antral mucosal) presence of campylobacter pylori and active duodenal and gastric ulceration. moreover, both duodenal and gastric ulcers heal, and remain in remission, as a consequence of therapeutic measures which eradicate c. pylori. however, the henle-koch postulates have not been fulfilled, because c. pylori has not been shown to produce ulcers. as for the claim that ulcer disease represents an infection with c. pylori because t ...19892683023
campylobacter pylori--a role in non-ulcer dyspepsia?non-ulcer dyspepsia (nud) is a common complaint in which no systematic illness or organic proximal alimentary tract disease can be identified. the pathophysiology of nud is probably heterogeneous. eighty-two subjects with nud were studied in a prospective randomized placebo-controlled study to assess the efficacy of colloidal bismuth subcitrate (cbs) chewable tablets at a dose of four tablets daily for 1 month. the role of campylobacter pylori and associated histological gastritis was evaluated. ...19892683024
[campylobacter pylori and its relation to gastritis and peptic ulcer]. 19892683520
minitek urea disk test, a sensitive and cost-effective method to screen for campylobacter pylori in gastric biopsies.one hundred fifty-five biopsy specimens from the gastric mucosa of 81 patients undergoing routine endoscopy procedures were tested for the presence of campylobacter pylori by three methods: gram stain, culture, and modified minitek, a rapid urea disk test (bbl microbiology systems, cockeysville, md.). twenty-nine patients were infected with c. pylori. sensitivities and specificities of detection were 100 and 94% with the minitek test and 93 and 100% with gram stain, respectively. rapid testing b ...19892687317
gastric campylobacter-like organisms: their role in gastric disease of laboratory animals.campylobacter pylori, first isolated in 1982, is now recognized as a primary cause of acute gastritis in man, and there is substantial data suggesting that this organism also plays an important role in the pathogenesis of duodenal ulcers. more recently, campylobacter-like organisms and other morphologically distinct spiral bacteria have been isolated from gastric lesions in a variety of laboratory animal species. the zoonotic significance of c. pylori and other gastric spiral bacteria isolated f ...19892687581
recurrence of duodenal ulcer and campylobacter pylori infection after eradication.the role of campylobacter pylori gastritis in dyspepsia could be clarified more readily if reliable eradication therapy were available. antibiotic monotherapy and combined therapy with an antibiotic agent plus a bismuth compound have yielded poor long-term results. in this study, bismuth-tetracycline-metronidazole triple therapy has been used to eradicate c. pylori infection in 100 consecutive patients who were suffering from either a duodenal ulcer or non-ulcer dyspepsia. examination of a follo ...19892687668
is antibacterial therapy against campylobacter pylori useful in the treatment of indigestion and chronic peptic ulceration?campylobacter pylori is a spiral gram-negative rod that was first identified in human gastric mucosa in 1906. since 1983, interest in the organism has been renewed; it was first cultured, and has since been found to be very strongly associated with the histologic presence of antral gastritis. further, it has been suggested that this organism may play a role in peptic ulceration. c. pylori is sensitive to many different antibiotics as well as to bismuth. however, recrudescence of infection after ...19892688215
[has campylobacter pylori infection any clinical relevance? methodologic, epidemiologic and clinical studies].the occurrence of campylobacter pylori (cp) was studied in 180 patients referred for endoscopy. the bacterium was detected by culture, histology (warthin-starry staining) and urease test of antral biopsy samples. patient groups were formed according to endoscopic diagnoses, clinical symptoms and antral mucosal histology. 50 cp positive patients with chronic antral gastritis were treated by bismuth subsalicylate (2,4 g/day) for 3 weeks. positivity by culture and/or silver-stained histology proved ...19892689946
antigenic conservation of the ureases of spiral- and helical-shaped bacteria colonising the stomachs of man and animals.a monoclonal antibody, cp11, has been produced which is directed against the ureas of campylobacter pylori. this antibody has been used to look for antigenic cross-reactivity, in other ureolytic and non-ureolytic campylobacters, by immunohistological techniques. it has also been used to investigate the helical-shaped organisms found in the stomach of the human, monkey and cat (cs1) and the ileum of the rat (st1). interestingly the antibody cross-reacted with the gastric helical organisms from th ...19892693196
[clinical importance of campylobacter pylori. second part]. 19892694295
campylobacter pylori and non-ulcer dyspepsia. 1. the final results of a double-blind multicentre trial for treatment with pirenzepine in italy.in a double-blind multicentre trial to study the effect of pirenzepine in the treatment of non-ulcer dyspepsia, 104 of 128 patients, 52 in each of the study and control groups, completed the 4 weeks of the investigation. there was improvement of the endoscopic and clinical findings but no change of the degree of the mucosal inflammation or the extent of colonisation by campylobacter pylori. the mode of action of pirenzepine in patients with non-ulcer dyspepsia associated with campylobacter relat ...19892694330
[pathogenetic properties of campylobacter pylori]. 19892696836
successful lyophilization of campylobacter pylori and spiral organisms from the stomachs of animals. 19892696921
[characteristics of the endoscopic diagnosis of peptic ulcer and chronic gastritis associated with campylobacter pylori]. 19892699098
campylobacter pylori detection by rapid urease test. 19892699989
[campylobacter pylori gastritis: review of diagnostic methods].the presence of campylobacter pylori in gastric mucosa is a proof of active gastritis. diagnostic methods are based on endoscopy: culture--histology--cytology--urease test, or on noninvasive tests: c14 urea breath test and serology. the principles, results (sensitivity--specificity), advantages and problems of each test are discussed as well as the choice of a diagnostic method. in practice, we recommend the use of two methods, a morphological one (histology or cytology) and another based on bac ...19892700272
campylobacter pylori as possible factor in peptic ulcer recurrence.the author reviews the literature up to 1988 about the close association of campylobacter pylori with chronic active gastritis, duodenitis and peptic ulcer disease. no firm data however demonstrate that campylobacter pylori causes duodenal ulcer but long term eradication of this bacterium prevents duodenal ulcer relapse.19892700273
[campylobacter pylori in diseases of the stomach and duodenum].campylobacter pylori is an organism living under mucus layer in the stomach and on the places of gastric mucosa metaplasia. it is known to be responsible for the development of gastritis, probably also it participates in the pathogenesis of dyspepsia without ulcer, while its role in the development of gastric and duodenal ulcer has not yet been explained completely. the authors present a characteristics of the organism and the methods of its detection. a number of investigations are discussed wh ...19892701041
[the microbiological diagnosis of chronic gastropathy associated with campylobacter pylori].the efficiency was studied, in experimental and practical conditions, of media for the isolation of c. pylori, as well as criteria for diagnosis and identification. the highest sensitivity was obtained with columbia gelose, and a lower sensitivity was achieved with campy i. c. gelose, and with heart-brain gelose, prepared as chocolate gelose, and columbia gelose with integral blood. both variants of the mueller-hinton gelose, even in the chocolate formula, gave negative results. of the fluid med ...19892701344
[what should surgeons know about campylobacter pylori?]. 19892704282
[epidemiology and therapy of campylobacter pylori infection].the prevalence of campylobacter pylori in gastric mucosa was investigated prospectively (by histology, cytology, bacterial culture and urease rapid-test) in 302 patients of a routine gastroenterological endoscopy programme. according to the histopathological findings the following prevalence of c. pylori was established: 3 of 35 normals (9%); 116 of 167 with antral gastritis (69%), 28 of 40 with gastric ulcers (70%); 26 of 33 with duodenal ulcers (79%); 5 of 27 with other conditions (19%). the a ...19892707124
[campylobacter pylori compels re-thinking]. 19892709948
[campylobacter pylori and gastritis--the density of colonization and degree of inflammation. a semiquantitative and morphometric study].gastric biopsies of 1000 patients were grouped according to their diagnoses, special interest was devoted to type b-gastritis. density of campylobacter pylori colonization was determined semiquantitatively after warthin-starry silver impregnation. bacteria could never be seen in normal mucosa. in b-gastritis statistics proved a significant correlation between bacterial colonization density and degree of inflammation. in 60 selected cases this close interrelation could be objectified by morphomet ...19892709949
[clinico-endoscopic characteristics and laboratory diagnosis of chronic campylobacter gastritis in childhood].altogether 31 children with chronic gastritis were examined. three diagnostic tests were employed for detecting campylobacter pylori. the clinical signs of the disease and the endoscopic features of the gastric mucosa are described.19892710607
comparative in vitro activities of six new fluoroquinolones and other oral antimicrobial agents against campylobacter pylori.the in vitro susceptibilities of 56 clinical isolates of campylobacter pylori to six new fluoroquinolones and other oral antimicrobial agents were determined by an agar dilution technique. ciprofloxacin was the most active of the fluoroquinolones (mic for 90% of strains tested [mic90], 0.05 microgram/ml). other fluoroquinolones had variable activities, although most isolates were moderately susceptible to fleroxacin (mic90, 4 micrograms/ml) and lomefloxacin (mic90, 4 micrograms/ml).19892712542
nonsecretors and peptic ulceration. no link with campylobacter pylori. 19892714155
rapidly decreased serum igg to campylobacter pylori following elimination of campylobacter in histological chronic biopsy campylobacter-positive gastritis.the anaerobic bacterium campylobacter pylori (cp) is thought to be associated with chronic gastritis. this paper presents clinical data underpinning this view. five patients with histological chronic gastritis as determined by diagnostic endoscopy, which was associated with cp as determined by positive biopsy cultures, all possessed statistically raised serum igg elisa titers to cp during a longitudinal period of observation of 15 months. treatment with the antibiotics amoxycillin (clamoxyl) or ...19892714840
ultrastructure and chemical analysis of campylobacter pylori flagella.flagella of campylobacter pylori were analyzed by electron microscopy and purified, and the molecular weight of the flagellin was determined. isolation of flagella was performed by mechanical shearing from the cell surface, sucrose density gradient centrifugation, and sepharose cl-4b gel chromatography. the flagella of c. pylori differ from those of other campylobacter species and of most other bacteria by the presence of a flagellar sheath. the sheath narrows at the end and is linked to a club- ...19892715319
gastric metaplasia and campylobacter pylori infection of duodenum in patients with chronic renal failure.duodenal biopsy specimens from 80 patients with chronic renal failure, who were undergoing haemodialysis, were examined by light microscopy for evidence of inflammation, gastric metaplasia, and campylobacter pylori infection. chronic duodenitis was present in 47 (59%) of patients, of whom only seven (9%) showed evidence of active inflammation. gastric metaplasia was present in 50 (62.5%) of patients, yet campylobacter pylori was identified in only two patients (2.5%). it is suggested that the du ...19892715348
[diagnosis and treatment of gastric campylobacteriosis in patients with peptic ulcer and chronic gastritis].the endoscopic picture of peptic ulcer was studied in 104 patients; the gastric mucosa of 30 per cent of the patients was infected with campylobacter pyloridis (cp) and had acute erosions in the pyloroduodenal zone. erosions in uninfected patients were found in 3 per cent of the cases. the predominant lymphoid infiltration of the mucous coat of the stomach was revealed in 60 ulcer patients irrespective of the cp infection. mucous infiltration with polymorphonuclear leukocytes was found in 13 chr ...19892716260
[the effect of a calcium carbonate-bismuth subsalicylate combination on intragastric acidity over the course of 24 hours. a randomized study of healthy probands].bismuth salts are successfully used for the treatment of campylobacter-pylori-associated gastritis. it cannot be excluded, however, that calcium carbonate, which is present in one of the recommended preparations (calcium carbonate/bismuth subsalicylate, jatrox), may have an additional therapeutic effect due to an increase of intragastric ph. therefore, the in-vitro h+ buffering capacity of jatrox was determined in comparison to other antacids using the ph-stat technique, and its effect on intrag ...19892716711
campylobacter pylori and large gastric folds. 19892717728
enlarged gastric folds in association with campylobacter pylori gastritis.enlarged gastric folds in pediatric patients are uncommon. fifteen patients with upper gastrointestinal (gi) tract symptoms of chronic epigastric abdominal pain, vomiting, or hematemesis underwent radiologic upper gi barium studies and were found to have campylobacter pylori gastritis at endoscopic biopsy. seven patients (47%) with c pylori gastric disease had radiologic evidence of enlarged folds. there was no clinical or pathologic evidence of ménétrier disease. therefore, c pylori gastritis s ...19892717759
patterns of physical modes of contact between campylobacter pylori and gastric epithelium: implications about the bacterial pathogenicity.since the exact mechanisms of the pathogenicity of campylobacter pylori are not known, we performed an ultrastructural study with the aim of focusing on patterns of possible physical contact between c. pylori and gastric epithelium, and of considering them in relation to the bacterial pathogenicity. among 20 random consecutive patients referred for routine gastroscopy, we studied ultrathin sections from the 11 patients with campylobacter-like organisms, and recognized three patterns of physical ...19892719007
treatment failure of norfloxacin against campylobacter pylori and chronic gastritis in patients with nonulcerative dyspepsia.several reports have been published to show the in vitro susceptibility of campylobacter pylori to different classes of antibiotics, including fluoroquinolones. the purpose of this study was to describe the clinical effect of norfloxacin on eradication of c. pylori in patients with gastritis. endoscopy was performed in 38 patients with symptoms of nonulcerative dyspepsia. of these, 20 patients had a c. pylori-positive culture. from this group, 17 patients were treated with norfloxacin for 1 mont ...19892719469
[campylobacter pylori, its endoscopic detection in childhood]. 19892720817
two-dimensional gel electrophoresis and immunoblotting of campylobacter pylori proteins.whole-cell, outer-membrane protein, flagellum-associated antigens and partially purified urease of campylobacter pylori were analyzed by two-dimensional gel electrophoresis. c. pylori strains were readily distinguished from strains of campylobacter jejuni, c. coli, and c. fetus by absence of major outer membrane proteins with mrs of 41,000 to 45,000. c. pylori strains also lacked the acidic surface-array proteins at mr 100,000 to 149,000 identified previously in serum-resistant strains of c. fet ...19892722241
[incidence, intensity and clinical manifestations of antral gastritis in duodenal ulcer in women and their relation to campylobacter pylori].it was established during examination of 120 women with duodenal ulcer that in 48 percent of them the clinical disease manifestations were typical. in patients with an atypical disease course, the painful syndrome was not pronounced. it was not dependent on food intake or season. 34.2 percent of the patients had, instead of pains, a feeling of heaviness in the epigastric area, heartburn and eructation depending on the antral gastritis severity. the ulcers measured 5 mm and less in 75.6 percent o ...19892727917
[campylobacter pylori in chronic gastritis].altogether 301 patients with duodenal, gastric and prepyloric ulcers and non-ulcer controls were examined to study whether the campylobacter pylori is related to ulcer itself or to coexisting chronic gastritis. histological sections from antral and body mucosa were stained according to warthin-starry, giemsa and with hematoxylin-eosin. the campylobacter pylori was strongly associated with chronic superficial gastritis in both ulcer and non-ulcer patients and in both antral and body mucosa. no di ...19892727918
prevalence of campylobacter pylori in patients undergoing upper endoscopy.from august 1987 through july 1988, we evaluated antral biopsy specimens for campylobacter pylori (cp) in 212 patients undergoing upper endoscopy. for those patients who had multiple endoscopies, the first endoscopy in which a urease test, histology, and culture were done was used to determine cp status. a patient was regarded as cp-positive if the culture was positive or if both a urease test and the histology were positive. blacks had an increased cp positivity (61.2%) compared to whites (31.5 ...19892729234
campylobacter pylori in patients with dyspeptic symptoms and endoscopic evidence of erosion(s).the relationship between campylobacter pylori (cp), histologic gastritis, and dyspeptic symptoms is becoming gradually clearer, but there is still a lack of knowledge of the natural history of treated or untreated gastritis. we examined serial biopsies from the gastric fundus, body, and antrum, and from the duodenum in 16 dyspeptic patients. patients with concomitant peptic ulcers, alcoholism, or nonsteroidal anti-inflammatory drug use were excluded. cp was present in the biopsies of 50% of pati ...19892729235
campylobacter pylori: "all that glitters is not gold". 19892729249
prevalence of campylobacter pylori in esophagitis, gastritis, and duodenal disease.the relationship between the presence of campylobacter pylori and esophagitis was studied in patients undergoing paired biopsies of distal esophagus and gastric antrum during esophagogastroduodenoscopy. biopsy specimens were examined for urease activity and for the presence of c pylori by culture and by histologic examination of hematoxylin-eosin- and warthin-starry-stained sections. sixty-two patients were entered into the study. all esophageal biopsy specimens, regardless of histologic finding ...19892730254
[histologic study of campylobacter pylori: role of fixation]. 19892731687
[campylobacter pyloridis in duodenal ulcer].a morphologic study of antral gastric and duodenal mucosa was carried out in patients with duodenal ulcers. peptic ulcers were in the phase of exacerbation in 55 patients, and that of remission, in 10. campylobacter pyloridis (cp) were detected in 83% of the cases by histologic investigation of gastric and duodenal mucosa biopsy specimens obtained from patients with duodenal ulcers. cp were more common and numerous during exacerbation rather than remission of peptic ulcers. bacterial disseminati ...19892734670
[antibacterial treatment of campylobacter pylori-associated gastritis and peptic ulcer].on the basis of possible etiological or pathogenetic significance of campylobacter pylori for the development, maintenane og recurrence of gastritis and peptic ulceration, a review based on the literature is presented for the sensitivity of the bacteria in vitro and in vivo to antibiotics and preparations employed in the medicinal treatment of gastritis and peptic ulceration. the bacterium is sensitive in vitro to a long series of antibiotics and all of the anti-ulcer agents have, similarly, ant ...19892734863
[gastritis and ulcer: reconsidering therapy? report from a presymposium: "campylobacter pylori--value of therapy today". 3 march 1989, taormina/sicily. abstracts]. 19892737588
new spiral bacterium in gastric mucosa.a new spiral bacterium, distinct from campylobacter pylori, was found in the gastric mucosa of six patients with gastrointestinal symptoms. all patients had chronic active type b gastritis and four had oesophagitis. culture and microscopy for c pylori infection was negative. these unculturable spiral organisms were probably an incidental finding in patients presenting for upper gastrointestinal endoscopy, but it is not possible to say from this small series whether these organisms cause chronic ...19892738164
no acid, no polys--no "active" gastritis, no dyspepsia. a proposal.the current dilemma in characterizing non-ulcer dyspepsia (nud) is due to the very nature of the term which has forced the dependence for diagnosis primarily on symptomatology and the absence of an ulcer crater as ascertained by radiographs or endoscopy. i propose a new classification which i believe is consistent and well founded, based on the presence of histologic gastritis and acid secretion of the stomach. four categories are presented: (a) normal histology, (b) "active" gastritis, (c) "ina ...19892738355
campylobacter pylori and trials of ulcer recurrence. 19892738364
pediatric upper gastrointestinal endoscopy: a 13-year experience.this report describes a series of 553 flexible upper gastrointestinal (gi) endoscopies performed on 382 children in two surgical centers between 1975 and 1987. indications included abdominal pain (180), reassessment of known disease (149), upper gi bleeding (99), foreign body ingestion (77), vomiting (14), dysphagia (10), and miscellaneous (24). findings were chronic peptic ulcer (47), gastritis/duodenitis (63), healing disease (92), nonhealing disease (22), recurrent disease (32), foreign body ...19892738808
scanning electron microscopy in the study of campylobacter pylori associated gastritis.the close association between campylobacter pylori (cp), gastritis and peptic ulcer is now well established. moreover increasing evidence has been collected of a major etiological role of cp in type b chronic gastritis. for this reason, searching for cp is essential in all patients with upper gastrointestinal symptoms. scanning electron microscopy (sem) is a most reliable technique for studying the distribution of microorganisms and their relationship to the gastric mucosal surface. the aim of t ...19892740873
the upper gastrointestinal microflora in relation to gastric diseases and gastric surgery.the upper gastrointestinal microflora was evaluated in relation to gastric diseases and gastric surgery. postoperative septic complications and microorganisms found in primary infections were studied in 750 gastric operations. the overall rate of primary infections was 23%. enterobacteriaceae, enterococci and bacteroides fragilis were more frequently found in postoperative infections in patients with gastric bleeding or carcinoma. the microbial colonization of the oropharynx, esophagus and stoma ...19892741634
campylobacter pylori-associated gastritis and immune response in a population at increased risk of gastric carcinoma.a series of 169 consecutive patients from low socioeconomic strata attending the gastroenterology clinic of charity hospital in new orleans were evaluated clinically and endoscopically. this general new orleans population is known to be at increased risk of developing gastric carcinoma. the type of gastritis was identified histologically, and the presence of campylobacter pylori was determined by culture and/or histology. the overall prevalence of c. pylori infection in this patient population w ...19892741887
urease tests for campylobacter pylori detection. 19892741898
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