Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| evaluation of liquid media for growth of helicobacter pylori. | helicobacter pylori has routinely been isolated and grown on solid media. recently, we have succeeded in obtaining growth of this organism in several liquid media in large volumes, including tryptic soy broth, mueller-hinton broth, brucella broth, brain heart infusion broth, and columbia broth. growth was tested in the media with and without supplementation. growth was obtained after incubation under microaerobic conditions and with co2 enrichment. growth in a stationary system versus that in an ... | 1991 | 1757556 |
| dyspeptic complaints, diet, gastric mucosa and helicobacter pylori among an estonian urban population. | a representative sample of an adult population, earlier examined by gastroscopic biopsy, was subjected to correlation and regression analyses to quantitate the influences of different factors on the development of three dyspeptic complaints. in this study a large part of the complaints were incriminated by the subjects to poor tolerance of certain foods and/or beverages. according to the results of formal analysis, the state of the corpus and antral mucosa and the presence of helicobacter pylori ... | 1991 | 1759115 |
| helicobacter pylori in dyspeptic patients: quantitative association with severity of gastritis, intragastric ph, and serum gastrin concentration. | the relationship between different features of gastric mucosal inflammation, intragastric ph and serum gastrin concentration and the distribution and quantity of helicobacter pylori was studied in a series of 107 dyspepsia patients. h. pylori was identified in 62 cases (59%), and its presence was associated with increased amounts of mononuclear inflammatory cells and neutrophilic and eosinophilic leucocytes in both the antrum and the corpus. the number of h. pylori in the antral mucosa was signi ... | 1991 | 1759120 |
| grade of helicobacter pylori colonisation in relation to gastritis: a six-year population-based follow-up study. | the prevalence and density of helicobacter pylori (hp) colonisation was assessed twice, with an interval of six years from antral and corpus biopsies from a randomly collected estonian urban population sample. positive hp colonisation was found in either at 1st or 2nd or in both examinations in 85 out of 86 subjects in whom gastritis without atrophy (chronic inflammation without atrophic changes, sg) either developed or remained during the follow-up at the sg level. there was a clear intraindivi ... | 1991 | 1759122 |
| young onset peptic ulcer disease and non-ulcer dyspepsia are separate entities. | the characteristics of peptic ulcer and non-ulcer dyspepsia in young men were studied in 202 consecutive conscripts who attended central military hospital in helsinki because of long-standing upper abdominal complaints. active peptic ulceration (apu) was found in 48 patients, inactive peptic ulcer disease (ipu) was diagnosed in 77 patients, non-ulcer dyspepsia (nud) was diagnosed in 52 patients. in 25 cases the reason for symptoms was another disease, and these patients were excluded from the st ... | 1991 | 1759126 |
| helicobacter pylori and duodenal ulcer. a study of duodenal ulcer patients and their first-degree relatives. | out of 59 duodenal ulcer (du) probands and their 199 first-degree relatives giemsa-staining for the determination of helicobacter pylori (hp) was performed in 51 probands and 155 relatives. controls were matched by age and sex from a family sample representing the same geographical area. in all, 155 controls were found for the probands and relatives. the occurrence and score of hp density showed an excellent correlation with morphology of the mucosa, signs of acute inflammation and presence of g ... | 1991 | 1759128 |
| helicobacter pylori and chronic gastritis: an increased risk of peptic ulcer? a review. | 1991 | 1759130 | |
| grade of helicobacter pylori colonisation, chronic gastritis and relative risks of contracting high gastric ulcers: a seven-year follow-up. | a series of 38 patients with high gastric ulcer (gu) was examined twice a seven-year interval. one-third of the patients had an active ulcer at the second examination. chronic gastritis was evaluated, and the level of helicobacter pylori (hp) colonisation assessed semiquantitatively. the results were compared with age and sex matched non-ulcer controls. the gu series differed from the controls in having a higher degree of hp colonisation in gastric mucosa. the relative risks (rr) in predicting h ... | 1991 | 1759132 |
| spiral organisms: what are they? a microbiologic introduction to helicobacter pylori. | the stomach provides a hostile environment to most microorganisms owing to the antibacterial effect of gastric acidity. however, over the period of mammalian evolution a highly specialized group of bacteria has evolved to inhabit the gastric mucosa. the common features of these bacteria that allow survival in the stomach and colonization of their natural ecologic niche, mucus, are a specialized form of motility, microaerophilism, and very high activity of the enzyme urease. other important adapt ... | 1991 | 1775930 |
| helicobacter pylori infection and gastroduodenal injury by non-steroidal anti-inflammatory drugs. | helicobacter pylori infection with active gastritis is comparably common in non-steroidal anti-inflammatory drug (nsaid) users and controls. the prevalence of active acute gastritis and its severity relate to h. pylori infection and not to use or non-use of nsaids. in individual patients active gastritis may deteriorate during long-term nsaid therapy but is rare in aspirin users. among nsaid users those with h. pylori gastritis appear to have more dyspeptic symptoms, repeated intolerance to diff ... | 1991 | 1775931 |
| helicobacter pylori, causation, change in natural history, and why helicobacter-positive duodenal ulcers should not be routinely treated. | the relationship between helicobacter pylori and duodenal ulcer is reviewed with regard to the following epidemiologic issues: causation, change in natural history, and whether there is sufficient evidence to treat h. pylori-positive peptic ulcers routinely. there is mounting evidence for a pivotal role of h. pylori as a precipitating cause of duodenal ulcers. there is insufficient data to conclude that eradication of h. pylori alone will cure peptic ulcer disease--that is, preventing instead of ... | 1991 | 1775932 |
| long-term effect of vagotomy on gastric mucosa and helicobacter pylori in duodenal ulcer patients. | the purpose of the study was to evaluate the long-term effects of vagotomy on the morphological status and helicobacter pylori infestation of the gastric mucosa. endoscopy with biopsies (2 from antrum and 2 from corpus) was performed in 317 patients on whom vagotomy had been performed on an average 8 years earlier. the success of the vagotomy was estimated by the endoscopic congo red technique in 270 cases. non-operated 187 duodenal ulcer patients were examined endoscopically and bioptically in ... | 1991 | 1759134 |
| helicobacter pylori: histological and serological study on gastric and duodenal ulcer patients in estonia. | we have examined the occurrence of helicobacter pylori (hp) infection in 86 estonian gastric ulcer (gu) and 25 duodenal ulcer (du) patients. diagnosis of the hp infection was made histologically (modified giemsa) from gastric biopsy specimens, and serologically by parallel use of two enzyme-linked immunosorbent assays for igg antibodies to hp in patient sera. the infection was diagnosed simultaneously by all three methods in 84% of the gu and 84% of the du patients. the infection was revealed hi ... | 1991 | 1759135 |
| [helicobacter pylori colonization in surgical patients]. | the prevalence of helicobacter pylori (hp) was examined in 387 patients undergoing endoscopy of the upper gastrointestinal tract. of central interest was the question to which extent surgical intervention influences the colonisation of the gastric mucosa with hp. the bacillic status was appraised using double microbiological examinations, histological determination and the clo-test. in 229 patients a 13c-urea-breath test was also carried out (sensitivity 98%). hp could be detected in 90% of all ... | 1991 | 1760952 |
| [helicobacter pylori infection and the surgically treated stomach]. | in 38 patients who had been operated for peptic ulcer (32) or gastric cancer (6), we performed upper gi endoscopy with biopsies. hp was found in the mucosa in 8 out of 10 patients with highly selective vagotomy, 5 out of 11 patients with gastrectomy for ulcer, 6 out of 11 patients with vagotomy-pyloroplasty and in only 1 case out of 6 with gastrectomy for cancer. these results are in agreement with other publications. bilio-pancreatic reflux into the stump probably explains why hp was found in o ... | 1991 | 1781613 |
| the effect of bile acids on the growth and adherence of helicobacter pylori. | bile reflux gastritis occurs in the absence of helicobacter pylori (h. pylori). the aim of this study was to see if the bile acids cheno or ursodeoxycholic acid affected the growth or adherence of h. pylori in vitro. twenty-seven strains growth were inhibited by 0.1% chenodeoxycholic acid whereas only 11 out of the 27 were inhibited by 0.1% ursodeoxycholic acid. growth was totally inhibited by a combination of 0.05% chenodeoxycholic acid +0.05% ursodeoxycholic acid. chenodeoxycholic acid was a m ... | 1991 | 1782308 |
| role of mucus in gastric mucosal protection. | even though there is no general agreement as to the mechanism of gastric mucosal protection, the consensus is that the initial brunt of luminal insults falls on the mucus layer which constitutes the only identifiable physical barrier between the gastric lumen and the mucosal surface. the continuous renewal and resilient nature of this layer efficiently counters peptic erosion of the gel, assures its viscoelastic and permselective properties, and provides a milieu for containment of the diffusing ... | 1991 | 1782415 |
| effect of biliary tract procedures on duodenogastric reflux and the gastric mucosa. | the effect of alterations in the biliary tract on the gastric milieu was evaluated in gallstone disease and after cholecystectomy or biliary fenestration and compared with a control group. endoscopic bile reflux was often found in gallstone patients (67%) and almost always after cholecystectomy (89%). gastric bile acid concentrations were greater in the gallstone patients than in the control patients, were higher still after cholecystectomy, and were highest after biliary fenestration. the ph of ... | 1991 | 1763297 |
| [relationship between helicobacter pylori and antral gastritis and gastroduodenitis]. | morphological data on the biopsies obtained from the antral gastric mucosa of 150 chronic gastritis and gastroduodenitis patients provided grounds for recognition of 3 degrees of gastritis activity. helicobacter pylori (cp) occurred in the antral gastric portion in 100% of the cases. cp presence and mucosa contamination, plasmocytic infiltration, dystrophic changes in the surface and glandular epithelium were found to correlate. administration of ampiox in a daily dose of 1.0 g for 10 days resul ... | 1991 | 1766223 |
| [the role of helicobacter pylori in the development of chronic gastritis and gastroduodenal ulcers]. | to determine the correlation between helicobacter pylori colonization of the gastric mucosa and the incidence of chronic gastritis as well as gastric and duodenal ulcer, 52 patients (26 women and 26 men) aged 19-77 years (mean 46 years) with gastrointestinal symptoms were studied. biopsy specimens for histological and bacteriological examinations were taken during upper gastrointestinal tract endoscopies. helicobacter pylori was found in 21 (40%) patients: 14 women and 7 men (p less than 0.05). ... | 1991 | 1784540 |
| [clinical characteristics of gastric infection caused by helicobacter pylori]. | in a series of 150 patients submitted for diagnostic gastroscopy, a prospective study of nine anamnesis variables and four exploratory ones was done. endoscopic and histopathologic diagnoses, as well as the clinical data, were obtained by blinded observers. helicobacter pylory (hp) presence in antral mucosa was determined by culture. a clear relationship between hp presence and peptic ulcer disease, bulboduodenitis and histologic gastritis was found, as expected, but no clinical variable correla ... | 1991 | 1784797 |
| severe helicobacter pylori infection in a patient with aids. | a 30-year-old man with aids presented with symptoms of fever, epigastric pain and weight loss, together with histological findings of helicobacter pylori-induced gastritis. his symptoms resolved with treatment, as indicated by the clearing of his h. pylori infection on repeat gastric biopsy. although uncommon, h. pylori infection can cause severe illness in patients with aids. | 1991 | 1786152 |
| [campylobacteriosis in clinical practice]. | 1991 | 1787672 | |
| prevalence of helicobacter pylori in nonulcer dyspepsia. | 1991 | 1789883 | |
| [isolation and identification of bacteria of the genera campylobacter and helicobacter]. | 1991 | 1789898 | |
| prevalence of helicobacter pylori in patients with end-stage renal failure and renal transplant recipients. | the prevalence of helicobacter pylori was determined using an elisa technique for igg antibodies to h. pylori in 76 patients with end-stage renal failure who were receiving regular haemodialysis and 202 patients with functioning renal transplants. twenty-seven (34%) of the haemodialysis group and 58 (29%) of the transplant group were positive for h. pylori igg antibodies, and the prevalence did not differ significantly from that in 247 age-matched healthy controls. in the haemodialysis group, pa ... | 1991 | 1766499 |
| [the significance of helicobacter pylori in the pathogenesis of peptic ulcer]. | 1991 | 1792762 | |
| [duodenal ulcer: long-term treatment]. | 1991 | 1792843 | |
| the role of helicobacter pylori in gastroduodenal disease. | peptic ulcers are the result of a wide variety of factors, with h. pylori probably being one of the more significant. h. pylori has been most strongly associated with gastritis and duodenal ulcer disease. the relationship of h. pylori to gastric ulcers is less substantial. the eradication of h. pylori can be achieved in the majority of patients with triple antibiotic therapy. however, resistance to metronidazole occurs readily. eradication of h. pylori can change the course of duodenal ulcer dis ... | 1991 | 1769198 |
| evaluation of a commercial latex test for serological diagnosis of helicobacter pylori infection in treated and untreated patients. | the value of a commercially available latex test (pyloriset) for the diagnosis of helicobacter pylori infection by demonstration of specific antibodies was compared with that of direct diagnostic methods such as culture, biopsy-urease test and microscopy of fuchsin-stained smears. the sera were from 136 patients who prior to this study either had or had not been treated for helicobacter pylori-infection simultaneously with amoxicillin (3 x 750 mg/day) and metronidazole (3 x 500 mg/day) for 12 da ... | 1991 | 1794371 |
| gastritis and helicobacter (campylobacter) pylori--merely one more piece in the jigsaw puzzle or the final answer? | 1991 | 1794913 | |
| development of sustained achlorhydria in a patient with the zollinger-ellison syndrome treated with omeprazole. | spontaneous remission of gastric acid hypersecretion in the zollinger-ellison syndrome occurs rarely. this study shows the development of gastric secretory mucosal atrophy resulting in achlorhydria and loss of pepsin secretion in a 63-year-old woman with the zollinger-ellison syndrome. reduced secretion began soon after starting treatment with omeprazole, and achlorhydria became complete 6 months later. the patient remains well with normal endoscopy results and is achlorhydric 4 years after the ... | 1991 | 1796940 |
| helicobacter pylori and gastric carcinoma. | 1991 | 1796961 | |
| [helicobacter pylori colonization of the gastric mucosa in rheumatic patients]. | this study examines whether infections with helicobacter pylori are more frequent in patients suffering from rheumatoid arthritis than in patients with non-inflammatory rheumatic diseases. the study furthermore examines whether the colonisation by h. pylori is favoured by antiphlogistic-antirheumatic treatment. for this purpose gastric biopsies obtained by endoscopy from 123 patients were histologically evaluated for the presence of h. pylori. 85 patients with rheumatoid arthritis were compared ... | 1991 | 1771932 |
| inhibition of helicobacter pylori colonization by sulfated gastric mucin. | the role of human gastric mucin in mucosal protection against helicobacter pylori colonization was investigated. h. pylori cells were incubated with purified intact mucin or its acidic fractions and then examined for their inhibitory capacity of h. pylori attachment to erythrocytes. titration data established that the inhibitory activity of mucin was associated with its acidic component as the fraction enriched in sialic acid and sulfate showed 16-fold higher inhibitory titer than that of the in ... | 1991 | 1799374 |
| [the contribution of endoscopy in the diagnosis of esophago-gastro-duodenal disorders in a tropical milieu. experience in benin with 930 examinations]. | the authors analyse the results of esophago-gastro-duodenal fibroscopy in 930 symptomatic patients. ninety one per cent of them had lesions. inflammatory pathology was predominant: esophagitis, gastritis and duodenitis were seen in 21.5%, 47% and 29.08% respectively of the patients investigated. gastritis accompanied 75.13% of cases of esophagitis and 76.4% of duodenitis, and was associated with the demonstration of the presence of helicobater pylori in gastric biopsies in 56.41% of patients wit ... | 1991 | 1772237 |
| evaluation of culture media and antimicrobial susceptibility of helicobacter pylori. | isolation of helicobacter pylori on artificial culture is hampered by the lack of reliable and cheap media. in this study, three different types of culture media were evaluated for isolation of h. pylori from clinical specimens. these media included: modified thayer-martin (mtm), skirrow's campylobacter agar and chocolate agar. modified thayer-martin agar was superior in isolation to others with an isolation rate of 47% (31/66). the size of colonies on this media were larger and clearly defined. ... | 1991 | 1800079 |
| simplified single sample 13carbon urea breath test for helicobacter pylori: comparison with histology, culture, and elisa serology. | there is no ideal method for detecting helicobacter pylori. the 'standard' 13carbon urea breath test (13c-ubt), which involves collecting eight to 15 breath samples and subsequent costly analysis, was modified by pooling 21 samples of expired breath taken at five minute intervals for 40 minutes into a collecting bag, from which a single 20 ml aliquot was taken and analysed by mass spectrometry. this test was evaluated on 50 patients after routine upper gastrointestinal endoscopy, and results wer ... | 1991 | 1773948 |
| antibacterial activity of cefpodoxime in comparison with cefixime, cefdinir, cefetamet, ceftibuten, loracarbef, cefprozil, bay 3522, cefuroxime, cefaclor and cefadroxil. | the new oral cephalosporins cefpodoxime, cefixime, cefdinir, cefetamet and ceftibuten demonstrate enhanced activity against enterobacteriaceae susceptible to the established compounds as well (e.g. cefuroxime, cefaclor, cefadroxil). in addition, cefpodoxime, cefixime, cefdinir, cefetamet and ceftibuten include in their spectrum species hitherto resistant to oral cephalosporins (proteus vulgaris, providencia spp., yersinia enterocolitica). besides, the majority of these compounds demonstrate rele ... | 1991 | 1800377 |
| the simplified 13c-urea breath test--one point analysis for detection of helicobacter pylori infection. | a 13c-urea breath test for detection of helicobacter pylori infection was validated in 306 patients. breath samples (four, two or one) were taken at various time points within 30 minutes after a motility inhibiting liquid test meal with citric acid followed by 75 mg of 13c-urea. the 13co2/12 co2-ratio (delta-value) was measured using isotope ratio mass spectrometry and the recovery of tracer in the exhaled breath was calculated (ubt-value). in 172 patients a comparison of established reference m ... | 1991 | 1771933 |
| the role of omeprazole (40 mg) in the treatment of gastric helicobacter pylori infection. | the efficacy of omeprazole in the elimination of helicobacter pylori was investigated in a prospective randomized-controlled trial. 50 patients with upper gastrointestinal symptoms and chronic active h. pylori-associated gastritis were allocated to one of the following four therapeutic schedules: 1) omeprazole 40 mg/d for 4 weeks (n = 13); 2) bismuth subsalicylate (bss) 3 x 600 mg for 4 weeks (n = 12); 3) omeprazole plus bss for 4 weeks (n = 13); 4) triple therapy (bss for 4 weeks, amoxicillin 3 ... | 1991 | 1771934 |
| [the "sydney system": a consensus approach to gastritis. is a new "classification" necessary?]. | 1991 | 1783247 | |
| susceptibility of helicobacter pylori to metronidazole. | 1991 | 1802703 | |
| helicobacter pylori and gastric premalignant conditions. | a hypothetical sequence occurs in the stomach from h. pylori infection to premalignant conditions. this sequence is characterized by several well documented steps. first, the h. pylori infection seems to be the main course of chronic gastritis, and is seen to be associated with gastritis at least in 80% of the cases. second, chronic gastritis tends to slowly progress to atrophy and intestinal metaplasia of the underlying mucosa in a great proportion of affected subjects, this progression of chro ... | 1991 | 1803836 |
| [the role of serology in the diagnosis of helicobacter (campylobacter) pylori infection]. | the purpose of the communication is to review the different aspects of the helicobacter (campylobacter) pylori infection. the first part of the communication is devoted to the description of the different gastric pathologies induced by the helicobacter pylori infection and to the different methods used for the detection of this infection. today a consensus assesses a causal role to helicobacter pylori in the development of chronic active gastritis (or type b gastritis), in the pathogenesis of du ... | 1991 | 1803838 |
| [helicobacter pylori and erosive lesions of the gastric mucosa in cirrhosis]. | 1991 | 1783258 | |
| characterization of a plasmid from helicobacter pylori encoding a replication protein common to plasmids in gram-positive bacteria. | a 1.5 kb cryptic plasmid was isolated from helicobacter pylori. low-stringency hybridization analysis using this plasmid as a dna probe revealed base sequence homology with other plasmids in this species. nucleotide sequence analysis identified an open reading frame encoding a putative polypeptide of 25 kda. this protein showed marked amino acid sequence similarity to replication-initiation proteins commonly found in small plasmids endogenous to gram-positive bacteria which replicate by the 'rol ... | 1991 | 1791753 |
| helicobacter pylori: treatment with combinations of pivampicillin and tripotassium dicitrato bismuthate. | fifty helicobacter pylori- (h. pylori) positive patients entered an open study and were assigned to one of four treatment regimens comprising: pivampicillin (500 mg b.d.) for 2 weeks +/- tripotassium dicitrato bismuthate (tablet or liquid form) for one month. the 14c-urea breath test was used to evaluate clearance (negative at the end of treatment) and eradication (negative at 1 month post-treatment) of h. pylori. clearance rates were 20% (2/10) after pivampicillin alone, 86% (12/14) after tripo ... | 1991 | 1793785 |
| helicobacter pylori, smoking and gastroduodenitis. | there is epidemiological evidence of an association between cigarette smoking and gastritis. to find out whether the reason for this might be related to the presence of helicobacter pylori, biopsies were taken from the gastric corpus and antrum and from the duodenal bulb in 106 consecutive patients referred for oesophagogastroduodenoscopy because of epigastric pain. patients with ulcer disease or cancer were excluded. the biopsy specimens were cultured for h. pylori and examined histologically f ... | 1991 | 1797597 |
| enzyme-linked immunosorbent assay for detection of immunoglobulin g antibody against helicobacter pylori. | eight strains of sonicated helicobacter pylori (h. pylori) were pooled as group antigen to detect the serum igg antibody to h. pylori in patients with various gastroduodenal diseases and subjects at health check-up. the enzyme-linked immunosorbent assay method used had a sensitivity of 94%, a specificity of 87%, and a positive predictive value of 96%. the prevalence of serum igg antibody to h. pylori was 19.0% in patients with type a gastritis, 76.0% in patients with type b gastritis, 91.5% in d ... | 1991 | 1800030 |
| enhanced clearing of helicobacter pylori after omeprazole plus roxithromycin treatment. | the in vitro antibacterial activity of omeprazole against eight strains of helicobacter pylori was evaluated. minimum inhibitory concentration (mic) values were 32 micrograms/ml and 64 micrograms/ml (mic50 and mic90 respectively). we performed a randomized single blind study comparing the efficacy of omeprazole alone (for 4 weeks) or combined with roxithromycin (for 2 weeks) in the treatment of duodenal ulcer and chronic active gastritis associated with h. pylori infection, h. pylori was eradica ... | 1991 | 1804757 |
| [development of gentamicin sulfate sustained release tablet remaining-floating in stomach]. | gentamicin sulfate sustained-release tablet remaining-floating in stomach (g-hbs) was developed based on the hydrodynamically balanced system. the dissolution rate of g-hbs was determined by rotary basket method (100 r/min, 37 +/- 0.5 degrees c, 0.1 mol/l hcl). the release characteristics of g-hbs showed basically first order kinetics with the dissolution rate constant (kr) of 0.3992 h-1. the mean dissolution time (mdt) of g-hbs was 2.53 h-1. the density of g-hbs was found to have no significant ... | 1991 | 1805513 |
| [antibodies against helicobacter pylori in gastroenterology personnel, patients and the healthy population]. | we have studied the prevalence of igg antibodies to h. pylori in gastroenterology personnel, patients and healthy blood donors to determinate if there is a presumable high risk of infection among the first group, frequently at risk of exposure to gastrointestinal secretions. the positive percentage of sera in the gastroenterology personnel was 30.4% and in the healthy control group (mean age 35.8 years) was 38.5% (p = 0.620). in the patient group, the rate of positive results was 90% and in thei ... | 1991 | 1805887 |
| [the role of helicobacter pylori in ulcer disease]. | 1991 | 1808886 | |
| helicobacter pylori in barrett's esophagus. | barrett's esophagus is an anatomicoclinical state in which, due to the prolonged action of gastroesophageal reflux, the squamous epithelium is replaced by columnar epithelium. helicobacter pylori has been implicated in the pathogenesis of various gastrointestinal disorders and has occasionally been observed in barrett's esophagus. the aim of this study is to determine the incidence of h. pylori in barrett's esophagus and try to establish its role in the pathogenesis of this disorder. h. pylori w ... | 1991 | 1810538 |
| flocculation of venereal disease research laboratory reagent by helicobacter pylori. | helicobacter pylori strains flocculated with venereal disease research laboratory (vdrl) reagent in a glass slide test. other pathogenic bacterial and fungal strains were nonreactive. the specific vdrl reaction property of helicobacter pylori indicates an affinity of the cells for lipoidal substances, and can be used as a diagnostic aid for species identification. | 1991 | 1810734 |
| [campylobacter pylori gastroduodenitis in children with juvenile rheumatoid arthritis]. | clinico-morphological study of the gastroduodenal system and also morphometric investigations of the degree of gastroduodenitis activity and the condition of the local immune system were made in 30 children aged from 4 to 15 years with juvenile rheumatoid arthritis (jra). microbiological, histological and electron microscopic methods for revealing campylobacter pylori (cp) were used. interrelationship between various clinical manifestations of jra with the nature of gastroduodenal system affecti ... | 1991 | 1812557 |
| helicobacter pylori; histological and cultural correlation in chronic gastritis. | seventy seven antral biopsies were collected from patients attending endoscopy clinic at king khalid university hospital, riyadh, saudi arabia during a period of six months between december 1988 to may 1989. of these 69 (89.6%) showed chronic gastritis as well as helicobacter-like organisms (hlos) in the biopsy specimens while 63 (81.8%) of biopsies grew helicobacter pylori on culture. these findings indicate a good correlation between the histological diagnosis of chronic gastritis and isolatio ... | 1991 | 1814029 |
| [helicobacter pylori: identification and correlation between its presence and the histological modification of the mucous membrane in the course of duodenal ulcer and chronic gastritis]. | 1991 | 1814511 | |
| helicobacter pylori infection in dyspeptic patients. | 1991 | 1814886 | |
| anti-helicobacter pylori igg levels in abattoir workers. | the aim of our study was to detect antibodies against helicobacter pylori (h. pylori) in abattoir workers whose activity was variable (pig, poultry-carcasses, poultry-intestinal organs treatment). an adsorption of all sera with h. pylori and campylobacter species known to be ubiquitous and responsible for zoonosis was included in the elisa reaction to eliminate possible cross-reactions between these species. statistically higher specific titres of igg antibodies against h. pylori were observed i ... | 1991 | 1816012 |
| h. pylori and gastroduodenal disease. | 1991 | 1800977 | |
| prevalence of campylobacter pylori in non-ulcerative dyspepsia. | endoscopic biopsies were taken from the gastric antral mucosa, in 150 cases of non-ulcerative dyspepsia at the gastroscopic clinic, dist. hospital, belgaum. spiral or curved bacilli, were demonstrated in specimens from 99 patients. the histologic demonstration of the organism by warthin starry stain (66%) was superior to haematoxylin and eosin (47.33%), urease test (42%) and gram's stain (35.33%). there was a strong association between c pyloridis in the gastric mucosa and histologically defined ... | 1991 | 1818028 |
| [the intestinal microflora and acid-forming function of the stomach in peptic ulcer patients with helicobacter pylori bacteriosis]. | seventeen duodenal ulcer patients were examined. h. pylori were detected in all the patients by histological and bacteriological methods. changes in the enteric microflora, manifested by a decrease in the number of lacto- and bifidobacteria and by an increased level of opportunistic microflora, were established. cimetidine treatment and the suppression of the acid-producing function of the stomach augmented enteric dysbacteriosis and h. pylori contamination of the gastric and duodenal mucosa. | 1991 | 1801479 |
| diagnosis and distribution of helicobacter pylori in the gastric mucosa of symptomatic children. | 1. the demonstration of the association of h. pylori with gastritis and peptic ulcer has been of increasing interest to gastroenterologists, microbiologists, and histopathologists. 2. in this study, the presence of h. pylori in the gastric mucosa of children was investigated by culture, preformed urease test, and carbolfuchsin staining of biopsy smears. 3. the organism was detected in 44.9% of the children studied, and found to be distributed equally on the antral and fundic mucosa. 4. compared ... | 1991 | 1823229 |
| use of ampicillin plus ranitidine for helicobacter pylori gastritis. | 1. helicobacter pylori (formerly campylobacter pylori) is now recognized as an etiological factor in gastritis and duodenal ulcers and probably also gastric ulcers. eradication of the bacteria is fundamental to avoid ulcer relapse. although bismuth salts have been shown to be effective for treatment, they are not commercially available in brazil. 2. we report an attempt to treat patients with helicobacter pylori-associated gastritis with ampicillin (1000 mg twice daily for one month) and compare ... | 1991 | 1823272 |
| antral helicobacter pylori-like organisms in different states of gastric acid secretion. | the frequency of helicobacter pylori (h.p.) infestation in antral mucosa and the presence of gastritis were investigated in different states of gastric acid secretion. biopsies were stained by the warthin-starry technique and hematoxylin-eosin. antral h.p. was found in similar frequencies in zollinger-ellison syndrome (n = 17; profound acid hypersecretion, associated with duodenal ulcer disease in most cases) and the same number of age-matched controls (35% in each group) whereas h.p. could be d ... | 1991 | 1800186 |
| ulcer relapse rates following initial treatment with bismuth subnitrate as compared with cimetidine respectively. | as part of an open clinical trial, 18 out of 23 (78%) patients were treated with bismuth subnitrate (3 x 700 mg/d) and 15 out of 25 (60%) patients were treated with cimetidine (1 x 800 mg/d) to cure peptic ulcers linked with h. pylori, as ascertained following an endoscopic examination. all patients underwent continued observation after complete healing on completion of four weeks of acute treatment. in order to determine the effect of the initial treatment on the rate of relapse, all patients w ... | 1991 | 1800390 |
| the prevalence of helicobacter pylori infection in the peoples republic of china. | meta-analysis on data from 16 (two volunteer and 14 endoscopic) studies ahs been performed to investigate the prevalence of helicobacter pylori infection in the stomachs of individuals within the peoples republic of china. in this survey covering 2216 cases (89 volunteers and 2127 endoscopy patients), the incidence of h. pylori infection in 15- to 22-yr-old healthy volunteers, and in 13- to 88-yr-old symptomatic patients undergoing gastroscopy was 49.4% and 64.5%, respectively. the frequency of ... | 1991 | 1826406 |
| inhibition of gastric mucosal laminin receptor by helicobacter pylori lipopolysaccharide. | laminin receptor was isolated from gastric epithelial cell membrane by the procedure involving membrane solubilization with octylglucoside followed by affinity chromatography on laminin-coupled sepharose. the receptor protein, eluted from the matrix with cation-free edta buffer, yielded on sds-page a single 67kda band. after radioiodination, the protein was incorporated into liposomes which displayed specific affinity toward the laminin-coated surface. the binding of liposomal receptor to the la ... | 1991 | 1827258 |
| gamma delta t cell receptor-positive cells of the human gastrointestinal mucosa: occurrence and v region gene expression in heliobacter pylori-associated gastritis, coeliac disease and inflammatory bowel disease. | t cells expressing the gamma delta heterodimer of the t cell receptor (tcr) were studied with respect to their occurrence and expression of gamma delta tcr variable region (v) genes in the normal gastrointestinal mucosa and in a variety of inflammatory conditions. in controls, gamma delta tcr+ cells were a minority population confined to the epithelial compartment of stomach, small bowel and colonic mucosae. unlike in the periphery, gastro-intestinal gamma delta tcr+ intraepithelial lymphocytes ... | 1991 | 1828397 |
| [esaprazole vs sulglicotide in the treatment of dyspeptic patients with chronic superficial gastritis of the antrum]. | fifty dyspeptic patients with histologically proven chronic superficial antral gastritis were treated for 6 weeks, in a randomized single-blind study, with esaprazole (450 mg bid) or sulglicotide (200 mg tid). both drugs significantly improved the symptomatic score after 3 and 6 weeks (p less than 0.01), and the percentual rate of improvement was similar in the two groups studied. similarly, both treatments significantly reduced the inflammation of gastric mucosa. drugs were ineffective in clear ... | 1991 | 1828408 |
| mucosal tumour necrosis factor alpha and interleukin-6 in patients with helicobacter pylori associated gastritis. | the production of tumour necrosis factor alpha (tnf alpha) and interleukin-6 by human antral mucosa during short term culture in vitro has been measured by enzyme linked immunosorbent assay. tnf alpha and interleukin-6 concentrations in culture supernatants were significantly greater (p less than 0.001) in patients infected with helicobacter pylori, all of whom had chronic gastritis, than in patients who were h pylori negative with histologically normal gastric mucosa. among h pylori colonised p ... | 1991 | 1773951 |
| combined activity of trospectomycin and colloidal bismuth subcitrate against helicobacter pylori in vitro. | the combined activities of trospectomycin, a spectinomycin analogue, and colloidal bismuth subcitrate against helicobacter pylori were investigated, the agar dilution method being employed. forty-seven strains of h. pylori were examined. an additive effect was observed in 89%, and a synergistic interaction in 11% of the isolates. there was no antagonism observed. the mic50 of trospectomycin against h. pylori was 2 mg/l; the mic ranged from 0.5 to 4 mg/l. | 1991 | 1832417 |
| gastric colonization of the ferret with helicobacter species: natural and experimental infections. | helicobacter mustelae, isolated from the stomachs of adult ferrets, appears to have a world-wide distribution. ferrets are colonized with h. mustelae at a young age, usually 5-6 weeks; in our experience 100% of adult ferrets are colonized in both the antrum and the fundus. gastric infection correlates with elevation of serum igg antibodies to h. mustelae. in the oxyntic mucosa the presence of superficial gastritis coincides closely with the presence of h. mustelae. in the distal antrum the organ ... | 1991 | 1833810 |
| mechnisms of injury and sequelae of helicobacter pylori infection. concluding commentary--the basic scientist's viewpoint. | 1991 | 1775919 | |
| mechanisms of injury and sequelae of helicobacter pylori infection. concluding commentary--the gastroenterologist's viewpoint. | 1991 | 1775920 | |
| helicobacter pylori infection and inflammation. | helicobacter pylori infection and chronic active gastritis are inextricably linked, and this organism is almost certainly responsible for inducing the resulting inflammatory changes. acute ingestion studies have confirmed that h. pylori infection causes acute gastritis, and the progression to chronic gastritis has been documented. duodenitis and h. pylori infection often occur concurrently, but colonization is restricted to those with significant gastric metaplasia. the association between h. py ... | 1991 | 1775921 |
| virulence factors of helicobacter pylori. | helicobacter pylori can be considered a very successful organism effectively colonizing the majority of the world's population. although various disease states associated with this infection have been described, the mechanisms of pathogenicity remain unknown. the easiest virulence factors to identify are those enabling the organism to colonize the hazardous microenvironment of the gastric epithelium, survive at this site, and multiply sufficiently for transmission to a new host. the factors iden ... | 1991 | 1775922 |
| non-ulcer dyspepsia and the dilemma posed to its management. | dyspepsia is one of the most common ailment that is managed by general practitioners and gastroenterologists worldwide and particularly so in tropical africa. non-ulcer dyspepsia can be defined as the presence of classic ulcer symptoms or any combination of burning, bloating, indigestion or other abdominal symptoms which only sometimes have a relation to food intake with out any radiological or endoscopic evidence of peptic ulceration. compared to peptic ulcer disease, the literature on non-ulce ... | 1991 | 1841450 |
| inhibitory effect of natural honey on helicobacter pylori. | honey is widely used in folk-medicine throughout the world. however, it has a limited use in modern medicine due to lack of scientific support. based on some recent reports, an in vitro study was undertaken to evaluate its antibacterial activity on helicobacter pylori and a few other pathogenic organisms. all isolates of h. pylori were inhibited by 20 per cent of honey. most of the other bacteria examined (including both gram-positive and gram-negative) were also inhibited at concentrations of 2 ... | 1991 | 1841451 |
| helicobacter pylori is not a co-carcinogen in n-methyl-n'-nitro-n-nitrosoguanidine-induced rat gastric carcinogenesis. | helicobacter pylori was implicated in gastric carcinogenesis through the induction of metaplasia of the gastric mucosa. in this experiment a co-carcinogenic effect of h. pylori on chemically induced gastric carcinogenesis was examined. wistar wky male rats received drinking water containing 50 mg/l of n-methyl-n'-nitro-n-nitrosoguanidine (mnng), and intragastric administration of 10(6) to 10(8) colony forming unit of h. pylori thrice a week for 40 weeks. thus, 3 groups were assigned as group i; ... | 1991 | 1843054 |
| helicobacter pylori urease: properties and role in pathogenesis. | urease (urea amidohydrolase, ec 3.5.1.5) catalyzes the hydrolysis of urea to yield ammonia and carbon dioxide. research on this enzyme has gained momentum since the discovery of helicobacter pylori as a causative agent of human gastritis. the remarkably high urease activity of each organism has served as the basis of diagnostic tests for the presence of the organism in the urease biopsy test and urea breath test. urease undoubtedly plays a central role in h. pylori pathogenesis. hydrolysis of ur ... | 1991 | 1775923 |
| diagnosis of helicobacter pylori: comparison of an urease test, histological visualization of curved bacteria and culture. | helicobacter pylori was investigated in 189 patients for culture, microscopic visualization of campylobacter-like organisms (clo) and a ten minute urease test. in 136 (72%) the bacteria was isolated, and in 98 of them clo were histologically detected. specificity, sensitivity, positive and negative predictive values of microscopic visualization of clo were: 0.77, 0.73, 0.97 and 0.51, respectively; 98 culture-positive patients were urease test positive. specificity, sensitivity, positive and nega ... | 1991 | 1843403 |
| [incidence of helicobacter pylori in barrett esophagus]. | in barrett's esophagus the normal squamous epithelium of the mucosa is replaced by columnar epithelium. in this study, we evaluated the incidence of helicobacter pylori in 28 patients with barrett's esophagus. in 11 patients (39%) h. pylori was present and all of them had the bacteria in the gastric antrum. from the 17 patients without h. pylori in the barrett's mucosa, in 4 (22%) the bacteria was present in the gastric antrum. in conclusion, h. pylori infects the esophagus only when the esophag ... | 1991 | 1843931 |
| development of epidemiological method for the helicobacter pylori by polymerase chain reaction. | the polymerase chain reaction was used to develop a method for the detection of helicobacter pylori, a causative agent of gastritis, as well as for the elucidation of its mode of transmission. a genomic library of helicobacter pylori dna in escherichia coli jm109 was constructed by cloning hind iii-digested dna fragments into plasmid vector puc18. the nucleotide sequences from seven recombinant clones were determined and five sets of oligonucleotide primers were synthesized on the basis of the s ... | 1991 | 1844643 |
| mucolytic effects of helicobacter pylori. | the mechanisms associated with colonization of human gastroduodenal mucosa by helicobacter pylori remain unclear. to colonize gastric-type epithelium h. pylori must enter the gastric lumen, resist damage by all bactericidal factors operating within the acidic gastric milieu, penetrate the mucus gel despite highly viscous and hydrophobic properties of the mucus layer, and, finally, secure optimal conditions for its further multiplication. since the h. pylori microorganism has been seen freely spr ... | 1991 | 1775924 |
| [occurrence of campylobacter pylori in gastric mucosa and selected parameters of cell-mediated immunity in patients with duodenal ulcer and individuals with non-ulcerative dyspepsia]. | the study was aimed at investigating a relationship between campylobacter pylori infection in the gastric mucosa and selected parameters of cell-mediated immunity in patients with duodenal ulcer and the individuals with non-ulcerative dyspepsia. a relationship between campylobacter pylori and gastritis has also been studied. endoscopic and immunological tests were carried out in the group of 45 patients, including 14 patients with duodenal ulcer and 29 with non-ulcerative dyspepsia. specimens of ... | 1991 | 1845737 |
| interactions between helicobacter pylori and the local mucosal immune system. | the recognition that helicobacter pylori is associated with an array of gastric disorders immediately raises several issues with regard to the role of the local immune system. the belief that the harsh gastric environment limits or prevents infection has perhaps dismissed studies into the immunology of the stomach as a low priority. now, in combination with our understanding of local immune reactivity in pernicious anaemia, an interest in defining the contribution of the immune response in the p ... | 1991 | 1775925 |
| possible mechanisms and mediators of gastritis associated with helicobacter pylori infection. | there is a growing body of evidence suggesting that helicobacter pylori plays a pathogenic role in gastric and duodenal ulceration. a strong association between infection with this organism and the presence of active chronic gastritis in the antrum has been documented. however, the mechanism through which this gastritis and the associated degenerative changes in the mucosa are produced is not fully understood. it is possible that the bacterium itself produces chemotactic factors that recruit gra ... | 1991 | 1775926 |
| helicobacter pylori and gastric acid secretion: the ulcer link? | helicobacter pylori is a recognized cause of chronic active gastritis and is frequently associated with peptic ulcer disease, but its effect on acid secretion is unclear. transient hypochlorhydria occurs with acute infections. despite the theoretical possibility of an increase in parietal cell mass or a response to stimulation occurring secondary to the associated hypergastrinaemia observed with h. pylori, no consistent increase in basal, pentagastrin-stimulated acid secretion or 24-h intragastr ... | 1991 | 1775927 |
| a comparison of symptoms between non-ulcer dyspepsia patients positive and negative for helicobacter pylori. | the role of helicobacter pylori infection in the symptom complex associated with non-ulcer dyspepsia is uncertain, despite the presence of the organism in a high proportion of these patients. in order to exclude physician bias in history taking, 18 patients (9 female) diagnosed as non-ulcer dyspepsia, after endoscopy and gallbladder ultrasonography, underwent computer interrogation using the glasgow diagnostic system for dyspepsia (gladys). five antral and 3 fundal endoscopic biopsies from these ... | 1991 | 1853492 |
| helicobacter pylori--some what, why, and how morphologic issues. | this paper questions, and attempts to answer or speculate on, some of the morphologic questions about helicobacter pylori in the stomach and duodenum. these include whether h. pylori can survive intact through the entire intestine, why organisms are found between rather than over the entire cells, why pedestals are relatively infrequent, possible advantages of attachment rather than a luminal existence, the nature of the inflammatory cascade from chronic inflammation to local erosion, possible m ... | 1991 | 1775928 |
| effect of triple therapy (antibiotics plus bismuth) on duodenal ulcer healing. a randomized controlled trial. | to determine whether antimicrobial therapy for helicobacter pylori infection accelerates the healing of duodenal ulcers. | 1991 | 1854110 |
| helicobacter and hypergastrinemia: the quisling option. | helicobacter infection of the gastric antrum is linked to the development of duodenal ulcer. a key element could be the associated hypergastrinemia. this brief commentary seeks answers to the following questions: 1) does hypergastrinemia occur? 2) how does it occur? and 3) does it matter? | 1991 | 1775929 |
| [secretory immunoglobulin a and pyloric helicobacteriosis in patients with duodenal ulcer]. | 57 patients with duodenum ulcer were examined. secretory immunoglobulin a (siga) was determined by an immunofluorescent method in the gastric and duodenum mucosa depending on the population size of pyloric helicobacter (hb). the frequency of siga detection in the gastric mucosa depends on the hb population size: when it is considerable siga was not detected in 41% cases. siga was detected in the gastric mucosa without pathological lesions in 85% cases, in atrophic gastritis in 70% and in superfi ... | 1991 | 1854274 |
| helicobacter pylori infection and gastric cancer. | 1991 | 1855030 | |
| helicobacter pylori infection and duodenal ulcer. | 1991 | 1855031 | |
| exposure to n-nitrosamines and other risk factors for gastric cancer in costa rican children. | the hypothesis that endogenous chemical nitrosation in the normal stomach in early life could play a crucial role in inducing chronic atrophic gastritis/intestinal metaplasia in later life was tested by applying the n-nitrosoproline (npro) test to 12-h urine samples from about 50 children (aged 8-14 years) living in high- and low-risk areas for stomach cancer. the median values of npro and the sum of four nitrosamino acids analysed were 0.28-0.84 micrograms/12 h and 0.75-1.75 micrograms/12 h, re ... | 1991 | 1855842 |
| the etiology of gastric cancer. | we review recent evidence concerning risk factors for gastric cancer. an overview of analytical studies shows convincing evidence of a protective effect of fruit and vegetables. the specific protective constituents have not been firmly established, but micronutrients, especially ascorbic acid, are probably of importance. other dietary factors that show a consistent pattern of effect in different studies are the moderate risks associated with high intake of preserved foods and salt. evidence also ... | 1991 | 1855854 |