Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| summary of the guidelines for preventing opportunistic infections among hematopoietic stem cell transplant recipients. | this article contains highlights of "guidelines for preventing opportunistic infections among hematopoietic stem cell transplant recipients: recommendations of the cdc, the infectious diseases society of america, and the american society of blood and marrow transplantation," which was published in the morbidity and mortality weekly report. there are sections on the prevention of bacterial, viral, fungal, protozoal, and helminth infections and on hospital infection control, strategies for safe li ... | 2001 | 11418871 |
| [respiratory infections during chemotherapy-induced aplasia]. | damage to local and systemic host defenses of the lung makes the immunocompromised patient vulnerable to inhaled microorganisms. when a pulmonary infiltrate occurs, the array of possibilities is very large including conventional and opportunistic agents. the type of underlying disease and its associated immunodeficiency allow a high degree of accurate pathogen prediction. neutropenia is associated with gram-negative bacilli pneumonia. prolonged neutropenia increases the risk of invasive aspergil ... | 2001 | 11424709 |
| a meta-analysis of salvage therapy for pneumocystis carinii pneumonia. | to determine the relative efficacies of alternative antipneumocystis agents in human immunodeficiency virus (hiv)-infected patients with pneumocystis carinii pneumonia unresponsive to primary drug treatment with a combination product of trimethoprim and sulfamethoxazole or parenteral pentamidine. | 2001 | 11427101 |
| pneumocystis carinii carriage among cystic fibrosis patients, as detected by nested pcr. | a total of 137 sputa from 95 consecutive cystic fibrosis (cf) patients undergoing routine bacteriological surveillance were analyzed for pneumocystis carinii colonization using nested pcr. seven of 95 patients (7.4%) were pcr positive, suggesting that p. carinii carriage may exist among cf patients due to their underlying pulmonary disease. | 2001 | 11427604 |
| isolated pneumocystis carinii infection of adrenal glands causing addison's disease in a non-immunocompromised adult. | pneumocystis carinii is primarily an opportunistic pathogen infecting patients with aids and other immunocompromised patients, and ordinarily does not affect immunocompetent persons. we report isolated p. carinii infection of bilateral adrenal glands in a non-immunocompromised adult male, leading to fatal addisonian crisis. diagnosis of p. carinii was established on the basis of cytopathology and microbiological tests, using conventional staining techniques and direct immunofluorescence on ultra ... | 2001 | 11478273 |
| cavitary lung disease in aids: etiologies and correlation with immune status. | to investigate the etiology and differential features of cavitary lung disease in patients with acquired immune deficiency syndrome (aids), chest computed tomography (ct) records from a 2-year period were reviewed to identify all human immunodeficiency virus (hiv)-positive patients with cavitary lung disease. medical records were reviewed for the documentation of specific causes of lung cavitation and the cd4 count at the time of imaging. of 25 hiv-positive patients with cavitary lung disease, 2 ... | 2001 | 11483162 |
| infectious complications among 620 consecutive heart transplant patients at stanford university medical center. | a total of 1073 infectious episodes (ies) that occurred in 620 consecutive heart transplantation patients at stanford medical center between 16 december 1980 and 30 june 1996 were reviewed. infectious complications were a major cause of morbidity and mortality, second only to rejection as the cause of early deaths and the most common cause of late deaths. of the ies, 468 (43.6%) were caused by bacteria, 447 (41.7%) by viruses, 109 (10.2%) by fungi, 43 (4.0%) by pneumocystis carinii, and 6 (0.6%) ... | 2001 | 11486285 |
| diagnostic yield of bronchoalveolar lavage following renal transplantation. | organ transplant recipients are at high risk of infectious pulmonary complications. in this retrospective study, the diagnostic yield of bronchoalveolar lavage (bal) was evaluated in renal transplant recipients. the results were analysed in special regard to the clinical presentation of pulmonary infections and the possible impact of new immunosuppressive agents. over a 5-year period 91 bal were performed in 71 renal transplant recipients. microorganisms were isolated from 69% of bal (63/91): ba ... | 2001 | 11429033 |
| the spectrum of pulmonary infections in cancer patients. | the lung is a common site of infection in patients with cancer. the spectrum of pulmonary infection depends on the underlying immunologic deficit or deficits. in neutropenic patients, gram-negative bacterial infections predominate early, whereas fungal infections (aspergillus, zygomycetes, fusarium species) are common if neutropenia persists. in patients with impaired cellular immunity, viral infections (cytomegalovirus, other herpes viruses) predominate and may coexist with bacterial (legionell ... | 2001 | 11429477 |
| [opportunistic pneumonia after kidney transplantation]. | this study was conducted to evaluate clinical features at the onset of pneumonia and the usefulness of methods for diagnosing pneumonia in patients who have undergone kidney transplantation. from january 1990 to december 1998. 174 kidney transplantations were performed, and were followed by 22 cases of pneumonia. of the 22 pneumonia patients, 16 were male and 6 were female. the median age of the 22 patients was 37.2 +/- 13.3 years. all the patients received cyclosporin a and corticosteroids. in ... | 2001 | 11431908 |
| [common variable immunodeficiency. review]. | common variable immunodeficiency (cvi) is a primary immunodeficiency characterized by deficient antibody production. the cause of this immunodeficiency is unknown; several in vitro studies have revealed a significant number of alterations that could explain the hypogammaglobulinemia present in this syndrome. among those described are primary b cell alterations, numerical and functional t cell abnormalities, and defects in the interaction between accessory cells. the alteration typical of cvi is ... | 2001 | 11434884 |
| prophylaxis with trimethoprim-sulfamethoxazole for human immunodeficiency virus-infected patients: impact on risk for infectious diseases. | trimethoprim-sulfamethoxazole (tmp-smz) is widely prescribed as prophylaxis for pneumocystis carinii pneumonia (pcp) in human immunodeficiency virus (hiv)-infected persons. its efficacy against other infections has not been thoroughly evaluated. to compare the risk for infectious diseases for persons who were prescribed tmp-smz with that for patients who were not prescribed tmp-smz, we examined data collected from the medical records of hiv-infected patients (january 1990 through september 1999) ... | 2001 | 11438910 |
| comments on pcr-rflp as an original technique to detect point mutations in the pneumocystis carinii dhps gene. | 2001 | 11440235 | |
| the etiology of community-acquired pneumonia at an urban public hospital: influence of human immunodeficiency virus infection and initial severity of illness. | in a prospective study, the etiology of community-acquired pneumonia (cap) was investigated among consecutive patients admitted to an academic, urban public hospital in seattle. the study population was uniquely young, was predominantly male, and had high rates of homelessness, cigarette smoking, alcoholism, injection drug use, and human immunodeficiency virus (hiv) infection. leading causes of cap among hiv-negative patients were aspiration, followed by streptococcus pneumoniae, legionella spec ... | 2001 | 11443551 |
| alteration in expression of the rat mitochondrial atpase 6 gene during pneumocystis carinii infection. | pneumocystis carinii causes pneumonia in immunocompromised patients with a high morbidity and mortality rate, but the interaction between this organism and the host cell is not well understood. the purpose of this research was to study the response of host cells to p. carinii infection on a molecular level. | 2001 | 11446902 |
| molecular cloning of the rps0 gene from candida tropicalis. | the saccharomyces cerevisiae rps0 a and b genes encode proteins essential for maturation of the 40s ribosomal subunit precursors. we have isolated a homologue of the rps0 gene from candida tropicalis, which we named ctrps0. the c. tropicalis rps0 encodes a protein of 261 amino acid residues with a predicted molecular weight of 28.65 kda and an isoelectric point of 4.79. ctrps0p displays significant amino acid sequence homology with rps0p from c. albicans, s. cerevisiae, neurospora crassa, schizo ... | 2001 | 11447603 |
| design, synthesis, computational prediction, and biological evaluation of ester soft drugs as inhibitors of dihydrofolate reductase from pneumocystis carinii. | a series of lipophilic soft drugs structurally related to the nonclassical dihydrofolate reductase (dhfr) inhibitors trimetrexate and piritrexim have been designed, synthesized, and evaluated in dhfr assays, with special emphasis on the inhibition of p. carinii dhfr. the best inhibitors, encompassing an ester bond in the bridge connecting the two aromatic systems, were approximately 10 times less potent than trimetrexate and piritrexim. the metabolites were designed to be poor inhibitors. furthe ... | 2001 | 11448221 |
| heimlich valve in the management of pneumothorax in patients with advanced aids. | to review therapeutic strategies in the management of pneumothorax in patients with aids. | 2001 | 11451809 |
| population pharmacokinetics of dapsone in children with human immunodeficiency virus infection. | previous studies of dapsone pharmacokinetics in children have been too small to allow assessment of the relationships between dapsone pharmacokinetic parameters and patient characteristics or markers of efficacy and toxicity. | 2001 | 11452241 |
| could pneumocystis carinii have a role in sudden infant death syndrome? | 2001 | 11454387 | |
| the effect of atovaquone on etoposide pharmacokinetics in children with acute lymphoblastic leukemia. | the use of trimethoprim/sulfamethoxazole in the prevention of pneumocystis carinii pneumonia in patients with acute lymphoblastic leukemia (all) may cause undesirable adverse effects: fungal overgrowth, neutropenia, and drug resistance. a possible alternative is atovaquone, a hydroxynaphthoquinone with anti-pneumocystis carinii activity. however, it is not known if atovaquone alters the disposition or adverse effects of antileukemic drugs. | 2001 | 11459198 |
| [opportunistic episodes in patients infected with the human immunodeficiency virus during the first 6 months of haart]. | we aimed at analysing the incidence and characteristics of opportunistic events (oe) within a few months after starting highly active antiretroviral therapy (haart) in hiv infected patients. | 2001 | 11459574 |
| pneumocystis carinii pneumonia during maintenance treatment of childhood acute lymphoblastic leukemia. | pneumocystis carinii pneumonia (pcp) is a wellknown risk among patients with deficient t-cell function such as children treated for acute lymphoblastic leukemia (all). the purpose of this study was to estimate the risk for pcp during maintenance treatment (mt) to identify patients at risk who could benefit from prophylaxis. | 2001 | 11466718 |
| outcome of cytomegalovirus infections in patients with inflammatory bowel disease. | the aim of this study was to determine the outcome of cytomegalovirus (cmv) infections complicating the course of inflammatory bowel disease (ibd). | 2001 | 11467645 |
| emerging trends in the epidemiology of invasive mycoses in england and wales (1990-9). | invasive fungal infections are becoming an increasing public health problem owing to the growth in numbers of susceptible individuals. despite this, the profile of mycoses remains low and there is no surveillance system specific to fungal infections currently existing in england and wales. we analysed laboratory reports of deep-seated mycoses made to the communicable disease surveillance centre between 1990 and 1999 from england and wales. a substantial rise in candidosis was seen during this pe ... | 2001 | 11467797 |
| [pulmonary involvement in children with aids: clinical study and necropsy of 14 cases]. | to describe clinical, laboratorial, radiological, and histopathological lung findings from necroscopy of aidetic children with pulmonary disease. | 2001 | 11468680 |
| pleural effusions and pneumothoraces in aids. | pneumothorax occurs in 1 to 2% of hospitalized patients with hiv and is associated with 34% mortality. pneumocystis carinii pneumonia and chest radiographic evidence of cysts, pneumatoceles, or bullae are risk factors for spontaneous pneumothorax. tube thoracostomy, pleurodesis, and surgical treatment are usually needed to manage spontaneous pneumothorax in aids. pleural effusion is seen in 7 to 27% of hospitalized patients with hiv infection. its three leading causes are parapneumonic effusions ... | 2001 | 11470975 |
| osteonecrosis in patients infected with human immunodeficiency virus: a case-control study. | to evaluate risk factors for osteonecrosis in human immunodeficiency virus (hiv)-infected patients, demographic and clinical characteristics of case patients (n=17) and control patients (n=34) matched on initial clinic visit date, length of follow-up, and baseline cd4 cell count were compared. case patients were more likely to have received corticosteroids (47.1% vs. 8.8%; matched odds ratio [or], 13.1; 95% confidence interval [ci], 1.6-106), to have had an increase in cd4 cell count from nadir ... | 2001 | 11471113 |
| structural studies on bioactive compounds. 34. design, synthesis, and biological evaluation of triazenyl-substituted pyrimethamine inhibitors of pneumocystis carinii dihydrofolate reductase. | the triazenyl-pyrimethamine derivative 3a (tab), a potent and selective inhibitor of pneumocystis carinii dhfr, was selected as the starting point for a lead optimization study. molecular modeling studies, corroborated by a recent crystal structure determination of the ternary complex of p. carinii dhfr--nadph bound to tab, predicted that modifications to the acetoxy residue of the lead inhibitor could exploit binding opportunities in the vicinity of an active site pocket bounded by residues ile ... | 2001 | 11472209 |
| genetic diversity of pneumocystis carinii isolated from human immunodeficiency virus-positive patients in turin, italy. | by dna sequence analysis we identified two new strain types and five novel sporadic variations among 25 isolates of pneumocystis carinii f. sp. hominis obtained from 19 human immunodeficiency virus-positive patients. of these, 13 were infected with a single strain and 6 were coinfected. fifteen different combination types were identified among the 18 strains for which complete molecular typing was accomplished. | 2001 | 11474032 |
| myoclonus secondary to the concurrent use of trazodone and fluoxetine. | a 39-y-o male with a history of human immunodeficiency virus infection and depression was admitted for diagnosis and treatment of tuberculosis and pneumocystis carinii pneumonia infections. prior to admission, he was on 50 mg trazodone every evening for 2 mo for depression. he was admitted with a 2-w history of fever chills and fatigue and on admission had hand tremors which disappeared at rest. four days post-admission the trazodone dose was increased to 100 mg and 20 mg fluoxetine was initiate ... | 2001 | 11474735 |
| a randomized, double-blind, placebo-controlled study of itraconazole capsules for the prevention of deep fungal infections in immunodeficient patients with hiv infection. | to determine whether systemic or deep fungal infections can be prevented, a double-blind, placebo-controlled, phase iii trial of itraconazole prophylaxis was undertaken in hiv-infected patients. | 2001 | 11737382 |
| pneumocystis carinii pneumonia: a review of current issues in diagnosis and management. | 2001 | 11737389 | |
| pulmonary pathology in patients with aids: an autopsy study from mumbai. | although india has a high prevalence of hiv/aids, the associated pathologies responsible for morbidity have not been evaluated previously in a representative study. hence, an autopsy study was carried out to analyse the spectrum of pulmonary lesions in patients with hiv/aids. | 2001 | 11737408 |
| mutations in dihydropteroate synthase gene of pneumocystis carinii in hiv patients with pneumocystis carinii pneumonia. | the purpose of this study was to determine whether dihydropteroate synthase gene (dhps) mutations were associated with the failure of sulpha/sulphone drugs used as prophylaxis agents in hiv infected patients. results suggested that dhps mutations were significantly associated with failure of anti-pneumocystis carinii sulphone prophylaxis (p=0.031). an increasing number of mutant p. carinii strains have been isolated from patients no longer having prophylaxis. there was no statistically significa ... | 2001 | 11738342 |
| pulmonary manifestations of hiv infection in the era of highly active antiretroviral therapy. | to determine whether the spectrum of hiv-related pulmonary disease seen by a university medical center pulmonary and critical care medicine service has changed since the introduction of highly active antiretroviral therapy (haart). | 2001 | 11742918 |
| germ cell tumors in patients infected by the human immunodeficiency virus. | the objective of this study was to assess the natural history of the two disease courses, patient immune system tolerance, and results of therapy in human immunodeficiency virus (hiv)-infected patients with germ cell tumors (gct). | 2001 | 11745223 |
| flexible bronchoscopy in the diagnosis of pulmonary infiltrates following autologous peripheral stem cell transplantation for advanced breast cancer. | flexible bronchoscopy is an important tool in the diagnosis of pulmonary complications following bone marrow transplantation. however, the value of this procedure in autologous peripheral stem cell transplant (apsct) recipients with pulmonary complications is not well defined. we retrospectively evaluated the diagnostic yield of 27 consecutive bronchoscopies done on 23 apsct recipients following high-dose chemotherapy for breast cancer. fb resulted in a positive diagnosis in 16 cases (59%). bron ... | 2001 | 11753555 |
| a 10-year follow-up study on the health status of heroin addicts based on official registers. | to determine the health status of a cohort of heroin addicts. | 2001 | 11784470 |
| transplantation of highly purified cd34+thy-1+ hematopoietic stem cells in patients with recurrent indolent non-hodgkin's lymphoma. | to evaluate the results of high-dose chemotherapy and transplantation of highly purified "mobilized" peripheral blood cd34+thy-1+ hematopoietic stem cells (hscs) in patients with recurrent indolent non-hodgkin's lymphoma (nhl) or mantle cell lymphoma (mcl). | 2001 | 11787531 |
| pneumocystis carinii granuloma of the optic nerve: a histopathologic case report. | a 30-year-old man under treatment for acute leukemia died of candida sepsis and pneumocystis carinii pneumonia. a small granuloma containing pneumocystis carinii was found in one optic nerve. | 2001 | 11756858 |
| pneumocystis carinii pneumonia in systemic lupus erythematosus: a report of two cases. | patients with systemic lupus erythematosus (sle) have increased susceptibility to infection by pneumocystis carinii, but this condition has rarely been reported in taiwan. here, we describe two cases of patients with sle who developed pneumocystis carinii pneumonia (pcp). the first patient was a 39-year-old woman presenting with fever and dyspnea that had lasted 2 weeks. chest roentgenography disclosed bilateral interstitial and alveolar infiltrates. the second patient was a 22-year-old woman pr ... | 2001 | 11760377 |
| [primary immunodeficiency secondary to zap-70 deficiency]. | the authors present the case of a child with recurrent infections since the age of 4 months, including bilateral pneumonia by pneumocystis carinii and protracted varicella. serum immunoglobulin values (when 10 months old), and b cell values were normal. there was persistent lymphocytic leucocytosis, near absence of cd8+ cells, and an increased cd4/cd8 ratio. the percentage of activated t cells and the expression of hla class i were normal. proliferation, activation and il-2 synthesis studies in ... | 2001 | 11762183 |
| fludarabine and mitoxantrone: effective and well-tolerated salvage therapy in relapsed indolent lymphoproliferative disorders. | prior studies of the combination of fludarabine, mitoxantrone and dexamethasone have yielded high response rates but are associated with a significant risk of opportunistic infections, predominantly pneumocystis carinii pneumonia (pcp) requiring routine prophylaxis. | 2001 | 11762819 |
| [pneumothorax in patients infected by the human immunodeficiency virus]. | patients with hiv who develop pneumothorax have been previously described. pneumocystis carinii pneumonia (pcn) is the leading cause of this complication, but infection by other pulmonary microorganism, inhaled pentamidine therapy and lung invasive manoeuvres have also been associated with pneumothorax in hiv infected patients. | 2001 | 11766281 |
| antibacterial prophylaxis with trimethoprim-sulfamethoxazole during induction treatment for acute lymphoblastic leukemia. | children with acute lymphoblastic leukemia are treated with intensive chemotherapy resulting in profound immuno suppression. therefore treatment with trimethoprim-sulfamethoxazole (tmp-smx) may be used for prophylaxis against infections both with bacteria and pneumocystis carinii in some departments. the use of tmp-smx for prophylaxis during the induction therapy is not uniform in the four departments of pediatric oncology in denmark. this gave us the opportunity to describe the effect of tmp/sm ... | 2001 | 11767129 |
| [a case of pneumocystis carinii pneumonia with pulmonary cysts and increased level of serum kl-6]. | in august, 1999, a 46-year-old man with fever, cough, and dyspnea was admitted to a hospital. on the basis of the clinical and radiographic findings, bacterial pneumonia was suspected. antibiotics were not effective, because of atypical lymphocytes in the peripheral blood and positive anti-human t-cell leukemia virus antibody, and he was transferred to our hospital. a chest radiograph and a ct scan revealed bilateral ground-glass opacities with huge multiple cysts. intensive treatment of pneumoc ... | 2001 | 11875817 |
| plasminogen-binding activity of enolase in the opportunistic pathogen pneumocystis carinii. | the glycolytic enzyme enolase is one of the most abundant proteins expressed in fungi and has been shown to be an immunodominant cell-wall-associated antigen of the pathogenic fungus, candida albicans. enolase has also been found on the surface of some mammalian cells where it functions as a plasminogen-binding motif and facilitator of plasminogen activation to plasmin. to investigate the immunogenicity of enolase in the opportunistic pathogen, pneumocystis carinii, the genomic and complementary ... | 2001 | 11798055 |
| pneumocystis carinii pneumonitis in haemophagocytic lymphohistiocytosis. | we report on a 10-y-old boy who developed pneumocystis carinii pneumonitis (pcp) as the dominant symptom at the onset of haemophagocytic lymphohistiocytosis (hlh). pcp is a common infection in patients with combined primary immunodeficiencies or acquired immunodeficiency syndrome but it has rarely been observed at the onset of hlh. typically, hlh presents as a febrile syndrome associated with cytopenia and hepatosplenomegaly. repeated bone marrow aspirates, spleen or lymph node biopsies are some ... | 2001 | 11853350 |
| [in vitro study of the anti-pneumocystis carinii effect of arteminsin derivatives]. | in vitro study was carried out to assess the effect of dihydroarteminsinin (dha) and sodium artesunate (ats) on pneumocystis carinii (pc). | 2001 | 11802960 |
| [pulmonary involvement due to disseminated non hodgkin lymphoma in one patient with aids]. | pulmonary involvement due to disseminated non hodgkin lymphoma (lnh), is an unusual cause of lung disease in aids patients. we report a 38 years old male patient, with advanced aids, who, in the course of three weeks, developed cough, dyspnea and fever. the chest x ray film showed diffuse thickening of the peribronchovascular connective tissue with possible mediastinal lymph node enlargement. the evolution was unfavorable with hypoxemia, severe anemia, liver damage and elevated levels of lactic ... | 2001 | 11836885 |
| induced sputum as a diagnostic specimen for pneumocystis carinii pneumonia in hiv positive patients. | 2001 | 11837488 | |
| cryptococcosis in patients from tikur anbessa hospital, addis ababa, ethiopia. | a study was done to investigate the occurrence of cryptococcus neoformans infection in patients admitted to tikur anbessa hospital. cryptococcus neoformans is an important opportunistic fungal pathogen in immunocompromised patients. the study was done over a period of 18 months, from october 1998 to april 2000. during this period, a total of 1088 cerebrospinal fluid (csf) specimens were sent to the bacteriology laboratory in tikur anbessa hospital, out of which 275 were subjected for india ink e ... | 2001 | 11921549 |
| pneumocystis carinii infection in red-bellied tamarins and cynomolgus monkeys, and the characterization of the mitochondrial large subunit ribosomal rna gene of pneumocystis carinii. | 2001 | 11906012 | |
| three new karyotype forms of pneumocystis carinii f. sp. carinii identified by contoured clamped homogeneous electrical field (chef) electrophoresis. | 2001 | 11906013 | |
| spatial analysis on the occurrence of pneumocystis carinii in the shrew notiosorex crawfordi in fragmented landscape in southern california. | 2001 | 11906015 | |
| parallel phylogenies of pneumocystis species and their mammalian hosts. | the single name pneumocystis carinii consists of an heterogeneous group of specific fungal organisms that colonize a very wide range of mammalian hosts. in the present study, mitochondrial large subunit (mtlsu) and small subunit (mtssu) rrna sequences of p. carinii organisms from 24 different mammalian species were compared. the mammals were included in six major groups: primates (12 species), rodents (5 species), carnivores (3 species), bats (1 species), lagomorphs (1 species), marsupials (1 sp ... | 2001 | 11906016 |
| cloning and sequence analysis of translational release factors erf1 and erf3 of pneumocystis carinii. | 2001 | 11906017 | |
| detailed structure of pneumocystis carinii chromosome ends. | 2001 | 11906018 | |
| typing of pneumocystis carinii f.sp. hominis isolates from nasopharyngeal aspirates of immunocompetent infants with bronchiolitis by dihydropteroate synthase gene analysis. | 2001 | 11906019 | |
| pneumocystis carinii detection using nested-pcr in nasopharyngeal aspirates of immunocompetent infants with bronchiolitis. | 2001 | 11906020 | |
| typing of pneumocystis carinii f.sp. hominis in patients with or without pneumocystosis. | 2001 | 11906021 | |
| stimulation of pneumocystis carinii encystment following necropsy. | 2001 | 11906024 | |
| a gene complex mediating cyst wall assembly and integrity in pneumocystis carinii. | 2001 | 11906025 | |
| synaptonemal complexes in the pre-cyst of pneumocystis carinii. | 2001 | 11906026 | |
| early acquisition of pneumocystis carinii in neonatal rats using targeted pcr and oral swabs. | 2001 | 11906027 | |
| pneumocystis carinii dihydropteroate synthase genotypes in hiv-infected persons residing in san francisco: possible implications for disease transmission. | 2001 | 11906028 | |
| putative transmissive form of pneumocystis carinii f. sp. carinii. | 2001 | 11906029 | |
| analysis of a pheromone receptor and map kinase suggest a sexual replicative cycle in pneumocystis carinii. | 2001 | 11906031 | |
| definitive structural identities of 42 sterol components in pneumocystis carinii. | 2001 | 11906032 | |
| pneumocystis carinii erg6 gene: sequencing and expression of recombinant sam:sterol methyltransferase in heterologous systems. | 2001 | 11906033 | |
| pneumocystis carinii its typing: doubtful evidence of genotype-related virulence. | 2001 | 11906034 | |
| pcr-rflp analysis of the dhps gene for the study of resistance of pneumocystis carinii to sulpha drugs in patients with co-infection pcp/hiv. | 2001 | 11906035 | |
| urokinase plasminogen activator and tgf-beta production in immunosuppressed patients with and without pneumocystis carinii. | 2001 | 11906036 | |
| recombinant cd40 ligand administration does not decrease intensity of pneumocystis carinii infection in scid mice. | x-linked hyper igm syndrome (him) is a rare congenital immunodeficiency recently demonstrated to be caused by a mutation in the gene encoding cd40 ligand. these patients are susceptible to pneumocystis carinii pneumonia, which implies an important role for cd40l in host defense against p. carinii. in this study we undertook to investigate whether treatment of p. carinii infected scid mice with murine recombinant cd40 ligand trimer (mucd40l) for 21 days would facilitate clearance of the organisms ... | 2001 | 11906038 |
| mechanisms of amino acid and glucose uptake by pneumocystis carinii. | 2001 | 11906039 | |
| pneumocystis carinii beta-glucan induces release of macrophage inflammatory protein-2 from primary rat alveolar epithelial cells via a receptor distinct from cd11b/cd18. | 2001 | 11906040 | |
| effect of the transcription factor gata-2 on phagocytic activity of alveolar macrophages from pneumocystis carinii-infected hosts. | 2001 | 11906041 | |
| changes in alveolar macrophage number are early events in pneumocystis carinii infection. | 2001 | 11906044 | |
| bronchoalveolar lavage fluid from pneumocystis carinii-infected rats inhibits phagocytosis in normal alveolar macrophages. | 2001 | 11906045 | |
| production and role of nitric oxide in the alveolar immune response to pneumocystis carinii. | 2001 | 11906046 | |
| pneumocystis carinii does not induce maturation of human dendritic cells. | 2001 | 11906047 | |
| pneumocystis carinii synthesizes four ubiquinone homologs: inhibition by atovaquone and bupravaquone but not by stigmatellin. | 2001 | 11906049 | |
| toward rational design of species-specific inhibitors of pneumocystis carinii thymidylate synthase and toxoplasma gondii dihydrofolate reductase-thymidylate synthase. | 2001 | 11906050 | |
| development of an rt-pcr on the heat shock protein 70 gene for viability detection of pneumocystis carinii f. sp. hominis in patients with pneumocystosis and in air sample. | to test the viability of pneumocystis carinii f. sp. hominis, an rt-pcr assay that employs specific primers from the heat shock protein 70 gene was developed. using this method, the viability of p.c. hominis in bronchoalveolar lavage fluids from patients developing pcp and in the environment of pcp patients was established. | 2001 | 11906051 |
| standardization of an in vitro drug screening assay by use of cryopreserved and characterized pneumocystis carinii populations. | 2001 | 11906052 | |
| pneumocystis carinii dihydropteroate synthase mutations and treatment with sulfa or sulfone regimens: a proposal for standardized definitions for clinical evaluation. | 2001 | 11906054 | |
| pneumocystis carinii pneumonia (pcp) in hiv-infected african children. | 2001 | 11887451 | |
| [opportunistic infections in hiv-positive patients hospitalized in the clinic of infectious diseases amg]. | opportunistic infections are one of the major problem among hiv infected patients still connected with high mortality. the aim of the investigation is to evaluate the incidence and mortality from opportunistic infections in hiv infected population in pomeranian region of poland. the paper presents analysis of incidence of opportunistic infections among 141 aids patients hospitalised in clinic for infectious diseases in gdańsk from 1988 to 2001/june/. in examined group 179 opportunistic infection ... | 2001 | 11984938 |
| [the essence of infection by opportunistic microorganisms]. | infection is regarded as an imbalance between microbial pathogenicity factors and the host defense systems. opportunistic infections are defined as infections rarely observed in humans with normal immune responses. the term immunocompromised (compromised) host refers to host in which one or more defence mechanisms are inactive and in which the probability of infection is therefore increased. hospital patients are often compromised host. compromised hosts exist even outside the hospital (smoking, ... | 2001 | 11984968 |
| antibiotic use in infants hospitalised with hiv-related pneumonia in harare, zimbabwe. | to describe the clinical features of infants admitted with hiv-related pneumonia and to describe antibiotic use in relation to recommended treatment guidelines. | 2001 | 12201021 |
| pneumocystis carinii f. sp. carinii synthesizes de novo four homologs of ubiquinone. | ubiquinone, coenzyme q, plays a pivotal role in electron transport and is a target for chemotherapy against a number of eukaryotic infectious agents, including pneumocystis carinii. coenzyme q10 was previously identified as the major ubiquinone homolog in p. carinii isolated and purified from rat lungs; coq9 was also present. in contrast, coq9 and coq8 (but not coq10) were detected in the lungs of uninfected rat controls. these observations suggested that the pathogen synthesizes coq10, and perh ... | 2001 | 12095106 |
| [adult t-cell leukemia/lymphoma. clinical aspects]. | background data: adult t-cell leukemia/lymphoma (atl) is a malignant proliferation of activated cd4+ t lymphocytes. the disease is almost exclusively found in patients living in retrovirus htlv-1 endemic areas. virology: in atl, monoclonal htlv-1 provirus is integrated into atypical lymphocytes, called clover-leaf lymphocytes. the pathogenic mechanism leading to htlv-1-induced leukemogenesis remains obscure. the disease generally occurs after a long latency period. four clinical subtypes: the di ... | 2001 | 12385062 |
| [pathological changes of diffuse pneumocystis carinii infection in the liver of an aids patient]. | to examine the pathological changes in the liver of an aids patient with complicated infection of pneumocystis carinii(pc). | 2001 | 12571974 |
| atovaquone suspension for treatment of pneumocystis carinii pneumonia in hiv-infected patients. | to describe clinical experience with atovaquone suspension for the treatment of pneumocystis carinii pneumonia (pcp) in hiv-infected patients. | 2001 | 11216929 |
| trimethoprim-sulfamethoxazole induced aseptic meningitis in a renal transplant patient. | a 45-year-old man underwent renal transplant for end-stage renal disease complicating systemic lupus erythematosis. within 24 hours of initiating pneumocystis carinii pneumonia (pcp) prophylaxis with trimethoprim-sulfamethoxazole (tmp-smx) he developed fever and confusion. cerebrospinal fluid examination revealed a pleocytosis but cultures were negative. the patient improved within three days after cessation of the tmp-smx but symptoms recurred rapidly upon drug rechallenge. drug-induced aseptic ... | 2001 | 11200873 |
| pneumocystis carinii pneumonia in patients without hiv infection. | pneumocystis carinii is an important, but sporadic, opportunistic pulmonary pathogen in immunosuppressed hiv seronegative persons. historically, patients at highest risk for p. carinii pneumonia are included infants with severe malnutrition, children with primary immunodeficiencies, patients with hematological malignancies, and recipients of solid organ or bone marrow transplants. recently, solid tumor patients, in particular those receiving high-dose corticosteroids for brain neoplasms, and pat ... | 2001 | 11202481 |
| the impact of cmv on the respiratory burst of macrophages in response to pneumocystis carinii. | infection of human monocyte-derived macrophages with cmv decreased the respiratory burst when cells were stimulated with opsonized zymosan or pneumocystis carinii (p. carinii). such an effect, though smaller, was also seen with heat-inactivated cmv, but only when triggered by zymosan. the effect was most pronounced in cells obtained from cmv antibody-negative donors. dexamethasone further reduced the respiratory burst, both in uninfected and cmv-infected cells. interferon-gamma increased the res ... | 2001 | 11207654 |
| pulmonary colonisation with pneumocystis carinii in an immunosuppressed hiv-negative patient: detection and typing of the fungus by pcr. | mostly pneumocystis carinii isolates from patients with acute pneumocystosis (pcp) have been typed until now. this report describes the typing of p. carinii organisms obtained from an hiv-negative patient without pcp. the patient underwent a broncho-alveolar lavage (bal) to investigate an abnormal chest x-ray. he was diagnosed with sarcoidosis. however, a low level of p. carinii organisms undetectable by microscopy was detected in bal fluid by two subsequent nested pcr assays: one assay amplifyi ... | 2001 | 11211229 |
| aetiology and outcome of pneumonia in human immunodeficiency virus-infected children hospitalized in south africa. | to determine the aetiology and outcome of pneumonia in human immunodeficiency virus (hiv)-infected children, we prospectively investigated 250 children hospitalized with pneumonia who were known or clinically suspected to be hiv-positive, or who required intensive care support in cape town, south africa. blood culture, induced sputum or bronchoalveolar lavage, nasopharyngeal aspirate and gastric lavage were performed. of the total, 151 children (60.4%) were hiv-infected. pneumocystis carinii pne ... | 2001 | 11236037 |