Publications

[palliation and correction of congenital cardiopathies during cardiac catheterization].		1980	2425828
a question of ethics?		1980	294280
[two-phase preparation of removable partial denture bases].		1980	283950
[law number 194 of 22 may 1978. regulations for social protection of maternity and on voluntary interruption of pregnancy. practical observations for complying with the law].	law 194 of the italian law code, promulgated on may 22, 1978, legalizes abortion on request if performed within the first trimester, and abortion for therapeutic reasons if performed after the first trimester. this law follows law 405 of july 29, 19 75, which promulgated the institution of family planning centers all over the country. unfortunately these centers, usually located inside a hospital, are not yet satisfactorily equipped to provide even for distribution of free contraception, let alo ...	1980	471307
advanced periodontal disease in young adults.		1980	273483
behavioral relapse prevention strategies in smoking cessation.	the study deals with the efficiency of various relapse prevention strategies in smoking cessation therapy. it is designed to examine the efficiency of cognitive and behavioral relapse prevention strategies in conjunction with transdermal nicotine substitution and booster sessions. the results show that application of the relapse prevention strategies in this study provided no significant increase in the long-term effectiveness of smoking cessation therapy. the abstinence rates of the five therap ...	1980	1601540
skull growth after partial prospective lower beak extirpation in chick embryos.	on one side of chick embryos in stage 28, part of the prospective lower beak or the entire prospective lower beak anterior to the buccal corner was removed surgically (clb-a and clb-b embryos, respectively). in another group the prospective lower beak was split in the midsagittal plane (cms embryos). the controls were shame-operated embryos (cs). the skulls of stage 39 clb-a and clb-b embryos showed changes in the lower beak as well as in the skull base, the pterygoid, the quadrate, the palatine ...	1980	434476
the senate finance committee and hospital cost containment.		1980	283850
neuropeptides of the silkworm, bombyx mori.	six neuropeptides of the silkworm, bombyx mori, have been isolated and chemically characterized during the past 10 years. they are bombyxin, prothoracicotropic hormone, pheromone-biosynthesis-activating neuropeptide/melanization-and-reddish-coloration hormone, diapause hormone, eclosion hormone, and adipokinetic hormone. recent progress in research on these neuropeptides is described.	1980	1601106
the ibr concept and plant sciences.		1980	550855
dental technicians' legislation passed in new south wales.		1980	283820
a modification to the blake gingivectomy knife.		1980	283811
the effects of hemifacial atrophy on dental growth.		1980	283809
polyploidy in gymnosperms.		1980	550825
federation dentaire internationale. fdi recommendations on mercury hygiene and radiation hygiene.		1980	283768
prevention of adult heart disease beginning in childhood: intervention programs.	multiple strategies are available to affect children's cardiovascular health. from clinic-based high-risk counseling to broad-based school or community programs, intervention strategies are being developed and tested to find the most effective means of changing the risk factors of youth to assure a healthier future for our children. since adoption of new behaviors is improved by consistent messages from multiple sources, a concerted effort is needed. the involvement of health professionals, educ ...	1980	2044108
reoperation for coronary artery bypass grafting.		1980	2044093
[health examination of diagnosis hyperlipidemia--clinical and clinical physiological findings].		1980	1271942
tolerance and physical dependence on drugs: introductory remarks.		1980	283729
biostatistical perspectives in the epidemiology of narcotic abuse.		1980	283724
[leukoencephalopathy in children with acute lymphocytic leukemia receiving preventive central nervous system therapy (author's transl)].		1980	273309
considerations of the cerebral response to painful stimulation: stimulus transduction versus perceptual event.		1980	283867
balancing service, research, and teaching in the hospital.		1980	283841
posted summaries of marital therapy.	summaries of marital therapy sessions, similar to those used in group psychotherapy by yalom, were posted to reach couples three or four days after each session. the summaries of 600 to 4,000 words included a narrative account of the session and some editorial comment by the therapist. couples completed a questionnaire assessing the use of the summaries. replies to questionnaires and clinical impressions indicate the summaries had good acceptability. couples felt the summaries increased their fo ...	1980	283798
product testing service.		1980	273630
the use of dental services in a population in northern norway.	the utilization of dental services was studied by means of records from dentist's files, a method which permits gathering of detailed information with high reliability and validity. 53% of the adult population of 358 persons living in a coastal community in northern norway had visited a dentist during a period of two years. in the group of 13% who were considered to be regular treatment attenders, number of teeth, sex and socio-economical status were the most influential predictors of utilizatio ...	1980	294118
effects of n-alkanols on the calcium current of intracellularly perfused neurons of helix aspersa.	the effects of n-alkanols on the calcium current (ica) were studied in molluscan neurons perfused intracellularly and voltage clamped using a suction pipette technique. all n-alkanols employed in this experiment (methanol, ethanol and butanol) decreased the peak amplitude of ica and caused acceleration of the decay of ica in a dose-dependent manner at all membrane potentials. the concentrations of n-alkanols required for these actions decreased as the hydrocarbon chain increased in length. the r ...	1980	2425895
development of haemophilus influenzae meningitis in patients treated with cefamandole.		1981	7229784
pathophysiologic basis for anemia associated with haemophilus influenzae meningitis: preliminary observations.		1981	7229795
treatment of purulent meningitis with a new cephalosporin-rocephin (ro 13-9904). clinical, bacteriological and pharmacological observations in 24 cases.	in 21 of the 24 cases the diagnosis of purulent meningitis was confirmed by culturing the causal agent and/or by immunological diagnosis. the daily dosage of rocephin ranged between 15 and 200 mg/kg administered in 2 i.m. injections. a cure was achieved in cases of meningococcal meningitis (1 case with sequelae: blindness in one eye), in 5 out of 6 cases of haemophilus influenzae meningitis (1 case with severe neuropsychiatric sequelae), in 3 out of 9 cases of pneumococcal meningitis and in 2 ou ...	1981	7249796
antibacterial properties of ro 13-99041, a long-acting new cephalosporin.	the antibacterial properties of the new cephalosporin ro 13-9904 were investigated in vitro and in vivo. the compound showed good activity against entero-bacteriaceae and gram-positive cocci, except streptococcus faecalis. haemophilus influenzae, neisseria gonorrhoeae and neisseria meningitidis were extremely susceptible to ro 13-9904. the bactericidal activity of ro 13-9004 was comparable to that of cefotaxime. the new cephalosporin showed better therapeutic efficacy in mice against pseudomonas ...	1981	7249797
treatment of severe lower respiratory tract infections with ceftriaxone (ro 13-9904). a pilot study.	two pilot comparative trials in 29 patients suffering from severe lower respiratory tract infections are described. 15 patients received 7-10.5 g ceftriaxone as a total dose and 14 received 28 g amoxicillin, both antibiotics being given by intravenous route during 1 week. the local and systemic tolerance of the drugs were satisfactory; no adverse reactions or relevant laboratory changes were noticed. the clinical response was favourable in all patients. the mot relevant pathogens found in the sp ...	1981	7249798
[clinical results of cefadroxil in pediatric field (author's transl)].	cefadroxil was administered at a daily dose of 50 mg/kg in 113 children including acute respiratory tract infections suspected to be a bacterial infection and other febrile diseases. among 41 cases in which pharyngeal culture was made twice before and after administration or urine and feces cultures were made, 20 cases (48.8%) were good bacteriologically, 5 cases (12.2%) were poor, and 16 cases (39.0%) were unknown. clinical efficacy was obtained in 105 cases (92.9%) out of 113 cases. microbial ...	1981	7253193
[some investigations on cefadroxil dry syrup (author's transl)].	mic of cefadroxil (cdx) against a group beta-streptococcus was distributed between 0.05-0.2 microgram/ml, that is, more susceptible than cephalexin (cex) an cefaclor (ccl), and susceptible to tetracycline (tc), erythromycin (em), lincomycin (lcm) resistant strains. serum level was higher than ccl administered orally at the same dose, and urinary excretion ratio after oral administration was good similarly to cex and ccl. patients treated were mostly scarlet fever and upper respiratory tract infe ...	1981	7253197
microbiology of chronic and recurrent otitis media with effusion in young infants.	chronic otitis media with effusion (ome) has been assumed to be sterile, since several reports in the literature have described unsuccessful attempts to culture bacteria from it. however, several recent studies have confirmed an earlier report that there is a significant frequency of bacteria in the middle ears of children with chronic and/or recurrent ome. similar studies in young infants with chronic and/or recurrent ome have not been previously reported. in this study, cultures were obtained ...	1981	7287316
[clinical evaluation of cefoxitin in children (author's transl)].	cefoxitin (cfx) was evaluated for its safety and efficacy in children. fifteen patients were treated with 73-125 mg/kg per day of cfx by intravenous administrations. the diagnosis of the patients were acute pharyngitis (4), pneumonia (2), pertussis and pneumonia (1), urinary tract infection (3); and the remaining 5 patients were esteemed to have nonbacterial infections. all the 10 patients of bacterial infections were cured after the cfx therapy. the pathogens recovered were streptococcus pyogen ...	1981	7289018
[laboratory and clinical studies on cefoxitin in pediatric field (author's transl)].	studies on antimicrobial activity, absorption and excretion and clinical use of cefoxitin in pediatric field were performed. 1. mic of cefoxitin was compared with that of cefazolin and/or ampicillin for clinical isolates of staphylococcus aureus (36 strains), escherichia coli (35 strains), klebsiella pneumoniae (34 strains) and haemophilus influenzae (80 strains). mic of cefoxitin against s. aureus was approximately 1-2 tubes higher than that of cefazolin. many strains of e. coli and k. pneumoni ...	1981	7289022
branhamella catarrhalis and other bacteria in the nasopharynx of children with longstanding cough.	nasopharyngeal cultures from 180 children aged 1 to 9 were examined. all children were suffering from cough for at least 10 days. the findings were compared to those from 67 non-coughing children. bordetella pertussis was isolated from 12.2% of the children in the study group but from none of the control children. branhamella catarrhalis was isolated from 66.1% of the children in the study group and from 28.3% in the control group (p less than 0.01). br. catarrhalis was more common in pure cultu ...	1981	7313564
the bacteriology of acute otitis media in children with special reference to streptococcus pneumoniae as studied by bacteriological and antigen detection methods.	the middle ear fluid (mef) was studied during an acute attack of otitis media in 519 children, aged 3 months to 6 years. streptococcus pneumoniae (pn) was cultured from 39% of the cases; serotypes 19, 6, 3 and 23 were the most common. haemophilus influenzae (hi) was cultured in 12%; only 2/64 strains were of type b. pn were found equally often in all age groups, but hi were significantly less often isolated in children older than 3 years. the number of negative cultures increased with the age of ...	1981	7313573
[fulminant pneumococcal septicemia in splenectomized patients].	four cases of fulminant pneumococcal septicemia in splenectomized patients are reported. three had undergone splenectomy for trauma 42, 28 and 14 years prior to the septicemia. the fourth had been splenectomized for suspected lymphoma 3 years earlier. in 3 out of 4 patients the symptomatology was so rapidly progressive that a physician was consulted within 12 hours. two patients hospitalized after a second consultation and 20 hours after the first symptoms had evidence of septic shock, dissemina ...	1981	7313655
causes of pneumonia presenting to a district general hospital.	the incidence of bacterial, viral, mycoplasma, and rickettsial infections has been assessed prospectively in 210 adult patients with pneumonia who presented to a district hospital over a six-year period. one hundred and thirteen infective agents were detected in 103 patients. the agent most frequently detected was mycoplasma pneumoniae which accounted for 30 infections. a bacterial pathogen was found in 43 patients. streptococcus pneumoniae was the most common of these (24 patients); staphylococ ...	1981	7314031
[clinical studies on cefroxadine in the field of pediatrics (author's transl)].	cefroxadine dry syrup was administered to 57 children with acute febrile respiratory tract infections and 2 children with scarlet fever in the dose of 40 mg/kg/day q.i.d. for 2 approximately 7 days. 65 strains of organism were isolated as pathogen from the 59 patients, and 50 of the 65 strains (76.9%) showed bacteriologically good responses. clinically, 55 children (93.2%) had good response. out of 63 strains isolated from the 57 cases with respiratory infections, 48 strains (76.2%) showed good ...	1981	7334585
bacampicillin twice daily: a dose-response study in acute exacerbations of chronic bronchitis.	the purpose of the study was to select the minimum effective dose of bacampicillin in a systematic dose-response study in hospitalised patients with acute exacerbations of chronic bronchitis. in all 37 patients haemophilus influenzae or h. parainfluenzae was isolated from purulent sputum before treatment with 400, 800 or 1200 mg of bacampicillin twice daily for 10 days. there was a significant relationship between the administered dose and clinical results at the end of treatment (p less than 0. ...	1981	7347694
antibiotic treatment of haemophilus influenzae type b meningitis: the problem of bacterial resistance.		1981	6912164
meningitis caused by acinetobacter calcoaceticus var anitratus. a specific hazard in neurosurgical patients.	acinetobacter calcoaceticus var anitratus caused meningitis in five patients between 1968 and 1978 at two hospitals affiliated with boston university school of medicine. all patients had had head trauma or neurosurgical procedures prior to the development of meningitis. the course of the disease was relatively indolent in that fulminant disease did not occur even when initial therapy was inappropriate and bacteria persisted in csf. all five patients survived. on gram's stain of csf, a calcoaceti ...	1981	7469844
fever in haemophilus influenzae type b meningitis.	ninety-nine cases of haemophilus influenzae type b (hib) meningitis were analyzed to assess the causes of secondary and persistent fever and outcome of treatment. secondary fever developed in 47 patients, 11 had persistent fever and 4 patients died. secondary fevers were associated with intercurrent illness in 30 per cent, drug fever in 15 per cent, and neurologic complications in 13 per cent. serious neurologic or other complications were no more common in patients with than in those without se ...	1981	7471596
cefamandole bone diffusion in patients undergoing total hip replacement.	cefamandole penetration was studied in 32 normal bone specimens. no antibiotic bone binding was found. blood contamination of bone samples was measured by the haemoglobin method. mean corrected levels attained (5.8 micrograms/g) exceed mic values of sensitive staphylococcus aureus, haemophilus influenzae and enterobacteriaceae. similar diffusion was observed in cortical and trabecular bone. the results obtained invite further studies on preoperative prophylaxis and treatment of osteomyelitis.	1981	7226972
lumbar puncture-induced meningitis.	a retrospective study was done to evaluate the risk of lumbar puncture-induced meningitis. fourteen percent (23/165) of patients with bacteremia caused by streptococcus pneumoniae, haemophilus influenzae, neisseria meningitis, and groups a and b streptococci had spontaneous meningitis (without a preceding lumbar puncture). in contrast, only 0.8% (7/924) of patients with blood culture containing other organisms had spontaneous meningitis and 2.1% (3/140) of these patients had clinical courses con ...	1981	7206149
meningitis in the central arctic: a 4-year experience.	there were 37 cases of meningitis during a 4-year period among the native and white populations served by the churchill health centre in northern manitoba, an annual incidence of 128 per 100 000 in the overall population and of 202 per 100 000 among the inuit. bacterial meningitis predominated; neisseria meningitidis and haemophilus influenzae each accounted for one third of the cases. there were five deaths, and 14 of the survivors had severe sequelae. therefore, although the doctors and nurses ...	1981	7214288
a polysaccharide-protein complex from haemophilus influenzae type b. iii. vaccine trial in human adults.	polysaccharide-protein complex prepared from haemophilus influenzae type b strain eagan was evaluated for toxicity and immunogenicity in adult volunteers given intramuscular injection. most subjects had moderate local inflammation that was maximal the day after vaccination. no lot of vaccine significantly exceeded a saline placebo in production of systemic symptoms. neither the local nor the systemic reactions of individual subjects appeared to be related to prevaccination serum antibody titers. ...	1981	7035578
new method that uses binding of immunoglobulin a to group a streptococcal immunoglobulin a fc receptors for demonstration of microbial immunoglobulin a protease activity.	a new method is described for the detection of bacterial immunoglobulin a (iga) protease which splits iga into fab and fc fragments. the method takes advantage of a recent finding that receptors for iga fragments occur commonly among type 4 group a streptococci. the bacterial preparation to be tested for protease activity was first incubated with radiolabeled purified iga1 myeloma protein, and the proportion of radioactivity bound to a standard suspension of the streptococci was then measured. s ...	1981	7016917
ceforanide and cefazolin therapy of pneumonia: comparative clinical trial.	ceforanide is a new (parenteral) long-acting cephalosporin with antimicrobial activity comparable to those of other second-generation cephalosporins. in a randomized prospective study, patients with community-acquired bacterial pneumonia were treated with ceforanide at 0.5 g every 12 h (28 cases) or with cefazolin at 1.0 g every 8 h (26 cases). the study groups were comparable in clinical and laboratory findings, including etiological diagnosis. streptococcus pneumoniae was isolated from the spu ...	1981	7034641
[quantitative bacterial ecology of normal nasal mucosa].	a quantitative research into the aerobic bacteria of human nasal cavities has been carried out; 183 healthy individuals observed, negative results 18 (9.83%). streptococcus, enterococcus, staphylococcus aureus, staphylococcus epidermidis, micrococcus, streptococcus pneumoniae, neisseria, were numerically determined and the incidence of each single species or genus exactly specified. among gram-negative bacteria, enterobacter, providencia, proteus, citrobacter freundii, haemophilus influenzae, kl ...	1981	7034653
[comparison of 2 bacteriological methods. sputum examination associated with the immunoelectrophoretic analysis of the blood serum in the detection of haemophilus influenzae infection in chronic bronchitis].		1981	7036101
comparison of the quantitative direct plating method and the bactec procedure for rapid diagnosis of haemophilus influenzae bacteremia in children.	the efficacy and reproducibility of the quantitative direct plating (qdp) method and the semi-automated bactec radiometric system (bbl microbiology systems, cockeysville, md.) were analyzed for the rapid diagnosis of haemophilus influenzae bacteremia on the basis of 41 positive cultures from 35 patients. the qdp method detected 61% and bactec only 19% of the positive cultures within the first 12 h. similarly, the qdp procedure yielded growth of h. influenzae in 56% of the cultures before a posit ...	1981	7037836
lethal meningoencephalitis and septicemia caused by haemophilus influenzae type f in an adult with multiple myeloma.	a patient with chemotherapy-treated multiple myeloma developed overwhelming sepsis and meningoencephalitis with haemophilus influenzae type f. typable h. influenzae other than type b has only rarely been reported as a cause of serious disease in adults. the patient's immunosuppressed status presumably predisposed her to this unusual infection.	1981	7037842
[protracted pneumonia and its etiology].		1981	7027504
a combination of amoxicillin and clavulanic acid in the treatment of respiratory tract infections caused by amoxicillin-resistant haemophilus influenzae.	this study was undertaken to evaluate the efficacy of a fixed combination of amoxicillin and clavulanic acid in 33 patients with chronic or recurrent respiratory tract infections (r.t.i.), mainly bronchitis. in two patients bronchopneumonia was diagnosed, and in one cystic fibrosis. the patients were treated with 750 mg of the drug combination (500 mg amoxicillin/250 mg clavulanic acid) t. i. d. for seven or ten days. good clinical success was obtained in 17 patients and a clear improvement in a ...	1981	7028635
[biochemical characterization of haemophilus-strains by using the api 20 e- and api 50e-testsystem (author's transl)].	the commercially available test systems api 20e and api 50e were used to characterize 74 reference strains and clinical isolates of haemophilus influenzae, h. aegyptius, h. parainfluenza, h. paraphrophilus and h. paraphrohaemolyticus the strains were grown on chocolate agar followed by suspending some colonies colonies in proteose pepton medium, ph 7.6, supplemented with the x- and v-factors. the alkaline suspension was used to inoculate the cups of the test kits. the alkali of the medium did no ...	1981	7029968
antagonism of ampicillin and chloramphenicol for meningeal isolates of group b streptococci.	the increasing prevalence of ampicillin-resistant haemophilus influenzae type b has led to the recommendation that ampicillin and chloramphenicol be given as the initial therapy for suspected bacterial meningitis in infants and children. however, during the first 2 months of life, h. influenzae type b is a rare cause of meningitis, whereas group b streptococcus is the most frequently isolated agent. since ampicillin and chloramphenicol have been shown to be antagonistic for other streptococci, a ...	1981	7030197
biochemical characterization of haemophilus species with the minitek differentiation system.	characterization of 102 haemophilus strains by the minitek differentiation system (bbl microbiology systems, cockeysville, md.) was compared with that by the conventional method. the results obtained by the two methods were in good agreement (p less than 0.001; test of independence). therefore, this system was found to be applicable for the identification of haemophilus species in routine clinical bacteriology.	1981	7031090
antigen of haemophilus influenzae in bronchial tissue.	haemophilus influenzae antigen was detected in five of seven bronchial biopsies obtained from patients undergoing diagnostic bronchoscopy. antibody against h influenzae antigens was obtained from a patient with bronchiectasis. immunofluorescent techniques were used. this provides further evidence to support the pathogenicity of h influenzae in lower respiratory tract disorders.	1981	7031978
detection of beta-lactamase in haemophilus influenzae by immunofluorescence.	beta-lactamase immunizing antigen was prepared from cells of an ampicillin-resistant strain of haemophilus influenzae by cold osmotic shock followed by deae column fractionation. nonspecific antibodies were removed by cross-absorption with cells of an ampicillin-sensitive strain of h. influenzae. an residual nonspecific antibodies remaining after cross-absorption were effectively eliminated by dilution of the anti-beta-lactamase serum 1:50. twenty strains were tested for presence of beta-lactama ...	1981	7032677
hemophilus influenzae infections: part ii.		1981	7032843
molecular size characterization of bacterial capsular polysaccharide vaccines with sepharose cl-2b.		1981	7033224
cellulitis: initial management.	although staphylococcus aureus and streptococcus pyogenes cause the majority of cellulitis, recent studies have shown a significant role for hemophilus influenzae in facial, and less frequently, nonfacial infections. we devised an algorithm for the initial management of cellulitis based on our previous investigations showing a correlation of this organism with fever, leukocytosis, and facial involvement. children were divided into four groups characterized as follows: group i - extremity, temper ...	1981	7018329
interaction of haemocin with escherichia coli.	the bactericidal activity of haemocin, a bacteriocin produced by haemophilus influenzae b, for escherichia coli cr34 could be blocked by the addition of 2,4-dinitrophenol. no inhibition by 2,4-dinitrophenol of the haemocin activity on h. influenzae rd strain c25 was demonstrated. the data suggest an energy-dependent step in the mode of action of haemocin on strain cr34.	1981	7018393
diffusion of ceftriaxone (ro 13-9004/001) in the cerebrospinal fluid. comparison with other beta-lactam antibiotics in dogs with healthy meninges and in dogs with experimental meningitis.	after i.v injection of 50 and 100 mg/kg ceftriaxone in 1 h in dogs with healthy meninges, the cerebrospinal fluid (csf) concentrations found between minutes 90 and 240 were an average of 0.37 (0.32-0.41) and 1.22 microgram/ml (1.02-1.56), respectively. in dogs with meningitis a dosage of 50 mg/kg yielded high concentrations from minutes 60 to 240: on average, 13.0 microgram/ml (9.9-14.9); 9.9 microgram/ml in the fourth hour. the concentrations obtained in dogs with healthy meninges were 10-100 t ...	1981	7018851
quantitation of antibodies to haemophilus influenzae type b in humans by enzyme-linked immunosorbent assay.	the enzyme-linked immunosorbent assay was adapted to detect serum immunoglobulin g, immunoglobulin m, immunoglobulin a, and secretory immunoglobulin a antibodies to haemophilus influenzae type b capsular polysaccharide in humans. i studied serum samples from 92 healthy children of various ages, 50 healthy adults, 24 patients with various h. influenzae type b infections, and 16 patients with clinical signs of epiglottis and cellulitis suspected to be caused by h. influenzae type b. the mean antib ...	1981	7019237
detection of bacterial pathogens in purulent clinical specimens by immunofluorescence techniques.	a technique is described which may be used to identify haemophilus influenzae type b, streptococcus pneumoniae, group a and b streptococci, and staphylococcus aureus in smears of clinical specimens.	1981	7019240
[role of haemophilus influenzae in the development of nonspecific lung diseases].		1981	7020152
a comparison of conventional and minitek systems for biotyping haemophilus influenzae.	two hundred pediatric isolates of haemophilus influenzae from various sources were biotyped using the media described by kilian in parallel with the minitek system. there was an excellent correlation (97.7%) between the two systems. ninety-five per cent of blood and cerebrospinal fluid (csf) isolates were biotype i. biotypes ii and iii were most frequent among isolates from sources other than blood and csf. production of beta-lactamase was limited to biotype ii in the blood and csf isolates, but ...	1981	7020401
florida and the spanish flu.		1981	7021757
the effects of influenza on host defenses.		1981	7024434
transferable multiple antibiotic resistance in haemophilus influenzae.		1981	7026525
minimum number of bacteria needed for antigen detection by counterimmunoelectrophoresis: in vivo and in vitro studies.	threshold concentrations of streptococcus pneumoniae type 3, haemophilus influenzae type b, and streptococcus sp. group b type ib required for positive counterimmunoelectrophoresis reactions were determined in vivo and in vitro. animals were infected intraperitoneally with various concentrations of microorganisms: adult mice with s. pneumoniae, suckling rats with h. influenzae, and 3-week-old mice with streptococcus sp. group b. at 24 h after infection a minimum blood concentration of 10(3) colo ...	1981	7014618
investigation of enzyme immunoassay time courses: development of rapid assay systems.	an enzyme immunoassay (eia) consists of a series of antigen-antibody reactions which result in the binding of an enzyme-labeled antibody to a solid phase. the performance time of an eia determination is thus largely dependent upon the time required for the antigen-antibody reactions. in an attempt to develop a rapid eia system, we investigated the time course of an eia system for the measurement of haemophilus influenzae type b polysaccharide. we found that, although the use of short incubations ...	1981	7014623
[haemophilus influenzae meningitis--new diagnostic possibilities].		1981	7014991
[repartition of haemophilus influenzae biotypes responsible of purulent meningitis. (study of 50 strains) (author's transl)].	the repartition of the haemophilus influenzae biotypes responsible of meningitis in world were reviewed. in senegal the vast majority of strains of haemophilus influenzae isolated from csf belonged to biotype i (94%), the biotypes ii and iv were rarely encountered (respectively 4% and 2%). the biotypes of repartition in africa is similar to this encountered in other world areas.	1981	7015250
cellulitis: treatment with cefoxitin compared with multiple antibiotic therapy.	cefoxitin, a parenteral cephamycin beta-lactam antibiotic was prospectively evaluated as a single drug alternative in 31 children with cellulitis and the results of therapy were compared retrospectively with those from prevailing multiple antibiotic therapy for cellulitis in 56 children. periorbital and lower extremity cellulitis accounted for more than 60% of the cases in both study groups. the most common bacterial agents included haemophilus influenzae, staphylococcus aureus, and group a beta ...	1981	7015265
ampicillin-resistant haemophilus influenzae and otitis media.		1981	7015826
evaluation of cefaclor.	the chemistry, pharmacology, pharmacokinetics, bacterial spectrum, clinical use, dosage, adverse reactions, and dosage forms and cost of cefaclor are reviewed. cefaclor, a congener of cephalexin monohydrate, is a new semisynthetic cephalosporin antibiotic. it is well absorbed when given orally on an empty stomach; absorption is delayed by the presence of food. although metabolism may play a role in the disposition of cefaclor, elimination is primarily renal. cefaclor's spectrum of activity is si ...	1981	7011003
controlled comparative trial of bacampicillin and amoxicillin in therapy of bacterial infections of the lower respiratory tract.	in this study the efficacy of bacampicillin and amoxicillin in treatment of bacterial lower respiratory tract infection were compared. thirty-eight patients were treated with bacampicillin (800 mg twice a day), and 39 were treated with amoxicillin (500 mg three times a day). conditions treated included pneumonia, exacerbation of chronic bronchitis, and bronchiectasis. the two groups were roughly comparable in terms of demographic factors and clinical diagnosis. the most common pathogens were str ...	1981	7012996
haemophilus influenzae type b capsular polysaccharide detection and measurement by an enzyme-linked immunosorbent assay (elisa).	a direct sandwich enzyme-linked immunosorbent assay (elisa) was developed to detect haemophilus influenzae type b capsular antigen. using polystyrene as the solid phase and peroxidase-labelled rabbit antibody the assay detected the antigen in concentrations of 0.1 ng/ml. linearity was achieved within the range of 1ng to 10 microgram/ml. subtle measurements of haemophilus influenzae type b capsular antigen in body fluids are possible through elisa which is superior to counterimmunoelectrophoresis ...	1981	7013364
rifampin chemoprophylaxis for household contacts of patients with invasive infections due to haemophilus influenzae type b.	to determine the efficacy of rifampin chemoprophylaxis in eradication of oropharyngeal carriage of haemophilus influenzae type b, we conducted a multicenter, double-blind, placebo-controlled trial among household contacts of patients hospitalized for invasive hib infection. seventy-nine index patients and 400 close contacts were studied; 26.5% of contacts were colonized. the efficacy of rifampin (10 mg/kg/dose, 600 mg/dose maximum, twice daily for two days) in eradicating carriage was 52% and va ...	1981	7009819
mutation induction in haemophilus influenzae by icr-191. i. development of a detection system for frameshift mutations.	the investigation of mutagenic mechanisms in haemophilus influenzae has been confined until now to mutagens that normally produce mainly base pair substitutions. this paper describes the development of a system suitable for detecting frameshift mutations induced by icr-191. the system involves reversions from thymidine dependence to thymidine independence. evidence is presented from a comparison of the responses to icr-191 and to n-methyl-n'-nitro-n-nitrosoguanidine that the system is specific f ...	1981	7010138
iodometric spot test for detection of beta-lactamase in haemophilus influenzae.	a simple iodometric spot test for detecting beta-lactamase activity in haemophilus influenzae was compared with the capillary procedure for detecting beta-lactamase and the bauer-kirby disk susceptibility procedure. isolates were classified similarly by all three procedures.	1981	7007425
bacterial meningitis in children in barbados.		1981	6979832
[trend of sensitivity of h. influenzae to ampicillins during 1973-1981 (author's transl)].		1981	6980426
[composition of transforming dna of haemophilus influenzae irradiated with near-ultraviolet light].		1981	6980437
the pathophysiology of influenzal pneumonia in 1918.		1981	7038618
hemophilus influenzae type b soft tissue infections of the head and neck.	hemophilus influenzae soft tissue infections produce a variety of specific and dangerous pathologic manifestations in the head and neck. problems include periorbital cellulitis and abscess, sinusitis, supraglottitis and otitis media. complications include meningitis, airway obstruction and death. pediatric patients are especially susceptible to these infections and complications. effective management includes correct diagnosis, prevention of complications, and high doses of appropriate antibioti ...	1981	7005582
nasal carriage of pathogenic bacteria in kalauna village, goodenough island.	nasal swabs from 62 villagers of kalauna, goodenough island were cultured. streptococcus pneumoniae was isolated from 16 of 25 adults (64%) and 36 of 37 children (97%). significant regional clustering of prevalent pneumococcal serotypes were seen among families in core hamlets. five of 20 adults (20%) and 30 of 37 children (81%) grew haemophilus influenzae all of which were biotypable. a variety of faecal gram negative bacilli comprising enterobacteria, alcaligenes species and an aeromonad were ...	1981	6978581
otitis media in the highlands of papua new guinea.		1981	6978582
antimicrobial susceptibility of haemophilus influenzae isolates in wellington hospital.	103 strains of haemophilus influenzae isolated during june to october 1980 were tested for susceptibility to seven antimicrobials using the dynatech mic 2000 system. six strains (5.8 percent) were resistant to ampicillin (one type b, five untypable) and all of these produced beta-lactamase. two of these six strains were isolated from blood; one untypable strain in an adult with pneumonia, and one type b strain in a child with acute epiglottitis. no resistance to the other six antimicrobials was ...	1981	6977748
[vaccination against bacterial meningitis (author's transl)].		1981	6979409
haemophilus influenza sepsis and shock secondary to biliary infection in an adult.	a 46-year-old woman was seen with biliary obstruction secondary to a pancreatic tumor. after undergoing a percutaneous liver biopsy, she became septic and went into shock. haemophilus influenzae type be bacteremia and biliary infection were verified. with treatment, the patient recovered from the infection. biliary infection by h influenzae is rare, and fulminant infections in adults are even more uncommon. hazards of invasive diagnostic procedures in patients with obstructive jaundice are discu ...	1981	6972200
persistent purulent otitis media.	of 429 children with acute otitis media who returned for follow-up evaluation, 49 (11%) were unresponsive to a 10- to 14-day course of ampicillin, amoxicillin, or erythromycin/sulfisoxazole. patients with persistent purulent otitis media were noted to have immobile, bulging, yellow or grey, abscessed tympanic membranes at the follow-up visit. a myringotomy was performed on 45 children. cultures of middle-ear exudate yielded ampicillin-resistant haemophilus influenzae in 14 (31%), ampicillin-susc ...	1981	6972278
experimental meningitis produced by haemophilus influenzae type 'b' in infant rats.		1981	6972350
structural studies of the capsular polysaccharide elaborated by haemophilus influenza type d.	the structure of the capsular polysaccharide elaborated by haemophilus influenzae type d has been investigated, methylation analysis and n.m.r. spectrometry being the principal methods used. it is concluded that the polysaccharide is composed of repeating units having the structure: leads to 4)-beta-d-glcpnac-(1 leads to 3)-beta-d-manpnaca-(1 leads to. in addition, single residues of l-alanine, l-serine, or l-threonine, in the proportions 2:2:1, are linked, through their amino groups, to c-6 of ...	1981	6976205