Publications

molecular epidemiology of a shigella flexneri outbreak in a mountainous township in taiwan, republic of china.	an outbreak of shigellosis occurred in a township of nantou conuty in central taiwan from august to october in 1996. the infections extended to two neighboring townships and continued to the end of 1996. forty cases were confirmed during the period, in contrast to only one confirmed case in nantou county in 1996 before the outbreak. all of these 41 cases in 1996 were identified as infections with shigella flexneri serotype 2a. in order to trace the source of the infections, the 41 isolates recov ...	2001	11230426
increased nitrite and nitrate concentrations in sera and urine of patients with cholera or shigellosis.	nitric oxide (no) is an important regulator of cell function. in the intestine, no regulates blood flow, peristalsis, secretion, and is associated with inflammation and tissue injury. the objectives of this study were to assess and compare the role of no in cholera, a noninflammatory enteric infection, and in shigellosis, a bacterial inflammation of the colon.	2001	11232692
periplasmic transit and disulfide bond formation of the autotransported shigella protein icsa.	the shigella outer membrane protein icsa belongs to the family of type v secreted (autotransported) virulence factors. members of this family mediate their own translocation across the bacterial outer membrane: the carboxy-terminal beta domain forms a beta barrel channel in the outer membrane through which the amino-terminal alpha domain passes. icsa, which is localized at one pole of the bacterium, mediates actin assembly by shigella, which is essential for bacterial intracellular movement and ...	2001	11208794
controlled expression in klebsiella pneumoniae and shigella flexneri using a bacteriophage p1-derived c1-regulated promoter system.	the utility of promoters regulated by the bacteriophage p1 temperature-sensitive c1 repressor was examined in shigella flexneri and klebsiella pneumoniae. promoters carrying c1 operator sites driving lacz expression had induction/repression ratios of up to 240-fold in s. flexneri and up to 50-fold in k. pneumoniae. the promoters exhibited remarkably low basal expression, demonstrated modulation by temperature, and showed rapid induction. this system will provide a new opportunity for controlled ...	2001	11698385
validation of salmonellosis and shigellosis diagnostic test kits at a provincial hospital in thailand.	rapid diagnosis of salmonellosis and shigellosis was performed using six different diagnostic test kits which recently have been made available commercially. they were salmo-dot, typhi-dot, shigel dot a, b, c, and d test kits for detection of salmonella spp., group d salmonellae, and groups a, b, c, and d shigella spp., respectively. the principle of all test kits is a membrane (dot) elisa using specific monoclonal antibodies to the respective pathogens as the detection reagents. the present stu ...	2001	11699718
shigella sonnei outbreak among men who have sex with men--san francisco, california, 2000-2001.	shigella sonnei causes approximately 10,000 cases of gastroenteritis each year in the united states. these infections occur predominately among young children and usually are associated with poor hygienic conditions in child-care settings. outbreaks of shigellosis among men who have sex with men (msm) have occurred because of direct or indirect oral-anal contact but usually are caused by shigella flexneri. this report describes an investigation of s. sonnei cases that occurred among msm in san f ...	2001	11699845
ipac from shigella and sipc from salmonella possess similar biochemical properties but are functionally distinct.	invasion plasmid antigen c (ipac) is secreted via the type iii secretion system (ttss) of shigella flexneri and serves as an essential effector molecule for epithelial cell invasion. the only homologue of ipac identified thus far is salmonella invasion protein c (sipc/sspc), which is essential for enterocyte invasion by salmonella typhimurium. to explore the biochemical and functional relatedness of ipac and sipc, recombinant derivatives of both proteins were purified so that their in vitro bioc ...	2001	11703668
pathoadaptive mutations that enhance virulence: genetic organization of the cada regions of shigella spp.	pathoadaptive mutations improve the fitness of pathogenic species by modification of traits that interfere with factors (virulence and ancestral) required for survival in host tissues. a demonstrated pathoadaptive mutation is the loss of lysine decarboxylase (ldc) expression in shigella species that have evolved from ldc-expressing escherichia coli. previous studies demonstrated that the product of ldc activity, cadaverine, blocks the action of shigella enterotoxins and that the gene encoding ld ...	2001	11705922
mxim and mxij, base elements of the mxi-spa type iii secretion system of shigella, interact with and stabilize the mxid secretin in the cell envelope.	the type iii secretion pathway is broadly distributed across many parasitic bacterial genera and serves as a mechanism for delivering effector proteins to eukaryotic cell surface and cytosolic targets. while the effectors, as well as the host responses elicited, differ among type iii systems, they all utilize a conserved set of 9 to 11 proteins that together form a bacterial envelope-associated secretory organelle or needle complex. the general structure of the needle complex consists of a trans ...	2001	11717255
lifestyles of the intracellular.		2001	11728864
characterization of the interaction partners of secreted proteins and chaperones of shigella flexneri.	the type iii secretion (tts) system of gram-negative pathogenic bacteria is composed of proteins that assemble into the tts machinery, proteins that are secreted by this machinery and specific chaperones that are required for storage and sometimes secretion of these proteins. many sequential protein interactions are involved in the tts pathway to deliver effector proteins to host cells. we used the yeast two-hybrid system to investigate the interaction partners of the shigella flexneri effectors ...	2001	11737652
blockade of cd14 aggravates experimental shigellosis.	shigella infections lead to severe inflammation associated with destruction of colonic mucosa. we assessed the effect of in vivo blockade of cd14 on the outcome of experimental shigella infection in rabbits. a total of 17 rabbits were divided into two groups: 8 received a single i.v. dose of anti-rabbit cd14 monoclonal antibody prior to infection with an invasive shigella flexneri strain; the remainder served as controls. the anti-cd14-treated rabbits exhibited more severe tissue destruction and ...	2001	11753214
epidemiology of shigellosis in lagos, nigeria: trends in antimicrobial resistance.	antimicrobial susceptibility of shigella spp. and escherichia coli, isolated from diarrhoeal patients in lagos, was studied from march 1999 to february 2000. four hundred fifty-nine isolates were identified as shigellae (62) and e. coli (397). shigella flexneri, s. dysenteriae, s. boydii, and s. sonnei accounted, respectively, for 51.6%, 17.7%, 17.7%, and 13% of the total number of shigellae isolated. eleven cases of shigellosis occurred in the age group of 0-9 years, 22 cases in the age group o ...	2001	11761772
evaluation of culture media for enrichment and isolation of shigella sonnei and s. flexneri.	the performance of gram-negative (gn) broth with (10 microg/ml) and without novobiocin, shigella broth (sb) with 0.5 and 3.0 microg/ml novobiocin, all incubated at 37 degrees c (sb with 3.0 microg/ml novobiocin also at 42 degrees c) and buffered brilliant green bile glucose (ee) broth with 1.0 microg/ml novobiocin incubated at 37 and 42 degrees c were evaluated for resuscitation and growth of shigella sonnei and s. flexneri (eight strains; unstressed, chill-stressed and acid-stressed) and non-sh ...	2001	11764191
protective role of human lactoferrin against invasion of shigella flexneri m90t.	lactoferrin is an iron-binding protein found in human mucosal secretions such as milk. a variety of functions have been ascribed to this protein, it appears to contribute to antimicrobial host defense. still its overall physiological role remains to be defined. we sought to study the role of recombinant human lactoferrin (rhlf) in shigella infection. invasion of epithelial cells is essential to the development of bacillary dysentery. shigella flexneri 5 m90t, a virulent strain, was evaluated in ...	2001	11787716
neonatal shigellosis.		2001	11794928
[isolation of provisional serovars of shigella in diarrheal cases of tourists].	twenty-four shigella strains of provisional serovars were isolated from travellers with diarrhea during 1993-2000 at osaka airport- and kansai airport-quarantine station. the outline of these cases were as follows. 1) the provisional serovars of these strains (number of cases) were s. dysenteriae 93-119 (2), s. dysenteriae 204/96 (4), s. dysenteriae i9809-73 (4), s. flexneri 88-893 (9), and s. boydii e16553 (5). 2) symptoms of these cases were diarrhea, abdominal pain, fever, and vomiting. the r ...	2001	11806136
shigella septicaemia in adults: report of two cases and mini-review.	we report 2 cases of shigella septicaemia in adult patients.	2001	11817302
[investigation of a shigellosis outbreak in a rural zone of senegal].	the investigation of this outbreak took place in niakhar (ird project study area), a rural area located 150 km east of dakar. covering 30 villages, with a population of about 30,000 inhabitants, the area has been under demographic and epidemiological surveillance. in 1999, the surveillance allowed 973 cases of shigellosis to be recorded out of 1,751 cases of dysenteric diarrhoeas. the outbreak reached a peak during the raining season (73% of the cases in september and october). all the villages ...	2001	11861195
synthesis and antimicrobial activity of some 1,2,4-triazole-3-mercaptoacetic acid derivatives.	ethyl 5-(2-furyl)-4-ethyl-1,2,4-triazole-3-mercaptoacetate (2), 5-(2-furyl)-4-ethyl-1,2,4-triazole-3-mercaptoacetic acid hydrazide (3) and a series of new n-alkylidene/arylidene-5-(2-furyl)-4-ethyl-1,2,4-triazole-3-mercaptoacetic acid hydrazides (4a-f) were synthesized and evaluated for in vitro antibacterial activity against staphylococcus aureus atcc 6538. staphylococcus epidermidis atcc 12228, klebsiella pneumoniae atcc 4352, pseudomonas aeruginosa atcc 1539, escherichia coli atcc 8739, shige ...	2001	11829115
synthesis and evaluation of antibacterial activity of some 2-[[alpha-(4-substituted benzoyloxy)-alpha-phenylacetyl or methylacetyl]amino]-5-(4-methoxyphenyl)- 1,3,4-oxadiazoles.	in this study, a new series of 1-[[alpha-(4-substitutedbenzoyloxy)-alpha-phenylacetyl or methylacetyl]amino]-5-(4-methoxyphenyl)-1,3,4-oxadiazoles were obtained by condensation of 2-[(alpha-chloro-alpha-phenylacetyl or alpha-bromopropionyl)amino]-5-(4-methoxyphenyl)1,3,4-oxadiazoles with sodium salts of 4-substituted benzoic acids. structures of the compounds were assigned on the basis of spectral data (uv, ir, 1h nmr, el ms) and elemental analyses. the antibacterial activities of the novel comp ...	2001	11829119
survivability of shigella dysenteriae type 1 & s. flexneri 2a in laboratory conditions simulating aquatic environment.	information about the duration of survival of shigellae in water is speculative. the present study was undertaken to assess the duration of survival of shigella dysenteriae type 1 and s. flexneri type 2a in the laboratory conditions simulating the aquatic environment, their invasive property and the association of different physico-chemical parameters in the survival process.	2001	12040763
antimicrobial resistance of shigella spp isolated from diarrheal patients between 1989 and 1998 in vietnam.	shigellosis is an important cause of infectious diarrhea in vietnam, caused mainly by shigella flexneri. this study provides for the first time in the international literature, data on the development of antimicrobial resistance in shigella between 1988 to 1998, including data reported to the national program for surveillance of antimicrobial resistance (npsar). our studies show that about 80% of the shigella strains tested were resistant to ampicillin, chloramphenicol, oxytetracycline, trimetho ...	2001	12041563
epidemiological applications: a case report of a village epidemic of gastroenteritis.	this is a case report of an epidemic of gastroenteritis which was investigated and controlled by epidemiological methods only, before laboratory investigations could be done to confirm the original epidemiological conclusions--from contaminated home made ice-cubes. the case and process are reported in order to encourage similar uses of epidemiology by field public health practitioners, especially within the district or primary health care systems and particularly in places where laboratory suppo ...	2001	12017811
death from multi-resistant shigellosis in fiji islands.	death from shigellosis is rare in developed countries, however it causes over a million deaths in developing countries worldwide annually. death from shigellosis is rare in fiji. however, the global problem of emerging multidrug resistance raises some issues about the management of shigellosis in this country. within fiji, shigella is a notifiable disease. the fiji ministry of health recorded 68 cases of shigella in 1996, 173 cases in 1997 and 334 cases in 1998 (no data available for 1999). ther ...	2001	12017845
salmonella, shigella and growth potential of other food-borne pathogens in ethiopian street vended foods.	to evaluate the bacteriological safety of food items sold by street vendors with regard to salmonella and shigella and to assess the growth potential of some foodborne pathogens in some street foods.	2001	12219962
expression of colonization factor antigen i of enterotoxigenic escherichia coli in shigella flexneri 2a t32.	a host-plasmid lethal balancing system was constructed based on asd gene in an avirulent strain of s.flexneri to express colonization factor antigen i(cfa-i) of enterotoxigenic escherichia coli.the results of western blotting suggested that avirulant strain of s.flexneri fwl01 expressed cfa-i steadily. examination of negatively-stained preparation of cultures by electron microscopy showed that s.flexneri fwl01 carrying the plasmid pzhy21 had thick pili on its surface. antibodies against cfa-i we ...	2001	12050785
methods for the preparation and crystallization of fab fragments in complex with peptide antigens derived from n. meningitidis outer membrane proteins.	an understanding of the molecular basis for the recognition of outer-membrane proteins (omps) by antibody is an important goal in the development of a more rational approach to vaccine design. x-ray crystallography has been outstandingly successful in delineating the detailed chemical interactions that are responsible for the high affinity and high selectivity of antibody-antigen interactions (1). although a number of x-ray structures of omps have now been reported (e.g., 2), determination of th ...	2001	21336751
letter: si chaos.		2001	55546
comparison of a new microcrystalline dicoumarol preparation with warfarin under routine treatment conditions.	1 to determine whether two different oral anticoagulants show difference under routine clinical conditions, 71 patients were randomized to treatment with apekumarol, a microcrystalline dicoumarol preparation, and 72 patients to treatment with warfarin. 2 during the inpatient phase of treatment both drug groups remained for about 94% of their treatment time within prothrombin value limits of 5-25% (simplastin a). no statistically significant difference was found between the drugs. 3 while under o ...	2001	95337
primary prevention oregon style.		2001	98505
letter: daunorubicin cardiotoxicity.		2001	55702
psychiatrists with blinkers.		2001	87973
cimetidine for hypertrophic prostate?		2001	88991
symbolic play in language-impaired and normal children.		2001	95236
priapism: current concepts.	the treatment options for the management of the patient with priapism have changed markedly within the past several years. when possible, the underlying cause of the priapism should be identified. therapy should be guided by the results of aspiration of the blood-filled corpora cavernosa of the erect penis. early intervention through pharmacologic manipulation or surgical shunting should not be delayed while trying conservative measures.	2001	2569852
priapism: current concepts.	the treatment options for the management of the patient with priapism have changed markedly within the past several years. when possible, the underlying cause of the priapism should be identified. therapy should be guided by the results of aspiration of the blood-filled corpora cavernosa of the erect penis. early intervention through pharmacologic manipulation or surgical shunting should not be delayed while trying conservative measures.	2001	2569852
caring for the elderly. orienting the new-admission elderly patient to the long-term care facility.		2001	98758
nuclear pacemakers.		2001	95272
instability of cerebral blood-flow in insulin-dependent diabetics.	cerebral blood-flow (cbf) was measured in 23 insulin-dependent diabetics before and 2--3 h after insulin/breakfast. in 10 of these patients cbf changed significantly during the day, with a significant fall in 9. in 3 patients who had the greatest falls in cbf there was a concomitant sensation of an impending faint. thus cbf is unstable in insulin-dependent diabetics in contrast to control subjects in who there is little or no variation. sudden falls in cbf in insulin-dependent diabetics may expl ...	2001	92619
intrathecal methotrexate causing paraplegia in a middle-aged woman.		2001	97902
clinical contribution to the knowledge of hemopoietic dysplasias: long-term follow-up of 13 patients with refractory anemia.	refractory anemia (ra) is an hematologic disorder at risk of developing into a malignancy (hemopoietic dysplasia). information on hemopoietic dysplasias is useful for sharpening the appropriate diagnostic criteria and for the search of an appropriate therapy. moreover, hemopoietic dysplasias provide an interesting opportunity, in humans, for studying a developing leukemia, or a disease situated at the boundary of leukemia. this paper reports on the evolution of ra in 13 patients followed up more ...	2001	97896
galactosyltransferase activities in subcellular fractions of two yc8 lymphoma cell variants : does a relationship exist between antigenic determinants and acceptor sites for galactose?		2001	88962
gastric cancer in patients who have taken cimetidine.		2001	87690
the infrared spectroscopic gram stain.	the attenuated total reflectance (atr) spectra of bacterial colonies were obtained in situ, without their removal from the agar growth media using the infrared microscope. principal components regression (pcr) analysis was used to obtain a measure of the differentiating potential of the atr spectra obtained on two standard sets consisting of 31 and 44 species, respectively, grown on trypticase soy agar. a quantitative response value of +1 was assigned to gram positive species and -1 was assigned ...	2001	11936876
effect of spices and herbs towards shigella sonnei and s. flexneri.		2001	15954300
inhibitory effects of spices and herbs towards shigella sonnei and s. flexneri.	the use of spices and herbs, their essential oils or their active compounds as means of control of pathogens constitutes an alternative to chemical additives in the present study the antibacterial activities of cloves, thyme, oregano, rosemary and basil on shigella have been established. although in a model system in agar media addition of 1% basil could contribute to the 'hurdle' principle and delay outgrowth of shigella sp. this was not confirmed in real food conditions: the presence of 1% bas ...	2001	15954648
[choice of antibiotics by young physicians].		2001	98885
clinical and histological study to assess changes in the nasal mucosa in patients with chronic perennial rhinitis comparing sodium cromoglycate and placebo.	a controlled trial comparing sodium cromoglycate 2% nasal solution against placebo has demonstrated that in patients with severe perennial rhinitis sodium cromoglycate is clinically effective and also that gross histological changes in the nasal mucosa are reversed following treatment for eight weeks with this therapy.	2001	98822
changes in amylase activity in submandibular salivary glands of adult male mice following castration.		2001	95526
tumor-specific immunity induced by somatic hybrids. ii. elicitation of enhanced immunity against the parent plasmacytoma.	hybrid cells derived from fusion of a balb/c plasmacytoma (tepc-15) and l cells (c3h origin) were used to stimulate tumor-specific immunity against the parental plasmacytoma cells. live hybrid cells induced tumor-specific immunity against tepc-15 more effectively than mitomycin-treated hybrid or tepc-15 tumor cells. adoptive transfer of immunity with spleen cells of mice immunized with hybrid cells was also more effective than that with mitomycin-treated tumor cells. the immunity induced by the ...	2001	88483
tissue culture in the inherited corneal dystrophies: possible applications and problems.		2001	60147
chinese hamster purine nucleoside phosphorylase.		2001	99640
cell-mediated immunity: delayed-type hypersensitivity and cytotoxic responses are mediated by different t-cell subclasses.	cell-mediated immunity includes both the generation of cytotoxic cells and initiation of delayed-type hypersensitivity (dth). the resting t-cell population, before stimulation by antigen, already contains cells of the lyl subclass that are programmed to initiate dth (and helper function) but not cytotoxic responses, as well as ly23 cells which can generate killer activity (and suppressive function) but not dth. the central implication of these findings is that the broad division between humoral ...	2001	1083891
[cardiotoxicity of cytostatics in long-term therapy].		2001	98313
trends in pcb contamination in dutch coastal and inland fishery products 1972-1976.		2001	98187
a theoretical model for adhesion between cells mediated by multivalent ligands.	a theoretical model is developed for cell-to-cell binding by bivalent ligands that can bind to mobile receptors on the cell surfaces. monovalent inhibitors that can bind either to receptors or ligands are also included. for symmetrical ligands, that is, ligands in which both binding sites are the same, it is shown that crosslinking of receptors on each cell will interfere with intercellular bridge formation. at equilibrium, such interference is not drastic, but if the crosslinks can form before ...	2001	95173
dietary and dental variations in the genus lemur, with comments concerning dietary-dental correlations among malagasy primates.	field studies of feeding in the lemur subspecies lemur fulvus rufus and l. f. mayottensis have revealed that feeding patterns within a single species can be markedly different, both regionally and seasonally. thus l. f. rufus is a dietary specialist (3 plant species accounting for 80-90% of feeding time), and is highly folivorous, especially during the dry season (90% of feeding time spent eating leaves during the dry season, and 53% during the wet season). on the other hand, l. f. mayottensis i ...	2001	98050
hysterographic double-outlined uterine cavity: a sign of unsuspected pregnancy.	a review of three hysterograms inadvertently performed during early pregnancy reaffirms the regular appearance of infiltration of aqueous opaque media into the substance of the decidua, producing the sign of the double-outlined uterine cavity. although such endometrial opacification may also occur during the late secretory phase, its recognition should arouse suspicion of pregnancy. a coexisting intrauterine filling defect may then be more confidently diagnosed as an amniotic sac.	2001	98013
the biology of ethics or the ethics of biology? the biologist's quest for meaning.	the biologist's involvement in value issues concerning the metholology of biological sciences, in establishing the biological basis of ethics and in creating a value system based on biological knowledge is examined. it is proposed that the roots of this involvement are in the conflict of the knowledge-ethic with the established system of values and in the need for metaphysical explanation.	2001	97886
oestrogen therapy and endometrial carcinoma.		2001	87698
a clinical algorithm for urinary tract symptoms.		2001	97592
chlorinated hydrocarbons (pesticides and polychlorinated biphenyls--pcbs) in the atmosphere of ljubljana.		2001	100082
external iliac artery fibrodysplasia.	clinical and arteriographic features of 12 patients with external iliac artery fibrodysplasia are reviewed. these lesions usually occur in patients having arterial fibrodysplasia elsewhere, attesting to the fact that they represent a generalized arteriopathy. occasionally they occur in association with severe atherosclerosis. external iliac artery fibrodysplasia exhibits the classic corrugated "string-of-beads" angiographic appearance in the majority of patients. the pattern of aneurysmal dilata ...	2001	97963
progress in investigations of sphingolipidoses.		2001	97916
congenital cutis laxa and maternal d-penicillamine.		2001	88570
lithium toxicity with phenothiazine withdrawal.		2001	90797
[pathological study of late arterial spasm (author's transl)].		2001	93249
[the problem of hepatic dysfunction of the diagnosis of hypernephroid kidney carcinomas (stauffer syndrome)].	in 43 patients with histologically proved hypernephroid kidney cancer evaluation of the electrophoretic results, serum alkaline phosphatase, thromboplastin time (quick's time) and bromthalein retention (n = 10) was carried out. as a control group the serum values of 10 patients with clinical tentative diagnosis of hypernephroid kidney cancer were checked; in this group operation and histological examination showed no kidney tumor. only in one patient we found the typical constellation with eleva ...	2001	88402
observations on 160 patients with peripheral facial paralysis seen in private practice.		2001	98678
gas pocket causing pacemaker malfunction.	pacemaker malfunction was attributed to the increase in impedance to current flow caused by a pocket of air separating the anodal contact plate of a unipolar generator from the overlying skin. lack of capture was noted 20 hours after implantation. the malfunction was permanently corrected by bedside aspiration of the gas with a sterile syringe.	2001	95278
"native" salivary chromosomes of drosophila melanogaster.		2001	98275
optimised blood-pressure.		2001	87900
psuedotumor cerebri and insecticide intoxication.	three patients with headache and increased intracranial pressure had elevated blood, serum, and adipose levels of the organochlorine insecticide chlordecone (kepone). these patients were among 23 employees who suffered from chronic chlordecone intoxication resulting from industrial exposure. in our three patients, investigations eliminated an intracranial mass or other known causes of psuedotumor cerebri. in all three patients, the capacity for cerebrospinal fluid (csf) absorption was assessed b ...	2001	90347
the use of pinen for the enlightment and embedment of histochemical preparations treated with azo-dye coupling method.		2001	97908
behaviour of alpha1-antitrypsin in lung cancer.		2001	98836
free school meals and height of welsh schoolchildren.		2001	90776
biochemical and energetic gradients in the mucosa of stomach and duodenum of patients with antral ulcer.	separation and measurement of adenine-adenosine, adenosine monophosphate (amp), adenosine diphosphate (adp), adenosine triphosphate (atp), lipid phosphates, rna and dna, further, separation and measurement of mg2+-dependent, total (mg2+-dependent plus na+--k+-dependent, mg2+-na+-k-dependent) and na+-k+-dependent atpases were carried out in the mucosa and muscles of the corpus, antrum and duodenum of 68 patients with antral ulcer. it was found that (1) the substrate levels of adenosine nucleotide ...	2001	95466
maternal influence upon the v-type gene position effect in drosophila melanogaster.		2001	98705
sodium cromoglycate (intal) in the management of chronic leg ulcers.		2001	98691
[digestive tract and uric acid metabolism].		2001	95363
peroral prostheses for palliating malignant esophageal and gastric obstruction.		2001	90635
radiation from implantable nuclear pacemakers. ii. analysis.		2001	95300
"runaway" in a modern generation pacemaker.	life-threatening episodes of ventricular tachycardia were documented in a patient with an implanted omni-stanicor pacemaker due to episodic pacemaker runaway. the unit generated impulses at rates varying from 73 to 500 per minute. ventricular capture at high rates was variable, but frequently resulted in heart rates in excess of 200 per minute. these episodes were associated with loss of consciousness secondary to inadequate cardiac output. although the pacemaker could be inactivated by reprogra ...	2001	95274
research needs in low vision.	research needs are presented for several areas of low vision: (1) reading and learning, (2) new low-vision aids, (3) modifying the environment, (4) utilization of disciplines, (5) new technologies, and (6) integrating low-vision services.	2001	88182
[successful exclusively tube feeding over a period of 21 months in a cranio-cerebral injury with the apallic syndrome].		2001	99629
pneumomediastinum associated with diabetic ketoacidosis.		2001	99507
[radioimmunologic determination of alpha fetoprotein in high risk pregnancies].		2001	90481
postcentral neurons in hand region of area 2: their possible role in the form discrimination of tactile objects.		2001	98206
the hypostatization of death in adolescence.		2001	90453
role of preoperative urography in benign prostatic hyperplasia.	the excretory urograms of 184 consecutive patients admitted to hospital with a diagnosis of benign prostatic hyperplasia who subsequently underwent prostatectomy were reviewed to determine the usefulness of preoperative urography. of 184 urograms reviewed, 10 were normal, 136 showed changes consistent with benign prostatic hyperplasia, and 38 revealed other abnormalities. twenty-seven of 184 urograms (14.7 per cent) revealed significant pathologic conditions requiring further consideration, inve ...	2001	90420
the hook sign in type 3 congenital colonic atresia.		2001	98027
[conservative therapy of immunodeficient states in children].		2001	90361
neuroendocrine embryology and the apud concept.	in the vertebrata the great majority of cells producing hormonal peptides belong to the apud series and share its distinctive cytochemical and ultrastructural characteristics. according to the concept all members of the series are to be regarded as derivatives of neuroectoderm or of specialized (placodal) ectoderm. for most of the apud cells this criterion is fulfilled in that their origin from neural tube, neural ridges or neural crest can be considered proven. complete proof is not yet availab ...	2001	29734
from earlier pages. . .		2001	97977
[effect of adsorption on the structure and properties of hemoglobin].	adsorption spectra of hb+ and hbo2 adsorbed on silica and monolayers cholesterol supported on silica have been studied. it is shown that immobilization leads to new states of proteins, their properties depending on the nature of support and conditions of adsorption. adsorption of haemoglobin leads to its inactivation. the rate of inactivation decreases with an increase of surface concentration of haemoglobin and with simultaneous adsorption of inert proteins.	2001	29668
infertility in a potto.		2001	97850
intrathecal igg synthesis in multiple sclerosis and other neurological diseases: a comparative evaluation by igg-index and isoelectric focusing.	intrathecal igg synthesis has been investigated by determining the igg index and by isoelectric focusing in 30 cases of definite multiple sclerosis, in 15 cases of probable multiple sclerosis and in 128 patients affected by other neurological diseases. the blood-brain barrier function was evaluated at the same time by serum albumin/csf albumin quotient and isoelectric focusing. the igg index was found elevated in 73.3% of definite multiple sclerosis patients, while oligoclonal igg bands occurred ...	2001	92550
right/left differences of median nerve evoked scalp potentials in multiple sclerosis.	scalp potentials evoked by electrical stimulation of the median nerve at the wrist were examined in multiple sclerosis patients and healthy controls. the latencies of the first negative peak (about 18 ms latency) of the response to right and to left-sided stimulation were compared. forty-eight of 60 measured latency differences in 15 suspected or certain ms patients were more than 3 standard deviations beyond the average difference in controls (arbitrary norm limit), whereas none of the 56 resul ...	2001	92533
thyrotoxicosis in a patient with secondary hypothyroidism.	we have described a patient with panhypopituitarism who developed thyrotoxicosis. there is a widespread belief that pituitary thyrotropin (tsh) is not a pathogenetic factor in most patients with thyrotoxicosis. due to technical reasons, however, it has been difficult to entirely exclude the role(s) of tsh in the development of thyrotoxicosis. in this report hyperthyroidism appeared in a patient with tsh deficiency proved by the lack of response to trh administration. this is the first known case ...	2001	98848