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[possible circulation of r. prowazekii among animals (according to data of serological studies)].the authors present the results of serological studies of the sera obtained from various animal species in the complement fixation test of agglutination with rickettsial antigens, particularly with the r. prowazeki antigen. the proteus ox19 antigen was also used to ascertain the true nature of the positive agglutination test of the sera of domestic animals with the r. prowazeki antigen; immunochemical analysis of the sera in sephadex g-200 gel was employed. agglutinins to the r. prowazeki antige ...1976827160
the binding site of escherichia coli ribosomal protein s4 on 16-s ribosomal rna from different bacterial species.ribosomal protein s4 of escherichia coli was bound to 16-s ribosomal rnas from several bacterial species and the complexes digested with pancreatic ribonuclease in an effort to isolate heterologous rna binding sites for protein s4. 16-s rnas from aeromonas punctata, pseudomonas fluorescens and vibrio cuneatus each gave rise to protected fragments whose electrophoretic mobility was 7s, i.e. similar to that of the fragment generated from e. coli 16-s rna using the same conditions. no comparable fr ...1976827436
[in vitro action and clinical use of indanyl carbenicillin]. 1976827680
[microflora of trophic ulcers]. 1976827841
[elder people in institutions - problems concerning health and hygiene (author's transl)].on the basis of our earlier studies on the hygienic, health and social situation of old people living in their own flats, we investigated the conditions in all 12 larger old people's homes of a big city in the rhine-main area, as well as 100 selected subjects of a defined socio-economic group within these homes. we checked the existence of pathogenic germs and the total number of germs on a total of 247 air culture plates in as many rooms and 669 impression preparations; additionally, we evaluat ...1976827881
[microbiology of chronic lung diseases in children (author's transl)].the bacterial flora was studied in the bronchial, pharyngeal secretions and sputum of 80 children with cystic fibrosis (cf) and of 21 children with other chronic lung diseases, treated at the pediatric clinic (respiratory unit), university of genoa. staphylococcus aureus was found in 52% of patients, pseudomonas aeruginosa in 48%, proteus in 5%. according to the age, the patients have been distinguished into four groups; in the 6-10 and 11-15 year-old group staphylococcus aureus was the commones ...1976827983
[antimicrobical resistance of bacterial strains isolated in specimens of the respiratory tract (author's transl)].more than 4,000 susceptibility tests of antimicrobical agents performed in two years with six groups of microorganisms: 1) staphylococcus, 2) escherichia coli, 3) proteus, 4) enterobacter and klebsiella, 5) citrobacter, 6) pseudomonas aeruginosa, have been compared. percentages of antimicrobical resistance of every group are here related and statistically compared to discover significant susceptibility variations of bacteria isolated in 1973 and 1974.1976827986
in vitro studies with sisomicin and gentamicin.sisomicin and gentamicin were tested in vitro against 222 clinical isolates of pathogenic bacteria using the ics agar dilution procedure. the two drugs were comparable in terms of overall activity although statistical analyses of the data revealed significant differences in their activity against several genera. sisomicin was significantly more active against pseudomonas aeruginosa (p less than 0.001), proteus mirabilis (p less than 0.005), and escherichia coli (p less than 0.01); gentamicin was ...1976821725
therapy of infections with cefazolin.16 patients with acute urinary tract infections, 6 with acute lower respiratory tract infections and 3 with miscellaneous infections were treated with 1 g cefazolin parenterally 3 times daily. all patients, except one in whom therapy was discontinued, were cured. both intramuscular and intravenous administration resulted in high-peak serum levels, and concentrations after 8 h were still inhibitory to relevant pathogens. the drug was well tolerated and caused, after intramuscular injection, proba ...1976821726
[cortisone and liquemin therapy of septic shock in peritonitis]. 1976821728
[studies on the distribution of thienylcarbenicillin in the human tissue].thienylcarbenicillin is another semisynthetic penicillin with a wide range of antibacterial activity including most of gram-negative bacterias, even such as pseudomonas aeruginosa. to investigate penetration activities into bone and another tissues, 120 specimens of serum and 120 specimens of tissue were obtained from 20 patients, after i.v. injection of a single doses of 150 mg thienylcarbenicillin per kg body weight. the evaluation of concentration showed that thienylcarbenicillin was eliminat ...1976821729
[qualitative and quantitative studies of the problem of prosthesis disinfection]. 1976821741
the aerobic flora of the perivaginal area: its relation to contraception and deodorant sprays. 1976821908
identification of the antibiotic determined by the scp1 plasmid of streptomyces coelicolor a3(2).the antibiotic whose biosynthesis is determined by the scp1 plasmid of streptomyces coelicolor a3(2) has been characterized as the recently described methylenomycin a (2-methylene-cyclopentan-3-one-4,5-epoxy-4,5-dimethyl-1-carboxylic acid).1976822125
[indwelling catheter after laparotomy with special reference to retrograde urinary tract infections (author transl)]. 1976822188
[significance of antibody titers in recurrent urinary tract infection in children (author's transl)].2254 antibody titers have been measured by the indirect hemagglutination method in 84 children with recurrent urinary tract infection using single organisms as homologous or several strains from one species (e. coli, proteus, klebsiella, pseudomonas) as polyvalent antigens. increase of homologous antibody titers within 3 weeks following a significant bacteriuria (65% of all cases) has been found to be a more reliable parameter for diagnosis of infection than leukocyturia or clinical symptoms. de ...1976822268
bacterial isolations from canine and feline urine. 1976822272
bactericidal efficacy of sch 20569 and amikacin against gentamicin-sensitive and -resistant organisms.sch 20569 is a semisynthetic derivative of gentamicin with activity against many gentamicin-resistant gram-negative bacilli. we compared its bactericidal action with that of gentamicin and amikacin against 171 clinical isolates of enterobacteriaceae, staphylococcus aureus, and pseudomonas aeruginosa. sch 20569 and amikacin showed markedly greater activity than gentamicin against escherichia coli, klebsiella, enterobacter, citrobacter, and indole-positive proteus, primarily by virtue of their let ...1976817661
pirbenicillin, a new semisynthetic penicillin with broad-spectrum activity.pirbenicillin is a new semisynthetic penicillin which inhibited 67% of isolates of proteus aeruginosa tested in our laboratory, 93% of p. mirabilis, 31% of enterobacter spp., 41% of serratia spp., and 58% of escherichia coli at a concentration of 6.25 mug/ml. its activity appeared to be inoculum dependent and it was virtually inactive against 10(7) inocula of p. aeruginosa. it was more active than carbenicillin or ticarcillin, but less active than bl-p1654 against p. aeruginosa. carbenicillin an ...1976817665
[oxolinic acid therapy of urinary tract infections in infancy]. 1976801102
[resistance patterns of certain enterobacteriaceae in hospital and outpatients, with particular reference to trimethoprim-sulfamethoxazole (author's transl)].the relative sensitivities of certain enterobacteriaceae strains obtained from impatient and outpatient material for investigation against trimethoprim-sulf-amethoxazole, ampicillin, cephalothin, gentamicin and tetracycline are reported. the efficacy of the substances tested was very varied, the resistance rates to gentamicin and trimethoprim-sulfamethoxazole being most favorable. differences in sensitivity could be established between strains from inpatient and outpatient material. resistance r ...1976817195
["in vitro" determination of bacterial sensitivity to tobramycin (author's transl)].the authors report the tobramycin minimal inhibitory concentration (mic) of 264 strains (dilution in mueller-hinton agar). staphylococcus aureus (96 strains) have a mic of 0.02 mcg/ml, 80 % being inhibited by 0.07 mcg/ml. most enterobacteriaceae (70 strains) are sensitive to 0.7 mcg/ml ; providencia are the most resistant (mic 11.88 mcg/ml). among pseudomonas aeruginosa (98 strains, mic : 11.57 mcg/ml) 50 % are inhibited by 0.30 mcg/ml, 80 % by 18.8 mcg/ml. relationships of mic to zone diameters ...1976817253
diversity of beta-lactamase activity among clinical isolates of gram-negative bacilli.various properties (specific activity, inducibility, substrate profile, and susceptibility to inhibitors) of the beta-lactamase activity present in 39 strains of enterobacteriaceae and pseudomonas aeruginosa isolated during a two-month period in the bacteriology laboratory of a large general hospital were investigated. among the 39 strains there appeared to be at least 16 distinct enzymes. most enzymes from escherichia coli, klebsiella pneumoniae, proteus mirabilis, and proteus morganii were act ...1976817594
studies on the antimicrobial activity of amniotic fluid.sixty-one amniotic fluid samples from women in their second and third trimesters of pregnancy were examined for antimicrobial activity. seventy per cent of the fluids were found to be active. the factor or factors responsible for this activity were present in low concentrations. the presence of spermine in the fluids accounted for some of the antimicrobial activity.1976817602
polymicrobic bacteriuria: significant association with bacteremia.current clinical practice states that a urine culture yielding three or more isolates must be considered a contaminated specimen and discarded. the validity of this practice was tested by reviewing all patients at the west haven veterans administration hospital with positive blood cultures for 1 year to determine how many were associated with polymicrobic bacteriuria (two or more urine isolates each present at greater than 10(5) colonies/ml). during 1973 there were 18 patients who had bacteremia ...1976818108
[clinical studies on gentamicin (author's transl)].gentamicin (gm) was studied for on its antibacterial activity, absorption, and excretion, effect on the kidney and clinical effects. the results obtained are as follows: 1. antibacterial activity: the susceptibility of e. coli, klebsiella, proteus mirabilis to gm was almost the same between the periods of 1964 to 1966 and 1972 to 1974: no tendency of increase of resistance by year was noted. however, against pseudomonas aeruginosa, strains showing sensitivity to a concentration of more than 25 m ...1976818417
[change of pathogen in infections since 1958 (author's transl)].infections with proteus, pseudomonas, klebsiella and enterococci have increased significantly in the period of this report. the question of hospital hygiene, especially in intensive care wards, must therefore be given increased attention. uncritical prophylaxis and treatment with antibiotics must be rejected. attempts to improve the cellular and humoral defense of patients with reduced resistance would be worth while. to achieve progress, there must be a close co-operation between specialists in ...1976818523
effect of lanthanum on pinocytosis induced by cations in amoeba proteus.lanthanum chloride (greater than or equal to 10(-5) m) induced pinocytosis in normal and at greater than or equal to 10(-4) m in ca++-deficient amoeba. with respect to the ca++-requirement of the pinocytotic response low and high concentrations of la+++ had effects like na+ and k+, respectively. the concentration of la+++ stimulated or inhibited other types of pinocytosis. thus all concentrations of la+++ inhibited sodium induced pinocytosis while high concentrations (greater than 10(-3) m) stim ...1976818877
[species makeup, biological activity and antibiotic sensitivity of the microbes isolated from patients with a surgical infection].specimens from 227 patients with purulent surgical infections of various localization were tested. the microbial growth was observed in 87.6 per cent of the patients, staphylococci being found in 80.8 per cent of them. the plasma coagulating properties were detected in the staphylococci from 84.2 per cent of the patients among the total number of the staphylococcal isolates. staphylococci were mostly isolated from the patients with osteomyelitis, infected wounds. monocultures of the microbes and ...1976818943
[experimental study of an aerosol preparation containing gentamicin (gentasol)].composition of a suspension aerosol drug, gentasol for local application was developed. it contained gentamycin and prednisolon. the antimicrobial properties of the drug were studied in vitro. it was found that gentasol had a pronounced antimicrobiol effect and inhibited the growth of many microorganisms including cultures resistant to other antibiotics. the drug was active against ps. aeruginosa and proteus, which is an advantage of it as compared to other antibiotic aerosol drugs. the study sh ...1976818945
[antibiotic and chemopreparation sensitivity of the microflora isolated from the bile in inflammatory diseases of the biliary excretory system].the study of sensitivity to some antibiotics and chemotherapeutics of 250 cultures of the main causative agents of the inflammatory diseases of the bile secretion system, i. e. coli bacteria, proteus, ps. aeruginosa and staphylococcus showed that the above microorganisms were in most cases highly resistant to the antibacterial drugs widely used in the clinical practice. the exclusion presented the drugs of the aminoglycoside group and especially gentamycin which had the highest activity. the ana ...1976818947
[experimental study of the antibacterial action of levomycatin in a 40% solution of hexamethylenetetramine].antimicrobial and chemotherapeutic activity of 2 per cent solution of levomycetin in 40 per cent solution of hexamethylentetramine was studied. the preparation was proposed as a new extemporal pharmaceutical form of levomycetin for intravenous administration. it was shown that the bacteriostatic activity of levomycetin in the above pharmaceutical form against microbial cultures sensitive to the antibiotic did not differ from that of levomycetin in the form of an aqueous solution. however, the ba ...1976818951
laboratory evaluation of fr10612, a new oral cephalosporin derivative.fr10612, like cephalexin, is a broad-spectrum oral cephalosporin derivative. the antimicrobial activity of fr10612 against clinical isolates was similar to cephalexin; however, at a low inoculum size its activity was greater than cephalexin against klebsiella pneumonia and proteus mirabilis strains. like cephalexin, the in vitro bactericidal activity of fr10612 was more influenced by the duration of contact with the test organism than by drug concentration. the bactericidal activity of fr10612 a ...1976819411
destruction of ossicles in chronic otitis media.the purpose of this study is to investigate the differences in the destruction of ossicles in chronic ear disease caused solely (monoinfection) by one of the most common three bacteria, namely staphylococcus aureus, pseudomonas aeruginosa or proteus strain. material included 337 cases from 1,093 radically operated ears both with cholesteatoma and without cholesteatoma and in addition cholesteatomatous ears without signs of infection since diagnosed. in 190 ears with cholesteatoma but without dis ...1976819605
identification of beta-lactamases by analytical isoelectric focusing: correlation with bacterial taxonomy.beta-lactamases (ec. 3.5.2.6) can be directly compared by analytical isoelectric focusing. using this technique, 242 strains from five gram-positive and 16 gram-negative genera were examined. a preparation of each strain focused as a single group of bands which did not match the pattern of any r factor-associated beta-lactamase. none of the strains was known to carry an r factor and resistance transfer experiments were unsuccessful. the enzymes studied were therefore thought to be chromosomally ...1976819625
case of anterior urethral diverticulum in male quadriplegic. 1976819659
co-trimoxazole in cases of gram-negative septicaemia. 1976819991
clinical experience with tobramycin in the treatment of infections due to gram-negative bacilli.tobramycin, a new aminocyclitol antimicrobial agent, was administered parenterally to 28 patients infected with gram-negative bacilli. the dosage was 1.5 mg/kg every 8 hours, except in patients with renal insufficiency in whom the dosage interval was 10 times the serum creatinine in hours. serum levels after intramuscular administration were 3.9 +/- 1.6 mug/ml and 1.0 +/- 0.7 mug/ml at 2 and 8 hours, respectively. serum levels after intravenous administration were 4.6 +/- 0.5 mug/ml, 2.3 +/- 0.6 ...1976820195
tobramycin: in vitro and clinical evaluation in 30 patients.clinical evaluation of intramuscular tobramycin was accomplished in 30 patients with respiratory, soft tissue, urinary tract, bone or septicemic infections due to gram negative bacilli. median sensitivity to tobramycin of pseudomonas aeruginosa isolates (19 strains) was 0.62 mug/ml and range 0.31-2.5 mug/ml; less activity was observed for escherichia coli, proteus mirabilis, klebsiella pneumoniae and enterobacter species isolates but median minimum inhibitory concentrations were less than or equ ...1976820196
postoperative bacterial endophthalmitis: section i. 1976820235
in vitro evaluation of cefoxitin and cefamandole.cefoxitin and cefamandole were evaluated in vitro against 263 organisms. studies were performed in mueller-hinton and nutrient broth and agar employing inoculum sizes of 10(6) and 10(8) organisms per ml. at obtainable serum levels both antibiotics were bactericidal for nearly all strains of escherichia coli, klebsiella, proteus mirabilis, and staphylococcus aureus but were inactive against pseudomonas aeruginosa and enterococcus. in agar, cefamandole appeared to be active against most strains of ...1976820241
[antibacterial activity of antibiotics in human bile (author's transl)].marked differences exist between antibacterial activity in human bile and broth. whereas penicillins and cephalosporines exhibit virtually the same activity in broth and bile, tetracycline shows a great lose, and the activity of the aminoglykosides is increased in bile. minimal inhibitory concentrations of chlorampenicol and co-trimoxazole are also different in broth and human bile. the differences in activity are related to the ph although not all deviations can be attributed to the effect of t ...1976820649
comparative evaluation of five aminoglycosides for treatment.gentamicin, tobramycin, sisomicin, amikacin and kanamycin are compared for therapeutic use by correlating the in vitro minimal inhibitory concentration with the in vivo concentration of the antibiotic attainable in the serum at half the time intervall between two administrations of the drugs. using this method of evaluation, e. coli, enterobacter and sensitive strains of the klebsiella and pseudomonas species can be treated in principle equally well with gentamicin, tobramycin and sisomicin, and ...1976820656
topical chemoprophylaxis with silver sulphadiazine and silver nitrate chlorhexidine creams: emergence of sulphonamide-resistant gram-negative bacilli.controlled trials of 0.5% silver nitrate compresses (sn), 1% silver sulphadiazine cream (ssd), and a cream containing 0.5% silver nitrate and 0.2% chlorhexidine digluconate (snc) showed that all were comparably effective in protecting burns from infection. sn compresses were much less active against miscellaneous gram-negative bacilli than the other preparations, and the mean morning and evening temperatures and respiration rates in the patients treated with sn compresses were higher then those ...1976814955
urease. the primary cause of infection-induced urinary stones.previous reports have suggested that urease-producing bacteria play a prominent role in the formation of infection-induced urinary stones. we have carried out crystalization experiments in vitro which show that bacterial urease alkalinizes urine, thereby causing: (i) supersaturation with respect to struvite and calcium phosphate; and (ii) formation of struvite and apatite crystals. growth of proteus in urea-free urine or in urine which contained a urease inhibitor did not cause alkalinization, s ...1976815197
accelerated healing in infected wounds.the effect of a standardized infection of pure and mixed cultures of gram-negative bacteria and a gram-positive coccus was studied in laparotomy wounds of rats. the infections were significantly stronger than in the control group wounds in 14 of 15 comparisons. this increased strength could not be correlated with an increased wound content of collagen. results of histologic studies showed a vigorous inflammatory response which probably was responsible for the increased strength. there was a sugg ...1976816018
[the application of actihaemyl in chronically inflamed and dystrophic urinary bladder (author's transl)].the effect of automated continuous irrigation treatment with actihaemyl on bacterial growth in the infected urinary bladder was tested using an experimental model. the result was that instillation alone of this preparation promoted growth of escherichia coli, proteus mirabilis, and pseudomonas aeruginosa in the infected bladder. with simultaneous application of framycetinsulfate or kanamycin the growth of pr. mirabilis and ps. aeruginosa was totally suppressed in the "urine", and the growth of e ...1976816047
sepsis of urological origin: microbiological aspects. 1976816246
response of neisseria gonorrhoeae to bdellovibrio species.bdellovibrio species are small, highly motile bacteria that are predators upon other bacteria in nature. bdellovibrios attach to, penetrate, replicate within, and destroy prey that share the general characteristic of gram negativity. the lipopolysaccharide moiety of the cell membrane of target microorganisms appears to contain the principal receptor site for bdellovibrio attachment. since gonococci also contain lipopolysaccharide that is similar in many respects to that contained within gram-neg ...1976814101
beta-lactam antibiotics with n-oxide side chains. 1. quinoxaline n-oxides.a series of penicillin derivatives of quinoxaline di-n-oxide carboxylic acids was prepared. these compounds were prepared from the acid chlorides and mixed anhydrides of the quinoxaline di-n-oxides. the compounds prepared exhibited minimal antibacterial activity against gram-negative organisms.1976814237
products from furans. 1. sunthesis and anticoccidial and antimicrobial activity of 5-amino-5,6-dihydro-6-methoxy-2-methyl-2-(4'-biphenylyl)-2h-pyran-3(4h)-ones and related compounds.a michael type addition of an amine to 6-methoxy-2-methyl-2-(4'-biphenylyl)-2h-pyran-3(6h)-one (1) dissolved in ether, benzene, or thf gave 5-amino derivatives of 5,6-dihydro-6-methoxy-2-methyl-2-(4'-biphenylyl)-2h-pyran-3(4h)-one (2). these by subsequent reduction with lialh4 were converted to 5-amino derivatives of 6-methoxy-2-methyl-2-(4'-biphenylyl)tetrahydro-2h-pyran-3-ol (3). both isomers a and b of 1 (in regard to the methoxy group at c6) were used for the synthesis of 2 and 3. the in vit ...1976814239
invitro studies of the effect of bilharcid on urinary tract bacterial pathogens.the antimicrobial effect of an antibilharzial drug "bilharcid" was tested, in vitro, against 51 different strains of bacterial species frequently causing urinary tract infection namely e. coli, staphylococcus aureus, klebsiella, ps. pyocyanea and proteus vulgaris. in addition, the drug was tested against one strain of each of salmonella typhi, salmonella paratyphi a. b and c. minimum inhibitory concentration (m.i.c.) of the drug for each organism, and its bactericidal concentration were determin ...1976801712
[microbiological analysis of vindolinina (an alkaloid isolated from catharanthus roseus) and some of its structural changes].bacteriostatic properties of vindolinina (an alkaloid isolated from catharanthus roseus that has an ester group within its molecule) as well as of its alkaline-hydrolysis product (vindolininic acid) crystallized as chlorhydrate, and of the product of its reduction with lithium and aluminum hydrides (vindolininol) are compared. several strains of bacteria pathogenic to man (proteus, escherichia, shigella, staphylococcus, and pseudomonas) cultured in nutritive-agar dishes containing disks and incu ...1976802793
[is moss and foot an entity or a syndrome? report of a case].dermatological lesions of a patient are studied and investigated. it is suggested that they belong to a syndrome rather than to an entity. the following etiological classification of the mossy syndrome is proposed: due to bacteria, fungi and viruses, and secondary to other dermatopathies. bibliography is reviewed.1976802794
[proticin types of proteus mirabilis strains isolated from various environments]. 1976775565
transferable and non-transferable drug resistance in enteric bacteria from hospital and from general practice.drug resistance to 8 different antibiotics in enterobacteriaceae isolated from different hospitals and two groups of general practitioners was studied. escherichia coli dominated among the 632 strains investigated. drug resistance was found in 62% of the 512 hospital strains and in 38% of the 120 strains from general practice. multiple resistance was common especially in strains from hospital. r factors was found in 23% of the 317 drug-resistant strains from hospital and in 11% of the 46 drug-re ...1976775619
[indanyl carbenicillin in the treatment of urinary tract infections due to difficult urological organisms (author's transl)].fifty in-patients suffering from chronic urinary tract infections with underlying urological diseases received the oral carbenicillin preparation indanyl carbenicillin (short term carindacillin) for 10 days in a dosage of 1 g q.i.d. the therapy results were objectified by blood and urine tests performed prior to and after treatment. indanyl carbenicillin led to a sterile urine in nearly 60% of the patients; in about 85% of the cases the primary organism was eliminated. the drug was particularly ...1976765706
[central venous long-term catheter as potential source of infection in the intensive therapy]. 1976782053
[progress in the prevention and control of urologic complications of the cervix carcinoma. i. urinary tract infections].an investigation was made on patients with cervical carcinoma to test the efficiency of a general administration of antibiotics and chemotherapeutic drugs which are commonly used in urology. the study has been made to analyze the frequency of pathological findings in the urinary tract, in general, and, in particular, the pattern of bacteriological findings as well as antibiogramms at different times of carcinoma therapy. additionally, consideration was given to the bacteriological situation befo ...1976782093
[bacteria of the genus morganella]. 1976782106
[clinical trial of the antibacterial combination sulfamoxole/trimethoprin (cn 3123). fifth communication: comparison of two double-blind studies with cn 3123 undertaken for demonstration of its efficacy (author's transl)].two double-blind trials which, independently, revealed the same conclusion that there is no significant difference between the therapeutic effect of n1-(4,5-dimethyl-2-oxazolyl)-sulfanilamide (sulfamoxole) and 2,4-diamino-5-(3,4,5-trimethoxy-benzyl)-pyrimidine (trimethoprim) (cn 3123, neven, supristol) and a reference preparation, were compared with each other in respect of rating the therapeutic result. the authors discuss the greater occurrence of proteus pathogens at one trial centre, and its ...1976782477
[treatment of peritonitis within the scope septic shock with antibiotics]. 1976782801
[sisomicin versus gentamicin. a comparison of antibacterial and pharmacokinetic properties (author's transl)].in a comparison of the antibacterial in-vitro activity of sisomicin, gentamicin, and tobramycine, sisomicin showed a higher activity against e. coli, indole-positive proteus spp. and organisms of the klebsiella-enterobacter-serratia group, whereas tobramycine was superior against pseudomonas spp. however, the differences in activity between sisomicin and gentamicin were only within one step of dilution which is hardly sufficient to guarantee a basic superiority of one or the other preparation fo ...1976782808
[evaluation of diagnostic parameters in chronic recurrent urinary tract infection in children. iii. pyuria, hematuria, and proteinuria (author's transl)].pyuria, proteinuria and haematuria have been shown to be unreliable parameters for the diagnosis of bacteriuria in 171 children with 455 recurrences of chronic urinary tract infection. bacteriuria caused haematuria in 5%, proteinuria in 18% and even pyuria in only 47% of all instances. pyuria has been also found in 11% of sterile urines. the incidence of pyuria increases with the age of the children and depends on the type of the organisms, but the latter was true mainly in children with obstruc ...1976782812
infections in the surgical departments of a teaching hospital in jerusalem.surveillance of hospital-associated infections at the hadassah university hospital has been carried out since 1970. criteria for infection were defined and were monitored by trained nurse-epidemiologists, with the cooperation of the surgical staff. this report deals with the results of a prospective study of infections present on admission, and those acquired during hospitalization, in six surgical departments between january 1972 and june 1973. of the 7,339 patients discharged, 7.5% acquired an ...1976783080
a rationale for intraperitoneally administered antibiotic therapy.a satisfactory clinical response occurred in 96.7 per cent of 210 patients with proved bacterial peritonitis following appropriate surgical intervention and an antimicrobial regimen of 1 per cent cephalothin administered intraperitoneally, with supplementary antibiotics as indicated. instillation of cephalothin achieves the therapeutic benefits of high intraperitoneal levels with an antibiotic of broad activity and minimum toxicity and permits flexibility in the choice of additional antimicrobia ...1976785645
[study of bacterial allergy in acute appendicitis by the method of leukocyte migration inhibition in vitro].under study was the effect of various bacterial allergens on the migration of blood leucocytes from capillaries in vitro in 23 patients with acute appendicitis and in 18 healthy individuals. bacterial allergens wound suppress leucocytes migration in all patients. most frequently, sensibilization to allergens of hemolytic staphylococcus and hemolytic streptococcus was found. in 4 healthy persons this methods indicated sensibilization to some allergens. the interaction of activity sensibilized ly ...1976785785
[sensitivity of the compensatory hyperthrophic rat-kidney against hematogenous bacterial damage]. 1976785868
[current hospitalismus. contribution to the causal factors of problem infection from the bacteriological view point]. 1976785871
[results in the treatment of anal fistula]. 1976785872
a rapid and sensitive determination of bacterial rrna by means of hybridization-competition. 1976786069
[plasmid determined lactose positive character in (enterobacter hafniae) and (proteus morganii) (author's transl)].the atypical lactose positive characters have been found to be plasmidmediated in 6 strains of enterobacter hafniae and 2 strains of proteus morganii. one of the p. morganii plasmid possesses the fi+ character, all the other plasmids belonging to the fi-group. both plasmids of p. morganii could be transduced and remained then readily transferably by conjugation. two of the e. hafniae plasmids were found unstable when harboured in salmonella typhi grown at 40 degrees centigrade, when they were st ...1976786102
studies of neonatal calf diarrhorea, v. water balances in calves with mixed infections. 1976786441
phospholipid and lipopolysaccharide in proteus mirabilis and its stable protoplast l-form. difference in content and fatty acid composition.cells of the stable protoplast l-form of proteus mirabilis contain 1.5 to 2 times more extractable lipid, mostly phospholipid, per dry weight than cells of the bacterial form. under identical conditions of cultivation the qualitative and quantitiative composition of the phospholipid is very similar in both cell forms. the range of mole percentages of individual phospholipid species is 78-80 for phosphatidylethanolamine, 10-13 for phosphatidylglycerol, 3.9-5.5 for diphosphatidylglycerol and 1.0-2 ...1976786631
[amikacin in urinary tract infections with so-called problem pathogens].amikacin (biklin) was applied in 33 patients with and without renal insufficiency, suffering of non-obstructive inflammations of the urinary tract, caused by multiple resistant hospital germs. the dosage was 125.0--1000.0 mg/die, injected as short infusion and solved in dextrose 5%. the serum and urine concentrations were measured simultaneously. in 18 cases an infection could not be seen after a control period of 8 days up to 4 weeks. persistence of bacteria happened in five cases. reinfection ...1976786834
formation of crystalline deposits by several genera of the family enterobacteriaceae.several species of bacteria from the family enterobacteriaceae formed crystalline materials containing calcium when grown in a defined culture medium. enterobacter aerogenes, proteus vulgaris, citrobacter freundii, and c. intermedius produced calcium pyrophosphate crystals. edwardsiella tarda and escherichia coli formed calcite iii crystals, whereas proteus mirabilis, klebsiella pneumoniae, providencia stuartii, and serratia marcescens produced hydroxyapatite crystals. several of these bacteria ...1976786887
transcription of escherichia coli ribosomal dna in proteus mirabilis.transcription of escherichia coli ribosomal dna introduced into proteus mirabilis on f14 is described. we have developed an assay for e. coli coded ribosomal rna involving fingerprinting of ribonuclease t1 digests of rna isolated from ribosomal subunits. sequence differences in the ribosomal rna of the two species have allowed us to detect e. coli coded 16s, 23s, and 5s ribosomal rna in ribosomal subunits of the e. coli-p. mirabilis hybrid. the proportion of e. coli coded rrna in the hybrid is f ...1976787756
properties of plasmids constructed by the in vitro insertion of dna from rhizobium leguminosarum or proteus mirabilis into rp4.plasmids have been constructed by insertion of dna from rhizobium leguminosarum or proteus mirabilis into rp4 (an r factor of group p). such recombinant plasmids retain the wide host range of the parental plasmid, being as efficiently transmissible as the unmodified rp4 and are stably maintained in rapidly growing cultures. the recombinant plasmids, even though each contained a dna sequence absolutely identical with that of the host strain, are no more efficient at mobilizing the transfer of chr ...1976787766
sensitivity patterns of urinary pathogens in the southland community and a study of sewage flora.the overall sensitivity pattern of the three main urinary pathogens to the commonly used oral antibodies exceeded 80 percent. the incidence of multiple resistant escherichia coli was 8 percent. the resistant patterns of the sewage e. coli resembled that of the resistant urinary e. coli. however only one-third of the resistant urinary e. coli showed multiple resistance whereas two-thirds of the resistant e. coli in the sewage showed this feature. the resistance transfer was low in organisms isola ...1976787846
the anodically-moving thermolabile antigen (ata) of gram-negative bacteria: its function as the receptor for f pili. 1976788356
[the anodically moving thermolabile antigen (ata) of gram-negative bacteria: its molecular heterogeneity and its chemical composition].the anodically-moving thermolabile antigen (ata) of gram-negative bacteria represents a glycolipoprote in. in aqueous solution ata exhibits heterogeneity of the molecular size, the range varying between 2.10(4) and 8.10(5) daltons. in the molecular range between 5.10(4) and 8.10(5) all the molecular states give precipitation lines with the corresponding antisera. it could be shown that all the molecular states of ata are formed by different aggregation of the same subunit with a molecular weight ...1976788362
[clinical study on the assessment of bladder puncture in the diagnosis of urinary tract infections]. 1976788367
long-term study of humoral immune response in patients with chronic pyelonephritis.indirect immunofluorescence was used for the measurement of serum antibody titers against the hemologous urinary strain of infecting organism in patients with a clinical diagnosis of chronic pyelonephritis. the passive hemagglutination technique was employed for comparison. the antibody response of the patients was followed-up for a period of two to four years. in contrast to titers determined by hemagglutination, antibody titers determined by immunofluorescence were found to be persistently ele ...1976788977
[bacteriological studies in outpatients with acute urinary tract infections with particular reference to the resistance spectrum (author's transl)].bacteriological investigation of urinary samples from 1,926 non-hospitalised patients with documented or suspected acute urinary tract infection revealed organisms pathogenic for the urinary tract in 56.4% of the patients, who came from various parts of west germany. prevalent pathogens were e. coli (69%) and proteus mirabilis (14%). e. coli and p. mirabilis demonstrated a low rate of resistance against ampicillin, the cephalosporines, gentamicin, tobramycin, and also against nitrofurantoin, nal ...1976789245
[antimicrobial effectiveness of sisomicin. i: in vitro activity of sisomicin compared with gentamicin, tobramycin, amikacin and kanamycin (author's transl)].the aminoglycosides sisomicin, gentamicin, tobramycin, amikacin and kanamycin are highly active against staphylococci including the penicillinase-positive strains. sisomicin is more effective than amikacin and kanamycin. mixed infections with staphylococci and enterobacteriaceae or pseudomonas aeruginosa are thus on indication for treatment with sisomicin or other aminoglycosides. infections with e. coli, enterobacter, susceptible klebsiella, and susceptible pseudomonas strains can be treated wi ...1976789246
[the liver concentration of cephradin and cephacetril and their elimination in the bile].liver biopsies and serum samples were collected after intravenous application of 2 g cephradin (n = 13) or 2 g cephacetril (n = 11) during surgery. there was no difference in the serum levels of cephradin and cephacetril. 30 min. after i.v. application of cephradin the liver tissue concentration was 72.62 mcg/g. 30 min. after i.v. cephacetril the liver tissue concentration was 5.83 mcg/g. the quotient of liver tissue concentration to serum concentration for cephradin was between 0.36 and 0.83, a ...1976789253
variation in urease activity of endemic hospital strains of proteus rettgeri and providencia stuartii.both urease-positive and urease-negative proteeae isolated from cross-infected patients in the same hospitals and, in three cases, from the same patients were examined for their biochemical reactions and somatic (o-) antigens. all isolates gave the same reactions in 17 biochemical tests and possessed o-antigens characteristic of providenic o-type strains 4 or 17. study of the isolates indicated that endemic strains are capable of undergoing variation in urease activity. in the current classifica ...1976789790
derivation and properties of proteus mirabilis systems for high frequency transduction of streptomycin--sulphonamide and streptomycin-sulphonamide--kanamycin resistances.properties of two transducing systems with phages capable of high frequency transduction (hft) of streptomycin and sulphonamide resistance markers of the v group plasmid r905, and of these markers plus the kanamycin resistance marker derived from a previously described hft phage 5006mhftak, are described. transducing particles of the former phage, named 5006mhftsus, were detected using the replica-plate technique in an ultraviolet-induced lysate of proteus mirabilis strain pm5006 transduced to s ...1976789816
dienes typing of proteus strains isolated from barrier-maintained animals.the possible use of dienes' phenomenon for typing proteus strains as an aid to bacteriological monitoring of barrier-maintained animal units was investigated. it was rare for more than 1 dienes' type to be isolated from an individual animal. a persistent relationship between 1 or 2 diene's types and each strain of animal was demonstrated, although these same types were shown to be capable of causing clinical disease in their normal host. the findings suggest that dienes' phenomenon may be of val ...1976790014
[control of cross infection in intensive care units].quantitative determinations of antibiotic susceptibility established that infections occurring in intensive care units were predominantly exogenous cross infections. the most frequently isolated strains were: klebsiella, enterobacteriaceae, serratia marcescens and proteus mirabilis. the majority of the strains showed multiple resistance. despite adequate antibiotic therapy a number of patients died of the infection. many of the methods of disinfection were found to be inadequate, especially as r ...1976790370
[treatment of wounds after episiotomy. bacteriological findings]. 1976790596
animal models of peritonitis.a reproducible animal model of peritonitis has been developed. it uses standard animals, standardized cultures of bacteria and simple techniques. use of this model would facilitate comparison of data from workers in this field. the use of small rodents permits the use of comparatively large populations for statistical evaluation. the method is cheap and economic of laboratory space and does not require surgical expertise.1976790613
infected aortic bifurcation grafts: experience with fourteen patients.the experience with 14 patients with infected aortic bifurcation grafts has been reviewed. factors which appeared to predispose to infection in 11 patients included "re-do" operations, concomitant cholecystectomy or gastrostomy, and ruptured abdominal aneurysm. a mixture of gastrointestinal organisms was responsible for the infections. the pathogenesis, presentation, and treatment varied according to whether the proximal or distal anastomosis was involved or not. aortoduodenal communications wer ...1976790620
five-day course of antibacterials for uncomplicated urinary infections.fifty-six patients with uncomplicated urinary infections were treated with a five-day course of antimicrobials. fifty-four patients had sterile urine two weeks after termination of the drugs. over a two-year period 8 patients were found to become reinfected.1976790745
[comparative studies with the rapid kcn-test for enterobacteriaceae according to cahan, sechter and ohad (author's transl)].581 strains of enterobacteriaceae (184 of salmonella, 100 of shigella, 31 of citrobacter freundii, 61 of escherichia coli, 40 of klebsiella, 165 of proteus) were investigated in comparison with the kcn-test according to møller and with the rapid kcn-test according to cahan, sechter and ohad. there was found that the results obtained with both methods were identical to 99 percent. in both tests there could be observed that inexplicable differences occur only in two strains of proteus mirabilis. t ...1976790855
neotal mastitis due to proteus mirabilis. 1976790942
human oral defenses against gram-negative rods.gram-negative rods are unusual pharyngeal isolates in normal man, which suggests the presence of effective oral defense mechanisms against these organisms. to understand this protection better, we studied the elimination of gram-negative rods from the mouth after gargle challenge. suspensions of escherichia coli, klebsiella pneumoniae, and proteus mirabilis (108 organisms per ml) were gargled by normal volunteers, and pharyngeal swabs for serial quantitative cultures were taken for 3 hours. init ...1976791034
genetic relatedness in the family enterobacteriaceae.five criteria of genetic relatedness are considered. the first, transfer of plasmids between groups, is frequently not a good criterion, because transfer is possible between all genera of the enterobacteriaceae and also to genera in other families. though transfer to closely related groups is most frequent, host restriction and the properties of the plasmid may influence the transfer frequency as much as the relatedness of the donor and recipient. the second criterion is interspecies recombinati ...1976791071
susceptibility of acinetobacter calcoaceticus var. anitratus (herellea vaginicola) to minocycline.the in vitro activity of minocycline against acinetobacter calcoaceticus var. anitratus (herellea vaginicola) was examined. all strains of a. anitratus were inhibited by minocycline at concentrations of 0.4 mug/ml or less. the strains studied were considerably more susceptible to minocycline than tetracycline. no difference between the susceptibility to minocycline and tetracycline was seen with escherichia coli, klebsiella pneumoniae, enterobacter and proteus sp. a regression line of the log mi ...1976791084
extended monod equation. 1976791389
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