Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| identification of a major growth factor for aids-kaposi's sarcoma cells as oncostatin m. | conditioned medium from human t cell leukemia virus type 2 (htlv-ii)-infected t cells supports the growth and long-term culture of cells derived from acquired immunodeficiency syndrome (aids)-associated kaposi's sarcoma lesions (aids-ks cells). a protein of 30 kilodaltons was purified from conditioned medium that supports the growth of aids-ks cells. the amino-terminal sequence of this protein was identical to the amino-terminal sequence of oncostatin m, a glycoprotein that inhibits the growth o ... | 1992 | 1542792 |
| hiv infection in patients over 55 years of age. | we describe the clinical and epidemiological characteristics of human immunodeficiency virus (hiv) infection in patients greater than 55 years of age at the time of diagnosis and make comparisons with younger hiv-infected patients. patients were selected by stratification according to age (greater than 55 years and less than 40 years) from a large cohort, and information was obtained by review of charts. three samples of younger patients were used for general comparison (sample 1), for analysis ... | 1992 | 1548571 |
| survival of hemophilic males with acquired immunodeficiency syndrome with and without risk factors for aids other than hemophilia. | between january 1, 1981, and june 30, 1990, 1,514 hemophilia-associated acquired immunodeficiency syndrome (aids) cases in males were diagnosed in the united states. in 1,394, hemophilia was reported as the sole risk factor. for an additional 120, other risk factors were reported: of 101 of these, 40 had homosexual/bisexual activity, 53 had a history of intravenous drug use, and 8 had both of these risk factors. we examined the demographic data and the survival data of two principal groups: male ... | 1992 | 1553956 |
| cluster analysis of the metastatic patterns of human immunodeficiency virus-associated kaposi's sarcoma. | kaposi's sarcoma (ks) is a pleomorphic spindle cell lesion whose incidence has markedly increased among patients infected with the human immunodeficiency virus (hiv), especially among those whose primary risk factor is homo/bisexual transmission. the question as to whether ks is even a true neoplasm still remains largely unsettled due to the body of epidemiologic and histologic evidence suggesting an infectious etiology of the lesion. accordingly, very few studies have been published regarding s ... | 1992 | 1555840 |
| hepatobiliary scintigraphy in the diagnosis of aids-related sclerosing cholangitis. | twenty human immunodeficiency virus (hiv)-positive patients were studied who presented with right upper quadrant abdominal pain, with or without abnormal biochemical liver function tests, in whom aids-related sclerosing cholangitis (asc) was suspected. the results obtained from hepatobiliary scintigraphy using 99tcm-iodida were compared with data from endoscopic retrograde cholangiopancreatography (ercp), ultrasound and histological data from liver biopsy or post mortem. 99tcm-iodida was abnorma ... | 1992 | 1557214 |
| hepatobiliary complications in patients with human immunodeficiency virus infection. | human immunodeficiency virus (hiv) infection has been associated with a number of hepatic and biliary tract disorders. case reports, series of liver biopsies, and postmortem studies that examined the hepatobiliary system were retrieved with a medlars search and form the basis of this review. the liver and biliary tract are frequently involved with opportunistic infections (most commonly mycobacteria and cytomegalovirus) and neoplasms (mainly kaposi's sarcoma) in patients with hiv infection. the ... | 1992 | 1558086 |
| increasing impact of hiv infection on hospitalizations in the united states, 1983-1988. | during 1983-1988, hospitalizations of patients with a diagnosis of human immunodeficiency virus (hiv) infection increased from 1.3 to 33.7 per 100,000 persons. we used the national hospital discharge survey, which is based on a representative sample of discharges from nonfederal short-stay hospitals, to describe illnesses among hospitalized patients with hiv infection. of 222,200 such hospitalizations during 1983-1988, most occurred among persons who were 25-44 years of age (79%), white (66%), a ... | 1992 | 1560347 |
| an animal model of kaposi's sarcoma. i. immune status of cd1 mice undergoing dimethyl hydrazine treatment to induce angiosarcomas and other malignancies. | dimethylhydrazine (dmh) induces colonic cancer and angiosarcomas in mice. in order to determine pertinence of mouse angiosarcoma as a model to aids associated kaposi's sarcoma (ks), we investigated if immune dysfunction occurred during tumor development by dmh. outbred cd1 male mice received once weekly dmh a 20 mg/kg body weight dose s.c. for 33 weeks. every two weeks initially and then every week groups of dmh-treated and control animals were sacrificed to determine a) peripheral blood and spl ... | 1992 | 1567154 |
| human t-lymphotropic virus type i-associated myelopathy in patients with the acquired immunodeficiency syndrome. | we describe two cases of serologically confirmed human t-lymphotropic virus type i (htlv-i)-associated myelopathy involving north american men coinfected by the human immunodeficiency virus type 1. our first patient suffered from a gradually progressive spastic paraparesis for 10 years prior to presenting with kaposi's sarcoma, while our second patient developed subacutely progressive spastic paraparesis in the setting of full-blown acquired immunodeficiency syndrome. autopsy examination of the ... | 1992 | 1568747 |
| the concurrent presence of systemic disease pathogens and cutaneous kaposi's sarcoma in the same lesion: histoplasma capsulatum and kaposi's sarcoma coexisting in a single skin lesion in a patient with aids. | the concurrent presence of infectious organisms within cutaneous lesions of kaposi's sarcoma (ks) in persons with the acquired immunodeficiency syndrome (aids) has been demonstrated. we report the first patient with aids in whom both ks and histoplasma capsulatum were documented within the same cutaneous lesion. pathogenic organisms of other fungal, mycobacterial, and viral diseases in ks lesions in other patients seropositive for human immunodeficiency virus are reviewed. possible explanations ... | 1992 | 1569241 |
| detection of human immunodeficiency virus type 1 provirus in mononuclear cells by in situ polymerase chain reaction. | studies of human immunodeficiency virus type 1 (hiv-1) infection have attempted to quantitate the viral load correlate it with the degree of immune deficiency. in one study, only about 1 in 10,000 peripheral-blood mononuclear cells (pbmc) expressed hiv-1, but in other studies, at least 1 in 100 cd4-positive cells was infected and harbored the hiv-1 provirus. | 1992 | 1569974 |
| radiology of aids in the pediatric patient. | the acquired immunodeficiency syndrome (aids) has involved the pediatric age group and is especially prevalent in babies born of mothers who are intravenous drug abusers or prostitutes. approximately 30% of children born to mothers who are seropositive for the human immunodeficiency virus (hiv) will develop hiv infection. there are several important differences in children and adults with aids. the incubation period of the disease is shorter, and initial clinical manifestations occur earlier in ... | 1992 | 1576831 |
| aspiration cytology of lymphocyte-depleted hodgkin's lymphoma in a man infected with the human immunodeficiency virus. a case report. | we describe the case of a 39-year-old, human immunodeficiency virus (hiv)-positive man who was noted to have a chest wall mass on physical examination. fine needle aspiration of the mass showed atypical spindle cells. excisional biopsy of the mass revealed hodgkin's lymphoma with areas of lymphocyte depletion consisting of a proliferation of myofibroblastic cells. the myofibroblastic, lymphocyte-depleted areas in the hodgkin's lymphoma mass corresponded to the spindle cells seen in the aspirate. ... | 1992 | 1580125 |
| kaposi's sarcoma associated with adult t-cell leukaemia. | 1992 | 1581223 | |
| perineal manifestations of hiv infection. | individuals who are seropositive for the human immunodeficiency virus (hiv) frequently have disorders affecting the anorectum, yet little has been reported on this subject. we reviewed our initial experience with patients with hiv referred to the division of colon and rectal surgery. forty patients (age range, 19-45 years; mean, 32.2 years) were seen between 1985 and 1989. the mean duration of symptoms was six months (range, one week to six years). in 25 patients (63 percent), more than one anor ... | 1992 | 1582350 |
| anorectal lesions in human immunodeficiency virus-infected patients. | in a prospective study, we analysed the anorectal lesions observed in 148 human immunodeficiency virus-infected patients and compared the data with those reported in the literature. the majority of the patients (97.3%) were homosexual or bisexual men. the mean age of the population was 34.2 years. a history of previous sexually transmitted diseases was found in 79.7% of the male patients. the stage of hiv-related disease, according to the centers for disease control classification, could be dete ... | 1992 | 1588221 |
| aids-associated kaposi's sarcoma and the mechanisms of interferon alpha's activity; a riddle within a puzzle. | as yet, the pathogenesis of kaposi's sarcoma in the context of the acquired immunodeficiency syndrome (aids) is not completely understood; this is also true for the mechanisms of action of interferon-alpha against this tumour. the present review focuses on recent developments that may provide some further insight into these issues. these include the angiogenesis of the tumour and the possible role of growth factors, such as the hiv-transactivating (tat) gene product and interleukin-6, the possib ... | 1992 | 1588254 |
| basal cell and squamous cell carcinoma and kaposi's sarcoma. | the mortality rate of nonmelanoma skin cancer is higher than generally considered. an actual nonmelanoma skin cancer is a risk factor not only for other skin cancers but also for cancers in other organs. the recurrence rate can, according to the method of calculation, yield surprisingly diverging results. statistical mapping of subclinical tumor growth in basal cell carcinoma supplies the margins for tumor-free excision. an even better but more expensive tool for therapy planning is tumor imagin ... | 1992 | 1591311 |
| evidence for a sexually transmitted cofactor for aids-related kaposi's sarcoma in a cohort of homosexual men. | we examined factors associated with the subsequent development of aids-related kaposi's sarcoma in a cohort of 353 homosexual men infected with human immunodeficiency virus (hiv). cumulative incidence curves for the development of kaposi's sarcoma and opportunistic infection were stratified over a wide range of variables at enrollment, including those related to demographics, sexual behavior, illicit drug use, and medical history. we found no strong associations between any of these variables an ... | 1992 | 1591318 |
| recent development of studies on traditional chinese medicine in prophylaxis and treatment of aids. | who statistics indicated that as of october 1, 1991 there were 418,403 acquired immunodeficiency syndrome (aids) patients in the world, and an estimated 5-10 million persons infected with the human immunodeficiency virus (hiv) were at risk of developing aids. 50% of aids victims have died. it has been reported that after 1 year of clinical use hiv could develop resistance to azt (azidothymidine), the only effective drug used worlwide and recommended for clinical use by the us government. aids ... | 1992 | 1597994 |
| [the clinico-pathogenetic characteristics of kaposi's sarcoma]. | the paper is concerned with clinicomorphological characteristics of endemic, immune and epidemic (aids-associated) forms of kaposi's sarcoma (ks). recent experimental and clinical evidence suggests pathogenic contribution to ks of virus-induced depression of sex-linked genes and immunosuppression. combined action of these factors should be regarded when specifying current presentation of ks. | 1992 | 1608201 |
| occult alveolar haemorrhage in bronchopulmonary kaposi's sarcoma. | evidence of occult alveolar haemorrhage was sought by perls's staining of bronchoalveolar lavage fluid to detect haemosiderin laden macrophages in 63 human immunodeficiency virus positive (hiv-1) men who underwent bronchoscopy. twenty three patients had bronchopulmonary kaposi's sarcoma; occult alveolar haemorrhage was present in 16 of these (including two in whom no tracheobronchial lesions were evident at bronchoscopy, but in whom the diagnosis was confirmed at necropsy). forty patients had ot ... | 1992 | 1624606 |
| [pulmonary lesions of acquired immunodeficiency syndrome--analysis of 24 japanese autopsy cases with aids]. | the pulmonary lesions were studied in 24 autopsy cases of japanese patients with aids. the major pathological findings were opportunistic infections, which were the major clinical symptoms in some patients. the pathogens identified were as follows; pneumocystis carinii (pc) in 10, cytomegalovirus (cmv) in 14, atypical mycobacterium in 5, cryptococcus in 2, candida in 2, and nocardia in 1. pc pneumonia was prominent in 8 cases and was the cause of death. in such patients, the lung were heavy and ... | 1992 | 1630037 |
| interferon-alpha, zidovudine, and granulocyte-macrophage colony-stimulating factor: a phase i aids clinical trials group study in patients with kaposi's sarcoma associated with aids. | to increase the hematologic tolerance of interferon-alpha (ifn alpha) and zidovudine combination therapy by the addition of granulocyte-macrophage colony-stimulating factor (gm-csf), and to evaluate the safety, tolerance, and potential efficacy of the combination in patients with kaposi's sarcoma and aids. | 1992 | 1634925 |
| multicentric kaposi's sarcoma in a 5-year-old human immunodeficiency virus-negative renal allograft recipient. | we describe the clinical and pathologic features of a case of pediatric multicentric kaposi's sarcoma (ks) associated with allograft transplantation in a human immunodeficiency virus (hiv)-negative child. a lethal polyadenopathic and visceral ks occurred in a 5-year-old caribbean boy who had undergone an allogenic renal transplantation for diffuse mesangial sclerosis with end-stage renal failure 4 months previously. the hiv-1 and hiv-2 serologies were negative. despite its rarity, ks must be con ... | 1992 | 1644441 |
| [characteristics of human immunodeficiency virus infection in the san juan de dios general hospital]. | a prospective clinical study was conducted between january 1991 and june 1992 of 92 hiv seropositive patients attending the adult outpatient clinic of the san juan de dios general hospital in guatemala city. 52 of the patients met the us centers for disease control clinical criteria for aids. limitations in the diagnostic and laboratory facilities of the hospital hampered identification of some opportunistic infections. 74 of the 92 patients were male. 3 of the 18 infected women gave birth du ... | 1992 | 12290621 |
| some clinical aspects of hiv infection in africa. | an update on clinical aspects of hiv in africa highlights new proposed clinical definitions of adult aids and of tuberculosis in hiv+ adults, and staging of adult hiv infection. the 1986 who clinical definition of aids has been widely used in africa, but now research suggests that this definition has several limitations: the definition will pick up several unrelated diseases such as diabetes mellitus and renal failure. it does not ascertain cases of aids marked by nonopportunistic infections. ... | 1992 | 12317768 |
| monoclonal immunoglobulins in patients with renal transplants: characterization, evolution and risk factors. | gammopathies were found to be present in 25 (13%) of 192 hiv-negative renal transplant recipients with more than 30 months follow-up prospectively investigated for monoclonal or oligoclonal immunoglobulins (mig) by agarose gel electrophoresis and immunofixation. eleven patients had only one monoclonal band, whereas 14 had two or more bands. of these bands, 60% were igg kappa, 29% igg lambda and 11% igm lambda or kappa, and 90% did not exceed 2 g/l. most gammopathies occurred early post-transplan ... | 1992 | 14621723 |
| interferon-alpha in malignant and viral diseases. a review. | in the 35 years since the discovery of interferon, significant biological activity has been described for interferon-alpha (ifn alpha) in various cancers, particularly haematological malignancies such as hairy cell leukaemia and chronic myelogenous leukaemia. except for localised therapy in bladder and ovarian cancer, activity against most solid tumours has been disappointing. other notable exceptions include kaposi's sarcoma, renal cell carcinoma and malignant melanoma, tumours known to be susc ... | 1993 | 7681371 |
| clinical pharmacology of zidovudine and other 2',3'-dideoxynucleoside analogues. | since the discovery of the acquired immunodeficiency syndrome (aids) in 1981, considerable progress has been made in the development of agents with anti-hiv activity. zidovudine was one of the first 2'-3'-dideoxynucleosides to cause inhibition of human immunodeficiency virus (hiv) replication in vitro, by inhibiting the viral reverse transcriptase. early trials showed that zidovudine results in clinical and immunological improvements and prolonged life in patients with aids or aids-related compl ... | 1993 | 7685214 |
| administration of pentosan polysulfate to patients with human immunodeficiency virus-associated kaposi's sarcoma. | neovascularization induced by basic fibroblast growth factor (basic fgf) or fgf-like cytokines is thought to play a substantial role in the pathogenesis of human immunodeficiency virus (hiv)-associated kaposi's sarcoma. pentosan polysulfate has been shown to inhibit basic fgf and fgf-like dependent tumor growth both in vitro and in vivo. moreover, it has been found to inhibit the growth of kaposi's sarcoma-derived spindle cells in vitro. these observations suggested that pentosan polysulfate mig ... | 1993 | 7692072 |
| zidovudine. an update of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy. | zidovudine remains the mainstay in the treatment of patients infected with human immunodeficiency virus (hiv). the drug delays disease progression to acquired immunodeficiency syndrome (aids) and to aids-related complex (arc), reduces opportunistic infections, and increases survival in patients with advanced hiv infection. there is evidence to suggest that zidovudine also delays disease progression in patients with mild symptomatic disease. although one study has shown zidovudine to have no sign ... | 1993 | 7693435 |
| chemotherapy for patients with pulmonary kaposi's sarcoma: benefit of filgrastim (g-csf) in supporting dose administration. | kaposi's sarcoma (ks) is common in individuals infected with the human immunodeficiency virus (hiv-1). although ks is frequently indolent, it can also be aggressive and life-threatening, especially in patients with pulmonary involvement (pks), who have poor survival rates when untreated. in an effort to develop treatment regimens for pks that would prolong life or reduce clinical symptoms, we used combination chemotherapy to treat 18 patients who had aids and pks; 13 (72%) of them had a history ... | 1993 | 7694375 |
| changes in survival after acquired immunodeficiency syndrome (aids): 1984-1991. | in a prospective cohort of 2,647 human immunodeficiency virus type 1 (hiv-1) seropositive homosexual men enrolled in baltimore, chicago, los angeles, and pittsburgh, 891 developed clinical acquired immunodeficiency syndrome (aids) between june 1984 and january 1992. cox proportional hazards models were used to examine temporal trends in survival after aids for specific diagnoses, controlling for level of immunosuppression at diagnosis, age, race, and geographic location. median survival time fol ... | 1993 | 7903022 |
| human retroviruses and neoplastic disease. | human retroviral infections result in significant neoplastic disease. human t cell lymphotropic virus i (htlv-i), the first human retrovirus to be discovered, is associated with the development of acute t cell leukemia with characteristic hypercalcemia and skin lesions after many years of chronic infection of cd4+ cells. htlv-i also produces myelopathy. a minor t cell immunodeficiency occurs in htlv-i acute t cell leukemia with associated strongyloidiasis and pneumocystis carinii pneumonia. huma ... | 1993 | 7903870 |
| successful treatment of kaposi's sarcoma with interferon-alpha in a patient with acquired immunodeficiency syndrome. | although combined therapy with interferon-alpha and zidovudine may be safely administered to some patients with the acquired immunodeficiency syndrome (aids) and kaposi sarcoma, no ethnic chinese patient has been successfully treated before in this area. this case report concerns a 47-year-old male with a history of bisexuality who had suffered from oral ulcers for half a year, human immunodeficiency virus (hiv) serology was positive, and pathology of the oral ulcers disclosed kaposi sarcoma. co ... | 1993 | 7907542 |
| trends in the incidence of outcomes defining acquired immunodeficiency syndrome (aids) in the multicenter aids cohort study: 1985-1991. | incidence of clinical outcomes defining acquired immunodeficiency syndrome (aids) may be expected to change as a consequence of progressive immunosuppression and use of chemoprophylaxis before the onset of aids. using poisson regression methods, we examined trends in the incidence of initial and secondary aids-defining illnesses from 1985 to 1991 among 2,627 homosexual men participating in the multicenter aids cohort study who were seropositive for human immunodeficiency virus type 1. the incide ... | 1993 | 8096356 |
| correlation of oncostatin m secretion by human retrovirus-infected cells with potent growth stimulation of cultured spindle cells from aids-kaposi's sarcoma. | oncostatin m (om), a 30-kda glycoprotein, recently was identified as a major growth-promoting factor in the conditioned medium (cm) of the 38-0 cell line, a cd4,+ chronically human t lymphotropic virus type (htlv)-ii-infected, transformed t cell line. cm 38-0 induced the proliferation of spindle cells cultured in vitro from aids-associated kaposi's sarcoma (aids-ks) cells. to determine how much of the aids-ks cell growth activity present in 38-0 cm was because of the presence of om, we depleted ... | 1993 | 8098726 |
| human immunodeficiency virus-associated oral kaposi's sarcoma. a heterogeneous cell population dominated by spindle-shaped endothelial cells. | cell lineage and cell function antigens were studied immunohistochemically in human immunodeficiency virus-associated oral kaposi's sarcoma to provide insight into tumor pathogenesis. all tumors were composed predominantly of spindle cells that expressed endothelium-associated antigens, cd34 and cd36 (factor viii-related antigen was expressed by considerably fewer numbers of tumor cells). infrequently, spindle tumor cells also expressed actin. factor xiiia positive spindle and dendritic stromal ... | 1993 | 8100400 |
| cancer and viruses. | viruses implicated in the development of human cancers include hepatitis b (and c) viruses in hepatocellular carcinoma; human papillomaviruses in anogenital cancers; epstein-barr virus in nasopharyngeal carcinoma and burkitt's lymphoma; human t-cell leukaemia/lymphoma viruses in adult t-cell leukaemia/lymphoma; and indirectly, human immunodeficiency viruses in kaposi's sarcoma and b-cell lymphoma. together, they contribute significantly to the cancer statistics in the southeast asian region. neo ... | 1993 | 8103316 |
| [isolated rectal kaposi's sarcoma]. | we report a case of isolated rectal kaposi's sarcoma in a homosexual man with active human immunodeficiency virus infection. although gastrointestinal tract affection is not infrequent, it is usually associated with the existence of skin lesions. a few cases of noncutaneous gastrointestinal kaposi's sarcoma have been described, but no one affecting only the rectum. this is a diagnostic possibility in patients with human immunodeficiency virus infection and rectal symptoms. | 1993 | 8129997 |
| [bacillary angiomatosis. a pseudoneoplastic infection in aids patients]. | bacillary angiomatosis is a newly recognized pseudoneoplastic vascular disease seen in the setting of human immunodeficiency virus (hiv) infection. the disease is characterized by a cutaneous infection with reddish papules or nodules that are similar to pyogenic granulomas or kaposi's sarcoma in clinical appearance. it is caused by the mildly gram-negative bacillus rochalimaea henselae, which can be identified in tissue sections by means of warthin-starry stain. the historical, clinical, histopa ... | 1993 | 8335458 |
| aids-related malignancies: the emerging epidemic. | the incidence of three malignancies has increased in conjunction with the epidemic of human immunodeficiency virus (hiv) disease, and they are currently considered acquired immunodeficiency syndrome (aids)-defining conditions. these are kaposi's sarcoma, associated with aids since the onset of the epidemic in 1981; intermediate or high-grade b-cell lymphoma, which became aids-defining in 1985; and cervical carcinoma in hiv-infected women, formally recognized as an aids-defining diagnosis on janu ... | 1993 | 8350362 |
| [cutaneous manifestations of aids]. | hiv destroys the immune system, causing group of clinical signs which are referred to as aids. some of these signs are cutaneous in nature. an acute rash on the trunk is associated with hiv seroconversion. it usually disappears in 8 days but can last for several hours or 30 days. infectious manifestations of hiv infection are common. candidiasis represents 90% of mycoses. it usually manifests on the tongue but can also occur on oral or genital mucosa. antifungal medication usually treats it ... | 1993 | 8351723 |
| composite risk score for kaposi's sarcoma based on a case-control and longitudinal study in the multicenter aids cohort study (macs) population. | the possibility that an agent in addition to human immunodeficiency virus type 1 may be involved in the etiology of kaposi's sarcoma in acquired immunodeficiency syndrome (aids) patients was investigated between 1984 and 1992 in this nested case-control analysis from the multicenter aids cohort study (macs) of homosexual and bisexual men. a total of 316 cases of kaposi's sarcoma were identified and compared with 510 participants with aids and no evidence of cancer. more of the kaposi's sarcoma c ... | 1993 | 8356966 |
| epidemiologic analysis of kaposi's sarcoma as an early and later aids outcome in homosexual men. | the authors separately studied the epidemiology (risk and risk factors) of kaposi's sarcoma occurring as an initial acquired immunodeficiency syndrome (aids) outcome (early kaposi's sarcoma) and later after a different initial aids outcome (later kaposi's sarcoma) in a cohort of 2,591 human immunodeficiency virus type 1-infected gay men of the multicenter aids cohort study between 1984 and 1992. among 844 aids cases, 202 presented with early kaposi's sarcoma, 101 subsequently developed later kap ... | 1993 | 8356967 |
| survival and mortality patterns of an acquired immunodeficiency syndrome (aids) cohort in new york state. | the survival experience and causes of death of acquired immunodeficiency syndrome (aids) patients were studied using a cohort of 3,699 aids patients in new york state, excluding new york city, whose illness was diagnosed before january 1990 at age 13 years or older. the median length of survival for all cases was 11.5 months, and survival increased over time from 5.3 months pre-1984 to 9.3 months in 1984-1986 and to 13.2 months in 1987-1989. in a cox proportional hazards model, risk of dying was ... | 1993 | 8356973 |
| spinal epidural leiomyoma occurring in an hiv-infected man. case report. | a case of spinal epidural leiomyoma is reported in a 52-year-old man infected with the human immunodeficiency virus (hiv). the tumor arose in the epidural region at the t-3 vertebral level, and the patient presented with radicular pain in the right t-3 dermatome. while soft-tissue tumors such as kaposi's sarcoma and lymphomas have been well documented in association with hiv infection, this is the first reported case of primary spinal leiomyoma. isolated cases of leiomyomas and leiomyosarcomas i ... | 1993 | 8360744 |
| cancer incidence trends in women at high risk of human immunodeficiency virus (hiv) infection. | to determine the types and rates of tumors which may be associated with hiv infection in women, we used cancer incidence data from new york and northern new jersey. we examined changes in incidence of selected cancers in women aged 20-49 years and compared groups differing in incidence of aids. black women were compared to white women in new york city and in the remainder of new york state; for cervical cancer, rates were also compared for blacks and whites in northern new jersey. the incidence ... | 1993 | 8370617 |
| human immunodeficiency virus type 1 and cytomegalovirus in saliva. | the aim of this study was to evaluate whether hiv-1 or cytomegalovirus (cmv) may contribute to oral lesions frequently found in patients with the acquired immunodeficiency syndrome (aids). saliva samples from 63 hiv-1 positive patients and 21 healthy controls were tested for the presence of hiv-1 and cmv using the polymerase chain reaction (pcr) and virus isolation. cmv igg titres in serum were also compared in the different groups. hiv-1 rna, but not dna, was detected in saliva from 15% (9 out ... | 1993 | 8387571 |
| endothelial cell migration and invasiveness are induced by a soluble factor produced by murine endothelioma cells transformed by polyoma virus middle t oncogene. | polyoma virus middle t-transformed murine endothelioma cell lines provide a useful model for studying vascular lesions such as hemangiomas, hemangiosarcomas, and kaposi's sarcoma and tumor-associated angiogenesis. in vivo they produce fast-growing, hemorrhaging, cavernous blood-filled hemangiomas, mainly formed by recruited host endothelial cells, suggesting an angiogenesis-like process underlying the lesion. the molecular mechanism(s) responsible for the recruitment of host endothelial cells by ... | 1993 | 8393382 |
| multiple primary gynecologic neoplasms in a young hiv-positive patient. | immune suppression from human immunodeficiency virus (hiv) infection is frequently associated with the development of certain neoplasms, including kaposi's sarcoma and non-hodgkin's lymphoma. a young patient with a 5-year history of hiv infection was found simultaneously to have invasive carcinoma of the breast, microinvasive carcinoma of the cervix, and intraepithelial neoplasia of the vulva. in view of the early nature of these neoplasms, conservative therapy was utilized; lumpectomy and adjuv ... | 1993 | 8393503 |
| clinical manifestations of 174 aids cases in maharaj nakorn chiang mai hospital. | the human immunodeficiency virus (hiv) has, since it was first reported in 1981, become a worldwide epidemic. the immunosuppressive nature of hiv results in opportunistic infections, neoplasms, and other pathological conditions. clinical manifestations of these conditions are often the first indication that an individual is infected with hiv. this article reports and describes the clinical findings for 174 hiv-positive patients and is intended to educate thai physicians concerning the rising ... | 1993 | 8408918 |
| indium-111-labeled polyclonal human immunoglobulin: identifying focal infection in patients positive for human immunodeficiency virus. | pooled human immunoglobulin labeled with indium-111 (111in-higg) was used to identify the presence and extent of infection in patients positive for human immunodeficiency virus (hiv), presenting with either symptoms and/or signs of acute chest infection or with pyrexia without localizing signs or symptoms. fifty-five studies were performed in 51 patients with suspected chest infection or pyrexia without localizing signs. of these, 111in-higg identified intrapulmonary accumulation in 17 patients ... | 1993 | 8410271 |
| resting energy expenditure and weight loss in human immunodeficiency virus-infected patients. | resting energy expenditure (ree) and body composition were investigated in 60 clinically stable patients with human immunodeficiency virus (hiv) infection varying with respect to immune impairment. rees differed significantly from predicted values (> or < 10% of the harris-benedict [hb] equation) in 40% of patients. seven percent of patients showed markedly increased ree (> +20% of hb prediction), whereas ree was decreased in 13% (< -10%). increased ree was found during all clinical stages of th ... | 1993 | 8412772 |
| release, uptake, and effects of extracellular human immunodeficiency virus type 1 tat protein on cell growth and viral transactivation. | during acute human immunodeficiency virus type 1 (hiv-1) infection or after transfection of the tat gene, tat protein is released into the cell culture supernatant. in this extracellular form, tat stimulates both hiv-1 gene expression and the growth of cells derived from kaposi's sarcoma (ks) lesions of hiv-1-infected individuals (aids-ks cells). tat protein and its biological activities appear in the cell supernatants at the peak of tat expression, when the rate of cell death is low (infection) ... | 1993 | 8416373 |
| hiv and malignancy. | although a number of tumors in patients infected with the human immunodeficiency virus have been reported, kaposi's sarcoma and non-hodgkin's lymphoma remain the two principal malignancies. this article provides an australian perspective of the recent advances in research into malignancy in hiv-infected persons. | 1993 | 8426302 |
| the spectrum of acquired immunodeficiency syndrome (aids)-associated malignancies in san francisco, 1980-1987. | population-based disease registries for acquired immunodeficiency syndrome (aids) and cancer were linked for san francisco residents to study the pattern of aids-associated malignancies diagnosed during the time period 1980-1987. a total of 1,756 newly diagnosed malignancies were identified during these years among members of the aids cohort. of these, 1,752 (99.7%) occurred in males, 1,454 (83%) were kaposi's sarcoma, 235 (13%) were non-hodgkin's lymphoma, and 16 (1%) were hodgkin's disease. th ... | 1993 | 8434570 |
| esophageal disease in aids is associated with pathologic processes rather than mucosal human immunodeficiency virus type 1. | twenty-five patients with aids and esophageal symptoms were evaluated for the presence of esophageal disease and human immunodeficiency virus type 1 (hiv-1) in the esophageal mucosa. a single infectious process caused by candida albicans, cytomegalovirus, herpes simplex virus, varicella-zoster virus, or mycobacterium avium-intracellulare complex or a single noninfectious process caused by kaposi's sarcoma or reflux esophagitis was identified in 20 patients. two processes were identified in 5 pat ... | 1993 | 8440925 |
| kaposi's sarcoma. epidemiology, pathogenesis, histology, clinical spectrum, staging criteria and therapy. | the acquired immunodeficiency syndrome (aids) epidemic has had a profound impact on our understanding of kaposi's sarcoma (ks). epidemiologic features suggest a sexually transmitted cofactor in the pathogenesis of aids-associated ks (aids-ks), and several putative agents have received intense scrutiny. cell culture studies suggest that the angiogenesis of aids-ks is stimulated by both human immunodeficiency virus proteins and growth factors that may be involved in the development and progression ... | 1993 | 8445054 |
| aids-associated kaposi's sarcoma in romanian children. | kaposi's sarcoma (ks) is commonly associated with the acquired immunodeficiency syndrome (aids) in adults. little is known regarding its occurrence in children. | 1993 | 8445061 |
| [photodynamic therapy of skin tumors]. | photodynamic therapy (pdt) is still an experimental modality using red light in conjunction with a systemic or topical photosensitizer. the photosensitizers have a longer retention time in malignant tumors compared with the normal surrounding tissue. irradiation with a red light at wavelength of 630 nm results in photochemical generation of cytotoxic singulet oxygen. the systemic sensitizer mostly used is hematoporphyrin derivative (hpd) and the light sources are argon-pumped dye lasers, gold va ... | 1993 | 8449696 |
| kaposi's sarcoma in a human immunodeficiency virus-negative patient with asymptomatic human t lymphotropic virus type i infection. | 1993 | 8450265 | |
| [epidemic kaposi's sarcoma in women: presentation of 4 cases]. | epidemic kaposi's sarcoma is the neoplasm most frequently manifested in infection by the human immunodeficiency virus. its prevalence is considerably higher among homosexual males than among intravenous drug users with practically exclusive infection in this sex. four cases of kaposi's sarcoma in women with the human immunodeficiency virus are described. two of these subjects were intravenous drug users and the other two were heterosexually promiscuous as the only conduct of risk for acquiring i ... | 1993 | 8450697 |
| [kaposi's sarcoma and portal hypertension in human immunodeficiency virus infection]. | 1993 | 8452969 | |
| bowenoid changes in kaposi's sarcoma. | previous reports have documented the coexistence of multiple infectious organisms or kaposi's sarcoma within the same biopsy specimens of mucocutaneous lesions in human immunodeficiency virus- (hiv) infected patients. | 1993 | 8454785 |
| [kaposi's sarcoma with pulmonary involvement in a heterosexual man seronegative for the human immunodeficiency virus]. | 1993 | 8464263 | |
| hiv-1 infection and modulation of cytokine and growth factor expression in kaposi's sarcoma-derived cells in vitro. | hiv-1 transcripts have been detected in aids-related kaposi's sarcoma (ks) tissues within the factor xiiia + dermal dendrocytes present in the tumor. various cytokines and growth factors have been shown to influence the growth of ks-derived cells in vitro. hiv-1 preferentially infects cd4+ cells and has also been found to infect some cd4- cells in vitro. the susceptibility of cultured ks cells in vitro to infection with hiv-1 and the expression of interleukin (il)-1 beta, il-6 and basic fibrobla ... | 1993 | 8471192 |
| acquired immunodeficiency syndrome-like illness associated with systemic mycoplasma fermentans infection in a human immunodeficiency virus-negative homosexual man. | a 35-year-old homosexual man developed a composite nodal kaposi's sarcoma and peripheral t-cell lymphoma that were associated with a peripheral blood cd4-positive lymphocyte count of only 43/mm3. the patient subsequently developed pneumocystis carinii pneumonitis and eventually died due to disseminated cryptococcus neoformans. numerous premortem tests for the presence of human immunodeficiency virus (hiv) types 1 and 2 were negative by the enzyme-linked immunosorbent assay, western blot, viral i ... | 1993 | 8491493 |
| kaposiform hemangioendothelioma of infancy and childhood. an aggressive neoplasm associated with kasabach-merritt syndrome and lymphangiomatosis. | we report the clinical and pathological features of nine distinctive, but relatively unknown, vascular tumors of infancy and childhood presenting as soft tissue masses often associated with locally aggressive disease, lymphangiomatosis and kasabach-merritt syndrome. the patients, four males and five females, were all in their first decade of life except for two (median, 2 years; range, 5 months to 19 years). these tumors involved deep soft tissues of the upper extremity (four cases), retroperito ... | 1993 | 8494101 |
| cloned spindle and epithelioid cells from murine kaposi's sarcoma-like tumors are of endothelial origin. | kaposi's sarcoma (ks) is a complex neoplasm comprising spindle cells, vascular structures, erythrocytes, and an inflammatory infiltrate. the pathogenesis of this disorder is not yet understood, which is a major impediment to the design of safe and effective new therapies. we previously reported a murine model in which simian virus 40 (sv40) t-antigen-transformed murine endothelial cells induce lesions with the histopathologic features of ks. we have now cloned by limiting dilution seven morpholo ... | 1993 | 8496612 |
| changing patterns of respiratory disease in hiv positive patients in a referral centre in the united kingdom between 1986-7 and 1990-1. | respiratory illness is a significant contributor to morbidity and mortality in patients with human immunodeficiency virus (hiv) infection and the acquired immunodeficiency syndrome (aids). it has been suggested that pneumocystis carinii pneumonia is no longer the most frequent cause of respiratory disease in this group because of widespread use of prophylaxis and anti-retroviral drugs. | 1993 | 8497816 |
| visceral myogenic tumors. a manifestation of hiv infection in children. | we report a primary smooth-muscle tumor of undetermined malignant potential of the liver in a child with acquired immune deficiency syndrome (aids). this patient represents the eighth child infected with the human immunodeficiency virus who developed a mesenchymal tumor other than kaposi's sarcoma. all these children were younger than 10 years of age. these tumors often were histologically or clinically malignant and all but one were smooth-muscle tumors. these tumors arose exclusively in viscer ... | 1993 | 8214263 |
| systemic expression of hiv-1 tat gene in transgenic mice induces endothelial proliferation and tumors of different histotypes. | the human immunodeficiency virus tat protein, a transactivator of viral and cellular genes, is suspected to be involved in the pathogenesis of acquired immunodeficiency syndrome-associated tumors. we report that transgenic mice carrying a recombinant dna containing bk virus early region and the human immunodeficiency virus tat gene develop skin leiomyosarcomas, squamous cell papillomas and carcinomas, adenocarcinomas of skin adnexa, glands, and b-cell lymphomas. although the incidence of hepatoc ... | 1993 | 8221699 |
| [a role of dentists in the management of hiv-infected persons]. | oral manifestations of hiv infection include hairy leukoplakia, sjögren's syndrome-like conditions, necrotizing stomatitis, kaposi's sarcoma, and a variety of opportunistic viral or mycotic infections. the well awareness of hiv-associated oral lesions can contribute to the early detection and diagnosis of hiv infection. prevention and early treatment of common oral diseases including dental caries and periodontal disease, which may evolve into necrotizing gingivitis and stomatitis under immunode ... | 1993 | 8225170 |
| classification and diagnostic criteria for oral lesions in hiv infection. ec-clearinghouse on oral problems related to hiv infection and who collaborating centre on oral manifestations of the immunodeficiency virus. | a consensus has been reached on the classification of the oral manifestations of hiv infection and their diagnostic criteria, based on presumptive and definitive criteria. the former relate to the initial clinical appearance of the lesion and the latter are often the result of special investigations. candidiasis, hairy leukoplakia, specific forms of periodontal disease [linear gingival erythema, necrotising-(ulcerative) gingivitis and necrotising(ulcerative) periodontitis], kaposi's sarcoma and ... | 1993 | 8229864 |
| nuclear medicine and aids. | the human immunodeficiency virus (hiv) infection and its associated illnesses in a relatively young population of patients provides an expanding role for nuclear medicine. the disease enforces a review of each department's infection control procedures. it also necessitates a widening of the differential diagnosis in high risk patients. it has also resulted in an increase in the number of patients presenting with diseases such as pneumocystis carinii pneumonia, kaposi's sarcoma etc. which prior t ... | 1993 | 8233226 |
| kaposi's sarcoma mimicking cellulitis. | although kaposi's sarcoma is not the most common cause of death in aids patients, it is often one of the initial opportunistic illnesses associated with human immunodeficiency virus infection. extensive plaque formation and edema in the lower extremities may take on the appearance of cellulitis, and in dark-skinned persons, the lesions of the neoplasm may not be noticeable. treatment is palliative; therapy for local effect is appropriate unless lesions are extensive or systemic involvement is pr ... | 1993 | 8247991 |
| detection of human immunodeficiency virus type 1 and human papillomavirus type 16 in acquired immunodeficiency syndrome-related and classic kaposi's sarcoma. | 1993 | 8250588 | |
| inhibition of hiv-1 replication by daunorubicin. | members of the anthracycline family of drugs such as daunorubicin (dnr) are currently being employed in cancer therapy, treatment of kaposi's sarcoma and lymphomas in hiv-1 infected patients. these drugs may have an anti-viral activity against hiv-1. experiments conducted on u937 (a promonocytic cell line), peripheral blood monocytes (without t cells) and infected with hiv-1 showed anti-viral activity at nanogram/ml concentrations, without affecting cell proliferation and cell viability. treatme ... | 1993 | 8261687 |
| inhaled isobutyl nitrite compromises t-dependent, but not t-independent, antibody induction. | habitual abuse of nitrite inhalants has been linked in epidemiological studies with seropositivity to human immunodeficiency virus and, separately, with kaposi's sarcoma among aids patients. mice exposed to isobutyl nitrite in an inhalation chamber for 45 min/day for 14 days had depressed igm and igg antibody responses. the inhibition was dose-dependent at 750-900 ppm, but antibody responses were increased at an intermediate (600 ppm) dose. gender differences in immunotoxicity were not observed. ... | 1993 | 8262696 |
| radiation therapy in endemic (african) kaposi's sarcoma. | evaluating the role of radiation therapy in the treatment of the endemic, african variant of kaposi's sarcoma. a retrospective analysis. | 1993 | 8262845 |
| mycoplasma penetrans infection in male homosexuals with aids: high seroprevalence and association with kaposi's sarcoma. | antibodies to mycoplasma penetrans were found at an unusually high frequency in male homosexuals with aids (55 of 149; 37%) and in human immunodeficiency virus (hiv)-infected asymptomatic homosexuals (13 of 49; 26.5%) but not in intravenous drug users (3 of 308; 1%) and hemophiliacs (1 of 165; 0.6%) with or without hiv-1 infection. thus, both m. penetrans and kaposi's sarcoma (ks) occur primarily in male homosexuals and rarely in other groups of patients at high risk of aids. among 414 hiv-1-inf ... | 1993 | 8268356 |
| immune-based therapeutics: scientific rationale and the promising approaches to the treatment of the human immunodeficiency virus-infected individual. | the primary approach to therapy for infection with human immunodeficiency virus (hiv) continues to be centered around antiretroviral agents that have conferred significant clinical benefits. the considerable degree of immunologic dysfunction in hiv infection, however, has led to intense interest in methods of immune stimulation and reconstitution. immunomodulatory intervention in hiv infection is highly controversial. over the years a number of immunomodulatory agents--many with only a poor rati ... | 1993 | 8268360 |
| aids-associated kaposi's sarcoma in an indian female. | we report the first case of aids-associated kaposi's sarcoma in a 35 year old indian female, a commercial sex worker, with lesions involving skin and mucous membranes. diagnosis was confirmed on histopathology, electron microscopy, seropositivity, (elisa and western blot) as well as pepti-lav test and viral culture. antibodies to human immunodeficiency virus, both hiv-1 & 2, were present. hla dr5,7 was positive on oligotyping. genetic predisposition, therefore, may be suspected. | 1993 | 8270582 |
| pulmonary manifestations of acquired immunodeficiency syndrome-associated malignancies. | significant progress has been made in the treatment and prophylaxis of human immunodeficiency virus (hiv)-associated infections. as patients with hiv infection live longer, more cases with hiv-associated malignancies are being reported. pulmonary complications of hiv-associated kaposi's sarcoma and non-hodgkin's lymphoma present clinicians with diagnostic and therapeutic challenges. pulmonary involvement with kaposi's sarcoma ranges from 6% to 32%. pulmonary involvement with acquired immunodefic ... | 1993 | 8278681 |
| bronchoalveolar lavage phospholipid abnormalities in hiv-infected patients. | our aim was to evaluate the quality of pulmonary surfactant, a nonspecific defence system, during the course of human immunodeficiency virus) infection. protein and phospholipid composition were determined in 127 bronchoalveolar lavage (bal) fluids from 89 hiv seropositive patients (54 acquired immune deficiency syndrome (aids), 35 non-aids) and 11 healthy controls. in all of the hiv bal samples, biochemical abnormalities were found. in subjects with pulmonary infection or kaposi's sarcoma, the ... | 1993 | 8287946 |
| [predictive value of the assay of serum anti-p25 antibodies in patients with human immunodeficiency virus (hiv-1) infection]. | to assess whether monitoring of antibodies (ab) directed against the hiv-1 p25 core protein may be used as a predictive marker in the biological monitoring of hiv-infected patients, a study was performed on a transversal cohort of 68 cdc stage ii-iii, and 36 arc and 26 aids stage iv patients, 37 of whom were being treated with anti-retroviral therapy. a second cohort included 56 patients followed for 3-7 years: 15 stage ii-iii, 11 arc and 30 aids patients (opportunistic infections: 14; kaposi's ... | 1993 | 8291842 |
| histopathology of human immunodeficiency virus-associated esophageal disease. | we evaluated the histopathologic features of the esophageal mucosa in 88 patients seropositive for human immunodeficiency virus (hiv). all patients had an upper endoscopy because of esophageal symptoms. forceps biopsies and brushings of the esophagus were examined histologically and cytologically for evidence of viral, fungal, and mycobacterial infections: in addition, biopsies and brushings were cultured for cytomegalovirus and herpes simplex. esophageal inflammation (acute or chronic) was grad ... | 1993 | 8204115 |
| aids and the gateway of the body. | in the early phases of hiv infection, the oral cavity may develop erythematous and pseudomembranous candidiasis, oral hairy leukoplakia (ohl), necrotizing ulcerative periodontal disease, kaposi's sarcoma, and infections with herpes simplex viruses, cytomegalovirus, epstein-barr virus, and varicella zoster virus. the leading oral infections are candidiasis and ohl. the most common oral form of candidiasis is pseudomembranous, which appears white and milky and can be easily removed from the mucosa ... | 1994 | 8207272 |
| [cardiac tamponade and kaposi's sarcoma]. | the case of a 31 year-old intravenous drug addict female patient with infection by the human immunodeficiency virus who had recurrent cardiac tamponade and who was diagnosed by pericardic biopsy as kaposi's sarcoma is reported. the patient demonstrated involvement by cutaneous, mucosal, lymph node and probably pleuropulmonary kaposi's sarcoma. thoracic radiography, computerized tomography and echocardiography only showed the presence of pericardic effusion. neither did the pericardic fluid obtai ... | 1994 | 8208010 |
| pentoxifylline and meclofenamic acid treatment reduces clinical manifestations in a murine model of aids. | c57/bl/6 mice infected with lp-bm5 mulv virus developed an aids-like disease (maids) with splenomegaly, leukopenia, thrombocytopenia, anemia, decreased numbers of helper/inducer and suppressor/cytotoxic t-cells and decreased production of interferon alpha. we have shown previously that hiv-associated kaposi's sarcoma tissue contains high levels of prostaglandin e2 (pge2), and this inhibits interferon synthesis through a camp-dependent second-messenger process. in this study we treated groups of ... | 1994 | 8301544 |
| gastrointestinal manifestations of aids in children. | the gastrointestinal manifestations of aids in children are related to opportunistic infections, lymphoproliferative disease, and cancer. the infections that affect the gastrointestinal tract at different sites also occur in patients without aids. however, in children with aids, the infections are more severe, often relapse, and are harder to eradicate. candidiasis is the most common infection in the esophagus, but infections caused by herpes simplex virus and cytomegalovirus also are common. ra ... | 1994 | 8310932 |
| retrovirus-mediated transfer and long-term expression of hiv type 1 tat gene in murine hematopoietic tissues. | replication of the human immunodeficiency virus (hiv) is regulated tightly by the tat and rev genes. the tat gene of hiv is a potent trans-activator of virus gene expression. trans-activation is mediated through the tat-responsive element (tar). tat also has been shown to affect transcription of cellular genes and to trans-activate other viral promoters. in transgenic animals, tat expression in skin was implicated in the development of lesions resembling kaposi's sarcoma (ks). more recently, evi ... | 1994 | 7888206 |
| cultured aids-related kaposi's sarcoma cells retain a proliferative bioenergetic profile but demonstrate reduced cytoprotective capabilities. | features of aids-related kaposi's sarcoma (aids-ks), such as the multifocal presentation at mucosal and epidermal sites subjected to trauma, suggest that aids-ks is initially a reactive hyperplasia that subsequently progresses to a neoplasia. it is recognized that there is an association between sustained inflammatory states and the subsequent development of neoplasia (e.g., ulcerative colitis/colonic adenocarcinoma). furthermore, patients who develop aids-ks experience both a constant immune st ... | 1994 | 7890815 |
| [detection of markers of the human t-cell leukemia virus in patients with t-cell lymphoma and kaposi's sarcoma]. | nine patients with kaposi's sarcoma and five suffering from t-cell lymphoma have been examined. antibodies to htlv-1 were not found in these patients. the primary cellular cultures were isolated from blood and lymph nodes of the patients. viral particles (type c) were found in the culture obtained from the patient with lymphoma of t-cell origin. dnas from the primary cellular cultures from patients with lymphoma or sarcoma contained the sequences homologous to gag-gene of htlv-1. the data suppos ... | 1994 | 7891727 |
| surgical treatment of cytomegalovirus enterocolitis in severe human immunodeficiency virus infection. report of eight cases. | the aim of this study was to describe our experiences of surgical removal of inflamed bowel in cytomegalovirus enterocolitis. | 1994 | 8287750 |
| persistent cytomegalovirus infection of semen increases risk of aids. | to evaluate if persistent cytomegalovirus (cmv) infection of semen in human immunodeficiency virus type 1 (hiv-1) antibody-positive men increases aids risk, serial cultures for cmv every 3-6 months were attempted four or more times from 164 men followed 3 years. cmv was never isolated from 58 men, in 1 or 2 samples from 54 (intermittently positive), and in > or = 3 samples from 52 (persistently positive). the cox model was used to estimate relative hazards while controlling for cd4 cell number. ... | 1994 | 8133089 |
| aids-related kaposi's sarcoma: a review. | infection with the human immunodeficiency virus (hiv) is the primary cause of aids and related disorders. infection with hiv results in diminished cellular immunity, propensity to opportunistic infections, and an increased incidence of certain neoplasms. kaposi's sarcoma (ks) is the most common neoplasm in persons infected with hiv. this epidemic, or hiv-related ks, usually follows an aggressive course with involvement of skin, lymph nodes, and internal organs. normally, the disease has a progre ... | 1994 | 8175336 |
| recognizing skin lesions of systemic fungal infections in patients with aids. | mucocutaneous lesions may be the initial feature or a subsequent manifestation of disseminated systemic fungal infections in patients who are seropositive for human immunodeficiency virus (hiv). these lesions can be classified by their morphologic appearance as macules, nodules, papules, patches, plaques, pustules or ulcers. some lesions mimic the morphology of conditions such as herpes simplex, kaposi's sarcoma and molluscum contagiosum, or present as abscesses, fistulas or purpura. since the m ... | 1994 | 8184797 |