Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| detection of common dermatophytes in clinical specimens using a simple quantitative real-time taqman polymerase chain reaction assay. | dermatophytes are common fungal pathogens causing mostly superficial infections in humans with a high prevalence worldwide. traditional detection techniques are time-consuming and insensitive, whereas molecular detection methods have proved to be much more rapid and sensitive. | 2016 | 26406273 |
| molecular characterization and in vitro antifungal susceptibility of 316 clinical isolates of dermatophytes in iran. | dermatophytosis is a common mycotic infection of the skin, nail, and hair, associated with major public health concern worldwide. various species of dermatophytes show significant differences in susceptibility to antifungals. here, we present the antifungal susceptibility of a large collection of molecularly identified dermatophyte isolates obtained from tropical region of south of iran. a total of 9485 patients clinically suspected to have cutaneous fungal infections were examined. dermatophyto ... | 2016 | 26369643 |
| species identification of dermatophytes in paraffin-embedded biopsies with a new polymerase chain reaction assay targeting the internal transcribed spacer 2 region and comparison with histopathological features. | dermatophytosis is a very common skin infection with a broad clinical spectrum. biopsies are often used to confirm the diagnosis, especially when the clinical presentation is unusual. not uncommonly, organisms are hard to find even with periodic acid-schiff stains. polymerase chain reaction (pcr) for dermatophytes can be used in such cases. | 2016 | 26556042 |
| epidemiology of dermatophytoses in crete, greece. | dermatophytoses are among the most frequently diagnosed skin infections worldwide. however, the distribution of pathogenic species and the predominating anatomical sites of infection vary with geographical location and change over time. the aim of this study was to determine the epidemiological and aetiological factors of dermatophytoses in crete, greece over the last 5-year period (2011-2015) and their incidence in relation to the gender and the age of the patients. we compared our findings wit ... | 2016 | 27904054 |
| antidermatophytic action of resorcinol derivatives: ultrastructural evidence of the activity of phenylethyl resorcinol against microsporum gypseum. | in this work, we evaluated the antidermatophytic activities of three resorcinol derivatives that have a history of use in dermo-cosmetic applications to discover molecules with multiple dermatological activities (i.e., multi-target drugs), thereby reducing the cost and time necessary for new drug development. the antidermatophytic activities of the three skin lighteners were evaluated relative to the known antifungal drug fluconazole on nine dermatophytes responsible for the most common dermatom ... | 2016 | 27706019 |
| econazole nitrate foam 1% improves the itch of tinea pedis. | econazole nitrate topical foam, 1%, is indicated for the treatment of interdigital tinea pedis caused by <em>trichophyton rubrum, trichophyton mentagrophytes,</em> and <em>epidermophyton floccosum</em> in patients 12 years of age and older. the symptom of itch or pruritus was evaluated in two randomized, double-blind, parallel-group, vehicle-controlled, multicenter phase iii studies in which econazole foam was compared with foam vehicle in subjects with interdigital tinea pedis. a thin, uniform ... | 2016 | 27602974 |
| epidemiological trends of dermatophytosis in tehran, iran: a five-year retrospective study. | dermatophytosis is the most frequent fungal infection all over the world and its frequency is constantly increasing. the aim of this study was to evaluate clinical features and epidemiological trends of dermatophytosis over the years 2010 to 2014 in tehran, iran. | 2016 | 27520535 |
| characterization of clinically important dermatophytes in north of iran using pcr-rflp on its region. | dermatophytosis is considered as one of the major public health problems in the world. accurate identification of the dermatophytes species is important for recognition of the environment and animal sources of infection. in this survey, 1500 clinical specimens taken from outpatients suspected of dermatophytosis and they were examined by direct microscopy and culture. | 2016 | 27496524 |
| antidermatophytic activity of ethanolic extract from croton tiglium. | dermatophytosis, which is caused mainly by genera of trichophyton, epidermophyton, and microsporum, is a frequent dermatological problem in tropical and subtropical countries. investigations were carried out in this study to evaluate the antidermatophytic activity of the stems, leaves, and seeds of croton tiglium, one of the traditional medicine plants indigenous to asia. ethanolic extracts of the stems, leaves, and seeds of c. tiglium were prepared by cold soak or heat reflux methods. the antid ... | 2016 | 27446946 |
| molecular identification and phylogenetical analysis of dermatophyte fungi from latin america. | dermatophytes constitute a complex group of fungi, comprised of by the genera trichophyton, epidermophyton and microsporum. they have the ability to degrade keratin and cause human and animal infections. molecular techniques have made their identification faster and more accurate, and allowed important advances in phylogenetic studies. we aim to identify molecularly and to determine the phylogenetic relationships in dermatophyte fungi from brazil and other latin american countries, using dna seq ... | 2016 | 27432316 |
| evaluation of incubation time for dermatophytes cultures. | in general, it is recommended to incubate dermatophytes cultures for a minimum of 4 weeks. several aspects of routine fungal cultures should be evaluated in order to implement appropriate and necessary changes. the aim of this study was to determine the optimum incubation time for routine dermatophytes cultures, analysing the time to find first fungal growth by visual observation. we recorded the time when the initial growth was detected for all dermatophyte isolates during a 4-year period. a to ... | 2016 | 27144472 |
| antifungal susceptibility and virulence factors of clinically isolated dermatophytes in tehran, iran. | dermatophytes possess a wide array of virulence factors and various antifungal susceptibility patterns which influence their pathogenesis in humans and animals. the aim of this study was to evaluate antifungal susceptibility and keratinase and proteinase activity of 49 dermatophyte strains from the genera microsporum, trichophyton and epidermophyton which were isolated from human cases of dermatophytosis. | 2016 | 27092223 |
| epidemiological aspects of dermatophytosis in khuzestan, southwestern iran, an update. | dermatophytosis is among the most common superficial mycoses in iran. the purpose of this report was to update the clinical and mycological features of human dermatophytosis in the khuzestan, southwestern iran. in the framework of a one-year survey, a total of 4120 skin, hair and nail samples obtained from the outpatients with symptoms suggestive of tinea were analyzed by using direct microscopy, culture and molecular identification methods. strains isolated from cultures were subjected to ampli ... | 2016 | 26886443 |
| phylogenetic analysis of dermatophyte species using dna sequence polymorphism in calmodulin gene. | use of phylogenetic species concepts based on rdna internal transcribe spacer (its) regions have improved the taxonomy of dermatophyte species; however, confirmation and refinement using other genes are needed. since the calmodulin gene has not been systematically used in dermatophyte taxonomy, we evaluated its intra- and interspecies sequence variation as well as its application in identification, phylogenetic analysis, and taxonomy of 202 strains of 29 dermatophyte species. a set of primers wa ... | 2016 | 26868901 |
| multilaboratory evaluation of in vitro antifungal susceptibility testing of dermatophytes for me1111. | me1111 is a novel small molecule antifungal agent under development for the topical treatment of onychomycosis. standardization of the susceptibility testing method for this candidate antifungal is needed. toward this end, 8 independent laboratories determined the interlaboratory reproducibility of me1111 susceptibility testing. in addition, we subsequently identified 2 strains as quality control (qc) isolates for the method. in the reproducibility study, 5 blinded clinical strains each of trich ... | 2016 | 26719434 |
| a 10-year study of dermatophytoses in isfahan, iran. | dermatophyte infections are very common worldwide and their epidemiological characteristics vary according to the geographical region and have altered in the last decades. the aim of the present investigation was to determine the diversity of causative agents of dermatophytoses and describe the epidemiological condition of infection in isfahan, iran, between 2003 and 2012. specimens were collected from hair, nail, and skin and were examined by conventional methods such as direct microscopy, cult ... | 2016 | 25902908 |
| preparation and physicochemical characterization of topical chitosan-based film containing griseofulvin-loaded liposomes. | griseofulvin is an antifungal drug and is available as oral dosage forms. development of topical treatment could be advantageous for superficial fungal infections of the skin. in this study, films prepared from the incorporation of griseofulvin-loaded liposomes in chitosan film for topical drug delivery in superficial fungal infections. the properties of the films were characterized regarding mechanical properties, swelling, ability to transmit vapor, drug release, thermal behavior, and antifung ... | 2017 | 27429928 |
| toward a novel multilocus phylogenetic taxonomy for the dermatophytes. | type and reference strains of members of the onygenalean family arthrodermataceae have been sequenced for rdna its and partial lsu, the ribosomal 60s protein, and fragments of β-tubulin and translation elongation factor 3. the resulting phylogenetic trees showed a large degree of correspondence, and topologies matched those of earlier published phylogenies demonstrating that the phylogenetic representation of dermatophytes and dermatophyte-like fungi has reached an acceptable level of stability. ... | 2017 | 27783317 |
| the changing face of dermatophytic infections worldwide. | dermatophytes evolve along with the geography and socioeconomic conditions. epidermophyton floccosum, microsporum audouinii and trichophyton schoenleinii acted as the major pathogens of superficial fungal diseases 100 years ago, but their frequency decreased dramatically since the middle of the twentieth century and they are limited to some less-developed countries nowadays; meanwhile, frequency of trichophyton rubrum, trichophyton interdigitale, trichophyton tonsurans and microsporum canis incr ... | 2017 | 27783316 |
| inhibition of dermatophytes by photodynamic treatment with curcumin. | treatment of dermatophytoses with currently available antimycotic agents is often tedious and sometimes unsatisfactory. a search for better therapeutic methods-ideally with an immediate fungicidal effect-has, among others, lead to photodynamic procedures as a promising alternative, and recently curcumin was found to be a suitable agent for this application. in this study the effect of photodynamic treatment with curcumin on dermatophytes was tested in vitro wells of microtiter plates were filled ... | 2017 | 28053148 |
| chemical characterisation and biological activity of leaf essential oils obtained from pistacia terebinthus growing wild in tunisia and sardinia island. | in the present work the chemical compositions, measured by gc and gc-ms, of the essential oils obtained by hydrodistillation from leaves of pistacia terebinthus collected in bizerte (tunisia) and baunei (italy) are reported. both essential oils possessed high content of monoterpene hydrocarbons (86.3% and 90.9%, respectively), being α-pinene (62.4 vs. 35.0)%, camphene (3.0 vs. 2.4)%, β-pinene (12.1 vs. 4.5)%, terpinolene (1.7 vs. 35.2)% and β-phellandrene (3.8 vs. 4.5)% the main components. the ... | 2017 | 28278668 |
| enzymatic and non-enzymatic virulence activities of dermatophytes on solid media. | dermatophytes are keratinophilic fungi causing superficial cutaneous infections that account 20-25% of the global population. as per literature search, there is a dearth in the study on virulence factors of dermatophytes from the indian sub-continent and moreover the association of the virulence factors and the host tissue in vitro helps in understanding the host-pathogen interaction. | 2017 | 28384862 |
| antidermatophytic and protease-inhibiting activities of zerumbone: a natural sesquiterpene from the rhizome of zingiber zerumbet (l.) roscoe ex j.e; smith. | due to increase in the number of patients with impaired immunity, incidence of dermatophytoses has increased considerably. antidermatophytic agents with anti-inflammatory and protease-inhibiting activities will help in restricting inflammatory response associated with dermatophytoses. | 2017 | 28216875 |
| antifungal activity of lactobacillus against microsporum canis, microsporum gypseum and epidermophyton floccosum. | a total of 220 lactic acid bacteria isolates were screened for antifungal activity using aspergillus fumigatus and aspergillus niger as the target strains. four lactobacillus strains exhibited strong inhibitory activity on agar surfaces. all four were also identified as having strong inhibitory activity against the human pathogenic fungi microsporum canis, microsporum gypseum and epidermophyton floccosum. one of the four lactobacilli, namely lb. reuteri ee1p exhibited the most inhibition against ... | 2017 | 22539027 |
| nimesulide inhibits pathogenic fungi: pge2-dependent mechanisms. | certain non-steroidal anti-inflammatory drugs can inhibit fungal growth, fungal prostaglandin e2 production, and enzyme activation. this study aims to investigate the antifungal effect of nimesulide against pathogenic filamentous fungi and yeast. the experiments detailed below were also designed to investigate whether the action is dependent on e2 fungal prostaglandins. our data showed that nimesulide exhibited potent antifungal activity, mainly against trichophyton mentagrophytes (atcc 9533) an ... | 2017 | 27866353 |
| anti-dermatophyte activity of leguminosae plants from southern brazil with emphasis on mimosa pigra (leguminosae). | intensive prophylactic use of antifungals leads to the increase of drug resistance and the need for new and more effective treatments are real. plants from leguminosae family are rich in flavonoids, for which numerous biological activities have been described, including antifungal effects. | 2017 | 28822705 |
| distribution of species of dermatophyte among patients at a dermatology centre of nghean province, vietnam, 2015-2016. | vietnam is a tropical country so fungal diseases including dermatophytosis may be prevalent, but epidemiological profiles of agents responsible for the infection have rarely been reported. | 2017 | 28831770 |
| diagnosis of dermatophytosis by conventional methods and comparatative analysis of sabouraud dextrose agar and dermatophyte test medium for isolation of dermatophytes. | dermatophytosis is a fungal disease which ranked as one of the most common cutaneous condition in all over the world. the aim of this cross sectional observational study is to identify the etiological agent of dermatophytosis and comparison of sabouraud dextrose agar (sda) and dermatophyte test medium (dtm) for the primary isolation of dermatophytes among the clinically suspected cases of dermatophytosis from the outpatient department of dermatology and venereology, mymensingh medical college ho ... | 2017 | 28588164 |
| dermatophytosis of the scrotum, penis and lip. | a young male had tinea cruris due to epidermophyton floccosum. he had associated dermatophytosis of the scrotum, penis and upper lip from which the same species of fungus was isolated. on the lip, the lesion extended to the vermilion area (prolabium) of the lip and the term 'tinea labialis' is suggested for this condition. | 2017 | 28145332 |
| clinico mycological study of dermatophytosis in a coastal area. | clinico-mycological features of one hundred patients suffering from tinea cruris are reported. ninety two per cent are males and 79% are in the age group of 11-39 years. involvement of axillae is seen in four penile involvement in five patients. 'twenty-eight patients have tinea corporis and nine tinea vesicolor also. seventy seven patients show isolation of dernm-tophytes by culture. the commonest species of dermatophytes is trichophyron rubrum (57.1%) followed by t. mentagraphytes (31.20/o), e ... | 2017 | 28176711 |
| mycology of cutaneous fungal infections in ambajogai: a rural area. | two hundred and eithteen cases of fungal skin infections were studied. tinea cruris was most common (34.4%), followed by tinea corporis (23.8%) znd tinea pedis (21.6%). tinea versicolor (8.7%) tinea manum (4.6%) tinea ungaium (3.7%) and tinea capitis (3.2%) were also seen. the male: female ratio was 4:1. the total isolates were 117. trichophyton rubrum was the most common isolate (35%). closely followed by epidermophyton floccosum (31.6%). trichphyton mentagrophytes (17.9%), malassezia furfur (1 ... | 2017 | 28211405 |