Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| minocycline hcl microspheres reduce red-complex bacteria in periodontal disease therapy. | the objective of this trial was to measure the antimicrobial effects of a minocycline hcl microsphere (mm) local drug-delivery system when used as an adjunct to scaling and root planing (srp). dna probe analysis for 40 bacteria was used to evaluate the oral bacteria of 127 subjects with moderate to advanced chronic periodontitis. | 2007 | 17668977 |
| diagnosis and anti-infective therapy of periodontitis. | periodontal diseases (gingivitis and periodontitis) are chronic bacterial infections with a remarkably high prevalence and morbidity. periodontitis, in contrast to gingivitis, is not reversible, is associated with certain bacterial species and affects all of the soft tissue and bone that support teeth. among the periodontal pathogens, species, such as aggregatibacter (actinobacillus) actinomycetemcomitans, porphyromonas gingivalis, prevotella intermedia, tannerella forsythensis, and several form ... | 2007 | 17678431 |
| microbiologic analysis of periodontal pockets and carotid atheromatous plaques in advanced chronic periodontitis patients. | in recent years, many researchers have focused their attention on the ability of periodontal pathogens to colonize atheromatous plaques. nevertheless, a clear correlation between the detection rates of periodontopathic bacterial dna in atheromas and in subgingival plaque samples has not been established. the aim of our study was to assess the presence of five periodontal pathogens (actinobacillus actinomycetemcomitans, prevotella intermedia, porphyromonas gingivalis, treponema denticola, and tan ... | 2007 | 17760541 |
| periodontopathic microorganisms in peripheric blood after scaling and root planing. | the objective of this study was to evaluate the frequency of periodontopathic and other subgingival anaerobic and facultative bacteria in the bloodstream following scaling and root planing (srp). | 2007 | 17850606 |
| identification of tannerella forsythia antigens specifically expressed in patients with periodontal disease. | molecular pathogenesis of tannerella forsythia, a putative periodontal pathogen, has not yet been adequately elucidated due to limited information on its virulence factors. here, identification of in vivo expressed antigens of t. forsythia is reported using in vivo-induced antigen technology (iviat). among 13 000 recombinant clones screened, 16 positive clones were identified that reacted reproducibly with sera obtained from patients with periodontal disease. dna sequences from 12 of these in vi ... | 2007 | 17868359 |
| [pathogenic potential of porphyromonas gingivalis, treponema denticola and tannerella forsythia, the red bacterial complex associated with periodontitis]. | periodontitis are mixed bacterial infections leading to destruction of tooth-supporting tissues, including periodontal ligament and alveolar bone. among over 500 bacterial species living in the oral cavity, a bacterial complex named "red complex" and made of porphyromonas gingivalis, treponema denticola and tannerella forsythia has been strongly related to advanced periodontal lesions. while periodontopathogenic bacteria are the primary etiologic factor of periodontitis, tissue destruction essen ... | 2007 | 17049750 |
| two subgingival plaque-sampling strategies used with rna probes. | the purpose of this study was to compare the results of microbiological rna-probe analysis after subgingival plaque sampling applying two different strategies. | 2007 | 17199542 |
| comparison of subgingival bacterial sampling with oral lavage for detection and quantification of periodontal pathogens by real-time polymerase chain reaction. | saliva has been studied for the presence of subgingival pathogens in periodontitis patients. with the anaerobic culture technique, the discrepancy between salivary recovery and subgingival presence has been significant, which makes this approach not suitable for practical use in the microbial diagnosis of periodontitis patients. the real-time polymerase chain reaction (pcr) technique represents a very sensitive technique to detect and quantify bacterial pathogens. the aim of the study was to com ... | 2007 | 17199543 |
| clinical and microbiological profiles of human immunodeficiency virus (hiv)-seropositive brazilians undergoing highly active antiretroviral therapy and hiv-seronegative brazilians with chronic periodontitis. | this study compares the periodontal clinical profile and the composition of the subgingival microbiota of human immunodeficiency virus (hiv)-seropositive and hiv-seronegative subjects with chronic periodontitis. | 2007 | 17199544 |
| phylogenetic analysis of bacterial and archaeal species in symptomatic and asymptomatic endodontic infections. | phylogenetic analysis of bacterial and archaeal 16s rrna was used to examine polymicrobial communities within infected root canals of 20 symptomatic and 14 asymptomatic patients. nucleotide sequences from approximately 750 clones amplified from each patient group with universal bacterial primers were matched to the ribosomal database project ii database. phylotypes from 37 genera representing actinobacteria, bacteroidetes, firmicutes, fusobacteria and proteobacteria were identified. results were ... | 2007 | 17172525 |
| molecular analysis of the subgingival microbiota in health and disease. | this investigation provides molecular analyses of the periodontal microbiota in health and disease. subgingival samples from 47 volunteers with healthy gingivae or clinically diagnosed chronic periodontitis were characterized by pcr-denaturing gradient gel electrophoresis (dgge) with primers specific for the v2-v3 region of the eubacterial 16s rrna gene. a hierarchical dendrogram was constructed from band patterns. all unique pcr amplicons (dgge bands) were sequenced for identity. samples were a ... | 2007 | 17085691 |
| high incidence of actinobacillus actinomycetemcomitans infection in acute coronary syndrome. | recent epidemiological studies suggest that periodontitis is an important risk factor for coronary heart disease (chd). the aim of this study was to evaluate the association between periodontitis and chd, particularly acute coronary syndrome (acs), focusing on microbiological and immunological features. twenty-eight chd patients, 15 with acs and 13 with chronic chd, were included in this study. coronary angiography, periodontal examination, and dental radiography were performed in all patients. ... | 2007 | 18160759 |
| clinical characteristics and microbiota of progressing slight chronic periodontitis in adults. | this study sought clinical and microbial risk indicators for progressing slight periodontitis. | 2007 | 17877747 |
| benefits of additional courses of systemic azithromycin in periodontal disease case report. | the strong association of subgingival anaerobic bacteria, such as porphyromonas gingivalis, treponema denticola and tannerella forsythia, with destructive periodontal disease has been well documented in the literature. several double-blind studies have also shown the beneficial use of systemic antimicrobials that are active against these microorganisms in conjunction with conventional periodontal treatment, especially when periodontal abscesses and/or suppuration upon probing are present. four c ... | 2007 | 17891880 |
| implant surface analysis and microbiologic evaluation of failed implants retrieved from smokers. | the aim of this study was to evaluate the microbiota and surface of failed titanium dental implants from 4 manufacturers. twelve mobile dental implants were retrieved from 10 smokers after 3 to 10 years of functional loading. before implant removal, microbial samples were taken and evaluated using polymerase chain reaction. after implant removal, analyses of the failed implant surfaces were performed using scanning electron microscopy and energy-dispersive spectrometer x-ray. periodontal pathoge ... | 2007 | 17912965 |
| polymerase chain reaction of porphyromonas gingivalis, treponema denticola, and tannerella forsythia in primary endodontic infections. | the aim of this study was to investigate the correlation between endodontic clinical signs and symptoms and the presence of porphyromonas gingivalis, treponema denticola, and tannerella forsythia or their association by nested polymerase chain reaction assay. microbial samples were taken from 50 cases with necrotic pulp tissues in primary infections. dna was extracted from the samples, which were analyzed for the presence of three endodontic pathogens by using species-specific primers. p gingiva ... | 2007 | 17931930 |
| bacterial examination of endodontic infections by clonal analysis in concert with denaturing high-performance liquid chromatography. | the aim of this study was to examine the diversity of bacterial species in the infected root canals of teeth associated with endodontic abscesses by cloning and sequencing techniques in concert with denaturing high-performance liquid chromatography. | 2007 | 17949344 |
| prevalence of fima genotypes of porphyromonas gingivalis and periodontal health status in chinese adults. | porphyromonas gingivalis fimbriae play a key role in colonization of the oral cavity. the fima gene, which encodes fimbrillin (fima), can be classified into six types (i-v and ib) according to nucleotide sequence. in the present study, we investigated the relationship between the prevalence of p. gingivalis-specific fima genotypes and periodontal health status in chinese adults. | 2007 | 17956463 |
| microbiologic changes following administration of locally delivered doxycycline in smokers: a 15-month follow-up. | additional clinical benefits have been reported with the use of locally delivered antimicrobials in the treatment of smokers; however, long-term changes in the subgingival microbiota following the use of these drugs in smokers have not been documented. the aim of this study was to evaluate long-term microbiologic changes following locally delivered doxycycline in the treatment of smokers. | 2007 | 17970681 |
| uncultivated tannerella bu045 and bu063 are slim segmented filamentous rods of high prevalence but low abundance in inflammatory disease-associated dental plaques. | uncultivated clones bu045 and bu063 and tannerella forsythia, a 'consensus periodontal pathogen', are the closest known relatives within the genus tannerella. they have been described to inhabit different ecological niches of the human oral cavity. in this study, fluorescent in situ hybridization (fish) and immunofluorescence were combined to investigate the prevalence and abundance of bu045 and bu063 in comparison to t. forsythia in plaques from gingivitis, necrotizing ulcerative gingivitis (nu ... | 2007 | 17975090 |
| [quantification of tannerella forsythensis in chronic periodontitis patients]. | to compare the number of the tannerella forsythensis (t. forsythensis), total bacteria, and proportion of t. forsythensis in subgingival specimens in diseased sites of chronic periodontitis patients and in healthy sites of periodontally healthy subjects, and clarify the relationship between bacterial load and periodontal status. | 2007 | 18072558 |
| prevalence of porphyromonas gingivalis and bacteroides forsythus in chronic periodontitis by multiplex pcr. | the present research decided to study prevalence of porphyromonas gingivalis and bacteroides forsythus in chronic periodontitis patient by use of multiplex pcr. the subgingival plaque samples from 61 patients suffering from chronic periodontitis with probing depth pd > or = 6 and 40 healthy controls were collected by sterile curette. in this study we used two species-specific forward primers in combination with a single reverse primer. these primers target variable and conserved region of 16s rr ... | 2007 | 19090291 |
| bacterial markers of periodontal diseases and their practical significance in dentistry. | the incidence and prevalence of actinobacillus actinomycetemcomitans, porphyronmonas gingivalis, and tannerella forsythensis in specimens of subgingival dental deposit were evaluated in 495 residents of st. petersburg aged 6-82 years. the microorganisms were detected by gene-specific pcr of 16s rdna. in accordance with age-specific increase in the incidence of gingival diseases, the percentage of samples containing t. forsythensis and p. gingivalis was significantly higher in adult and elderly p ... | 2007 | 18642710 |
| periodontal debridement as a therapeutic approach for severe chronic periodontitis: a clinical, microbiological and immunological study. | to clinically, microbiologically and immunologically characterize periodontal debridement as a therapeutic approach for severe chronic periodontitis. | 2008 | 18647203 |
| [identification of periodontopathogen microorganisms by pcr technique]. | periodontitis is an inflammatory disease of the supporting tissues of teeth and is a major cause of tooth loss in adults. the onset and progression of periodontal disease is attributed to the presence of elevated levels of a consortium of pathogenic bacteria. gram negative bacteria, mainly strict anaerobes, play the major role. | 2008 | 19069337 |
| [detection of periodontal pathogenic bacteria dna in coronary atheromatous plaques from patients underwent coronary artery bypass graft]. | the aim of this study was to observe the coexistence of periodontal bacteria dna (actinobacillus actinomycetemcomitans, fusobacterium nucleatum, porphyromonas gingivalis, prevotella intermedia, tannerella. forsythensis) in coronary atheromatous plaques and subgingival plaques in patients scheduled for coronary artery bypass graft. | 2008 | 19099976 |
| composition of supra- and subgingival biofilm of subjects with healthy and diseased implants. | the purpose of this study was to compare the microbial composition of supra- and subgingival biofilm in subjects with and without peri-implantitis. | 2008 | 18828812 |
| periodontal bacterial profiles in pregnant women: response to treatment and associations with birth outcomes in the obstetrics and periodontal therapy (opt) study. | a recent clinical trial (obstetrics and periodontal therapy [opt] study) demonstrated that periodontal therapy during pregnancy improved periodontal outcomes but failed to impact preterm birth. the present study evaluated seven target bacteria, aggregatibacter actinomycetemcomitans (previously actinobacillus actinomycetemcomitans), porphyromonas gingivalis, treponema denticola, tannerella forsythia (previously t. forsythensis), prevotella intermedia, campylobacter rectus, and fusobacterium nucle ... | 2008 | 18834241 |
| correlates of periodontal decline and biologic markers in older adults. | there is limited information on infectious and host responses distinguishing older people with or without active periodontitis. this study measured bacterial and serum cytokine and high-sensitivity c-reactive protein (hscrp) levels in older persons. | 2008 | 18834247 |
| detection of periodontal pathogens in oral mucous membranes of edentulous individuals. | the purpose of this study was to investigate the colonization of campylobacter rectus, porphyromonas gingivalis, aggregatibacter actinomycetemcomitans (previously actinobacillus actinomycetemcomitans), prevotella intermedia, and tannerella forsythia (previously t. forsythensis) in the tongue and cheek of newborns and elderly individuals with no teeth. | 2008 | 18834252 |
| influence of the menstrual cycle on the oral microbial flora in women: a case-control study including men as control subjects. | changes in the levels of female sex hormones during the menstrual cycle may cause cyclic differences in subgingival bacterial colonization patterns. the purpose of the present study was to test the hypothesis that hormonal changes in the menstrual cycle cause changes in the oral microbiota. | 2008 | 18834253 |
| periodontal and microbiologic evaluation of 2 methods of archwire ligation: ligature wires and elastomeric rings. | prophylactic programs to prevent dental biofilm accumulation must be implemented to minimize the risk for periodontal diseases in orthodontic patients. therefore, we assessed the possible periodontal and microbiologic changes resulting from the use of 2 methods of orthodontic archwire ligation: elastomeric rings and steel ligatures. | 2008 | 18929268 |
| immunocytochemical approach for surface layer proteins of freeze-substituted tannerella forsythensis by energy-filtering transmission electron microscopy. | tannerella forsythensis (bacteroides forsythus), an anaerobic gram-negative potential periodontal pathogens in the progression of periodontitis. it forsythensis has unique bacterial protein profiles containing major proteins with apparent molecular weight of more than 200-kda shown by sodium dodecylsulfate-polyacrylamide gel electrophoresis. it is also known to have a typical surface layer (s-layer) consisting of regularly arrayed subunits outside the outer membrane revealed by electron microsco ... | 2008 | 18975614 |
| free soluble receptor activator of nuclear factor-kappab ligand in gingival crevicular fluid correlates with distinct pathogens in periodontitis patients. | the aim of the experiment was to investigate the levels of free soluble receptor activator of nuclear factor-kb ligand (srankl) in periodontal health and disease and their correlations to clinical parameters and important periodontal pathogens. | 2008 | 18988315 |
| [relationship of putative periodontopathogenic bacteria and drug-induced gingival overgrowth]. | to investigate the effect of putative periodontopathogenic bacteria on the development of drug-induced gingival overgrowth (go) in renal transplant recipients. | 2008 | 19031785 |
| similarities in the subgingival microbiota assessed by a curet sampling method at sites with chronic periodontitis. | the goal of this study was to determine whether site-specific differences in the subgingival microbiota could be detected by the checkerboard method in subjects with periodontitis. | 2008 | 19053919 |
| persistence of extracrevicular bacterial reservoirs after treatment of aggressive periodontitis. | the purpose of this study was to test the hypothesis that periodontal pathogens associated with aggressive periodontitis persist in extracrevicular locations following scaling and root planing, systemic antibiotics, and antimicrobial rinses. | 2008 | 19053921 |
| detection of herpesviruses and periodontal pathogens in subgingival plaque of patients with chronic periodontitis, generalized aggressive periodontitis, or gingivitis. | herpesviruses may be related to the etiology of aggressive periodontitis (agp) and chronic periodontitis (cp) by triggering periodontal destruction or by increasing the risk for bacterial infection. this case-control study evaluated the presence of herpes simplex virus type i (hsv-1), epstein-barr virus type i (ebv-1), human cytomegalovirus (hcmv), aggregatibacter actinomycetemcomitans (previously actinobacillus actinomycetemcomitans), porphyromonas gingivalis, prevotella intermedia, and tannere ... | 2008 | 19053922 |
| subgingival microbial profiles in chronic periodontitis patients from chile, colombia and spain. | to investigate the subgingival microbiota of distinct periodontitis patient populations, in chile, colombia and spain, using identical clinical and bacteriological methods. | 2008 | 18081862 |
| quantitative analysis of association between herpesviruses and bacterial pathogens in periodontitis. | the development of human periodontitis may depend upon cooperative interactions among herpesviruses, specific pathogenic bacteria and tissue-destructive inflammatory mediators. this study sought to identify associations among human cytomegalovirus, epstein-barr virus and six putative periodontopathic bacteria in periodontitis lesions. | 2008 | 18086168 |
| toll-like receptor 2-mediated interleukin-8 expression in gingival epithelial cells by the tannerella forsythia leucine-rich repeat protein bspa. | tannerella forsythia is a gram-negative anaerobe strongly associated with chronic human periodontitis. this bacterium expresses a cell surface-associated and secreted protein, designated bspa, which has been recognized as an important virulence factor. the bspa protein belongs to the leucine-rich repeat (lrr) and bacterial immunoglobulin-like protein families. bspa is, moreover, a multifunctional protein which interacts with a variety of host cells, including monocytes which appear to respond to ... | 2008 | 17967853 |
| occurrence of herpes simplex virus 1 and three periodontal bacteria in patients with chronic periodontitis and necrotic pulp. | viral and bacterial associations appear to be implicated in the development of periodontal infections. little information is available describing the periodontopathic agents in root canals with necrotic pulp. in this study, the occurrence and the combinations among herpes simplex virus type 1 (hsv-1) and dialister pneumosintes, tannerella forsythia, and treponema denticola in patients with chronic periodontitis and necrotic pulp were evaluated. clinical samples from healthy subjects and patients ... | 2008 | 18389006 |
| bleeding on probing differentially relates to bacterial profiles: the oral infections and vascular disease epidemiology study. | various bacterial species are differentially prevalent in periodontal health, gingivitis or periodontitis. we tested the independent associations between three bacterial groupings and gingival inflammation in an epidemiological study. | 2008 | 18400025 |
| antibody levels to single bacteria or in combination evaluated against myocardial infarction. | evidence is accumulating that oral bacteria are associated with myocardial infarctions (mi). we were interested in studying the differences in the association between single bacteria or bacteria in combination and the relation to c-reactive protein (crp). | 2008 | 18410396 |
| microbial analysis of canals of root-filled teeth with periapical lesions using polymerase chain reaction. | the objective of the present study was to investigate the presence of nine bacterial species in root-filled teeth associated with periapical lesions using a polymerase chain reaction analysis and to correlate these species with clinical features of the cases. dna was extracted from 45 canal samples of root-filled teeth with periapical lesions. a pcr assay using species-specific primers of 16s rdna and the downstream intergenic spacer region was used for microbial detection. enterococcus faecalis ... | 2008 | 18436030 |
| a microbiological profile of symptomatic teeth with primary endodontic infections. | the aim of this study was to evaluate the composition of the microbiota of primary endodontic infections associated with symptomatic teeth. samples were collected by means of a #15 h-type file and 2 sterile paper points from 60 symptomatic (n = 30) or asymptomatic (n = 30) single-rooted teeth with necrotic pulp. the presence of 40 bacterial species was determined by the checkerboard dna-dna hybridization method. the species found in higher counts (x10(5)) in symptomatic cases were fusobacterium ... | 2008 | 18436031 |
| the prevalence of periodontopathogenic bacteria in saliva is linked to periodontal health status and oral malodour. | this study investigated whether an improvement in periodontal health resulted in changes in the prevalence of periodontopathogenic bacteria in saliva and tongue coatings and a reduction in volatile sulfur compounds (vscs: h(2)s and ch(3)sh) linked to oral malodour. the subjects were 35 patients who visited the breath odour clinic of kyushu dental college, japan. their mean age was 51.2+/-18.3 years (mean+/-sd). a clinical examination performed at baseline and 2 months after periodontal treatment ... | 2008 | 18436598 |
| comparative analysis of putative periodontopathic bacteria by multiplex polymerase chain reaction. | the polymerase chain reaction (pcr) has been applied for the rapid and specific detection of periodontopathic bacteria in subgingival plaque and is potentially of clinical benefit in the diagnosis and treatment of periodontitis subjects. however, several technical points need to be modified before the conventional pcr detection system can be used by clinicians. | 2008 | 18447853 |
| effects of age and oral disease on systemic inflammatory and immune parameters in nonhuman primates. | this report evaluated systemic inflammatory and immune biomarkers in a cohort of macaca mulatta (rhesus monkeys) maintained as a large family social unit, including an age range from <1 year to >24 years. we hypothesized that the systemic host responses would be affected by the age, gender, and clinical oral presentation of the population, each contributing to inflammatory and immune responses that would reflect chronic oral infections. the results demonstrated that the prevalence and severity o ... | 2008 | 18448617 |
| antimicrobial effectiveness of an herbal mouthrinse compared with an essential oil and a chlorhexidine mouthrinse. | the authors investigated mouthrinses' antimicrobial effectiveness against predominant oral bacteria, as determined by the minimum inhibitory concentration (mic). specifically, they evaluated an herbal mouthrinse, an essential oil rinse and a 0.12 percent chlorhexidine gluconate rinse. | 2008 | 18451378 |
| staphylococcus aureus and other bacteria in untreated periodontitis. | whether the subgingival microbiota differ between individuals with chronic and those with aggressive periodontitis, and whether smoking influences bacterial composition, is controversial. we hypothesized that the subgingival microbiota do not differ between sites in individuals with chronic or aggressive periodontitis, or by smoking status. bacterial counts and proportional distributions were assessed in 84 individuals with chronic periodontitis and 22 with aggressive periodontitis. no differenc ... | 2008 | 18502971 |
| an interleukin-1beta (il-1beta) single-nucleotide polymorphism at position 3954 and red complex periodontopathogens independently and additively modulate the levels of il-1beta in diseased periodontal tissues. | inflammatory cytokines such as interleukin-1beta (il-1beta) are involved in the pathogenesis of periodontal diseases. a high individual variation in the levels of il-1beta mrna has been verified, which is possibly determined by genetic polymorphisms and/or by the presence of periodontopathogens such as porphyromonas gingivalis, tannerella forsythia, treponema denticola, and aggregatibacter actinomycetemcomitans. in this study, we investigated the role of an il-1beta promoter single-nucleotide po ... | 2008 | 18541658 |
| pcr-based identification of selected pathogens associated with endodontic infections in deciduous and permanent teeth. | the aim of the present study was to evaluate the presence of the selected pathogens in samples from deciduous and permanent tooth root canals by using pcr method and to determine the association of these organisms with clinical symptoms. | 2008 | 18547832 |
| [relationship between herpesviruses and periodontal pathogenic bacteria in subgingival plaque]. | to evaluate the prevalence rates of human cytomegalovirus(hcmv) and epstein-barr virus-1(ebv-1) in subgingival plaque and analyze the relationship between herpesviruses, periodontal pathogenic bacteria and periodontal clinical parameters in chinese patients with aggressive periodontitis(agp). | 2008 | 18560463 |
| rapid and simple detection of eight major periodontal pathogens by the loop-mediated isothermal amplification method. | loop-mediated isothermal amplification (lamp) was applied to develop a rapid and simple detection system for eight periodontal pathogens: aggregatibacter (actinobacillus) actinomycetemcomitans, campylobacter rectus, eikenella corrodens, fusobacterium nucleatum, porphyromonas gingivalis, prevotella intermedia, treponema denticola and tannerella forsythia. primers were designed from the 16s ribosomal rna gene for each pathogen, and the lamp amplified the targets specifically and efficiently under ... | 2008 | 18565108 |
| distribution of 10 periodontal bacterial species in children and adolescents over a 7-year period. | there is scant information available regarding the distribution of periodontal bacterial species in children and adolescents over an extended period. the purpose of this study was to compare bacterial profiles in the same individuals over a period of 7 years. | 2008 | 18565147 |
| analysis of neutrophil-derived antimicrobial peptides in gingival crevicular fluid suggests importance of cathelicidin ll-37 in the innate immune response against periodontogenic bacteria. | during periodontitis, an innate immune response to bacterial challenge is primarily mediated by neutrophils. we compared neutrophilic content and the level of neutrophil-derived antimicrobial peptides in gingival crevicular fluid (gcf) in two clinical forms of severe periodontitis. | 2008 | 18582333 |
| relationship of porphyromonas gingivalis with glycemic level in patients with type 2 diabetes following periodontal treatment. | the aim of this study was to assess the relationship between serum glycemic levels and subgingival microbial profile alteration following periodontal treatment in patients with type 2 diabetes mellitus. | 2008 | 18582336 |
| clinical and laboratory evaluations of non-surgical periodontal treatment in subjects with diabetes mellitus. | the aim of this study was to evaluate the clinical and laboratory changes 3 months after full-mouth scaling and root planing in subjects with and without diabetes mellitus. | 2008 | 18597596 |
| treatment outcomes of dental flossing in twins: molecular analysis of the interproximal microflora. | the purpose of this study was to assess the effects of dental flossing on the microbial composition of interproximal plaque samples in matched twins. | 2008 | 18672992 |
| the adjectival form of the epithet in tannerella forsythensis sakamoto et al. 2002 is to be retained and the name is to be corrected to tannerella forsythia sakamoto et al. 2002. opinion 85. | the judicial commission rules that the adjectival form is to be conserved in the specific epithet forsythia in tannerella forsythia. | 2008 | 18676491 |
| disease severity associated with presence in subgingival plaque of porphyromonas gingivalis, aggregatibacter actinomycetemcomitans, and tannerella forsythia, singly or in combination, as detected by nested multiplex pcr. | this study used a nested multiplex pcr method to detect three periodontal pathogens in subgingival plaque collected before treatment and at 2 and 6 months posttreatment from 107 patients with severe, generalized periodontitis. the proportions of the patients who harbored these bacteria before periodontal treatment were as follows: tannerella forsythia, 81%; porphyromonas gingivalis, 78%; and aggregatibacter (formerly actinobacillus) actinomycetemcomitans, 47%. at 2 months posttreatment there was ... | 2008 | 18701660 |
| clinical and microbiological benefits of systemic metronidazole and amoxicillin in the treatment of smokers with chronic periodontitis: a randomized placebo-controlled study. | the aim of this study was to evaluate the clinical and microbiological effects of scaling and root planing (srp) alone or combined with metronidazole (mtz) or with mtz and amoxicillin (amx) in the treatment of smokers with chronic periodontitis. | 2008 | 18727657 |
| root canal microbiota of teeth with chronic apical periodontitis. | samples from infected root canals of 43 teeth with chronic apical periodontitis were analyzed for the presence and relative levels of 83 oral bacterial species and/or phylotypes using a reverse-capture checkerboard hybridization assay. associations between the most frequently detected taxa were also recorded. the most prevalent taxa were olsenella uli (74%), eikenella corrodens (63%), porphyromonas endodontalis (56%), peptostreptococcus anaerobius (54%), and bacteroidetes oral clone x083 (51%). ... | 2008 | 18768651 |
| photodynamic therapy as an adjunct to non-surgical periodontal treatment: a randomized, controlled clinical trial. | recent preclinical and clinical data have suggested a potential benefit of photodynamic therapy (pdt) in the treatment of periodontitis. however, there are very limited data from controlled clinical trials evaluating the effect of pdt in the treatment of periodontitis. the aim of this study was to evaluate the clinical and microbiologic effects of the adjunctive use of pdt to non-surgical periodontal treatment. | 2008 | 18771363 |
| a 5-year longitudinal study of tannerella forsythia prth genotype: association with loss of attachment. | tannerella forsythia (previously t. forsythensis) in subgingival plaque has been recognized as a defined periodontal pathogen, but its mere presence may be insufficient for disease initiation and/or progression. the organism may produce a cysteine protease, encoded by the prth gene, which may play a role in the transition from commensal organism to opportunistic pathogen. this study aimed to relate changes in the level of t. forsythia prth genotype over a 5-year period to a concomitant loss of a ... | 2008 | 18166104 |
| one-year bacterial colonization patterns of staphylococcus aureus and other bacteria at implants and adjacent teeth. | (i) to assess the pattern of early bacterial colonization on titanium oral implants after installation, at 12 weeks and at 12 months, (ii) to compare the microbiota at submucosal implant sites and adjacent subgingival tooth sites and (iii) to assess whether or not early colonization was predictive of 12-month colonization patterns. | 2008 | 18177429 |
| clinical and microbiological analysis of subjects treated with brånemark or astratech implants: a 7-year follow-up study. | to assess the impact of different implant systems on the clinical conditions and the microbiota at implants, and whether the presence of bacteria at tooth sites was predictive of the presence at implant sites. | 2008 | 18261121 |
| increased interleukin-18 in gingival crevicular fluid from periodontitis patients. | this study aimed to measure the levels of interleukin-18 (il-18) in inflamed shallow sites and inflamed deep sites in patients with periodontitis and to compare the data with results from inflamed shallow sites in patients with gingivitis. a secondary aim was to examine the composition of the subgingival microbiota in the sampled sites. | 2008 | 18279187 |
| etiological analysis of initial colonization of periodontal pathogens in oral cavity. | it is unclear when the initial colonization by periodontal pathogens occurs in the oral cavity. therefore, we report here the association between specific age groups and the time when the initial colonization by periodontal pathogens occurs in the oral cavity in such groups. findings are based on an epidemiological analysis of the prevalence of five periodontal pathogens in the oral cavities of a wide range of age populations, from newborn to elderly, who were randomly selected in a geographic r ... | 2008 | 18287326 |
| pro-inflammatory cytokine production from normal human fibroblasts is induced by tannerella forsythia detaching factor. | tannerella forsythia is a periodontal pathogen. recently, we have reported that the cytopathic component of t. forsythia contains two distinct factors. one arrests the cell cycle at the g2 phase and the other, named forsythia detaching factor, detaches adhesion-dependent immortalized human cells. in this study, we investigated the biological function of forsythia detaching factor using human normal fibroblasts. | 2008 | 18302614 |
| colonization pattern of periodontal bacteria in japanese children and their mothers. | the purpose of this study was to determine the time of infection by anaerobic gram-negative rods associated with periodontal disease, and to clarify their transmission from mother to child. | 2008 | 18302616 |
| microbial changes in patients with acute periodontal abscess after treatment detected by padotest. | to investigate changes in bacterial counts in subgingival plaque from patients with acute periodontal abscess by iai-padotest. | 2008 | 18302679 |
| tannerella forsythia and pseudomonas aeruginosa in subgingival bacterial samples from parous women. | information on the subgingival microbiota in parous women is limited. the present study assessed 74 bacterial species at periodontal sites. | 2008 | 18315434 |
| osteoporosis and oral infection: independent risk factors for oral bone loss. | studies have suggested that oral bone loss is independently influenced by local and systemic factors, including osteoporosis. this cross-sectional study of 1256 post-menopausal women, recruited from the buffalo center of the women's health initiative observational study, evaluated the influence of oral infection and age on the associations between osteoporosis and oral bone loss. systemic bone density was measured by dual-energy x-ray absorptiometry. alveolar crestal height was measured from sta ... | 2008 | 18362312 |
| periodontal pathogens and gestational diabetes mellitus. | in previous cross-sectional or case-control studies, clinical periodontal disease has been associated with gestational diabetes mellitus. to test the hypothesis that, in comparison with women who do not develop gestational diabetes mellitus, those who do develop it will have had a greater exposure to clinical and other periodontal parameters, we measured clinical, bacteriological (in plaque and cervico-vaginal samples), immunological, and inflammatory mediator parameters 7 weeks before the diagn ... | 2008 | 18362313 |
| site-specific development of periodontal disease is associated with increased levels of porphyromonas gingivalis, treponema denticola, and tannerella forsythia in subgingival plaque. | porphyromonas gingivalis, treponema denticola, and tannerella forsythia (previously t. forsythensis), which are regarded as the principal periodontopathogenic bacteria, exist as a consortium in subgingival biofilms. we aimed to examine quantitative relationships between p. gingivalis, t. denticola, and t. forsythia in subgingival biofilms and the relationship between the quantity and prevalence of these three bacteria and site-specific periodontal health. | 2008 | 18380560 |
| interleukin-6 polymorphisms are associated with pathogenic bacteria in subjects with periodontitis. | growing evidence suggests that individual genetic susceptibility may influence the host's response to infections. previously, we showed that a common variation in the interleukin (il)-6 gene was associated with increased odds of detection of common periodontal pathogens from individuals with aggressive periodontitis. the aim of this study was to investigate the association between il-6 polymorphisms and periodontopathogenic bacteria in a larger, ethnically mixed population of subjects with perio ... | 2008 | 18380561 |
| [detection of periodontal pathogens in coronary atherosclerotic plaques]. | to explore the possible correlation between coronary heart disease and periodontitis. | 2008 | 18380965 |
| salivary microbiota of hiv-positive children and its correlation with hiv status, oral diseases, and total secretory iga. | this study aimed to investigate the prevalence and levels of salivary microorganisms in hiv-positive children, and their correlation to hiv status, oral lesions, and salivary iga levels. | 2008 | 18384349 |
| salivary detection of periodontopathic bacteria in periodontally healthy children. | salivary occurrence of periodontopathic bacteria is of interest especially in children as a risk indicator for the transmission, development and control of periodontal disease. we assessed the prevalence of aggregatibacter actinomycetemcomitans, porphyromonas gingivalis, tannerella forsythia, prevotella intermedia, prevotella nigrescens and treponema denticola as microbial complexes in the saliva of children with mixed dentition and healthy gingiva. | 2008 | 17869137 |
| clinical and microbiological determinants of ailing dental implants. | the failure of the host tissue to establish or maintain osseointegration around dental implants is due to either occlusal or parafunctional forces, premature loading, ill-directed stress, or microbial infection. the long-term failure rate of dental implants is generally 5-10%. although a variety of etiologies of early peri-implant bone loss (from implant placement to 1-year post-loading) have been proposed, factors associated with late implant failures are less well understood but are probably r ... | 2009 | 18384407 |
| potential biomarkers of human salivary function: a modified proteomic approach. | in previous studies, we defined groups of subjects with opposite salivary function. group membership was associated with clinically relevant outcomes. high aggregation-adherence (haa) groups showed lower levels of caries, supragingival plaque, total streptococci, and tannerella forsythensis than low high aggregation-adherence (laa) groups. in this study, we used a proteomic approach to search for biomarkers which could be useful as risk indicators for those outcomes. | 2009 | 18804197 |
| clinical and microbiological effects of an essential-oil-containing mouth rinse applied in the "one-stage full-mouth disinfection" protocol--a randomized doubled-blinded preliminary study. | the aim of this randomized double-blinded preliminary study was to evaluate the clinical and microbiological long-term effects of an essential-oil-containing mouth rinse as the active agent utilized in the "one-stage full-mouth disinfection protocol." probing pocket depth and plaque and gingival indices were evaluated by the same calibrated examiner in all teeth of 20 moderate chronic periodontitis subjects. presence of aggregatibacter actinomycetemcomitans, porphyromonas gingivalis, and tannere ... | 2009 | 18716800 |
| photodynamic therapy as adjunct to non-surgical periodontal treatment in patients on periodontal maintenance: a randomized controlled clinical trial. | recent preclinical and clinical data have suggested the potential benefit of photodynamic therapy (pdt) in the treatment of periodontitis. however, currently, there are very limited data from controlled clinical trials evaluating the effect of pdt in the treatment of periodontitis. the aim of the present study was to evaluate the clinical and microbiological effects of the adjunctive use of pdt in non-surgical periodontal treatment in patients receiving supportive periodontal therapy. twenty-fou ... | 2009 | 18465191 |
| differences in subgingival microflora of korean and german periodontal patients. | the goal of this study was to characterize the microbiological profile in samples of subgingival plaque taken from periodontal patients with different ethnic origin. | 2009 | 19058781 |
| alendronate augments interleukin-1beta release from macrophages infected with periodontal pathogenic bacteria through activation of caspase-1. | nitrogen-containing bisphosphonates (nbps) are anti-bone-resorptive drugs with inflammatory side effects that include osteomyelitis and osteonecrosis of the jaw. oral bacteria have been considered to be a trigger for these nbp-associated jaw bone diseases. the present study examined the effects of alendronate (a typical nbp) and clodronate (a non-nbp) on the production of proinflammatory cytokines by macrophages infected with porphyromonas gingivalis and tannerella forsythia, which are important ... | 2009 | 19063908 |
| t-rflp-based mcra gene analysis of methanogenic archaea in association with oral infections and evidence of a novel methanobrevibacter phylotype. | increasing evidence suggests a role for methanogenic archaea (methanogens) in human health and disease via syntrophic interactions with bacteria. here we assessed the prevalence and distribution of methanogens and possible associations with bacteria in oral biofilms. | 2009 | 19702957 |
| comparisons of subgingival microbial profiles of refractory periodontitis, severe periodontitis, and periodontal health using the human oral microbe identification microarray. | this study compared the subgingival microbiota of subjects with refractory periodontitis (rp) to those in subjects with treatable periodontitis (grs = good responders) or periodontal health (ph) using the human oral microbe identification microarray (homim). | 2009 | 19722792 |
| distribution of periodontopathic bacterial species in japanese children with developmental disabilities. | recent developments in molecular biological techniques have enabled rapid detection of periodontopathic bacterial species in clinical specimens. accumulated evidence suggests that detection of specific bacterial species enables identification of subjects at high risk for the onset of periodontitis. we investigated the distribution of 10 selected periodontopathic bacterial species in dental plaque specimens obtained from children with disabilities who were attending daycare centers. | 2009 | 19772671 |
| clinical periodontal and microbiologic parameters in patients with acute myocardial infarction. | the aim of this study was to evaluate the impact of clinical periodontal parameters and the presence of periodontal pathogens in patients with acute myocardial infarction (ami). | 2009 | 19792846 |
| salivary interleukin-1beta concentration and the presence of multiple pathogens in periodontitis. | this study aimed to find salivary enzymes and/or cytokines that would reflect periodontitis, alone or in combination with salivary microbial markers. | 2009 | 19799718 |
| differential ability of periodontopathic bacteria to modulate invasion of human gingival epithelial cells by porphyromonas gingivalis. | periodontitis is a polymicrobial infection caused by selected gram-negative bacteria including porphyromonas gingivalis. host cell invasion by p. gingivalis has been proposed as a possible mechanism of pathogenesis in periodontitis. the aim of the present study was to assess the influence of periodontopathogens on p. gingivalis invasion of gingival epithelial cells in polymicrobial infection. p. gingivalis was tested for its ability to invade a human gingival epithelial cell line ca9-22 in co-in ... | 2009 | 19818393 |
| tannerella forsythia detected in infected root canals using nested pcr. | this study assessed the occurrence of tannerella forsythia in patients with acute and chronic primary endodontic infections. | 2009 | 19824556 |
| progression of chronic periodontitis can be predicted by the levels of porphyromonas gingivalis and treponema denticola in subgingival plaque. | chronic periodontitis is an inflammatory disease of the supporting tissues of the teeth associated with bacteria. diagnosis is achieved retrospectively by clinical observation of attachment loss. predicting disease progression would allow for targeted preventive therapy. the aim of this study was to monitor disease progression in patients on a maintenance program and determine the levels of specific bacteria in subgingival plaque samples and then examine the ability of the clinical parameters of ... | 2009 | 19832799 |
| subgingival bacterial colonization profiles correlate with gingival tissue gene expression. | periodontitis is a chronic inflammatory disease caused by the microbiota of the periodontal pocket. we investigated the association between subgingival bacterial profiles and gene expression patterns in gingival tissues of patients with periodontitis. a total of 120 patients undergoing periodontal surgery contributed with a minimum of two interproximal gingival papillae (range 2-4) from a maxillary posterior region. prior to tissue harvesting, subgingival plaque samples were collected from the m ... | 2009 | 19835625 |
| real-time polymerase chain reaction quantification of porphyromonas gingivalis and tannerella forsythia in primary endodontic infections. | porphyromonas gingivalis and tannerella forsythia are anaerobic bacteria commonly involved in root canal infections. although previous investigations have assessed these species by strictly qualitative approaches, accurate determination of their cell levels by a sensitive quantitative technique may contribute with additional information regarding relevance in pain of endodontic origin. | 2009 | 19840640 |
| microbiologic changes in subgingival plaque after removal of fixed orthodontic appliances. | to evaluate changes that occur in the subgingival microbiota after removal of fixed orthodontic appliances using polymerase chain reaction (pcr). | 2009 | 19852608 |
| do periodontopathogens disappear after full-mouth tooth extraction? | to monitor the intra-oral microbiological changes after full-mouth extraction using quantitative polymerase chain reaction (qpcr). | 2009 | 19930094 |
| changes in the incidence of periodontal pathogens during long-term monitoring and after application of antibacterial drugs. | the incidence of potential periodontal pathogens (aggregatibacter actinomycetemcomitans, formerly actinobacillus actinomycetemcomitans, tannerella forsythia, porphyromonas gingivalis, prevotella nigrescens, prevotella intermedia and capnocytophaga ochracea) was monitored in patients with chronic periodontitis and in healthy control subjects. two types of studies were carried out in which the composition of the bacterial communities in different niches of the same oral cavity ecosystem was invest ... | 2009 | 19937216 |