Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| a retrospective survey on side effects of praziquantel among 25,693 cases of schistosomiasis japonica. | a retrospective survey involving 25,693 persons was carried out in four provinces and the city of shanghai, china between december 1981 until may 1982 to document relatively serious side effects of praziquantel used in a mass treatment programme for schistosomiasis japonica. only 122 or 0.47% of those participating in the study had experienced relatively serious side reactions to the drug. most had only one kind of side effects but two or more were recorded in a few patients. neuropsychiatric re ... | 1983 | 6673126 |
| [clinical observation on schistosomiasis japonica treated with amoscanate and phenithionate in a hyperendemic area]. | 1983 | 6673935 | |
| [pathologic study on 53 cases of schistosomiasis japonica with hepatitis b]. | 1983 | 6673936 | |
| identification of species-specific and gender-specific proteins and glycoproteins of three human schistosomes. | species-specific and gender-specific polypeptides of schistosoma haematobium, schistosoma japonicum, and schistosoma mansoni have been identified. proteins of these schistosomes were metabolically labeled in vitro with 35s-methionine and their total proteins, concanavalin-a binding glycoproteins, released (shed or secreted) proteins, and released glycoproteins compared by two-dimensional polyacrylamide electrophoresis. many of the released proteins were glycosylated, and most of the synthesized ... | 1983 | 6674449 |
| identification of sex of schistosome larval stages. | sex of schistosoma mansoni cercariae was identified by a c-banding technique; interphase nuclei of females exhibited w-chromatin (heterochromatin of the w chromosome) whereas those of males did not. similar sexual dimorphism was also shown in nuclei of s. mansoni miracidia, sporocysts, and adult worms. cercariae of the following schistosomes could not be sexed by examination of nuclei after the c-band technique: s. japonicum, s. haematobium, and schistosomatium douthitti . the method presented w ... | 1983 | 6674459 |
| [case of schistosomiasis japonica with hepatic calcification]. | 1983 | 6674599 | |
| [scanning electron microscopy of the tegumental surface of a mainland strain of schistosoma japonicum]. | 1983 | 6678625 | |
| [comparative study on various dose schedules of praziquantel in the treatment of schistosomiasis japonica]. | 1983 | 6678627 | |
| [a preliminary report on the polyethylene glycol precipitation test to study the kinetics of circulating immune complexes in sera from rabbits infected with the cercariae of schistosoma japonicum]. | 1983 | 6678632 | |
| [determination of specific antibodies, igg, igm and ige, in schistosomiasis japonica by elisa and its clinical significance]. | 1983 | 6678657 | |
| [pyrimidine metabolism in schistosoma japonicum]. | 1983 | 6678666 | |
| [preliminary study on the in vitro cultivation of lung-phase schistosomula of schistosoma japonicum]. | 1983 | 6678667 | |
| characterization of monoclonal antibodies against schistosoma mansoni. | monoclonal antibodies directed against schistosoma mansoni antigens were produced by the in vitro fusion of b lymphocytes, obtained from mice infected with s. mansoni, and sp2/0 myeloma cells. antibody reactivity was assessed by elisa binding, utilizing 4 m kcl extracts of cercariae and adult worms, soluble egg antigen (sea), and purified antigenic preparations, and by indirect immunofluorescence using living schistosomula. the monoclonal antibodies recognized a wide spectrum of antigenic determ ... | 1983 | 6681690 |
| eosinophil chemotactic factor in schistosome eggs: a comparative study of eosinophil chemotactic factors in the eggs of schistosoma japonicum and s. mansoni in vitro. | significant chemotactic activity for eosinophils was detected in soluble egg antigen (sea) preparations of both schistosoma japonicum and s. mansoni in dose-dependent fashion. the activity of s. japonicum sea was higher than that of s. mansoni sea. gel filtration on sephadex g-150 showed that s. japonicum sea was composed of two groups of eosinophil chemotactic factors (ecfs), one of high molecular weight (jee-h) and the other of low molecular weight (jee-l). s. mansoni sea showed ecf compositio ... | 1983 | 6682296 |
| the measurement of ascaris suum protein by radioimmunoassay in sera from patients with helminthiasis and with gastrointestinal diseases. | in this study, we have developed a reliable radioimmunoassay (ria) for ascaris suum protein (asp) and have measured the serum concentration of asp in control subjects and in patients with helminthiasis and a variety of gastrointestinal diseases. the cross-reactivities of asp antibody with other helminth worm antigens were also measured by ria. ascaris lumbricoides contained approximately the same amount of asp antigenic substance as did ascaris suum. toxocara canis had a high concentration of a ... | 1983 | 6682964 |
| competitive radioimmunoassays using hybridoma and anti-idiotype antibodies in identification of antibody responses to, and antigens of, schistosoma japonicum. | a hybridoma-derived monoclonal antibody, i.134, with apparent specificity for schistosoma japonicum adult worms has immunodiagnostic potential for schistosomiasis japonica in the philippines. sera from known infected individuals will inhibit the binding of 125i-labelled i.134 to a crude adult worm extract (awe) in a competitive radioimmunoassay (cria), although a 10% false negative rate has been noted. another monoclonal antibody, p.41, which produces circumoval precipitation (cop) reactions wit ... | 1983 | 6683499 |
| reduce embryonation of schistosoma japonicum eggs as a contributory mechanism in modulation of granuloma in chronically sensitized mice. | 1983 | 6685346 | |
| a minimum essential medium for cultivation of schistosoma japonicum eggs. | 1983 | 6686980 | |
| [extraction, fractionation and chemical and immunological properties of urea-soluble schistosoma japonicum egg antigen]. | 1983 | 6687215 | |
| [enzyme-linked circumoval precipitation technic (elcopt) in the diagnosis of schistosomiasis japonica]. | 1983 | 6687217 | |
| [effect of levamisole on the granulomatous response to schistosoma japonicum eggs in mice]. | 1983 | 6687218 | |
| [artificial induction of specific immune modulation on schistosoma japonicum egg granulomas]. | 1983 | 6687219 | |
| mechanism of action of praziquantel on the eggs of schistosoma japonicum. | the mode of action of praziquantel on schistosoma japonicum eggs was examined in mice and in vitro. in a long term oogram observation of mouse intestine, lasting from 1 to 56 days after oral administration of 100 mg/kg 4 times in one day, many empty egg shells were observed from the next day. immature eggs, however, were not killed, but developed into miracidia that later degenerated into granulated and calcified eggs. in the oograms of mouse, from 5 to 240 minutes after a single oral dose of 10 ... | 1983 | 6687311 |
| genetic control of immune responses to schistosoma japonicum antigen. | a high-titre ige-antibody response to schistosoma japonicum antigen (sj) is obtained if helper t cells are appropriately induced by the infection. the antibody responses were found to be regulated by a gene(s) linked to the major histocompatibility complex. strains of h-2a and h-2k haplotypes were high responders, whereas h-2d, h-2b and h-2s strains were not. results obtained by using intra-h-2 recombinant strains suggested that the immune-response (ir) gene was mapped in the i-e subregion, alth ... | 1983 | 6219331 |
| schistosoma mansoni adult microsomal antigens, a serologic reagent. ii. specificity of antibody responses to the s. mansoni microsomal antigen (mama). | the purified schistosoma mansoni adult microsomal antigen, mama, was used in the quantitative single-tube kinetic dependent enzyme-linked immunosorbent assay (k-elisa) to measure antibody levels of various human patient sera. the 511 serum specimens tested were from patients with both homologous and heterologous infections. sera from u.s., egyptian, brazilian, and puerto rican patients infected with s. mansoni reacted strongly with mama. chinese patients infected with s. japonicum, and nigerians ... | 1983 | 6185578 |
| specificity of antibody and cellular immune responses in human schistosomiasis. | thirty patients infected with schistosoma mekongi, s. mansoni or s. japonicum had cell-mediated immune responses assessed by lymphocyte transformation in vitro (lt), immediate hypersensitivity responses determined by basophil histamine release in vitro (hr) and igg antibody responses evaluated in an enzyme-linked immunosorbent assay (elisa). species specificity was evaluated with antigens obtained from adult worms or eggs of the three schistosome species. though cross-reactivity was present in a ... | 1983 | 6186153 |
| sj23, the target antigen in schistosoma japonicum adult worms of an immunodiagnostic hybridoma antibody. | an igg2a mouse hybridoma-derived antibody (designated i.134) has been identified which binds to schistosoma japonicum adult worms and which has immunodiagnostic potential (for detection of antibody) in schistosomiasis japonica in the philippines. the target epitope of this hybridoma antibody is contained in a 23 000 molecular weight protein of adult worms as analysed by one-dimensional sodium dodecyl sulphate-polyacrylamide gel electrophoresis of immunoprecipitates and a gel overlay technique. t ... | 1983 | 6186977 |
| schistosoma japonicum: immunological characterization and detection of circulating polysaccharide antigens from adult worms. | the antigenic constituents of a trichloroacetic acid (tca)-soluble fraction of adult schistosoma japonicum were studied with immunoelectrophoresis, and compared with those of schistosoma mansoni. eight tca-soluble antigens of s. japonicum were demonstrated, five of which showed immunological identity with s. mansoni antigens. of the eight antigens, five antigens with anodic motility were found as circulating antigens in s. japonicum-infected hamster and rabbit sera; the major circulating antigen ... | 1983 | 6187594 |
| antigen-specific suppressor t lymphocytes (leu-2a+3a-) in human schistosomiasis japonica. | immunoregulatory mechanisms in human schistosomiasis japonica were investigated through in vitro t lymphocyte-macrophage co-culture experiments. high responder t lymphocytes responded to the schistosomal adult worm antigen in the presence of hla-dr-compatible low responder macrophages, whereas low responder t lymphocytes failed to respond to this antigen even in the presence of hla-dr-compatible high responder macrophages. this observation strongly suggested that t lymphocytes, but not macrophag ... | 1983 | 6195267 |
| cell-mediated and humoral immune responses in capuchin monkeys infected with schistosoma japonicum or schistosoma mansoni. | cell-mediated immune responses, assessed by lymphocyte clonal expansion in vitro, as well as humoral responses, assessed by an enzyme-linked immunosorbent assay (elisa), were evaluated in capuchin monkeys during a 7-month infection with schistosoma mansoni or with a japanese or philippine strain of schistosoma japonicum. although mounting a vigorous antibody response against parasite antigens, the s. mansoni-infected monkeys failed to show lymphocyte proliferation in response to stimulation with ... | 1983 | 6196978 |
| associations between hla and immune responses in individuals with chronic schistosomiasis japonica. | the association of an hla specificity with low or high immune responsiveness to schistosoma japonicum antigen (sj) was demonstrated among individuals who had previously been exposed to s. japonicum infection. the frequency of hla-aw24 specificity among low responders in the igg antibody response determined by the enzyme-linked immunosorbent assay (elisa) was higher than that among high responders. significant association between hla-b7 and high responsiveness was observed in the ige antibody res ... | 1984 | 6205482 |
| schistosoma mansoni, s. haematobium, and s. japonicum: identification of genus- and species-specific antigenic egg glycoproteins. | immunoreactive egg glycoproteins of schistosoma mansoni, s. haematobium, and s. japonicum which are genus- and species-specific, or react with sera of patients infected with other parasites, have been identified. egg proteins were labeled with iodine-125, and the concanavalin a-binding glycoproteins were immunoprecipitated with sera of patients infected with one of four species of schistosoma or trichinella spiralis, taenia solium, echinococcus granulosus, entamoeba histolytica, or wuchereria ba ... | 1984 | 6209162 |
| identity of antigens in adult tegument, gut, egg and cercaria of schistosoma japonicum by immunofluorescent study. | specificity of antigens in the different stages and tissues, i.e., gut and tegument of the adult worm, cercaria and egg of schistosoma japonicum (sj) were examined by the direct and indirect immunofluorescent antibody method with various immune rabbit sera. antigenic properties were completely different between gut of adult worms and egg. cross-reactions, however, occurred among egg, tegument and stroma of adult worms. this cross-reacting antigen in tegument appeared to be unstable against forma ... | 1984 | 6084086 |
| characterization of the carbohydrates of schistosoma japonicum adult worm, egg and cercaria by analysis of lectin binding and antibody reaction. | binding of the fitc-labeled lectins, con a, sba, wga, dba, uea 1 and rca 120 were examined on various kinds of cross-sections of s. japonicum adult worms and eggs, and on cercaria specimens. the specificity of the lectin bindings was examined by inhibition test with specific carbohydrates or with unlabeled lectins. furthermore, the locations of lectin binding in schistosomes were compared with those of the antigen-antibody reactions using the fluorescence technique. it was also studied as to whe ... | 1984 | 6085582 |
| [an autopsy case of bronchiolo-alveolar cell carcinoma with many schistosoma japonicum ova in the involved lung]. | 1984 | 6087002 | |
| eosinophil and neutrophil chemotactic activities of adult worm extracts of schistosoma japonicum in vivo and in vitro. | large numbers of eosinophils and neutrophils attracted to the soluble extract of schistosoma japonicum adult worms (sjaw-ext) were detected at the injection site of normal guinea pig skin. eosinophil and neutrophil chemotactic activities were also confirmed in in vitro assay by using blind-well chambers with millipore filters in dose-dependent fashion. two components of sjaw-ext showed eosinophil chemotactic activity; one was in the high molecular weight fraction (jae-h), estimated to be more th ... | 1984 | 6098637 |
| schistosoma mansoni, s. haematobium, and s. japonicum: identification of genus-, species-, and gender-specific antigenic worm glycoproteins. | immunoreactive glycoproteins of schistosoma mansoni, s. haematobium, and s. japonicum adult worms which are genus-, species-, and gender-specific, or react with sera of patients infected with other parasites, have been identified. schistosomes were metabolically labeled with [35s]methionine and the concanavalin-a binding glycoproteins that were immunoprecipitated with sera of patients infected with one of three species of schistosoma or trichinella spiralis, taenia solium, echinococcus granulosu ... | 1984 | 6692879 |
| schistosoma mansoni: detection and characterization of schistosome derived antigens by inhibition enzyme-linked immunosorbent assay (ielisa) utilizing monoclonal antibodies. | monoclonal antibodies were used in an inhibition enzyme-linked immunosorbent assay (ielisa) to detect a variety of schistosome derived antigens. preparations were obtained from various stages of schistosoma mansoni and from the eggs of s. japonicum. using appropriate titers of monoclonal antibodies it was possible to detect less than 0.01 micrograms/ml of schistosome antigens. the sensitivity of ielisa was dependent upon the type and concentration of the monoclonal antibody used, as well as upon ... | 1984 | 6695533 |
| depressed in vitro and in vivo antibody response and adoptive transfer of delayed hypersensitivity to myoglobin with spleen cells of mice chronically infected with schistosoma japonicum and injected with myoglobin. | spleen cells from c57bl/6j mice infected for 21 weeks with schistosoma japonicum did not show an in vitro secondary antibody response upon challenge with sperm whale myoglobin. mice infected for 13 weeks showed almost no in vivo secondary antibody response to this antigen. spleen cells from mice infected for 12 to 21 weeks did not adoptively transfer delayed hypersensitivity to this antigen. | 1984 | 6698605 |
| demonstration of species-specific and cross-reactive components of the adult microsomal antigens from schistosoma mansoni and s. japonicum (mama and jama). | analysis of human serum reactivities to the schistosoma mansoni adult microsomal antigens (mama) showed that s. japonicum and s. haematobium infection sera, as a rule, did not react as well to mama as did the homologous s. mansoni infection sera. the degree of species specificity, although not absolute, was quite pronounced. purification of the corresponding microsomal antigens from s. japonicum adults (jama) and subsequent assays with both homologous and heterologous infection sera show a disti ... | 1984 | 6715885 |
| [a comparison of the superficial argentophilic structures of miracidia from 12 species of the genus schistosoma]. | observation of miracidia of twelve species of schistosoma shows the fundamental epidermal cell pattern is: 6, 9, 4, 3. comparison of superficial argentophilic organites permits us: --to divide these species into three inequal groups: mansoni group: schistosoma mansoni, s. rodhaini. haematobium group: s. haematobium, s. bovis, s. indicum , s. intercalatum, s. margrebowiei , s. mattheei, s. nasale and s. spindale . japonicum group: s. japonicum, s. incognitum . --to emphasize the relatively narrow ... | 1984 | 6721370 |
| susceptibility of snail vectors to oriental anthropophilic schistosoma. | laboratory experiments were carried out to study the susceptibility of snail vectors to oriental anthropophilic schistosoma. oncomelania hupensis hupensis was readily infected with the local strain of schistosoma japonicum (chinese strain), and also infected with s. japonicum (philippines strain). o.h. quadrasi was only susceptible to its s. japonicum (philippines strain). the oncomelania races were refractory to s. mekongi, s. japonicum-like species (malaysian strain). tricula aperta (beta race ... | 1984 | 6740384 |
| [a seroepidemiological survey on schistosomiasis japonicum]. | 1984 | 6744396 | |
| further experience with praziquantel in schistosoma japonicum infections. | 1984 | 6428832 | |
| a field trial of a new serological method for the diagnosis of schistosomiasis. | 1984 | 6429257 | |
| [isolation of the antigens of schistosoma japonicum and their clinical application]. | 1984 | 6432250 | |
| hla and schistosomiasis japonica. | 1984 | 6440750 | |
| [use of the colonic microscope in the diagnosis of schistosomiasis japonicum]. | 1984 | 6442621 | |
| genetic control of immune responses to schistosoma japonicum. | the mouse ige antibody response to s. japonicum antigen (sj) was found to be under control of a gene(s) linked to the major histocompatibility complex. in some strains but not all among low responders, however, t cell responsiveness to sj could be demonstrated by the induction of carrier effect as well as by proliferation response. resistance to reinfection with a large dose of s. japonicum cercariae was demonstrated in most strains examined, except c57bl/6, irrespective of the immune responsive ... | 1984 | 6442944 |
| preliminary studies on the mode of action of pyquiton against schistosoma japonicum. | 1984 | 6443276 | |
| scanning electron microscopic study on hepatoportal phase schistosomula of schistosoma japonicum. | 1984 | 6443286 | |
| [a solid enzyme immunoassay using nylon disc for the detection of specific antibodies of schistosoma japonicum]. | 1984 | 6380807 | |
| variations of titers of immunofluorescent antibody against cercaria, adult and egg antigens developed in rabbits infected with schistosoma japonicum before and after treatment with praziquantel. | the antibody titers of schistosoma japonicum infected rabbits were examined against different antigens in various stages of s. japonicum using the indirect immunofluorescent antibody test with fitc-labeled anti-rabbit-gamma-globulin. the first immunofluorescent reaction could be demonstrated in the gut of adult worms 3 to 4 weeks after infection, depending on the strength of infection, then 2 weeks later within the egg shell and on the cercaria and about 1 more week later in the tegument of adul ... | 1984 | 6384587 |
| phase iii clinical trials with praziquantel in s. japonicum infections in the philippines. | following successful phase ii clinical studies with praziquantel (2-cyclohexylcarbonyl-1,2,3,6,7,11b-hexahydro-4h-pyrazino [2,1-a]isoquinolin-4-one, embay 8440, biltricide), expanded field trials of phase iii were conducted in mindoro oriental, leyte and davao norte, to reassess efficacy, safety and acceptability of the drug on a larger scale. a total of 6,134 cases were treated with the best tolerated and effective dose of 60 mg/kg bwt which for practical purposes was given in 2 instead of 3 di ... | 1984 | 6391506 |
| [comparison of different methods of the circumoval precipitin test (copt) for schistosomiasis japonica. field evaluation of the copt group]. | 1984 | 6391723 | |
| [preliminary study on monoclonal antibodies against schistosoma japonicum]. | 1984 | 6391725 | |
| [immunofluorescence circumoval precipitin test in the diagnosis of schistosomiasis japonica]. | 1984 | 6391726 | |
| [preliminary application of elisa of liver sections of infected mice in the diagnosis of schistosomiasis japonica]. | 1984 | 6391727 | |
| [amino acid composition of antigens of schistosoma japonicum eggs and the adult schistosoma japonicum, paragonimus westermani and clonorchis sinensis]. | 1984 | 6391728 | |
| the presence of anti-sheep red blood cell heterophile antibodies and their characteristics in murine schistosomiasis japonica. | sensitive methods of an enzyme-linked immunosorbent assay (elisa) using red blood cells (rbc) have been developed and were applied to the detection of anti-sheep red blood cell (srbc) heterophile antibodies (ab) present in sera of schistosoma japonicum (sj)-infected mice. the indirect hemagglutination test (iha) was used for the purpose as well. by these methods a significant increase in the heterophile ab levels was demonstrated in the mice particularly after 6-10 weeks of infection. the hetero ... | 1984 | 6394971 |
| the kinetics of hepatosplenic schistosomiasis. | 1984 | 6395341 | |
| detection of malaysian schistosomiasis in orang asli of peninsular malaysia using serodiagnostic tests. | 1984 | 6398916 | |
| experiences with praziquantel against schistosoma japonicum infection in the philippines. | 1984 | 6398917 | |
| [antibody detection (ifat, elisa) in experimental schistosoma japonicum-infected goats]. | 1984 | 6370227 | |
| differentiation of schistosomes by species, strain, and sex by using cloned dna markers. | we have detected species, strain, and sex-specific genetic markers for the genus schistosoma by southern blot analysis of its dna using cloned dna segments of the schistosoma mansoni ribosomal gene as probes. restriction analysis of dna from eight different strains of s. mansoni, from africa and the caribbean, revealed that the predominant or major dna fragment containing the ribosomal gene unit was the same in each but that low copy number or minor fragments containing the gene varied. it was s ... | 1984 | 6322176 |
| factors affecting the acquisition of resistance to schistosoma japonicum in the mouse. ii. evidence that resistance to reinfection is not mediated by specific effector mechanisms. | the skin phase of schistosomular migration was neither essential for the induction or expression of acquired resistance since mice given primary infections by the intraperitoneal route were as resistant to intraperitoneal or percutaneous challenge as were mice given their primary infections percutaneously. serum taken from resistant donors with acute or chronic infections conferred no ability to resist infection upon recipient mice. in two experiments mice that were deprived of their t-cells wer ... | 1984 | 6334269 |
| retroperitoneal fibrosis associated with schistosoma japonicum infestation--an immunologically mediated disease? | a patient with s. japonicum infestation of the liver presented with acute renal failure due to retroperitoneal fibrosis, together with the presence of low complement levels, anti-nuclear and anti-dna antibodies. renal failure responded to intravenous bolus methylprednisone and later definitive surgery, with complement levels returning to normal after the acute episode. the findings are consistent with the hypothesis that retroperitoneal fibrosis may be a local manifestation of a systemic immune ... | 1984 | 6334390 |
| three cases of schistosomiasis mekongi from northern laos. | three cases of intestinal schistosomiasis acquired in northern laos are reported. all three patients swam regularly for many years in the mekong river near the cities of vientiane and luang prabang. morphology of the eggs found on rectal biopsy indicated infection with schistosoma mekongi. one patient had severe portal hypertension with bleeding esophageal varices requiring a splenorenal shunt; studies of her liver biopsy showed s. mekongi eggs and periportal fibrosis. a second patient had abnor ... | 1984 | 6334449 |
| [preliminary observation on the activity of t lymphocyte acid alpha-naphthyl acetate esterase in the blood of patients with schistosomiasis japonica]. | 1984 | 6334576 | |
| [effects of artemether on schistosoma japonicum adult worms and ova]. | 1984 | 6232824 | |
| [histological observation on the effects of praziquantel on schistosomulae of schistosoma japonicum in mouse skin]. | 1984 | 6232825 | |
| [purine metabolism in schistosoma japonicum]. | 1984 | 6240356 | |
| [effects of pyquiton on pulmonary s. japonicum egg granulomas in sensitized mice]. | 1984 | 6241053 | |
| [isolation and preliminary analysis of surface membrane antigen from adult worm of schistosoma japonicum]. | 1984 | 6241070 | |
| the metabolism of pyrimidine and purine in schistosoma japonicum. | 1984 | 6242289 | |
| [cerebral schistosomiasis with a huge calcification. a case report]. | a case of cerebral schistosomiasis with a huge calcification and with a long clinical course was reported. a 39-year-old male developed ataxic gait gradually associated with headache and general fatigability. according to the past history, the patient had suffered from severe meningitis with disturbance of consciousness for 2 weeks when he was 10 years of age. neurological examination revealed positive romberg's sign and left homonymous hemianopsia. plain craniogram showed a large calcification ... | 1984 | 6462358 |
| [seroepidemiology of schistosomiasis japonica. i. age distribution in antibody response of populations living in three areas of varied endemicity]. | 1984 | 6467533 | |
| [isolation and immunoactive characterization of tegumental membrane proteins from adult schistosoma japonicum]. | 1984 | 6467535 | |
| [preliminary observation on the cercaria of schistosoma japonicum by scanning electron microscopy]. | 1984 | 6467550 | |
| differences in hepatic fibrosis and granuloma size in several strains of mice infected with schistosoma japonicum. | mice of several strains were exposed to schistosoma japonicum cercariae and killed 6, 7, 10, or 15 weeks later. hepatic fibrosis was consistently most marked in icr mice and least marked in c57bl/6, a and c57bl/ks mice. intermediate degrees of fibrosis were present in c3h, cba and nmri mice. the size of circumoval granulomas also varied greatly among mouse strains but the degree of hepatic fibrosis was unrelated to granuloma size, indicating that the mechanisms regulating granuloma size may not ... | 1984 | 6476205 |
| spontaneous and egg antigen-induced syntheses of immunoglobulin and antibody by spleen cells and hepatic granulomas of mice infected with schistosoma japonicum. | in the absence of egg antigen (sea), spleen cells from c57bl/6 mice infected for 22 weeks with schistosoma japonicum were spontaneously induced in vitro to synthesize total immunoglobulin and antibody to sea. hepatic granulomas from mice infected for 12 weeks, but not for 22 weeks, also showed spontaneous syntheses of total immunoglobulin and antibody to sea, but these syntheses were not enhanced upon the addition of sea. total immunoglobulin production was enhanced when sea was added to spleen ... | 1984 | 6480111 |
| schistosoma japonicum and colorectal cancer: an epidemiological study in the people's republic of china. | prevalence of infestation with schistosoma japonicum was highly correlated with mortality from colorectal cancer in 89 communes in four counties of jiangsu province, china (rank correlation coefficient = 0.68) in 1973-75, and with incidence of colorectal cancer in 24 communes of haining county, zhejiang province in 1977-79. no similar correlations were seen with lung cancer. the presence or absence of a past history of schistosomiasis was ascertained from 154 patients with cancer of the rectum, ... | 1984 | 6480152 |
| [comparative efficacy of oltipraz (1 dose, 30 mg/kg) and the combination of niridazole (25 mg/kg) and metrifonate (10 mg/kg) against s. haematobium]. | pugh (1978) and teedsale et al. (1980) showed that an associated single dose of metrifonate (12.5 mg/kg) plus niridazole (25 mg/kg) gave good results on schistosoma haematobium: the egg-reduction percentage ranged between 84.7 and 91.2. in niger, we compared the effects of this medication to oltipraz in a single dose (30 mg/kg). we selected a dosage of 10 mg/kg of metrifonate and 25 mg/kg of niridazole. this trial was carried out during the minimal transmission period. --109 adults (greater than ... | 1984 | 6482729 |
| seroepidemiology of schistosomiasis japonica by elisa in the philippines. ii. unreliability of stool examination in the measurement of incidence. | it was shown in a previous study that a single quantitative stool examination (by technics currently used in the philippines) is so sensitive that it underestimated by 50% the prevalence of schistosomiasis japonica in children detected by a single serologic assay (elisa). this paper proves that measurement of incidence of the infection among these same children by stool examination is unreliable as well. three important sources of error in the measurement of incidence by stool examination are: ( ... | 1984 | 6486296 |
| seroepidemiology of schistosomiasis japonica by elisa in the philippines. iii. selective mass chemotherapy with praziquantel in a control program. | after a pre-control (pre-treatment) prevalence rate of schistosomiasis japonica was established by stool examination and by elisa in about 400 school children in school year 1979, annual prevalence rates were measured in the following 3 assessment years. from 54-80% of children found infected primarily by stool examination were treated with praziquantel 3-9 months before the assessment examinations. both stool examination and elisa showed statistically significant reductions of prevalence from t ... | 1984 | 6486297 |
| vaccination of bovines against schistosomiasis japonica with highly irradiated schistosomula in china. | vaccination of chinese bovines (cattle and buffaloes) against schistosomiasis japonica with 36 kr gamma-irradiated schistosomula was done for laboratory challenge and for field trials in china. altogether, 61 bovines were used. all experimental animals were vaccinated 2-3 times with 10,000 irradiated schistosomula per time. for the laboratory challenge, all experimental and control cattle were challenged with 500 normal cercariae and each buffalo, with 2,000 cercariae. the laboratory-challenged ... | 1984 | 6486298 |
| [studies on the schistosomicidal mechanism of fluoroacetic acid]. | 1984 | 6496101 | |
| a cohort study on the causes of death in an endemic area of schistosomiasis japonica in japan. | in order to elucidate the chronic effects of schistosomiasis japonica, a retrospective cohort study was carried out. the mortality experience of 2,067 inhabitants over 30 years old in the endemic area of schistosomiasis in yamanashi prefecture were followed up from 1958 to 1982 concerning the underlying cause of death. total person-years at risk were 18,694.1 for males and 21,524.9 for females. the observed-expected ratio (o/e) was significantly high for cirrhosis of the liver (4.05 for males, 5 ... | 1984 | 6497313 |
| factors affecting the acquisition of resistance to schistosoma japonicum in the mouse. i. the correlation between egg deposition and worm elimination. | acquired resistance to schistosoma japonicum was evident after the lung phase of migration of challenge schistosomula. 'trickle' infections which gave similar primary worm burdens to single infections stimulated similar levels of resistance. there was a strong correlation between the size of the primary worm burden of individual mice and their ability to resist infection 8 weeks after exposure to s. japonicum. however, acquired resistance did not develop until 6 weeks, that is after the primary ... | 1984 | 6504563 |
| susceptibility of oncomelania hupensis subspecies to infection with geographic strains of schistosoma japonicum. | subspecies of oncomelania hupensis were exposed to infection with zoophilic and anthropophilic strains of schistosoma japonicum. the snails were philippine o. h. quadrasi from the islands of bohol, leyte and mindanao, o. h. formosana from changhua and ilan, and o. h. chiui from taiwan, o. h. hupensis from china, o. h. nosophora from japan and o. h. lindoensis from indonesia. anthropophilic strains of s. japonicum were from bohol and leyte in the philippines, china, japan and indonesia. the zooph ... | 1984 | 6505785 |
| effects of cercarial concentration and length of exposure on the infection of mice by schistosoma japonicum and s. mekongi cercariae. | the effects of cercarial concentration and length of exposure on the infection of mice by schistosoma japonicum and s. mekongi were studied under laboratory conditions. for all cercarial concentrations of 10, 20 and 30, mice exposed for 1 min acquired little or no infection. total worm recovery tended to rise with an increase either in cercarial concentration or exposure time. the highest infection rate and worm burden were obtained in mice exposed for 64 min to 30 cercariae per mouse. the prese ... | 1984 | 6505791 |
| effects of physico-chemical factors on the infection of mice with schistosoma japonicum and s. mekongi cercariae. | the three physico-chemical characteristics of water tested-ph, temperature and salinity were found to affect the infection of mice by cercariae of s. japonicum and s. mekongi. for both species of schistosomes, the range of optimal ph that showed highest infection and worm recovery rates was between 5.4-7.4 and decreased as the ph increased. cercariae exposed to temperatures between 15 degrees-30 degrees c showed the highest infection and worm recovery rates. as temperature decreased or increased ... | 1984 | 6505792 |
| a case of schistosomiasis japonica: resolution of cat-scan detected cerebral abnormalities without specific therapy. | a 28-year-old marine corps officer developed katayama fever with central nervous system (cns) manifestations 6 weeks after swimming on leyte island in the philippines. symptoms consisted of fever, nausea and vomiting, focal visual field deficits and mild confusion. cat-scan of the patient's head initially revealed multiple lucencies and severe edema in the left frontal, parietal and occipital lobes. no schistosome eggs were found in the patient's stool, and therefore he was treated with a 10-wee ... | 1984 | 6507728 |
| [ectopic localization of adult schistosoma japonicum in the kidney]. | 1984 | 6509731 | |
| [detection of schistosoma japonicum antigens and antibodies by k-elisa]. | 1984 | 6509736 | |
| [studies on the microsomal antigens of schistosoma japonicum. ii. extraction, fractionation and chemical and immunological properties of microsomal antigens of adult worms]. | 1984 | 6509737 | |
| [experimental therapy of hepatic fibrosis in schistosomiasis japonica. ii. effect of colchicine on hepatic fibrosis]. | 1984 | 6509741 | |
| [effect of artemether on the tegumental surface antigen of schistosoma japonicum]. | 1984 | 6509742 | |
| comparison of protein composition between schistosomula of schistosoma japonicum and s. mansoni. | sds-page analysis revealed that the protein composition of mechanically transformed schistosomula (ms) of a japanese strain of schistosoma japonicum was essentially similar to that of a philippine strain of s. japonicum. however, the protein components of s. mansoni ms were remarkably different from those of s. japonicum. specific proteins of mr 60-65 and 30 kda were found in ms of s. japonicum and s. mansoni, respectively. in skin-penetrated schistosomula (ss) of the two species, a common prote ... | 1984 | 6514378 |
| a case-control study on liver cancer with special emphasis on the possible aetiological role of schistosomiasis. | in order to elucidate the relationship between liver cancer and suspected aetiological factors, a case-control study was carried out at seven hospitals in yamanashi prefecture, where the mortality rate of the disease was significantly higher than the corresponding national figure. this prefecture was also recognised as one of the endemic areas for schistosoma japonicum in japan. sixty-two cases of liver cancer, and the same number of controls were selected during the two-year study period. a ski ... | 1984 | 6519877 |