Publications

radical cure of chesson strain vivax malaria in man by 7, not 14, days of treatment with primaquine.	glucose-6-phosphate dehydrogenase-normal adult volunteers infected with mosquito-bone chesson strain vivax malaria were treated with chloroquine and primaquine during the initial attack. administration of 60 mg (base) of primaquine daily for 7 days was as effective in preventing relapse as is the regimen customarily used for the radical cure of infections produced by this strain, namely, 30 mg daily for 14 days. however, it is stressed that because of the risk of primaquine-induced hemolysis in ...	1977	326072
[transmission of the brazilian strain of tertian malaria by anopheles maculipennis atroparvus mosquitoes].		1977	327252
malaria field studies in a high-incidence coastal area of el salvador, c.a.	a three-year investigation was made of the incidence patterns and characteristics of malaria in a small high-incidence coastal area of el salvador with a resident population of about 6,000 persons and a migrant population of 3,000 to 4,000 others. it found a significant increase in the incidence of plasmodium falciparum cases during the three-year period, combined with relative stability in the annual number of plasmodium vivax cases. a close correlation was observed between the seasonal occuren ...	1977	328096
malaria and hereditary ovalocytosis.	hereditary ovalocytosis in papua new guinea is restricted to areas of endemic malaria and may confer increased resistance to the disease. the incidence of malaria was investigated in 1616 melanesiams of known red cell morphology and severity of infection determined in a smaller subsample. ovalocytics tended to be more resistant to severe malarial infections than normocytics. the ratio of parasitaemia in 112 ovalocytics compared with 741 normocytic children was 1.05 for p. falciparum; 0.90 for p. ...	1977	328370
the prevention and treatment of malaria.		1977	329080
congenital malaria: a rare cause of splenomegaly and anemia in an american infant.	a 38-day-old infant had fever, jaundice, hepatosplenomegaly, and a hemolytic anemia. a peripheral blood smear demonstrated intraerythrocytic malarial parasites identified as plasmodium vivax. maternal and infant sera contained antibodies to this species. a directed history revealed the mother had suffered several febrile illnesses in mexico during her pregnancy. malaria had not been diagnosed nor was it considered at the time of her delivery at this hospital. review of this and six other cases o ...	1977	329210
[obscure diagnosis of malaria (author's transl)].		1977	329379
morphologic variants of anopheles albimanus and susceptibility to plasmodium vivax and p. falciparum.	three morphologically different, true-breeding phenotypes have been isolated from a strain of anopheles albimanus from lake apastepeque, el salvador. studies with coindigenous strains of plasmodium vivax and p. falciparum show that these phenotypes differ significantly in their susceptibility to malaria parasites. this difference is apparent both in the number of mosquitoes that become infected and the level of infection obtained. variations in malaria susceptibility are markedly greater with p. ...	1977	329696
crossreactivity with sporozoites, exoerythrocytic forms and blood schizonts of plasmodium berghei in indirect fluorescent antibody tests with sera of rats immunized with sporozoites or infected blood.	ifa studies are reported using plasmodial antigens from three different stages of the life cycle of plasmodium berghei: sporozoites (sp); exoerythrocytic schizonts in rat liver (eef); and parasitized rat erythrocytes (sch = schizonts). two series of specific sera were applied: sera from adult rats with a blood-induced infection (series a) and sera from rats immunized against sporozoites by mosquito bites and protected against parasitaemia by chloroquine (series b). in series a antibody titres wi ...	1977	330066
[tertiary malaria with acute lung edema in a turkish child].	in the past 10-15 years there has been a continuous increase of imported cases of malaria in the federal republic of germany. the case of a two-year-old child of a turkish foreign worker with severe tertian malaria complicated by pulmonary edema is described. in general tertian malaria is rarely fatal to adults, but in children the primary attack can be life threatening.	1977	336495
efficacy of 5-day radical treatment of p. vivax infection in tamil nadu.		1977	336529
[identification of plasmodial antibodies in the immunodiagnosis of malaria (author's transl)].	out of 880 sera which were examined for antibodies to plasmodia 69 (7.8%) reacted only with p. falciparum antigen, 371(42.2%) reacted only with p. fieldi antigen, and 440 (50%) responded to both antigens. these groups were differentiated further with antigens from p. vivax, p. ovale, and p. malariae. the results showed that the p. ovale antigen was distinguished by a marked activity with those sera that had reacted only with p. fieldi in the screening test. with sera that had responded to both a ...	1977	337074
population studies of plasmodium vivax. 1. the theory of polymorphism of sporozoites and epidemiological phenomena of tertian malaria.	the understanding of clinico-epidemiological phenomena of tertian malaria has been the subject of controversy. the authors suggest a system of postulates which give a non-contradictory explanation of the phenomena of relapses and long incubation. the main idea is that the duration of exoerythrocytic development of plasmodium vivax is a polymorphic characteristic controlled by a set of genes. according to these postulates sporozoites may be subdivided into two groups designated as tachysporozoite ...	1977	338188
population studies of plasmodium vivax. 2. distribution of manifestations in foci of tertian malaria.	the authors investigate a mathematical model based on the theory they proposed in a previous publication. the model fits field data collected in re-established foci of tertian malaria. the patterns of distribution of manifestations of tertian malaria among the population may readily be explained on the basis of the theory of polymorphism of sporozoites.	1977	338189
the duffy blood group and malaria prevalence in gambian west africans.	erythrocytes from 1,168 donors, comprising almost the entire populations of two rural gambian villages, have been tested for duffy blood group antigens using antisera to both fya and fyb. all tests were negative. blood film examination of the same samples showed complete absence of plasmodium vivax parasitaemia, but infections with p. falciparum,p. malariae and p. ovale were observed. the findings are consistent with the view that the duffy-negative phenotype, fyfy, constitutes the basis of inna ...	1977	339418
incubation and prepatent periods of plasmodium vivax.		1977	339427
comparison of treatment schedules for plasmodium vivax infections in the solomon islands.	a total of 26 patients infected with solomon islands strains of plasmodium vivax was treated with one of three regimens of cloroquine-primaquine, in an attempt to determine the relapse patterns and the response to treatment of the local strains of parasite. the results suggest that the standard course of chloroquine-primaquine provides a radical cure for the strains of plasmodium vivax from the solomon islands, provided that strict supervision of drug administration is enforced.	1977	339599
the seroepidemiology of malaria in middle america. iv. passage of malaria antibodies from mothers to infants.	in an area of el salvador moderately endemic for malaria, use of the indirect fluorescent antibody test (ifa) showed that 44% of the infants born to mothers who had ifa responses to plasmodium vivax of 1:20 or higher during the latter part of their pregnancy had positive ifa responses of 1:10 or higher to this antigen. no serum from an infant was positive in the absence of some level of malarial response in the mother.	1977	339753
chemosuppressive field trials in thailand. iii. the suppression of plasmodium falciparum and plasmodium vivax parasitemias by a sulfadoxine-pyrimethamine combination.		1977	339754
[susceptibility of anopheles maculipennis atroparvus v. thiel to infection with the azerbaijan strains of plasmodium of tertian malaria (plasmodium vivax)].		1977	144846
malaria in the republic of the philippines. a review.	malaria in the republic of the philippines is caused principally by p. falciparum and p. vivax, with the former as predominant species. p. malariae is occasionally reported, while p. ovale is very rare and has been reported only in the island of palawan. malaria is widespread in distribution with prevalence varying from one area to the other. in 1970, the malaria morbidity rate was reported to be 77.6 per 100,000 while the mortality rate was 1.8 per 100,000. case detection activities revealed th ...	1977	21558
[malarial hepatitis. apropos of a case].		1977	206971
biomedical survey in irian jaya (west irian), indonesia.	a biomedical survey was conducted in several areas of irian jaya, indonesia in july 1972 in association with an investigation of reports of a cholera outbreak. stool specimens, blood smears and sera were collected and examined for evidence of parasitic as well as other infectious diseases. a total of 114 stools were examined and the most commonly found intestinal parasites were trichuris trichiura (94%), ascaris lumbricoides (74%), hookworm (58%), entamoeba coli (15%), endolimax nana (8%), entam ...	1977	208184
pathophysiology of atypical malaria.		1977	348670
clinical variants of malaria.		1977	348671
[parasitological diagnosis of malaria by concentration of parasitized erythrocytes: technic and preliminary results].		1977	354817
malaria in nottingham children.	in five and a half years 16 children were admitted to hospital in nottingham suffering from malaria. thirteen cases were caused by plasmodium vivax and two by p falciparum, and in one the type was not identified. all were children of immigrant parents, predominantly from pakistan, although most were born in england but had been visiting asia. three children were ill on or soon after arrival, but in the others the onset of symptoms was delayed by up to nine months. all made an uneventful recovery ...	1977	589173
malaria cases observed in gdańsk in 1973-1977.		1977	342009
response of p. vivax and p. falciparum cases to presumptive treatment with chloroquine in some districts of karnataka.		1977	346479
ultrastructural changes of the erythrocyte membrane in ovale-type malarial parasites.		1977	403266
studies on the santa lucia (el salvador) strain of plasmodium falciparum in aotus trivirgatus monkeys.	the santa lucia strain of plasmodium falciparum was isolated from el salvador, central america, and established in aotus trivirgatus monkeys. transmission from monkey to monkey via the bites of infected anopheles freeborni, a. maculatus, and a, albimanus mosquitoes was obtained in 20 of 27 attempts. prepatent periods in the monkeys ranged from 17 to 46 days with a mean of 24.3 days. parasitemias and mortality were higher following sporozoite inoculation into animals which had been previously inf ...	1977	403272
comparison of the curative antimalarial activities and toxicities of primaquine and its d and l isomers.	this investigation was undertaken to determine whether either d-primaquine or l-primaquine has sufficient advantage over primaquine to warrant evaluation for curative activity in human volunteers infected with plasmodium vivax. it was found: (i) that the capacities of the isomers and the racemate to cure infections with plasmodium cynomolgi in rhesus monkeys were essentially identical; (ii) that the subacute toxicities of the isomers and racemate for this monkey were qualitatively the same, but ...	1977	407841
ficoll fractionation for the separation of parasitized erythrocytes from malaria infected blood.	separation and concentration of parasitized erythrocytes from infected blood was achieved by centrifugation of a sample placed in a layer on top of a cushion of a ficoll solution with a critical density. pure suspensions of parasitized erythrocytes were obtained from plasmodium berghei infected rodent blood, whereas results with p. vivax infected monkey (aotus trivirgatus) blood were partially successful. titration experiments revealed that the parasitized erythrocytes obtained by ficoll fractio ...	1977	408020
quantitative aspects of pyrimethamine-sulfonamide synergism.	the experiments described in this report have dealt with the dimensions of therapeutic potentiation achieved when combinations of pyrimethamine and sulfadiazine were administered to rhesus monkeys infected with a drug-susceptible strain of plasmodium cynomolgi or its pyrimethamine-resistant variant and to owl monkeys infected with strains of p. falciparum and p. vivax of varying degrees of resistance to this pyrimidine. these evaluations showed: 1) that when delivered in combination, the activit ...	1977	410317
hypothesis on the mechanism of erythrocyte invasion by malaria merozoites.	plasmodium knowlesi merozoites invade erythrocytes by a sequence of events: attachment, widespread deformation of the erythrocyte membrane, endocytosis, and resealing of the membrane and vesicle. the possible mechanisms by which these events occur are discussed. in particular, there is a detailed discussion of the role of the duffy blood group system in invasion.	1977	412599
erythrocyte receptors for malaria merozoites.		1977	413448
[connatal malaria (author's transl)].	a case of connatal malaria due to plasmodium vivax in a newborn of turkish origin is presented. most likely the infection was acquired by materno - fetal transfusion during labor. pathophysiological aspects and mode of transmission of this rare disease are discussed.	1977	340774
malaria in illinois.		1977	19393
plasmodium falciparum and plasmodium vivax infections in the owl monkey (aotus trivirgatus). ii. responses to chloroquine, quinine, and pyrimethamine.	the studies described in this report were designed to determine the responses of established infections with eight strains of plasmodium falciparum and two strains of p. vivax in owl monkeys to treatment with chloroquine, quinine, and pyrimethamine. responses with these different strains ranged from cure via application of well-tolerated doses of two of the above drugs and refractoriness to treatment with maximally tolerated doses of the third, to complete resistance to maximally tolerated doses ...	1978	99056
plasmodium falciparum and plasmodium vivax infections in the owl monkey (aotus trivirgatus). i. the courses of untreated infections.	this study, the first of three designed to determine the feasibility of using owl monkeys infected with human plasmodia in the search for new, more broadly active antimalarial drugs, dealt with the characteristics of untreated infections with eight strains of plasmodium falciparum and two strains of p. vivax. such infections, induced by standardized inocula of these strains in 1,733 monkeys, all aotus trivirgatus griseimembra, were followed from day of inoculation to death of self-cure. the viru ...	1978	99055
[hemiparkinsonism, probably due to malaria (author's transl)].		1978	348371
[malaria; a summary].		1978	348605
applications and possibilities of cytophotometry for red cell hematology.		1978	368884
[clinical problems in current malaria. considerations apropos of 2 cases].	two cases of malaria imported from west africa by two sailors (falciparum and vivax respectively) are reported. it is pointed out that nowadays malaria is no longer indigenous to sicily but has to be imported; an increasing number of cases of malaria are being reported world-wide in relation to increased traffic volumes, particularly air traffic. this means growing importance of imported pathology for which a new training strategy is required (with regard to young physicians who at present are q ...	1978	342993
chemoprophylaxis and malaria in american servicemen returning from vietnam.	information relating to chemoprophylaxis and malaria in 49 men who served with the united states armed forces in vietnam and who developed overt malaria after departure from vietnam indicated that: 1) compliance with intended chemoprophylactic regimens was far optimal; 2) a history of recent prophylactic ingestion of chloroquine was not a reliable indicator of infection with chloroquine-resistant plasmodium falciparum: 3) reported ingestion of half or more of an intended terminal chemoprophylact ...	1978	343607
babesia microti infection in man: evaluation of an indirect immunofluorescent antibody test.	an indirect immunofluorescent antibody test was used to detect antibody to babesia microti in human sera. nine patients from nantucket island, massachusetts infected with b. microti had serum titers greater than or equal to 1,024. of 84 control sera from new york city residents, 246 sera from patients with possible exposure to ticks, and 36 sera from patients with suspected or confirmed tick bites, none was reactive at titers of 1:16 or above. the within-test reproducibility was within one fourf ...	1978	343608
clinical and hematologic peculiarities of malaria in infancy. a study of 40 infants.		1978	346290
observations on malaria in an industrial area of chotonagpur.		1978	383847
the experimental infection of anopheles litoralis king from luzon island, philippines, by plasmodium vivax.		1978	373132
determination of antibody titres in human malaria using the indirect haemagglutination test.		1978	374268
plasmodium vivax malaria in the neonatal period.		1978	374271
the chloroquine resistant chronic vivax malaria presenting as malarial cachexia and secondary hypersplenism: (a case report).		1978	355141
topical aspects of the epidemiology of malaria.		1978	355188
the duffy blood group and resistance to plasmodium vivax in honduras.	to test the hypothesis that the duffy blood group negative genotype is a factor in resistance to plasmodium vivax, we determined the duffy blood group, the malaria antibodies, and the slide-demonstrated infection rates with p. vivax and p. falciparum of 420 persons living in nueva armenia, honduras. in all, 247 persons were duffy negative. demonstrated infections with p. falciparum were almost equally distributed between duffy-positive (5,8%) and duffy-negative (4.9%) persons. similarly, duffy-p ...	1978	356634
[5 cases of imported malaria].		1978	358306
malaria and pregnancy.	a review of current literature on the effects of malaria on pregnant women and the foetus is made and its effective control is discussed. the role of placenta as an exchange organ and as the first defence line for foetus is also described. reduced resistance to malaria during pregnancy may be due to immunological and hormonal changes. in malarious areas, the effective control of malaria results in reduced maternal anaemia and in increased birth-weights. prophylaxis, treatment and other antimalar ...	1978	358656
[malaria introduced into switzerland from 1974-1976].	in recent years there has been an increase in imported tropical diseases in switzerland. travellers to the tropics are often inadequately or not at all informed about the dangers and possible prophylaxis of infection. this is true for malaria, of which 207 cases covering the years 1974 to 1976 are studied. most involved were people between 21 and 30 years old. the main infections (71%) come from african countries. plasmodium falciparum was found somewhat more frequently than p. vivax. only a sev ...	1978	360380
susceptibility to vivax malaria in ethiopia.	plasmodium vivax prevalence rates for nilotic and hamitic-semitic residents of an ethiopian town were compared. over a ten-year period, 8,316 blood films from nilotes were examined and 59 p. vivax infections (0.7%) were diagnosed. in 1,630 films from hamito-semites, 75 probable p. vivax infections (4.6%) were found. the problem of morphological differentiation between p. vivax and p. ovale was evaded by combining the two diagnoses. p. vivax/ovale infection rates for hamitic-semitic subjects were ...	1978	360496
prevalence of chloroquine resistance in malaria.		1978	361680
malaria in lakshadweep islands.		1978	363613
[control of malaria and its eradication in the socialist republic of vietnam].		1978	364292
primaquine phosphate is the drug of choice.		1978	364396
trends in the development of chemotherapy for parasitic diseases.		1978	364672
human parasitoses of the malili area, south sulawesi (celebes) province, indonesia.	a biomedical survey was conducted in 9 villages in the malili area of south sulawesi, indonesia. blood specimens were examined for malaria and microfilariae; stool specimens were examined for intestinal parasites. malaria parasitemias were rare; plasmodium falciparum was detected in 10 and p. vivax in 11 of 985 blood smears. malayan filariasis was endemic to all villages surveyed. the overall prevalence of detectable microfilaremias was 15%, varying from 34% in kawata to 1% in nuha. microfilaria ...	1978	364674
standardization of the indirect fluorescent antibody test for malaria.	methods are described whereby results of malarial immunofluorescence tests can be evaluated objectively. the ifa test was quantitated by standardizing the physical system against a fluorescent standard and preparation of biological standards of malarial antisera and fluorescein labelled conjugates. using these known standards the reactivity of antigens was characterized. it was found that antigen preparations are best when they include mature schizonts, and keep best when they are stored in a dr ...	1978	364783
the duffy blood group phenotype in american blacks infected with plasmodium vivax in vietnam.	we determined blood group phenotypes of 13 blacks who were infected with plasmodium vivax in vietnam. all were duffy blood group positive as compared to 40--50% duffy positive in surveys of black blood donors in the united states. the probability that 13 of 13 were duffy positive by chance alone was p less than 0.001. all other blood groups occurred at the expected frequency. this study is further support for the hypothesis that the duffy negative genotype (fyfy) is the basis for resistance of b ...	1978	365004
presumptive treatment of p. vivax and p. falciparum cases with 600 mg. chloroquine base in tamil nadu.		1978	365722
a comparative study of malaria prophylaxis in peninsular malaysia using chloroquine and a combination of sulphadoxine and pyrimethamine.		1978	366165
malaria: a new facet of heroin addiction in australia.	a case of vivax malaria is described. the patient, who had occasionally abused heroin intravenously, shared injection equipment with an addict who had previously contracted malaria in southeast asia and who had failed to complete an adequate course of treatment.	1978	366360
some aspects of epidemiology of resurgent malaria in turkey.	the resurgence of autochthonous plasmodium vivax malaria in turkey is a matter of considerable concern. anopheles sacharovi is the important vector but other species, notably a. superpictus, may play a role in transmission. the epidemiology is discussed in terms of factors related to the mosquito, factors related to the human host and human ecology as it affects dispersal of the parasite. although the development of insecticide resistance is grave, the present situation is mainly attributable to ...	1978	366812
[comparison of mosquito infectiosity with the causative agents of malaria from blood sucking on man and through a biomembrane].		1978	353474
[congenital malaria caused by plasmodium vivax (a case report)].		1978	353713
[receptivity of the vector a.l. atroparvus to 2 strains of p. vivax].		1978	353945
[imported malaria in the soviet and foreign citizens].		1978	354018
lymphocyte mitogenic factor in sera from patients with falciparum malaria.	to test for the presence of a lymphocyte mitogenic factor in malaria, sera were obtained from 10 patients with malaria (9 with falciparum and one with vivax), and 10 noninfected controls. the sera from the malarial patients caused an increased blastogenesis in mouse splenic lymphocyte cultures and inhibited hemagglutination between lipid-a-coated erythrocytes and lipid-a antibodies. none of the sera were positive using the limulus amebocyte lysate test. these results could be interpreted to demo ...	1978	354145
field evaluation of primaquine in the control of plasmodium vivax.	two regimens of primaquine in combination with amodiaquine have been compared with amodiaquine alone in known cases of plasmodium vivax in an endemic area of el salvador, c.a. a 5-day regimen of primaquine, with dosages based on an adult dose of 15 mg per day, produced a substantial reduction in the numbers of patients experiencing renewed parasite activity and in the number of parasitemias experienced by the group during 9 mo of posttreatment observation, when compared with patients treated onl ...	1978	354416
malaria in a honduras hunter.		1978	341334
transient an-alpha-lipoproteinaemia in man during infection by plasmodium vivax.		1978	77973
transient changes in serum lipoproteins during antimalarial therapy and malaria.		1978	80548
sensitivity of duffy negative erythrocytes in aotus monkeys to plasmodium vivax.		1978	97822
antimalarial activities of various 4-quinolonemethanols with special attention to wr-142,490 (mefloquine).	pilot appraisals of the activities of a selected group of 4-quinolinemethanols against acute plasmodium falciparum infections in owl monkeys indicated that compounds of this class are equally active against infections with chloroquine-resistant and chloroquine-susceptible strains and that this efficacy is not compromised by concomitant resistance to pyrimethamine, and in addition, identified three derivatives with outstanding activity (wr-226,253; wr-142,490; and wr-184,806). wr-142,490, the sec ...	1978	98104
antimalarial activities of various 4-pyridinemethanols with special attention to wr-172,435 and wr-180,409.	pilot appraisals of the activities of 10 specially selected 2,6-substituted-4-pyridinemethanols against acute plasmodium falciparum infections in owl monkeys identified three derivatives that were two to three times as active as chloroquine against infections with a 4-aminoquinoline-susceptible strain and, at the same doses, were equally effective against infections with a strain fully resistant to treatment with maximally tolerated doses of chloroquine, quinine, and pyrimethamine. two of these ...	1978	101132
[an epidemiological consideration of the status of infection in 29 patients with malaria (author's transl)].		1978	101609
antimalarial activities of wr-194,965, an alpha-amino-o-cresol derivative.	pilot appraisals of the activities of wr-194,965 and wr-204,165, two closely related o-cresol derivatives (both mannich bases), in owl monkeys infected with the multidrug-resistant vietnam smith strain of plasmodium falciparum showed that these compounds had similar levels of efficacy. total course doses effecting 90% cures (cd(90)s) were 27 and 37 mg/kg of body weight for the respective compounds, values almost identical to the cd(90) of mefloquine (a highly promising 4-quinolinemethanol) again ...	1978	103492
antimalarial activities of the 4-quinolinemethanols wr-184,806 and wr-226,253.	wr-184,806 and wr-226,253, two 4-quinolinemethanols structurally similar to wr-142,490 (mefloquine), have been studied in depth in owl monkeys infected with various drug-resistant and drug-susceptible strains of plasmodium falciparum and p. vivax in an effort to provide support and guidance for projected evaluations in human volunteers. the results of these studies, confirmatory of preliminary appraisals, showed that wr-184,806 was approximately one-third as active as wr-142,490 against infectio ...	1978	103493
[a new case of autochthonous malaria with probable contamination in an international airport of the paris region].		1978	356697
chemoprophylaxis of malaria.		1978	356694
plasmodium falciparum and plasmodium vivax infections in the owl monkey (aotus trivirgatus). iii. methods employed in the search for new blood schizonticidal drugs.	this report describes, illustrates, and validates the major features of a procedure designed to provide primary assessments of the activities of potential antimalarial drugs against infections with chloroquine-resistant or pyrimethamine-resistant strains of plasmodium falciparum in owl monkeys of colombian origin. studies with 14 specially selected compounds have shown that the test method has the capacity to identify and quantify diverse levels of therapeutic efficacy among agents that differ w ...	1978	99057
effect of sequential infection with plasmodium vivax and p. falciparum in the aotus trivirgatus monkey.	aotus trivirgatus monkeys with prior experience with plasmodium vivax were inoculated with p. falciparum via the bites of infected mosquitoes. the animals with prior malaria had higher parasitemias and significantly higher levels of mosquito infectivity than monkeys with no prior p. vivax experience. monkeys with a history of p. falciparum that were inoculated with p. vivax had essentially the same parasitemias as those with no prior malaria. however, levels of mosquito infectivity were markedly ...	1979	117086
[advantages of the errecart's technique for the identification of plasmodium (author's transl)].	errecart (1945) proposed a modified technique for making thick films for the diagnosis of chaga's disease. we applied his technique to the study of malaria in mammals; the morphology of the blood parasites is very well preserved and allows the identification of species which are frequently not identifiable in ordinary thick films.	1979	120125
[current information on treatment and prophylaxis of malaria (author's transl)].	malaria is not a disease of the past. as long as worldwide eradication has not been achieved there is a close connection between countries which export it and those which import it. if the european doctor is presently confronted with a feverish disease which may have been brought in from a tropical area, he should immediately think of malaria and take the necessary measures for treatment. if patients or travelers come into the office and enquire about drugs and preventive measures against malari ...	1979	120502
cause of anaemia in malaria.	51cr studies showed that after complete eradication of malarial parasites erythrocyte life-span is reduced for 4-5 weeks and that the reduction is associated with the presence of complement-containing immune complexes on the red-cell surface. the rate of erythrophagocytosis in the spleen is increased during this period. 59fe studies of erythropoiesis indicated a mild degree of marrow depression. a very important factor causing anaemia in malaria appears to be a complement-mediated immune process ...	1979	86777
increasing incidence of malaria in britain.		1979	87705
recurrent anaphylaxis due to plasmodium vivax infection.		1979	87792
complement activation by parasites. a review.	activation of complement by parasites (living parasites or purified parasite antigens) is involved in several mechanisms of the host parasite relationship. in most of the experiments performed in vitro, complement activation was found to be lethal for the parasites, but sometimes it could be essential for the development of parasitemia. both classical and alternative complement pathways may be activated by parasites; the classical pathway nearly always requires the involvement of antibodies wher ...	1979	35934
[chemotherapy of infections in the third world].		1979	162323
malaria in birmingham and a london teaching hospital.	during the past five years the incidence of imported malaria increased among patients seen in east birmingham hospital and in st thomas's hospital, london. plasmodium vivax was the predominant species in birmingham, and was almost always acquired by asian immigrants visiting the indian subcontinent. in st thomas's p falciparum was most commonly imported, usually by african immigrants visiting nigeria and ghana. two patients (one irish, one japanese) died of falciparum malaria after visiting trop ...	1979	367507
[tertian malaria in children and adults from an epidemic region in southern turkey (author's transl)].	since 1974 an epidemic of tertian malaria has been spreading around the adana and tarsus townships in southern turkey, with a peak incidence of 115 500 cases in 1977. a further increase is to be expected because the insect vectors have become resistant to insecticides. since 1975 eleven children and three adults have been treated for p. vivax malaria. they had all stayed in the epidemic area during the transmission season which lasts from july to october. because of a long primary latent period ...	1979	367741
occurrence of malaria acquired during travel abroad among american civilians, 1970-1976.		1979	374645
lymphocyte changes in murine and human malaria.		1979	375510