Publications

colorectal neoplasia: screening average risk individuals.		2006	1782367
angiokeratoma of the clitoris: a subtype of angiokeratoma vulvae.	a 24-year-old married woman had an angiokeratoma of the vulva measuring 3 x 3 x 4 mm localized at the clitoris. the nodule was noticed when she was pregnant with her first child. this tumor grew with occasional tenderness and bleeding during pregnancy, but its size did not change after delivery. the growth of this tumor might be attributable to an increase in venous pressure or serum progesterone levels; therefore this disorder might be classified as a subtype of angiokeratoma of the vulva. this ...	2006	1479114
thymocytopoiesis is maintained by blood-borne precursors throughout postnatal life. a study in parabiotic mice.	this study was designed to resolve the long standing controversy as to whether hematogenous precursors or resident intrathymic precursors maintain thymocytopoiesis in postnatal life. the kinetics of thymic chimerism was examined over a 21-wk period in 105 pairs of nonirradiated, thy-1-alloantigen-disparate, parabiotic b10.s mice. thymic chimerism reached reached maximum levels of 25% in the thy-1b and 16% in the thy-1a partners (mean 20.5% and 9.8%, respectively) 6 to 7 wk after parabiotic union ...	2006	1347301
colorectal neoplasia: screening average risk individuals.		2006	1782367
comparing clinical tests of visual loss in cataract patients using a quantification of forward light scatter.		2006	1794427
[serial biochemical and histological studies on fatty liver in obese patients].		2006	4087483
osteoporosis: whose problem is it?		2006	1540021
anterior chamber lens exchange.		2006	1489454
recent progress on obtaining theoretical and experimental support for the "e-pathway hypothesis" of coupled transmembrane electron and proton transfer in dihaem-containing quinol:fumarate reductase.	reconciliation of apparently contradictory experimental results obtained on the quinol: fumarate reductase (qfr), a dihaem-containing respiratory membrane protein complex from wolinella succinogenes, was previously obtained by the proposal of the so-called e-pathway hypothesis. according to this hypothesis, transmembrane electron transfer via the haem groups is strictly coupled to co-transfer of protons via a transiently established, novel pathway, proposed to contain the side chain of residue g ...	2006	16790236
[nurses and professional secret].		2006	3645907
[nurses and professional secret].		2006	3645907
study of acute intraoperative suprachoroidal hemorrhage.	acute intraoperative suprachoroidal hemorrhage or effusion (aish) was studied in a prospective manner over the past three years. in a general cataract surgery population of 2,523 patient eyes, 15 (0.6%) experienced an aish. results of a specific surgical management technique are presented. surgical control of the aish consisted of immediate closure of the incision and application of pressure directly to the eye. this tamponades the effusion or hemorrhage, which allows coagulation and completion ...	2006	1403754
the educational process at the mount sinai school of medicine: the first 25 years.	although the charter for the school of medicine was signed in 1963, and active recruitment of faculty commenced almost immediately, the recruitment of students, in fact, did not begin until several years later, with admission of a first-year and a third-year class in september 1968. from that time to the present, the class size has increased from a small, carefully selected group of 36 first-year students to its current size of 115 students in each of the basic science years and 132 students in ...	2006	2685587
a protocol system to satisfy research specific, disease specific, physician specific, and patient specific informational needs.	the department of medicine at loyola university medical center chicago (lumc) has developed and is utilizing a patient information protocol system (pips) to address clinical and research informational needs. pips, an integrated module of the department's patient information management system (pims), enables end-users to access pre-defined informational templates or "protocols". protocols detail pre-defined data requirements for patient management or clinical research needs. each protocol consist ...	2006	1482966
ion channel selectivity, permeation, and block.		2006	1382215
role of glutamine depletion in directing tissue-specific nutrient stress responses to l-asparaginase.	l-asparaginase is important in the induction regimen for treating acute lymphoblastic leukemia. cytotoxic complications are clinically significant problems lacking mechanistic insight. to reveal tissue-specific molecular responses to this drug, mice were administered asparaginase from either escherichia coli (clinically used) or wolinella succinogenes (novel, glutaminase-free form). both enzymes abolished serum asparagine, but only the e. coli form reduced circulating glutamine. e. coli asparagi ...	2006	16931516
case report: myocardial ischemia: an overlooked substrate in syncope of aortic stenosis.	the cause of the syncope in aortic stenosis has been the subject of controversy partly because only a few patients have been monitored during their syncopal episodes. among the mechanisms proposed are hypersensitive carotid sinus, complete a-v block, ventricular arrhythmias, and ischemic myocardial depression. it is now accepted that the syncope is caused by a vasodepressor response from stimulation of left ventricular baroceptors, resulting in reflex hypotension and bradycardia. this case repor ...	2006	1539605
vena tech vena cava filter: experience and early follow-up.	vena caval filters, such as the vena tech filter, that employ low-profile introducer systems have provided physicians with a variety of options for percutaneous placement. from april 1989 to april 1990, 81 patients underwent percutaneous placement of the vena tech filter at the authors' institution. follow-up has been obtained to evaluate the filter with regard to the prevention of pulmonary embolism, the maintenance of caval patency, and mechanical stability. two cases of pulmonary embolism hav ...	2006	1797208
vena tech vena cava filter: experience and early follow-up.	vena caval filters, such as the vena tech filter, that employ low-profile introducer systems have provided physicians with a variety of options for percutaneous placement. from april 1989 to april 1990, 81 patients underwent percutaneous placement of the vena tech filter at the authors' institution. follow-up has been obtained to evaluate the filter with regard to the prevention of pulmonary embolism, the maintenance of caval patency, and mechanical stability. two cases of pulmonary embolism hav ...	2006	1797208
[possibilities and limitations of a nursing department. nursing and politics].		2006	1618101
ossification of the posterior cervical longitudinal ligament.	forty patients with cervical myelopathy due to opll (ossification of the posterior longitudinal ligament) of the cervical spine were studied. according to abe's or yamamoto's classification, 12 of them had a 50% decrease in the cross-sectional area of the spinal canal. subtotal vertebrectomy was carried out in 8 of these patients and the remaining 4 patients received posterior decompression. we concluded that anterior decompression, if possible, is the treatment of choice and posterior decompres ...	2006	1595391
[insufficient treatment because of special payment. interview by bjørn arild ostby].		2006	1489614
regular processor control improves portal film quality.		2006	1557499
comparison of the structural and kinetic properties of the cytochrome c nitrite reductases from escherichia coli, wolinella succinogenes, sulfurospirillum deleyianum and desulfovibrio desulfuricans.	the recent crystallographic characterization of nrfas from sulfurospirillum deleyianum, wolinella succinogenes, escherichia coli and desulfovibrio desulfuricans allows structurally conserved regions to be identified. comparison of nitrite and sulphite reductase activities from different bacteria shows that the relative activities vary according to organism. by comparison of both amino acid sequences and structures, differences can be identified in the monomer-monomer interface and the active-sit ...	2006	16417505
multiple haem lyase genes indicate substrate specificity in cytochrome c biogenesis.	c-type cytochromes are a widespread class of proteins that play a vital role in the energy-conserving metabolism of prokaryotic and eukaryotic organisms. the key event in cytochrome c biogenesis is the covalent attachment of the haem cofactor to two (or rarely one) cysteine residues arranged in a haem c-binding motif such as cx(2-4)ch, cxxck or x(3)ch. this reaction is catalysed by the membrane-bound enzyme cchl (cytochrome c haem lyase). different cchls have been described and some of them are ...	2006	16417506
genome mapping of arcobacter butzleri.	a genome map of the potential food-poisoning pathogen arcobacter butzleri, strain nctc 12481, has been constructed. the map was ordered by a combination of one- and two-dimensional pulsed field gel electrophoresis, using the restriction enzymes eagi, sacii, sali and xhoi, and southern hybridization with digoxygenin-labelled probes. the size of the genome was estimated at 2.57+/-0.01 mb; this is 0.9 mb larger than the genome of the closely related species campylobacter jejuni. we deduce that ther ...	2006	16499619
genetic characterization of a single bifunctional enzyme for fumarate reduction and succinate oxidation in geobacter sulfurreducens and engineering of fumarate reduction in geobacter metallireducens.	the mechanism of fumarate reduction in geobacter sulfurreducens was investigated. the genome contained genes encoding a heterotrimeric fumarate reductase, frdcab, with homology to the fumarate reductase of wolinella succinogenes and the succinate dehydrogenase of bacillus subtilis. mutation of the putative catalytic subunit of the enzyme resulted in a strain that lacked fumarate reductase activity and was unable to grow with fumarate as the terminal electron acceptor. the mutant strain also lack ...	2006	16385034
heterologous production in wolinella succinogenes and characterization of the quinol:fumarate reductase enzymes from helicobacter pylori and campylobacter jejuni.	the epsilon-proteobacteria helicobacter pylori and campylobacter jejuni are both human pathogens. they colonize mucosal surfaces causing severe diseases. the membrane protein complex qfr (quinol:fumarate reductase) from h. pylori has previously been established as a potential drug target, and the same is likely for the qfr from c. jejuni. in the present paper, we describe the cloning of the qfr operons from the two pathogenic bacteria h. pylori and c. jejuni and their expression in wolinella suc ...	2006	16367742
evidence for transmembrane proton transfer in a dihaem-containing membrane protein complex.	membrane protein complexes can support both the generation and utilisation of a transmembrane electrochemical proton potential ('proton-motive force'), either by transmembrane electron transfer coupled to protolytic reactions on opposite sides of the membrane or by transmembrane proton transfer. here we provide the first evidence that both of these mechanisms are combined in the case of a specific respiratory membrane protein complex, the dihaem-containing quinol:fumarate reductase (qfr) of woli ...	2006	17024183
molecular signatures (unique proteins and conserved indels) that are specific for the epsilon proteobacteria (campylobacterales).	the epsilon proteobacteria, which include many important human pathogens, are presently recognized solely on the basis of their branching in rrna trees. no unique molecular or biochemical characteristics specific for this group are known.	2006	16817973
acute myocardial infarction after blunt chest trauma in young people: need for prompt intervention.	we describe four cases of acute myocardial infarction in young patients, secondary to blunt chest trauma. one case was treated with intracoronary thrombolysis and angioplasty, two cases received systemic thrombolysis, and the last one did not have any reperfusion therapy. the coronary angiograms of the left anterior descending artery showed thrombosis in two cases, coronary dissection in one case, and no morphological lesions in the other. we encourage the early performance of angiographic studi ...	2006	1764738
[fundus plication with or without proximal selective vagotomy?].	the aim of this study was to determine the influence of proximal gastric vagotomy on the outcome after fundoplication. of 141 patients operated on for reflux disease between 1972 and 1988, 53 had fundoplication alone (group a) and 88 fundoplication combined with proximal gastric vagotomy (group b). the two groups were similar with regard to the severity of the reflux disease (esophagitis: a 69%, b 73%) but had a different incidence of concomitant ulcer disease (a 2%, b 55%). after a mean follow- ...	2006	1621082
carbohydrate specificity of the receptor sites of mistletoe toxic lectin-i.	the carbohydrate specificity of mistletoe toxic lectin-i (ml-i) was studied by haemagglutination-inhibition assay. the results indicated that ml-i has a broad range of affinity for gal alpha,beta linked sequences. the galabiose (e, gal alpha 1----4gal) sequence, a receptor of the uropathogenic e. coli ligand, was one of the best disaccharide inhibitors tested. the lectin also exhibits affinity for lac(gal beta 1----4glc), t(gal beta 1----3galnac), i/ii(gal beta 1----3/4glcnac) and b(gal alpha 1- ...	2006	1525184
"raynaud's disease" in migraineurs: one entity or two?	two cases are reported of patients who were diagnosed as having both migraine and raynaud's disease. because they were able to achieve effective control of both headaches and extremity temperature after undergoing a comprehensive approach--utilizing medication, biofeedback, and psychotherapy--it is suggested that both conditions are manifestations of the same disorder. it is recommended that a first step in approaching concurrent diagnoses of this type involve combined treatment as is often used ...	2006	1446993
[treatment of stress urinary incontinence in women, by the raz technique. results].	the results achieved with the raz technique in 65 patients with stress urinary incontinence are presented. of these, 23 (35.4%) had mixed incontinence. overall, good results were achieved in 83.1%, defined as correction of incontinence and no micturition disorder. the present study emphasizes the importance of correct diagnosis for surgical indication. this technique is indicated for mixed urinary incontinence and coexisting cystocele or after previous failed antiincontinence surgery.	2006	1586218
genetic characterisation of the cjaab operon of campylobacter coli.	we investigated the regulation of the cjaa and cjab genes of campylobacter coli. these genes are seemingly arranged into one operon but appear to encode functionally different proteins i.e. an extracytoplasmic solute receptor and a mhs - metabolite: h+ symporter transport protein. analysis of various transcriptional cjaa and/or cjab lacz fusion constructs revealed that both genes are arranged in an operon. race analysis located the transcription start site of the cjaab operon 46 bp upstream of t ...	2006	17419285
late onset familial hallervorden-spatz disease: mr findings in two sisters.	two sisters affected by late onset hallervorden-spatz disease are described. in both patients, mr showed rings of decreased signal intensity surrounding hyperintense areas that gave a target-like appearance to the globi pallidi, a finding that corresponds with the known pathologic lesions in the disease. mr reflects the metabolic and anatomic evaluation of this disease.	2006	1595483
[clinico-morphological signs of different forms of destructive pancreatitis].	clinicomorphological comparisons in 434 cases of destructive pancreatitis showed that macroscopic signs of destruction develop in the first 12 hours from the onset of the attack. the elaborated criteria make it possible to evaluate the main morphological components of destructive pancreatitis--pancreonecrosis proper, parapancreatitis, peritonitis, and "polyvisceritis" and to use therapeutic measures on an individual basis.	2006	1779556
[percutaneous transluminal angioplasty in aortic coarctation. the short- and median-term results].	percutaneous transluminal angioplasty (pta) was performed in 34 patients with aortic coarctation (ao co). one of them with coarctation after surgical correction, the rest were native ao co. we used one balloon in 28 patients and two balloons simultaneously in 6. they were separated in three groups according to the degree of aortic arc hypoplasia. group i (mild to moderate hypoplasia n = 9) the gradient dropped 39% with angiographic improvement of 48% during the follow-up (m = 13.1 months). three ...	2006	1828657
[percutaneous transluminal angioplasty in aortic coarctation. the short- and median-term results].	percutaneous transluminal angioplasty (pta) was performed in 34 patients with aortic coarctation (ao co). one of them with coarctation after surgical correction, the rest were native ao co. we used one balloon in 28 patients and two balloons simultaneously in 6. they were separated in three groups according to the degree of aortic arc hypoplasia. group i (mild to moderate hypoplasia n = 9) the gradient dropped 39% with angiographic improvement of 48% during the follow-up (m = 13.1 months). three ...	2006	1828657
the application of mass spectrometry in the study of labile natural products.		2006	1794550
design a clinical information system.		2006	1392927
education in radiation oncology in europe.	the outcome of an inventory among 22 european countries with respect to the radiotherapy facilities and the training of new radiation oncologists in each country is described. the radiotherapeutic profession, which mostly prescribes also cytostatics or hormones, has become well-regulated in the last 20 years. most radiation oncologists are also involved in the diagnostic work-up and follow-up of the cancer patient. the numbers of radiotherapists and other staff, treatment capacities, and patient ...	2006	1447008
use of the polymerase chain reaction to isolate an s-locus glycoprotein cdna introgressed from brassica campestris into b. napus ssp. oleifera.	a self-incompatible canola-quality brassica napus ssp. oleifera line (w1) was generated by introgressing the s-locus from a self-incompatible b. campestris plant into the westar cultivar. using the polymerase chain reaction (pcr) with primers derived from conserved regions in s-locus glycoprotein (slg) alleles, the central region of the active slg gene (910) was obtained. the remaining portions of the cdna for this 910 gene were subsequently cloned using the pcr-rapid amplification of cdna ends ...	2006	1508146
sucralfate.		2006	1538733
[echography or urography in prostatic adenoma pathology].		2006	2426805
improving the preregistration period.		2006	1393214
mechanoreception by the endothelium: mediators and mechanisms of pressure- and flow-induced vascular responses.	mechanoreception, a widely distributed sensory modality, has been shown to be present in certain blood vessels. changes in physical forces, like sudden increase of transmural pressure or flow velocity (shear stress), trigger changes in blood vessel diameter; the former reduces it while the latter increases vessel caliber. these changes in diameter, which are the result of contraction and relaxation of vascular smooth muscle in the blood vessel media, can serve the purpose of physiological regula ...	2006	2242445
acute vincristine neurotoxicity.		2007	2859431
[problem of clinico-roentgenological diagnosis of acute pneumonia in infants in their first few months of life].	studies into the problems of diagnosing pneumonia in children of the first months of life carried out for many years have shown that pneumonia may be referred to the diseases with indefinite diagnostic criteria. in view of this fact the x-raying of the chest should be regarded as a method of varifying the diagnosis of pneumonia. the roentgenographic findings should be estimated bearing in mind the presence or lack of a syndrome such as bronchial obstruction and the epidemiological anamnesis data ...	2007	2075041
[an autopsy case of generalized seizures, myoclonus, blindness and deafness].	we have reported the clinical and autopsy findings in a case with generalized seizures, myoclonus, blindness and deafness which was accompanied by stroke-like episodes. this case was diagnosed as mitochondrial encephalomyopathy, lactic acidosis & stroke-like episodes (melas) from these findings. solitary and continuous lesions of softening were distributed in both hemispheres, more severely in the frontal and occipital poles. these lesions did not correspond to a vascular supply. the pulvinar, l ...	2007	2206639
[treatment of tissue loss in surgery of the scalp. an analysis of 89 patients brought to our attention].	the recent computerisation of operating theatre and forensic files facilitated a retrospective study of 136 plastic surgery operations performed on 89 patients presenting traumatic or surgical scalp tissue loss in the san camillo hospital, rome between 1/1/1980 and 31/12/1987. the study provided some useful data for the planning of the surgical approach to this delicate anatomical area. where the dimensions of the defect and the trophic condition of the local tissues permitted, the best function ...	2007	2771112
[treatment of tissue loss in surgery of the scalp. an analysis of 89 patients brought to our attention].	the recent computerisation of operating theatre and forensic files facilitated a retrospective study of 136 plastic surgery operations performed on 89 patients presenting traumatic or surgical scalp tissue loss in the san camillo hospital, rome between 1/1/1980 and 31/12/1987. the study provided some useful data for the planning of the surgical approach to this delicate anatomical area. where the dimensions of the defect and the trophic condition of the local tissues permitted, the best function ...	2007	2771112
conceptual approaches to avian navigation systems.	the general basis of migratory orientation in birds is most probably an endogenous time-and-direction programme. directions are selected with respect to celestial as well as geomagnetic clues. these clues appear to be integrated within a system that profits from the special advantages of either kind of environmental signal, and thereby can cope with their limitations. using these clues, and following a genetically determined intended direction (or sequence of directions) over a genetically deter ...	2007	1838512
regulation of alcohol consumption by the renin-angiotensin system: a review of recent findings and a possible mechanism of action.	the renin-angiotensin system has traditionally been associated with the regulation of fluid and electrolyte balance. in this review we summarize the data which ascribes a completely new function to this system, i.e., the regulation of alcohol consumption. in addition, we suggest a possible mechanism for this effect based on the concept of a satiety or stop process. the approach taken was to examine the effect on alcohol intake of a wide variety of drug, genetic, dietary, surgical and neurosurgic ...	2007	1852316
nucleotide sequence of the gyra gene of arcobacter species and characterization of human ciprofloxacin-resistant clinical isolates.	the nucleotide sequence of the gyra gene of arcobacter butzleri, arcobacter cryaerophilus, arcobacter cibarius, and arcobacter skirrowii was determined. the deduced gyra proteins are closely related to those of wolinella succinogenes and helicobacter pullorum, whereas those of campylobacter species showed less sequence identity. the phylogenetic analysis of gyra sequences provides a result similar to 16s rrna gene sequence phylogenetic analysis and allows the discrimination among a. butzleri spe ...	2007	17378897
growth yields in bacterial denitrification and nitrate ammonification.	denitrification and nitrate ammonification are considered the highest-energy-yielding respiration systems in anoxic environments after oxygen has been consumed. the corresponding free energy changes are 7 and 35% lower than that of aerobic respiration, respectively. growth yield determinations with pure cultures of paracoccus denitrificans and pseudomonas stutzeri revealed that far less energy is converted via atp into cell mass than expected from the above calculations. denitrification with for ...	2007	17209072
identification of disulfide reductases in campylobacterales: a bioinformatics investigation.	disulfide reductases of host-colonising bacteria are involved in the expression of virulence factors, resistance to drugs, and elimination of toxic compounds. large-scale genome analyses of 281 prokaryotes identified cxxc and cxxc-derived motifs in each microorganism. the total number of these motifs showed correlations with genome size and oxygen tolerance of the prokaryotes. specific bioinformatic analyses served to identify putative disulfide reductases in the campylobacterales campylobacter ...	2007	17588128
complete nucleotide sequence of the gyra gene of helicobacter pullorum and identification of a point mutation leading to ciprofloxacin resistance in poultry isolates.	to assess the molecular basis of nalidixic acid and ciprofloxacin resistance in helicobacter pullorum, the gyra gene of h. pullorum cip 104787t was sequenced. in addition, 9 isolates (2 susceptible to ciprofloxacin and resistant to nalidixic acid, 3 susceptible and 4 resistant to both antibiotics) were selected from 44 poultry isolates and the nucleotide sequences of their quinolone resistance-determining regions (qrdrs) were compared. the 2490 bp gyra gene showed an open reading frame encoding ...	2007	17644320
a pcr-dgge method for detection and identification of campylobacter, helicobacter, arcobacter and related epsilobacteria and its application to saliva samples from humans and domestic pets.	to develop a pcr-denaturing gradient gel electrophoresis (pcr-dgge) method for the detection and identification of campylobacter, helicobacter and arcobacter species (epsilobacteria) in clinical samples and evaluate its efficacy on saliva samples from humans and domestic pets.	2007	17916160
role of individual nap gene cluster products in napc-independent nitrate respiration of wolinella succinogenes.	bacterial nap gene clusters, encoding periplasmic nitrate reductase (napa), are complex and diverse, and the composition of the electron transport chain donating electrons to napa is poorly characterized in most organisms. exceptionally, wolinella succinogenes transfers electrons from formate via the menaquinone pool to napa independently of a membrane-bound c-type cytochrome of the napc family. the role of individual orfs of the w. succinogenes napaghbfld gene cluster is assessed here by charac ...	2007	17975082
the complete genome sequence and analysis of the epsilonproteobacterium arcobacter butzleri.	arcobacter butzleri is a member of the epsilon subdivision of the proteobacteria and a close taxonomic relative of established pathogens, such as campylobacter jejuni and helicobacter pylori. here we present the complete genome sequence of the human clinical isolate, a. butzleri strain rm4018.	2007	18159241
biochemical studies of klebsiella pneumoniae nifl reduction using reconstituted partial anaerobic respiratory chains of wolinella succinogenes.	in the diazotroph klebsiella pneumoniae the flavoprotein nifl inhibits the activity of the nif-specific transcriptional activator nifa in response to molecular oxygen and combined nitrogen. sequestration of reduced nifl to the cytoplasmic membrane under anaerobic and nitrogen-limited conditions impairs inhibition of cytoplasmic nifa by nifl. to analyze whether nifl is reduced by electrons directly derived from the reduced menaquinone pool, we studied nifl reduction using artificial membrane syst ...	2007	17329251
respiratory transformation of nitrous oxide (n2o) to dinitrogen by bacteria and archaea.	n2o is a potent greenhouse gas and stratospheric reactant that has been steadily on the rise since the beginning of industrialization. it is an obligatory inorganic metabolite of denitrifying bacteria, and some production of n2o is also found in nitrifying and methanotrophic bacteria. we focus this review on the respiratory aspect of n2o transformation catalysed by the multicopper enzyme nitrous oxide reductase (n2or) that provides the bacterial cell with an electron sink for anaerobic growth. t ...	2007	17027372
drug-drug interactions in hospital.	drug prescription charts of 200 randomly selected general medical patients in two dublin hospitals were examined for potential drug-drug interactions. using the stockly interaction alert, 37% of these patients had potential interactions but in only three was there clinical evidence that an interaction occurred. in an analysis of 150 spontaneous (yellow card) adverse drug reactions reports interactions contributed to only 8%. these results suggest that the importance of interactions as a cause of ...	2007	2045264
there should be more to life than medicine, author warns workaholic mds.		2007	1913416
inhibition by anti-cd2 monoclonal antibodies of anti-cd3-induced t cell-dependent b cell activation.	anti-cd3 mab can activate t cells to help in b cell activation as detected by late events, such as maturation of b cells into ig-secreting cells (igsc), or by early events, such as b cell surface expression of the activation marker cd23. two different anti-cd2 mab each inhibited anti-cd3-induced t cell-dependent b cell activation in a dose-dependent fashion. neither irradiation of the t cells prior to culture nor depletion of cd8+ cells abrogated the inhibitory effects of anti-cd2 mab. despite t ...	2007	1976440
wolinella succinogenes response to ox-bile stress.	the bacterium wolinella succinogenes is the only known species of its genus. it was first isolated from cow ruminal fluid, and in cattle, it dwells in the reticulum and rumen compartments of the stomach. the global protein response of w. succinogenes to ox-bile was investigated with the aim to understand bile-tolerance mechanisms of the bacterium. bacteria were grown in liquid media supplemented with different bile concentrations to determine its effects on growth and morphology. proteomic analy ...	2007	17375366
a dedicated haem lyase is required for the maturation of a novel bacterial cytochrome c with unconventional covalent haem binding.	in bacterial c-type cytochromes, the haem cofactor is covalently attached via two cysteine residues organized in a haem c-binding motif. here, a novel octa-haem c protein, mcca, is described that contains only seven conventional haem c-binding motifs (cxxch), in addition to several single cysteine residues and a conserved ch signature. mass spectrometric analysis of purified mcca from wolinella succinogenes suggests that two of the single cysteine residues are actually part of an unprecedented c ...	2007	17501927
c2 rotation and spinous process deviation in migraine: cause or effect or coincidence?	previous reports have shown an association between the side of c2 spinous process deviation or asymmetrical prominence, or vertebral rotation, and the side of the headache in unilateral migraine. however, this study has found that such c2 appearances were present as frequently in the controls as in the migraine patients, and that there was no association between the side of the anomaly and the lateralisation of the headache. the results were comparable for the different sub-groups of migraine.	2007	1780047
sexually transmitted diseases. gonorrhoeae.		2007	2223568
sexually transmitted diseases. gonorrhoeae.		2007	2223568
measuring cholesterol. a handbook for out-patient clinics and laboratory personnel.		2007	2100407
[stapling techniques in exeresis surgery of bronchogenic carcinoma].	from january 1983 to october 1989, 221 bronchogenic carcinomas were surgically treated at our department. different stapling techniques were employed in 153 cases: 138 stapled sutures of main and lobar bronchi, 33 stapled parenchymal sutures and 21 stapled sutures of the pulmonary artery. stapling-related complications were observed in 3 patients: 1 bronchopleural post-pneumonectomy fistula (0.72%); 2 persisting air leakages following stapled parenchymal suture (6%). the use of vascular staplers ...	2007	2223474
[stapling techniques in exeresis surgery of bronchogenic carcinoma].	from january 1983 to october 1989, 221 bronchogenic carcinomas were surgically treated at our department. different stapling techniques were employed in 153 cases: 138 stapled sutures of main and lobar bronchi, 33 stapled parenchymal sutures and 21 stapled sutures of the pulmonary artery. stapling-related complications were observed in 3 patients: 1 bronchopleural post-pneumonectomy fistula (0.72%); 2 persisting air leakages following stapled parenchymal suture (6%). the use of vascular staplers ...	2007	2223474
[fatal septum pellucidum cyst].	case history of a patient with cysta septi pellucidi is described. pathomechanism of the symptoms and that of the fatal outcome is curtly analysed. it is stated that communicating cysta may become non-communicating one and vice versa, so in case of a known cysta when neurologic symptoms appear, causal role of it has to be considered.	2008	2771394
[fatal septum pellucidum cyst].	case history of a patient with cysta septi pellucidi is described. pathomechanism of the symptoms and that of the fatal outcome is curtly analysed. it is stated that communicating cysta may become non-communicating one and vice versa, so in case of a known cysta when neurologic symptoms appear, causal role of it has to be considered.	2008	2771394
diagnosis of disseminated intravascular coagulation. role of d-dimer.	detection of the cross-linked fibrin degradation fragment, d-dimer, in patients at risk for disseminated intravascular coagulation (dic) is strong evidence for the diagnosis. d-dimer confirms that both thrombin generation and plasmin generation have occurred. patients at risk for dic (58) and normal controls (7) were studied. thirty-three patients had dic--with fragment d-dimer identified in their serum by immunoblotting. latex agglutination measurements of fibrin(ogen) degradation products (fdp ...	2008	2646905
diagnosis of disseminated intravascular coagulation. role of d-dimer.	detection of the cross-linked fibrin degradation fragment, d-dimer, in patients at risk for disseminated intravascular coagulation (dic) is strong evidence for the diagnosis. d-dimer confirms that both thrombin generation and plasmin generation have occurred. patients at risk for dic (58) and normal controls (7) were studied. thirty-three patients had dic--with fragment d-dimer identified in their serum by immunoblotting. latex agglutination measurements of fibrin(ogen) degradation products (fdp ...	2008	2646905
cord serum gamma glutamyltransferase in newborns.	this article reports correlations among gamma-glutamyltransferase (ggt), fetal haemoglobin (fh), alpha-fetoprotein, 5'-nucleotidase, ceruloplasmin, and direct, indirect, and total bilirubin in the serum of blood taken from the umbilical cords of 128 newborns delivered after 37-42 weeks of gestation. ggt was significantly correlated with alpha-fetoprotein, but not with direct bilirubin, indirect bilirubin, total bilirubin, fh, or %fh. neither fh nor %fh were correlated with alpha-fetoprotein, but ...	2008	2446803
regulation of lipoprotein lipid transfer by unesterified cholesterol.	elevated lipoprotein unesterified cholesterol altered differentially the transfer of cholesteryl esters and triacylglycerols. this resulted in increased mass transfer of cholesteryl esters from hdl to vldl coupled with an equimolar transfer of triacylglycerol from vldl to hdl.	2008	2654777
anticomplementary activity of dextran derivatives.	substitution with carboxylic and benzylamine sulphonated groups conferred on dextran both antithrombic activity and the capacity to inhibit formation of the amplification c3 convertase of complement. in dextrans substituted with carboxylic groups (greater than 40%), a high content of sulphonate (greater than 10%) resulted in both anticomplementary and antithrombic properties whereas a lower content of sulphonate resulted in high anticomplementary but weak antithrombic activity. the anticomplemen ...	2008	2578830
[postoperative hemopericardium compressing the left atrium. apropos of a case].	we report a case of tamponade due to an effusion of blood which had occurred two weeks after an aorto-coronary bypass and was unusually located behind the left atrium. the effusion, with severe clinical symptoms, was diagnosed by echocardiography and computerized tomography of the chest. these examinations provided an accurate anatomical diagnosis on which the approach route of the emergency operation was based.	2008	2494961
sensitivity of arterial baroreflex changes during daily activity.	1. continuous ambulatory arterial pressure monitoring was performed by telemetry in 34 hypertensive and four normotensive subjects and arterial baroreflex sensitivity was evaluated by computer analysis of pulse wave. three consecutive pulses were selected, on two criteria, from the 24 h recording: (i) progressive and linear increase or decrease in systolic arterial pressure and heart period, (ii) change of systolic arterial pressure in three pulses exceeds a threshold value. the systolic arteria ...	2008	2805440
binding and reduction of sulfite by cytochrome c nitrite reductase.	pentaheme cytochrome c nitrite reductase (ccnir) catalyzes the six-electron reduction of nitrite to ammonia as the final step in the dissimilatory pathway of nitrate ammonification. it has also been shown to reduce sulfite to sulfide, thus forming the only known link between the biogeochemical cycles of nitrogen and of sulfur. we have found the sulfite reductase activity of ccnir from wolinella succinogenes to be significantly smaller than its nitrite reductase activity but still several times h ...	2008	18201106
[errors and hazards of endoscopic procedures].		2008	2259108
variants of the tetrahaem cytochrome c quinol dehydrogenase nrfh characterize the menaquinol-binding site, the haem c-binding motifs and the transmembrane segment.	members of the napc/nrfh family are multihaem c-type cytochromes that exchange electrons with oxidoreductases situated at the outside of the cytoplasmic membrane or in the periplasmic space of many proteobacteria. they form a group of membrane-bound quinol dehydrogenases that are essential components of several electron transport chains, for example those of periplasmic nitrate respiration and respiratory nitrite ammonification. knowledge of the structure-function relationships of napc/nrfh prot ...	2008	18439144
characterization of the napgh quinol dehydrogenase complex involved in wolinella succinogenes nitrate respiration.	nitrate respiration catalysed by the epsilon-proteobacterium wolinella succinogenes relies on the napaghbfld system that comprises periplasmic nitrate reductase (napa) and various other nap proteins required for electron transport from menaquinol to napa or maturation of nap components. the w. succinogenes nap system is unusual as electron transfer to napa was shown previously to depend on both subunits of the predicted menaquinol dehydrogenase complex napgh but did not require a cytochrome c of ...	2008	18631238
electroneutral and electrogenic catalysis by dihaem-containing succinate:quinone oxidoreductases.	membrane protein complexes can support both the generation and utilization of a transmembrane electrochemical proton potential (deltap), either by supporting transmembrane electron transfer coupled to protolytic reactions on opposite sides of the membrane or by supporting transmembrane proton transfer. regarding the first mechanism, this has been unequivocally demonstrated to be operational for deltap-dependent catalysis of succinate oxidation by quinone in the case of the dihaem-containing sqr ...	2008	18793177
[clinical study of osteoporosis].		2008	2614196
[richter's syndrome with testicular localization].	based on a case showing testicular localisation of sarcomatous degeneration in the context of the progression of chronic lymphoid leukemia (richter's syndrome), the authors discuss the classification of intrascrotal lymphomatous conditions.	2008	2607173
iga nephritis associated with plasminogen abnormalities.	two patients with iga nephritis associated with hereditary plasminogen abnormalities are described. one patient had dysplasminogenemia and the other had plasminogen deficiency. in both patients, renal biopsy specimens showed significant arteriosclerotic changes in addition to mesangial proliferation. increased fibrinopeptide a concentration in their plasma suggested increased thrombin generation. in one patient, no systemic arteriosclerosis coexisted, judging from normal optic fundi and the abse ...	2008	2311307
growth in obese children treated for obesity.	this study assesses the growth patterns during a 5-year period in children aged 6 to 12 years treated for obesity using behavioral family-based treatment procedures. previous studies have suggested a decrease in height velocity after weight reduction, but these results did not consider either the height of the parent or the greater height of obese than nonobese children. results show that at entry, obese children are taller than their nonobese peers (74th percentile), and that even after 5 years ...	2008	2244623
the assertive community treatment worker: an emerging role and its implications for professional training.	assertive community treatment programs are designed to prevent the rehospitalization or homelessness of long-term mental health consumers and to improve their quality of life through the provision of intensive, "in vivo" help with everyday activities. the role of the assertive community treatment worker begins with the identification and engagement of appropriate consumers; proceeds to the development and implementation of practical intervention plans; includes home visiting, in-the-field skill ...	2008	2661400
perspectives in british and canadian neuro-psychopharmacology. proceedings of the british association for psychopharmacology and canadian college of neuro-psychopharmacology, joint annual meeting. 23-26 july, 1989, cambridge, england.		2008	2293246
the paraphilias and depo-provera: some medical, ethical and legal considerations.	paraphilic disorders are axis i psychiatric afflictions. they are not acquired by volitional decision, but are manifested by the association of erotic arousal with unacceptable behavior or stimulae (e.g., children). because paraphilic behavior occurs in the service of a biological drive, use of medication to suppress sexual appetite may constitute an adjunct in treatment. medroxyprogesterone can be used to decrease unacceptable erotic urges and fantasies, with the intent of increasing self-contr ...	2008	2529006
arm exercise training in the rehabilitation of patients with impaired ventricular function and heart failure.	although exercise training is an accepted part of comprehensive coronary care programs in patients with coronary artery disease, it still remains to be demonstrated whether or not exercise training should also be applied to patients with impaired ventricular function. circumstantial evidence exists that patients with impaired ventricular function may eventually benefit from an individually adapted exercise training program provided that contraindications for acceptance of cardiac patients to suc ...	2008	2397489
[selective conservatism in the management of abdominal stab wounds].	two hundred and two consecutive patients with abdominal stab wounds in a 14-year period were analysed as follows: (1) the patients were classified into 4 categories; type i (no peritoneal penetration) 12%, type iia (peritoneal penetration, no organ injury) plus type iib (organ injury, no repair required) 26% and type iii (organ injury, repair required) 62%. injuries caused by kitchen-knife or violence, wounds in the lower chest or epigastrium, and harakiri-injuries (japanese traditional method o ...	2008	2233667
evidence for compartmentation of high energy phosphagens in smooth muscle.	despite the lack of a clear understanding of the exact mechanisms involved, our results show that atp and pcr in the taenia do not distribute in a manner predicted by the equilibrium of the lohmann reaction in a single uniform compartment. our results may be of significance to the understanding of regulation of metabolism and its coordination with the various atp-dependent cellular functions. this may be particularly relevant to smooth muscle in which oxidative and glycolytic components of metab ...	2009	2678158
synthesis and investigation of effects of 2-[4- [[(arylamino)carbonyl]amino]phenoxy]-2-methylpropionic acids on the affinity of hemoglobin for oxygen: structure-activity relationships.	a series of 2-[4-[[[(substituted-phenyl)amino]carbonyl]amino]phenoxy]-2- methylpropionic acids and other substituted phenoxyacetic acids were synthesized and tested for their ability to reduce the affinity of hemoglobin for oxygen. 2-[4-[[[(3,4,5-trichlorophenyl)amino]carbonyl]amino]phenoxy]-2- methylpropionic acid was found to be the most potent compound known. structure-activity relationships of the compounds synthesized are discussed.	2009	2795607