Publications

some aspects of the epidemiology of equine grass sickness.		1974	4439627
[purine nucleotides of the brain and skeletal muscles of rats of different ages].		1974	4440323
[purine nucleotides of the brain and skeletal muscles of rats of different ages].		1974	4440323
plasma and pituitary msh levels in the rat after lesions of the hypothalamus.		1974	4449591
assessment of antibody-producing capacity in man.		1974	4449864
preclinical pharmacologic studies on 1-nitro-9-(dimethylamino)-acridine and 1-nitro-10-(dimethylaminoethyl)-9-acridone. i. acute and subacute action.		1974	4451445
on the hepatic pathology of fascioliasis in cattle and sheep.		1974	4453511
[preliminary studies of helminths and arthropods of gallus gallus domesticus from valdivia, chile (author's transl)].		1974	4455269
study of the ultimobranchial body of the chicken embryo in tissue culture.		1974	4464769
[changes in some enzyme activities of the rat heart, liver and kidney after administration of 5-ht. i].		1974	4464911
[skin resorptive action of diepoxy resins].		1974	4465183
[the effect of pituitary hormones on the bioelectrical activity of the gastric smooth muscle of small ruminants].		1974	4466679
[dynamics of certain indicators of nonspecific defense in patients with influenza].		1974	4468563
[innervation of the pelvic viscera in the sheep].		1974	4469280
[light and electron microscopic investigations of acrosome abnormalities in human spermatids and spermatozoa].		1974	4469548
glucosamine incorporation during the mitotic cycle of primary chicken fibroblast cells.		1974	4472124
a neuroblastoma times glioma hybrid cell line with morphine receptors.	a neuroblastoma x glioma hybrid cell line with well-developed neural properties was found that has high-affinity morphine receptors. the average cell contains approximately 3 x 10(6) receptors. in contrast, parent cells and other neuroblastoma or hybrid cell lines tested had few or no morphine receptors.	1974	4530316
[effect of hydrocortisone acetate on nutrition, hard tissue and dental caries in rats (author's transl)].		1974	4530468
["zone of intensified growth" in the developing mandible of the rat].		1974	4530502
[scanning electron microscope study on the removal of artificial dental plaque treated with a bacteriolytic enzyme from streptomyces globisporus--its synergistic effects with dextranase and lysozyme (author's transl)].		1974	4534639
[studies on enterovirus isolates using continuous cell lines. 1. experiments on the in vitro marker tests and plaque formation by poliovirus type 1 and echovirus type 6 strains (author's transl)].		1974	4377354
experimental infection of ancylostoma braziliense in dogs and cats in thailand ii. blood loss.		1974	4547205
suppressor cells in the rabbit appendix.		1974	4547314
tetragomphius melis n. sp. (nematoda; ancylostomidae) from the japanese badger, meles meles anakuma temminck.		1974	4547319
the kinectics of proliferation and maturation of mitogen-activated bone marrow-derived lymphocytes.		1974	4547710
effects of chemotherapy for prostatic carcinoma on t lymphocyte levels.		1974	4548092
stage-dependent changes in binding of iodinated fsh during ovarian follicle maturation in rats.		1974	4548403
kallikrein and kallikrein inhibitor in rats.		1974	4549598
identification and structural characterization of an inhibitor of catecholamine-induced free fatty acid mobilization from the calf midbrain.		1974	4549977
simultaneous microdetermination of homovanillic acid and 5-hydroxyindoleacetic acid in brain tissue using sephadex g-10 and qae-sephadex a-25.		1974	4549988
evidence for the action of d-lysergic acid diethylamide, mescaline and bufotenine on 5-hydroxytryptamine receptors in umbilical vasculature.		1974	4359552
drug-induced renal medullary necrosis. ii. mode of calcification in the kidney.		1974	4363123
drug-induced renal medullary necrosis. ii. mode of calcification in the kidney.		1974	4363123
effect of bicarbonate and phosphate on the adrenergic receptor response in human adipose tissue in vitro.		1974	4364370
[nuclease activity in the cultural fluid filtrate of actinomycetes--producers of antibiotics].		1974	4364596
proceedings: pituitary adrenocorticotrophic activity after adrenalectomy and adrenal enucleation in the rat.		1974	4365148
coronavirus infections in military recruits. three-year study with coronavirus strains oc43 and 229e.		1974	4365165
the turnover of cholesterol in human atherosclerotic arteries.	the equilibration of cholesterol between plasma and atherosclerotic arteries was studied in 13 patients with obstructive atherosclerosis 2-96 days after the intravenous and/or oral administration of isotopic cholesterol. arterial specimens were obtained in 12 patients during surgery for arterial reconstruction and in a 13th patient at autopsy. equilibration was calculated as the specific radioactivity of cholesterol in the arterial tissue relative to that in the plasma (percent).in specimens obt ...	1974	4367889
characterization of late polyoma mrna.	polyoma-infected mouse kidney cell cultures were labeled with [(3)h]uridine for 3 h late in the lytic cycle (26 to 29 h after infection) and rna was extracted from cytoplasm and nuclei and from isolated polyribosomes. sedimentation velocity analysis in sucrose gradients showed that polyoma-specific "giant" and 26s rnas are present exclusively in the nucleus. rna associated with cytoplasmic polyribosomes was analyzed by sedimentation in aqueous sucrose density gradients and dimethylsulfoxide sucr ...	1974	4367901
in vitro testosterone biosynthesis in the human fetal testis. ii. stimulation by cyclic amp and human chorionic gonadotropin (hcg).		1974	4372039
rapid in vivo assay for murine lymphatic leukaemia viruses.		1974	4372542
observations on the kidneys and urine of the wild norway rat, rattus norvegicus.		1974	4375334
the effect of bacterial collagenase upon healthy and burned skin of pigs in vitro.		1974	4375690
cell-mediated immune response in mice treated with steroidal contraceptives.	the splenomegaly assay (simonsen, 1962) was standardized using different strains of rats and mice. male wistar rat (donor)-female swiss mouse (host) was found to be the suitable combination that could be employed in subsequent experiments to study the potential of contraceptive steroids to alter cmir. the index of splenomegaly appeared to increase in case of mice treated with combination oral contraceptives (ovulen, ovral or enovid). the differences observed, however, neared significance only in ...	1975	55327
[androgen metabolism and leydig-cell function in acute and chronic liver disease (author's transl)].	diurnal variations of plasma testosterone and urinary excretion rates of testosterone-, androsterone-, aetiocholanolone-, and dha-glucuronide, as well as dha-sulphate were measured before and after selective leydig-cell stimulation (with 3 x 5000 iu human gonadotrophin) in eight patients with alcoholic liver cirrhosis, ten with acute hepatitis and four with haemochromatosis. the circadian variation of plasma testosterone and the maximal testosterone concentration after human gonadotrophin stimul ...	1975	127698
retinal neovascularization: the sleeping dog of the eye.		1975	127778
structural studies of heparitin sulfates.	heparitin sulfate fractions with a large range in sulfate content were subjected to degradation by flavobacterium heparinase and by nitrous acid. the products obtained were fractionated by chromatography, characterized, and used to arrive at tentative structures for these complex polysaccharides. the heparitin sulfate chains examined appear to be composed of: 1. uninterrupted blocks of n-acetylglucosamine containing disaccharides; 2. larger blocks with a molecular weight range of 5000 to 6000 wh ...	1975	123778
elementary particles in isolated rat liver and spleen nuclear membranes.	elementary spherical particles similar to those described in the mitochondria are found in isolated rat liver and spleen nuclear membranes. the particles are characterized by electron microscopy of sections and preparations negatively stained with phosphotungstic acid or with the atpase histochemical reaction product. the particles exhibit adenosine triphosphatase activity and have a mushroom-like shape with a sphere about 85-90 angstrom in diameter attached to inner face of the inner nuclear me ...	1975	126876
the possible role of tightly bound adenine nucleotides in oxidative and photosynthetic phosphorylation.	the tightly bound nucleotides of the beff-heart mitochondrial atpase are released during cold inactivation followed by ammonium sulfate precipitation. during incubation at 0 degrees c the sedimentation coefficient (s20w) of the atpase first declines from 12.1s to 9s. prolonged incubation or precipitation with ammonium sulfate leads to dissociation of the 9s component into subunits with s20w of 3.5s. the 9s component still bears bound nucleotides which exchange more extensively and rapidly with a ...	1975	127089
the biogenesis of mitochondrial membranes in the yeast saccharomyces cerevisiae.	membrane lipids of yeast mitochondria have been enriched by growing yeast cells in minimal medium supplemented with specific unsaturated fatty acids as the sole lipid supplement. using the activity of marker enzymes for the outer (kynurenine hydroxylase) and inner (cytochrome c oxidase and oligomycin-sensitive atpase) mitochondrial membranes, arrhenius plots have been constructed using both promitochondria and mitochondria obtained from o2-adapting cells in the presence of a second unsaturated f ...	1975	164216
bone changes in congenital cytomegalic inclusion disease.	1. while below 10 degrees c, the initial burst of pi liberation in the hydrolysis of mn(ii)-atp by heavy meromyosin or myosin subfragment 1 was inhibited by the pre-addition of adp without any change in the steady-state activity, it was not inhibited above 10 degrees c. the burst size was about one mole per two moles of myosin active sites. 2. above 10 degrees c, the ultraviolet absorption spectrum of heavy meromyosin induced by atp in mnc12 was similar to that induced in mgc12 and the spectral ...	1975	165786
cellular hypersensitivity to basic myelin (p2) protein in the guillain-barré syndrome.	lymphocytes of 29 subjects were assayed for mif production in response to p2 peripheral nerve protein, crude human peripheral nerve and human central nervous system al basic myelin protein. seven were performed in normal control subjects, 12 in guillain-barre patients (gb), 5 with other polyneuropathies and 5 in patients with multiple sclerosis (ms). only gb patients with acute illness produced mif in response to neuritogenic p2 protein and crude human nerve. two ms patients in the acute phase o ...	1975	165869
[mechanism of giant cell formation in rfl-cells with infection of murine leukemia virus (author's transl)].		1975	166032
[steroid hormones and liver tumors].		1975	166047
viral replication in human ovarian cell culture.	a method is presented for the preparation and maintenance of human ovarian cell cultures. sections of normal ovaries removed at surgery were minced, trypsinized, and seeded as cell cultures grown in minimal essential media at 37 c. long-term, low-passage cultures were grown in quantities sufficient to permit viral studies. ovarian cells, of passage 23, were challenged with 57 known viruses. of these viruses, 52 (especially viruses of the picornavirus and adenovirus groups) produced typical cytop ...	1975	168524
structural studies on two adenovirus 2-sv40 hybrids containing the entire sv40 genome.		1975	169085
[drug sensitivity of recently isolated bordetella pertussis and bordetella parapertussis].		1975	170435
effects of drugs and axotomy on acetylcholine levels in central cholinergic neurons.	administration of cholinergic nuscarinic agonists either did not alter, or increased hippocampal ach levels, while antagonists lowered the levels. as observed previously, placement of lesions in the medial septal area resulted in a rise in hippocampal ach levels in the first thirty minutes. agonist drugs administered immediately before lesion, further increased the post-lesion rise in ach levels. with antagonists, inconsistent results were obtained in that atropine blocked the post-lesion rise, ...	1975	172807
the relationship between prostaglandin release and lung c-amp levels during anaphylaxis in the guinea-pig.	a four-fold transient rise in c-amp levels was seen when sensitized guinea-pig lungs were challenged with antigen in vitro. this rise in c-amp also occurred in vivo and was shown to be due to release of prostaglandin e2. this conclusion is supported by the finding that inhibitors of prostaglandin synthesis (indomethacin and poly phloretin phosphate) prevent the rise in c-amp while neither ici 74, 917, an inhibitor of histamine release, nor antihistamines had any effect on the c-amp levels.	1975	172983
antibodies to herpesvirus hominis types 1 and 2 among women with neoplastic change of uterine cervix.	the occurrence of antibodies to herpesvirus hominis types 1 and 2 was studied in finland among patients with a neoplastic change of the uterine cervix. the following groups were studied: 220 patients with malignant or premalignant lesions of the uterine cervix, 143 control patients matched for age, socioeconomic level, marital status, home district and number of deliveries and 82 patients with breast or stomach cancer. antibodies to hvh types 1 and 2 were determined using the neutralization test ...	1975	173131
the cockerel as an animal model for atherosclerosis research.	the chicken is a good animal model for the study of atherosclerosis research because it is: 1. omnivorous. 2. small and suitable for prolonged laboratory investigation. 3. able to develop spontaneous atherosclerosis. 4. capable of producing atherosclerosis after cholesterol feeding with elevated hypercholesterolemia. a diet of 1/4% cholesterol plus 5% cottonseed oil added to starter-grower-mash resulted in aortic atherosclerosis with a slight but significant increase in plasma cholesterol. 5. pl ...	1975	173152
human erythrocyte galactokinase and galactose-1-phosphate uridylyltransferase: a population survey.	erythrocyte (rbc) galactokinase (galk) and galactose-1-phosphate uridylyl-transferase (galt) activities were measured in a random sample of 1,700 (1.082 black and 618 white) pregnant women from the philadelphia area to estimate the frequency of the genes galkg and galtg responsible for the two biochemically distinct forms of galactosemia. blacks have significantly lower mean rbc galk activities than whites (p less than .0005). the distribution of individual galk activities for blacks differs fro ...	1975	173184
[experimental investigations on the accumulation of radioactive compounds in autochtonal tumors in the rat (author's transl)].	for the first time results of investigations on rats with radioactive compounds in autochtonal tumors of the central nervous system, induced via placenta by ethyl-nitrose-urea (enu), are reported. in contrast to transplantation tumors the tumors induced by enu are comparable in regard to the szintigrafic results with human brain tumors. the radiopharmaceuticals 131i-hsa, 99mtc-pertechnetate, 203hg-chlormerodrin and 113m/111in-dtpa are similar to human brain tumors taken up by the enu-tumors. for ...	1975	173256
hemagglutinating properties of celo, an oncogenic avian adenovirus.	chicken-embryo-lethal-orphan (celo) virus, phelps strain, agglutinated erythrocytes at 37 c. the hemagglutinating activity, which is a function of complete and incomplete virus particles, was sensitive to heat but not to ph. the soluble components of the virus were similar in sedimentation characteristics to those obtained from human adenovirus type 1. the effects of chemical and physical agents on celo hemagglutinin, celo infectivity, and red-cell receptors suggested that the last were protein ...	1975	173279
inhibition of the binding of progesterone receptor to nuclei: effects of o-phenanthroline and rifamycin af/013.		1975	173315
effect of calcium on cyclic amp-dependent and cyclic gmp-dependent endogenous protein phosphorylation in mouse brain cytosol.		1975	173328
triiodothyronine binding proteins in rat liver cytosol.		1975	173337
[studies on the influence of anticoagulants on metastase formation of autochthonic hepatomas in the rat (author's transl)].	the frequency of metastases of malignant diethylnitrosamine-induced hepatomas and haemangioendotheliomas of the liver of female sprague-dawley rats (29%) was not influenced by application of acetyl-salicylic acid or phenprocoumon. likewise the anticoagulants did not alter tumor yields and induction periods.	1975	173350
proceedings: separation of the "estrogen-induced protein" from phosphoprotein phosphatase activity of immature rat uteri.	the distribution of phosphoprotein phosphatase (pppase) and estrogen-induced protein (ip) from 19- to 20-day-old rat uteri before and after fractionation of uterine cytosol, by ammonium sulfate, and by preparative cellulose acetate gel electrophoresis was studied. there was a lack of significant difference between the specific activity of pppase or its electrophoretic mobility in control extracts and those of extracts made 1 hour after injection of the rats with 5 mcg estradiol-17beta. most o ...	1975	173673
proceedings: repression of cholinesterase production in pseudomonas aeruginosa by nh4+ and glucose and its prevention by cyclic amp.		1975	173681
proceedings: pituitary plasma membrane-luteinizing hormone releasing hormone binding: evidence for the presence of specific binding sites in other tissues.		1975	173780
proceedings: studies on the receptors to the odoriferous steroid, 5alpha-androst-16-en-3-one, in sow nasal epithelium.		1975	173782
proceedings: the role of the locus coeruleus in the acquisition of a conditioned avoidance response.		1975	173834
response of c3h-avyfb female mice to a low oncogenic, milk-borne mammary tumor virus.	when low oncogenic milk-borne mammary tumor virus (mtv) of strain dd was tested in c3h-avyfb mice, as compared with the similar strain c3hfb, mammary tumors occurred with a higher incidence and at lower age in c3h-avyfbfdd (with dd-mtv) than in c3hfbfdd (with dd-mtv), as observed in virgin females. since the effect of breeding tended to mask any difference between the breeders, mammary tumor incidences were similar with a slightly higher age at tumor occurrence in the c3h-avyfbfdd females. thus ...	1975	173862
independent regulation of the nuclear and mitochondrial dna synthesis induced by either simian virus 40 or serum in mouse fibroblast 3t3 cells.	resting cultures of 3t3 cells (an established line of mouse fibroblasts) were released from density inhibition by either infection with simian virus 40 or addition of serum. the increased rate of thymidine incorporation into dna, induced by these two agents, was measured in the presence and in the absence of three inhibitory conditions (cycloheximide or dibutyryladenosine 3':5'-monophosphate added to the medium, or lack of anchorage). the inhibition was found to be quite similar in cultures stim ...	1975	173546
on the iron-sulfur cluster in hydrogenase from clostridium pasteurianum w5.	hydrogenase, purified to an average specific activity of 328 mumol of h2 evolved/(min x mg of protein) from clostridium pasteurianum w5, was found to have 4-5 fe and 4-5 labile sulfur atoms per molecule of 60,000 molecular weight, in contrast with earlier reports of 12 fe per molecule. displacement of the iron-sulfur cluster from hydrogenase by thiophenol in 80% hexamethyl phosphoramide:20% h2o yielded the fe4s4 (thiophenyl)4 dianion according to absorption spectroscopy. electron paramagnetic re ...	1975	174076
testing veterinary vaccines.		1975	174269
[sensitivity of cells of the transplanted sheep kidney line to foot-and-mouth disease virus].		1975	174273
[diagnosis of adenovirus infection in man using fitz-immunoglobulins to whole virion and to the purified hexone component (author's transl)].		1975	174329
[several properties of the recruiting response].		1975	174338
horizontally and vertically transmitted oncornaviruses of cats.		1975	174397
hormone and prostaglandin e1 control of potassium and cyclic amp levels in isolated rat liver cells.		1975	174402
hepatic metabolism of genetically diabetic (db/db) mice. i. carbohydrate metabolism.	hepatic carbohydrate metabolism in genetically diabetic mice (db/db) and their normal littermates has been studied. in db/db mice, body water was below normal and declined with age. the liver of db/db mice was abnormally large in relation to the metabolic mass of the body at all ages studied. in db/db mice, hepatic glycogenolysis, glycogen synthesis, glycogen synthetase, and phosphorylase were markedly increased. gluconeogenesis from alanine or lactate in perfused livers of db/db mice was greate ...	1975	174448
[bronchopulmonary aspergilloma in children and bronchogenic cyst. a new case].	the authors report a new case of aspergilloma developing in an intra-pulmonary bronchogenic cyst in a girl aged 10 years. a cure was obtained after surgical excision. the possibility of serious complications, such as hemoptysis, abscess formation and spread of the aspergillus, has two consequences; the first is the utility of regular supervision of any intra-pulmonary air cavity and, eventually, surgical removal. the second is the necessity of operation as soon as the diagnosis of aspergilloma h ...	1975	175446
[persistence of the foot-and-mouth disease virus in experimentally infected jackdaws].		1975	175553
[isolation and identification of autoimmune lipoprotein-antibody complex from blood serum of rabbits with experimental atherosclerosis].		1975	175569
[effect of hydrocortisone on lipid composition of blood serum lipoproteins in the development of experimental atherosclerosis].	single administration of hydrocortisone into rabbits with experimental atherosclerosis increased the content of atherogenous classes of lipoproteins (low density lipoproteins (ldl) and very low density lipoproteins (vldl) in the animals with distinct atheromatosis. content of the lipoproteins was decreased in animals, which had no atheromatous alterations in aorta under the effect of atherogenous diet. within 5 hrs after the single administration of hydrocortisone in rabbits with pronounced athe ...	1975	175572
proceedings: macrophage adenyl cyclase tachyphylaxis-a new property of migration inhibitory factor.		1975	176132
[restoration of the automatic contractile activity of k+-arrested heart muscle cells in culture by means of dibutyryl-3', 5'-adenosine monophosphate].	cultured myocardial cells of new-born rats which were arrested by 17.6-37.6 mm kcl regained their ability to contract spontaneously after perfusion with 8-10(-4)-4-10(-3) m dibutyryl cyclic amp. this adrenaline-like action of dbcamp is compatible with the notion that cyclic amp is involved as a second messenger in the action of cyclic amp-raising adrenergic agents on cardiac activity.	1975	176854
canine cyclic haematopoiesis: marrow transplantation between littermates.	dogs affected with cyclic haematopoiesis (ch) and experiencing recurrent 12-day cycles of neutropenia were supralethally irradiated and transplanted with marrow from their normal littermates. following transplantation of the normal marrow, dogs with ch experienced no further cycles of neutropenia. platelet and reticulocyte numbers also ceased to fluctuate cyclically in these dogs. the marrows of dogs with ch were transplanted into unaffected supralethally irradiated littermates. prompt engraftme ...	1975	127610
arthritis in the rabbit knee joint: a quantitated model.	the knee joint in rabbits has been used as an arthritis model for the study of acute immunologic injury. histologic examination of synovium plus a standardized procedure for irrigating inflammatory exudate from the joint allowed study of damage due to immune complexes, urate crystals, and arthus type vascular lesions by multiple parameters. with this model arthus lesions could be abolished with neutrophil depletion and reconstituted with intra-articular injection of neutrophil suspension. the ra ...	1975	128110
histoenzymatic changes in liver in acute poisoning with furfural.		1975	127937
cell number in human heart in atrophy, hypertrophy, and under the influence of cytostatics.	the dna content was determined in 30 human hearts from different age groups and of different weight classes. among these cases were included 4 hearts of children and 5 hearts of adults who had been treated with cytostatics. the total dna content was determined biochemically and the nuclear dna content was measured by means of feulgen cytophotometry. by combining both methods, the total number of heart muscle cells was determined. we obtained the following results: (1) the dna concentration remai ...	1975	128080
host response to implanted dacron grafts. a comparison between mesh and velour.	segments of open dacron mesh grafts were subcutaneously implanted in rats and harvested for a period of up to 12 weeks after operation at serial intervals. the gross and histologic events of the host response to the external surface were compared to that of segments of low-porosity dacron velour implanted in a similar fashion. mature collagen, generously vascularized with new capillaries, was noted throughout the mesh within three to four weeks, while a tightly bonded inner fibrous layer had for ...	1975	128337
effect of actinomyces viscosus on the establishment and symbiosis of streptococcus mutans and streptococcus sanguis in spf rats on different sucrose diets.		1975	123171
impaired 3h-testosterone uptake and metabolism in the accessory sex glands of diabetic castrated male rats.	the uptake and retention of 1,2-3h-testosterone in accessory sex glands, muscle and liver of streptozotocin diabetic castrated male rats, insulin-treated diabetic castrated rats and non-diabetic castrated control rats were studied at various time intervals after an intravenous injection. diabetes reduced the retention of 3h-testosterone in the prostate, the preputial gland and the epididymis. exogenous insulin slightly increased the retention of 3h-testosterone in these tissues of diabetic rats. ...	1975	130335
[solubilization of mg2+-dependent ca2+-activated atpase of brain microsome fraction].	mg2+-dependent ca2+-activated atpase (mg2+, ca2+-atp-ase) of microsome fraction from grey matter of great cerebral hemispheres of cattle is activated by 0.1% solution of digitonin. simultaneously 30-60% of initial fraction protein is extracted, respectively, with 0.1-0.3% concentrations of digitonin. the mg2+- and mg2+, ca2+-atpase activities manifest in solubilized protein. the maximal solubilization of both enzymes is reached when treating the fraction of brain microsomes with 0.3% solution of ...	1975	128176
evidence for 16alpha-hydroxylation of estrone 3-sulphate by guinea pig liver slices.	[6,7-3h,35s]estrone 3-sulfate (e13s) of 3h/35s = 3.57 was incubated with female guinea pig liver slices. small amounts of free steroid and estrone-3-glucuronide, each containing 3h, were found. in addition, e13s, 17beta-estradiol 3-sulfate, and a 'disulfate' fraction, with 3h/35s = 4.4, 4.3, and 4.7, respectively, were also isolated from the incubated tissue. the latter fraction was a major metabolite and about 45% of it consisted of 'disulfates' of 16alpha-hydroxyestrone and estriol, thus provi ...	1975	173453
renal adenylate cyclase-effects of diuretics.	the in vitro effect of various diuretics on rat kidney adenylate cyclase was investigated in crude homogenates of the cortex, the outer and inner medulla. 10-3 m furosemide inhibited adenylate cyclase by 40% in the cortex, by 16% in the outer medulla and by 43% in the inner medulla. 10-3 m ethacrynic acid inhibited adenylate cyclase activity by 65% in the cortex, 59% in the outer medulla and by 57% in the inner medulla. amiloride produced no significant inhibition of the adenylate cyclase reacti ...	1975	186272
effect of uv irradiation on transduction by coliphage t1.	lysates of the virulent coliphage t1 transduce seven markers between strains of escherichia coli with reproducilble efficiencies which range from 10(-7) to 10(-5). the ability of a uv-irradiated lysate to transduce arg(+), str(r), trp(+), lac(+), and pro(+) is 90% and bio(+) is 99% inactivated by doses which inactivate plaque formation of t1 by six orders of magnitude. a dose of irradiation which causes a 1- to 2-log drop in the titer of t1 stimulated gal(+) transduction by two- to three-fold; n ...	1975	1097732