Publications

[immunospecific demonstration of klebsiella capsules].		1968	4192274
further studies on serum protein formation by chimeras. i. effect of cytotoxic agents on serum protein formation.		1968	4176733
presence of two different immunoglobulin heavy chains in individual cells of established human hematopoietic cell lines.		1968	4177025
identification and evaluation of amitryptiline and its basic metabolites in rabbit's urine.		1968	4177068
the hong kong-68 influenza a2 variant.		1968	4177941
inhibition of brain sodium- and potassium-stimulated adenosine triphosphatase activity by chlorpromazine free radical.		1968	4235718
ultramicrochemical studies on the site of formation of dehydroepiandrosterone sulphate in the adrenal cortex.		1968	4235756
observations on the in vitro effect of quiniodochlor (5 chloro-7 iodo-8 hydroxyquinoline) on vibrio cholerae.		1968	4236129
[antistreptolysin o in mothers milk].		1968	4237445
[intestinal blood flow and absorption of drugs].		1968	4239215
studies on (na+-k+)-activated atpase. xx. properties of (na+-k+)-activated atpase in rat liver.		1968	4231299
[the relaxing effect of the sarcoplasmic reticulum under normal conditions and in experimental local tetanus].		1968	4248829
[changes in pharyngeal epithelium when cultivated in the organism].		1968	4248830
[effect of peracetic acid on ova of ascaris suis].		1968	4231702
nadh oxidase in blue-green algae.		1968	4300766
nadh oxidase in blue-green algae.		1968	4300766
embryotoxic activity of hypoglycin-a in the rat.		1968	4302634
morphological changes in the rat hypothalamus and adrenal cortex in the early postnatal period after acth and hydrocortisone administration, stress, and adrenalectomy.		1968	4302635
morphological changes in the hypothalamo-pituitary-adrenal system during early postnatal period in rats.		1968	4297498
[chemical study on inhibition of calcification].		1968	4309624
effect of polynucleotides on aminoacyl transfer ribonucleic acid synthetases. 3. inhibition of glutamyl transfer ribonucleic acid synthetase by natural polynucleotides.		1968	4299520
effect of polynucleotides on aminoacyl transfer ribonucleic acid synthetases. 3. inhibition of glutamyl transfer ribonucleic acid synthetase by natural polynucleotides.		1968	4299520
glucose-6-phosphatase activity of mouse pancreatic islets.		1968	4299799
[the study of the formation of lecithinase by clostridium perfringens type a].		1968	4300426
alterations in vitro of amino acid incorporating activity of liver preparations of non-starved normal and stress-induced rats.		1968	4300635
alterations in vitro of amino acid incorporating activity of liver preparations of non-starved normal and stress-induced rats.		1968	4300635
dynamics of immunomorphological changes in the organs of chickens after immunization with bpl vaccine and after challenge with fowl plague virus.		1968	4309689
dynamics of immunomorphological changes in the organs of chickens after immunization with bpl vaccine and after challenge with fowl plague virus.		1968	4309689
intrachain disulphide bridges in immunoglobulin g heavy chains. the fc fragment.	the disulphide bridges of the fc fragment (c-terminal half of the heavy chain) have been studied in several human immunoglobulins, containing heavy chains of different antigenic types (gamma1, gamma2, gamma3 and gamma4), and in heavy-chain-disease proteins. two intrachain disulphide bridges were found to be present. the sequences appear to be identical in the fc fragments of two types of chain studied (gamma1 and gamma3), and very similar to corresponding sequences of the fc fragment in rabbit. ...	1968	4889360
role of polynucleotide ligase in t4 dna replication.		1968	4877007
an indirect haemagglutination test for serum antibodies against mycoplasma pneumoniae using formalinized, tanned sheep erythrocytes.		1968	4878744
the changing epidemiology of rheumatic fever and acute glomerulonephritis.		1968	4883745
oxidation of sugars, other than glucose, by isolated mammalian islets of langerhans.		1968	4868055
use of tissue adhesives for arterial anastomoses.		1968	4868534
a simple procedure for detecting the presence of cyclopropane fatty acids in bacterial lipids.	four gram-negative bacterial species, including escherichia coli strain b, serratia marcescens, pseudomonas fluorescens, and vibrio cholerae (comma) strain nih 41, were investigated for fatty acid content by gas-liquid chromatography involving a preparatory technique which facilitated detection of cyclopropane fatty acids. methyl esters of fatty acids were subjected to mild catalytic hydrogenation to eliminate unsaturates. hydrogenation was followed by bromination which removed cyclopropane acid ...	1968	4869615
controlled comparison of tetracycline and furazolidone in cholera.	a controlled comparison of furazolidone and tetracycline in the treatment of cholera indicates that, in either dosage used, furazolidone reduced total stool volume by 50% and duration of diarrhoea by 40%. these results are comparable to those achieved with tetracycline, which was given in presently recommended dosage. both furazolidone and tetracycline significantly reduced the rate of stool output within 18 to 24 hours of starting antibiotic treatment. furazolidone was significantly less effect ...	1968	4873660
the field trial: some thoughts on the indispensable ordeal.		1968	4875751
reactions sequence of leucine activation catalysed by leucyl-rna synthetase. 2. formation of complexes between the enzyme and substrates.		1968	4871337
diagnostic laboratory medicine. leprosy.		1968	4917963
immediate and early functional adequacy of transplanted lungs.		1968	4887915
electron microscopy of particles associated with a bacteriocinogenic vibrio cholerae strain.		1968	5640388
fatty acids from vibrio cholerae lipids.		1968	5640986
site and characteristics of electrolyte loss and effect of intraluminal glucose in experimental canine cholera.	the site and characteristics of gastrointestinal electrolyte loss were investigated in eight dogs with experimental cholera induced by orogastric administration of 6-hr broth cultures of vibrio cholerae, strain ogawa 395. in these animals, all electrolyte losses originated in the small bowel, predominantly from the jejunum and ileum. the bicarbonate concentration of the small bowel fluid showed a progressive increase from duodenum, where it was less than that of plasma, to the terminal ileum, wh ...	1968	5645863
streptococcal sialidase. ii. kinetic and immunological studies of sialidase produced by group k streptococcus.	kinetic and immunological studies were carried out on the sialidase produced by strain 6646, group k streptococcus (k-sialidase). the k(m) values of k-sialidase were 0.9 mm for sialyllactose and 0.17 mm for bovine submaxillary mucin. the antibody against k-sialidase was produced in rabbits immunized with this enzyme. an assay procedure for determination of the anti-k-sialidase activity in terms of reciprocal of the serum dilution corresponding to the 50% inhibition point is described. anti-k-sia ...	1968	5650066
the in vitro activity of halquinol against vibrio cholerae.		1968	5657269
particulate nature of vibriocin: a bacteriocin from vibrio comma.		1968	5659626
in vitro production of choleragen and vascular permeability factor by vibrio cholerae.	the in vitro production of significant amounts of extracellular choleragen and vascular permeability factor (pf) by vibrio cholerae strain vc-12 (ogawa) in a basal peptone medium required forced aeration, low incubation temperature, and a low initial ph. filtrates of alkaline peptone cultures of vc-12 grown at 37 c contained an ion translocase inhibitory activity but neither choleragen nor pf activity, sterile filtrates of ph 6.5 peptone cultures of vc-12 grown at 29 c contained no ion transloca ...	1968	5663564
esterases and dna base composition analysis of vibrio cholerae and related vibrios.		1968	5698667
behaviour of an epidemic of vibrio cholerae el tor in gurgaon district, haryana state.		1968	5701286
some observations on vibrio cholerae.		1968	5701989
laboratory methods in cholera: isolation of vibrio cholerae (el tor and classical) on tcbs medium in minimally equipped laboratories.		1968	5707921
morphological changes of vibrio cholerae organisms in glucose saline.		1968	5709282
comparison of hemolysin, hemolysin-destructive factor and hemodigestive enzyme production by strains of vibrio cholerae and vibrio cholerae type el tor.		1968	5718716
cyclopropane fatty acids of rugose vibrio cholerae.		1968	5724978
effect of sodium lauryl sulphate on vibrio cholerae: turbidimetric and electron microscopic study.		1968	5732219
serological studies in cholera. i. vibrio agglutinin response of cholera patients determined by a microtechnique.	an agglutinin test for the determination of antibody responses to vibrio cholerae, requiring only 0.025 ml of serum, has been developed. this microtechnique permits the determination of agglutinin titres using fingertip blood, with results comparable with those obtained using venous blood taken at the same time.among 364 serum pairs in bacteriologically confirmed cases of cholera from an endemic area of east pakistan, the second serum sample being obtained 6 days or more after the onset of sympt ...	1968	5302302
serological studies in cholera. 2. the vibriocidal antibody response of cholera patients determined by a microtechnique.	a microtechnique is described for the determination of vibriocidal antibodies to vibrio cholerae, using 0.025 ml of fingertip blood or venous serum per test. this test could be used in epidemiological surveys, or as a routine test on patients admitted to hospital.fourfold or greater rises in vibriocidal titre were noted for 96.5% of 370 bacteriologically confirmed cholera patients in an endemic area of east pakistan (91.5% for the 94 children under 5 years in the study group). it is necessary to ...	1968	5302303
serological studies in cholera. 3. serum toxin neutralization--rise in titre in response to infection with vibrio cholerae, and the level in the "normal" population of east pakistan.	a method has been evaluated for the titration of antibodies to vibrio cholerae, based on the ability of sera containing such antibodies to neutralize the inflammatory effect of a factor from v. cholerae cultures on the skin of test animals.ninefold or greater rises in toxin-neutralization titre were found in 73% of 111 bacteriologically confirmed cholera patients in an endemic area of east pakistan, and in 2.5% of bacteriologically negative patients. this method compares well with the microtechn ...	1968	5302304
cholera vaccine field trials in east pakistan. 2. effectiveness in the field.	a cholera-vaccine field trial in a rural area of east pakistan where cholera is highly endemic has indicated that a high-potency whole-cell vaccine can provide significant protection against disease due to vibrio cholerae for at least 18 months. this vaccine gave more than 70% protection during the first cholera season after vaccination. in the second cholera season after the administration of a single dose of vaccine, protection fell in those under 5 years of age, while continuing at significan ...	1968	5302329
the relationship of vibriocidal antibody titre to susceptibility to cholera in family contacts of cholera patients.	a bacteriological and serological study of family contacts of 81 cholera patients was carried out in dacca, east pakistan. in the 10-day follow-up, 78 (16.7%) of 466 contacts were found to be infected with vibrio cholerae; half of them were symptomatic and 29 had to be admitted to hospital. a study of serum pairs revealed a 4-fold, or greater, rise in titre in 86% of those infected in whom diarrhoea was present, and in 77% of individuals with inapparent infections. the infection rate fell marked ...	1968	5303331
patterns of in vitro sensitivity in calcutta strains of vibrio cholerae.		1968	5306110
r-factors in calcutta strains of vibrio cholerae and members of the enterobacteriaceae.		1968	5306111
characterization of hemolysin and hemodigestive enzyme produced by strains of vibrio cholerae and vibrio cholerae type el tor.		1968	4975941
[diagnostic possibilities in a larva migrans visceralis infection, results on animal experiments].		1968	4976088
serological typing of mycobacteria for tracing possible sources of avian mycobacterial infections in man.	avian mycobacteria represent a potential danger to the human population in areas where effective control of tuberculosis has been achieved, but where tuberculosis is still present in poultry. during the period 1957-67, a total of 44 cases of pulmonary and non-pulmonary disease in man caused by avian mycobacteria were recorded in czechoslovakia. the source of infection was reliably established in only a small number of cases.the strains of bacteria isolated were, therefore, subjected to serologic ...	1968	4980761
effect of temperature and gas velocity on dry-heat destruction rate of bacterial spores.	spores of bacillus subtilis were dried in vacuo for use in dry-heat thermal destruction tests. survivor curve tests were conducted in a specifically designed dry-heat oven. this oven provided accurate temperature control and permitted air or nitrogen to be passed over the spores during the lethal treatment. experiments were carried out at various flow rates of the two gases (air and nitrogen) and various temperatures, and the data were expressed as survivor curves from which the decimal reductio ...	1968	4967069
interaction between human and simian adenoviruses in simian cells: complementation, phenotypic mixing and formation of monkey cell "adapted" virions.		1968	4969574
[hypocalcemic and hypophosphatemic action of thyrocalcitonin in fetal rats].		1968	4971541
cholera toxins: purification and preliminary characterization of ileal loop reactive type 2 toxin.	details for the preparation and partial purification of culture supernatant fluids of vibrio cholerae (v. comma) 569b which retain rabbit ileal loop fluid-accumulating activity are presented. these preparations were fractionated on sephadex g-200 and on diethylaminoethyl-sephadex. on the latter, two fractions were obtained by elution with a linear sodium chloride gradient. the fraction designated "fraction i" retains the toxic activity as demonstrated in the rabbit ileal loop model. chemical and ...	1968	4971885
toxic subunits of the crystal of bacillus thuringiensis.		1968	4973168
[studies towards the elimination of mycoplasma contaminations in cell cultures with the aid of antibiotics].		1968	4973924
[electromechanical dissociations. approach to a new physiopathologic concept: the excitation-contraction block].		1968	4974054
physiologically induced changes in the property of phenylalanine trna in escherichia coli.		1968	4941472
apha conference report, 1968. epidemiology.		1969	4974947
the velocity of the pulse wave distribution and arterial piesography in adult hamadryas baboons and rhesus monkeys.		1969	4981656
dissociation and reconstitution of 12-s toxin of clostridium botulinum type e.		1969	4983702
therapy of staphylococcal infections in monkeys. iv. further comparison of triacetyloleandomycin and erythromycins.	intravenous inoculation of a penicillin-resistant, phage type 80/81 staphylococcus caused lethal infection in 8 of 15 untreated monkeys. daily intragastric administration of 50 mg/kg of triacetyloleandomycin, erythromycin estolate, and erythromycin ethylsuccinate was followed by mortalities of 0 of 16, 3 of 16, and 3 of 10, respectively. at dose levels of 25 and 12.5 mg/kg, none of 7 and 4 of 7 receiving triacetyloleandomycin and erythromycin estolate, respectively, died, as compared to 3 of 4 d ...	1969	4984259
therapy of staphylococcal infections in monkeys. iv. further comparison of triacetyloleandomycin and erythromycins.	intravenous inoculation of a penicillin-resistant, phage type 80/81 staphylococcus caused lethal infection in 8 of 15 untreated monkeys. daily intragastric administration of 50 mg/kg of triacetyloleandomycin, erythromycin estolate, and erythromycin ethylsuccinate was followed by mortalities of 0 of 16, 3 of 16, and 3 of 10, respectively. at dose levels of 25 and 12.5 mg/kg, none of 7 and 4 of 7 receiving triacetyloleandomycin and erythromycin estolate, respectively, died, as compared to 3 of 4 d ...	1969	4984259
[symposium: functional structure of membrane system and protoplast].		1969	4985597
the influence of environment on the synthesis of magnesium-binding sites in bacillus subtilis var. niger cell walls.		1969	4977452
pathogenesis of experimental cholera. preparation and isolation of choleragen and choleragenoid.	choleragen, a diarrheagenic protein enterotoxin elaborated by vibrio cholerae, has been isolated from the supernate of fermenter cultures by steps involving ammonium sulfate precipitation, deae cellulose, sephadex g-75, and agarose a-5m chromatography. the resulting product appears to be pure according to immunoelectrophoretic, disc electrophoretic, ultracentrifugal, and immunologic criteria. sephadex gel filtration and membrane filtration studies suggest a molecular size of 61,000. the isolated ...	1969	4978880
direct haemagglutination by mycoplasma pneumoniae and its inhibition by immune serum.		1969	4980697
[septicemia with endocarditis caused by listeria monocytogenes in a 10-year-old biafran child].		1969	4994574
report of the 1966-67 cholera vaccine field trial in rural east pakistan. 2. results of the serological surveys in the study population--the relationship of case rate to antibody titre and an estimate of the inapparent infection rate with vibrio cholerae.	the 1966-67 cholera vaccine field trials in east pakistan tested 1- and 2-dose schedules of a commercial cholera vaccine in 40 000 children aged 3 months to 14 years. randomsample serological surveys, made prior to the inoculations and 3 months and 6 months after the inoculations, demonstrated that there was a rise in the vibriocidal titres of the vaccinated children during the first 3 months after inoculation and a subsequent fall by the end of the second 3 months. the antibody response to 2 do ...	1969	5306539
survival of vibrio cholerae in some of the waters of calcutta.		1969	5770842
disinfection of household articles contaminated with vibrio cholerae.		1969	5770843
some observations on vibrio cholerae.		1969	5771179
experimental canine cholera. ii. production by cell-free culture filtrates of vibrio cholerae.		1969	5776005
experimental canine cholera. iv. the chronic carrier state for vibrio cholerae.		1969	5776007
sialidase-like enzymes produced by group a, b, c, g, and l streptococci and by streptococcus sanguis.	a group of enzymes were prepared from the culture fluids of streptococci belonging to groups a, b, c, g, and l, and from a strain of streptococcus sanguis. these streptococcal enzymes (designated st-sialidases) released a substance shown to belong to the sialic acid group from the specific substrate bsm-st, a sialomucoid prepared from bovine submaxillary gland. they were inactive on n-acetylneuramin lactose prepared from bovine colustrum and on a sialomucoid prepared from bovine submaxillary muc ...	1969	5776530
neutralization of the vascular permeability factor of vibrio cholerae in man.		1969	5777737
agglutinating and bactericidal properties of fractions of rabbit anti-vibrio cholerae serum.	the major portion of the agglutinating and bactericidal activity of the sera of rabbits immunized with live vibrio cholerae or with cholera vaccine was found in the gammam fractions during the early stages of immunization. after 5 weeks or more, gammag fractions accounted for more than half of the agglutinating activity. when late antibody was measured as the amount of protein precipitated by somatic antigens, nearly 3 times as much gammag as gammam was required for agglutination, and about 30 t ...	1969	5788722
separation of type 2 toxins of vibrio cholerae.	choleragenic toxin was separated from vascular permeability factor by ion-exchange chromatography of supernatants of dialyzed peptone cultures of vibrio cholerae. the choleragenic toxin eluted from columns of qae-sephadex with low-ionicity systems is free of permeability factor activity. further elution of these columns with 0.5m nacl removes both the permeability factor and residual choleragenic toxin. when this latter material is chromatographed on columns of carboxymethyl-sephadex, the permea ...	1969	5804723
studies on the mode of action of streptomycin on vibrio cholerae and vibrio el tor.		1969	5824006
factors influencing in vitro skin permeability factor production by vibrio cholerae.	the development of a new semisynthetic medium which stimulates in vitro production of the skin permeability factor (pf) by vibrio cholerae is described. the effects of ph, aeration, temperature, and length of incubation on pf formation or release in strain 569b and several other strains, or both, are compared. data are presented which show that maximal pf accumulation occurs during a transitional period of growth joining the exponential and stationary phases of the growth cycle. pf elaboration i ...	1969	5344097
[2-deoxy-2,3-dehydrosialic acids. ii. competitive inhibition of vibrio cholerae neuraminidase by 2-deoxy-2,3-dehydro-n-acylneuraminic acids].		1969	5349377
reaction of vibrio cholerae and choleragenic toxin in ileal loop of laboratory animals.	accumulation of fluid in the ligated ileal loop upon injection of cholera vibrios or choleragenic toxin seems to be a generalized phenomenon in laboratory animals.	1969	5359618
fine structure of vibrio cholerae during toxin production.	the fine structural changes associated with cell growth and toxin production have been examined in vibrio cholerae strain 569b. no morphological alterations in the cell envelope are apparent during logarithmic growth with thin-section techniques. however, internal swelling, suggesting alteration of cell envelope permeability, is evident particularly during the late logarithmic and early stationary phases of growth. certain extracellular material demonstrable with negative-stain techniques does a ...	1969	5361220
somatic o antigen relationship of brucella and vibrio cholerae.	the antigenic relationship between brucella species and vibrio cholerae was examined by agglutinin and agglutinin-absorption tests by using rabbit antisera. brucella antisera agglutinated only the inaba serotype of v. cholerae and at low titer. inaba-reactive antibody was absorbed by either heat-stable (100 c, 2 hr) ogawa or inaba o antigens. cholera antisera from rabbits immunized with either o or ho antigens of either ogawa or inaba serotypes contained brucella agglutinins. this activity was a ...	1969	5370272
progressive changes of vibrio serotypes in germ-free mice infected with vibrio cholerae.	germ-free mice inoculated with vibrio cholerae became colonized with vibrios throughout the gastrointestinal tract, but they did not become ill. high vibrio concentrations in the feces were observed throughout the 3 months of observation in spite of the presence of serum antibody. reciprocal conversions of both inaba and ogawa serotypes occurred regularly after inoculation and could be correlated temporally with the appearance of serum-agglutinating antibody. both of these smooth serotype were l ...	1969	5370274