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primary colonic lymphoma.the colon is a rare location for gastrointestinal non-hodgkin's lymphoma (nhl). this study was undertaken to identify risk factors, presentation, treatment, and prognosis for primary colonic lymphoma (pcl) through review of a large tertiary care hospital system experience.200010962456
a study to determine the incidence and prevalence of newly discovered human immunodeficiency virus infection during the prenatal care period.this study asked the following questions: 1) does hiv testing in pregnancy identify women who previously were not known to be hiv positive? 2) when in pregnancy are women identified as hiv infected? 3) does hiv seroconversion occur during the prenatal care period?200010968601
the gene machine. 200011004901
a physician's guide to the human genome. 200011004902
use of a repetitive dna probe to type clinical and environmental isolates of aspergillus flavus from a cluster of cutaneous infections in a neonatal intensive care unit.aspergillus flavus is second to a. fumigatus as a cause of invasive aspergillosis, but no standard method exists for molecular typing of strains from human sources. a repetitive dna sequence cloned from a. flavus and subcloned into a puc19 vector, paf28, was used to type 18 isolates from diverse clinical, environmental, and geographic sources. the restriction fragment length polymorphisms generated with ecori- or psti-digested genomic dna and probed with digoxigenin-labeled paf28 revealed comple ...200011015372
molecular scanning for mutations in the insulin receptor substrate-1 (irs-1) gene in mexican americans with type 2 diabetes mellitus.insulin receptor substrate-1 (irs-1) is an endogenous substrate for the insulin receptor tyrosine kinase, which plays an important role in insulin signaling. mutations in the irs-1 gene are associated in some populations with obesity and type 2 diabetes.200011025561
economic evaluation of safer choices: a school-based human immunodeficiency virus, other sexually transmitted diseases, and pregnancy prevention program.to evaluate the cost-effectiveness and cost benefit of safer choices, a school-based human immunodeficiency virus, other sexually transmitted diseases, and unintended pregnancy prevention intervention for high school students.200011030854
proxy measures and human immunodeficiency virus care. 200011031378
prevalence of sexually transmitted infections and associated risk factors among populations of drug abusers.a cross-sectional survey was conducted of sexually transmitted diseases (stds) and risky behaviors among 407 drug abusers in treatment facilities in 1998. infections with human immunodeficiency virus (hiv), hepatitis b virus (hbv), hepatitis c virus (hcv), herpes simplex virus type 2 (hsv-2), and syphilis were detected by testing serum antibody levels; chlamydia and gonorrhea were detected by testing nucleic acid levels in urine. logistic regression analysis was performed to measure associations ...200011049771
the use of digital photography to support a medical mission to honduras.the south texas physicians outreach (stpo) organization makes at least one annual mission to santa rosa de copan, honduras to provide much needed medical and surgical care to the residents of western honduras. the author was named the team photographer for both a trip in 1998 and a subsequent visit in 1999. in preparing for the 1999 trip, a plan to reduce the expenditure by stpo for photography support was put into motion. it was decided that digital photography would eliminate most of the cost ...200011050711
patient safety in america: comparison and analysis of national and texas patient safety research.the institute of medicine (iom) report on patient safety in late 1999, to err is human, attracted great national attention when it announced that 44,000 to 98,000 patients die each year in american hospitals because of patient safety problems and that a patient safety crisis exists in american health care and american hospitals. the report relied heavily on a harvard group's study of hospital care in new york in 1984 and another harvard group's study of hospital care in utah and colorado in 1992 ...200011070738
st louis encephalitis: a review of 11 cases in a 1995 dallas, tex, epidemic.to update some of the clinical features of st louis encephalitis (sle), a common arboviral infection that occurs in epidemic patterns in the south-central and midwestern united states.200010634457
to err is human: iom report implications. 200011949092
the phylogenetics of mycotoxin and sclerotium production in aspergillus flavus and aspergillus oryzae.aspergillus flavus is a common filamentous fungus that produces aflatoxins and presents a major threat to agriculture and human health. previous phylogenetic studies of a. flavus have shown that it consists of two subgroups, called groups i and ii, and morphological studies indicated that it consists of two morphological groups based on sclerotium size, called "s" and "l." the industrially important non-aflatoxin-producing fungus a. oryzae is nested within group i. three different gene regions, ...200011273679
visceral leishmaniasis in a dog from maryland.visceral leishmaniasis is a zoonotic disease that can be transmitted from dogs to humans by a sand-fly vector. endemic cases of visceral leishmaniasis among dogs in oklahoma, texas, and ohio have been reported. recent reports of visceral leishmaniasis in foxhounds in the eastern coastal states has raised new concerns about the importance of this disease in the united states.200011110461
friends and pets as companions: strategies for coping with loneliness among homeless youth.loneliness and negative health outcomes associated with being homeless and living on the streets.200011111505
rabies surveillance in the united states during 1999.during 1999, 49 states, the district of columbia, and puerto rico reported 7,067 cases of rabies in nonhuman animals to the centers for disease control and prevention, a decrease of 11.2% from 7,961 cases in nonhuman animals and 1 case in a human being reported in 1998. more than 91% (6,466 cases) were in wild animals, whereas 8.5% (601 cases) were in domestic species (compared with 92.4% in wild animals and 7.6% in domestic species in 1998). no cases of rabies were reported in human beings in 1 ...200011132881
it wasn't about race. or was it?hope barrows, a partner at the national accounting firm fuller fenton, drove to the office on sunday and swiped her access card to enter the parking garage. she noticed that another car followed her in--without using an access card. hope could see that the driver was a man, but she didn't recognize him. concerned for her safety, she got out and asked to see his id. dillon johnson, an associate at the same firm, was rushing to meet a colleague to review a client's file. seeing the garage door was ...200011143153
influenza a in a basic training population: implications for directly observed therapy.to describe our evaluation of basic trainees exposed to influenza a and our experience with mass prophylaxis.200011149067
prevention of acute otitis media by prophylaxis and treatment of influenza virus infections.human experimental challenge studies with influenza virus infection and controlled intervention trials have demonstrated beyond doubt the role of influenza virus infection in the pathogenesis of acute otitis media. influenza virus infections not only disrupt eustachian tube function, but also impair recovery from infection and facilitate attachment of bacterial pathogens to respiratory epithelial cells. immunization of young children with either inactivated or live, attenuated influenza vaccine ...200011163464
vitamin k deficiency. the waterbirth and hospitalization of amanda. 200011984900
ethical issues in migrant farmworker studies. 200012542044
combination of antibodies shown to block transmission of hiv-like virus across mucous membranes. vertical transmission.researchers at the dana-farber cancer institute suggest the use of combined antibodies to block transmission of hiv-like virus across the mucous membranes. this passive immunization, wherein a combination of 3 potent human antibodies is administered shortly before delivery and after birth, aims to reduce the transmission of the virus. this method was first tested on monkeys who were exposed to a virus containing parts of the human and monkey aids viruses. it was observed that throughout the 6 ...200012295706
physicians' attitudes toward pain and the use of opioid analgesics: results of a survey from the texas cancer pain initiative.despite extensive progress in the scientific understanding of pain in humans, serious mismanagement and undermedication in treating acute and chronic pain is a continuing problem. this study was designed to examine the barriers to adequate pain management, especially as they might be associated with community size and medical discipline.200010832945
josiah gordon "doc" scurlock: physician, gunfighter, and family man. 200016808056
a comparative assessment of contaminants in fish from four resacas of the texas, usa-tamaulipas, mexico border region.a recent survey of contaminant information for the lower rio grande valley (lrgv), texas, has shown that little is known about contaminants and their impacts on biota of resacas (oxbows) along the us-mexico border. in 1996, fish were collected from four resacas in the texas-tamaulipas border region to assess contaminant loadings and their impacts on fish and birds. tissue residue concentrations in fish were analyzed and also compared to two histopathological bioindicators of unhealthy environmen ...200111488385
a collaborative program between a school of public health and a local health department to increase hiv testing of pregnant women.this study evaluates the effectiveness of a continuing medical education (cme) program that sought to increase hiv testing of women attending maternity clinics of the city of houston department of health and human services (hdhhs). the cme program consisted of 14 training sessions given in 1995, 1996, 1997, 1999, and 2000. educational objectives included increasing patient knowledge of hiv perinatal testing, increasing patient appreciation of the importance of hiv testing, and developing staff s ...200112196618
low-income minority women at risk for cervical cancer: a process to improve adherence to follow-up recommendations.the houston department of health and human services (hdhhs) has a centralized process for notifying and setting up follow-up appointments for women with abnormal pap smears who are clients of hdhhs health centers. faculty and a student from the university of texas school of public health and hdhhs personnel jointly conducted a study to evaluate the process and performance of the system.200112196621
hla-restricted cd8+ cytotoxic t lymphocyte, interferon-gamma, and interleukin-4 responses to respiratory syncytial virus infection in infants and children.cd8+ cytotoxic t lymphocyte (ctl) activity, interferon (ifn)-gamma, and interleukin (il)-4 production were evaluated in a blinded manner among respiratory syncytial virus (rsv)-infected newborns and their mothers for 3 epidemic seasons. most mothers (80%) exhibited rsv-specific cd8+ ctl activity. twenty (80%) of the 26 infants exhibited significant rsv-specific ctl activity during or after their first rsv season. ctl frequency increased with rsv infection rate, reaching 75% by the end of the thi ...200111181144
implementation of a screening program for chlamydial infection in incarcerated adolescents.in collaboration with the houston department of health and human services, the authors implemented and evaluated a urine-based chlamydia screening program in incarcerated youth in harris county, texas, and assessed predictor variables for infection.200111196046
concerns of pregnant women about bing tested for hiv: a study in a predominately mexican-american population.more than 90% of pediatric acquired immune deficiency syndrome (aids) cases are due to mother-to-child (vertical) transmission. medical intervention can reduce the risk of vertical transmission human immunodeficiency virus (hiv) from 25% to less than 8%. however, studies have suggested that approximately one-fourth of women may refuse hiv testing as part of routine prenatal care. the purpose of this study was to identify concerns that pregnant women might have that would impact their decision to ...200111224934
prevalence of antibodies to sin nombre virus in humans living in rural areas of southern new mexico and western texas. 200111226584
characterization of a novel autosomal dominant bleeding disorder in a large kindred from east texas.a large east texas family with autosomal dominant inheritance of a novel bleeding disorder has been identified. the disorder is characterized clinically by easy bruising, life-threatening bleeding with trauma or surgery, and menorrhagia in affected women. laboratory studies demonstrated prolongation of the prothrombin time and activated partial thromboplastin time in affected individuals. paradoxically, assays of known coagulation factors are all within normal limits. to determine the molecular ...200111238089
gross anatomy course content and teaching methodology in allied health: clinicians' experiences and recommendations.the purpose of this study was to sample the experiences and recommendations of clinicians in allied health fields about gross anatomy courses. the objective was to determine if practicing clinicians recommended a course in gross anatomy, and, if so, their recommendations for course content and teaching methodology. questionnaires were mailed to a random selection of occupational therapists (ots), physician assistants (pas), and physical therapists (pts) licensed in the state of texas. in additio ...200111241751
health professional students' occupational exposures to blood-borne pathogens: primary and secondary prevention strategies.health science students, along with the health professionals they hope to become, are at increased risk for certain occupational injuries and illnesses. one of these risks is occupational exposure to blood-borne pathogens, such as human immunodeficiency virus (hiv) and hepatitis, which may result in severe illnesses or even death. two case studies demonstrate postexposure care of exposed individuals at the university of texas medical branch student health services before and after policy changes ...200111272627
a major locus for fasting insulin concentrations and insulin resistance on chromosome 6q with strong pleiotropic effects on obesity-related phenotypes in nondiabetic mexican americans.insulin resistance and hyperinsulinemia are strong correlates of obesity and type 2 diabetes, but little is known about their genetic determinants. using data on nondiabetics from mexican american families and a multipoint linkage approach, we scanned the genome and identified a major locus near marker d6s403 for fasting "true" insulin levels (lod score 4.1, empirical p<.0001), which do not crossreact with insulin precursors. insulin resistance, as assessed by the homeostasis model using fasting ...200111283790
encephalopathy associated with respiratory syncytial virus bronchiolitis.respiratory syncytial virus is an extremely common cause of childhood respiratory infections resulting in significant morbidity and mortality. although apnea is a well-known complication in young infants with respiratory syncytial virus bronchiolitis, the encephalopathy associated with this infection is not well recognized. our study reveals an incidence of encephalopathy of 1.8% in a total of 487 patients with respiratory syncytial virus bronchiolitis studied over a period of almost 4 years. se ...200111292214
a molecular analysis of dietary diversity for three archaic native americans.dna was extracted from three fecal samples, more than 2,000 years old, from hinds cave, texas. amplification of human mtdna sequences showed their affiliation with contemporary native americans, while sequences from pronghorn antelope, bighorn sheep, and cottontail rabbit allowed these animals to be identified as part of the diet of these individuals. furthermore, amplification of chloroplast dna sequences identified eight different plants as dietary elements. these archaic humans consumed 2-4 d ...200111296282
systemic sclerosis in 3 us ethnic groups: a comparison of clinical, sociodemographic, serologic, and immunogenetic determinants.to determine whether ethnic factors influence the presentation, serologic expression and immunogenetics of systemic sclerosis (ssc), patients from 3 ethnic groups were compared for clinical features, ssc-associated autoantibodies, and human leukocyte antigen (hla) class ii alleles.200111303306
development and assignment of bovine-specific pcr systems for the texas nomenclature marker genes and isolation of homologous bac probes.in 1996, popescu et al. published the texas standard nomenclature of the bovine karyotype in which 31 marker genes, already mapped in man, were chosen to permit unambiguous identification and numbering of each bovine chromosome. however, specific pcr systems were not available for each marker gene thus preventing the assignment of part of these markers by somatic cell hybrid analysis. in addition, some difficulties remained with the nomenclature of bta25, bta27 and bta29. in this work, specific ...200111333834
passive ozone network of dallas: a modeling opportunity with community involvement. 1.despite tremendous efforts toward regulating and controlling tropospheric ozone (o3) formation, a large portion of the u.s. population presently lives in environments where air quality exceeds both 1- and 8-h national ambient air quality standards (naaqs) set for o3. high o3 concentrations annually cost the united states billions of dollars in excessive human health costs, reduced crop yields, and ecological damage. this paper describes a regional networking of o3 monitoring sites, operated by t ...200111351526
texas man pleads guilty to using hiv as a deadly weapon. 200111668829
molecular characterization of a novel recombinant strain of human astrovirus associated with gastroenteritis in children.we report a naturally occurring human astrovirus (hastv) strain detected in two different geographic locations. we identified two isolates of this strain in a diarrhea outbreak at a child care center in houston, texas; and two isolates in diarrhea stool samples from two children in mexico city. all four isolates were detected in stool samples by enzyme immunoassay (eia). one of the mexican isolates was typed by eia and all four isolates were hastv-5 by typing rt-pcr. the four isolates were >97% ...200111811685
exploring large employers' and small employers' knowledge, attitudes, and practices on breastfeeding support in the workplace.human resource professionals from different industries participated in focus groups in austin, texas. from a social marketing perspective, employers' knowledge, attitudes, and practices in providing breastfeeding support for lactating employees were explored. employers knew about the benefits of breastfeeding for mothers and children. however, they did not place a high priority on providing breastfeeding support. employers identified the barriers to and motivators for providing breastfeeding sup ...200111847850
passive ozone network of dallas: a modeling opportunity with community involvement. 2.attaining the current lower tropospheric u.s. ozone standards continues to be a difficult task for many areas in the u.s. concentrations of ozone above the standards negatively affects human health, agricultural crops, forests, and other ecosystem elements. this paper describes year two (1999) of a regional networking of passive and continuous ozone monitoring sites in the dallas-fort worth (dfw) metroplex region. the objectives of the second year of study were to (1) validate conclusions of the ...200111757597
complying with the health insurance portability and accountability act. privacy standards.the privacy rule: limits the use and disclosure of phi to purposes of treatment, payment, or routine health care operations. requires covered entities to provide advance notice to the public of its policy governing disclosure of phi. requires entities covered by the standard to secure general client consent to use and to disclose phi for treatment, payment, or routine health care operations and to obtain specific client authorization to use or to disclose phi for all other purposes unless the di ...200111760704
no more on-time delivery. 200111762089
texas medicine. rounds. hhs to fund ut-san antonio research on u.s.-mexico border health care. 200111767460
rabies surveillance in the united states during 2000.during 2000, 49 states, the district of columbia, and puerto rico reported 7,364 cases of rabies in nonhuman animals and 5 cases in human beings to the centers for disease control and prevention, an increase of 4.3% from 7,067 cases in nonhuman animals reported in 1999. ninety-three percent (6,855 cases) were in wild animals, whereas 6.9% (509 cases) were in domestic species (compared wth 91.5% in wild animals and 8.5% in domestic species in 1999). compared with cases reported in 1999, the numbe ...200111767918
an internet database of crotaline venom found in the united states.many snake venoms have been shown to be complex mixtures of pharmacologically important molecules, some of which have potential therapeutic value in the treatment of clot-induced ischemia, cancer and other human disorders. the literature contains many references on how venom and/or venom components are being used in medicine. within the united states, there are 44 subspecies of poisonous snakes. despite this rather vast diversity, 90% of the venom-related biomedical research conducted on native ...200111072040
distinct distribution of rare us genotypes of kaposi's sarcoma-associated herpesvirus (kshv) in south texas: implications for kshv epidemiology.genotypes of kaposi's sarcoma (ks)-associated herpesvirus (kshv) from patients with ks in south texas were examined. open-reading frame (orf)-k1 and orf-k15 dna segments from 16 kshv isolates were amplified by polymerase chain reaction, and kshv subtypes were assigned on the basis of sequence variations. k1 genotyping showed that 75% exhibited c subtype and 25% exhibited a subtype. k15 genotyping showed that 56% exhibited m form, of which 89% exhibited c3 k1 subtype and 44% exhibited p form. a u ...200111106539
prevalence of sparganosis by county of origin in florida feral swine.sparganosis is a parasitic infection in amphibians, reptiles and mammals including feral swine and man. it is caused by migration of the metacestode (spargana) of spirometra. the primary objective of this study was the determination of the prevalence of gross sparganosis in florida county of origin in slaughtered feral swine. tracebacks to county of origin were conducted for florida feral swine with and without gross sparganosis. feral swine trapped in florida and presented for slaughter in a te ...200111390076
prevalence of neuroendocrine dysfunction in patients recovering from traumatic brain injury.although hypopituitarism is a known complication of head injury, it may be underrecognized due to its subtle clinical manifestations. the nonspecific symptoms may be masked by and may contribute to the physical and psychological sequelae of brain trauma. this study examines the prevalence of neuroendocrine abnormalities in patients rehabilitating from traumatic brain injury. seventy adults (mean age, 31.5 +/- 1.1 yr; range, 18--58; 46 men and 24 women) with traumatic brain injury an average of 4 ...200111397882
ethical issues in community-based cancer control: considerations in designing interventions.intervention studies are essential in the drive to reduce the burden of cancer in the united states. the means to accomplish primary and secondary cancer prevention is possible through health education focused on smoking, dietary changes, and the judicious application of screening technologies. the goal is to demonstrate these can work in the "real world" of the community workplace. the challenge of designing and conducting effective studies must include practical solutions to ethical as well as ...200111401624
water hardness and sodium trends in texas aquifers.median hardness and sodium levels in groundwater were calculated for 244 texas counties from measurements at 7728 water wells. the data were mapped and analyzed with a geographic information system (gis). county median hardness levels varied widely, from 4-2304 mg l-1. more than 60% of the counties had hardness medians above 180 mg l-1. county medium sodium concentrations ranged from 6-1170 mg l-1, with more than 90% of those values exceeding 20 mg l-1. there was a significant positive correlati ...200111411143
hepatitis c virus infection-related morbidity and mortality among patients with human immunodeficiency virus infection.hepatitis c virus (hcv) has emerged as a major pathogen among patients with human immunodeficiency virus (hiv). morbidity and mortality were compared among 263 patients with hiv alone, 166 patients with hiv and hcv, and 60 patients with hcv alone (mean duration of follow-up, 2 years and 10 months). no differences in hiv loads and cd4 cells counts were observed between the hiv and hiv/hcv groups. alanine aminotransferase levels were higher (52 u/l versus 35 u/l; p<.05) and albumin levels were low ...200111418885
mother-to-child transmission of the human immunodeficiency virus in texas.the pediatric spectrum of hiv diseases (psd) project has been collecting data on hiv-exposed children in texas since 1989. these data have now been analyzed to describe mother-to-child transmission in texas and to provide much needed information on the magnitude of the pediatric hiv epidemic in the state.200111419503
relationships and diseases among drug users and nonusers.human immunodeficiency virus (hiv) and syphilis are relationship-based diseases that are typically transmitted by the cooperative activities (sex or drug injection) of two persons. a sample of 215 drug users and 52 sociodemographically matched nonusers was collected to examine the behaviors and relationships related to hiv and syphilis transmission. results showed that, although drug users had more risk opportunities (more sex partners and, of course, more injection partners) than nonusers, actu ...200111421249
the price of progress. getting insurers to cover new procedures is often difficult. 200111430199
the contribution of ethnicity to mycobacterium tuberculosis strain clustering.descriptive study of molecular epidemiologic patterns of tuberculosis cases among ethnic minorities in houston, texas.200111469256
hiv incidence among young men who have sex with men--seven u.s. cities, 1994-2000.twenty years after the first report on human immunodeficiency virus (hiv) infection in the united states, studies of sexually transmitted diseases (stds) and sexual behaviors suggest a resurgent hiv epidemic among men who have sex with men (msm). however, few recent studies have measured hiv incidence in this population. to determine hiv incidence among young msm, cdc analyzed data from the young men's survey (yms), a study that found a high prevalence of hiv and associated risks among msm aged ...200111475380
initial results of environmental monitoring in the texas rio grande valley.previous studies have suggested that a segment of human disease may be attributable to environmental exposures. these may include exposure to chemicals released from a broad range of natural and man-made sources. the purpose of this study was to develop the sampling methodology and prepare a preliminary database on the presence of various organic chemicals in environmental media in two south texas counties bordered by the rio grande river. a third county, located approximately 150 miles north of ...200111485214
human cytomegalovirus a sequence and ul144 variability in strains from infected children.human cytomegalovirus (hcmv) displays genetic polymorphisms. this variability may contribute to strain-specific tissue tropism and disease expression in hcmv-infected humans. to determine strain variability in a sequence and ul144 gene regions, 51 low-passage isolates from 44 hcmv-infected children were studied. isolates were obtained from 28 healthy children attending child care centers in iowa and from 16 congenitally infected infants born in texas. isolates demonstrated substantial nucleotide ...200111505449
seroprevalence of kaposi's sarcoma-associated herpesvirus infection among blood donors from texas.kaposi's sarcoma-associated herpesvirus (kshv), a gammaherpesvirus recently discovered among aids patients with kaposi's sarcoma, is a potential candidate for screening in blood and plasma donors. while a number of studies have assessed kshv infection among u.s. blood donors, larger-scale population-based studies would be necessary to develop more refined estimates of the magnitude and variation of kshv infection across different geographic regions of the u.s. blood supply. the goal of the prese ...200111557184
usefulness of cardiorespiratory fitness as a predictor of all-cause and cardiovascular disease mortality in men with systemic hypertension.there is an inverse gradient of mortality across levels of cardiorespiratory fitness in healthy adults; however, the association of fitness to mortality in persons with comorbidities such as hypertension is not fully understood. this study quantifies the relation of cardiorespiratory fitness to all-cause mortality and cardiovascular disease (cvd) mortality in hypertensive men. in this observational cohort study, we calculated death rates for low, moderate, and high fitness categories in normoten ...200111564389
sample exchange to compare insulin measurements between the san antonio heart study and the framingham offspring study.lack of assay standardization has precluded cross-study comparison of insulin levels. we exchanged blood samples between the san antonio heart and framingham offspring studies to compare insulin measurements. two randomly selected specimens were chosen for each non-diabetic man and woman in each of the bottom four quintiles and top two deciles of the originally assayed fasting and 2-hour post-challenge insulin distributions: 48 plasma samples from framingham, and after further stratification by ...200111576815
tuberculosis in the foreign-born population of tarrant county, texas by immigration status.the epidemiology of tuberculosis is changing in the united states as a result of immigration, yet the extent to which different classes of immigrants contribute to overall morbidity is unknown. tuberculosis in nonimmigrant visitors is of particular interest as they are currently exempt from screening requirements. we conducted a prospective survey of all culture-positive tuberculosis patients in tarrant county, texas from 1/98 to 12/00. immigration status of foreign-born patients was classified ...200111587977
empowerment, span of control, and safety performance in work teams after workforce reduction.relationships of empowerment and span of control with 2 safety measures (unsafe behaviors and accidents) were investigated among 24 workgroups comprising 531 employees of a large chemical company in 3 u.s. states. the company recently implemented a reengineering process. data were from an anonymous survey (unsafe behaviors), company records (accidents, span of control), and trained expert raters (empowerment). span of control (positively) and level of empowerment (negatively) correlated with bot ...200111605822
genotype by smoking interaction for leptin levels in the san antonio family heart study.recent studies reported a marked inverse effect of smoking on serum levels of leptin (an adipocyte derived protein), offering a possible explanation for variation in body weight between smokers and non-smokers. the goal of this study was to examine the genetic architecture of the response to smoking in leptin levels using data from the san antonio family heart study. we employed a variance decomposition analysis using maximum likelihood methods to model genotype by smoking interactions for lepti ...200211788957
man convicted of viatical fraud wins reduction in restitution. 200211905173
common deletion of smad4 in juvenile polyposis is a mutational hotspot.juvenile polyposis (jp) is an autosomal dominant syndrome in which affected patients develop upper- and/or lower-gastrointestinal (gi) polyps. a subset of families with jp have germline mutations in the smad4 (madh4) gene and are at increased risk of gi cancers. to date, six families with jp have been described as having the same smad4 deletion (1244-1247delagac). the objective of the present study is to determine whether this deletion is a common ancestral mutation or a mutational hotspot. dna ...200211920286
linkage of high-density lipoprotein-cholesterol concentrations to a locus on chromosome 9p in mexican americans.high-density lipoproteins (hdls) are anti-atherogenic lipoproteins that have a major role in transporting cholesterol from peripheral tissues to the liver, where it is removed. epidemiologic studies have shown that low levels of high-density lipoprotein-cholesterol (hdl-c) are associated with an increased incidence of coronary heart disease and an increased mortality rate, indicating a protective role of high concentrations of hdl-c against atherogenesis and the development of coronary heart dis ...200211743583
ethnic divergence and linkage disequilibrium of novel snps in the human nli-if gene: evidence of human origin and lack of association with tuberculosis susceptibility.sequence variation in the human genome has been used as a tool in studying human diseases and the evolutionary history of man. a human inherited predisposition to tuberculosis has been suggested and studied; however. genetic mechanisms are still ambiguous. in the present study, we scanned the regulatory and coding region of nuclear lim interactor-interacting factor gene (nli-if), which is physically close to the tuberculosis-associated gene nramp1. thirteen biallelic single-nucleotide polymorphi ...200211950066
the sam and ann barshop center for longevity and aging studies: the university of texas health science center at san antonio.the sam and ann barshop center for longevity and aging studies is a focal point for advanced research designed exclusively to study the genes involved in aging and the diseases of aging. the research performed at the barshop center is based on a solid foundation of nearly twenty-five years of aging research at the university of texas health science center at san antonio. internationally recognized scientists in aging are now leading innovative research programs using state-of-the-art technologie ...200212213546
mycobacterium simiae pseudo-outbreak resulting from a contaminated hospital water supply in houston, texas.various species of nontuberculous mycobacteria are known to cause nosocomial pseudo-outbreaks, but there have been no detailed reports of nosocomial mycobacterium simiae pseudo-outbreaks. from april 1997 through february 2001, we recovered 65 m. simiae isolates from 62 patients at a community teaching hospital in houston, texas. the organism was grown in various water samples obtained in the hospital building and in professional building 1 but not in professional building 2, which has a separate ...200212228816
5' dinucleotide repeat polymorphism of nramp1 and susceptibility to tuberculosis among caucasian patients in houston, texas.houston tuberculosis initiative (hti) and baylor college of medicine, houston, texas.200212234138
ergonomics & retention.the visiting nurse association of texas found that the impact of repetitive motion injuries on their office staff was costing them almost $200,000 a year. they formed a committee to design a cumulative trauma disorder prevention program. since that time repetitive motion injuries have decreased dramatically and the program has assisted in staff retention.200212244808
tropical storm allison rapid needs assessment--houston, texas, june 2001.on june 5, 2001, tropical storm allison made landfall on galveston island, texas. during the next 2 days, the system soaked much of southeast texas and south-central louisiana with more than 10 inches of rain as it moved slowly northward. on june 7, the storm made a clockwise loop back to the southwest, bringing even more rain to already drenched areas. the record rainfall caused billions of dollars in flood-related damage and approximately 25 deaths and led to a presidential disaster, declarati ...200212018382
geographic association of rickettsia felis-infected opossums with human murine typhus, texas.application of molecular diagnostic technology in the past 10 years has resulted in the discovery of several new species of pathogenic rickettsiae, including rickettsia felis. as more sequence information for rickettsial genes has become available, the data have been used to reclassify rickettsial species and to develop new diagnostic tools for analysis of mixed rickettsial pathogens. r. felis has been associated with opossums and their fleas in texas and california. because r. felis can cause h ...200212023908
long-term variation in mercury concentrations in estuarine organisms with changes in releases into lavaca bay, texas.mercury releases into lavaca bay resulted in public health notices and a fishing closure for crabs and finfish. mercury containing wastewater discharges were halted in 1970, but sediments were contaminated with mercury. the sediments are a source of mercury to the benthic food web via methylation. mercury in water column feeding organisms has decreased markedly. concentrations in benthic food web organisms remain elevated. human consumption concerns for oysters have ended, but a closure for fish ...200212269483
prenatal hiv testing in private ob-gyn practices in texas.this study evaluates the prenatal human immunodeficiency virus (hiv) testing behaviors of private obstetrics and gynecology practitioners in texas. a statewide telephone survey of 614 providers of prenatal care determined the level of hiv testing, how testing is offered, and patient acceptance of the test. ninety-nine percent of the practices offered hiv testing to all their pregnant patients, and 96% of the practices included hiv testing in the routine panel of tests for pregnant patients. more ...200212043395
a possible trend suggesting increased abuse from coricidin exposures reported to the texas poison network: comparing 1998 to 1999.coricidin products seemed to be one of the over-the-counter medications being reportedly abused by adolescents, as observed from the texas poison center network data. this retrospective chart review investigated the occurrence of abuse, developed a patient profile, and defined the clinical effects resulting from the abuse of coricidin products. data collected from the texas poison center network toxic exposure surveillance system database included human exposures between 1998 and 1999, patients ...200212046973
"managing the unmanageable" the u.s. department of health and human services, 1989-1993.the author served as the 17th u.s. secretary of health and human services, from march 1, 1989 until january 20, 1993. the department had 250 programs and 38 percent of the expenditures of the federal government ($600.0 billion), the fourth largest budget in the world. the history of the department included the fact that the tenure of previous secretaries had ranged from only eight months up to 37 months, and had averaged 27.5 months, resulting in the view that the department was unmanageable. th ...200212053720
prevalence of visual symptoms among patients with newly diagnosed cytomegalovirus retinitis.to determine the prevalence and type of visual symptoms among human immunodeficiency virus (hiv)-positive patients with newly diagnosed cytomegalovirus (cmv) retinitis.200212055459
presence of the human leukocyte antigen class ii gene drb1*1101 predicts interferon gamma levels and disease recurrence in melanoma patients.increased interferon gamma (ifn-gamma) levels are an independent predictor of melanoma recurrence. human leukocyte antigen (hla) class ii genes can regulate cytokine production; we investigated whether these genes would predict ifn-gamma levels and recurrence in melanoma patients.200212095976
high prevalence of human herpesvirus 8 (hhv-8) infection in south texas children.human herpesvirus 8 (hhv-8), also known as kaposi's sarcoma-associated herpesvirus, is etiologically associated with kaposi's sarcoma and other rare malignancies. hhv-8 infection is common in certain areas of africa and italy, but occurs in only 0-15% of populations in north america and europe. the epidemiology and prevalence of hhv-8 infection among children in the united states has not been determined, but is assumed to be low based on limited studies. the objective of this study was to determ ...200212116002
the impact of influenza in children.the highest infection rates with influenza virus occur in young children because of their lack of prior immunity and prior exposure to the virus. most children with influenza virus infection are healthy otherwise. previously healthy children who have influenza in their first year of life have a substantial risk for developing serious disease. an underlying chronic medical condition further increases this risk. infants, young children, and children with underlying conditions have the highest rate ...200212122955
downregulation of metabolic gene expression in failing human heart before and after mechanical unloading.we have previously shown that several metabolic genes are downregulated in the failing human heart. we now tested the hypothesis that mechanical unloading might reverse this process.200212145475
transmission of drug-resistant tuberculosis in texas and mexico.to examine the transmission of drug-resistant (dr) tuberculosis between texas and mexico, mycobacterium tuberculosis isolates resistant to one or more of the first-line antimycobacterial drugs were obtained from 606 patients who resided in texas and 313 patients who resided in mexico, primarily within the state of tamaulipas. the isolates were genotyped by is6110-based restriction fragment length polymorphism (rflp) analysis and spoligotyping. of the 919 isolates genotyped, 413 (45%) grouped int ...200212149319
epstein-barr virus in gastric adenocarcinomas: association with ethnicity and cdkn2a promoter methylation.it has been shown previously (by immunohistochemistry) that gastric adenocarcinomas harbouring epstein-barr virus (ebv) frequently lose p16 protein. this study aimed to examine the mechanisms of inactivation of the cdkn2a gene and correlate the results with clinicopathological features.200212194996
syringe type and drug injector risk for hiv infection: a case study in texas.studies of accidental needlestick exposure to blood containing human immunodeficiency virus (hiv) have shown that the volume of blood in an exposure is a strong predictor of subsequent infection. illicit drug injectors, a group at elevated risk for hiv transmission, use syringes manufactured in two styles, one of which (the integral cannula type) retains substantially less blood after intravenous use than the other (the detachable needle type). in this report, we examine some of the factors asso ...200212365524
laparoscopic versus open retroperitoneal lymph node dissection: a cost analysis.laparoscopic retroperitoneal lymph node dissection is significantly less morbid than open retroperitoneal lymph node dissection but it is generally more costly due to longer operative time and disposable equipment. in response to budgetary pressure at our large county hospital we identified the cost components of laparoscopic retroperitoneal lymph node dissection that could be targeted to decrease procedure costs before expanding our laparoscopic retroperitoneal lymph node dissection program.200212394682
lack of p21(cip1) dna methylation in acute lymphocytic leukemia. 200212412576
theobald smith--the discoverer of ticks as vectors of disease.the cause of texas fever in cattle, which is characterised by lysis of erythrocytes leading to anaemia, icterus, haemoglobinuria, and death, remained unsolved for many decades and assorted theories were proposed as an explanation for a disease being transmitted by apparently healthy animals. from 1889 to 1893, theobald smith and frederick l. kilbourne could demonstrate in elegantly conducted experiments how the disease was spread from cattle to cattle by ticks serving as the vector of transmissi ...200212422586
mismatch of school desks and chairs by ethnicity and grade level in middle school.the purpose of this study was to compare anthropometric measurements of children/adolescent (6th grade - 8th grade) and use these measurements to determine fit by ethnicity and grade level across three common classroom desks and chairs.200212441567
comparison of active and passive surveillance for cerebrovascular disease: the brain attack surveillance in corpus christi (basic) project.to provide a scientific rationale for choosing an optimal stroke surveillance method, the authors compared active surveillance with passive surveillance. the methods involved ascertaining cerebrovascular events that occurred in nueces county, texas, during calendar year 2000. active methods utilized screening of hospital and emergency department logs and routine visiting of hospital wards and out-of-hospital sources. passive means relied on international classification of diseases, ninth revisio ...200212446264
rabies surveillance in the united states during 2001.during 2001, 49 states and puerto rico reported 7,437 cases of rabies in nonhuman animals and 1 case in a human being to the centers for disease control and prevention, an increase of < 1% from 7,364 cases in nonhuman animals and 5 human cases reported in 2000. more than 93% (6,939 cases) were in wild animals, whereas 6.7% (497 cases) were in domestic species (compared with 93.0% in wild animals and 6.9% in domestic species in 2000). the number of cases reported in 2001 increased among bats, cat ...200212494966
determination of the occurrence of arcobacter butzleri in beef and dairy cattle from texas by various isolation methods.arcobacter butzleri is a pathogenic bacterium that has been found in dairy cattle, pigs, poultry, and humans. as of this writing, there are no data on the incidence of a. butzleri in beef cattle. given the differences in rearing practices used for feedlot cattle and those used for dairy cattle, differences in the incidences of this organism in various types of cattle may also exist. numerous culture methods have been used to isolate a. butzleri, but there are few data on the comparative efficaci ...200212495000
building the legal foundation for an effective public health system.work has been underway nationally since the mid-1990s to equip state and community public health systems with the infrastructure needed to perform essential public health services. key components of that infrastructure are a competent workforce, information and communication systems, health department and laboratory capacity, and legal authorities. as part of this transformative work, standards and assessment tools have been developed to measure the capacity and actual performance of public heal ...200212508502
adult blood lead epidemiology and surveillance--united states, 1998-2001.elevated blood lead levels (blls) in adults can damage the cardiovascular, central nervous, reproductive, hematologic, and renal systems. the majority of cases are workplace-related. u.s. department of health and human services recommends that blls among all adults be reduced to < 25 microg/dl. the highest bll acceptable by standards of the u.s. occupational safety and health administration is 40 microg/dl. the mean bll of adults in the united states is < 3 microg/dl.200212528812
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