Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| viral and bacterial antibody responses in multiple sclerosis. | an imprint electroimmunofixation method (ieif) was used to characterize antibodies to eight viral antigens (measles, mumps, rubella, herpes simplex type 1, varicella-zoster, vaccinia, cytomegalovirus, adenovirus) and four bacterial antigens (beta-hemolytic streptococcus, hemophilus influenzae type b, escherichia coli, enterococcus) in serum and cerebrospinal fluid (csf) of 12 patients with multiple sclerosis (ms). twelve patients matched for age and sex sex served as controls. evidence for intra ... | 1980 | 6254433 |
| cleavage and methylation of dna by the restriction endonuclease hinfiii isolated from haemophilus influenzae rf. | 1980 | 6265646 | |
| an eleven-base-pair sequence determines the specificity of dna uptake in haemophilus transformation. | only certain dna fragments are taken up efficiently by component haemophilus cells; this implies that efficient uptake requires the presence of a specific nucleotide sequence on the incoming dna (sisco and smith, 1979). to determine the structure of this "uptake site", we have isolated and sequenced four small fragments of cloned h. parainfluenzae dna which retain the ability to be taken up by cells. these fragments have a sequence of eleven base pairs in common, 5'-aagtgcggtca-3' and ethylation ... | 1980 | 6260577 |
| restriction endonucleases from three strains of haemophilus influenzae. | the restriction endonucleases, hin p1 i1), hin s1 i and hin s2 i are isolated from three strains of haemophilus influenzae respectively. by polymin p treatment, ammonium sulphate, precipitation and column chromatography on phosphocellulose and on heparin-sepharose hin p1 i is partially purified. no contaminating deoxyribonuclease activities have been detected in this purified enzyme preparation. the fact that the digestion patterns of hin p2 i and hha i on phage lambda, plasmids cole1 an pbr 322 ... | 1980 | 6262907 |
| treatment of experimental haemophilus influenzae type b meningitis with 1-oxa-beta-lactam (ly127935). | 1-oxa-beta-lactam (ly127935) (shionogi 6059-s) is a new type beta-lactam antibiotic having a broad spectrum of antibacterial activity. it is highly active against ampicillin-resistant strains of haemophilus influenzae exhibiting minimal inhibitory concentrations as low as 0.06 microgram/ml. this compound also has the ability to penetrate into the cerebrospinal fluid of both normal and infected infant rats and attains approximately 10% of the corresponding blood levels. ly127935 was evaluated for ... | 1980 | 6446260 |
| a study of the in vitro activity of cefoperazone: a comparison with other beta-lactam antibiotics. | 1980 | 6446391 | |
| clinical trials with cefoperazone in the field of internal medicine in japan. | a total of 466 patients were treated with cefoperazone. the drug was usually administered by drip infusion of 2 to 4 gm/day. therapy was described as markedly effective and moderately effective in 64 of 77 patients (83.1%) treated for urinary tract infections; 253 of 316 patients (80.1%) treated for respiratory infections; 37 of 48 patients (77.1%) treated for liver biliary duct infections; ten of 16 patients (62.5%) treated for septicemia; and seven of nine patients (77.8%) being treated for ot ... | 1980 | 6446392 |
| microbiological studies on cefoperazone. | 1980 | 6446395 | |
| in vitro studies of moxalactam (ly127935), a new beta-lactam antibiotic with significant activity against gram-negative bacteria. | moxalactam (ly127935) is a new beta-lactam antibiotic which is chemically related to the cephalosporins. the agent is highly active against the enterobacteriaceae, with most organisms sensitive to 0.1 mcg/ml or less. it is also active at low concentration against gentamicin-resistant strains of providencia and serratia. minimal inhibitory concentrations of moxalactam for pseudomonas aeruginosa are approximately four-fold lower than those of carbenicillin for the same isolates. it is highly activ ... | 1980 | 6447671 |
| the in vitro antibacterial activity of ly127935 (6059s), a novel 1-oxa-beta-lactam antibiotic. | 1980 | 6447682 | |
| moxalactam (6059-s), a novel 1-oxa-beta-lactam with an expanded antibacterial spectrum: laboratory evaluation. | moxalactam (6059-s) {7beta-[2-carboxy-2-(4-hydroxyphenyl)acetamido]-7alpha-methoxy-3-[[(1-methyl-1h-tetrazol-5-yl)thio]-methyl]-1-oxa-1-dethia-3-cephem-4- carboxylic acid disodium salt} is a new semisynthetic 1-oxa-beta-lactam derivative for parenteral use. it was highly active against a broad range of gram-negative microorganisms, including those resistant to other cephalosporins. moreover, it had widely expanded antibacterial spectra which included haemophilus influenzae, indole-positive prote ... | 1980 | 6448572 |
| effect of inoculum size and beta-lactamase production on in vitro activity of new cephalosporins against haemophilus species. | sixty-three strains of haemophilus species, 38 of which were beta-lactamase producers (37 h. influenzae type b, 1 h. parainfluenzae) and 25 of which were beta-lactamase negative (20 h. influenzae, 5 h. parainfluenzae), were tested for susceptibility to cefoxitin, moxalactam (ly127935) (lilly), cefsulodin (cgp 7174 e, ciba), and cefoperazone (t 1551, pfizer). cefsulodin was relatively inactive at both low and high inocula. ly127935 and cefoperazone displayed inoculum-dependent bactericidal activi ... | 1980 | 6448575 |
| in vitro susceptibility of 104 clinical isolates of haemophilus influenzae to moxalactam (ly127935), ampicillin, chloramphenicol, and ticarcillin. | a total of 104 strains of haemophilus influenzae isolated from pediatric patients over a 1-year period were tested for susceptibility to moxalactam (ly127935), ampicillin, chloramphenicol, and ticarcillin. of these strains, 30 produced beta-lactamase. ly127935 inhibited 99% of the strains at a concentration of 0.125 microgram/ml; the remaining strain was inhibited by this antibiotic at 0.25 microgram/ml. beta-lactamase-producing strains were inhibited by ampicillin at greater than or equal to 2 ... | 1980 | 6448579 |
| comparative in vitro appraisal of piperacillin, including its activity against salmonella typhi. | piperacillin was evaluated in vitro against 711 clinical isolates of aerobic and anerobic gram-positive and gram-negative bacteria, including 76 isolates of salmonella typhi. piperacillin minimum inhibitory concentrations (mics) and minimum bactericidal concentrations (mbcs) were compared with those of a range of beta-lactam, aminoglycoside, and other antimicrobial agents, and inoculum size effects were considered. the relationship between dilution and disk diffusion tests was studied by regress ... | 1980 | 6449903 |
| [fundamental and clinical studies of cefoperazone in children (author's transl)]. | as a result of conducting experimental and clinical tests with the newly developed cephalosporin, cefoperazone (cpz), the following conclusions were obtained: (1) when tested against 10 strains of staphylococcus aureus and 16 strains of staphylococcus epidermidis, the antibacterial activity of cpz was found to be weaker than that of cez. against 5 strains of a-beta-streptococcus and 4 strains of streptococcus pneumoniae, both cpz and cez exhibited similar excellent antibacterial activity. cpz wa ... | 1980 | 6451730 |
| [results of application of cefoperazone to pediatric infections (author's transl)]. | cefoperazone (cpz) was studied clinically and the following results were obtained. the drug was administered to 21 cases of bacterial infections; respiratory tract infection (17), lymphadenitis (1), urinary tract infection (1), enterocolitis (1) and purulent meningitis (1). the daily dose was 50 approximately 125 mg/kg. the drug was given by one-shot intravenous injection, 3 approximately 4 times a day and the duration of administration was from 3 approximately 18 days. the overall efficacy rate ... | 1980 | 6452541 |
| [concentrations of mezlocillin in cerebrospinal fluid in vira meningitis (author's transl)]. | the concentrations of mezlocillin in the cerebrospinal fluid were measured in ten patients with viral meningitis after a single infusion of 5 g lasting 30 minutes. one to two hours after infusion the csf concentrations were between 0.1 mcg/ml and 1.6 mcg/ml, and thus exceeded the minimal inhibitory concentrations of neisseria meningitidis and diplococcus pneumoniae, the most common pathogens in bacterial meningitis in adults. the minimal inhibitory concentration of ampicillin-sensitive strains o ... | 1980 | 6457803 |
| rapid differentiation of the major causative agents of bacterial meningitis by use of frequency-pulsed electron capture gas-liquid chromatograph: analysis of acids. | the major causative agents of bacterial meningitis, haemophilus influenzae serogroup b, neisseria meningitidis serogroups b and c, klebsiella pneumoniae, streptococcus pneumoniae, and two types of escherichia coli, were cultured in a modified chemically defined catlin medium and in a commercial version of the unmodified catlin medium. the spent media were extracted under acidic conditions, and electron-capturing derivatives were prepared by derivatization with trichloroethanol or haptafluorobuty ... | 1980 | 6766463 |
| rapid differentiation of the major causative agents of bacterial meningitis by use of frequency-pulsed electron capture gas-liquid chromatography: analysis of amines. | the major causative agents of bacterial meningitis (haemophilus influenzae serogroup b, neisseria meningitidis serogroups b and c, klebsiella pneumoniae, steptococcus pneumoniae, and two types of escherichia coli) were cultured in a chemically defined medium, and selected strains were further studied in todd-hewitt medium. after acidic extraction of the spent media with chloroform, a basic extraction was made with chloroform to obtain amines. a third extraction was performed on re-acidified todd ... | 1980 | 6766464 |
| haemophilus influenzae bacteremia and meningitis in infant primates. | 1980 | 6766493 | |
| from the national institute of allergy and infectious diseases. summary of an international symposium on potentiation of the immune response to vaccines. | 1980 | 6767789 | |
| effect of viral infections on pulmonary function in patients with chronic obstructive pulmonary diseases. | the effect of 100 separate viral infections of the respiratory tract on pulmonary function was evaluated prospectively over an eight-year period in 84 patients with chronic obstructive pulmonary diseases and in eight normal subjects. some viral infections were associated with small acute declines in forced vital capacity and/or 1-sec forced expiratory volume of 25-300 ml. these declines were detectable only during the 90-day period after infection. the greatest abnormalities of pulmonary functio ... | 1980 | 6767794 |
| [studies on an extract from haemophilus influenzae type a. i.--antigenic and immunogenic studies (author's transl)]. | haemophilus influenzae is the bacteria most commonly found in chronical bronchitis not treated by antibiotic therapy. experimental studies have suggested that the destruction of the ciliated respiratory epithelium is in conjunction with the toxic product of the cell-wall of this bacteria. endotoxin is extracted by phenol-water procedure. toxicity is reduced by mild hydrolysis. antigenicity of the preparation is controlled by gel diffusion in a parallel sides-tank diffusion and electroimmunodiffu ... | 1980 | 6768051 |
| cellulitis: a prospective study. | we prospectively studied 20 children, ages 2 to 12 years, seen with cellulitis. each child had a complete blood count, a blood culture, and a culture of an aspirate from the lesion. the age of the child, the fever, and the extent of cellulitis determined whether the child was hospitalized. outpatient antibiotic therapy was penicillin or dicloxacillin. four children (20%) had an infection on the upper extremity: 14 (70%), the leg; 1 (5%), the forehead; and one (5%), the periorbital area. three ch ... | 1980 | 6768328 |
| iga1 proteases from haemophilus influenzae, streptococcus pneumoniae, neisseria meningitidis, and streptococcus sanguis: comparative immunochemical studies. | iga1 proteases from h. influenzae, n. meningitidis, s. pneumoniae, and s. sanguis were compared with respect to site of cleavage in the iga1 molecule and edta sensitivity. proteases from s. sanguis and s. pneumoniae cleaved the pro (227)-thr (228) bond within the hinge region of the alpha 1 chain and were inhibited by edta. h. influenzae iga1 protease cleaved the pro (231)-ser (232) peptide bond. the activity of iga1 proteases from h. influenzae and n. meningitidis was unaffected by edta. purifi ... | 1980 | 6768797 |
| [purulent meningitis in older children and adults (author's transl)]. | purulent meningitis is a clinical syndrome whose appearance is particularly influenced by heteropathogenesis and polyetiology in addition to a multitude of individual factors. symptomatology and type only become comprehensible, diagnosis, therapy and prognosis only become reconciled when the individual pathogenetic connections have been grasped and taken into consideration. the fate of the by no means rare meningitic diseases is so closely related to the professional experience of the doctors tr ... | 1980 | 6768996 |
| nucleic acid transport driven by ion gradient across cell membrane. | 1980 | 6769706 | |
| use of preserved organisms for individual test-use quality control of bacterial typing antisera. | bacterial antigens representing 14 of the most common clinical isolates requiring serological confirmation for identification were prepared. these antigens were stable for periods in excess of 5 months, readily available, and sero-specific. use of these antigens for quality control of bacterial typing antisera increased the accuracy, reduced the technician time, and obviated the delay which otherwise occurred while stock isolates were subcultured to provide a sero-specific control for this proce ... | 1980 | 6769951 |
| cefaclor in treatment of otitis media and pharyngitis in children. | the safety and efficacy of cefaclor were compared with amoxicillin trihydrate in the treatment of 130 cases of otitis media, and with penicillin v potassium in 88 cases of streptococcal pharyngitis in two single-blind controlled studies. patients with otitis media received approximately 40 mg/kg/day of cefaclor or amoxicillin trihydrate for ten days to three weeks; patients with pharyngitis received 20 mg/kg/day of cefaclor or penicillin v potassium for ten days. overall, patients who received c ... | 1980 | 6770673 |
| comparison of in vitro activity of gr 20263, a novel cephalosporin derivative, with activities of other beta-lactam compounds. | the in vitro activity of gr 20263, a new cephalosporin, was compared primarily with the activities of moxalactam (ly 127935), cefotaxime, cefoxitin, cefuroxime, and cefazolin against 293 clinical isolates of a variety of gram-positive and -negative bacteria. the minimal inhibitory concentrations of gr 20263 for 90% of group isolates were between 0.06 and 0.5 microgram/ml for the enterobacteriaceae, haemophilus influenzae, neisseria gonorrhoeae, and lancefield group a beta-hemolytic streptococci; ... | 1980 | 6772097 |
| incidence and risk of cross-colonization in cystic fibrosis holiday camps. | 1980 | 6772098 | |
| microorganisms isolated from blood and cerebrospinal fluid in a general hospital. clinical implications. | this study is a review of 1,040 significant positive blood cultures from 415 patients, and 44 positive cerebrospinal fluid cultures from 44 patients treated at the meir general hospital during the period 1976-78. the most frequent isolates from blood cultures were escherichia coli, staphylococcus aureus and klebsiella pneumoniae. the most frequent isolates from cerebrospinal fluid cultures were streptococcus pneumoniae, haemophilus influenzae and neisseria meningitidis, which were present in sim ... | 1980 | 6772597 |
| acute nongonococcal infectious arthritis. evaluation of risk factors, therapy, and outcome. | a retrospective analysis of 71 nongonococcal joint infections in 63 patients is reported. staphylococcus aureus was isolated from 59% of the patients. five patients died as a result of infections. the outcome in gram-negative joint infections was similar to the overall outcome in the entire series of patients. all 11 joints with infected prostheses ultimately required removal of the prostheses. all patients were treated with appropriate parenteral antibiotics, and surgical intervention was used ... | 1980 | 6773530 |
| [can chloramphenicol be combined with beta-lactam antibiotics? (author's transl)]. | the effect was studied of combinations of chloramphenicol with beta-lactam antibiotics, such as penicillin, ampicillin, cefotiam and cefotaxime, on 20 strains each of haemophilus influenzae, streptococcus pneumoniae and neisseria meningitidis. no antagonism was observed using the checkerboard titration method. in most cases no interaction could be established. an evaluation by the fractional inhibitory concentration index was discussed: only values above 2 were interpreted as antagonism. the min ... | 1980 | 6773885 |
| recovery of pathogenic bacteria from cerebrospinal fluid. | we studied the conditions necessary for optimal recovery of bacteria from cerebrospinal fluid. our results indicated that streptopcoccus pneumoniae, neisseria meningitidis, and haemophilus influenzae can be quantitatively recovered in the sediment after centrifugation at 1,500 x g for 15 min. equivalent numbers of bacteria were recovered by centrifugation or filtration of antibiotic-free cerebrospinal fluid; however, bacterial recovery by filtration was less effective with antibiotic-supplemente ... | 1980 | 6775013 |
| ontogeny of the immune response as a basis of childhood disease. | 1980 | 6775062 | |
| cellulitis: bacterial etiology, clinical features, and laboratory findings. | 1980 | 6775063 | |
| [value of quantitative bacteriological examination of sputum in the evaluation of the effectiveness of chemotherapy of bacterial respiratory tract infections. i. bacteriological studies]. | 1980 | 6775309 | |
| [airborne microflora found in some stations of the metro in the hungarian capital of budapest (author's transl)]. | both the microflora and some physical parameters of the air in three underground railway (metro) stations were analysed. the air samples taken in the first two stations contained considerably more microbes, namely three times as many, than the sample from station no. 3. in the samples from the first two stations both the pathogenic and anthropogenic germs occured more frequently than in the samples from the third station. the normal flora consisted of gram-positive cocci/streptococci, micrococci ... | 1980 | 6775455 |
| bacteriology of sputum in cystic fibrosis: evaluation of dithiothreitol as a mucolytic agent. | liquefaction and homogenization have been recommended to ensure accurate, representative sputum cultures. we evaluated dithiothreitol (dtt) as mucolytic agent for culturing sputum samples obtained from 79 cystic fibrosis (cf) patients. liquefaction with dtt was not superior to direct plating of specimens for routine qualitative cultures. unliquefied sputum cultures failed to direct 3 of 47 pseudomonas aeruginosa isolates; dtt-treated specimens missed 5 of 13 candida albicans isolates. neither tr ... | 1980 | 6776135 |
| rapid diagnosis of infections caused by beta-lactamase-producing bacteria by means of an enzyme radioisotopic assay. | we developed a sensitive enzyme radioisotopic assay for the measurement of beta-lactamase, an enzyme produced by a number of pathogenic bacteria. this eria was 100-fold more sensitive than the commonly used iodometric or spectrophotometric assays for the measurement of beta-lactamase and, unlike these other assays, the eria was not significantly influenced by serum proteins or unlabeled penicillin. clinical specimens consisting of blood, peritoneal, pleural, and cerebrospinal fluids from patient ... | 1980 | 6776252 |
| [bacterial flora in exacerbation of chronic bronchitis in the light of bacteriological examination of sputum by the qualitative and quantitative methods]. | 1980 | 6776499 | |
| persistent effusions of the middle ear. cultures for anaerobic bacteria. | recent reports of isolation of bacteria from effusions of the middle ear taken from asymptomatic children have suggested a possible role for persistent bacterial infection in the etiology of prolonged effusions. to investigate the significance of anaerobic bacteria in such effusions, we obtained 51 samples of middle ear effusion (mee) from 30 children. after careful cleansing of the tympanic membrane with 70% alcohol, we performed tympanocentesis prior to performing a myringotomy. fastidious bac ... | 1980 | 6778286 |
| antibody coated bacteria in otitis media with effusions. | the significance of bacterial isolates of coagulase negative staphylococcus epidermidis and corynebacterium species in middle ear fluids remains controversial. this study was undertaken to evaluate the possible role of these organisms in different effusions. cultures were obtained from the external cartilaginous ear, bony canal, tympanic membrane, middle ear fluids, tonsils and nasopharynx of 93 patients at the time of myringotomy for otitis media with effusion. isolates of coagulase negative st ... | 1980 | 6778287 |
| evaluation of countercurrent immunoelectrophoresis as a diagnostic tool in bacterial otitis media. | the diagnostic efficiency of countercurrent immunoelectrophoresis (cie) and correlation of clinical and bacteriological data were studied in 184 middle ear effusions (mee) from 125 patients diagnosed as acute primary, acute recurrent otitis media, and chronic mee. significant differences between stage of otitis media (om), patient age and type of mee were found. streptococcus pneumoniae was isolated in 22% of the overall mee, 26% in the acute primary and 26% in acute recurrent om. among the s. p ... | 1980 | 6778289 |
| study of antibody levels in children with purulent otitis media. | a series of episodes of acute otitis media were studied with reference to the bacterial findings in the nasopharynx and the specific antibody response in a group of children nine months to ten years of age, with previous frequent episodes of acute otitis media, serum igg, igm and iga antibody levels against five polysaccharide antigens, namely haemophilus influenzae type b and streptococcus pneumoniae types 3, 6, 19 and 23, were studied by means of an enzyme-linked immunosorbent assay. the selec ... | 1980 | 6778291 |
| penicillin and acute otitis: short and long-term results. | the effect of peroral penicillin v (55 mg/kg/day) on acute otitis media was investigated in 149 children between the ages of one and ten years in a double-blind, placebo-controlled investigation. the parameters of the disease employed were symptom scores for earache, the use of analgetics, otoscopy, as well as tympanometry. the children were followed up for three months. penicillin had a significant effect on pain on the second day of treatment. the acute course of the disease was satisfactory i ... | 1980 | 6778324 |
| concentration of penicillin v in serum and middle ear exudate during treatment of acute otitis media. | sixty-one patients, aged six months to ten years, with acute purulent otitis media were treated with penicillin v for ten days. the drug was given twice a day in a total daily dose of 50 mg/kg body weight. the concentration of penicillin was determined in serum and in middle ear exudate on one of the first six days of treatment, 60, 120 or 180 minutes after administration of the drug. bacterial cultures were taken from the nasopharynx before and during treatment and from the middle ear exudate a ... | 1980 | 6778325 |
| antibiotic-resistant bacteria in otitis media with effusion. | eighty-two bacterial isolates recovered from the middle ear effusions (192) of children with otitis media with effusion (ome) were tested for antibiotic sensitivity. nearly 50% of all bacteria isolated were found to be resistant to penicillin, and in particular, 61% of the haemophilus isolates were penicillin-resistant; 48% of the haemophilus isolates were ampicillin-resistant. in addition, we we compared the bacterial recovery rate from effusions of patients who were receiving antibiotics with ... | 1980 | 6778326 |
| trimethoprim-sulfamethoxazole in the treatment of otitis media secondary to ampicillin-resistant strains of haemophilus influenzae. | between august 1977 and january 1979, 16 children (7 males and 9 females) ranging in age from 5 to 38 months (mean age 18 months) were treated with trimethoprim-sulfamethoxazole (tmp-smx) (40 mg/kg smx per 24 hours) for otitis media caused by beta-lactamase strains of ampicillin-resistant haemophilus influenzae. fourteen patients had failed after antecedent ten-day courses of ampicillin (9 patients) or amoxicillin (5 patients) therapy. the remaining two patients received only five days of ampici ... | 1980 | 6778328 |
| efficacy of pneumococcal vaccination against recurrent otitis media. preliminary results of a field trial in finland. | for this study, 781 children, and 3 to 83 months, after presenting with acute otitis media, were immunized with either 14-valent pneumococcal or haemophilus influenzae type b capsular polysaccharide vaccine. the vaccines were tolerated well. antibody responses to the 14 pneumococcal polysaccharide types, measured by radioimmunoassay, were fair to good and increased with age, with the exception of types 1, 6 and 12 to which the responses were generally poor. during the follow-up of 1-17 months, a ... | 1980 | 6778346 |
| microbiology of otitis media. | the microbiology of otitis media (om) has been documented by cultures of middle ear fluid (mef) obtained by needle aspiration. the results of studies of bacteriology of om from sweden, finland and the united states are very similar: streptococcus pneumoniae and haemophilus influenzae are the most important pathogens: gram-negative enteric bacilli are isolated from mef of approximately equal to 20% of infants to six weeks of age but are rarely present in mef of older children; group a beta hemoly ... | 1980 | 6778362 |
| [comparative studies of bacterial flora in the bronchial and pharyngeal secretions and sputum in bronchopulmonary diseases]. | 1980 | 6784116 | |
| an erysipelas-like scalp cellulitis due to haemophilus influenzae type b. | 1980 | 6965310 | |
| acute glossitis and septicemia owing to haemophilus influenzae type b. | 1980 | 6965336 | |
| hemophilus influenzae type b pneumonia with pneumatocele formation. | 1980 | 6965366 | |
| comparison of cotrimoxazole, ampicillin, and chloramphenicol in treatment of experimental haemophilus influenzae type b meningitis. | to evaluate cotrimoxazole in the treatment of bacterial meningitis, we compared its action with that of ampicillin and chloramphenicol in experimental haemophilus influenzae type b meningitis. both trimethoprim and sulfamethoxazole penetrated well into the cerebrospinal fluid of infected rabbits, reaching 40 and 26%, respectively, of their simultaneous serum levels. levels measured 30 and 60 min after intravenous injection exceeded the minimum inhibitory concentration of this combination for h. ... | 1980 | 6965442 |
| isolation of an ampicillin-resistant, non-beta-lactamase-producing strain of haemophilus influenzae. | a 79-year-old female developed endocarditis and meningitis due to an ampicillin-resistant, non-beta-lactamase-producing strain of haemophilus influenzae. carbenicillin and gentamicin therapy resulted in bacteriological and clinical cure. the mechanism of resistance of ampicillin-resistant, non-beta-lactamase-producing strains of h. influenzae is unknown. | 1980 | 6965443 |
| endophthalmitis complicating haemophilus influenzae type b meningitis. | in two children, pyogenic endophthalmitis developed simultaneously with haemophilus influenzae type b meningitis. the eye of one of the patients recovered fully; the eye of the other became phthisical and was enucleated. culturable or pathologically identifiable organisms were not found in either eye; nevertheless, it is suggested that these cases represented metastatic h influenzae type b endophthalmitis from a primary site of infection in the meninges. | 1980 | 6965450 |
| non-typable hemophilus influenzae sepsis in a child. | 1980 | 6965473 | |
| evaluation of chemotherapeutic agents in experimental haemophilus influenzae bacteremia and meningitis in infant rats. | procedures for evaluating the efficacy of chemotherapeutic agents in an infant rat model of haemophilus influenzae meningitis were developed. the results of efficacy studies with ampicillin, chloramphenicol, cefamandole, cefoxitin, and sq 13,426 were compared to activity in vitro. while most of the drugs tested were very active against the two strains of h. influenzae used in vitro, this activity was not in all cases translated into efficacy in vivo. pharmacokinetic studies using ampicillin or c ... | 1980 | 6965474 |
| buccal cellulitis in infants. a review and case report. | 1980 | 6965529 | |
| subscapular abscess due to haemophilus influenzae type b. | localized abscess formation is a rare but previously described manifestation of haemophilus influenzae infection. a majority of the reported cases were caused by nontypeable strains of h influenzae. we report a case of an extensive subscapular abscess due to beta-lactamase-negative h influenzae type b. this, to our knowledge, is the first such case described in english literature. | 1980 | 6965530 |
| haemophilus influenzae type b in a day care center: relationship of nasopharyngeal carriage to development of anticapsular antibody. | we measured anticapsular antibody to haemophilus influenzae type b by radioimmunoassay in sera from 55 children attending a day care center in which two cases of h influenzae type b disease had occurred. the children ranged in age from 2 months to 36 months. serum antibody levels in children attending the day care center were significantly higher than in age-matched controls (p less than .001), but in two different surveys one month apart 38% and 43% of the contacts had levels less than 100 ng/m ... | 1980 | 6965531 |
| [sensitivity of strains resistant to tetracycline]. | 1980 | 6965533 | |
| [doxycycline sensitivity of haemophilus]. | 1980 | 6965534 | |
| [chloramphenicol treatment of haemophilus influenzae meningitis in infants]. | 1980 | 6965536 | |
| inhibition of effects of isoprenaline and adrenaline by haemophilus influenzae vaccination [proceedings]. | 1980 | 6965598 | |
| structural studies of the haemophilus influenzae type f capsular polysaccharide. | 1980 | 6965610 | |
| structural studies of the capsular antigen from haemophilus influenzae type f. | 1980 | 6965611 | |
| use of trimethoprim-sulfamethoxazole against haemophilus influenzae. | 1980 | 6965718 | |
| in osteomyelitis the initial treatment is crucial. | 1980 | 6965756 | |
| reye syndrome associated with hemophilus influenzae infection. | a case of reye syndrome in an infant associated with culture-proven hemophilus influenzae type d infection and probable meningitis is presented. this represents the second such reported case and the first to be described in detail. the criteria for the clinical and chemical diagnosis of reye syndrome are reviewed. pertinent and abnormal features of this patient's presentation are discussed. the finding of a non-visualizing liver on technetium-99m sulfur colloid isotope scan and possible mechanis ... | 1980 | 6965903 |
| haemophilus influenzae infections in fresno county, california: a prospective study of the effects of age, race, and contact with a case on incidence of disease. | a prospective, population-based study of the incidence of infections with haemophilus influenzae in fresno county, california, was conducted. the average annual incidence or meningitis was 5.18 cases per 100,000 population, and of other invasive infections, 3.48 cases per 100,000. incidence rates were highest in infants, but 13% of infections and five of seven deaths were in adults, primarily in elderly individuals with compromised defenses. black children four years of age and younger were more ... | 1980 | 6965975 |
| bacterial adherence to pharyngeal cells during viral infection. | adherence of bacteria to pharyngeal cells from patients with naturally acquired acute respiratory illness and from volunteers experimentally infected with influenza virus vaccine was studied. increased adherence of staphylococcus aureus was found in both groups. in addition, haemophilus influenzae and streptococcus pneumoniae type i adhered in increased numbers to cells from volunteers experimentally infected with influenza virus. alterations in mucosal cells leading to increased bacterial adher ... | 1980 | 6965977 |
| simultaneous recovery of ampicillin-sensitive and ampicillin-resistant h. influenzae from blood. | 1980 | 6965981 | |
| simultaneous uvulitis and epiglottitis. | 1980 | 6965992 | |
| haemophilus influenzae sepsis leading to pericarditis despite antimicrobial therapy. | acute purulent pericarditis is a well-recognized, though infrequently seen, manifestation of systemic haemophilus influenzae type b disease. we recently studied two pediatric patients who developed signs of this septic complication during appropriate antibiotic treatment for bacteremia. these case reports should alert physicians to the possibility that pericarditis may become clinically evident in patients with systemic h. influenzae infections many days after initiation of appropriate therapy. ... | 1980 | 6966005 |
| intrauterine infection by non-capsulated haemophilus influenzae in a case of maternal immunodeficiency. | a 29-year-old woman with an upper respiratory tract infection due to haemophilus influenzae, gave birth to a premature infant who died after 3 h. the mother's strain was non-capsulated, as were the strains cultured from the infant's blood, lungs, nose, and throat. antigen analyses revealed, however, that the strains were not identical. the infant probably acquired the infection via the transplacental route. the uncommon infection was in this case attributed to a transient dysgammaglobulinemia in ... | 1980 | 6966070 |
| trimethoprim-sulfamethoxazole compared with ampicillin in the treatment of acute otitis media. | we treated 132 children with acute otitis media in a randomized trial comparing trimethoprim-sulfamethoxazole and ampicillin. the antibacterial efficacy of the drugs was assessed primarly from the results of cultures of middle ear aspirates obtained during or after the course of therapy; persistent, recurrent, and new infections of the middle ear were documented in both groups of patients but did not differ significantly. both drug regimens were well accepted by the patients and were not associa ... | 1980 | 6966331 |
| haemophilus influenzae from the middle ear of an adult with acute otitis media. | 1980 | 6966337 | |
| hemophilus influenzae purulent pericarditis in children: diagnostic and therapeutic considerations. | purulent pericarditis is an unusual complication of infection in infancy and has been associated with an extremely high mortality rate. early diagnosis followed by combined antibiotic therapy and surgical drainage of the pericardium has markedly improved survival. between april, 1975, and february, 1979, nine patients with purulent pericarditis secondary to hemophilus influenzae type b were treated at the oklahoma children's memorial hospital. in every case signs and symptoms of congestive heart ... | 1980 | 6966352 |
| diagnosis and management of acute epiglottitis -- report of 90 consecutive cases. | ninety children with acute epiglottitis were admitted from 1971 - 1977. lateral extended neck radiograph was found to be a quick, safe and reliable way to establish the diagnosis. out of 79, 77 (97%) had blood cultures yielding hemophilus influenzae type b. immediate institution of airway and antibiotics were the mainstay of treatment. all patients in the series survived. for short-term airway management, as in acute epiglottitis, nasotracheal intubation under general anesthesia was found to be ... | 1980 | 6966360 |
| mechanism of homospecific dna uptake in haemophilus influenzae transformation. | dna uptake by competent h. influenzae cells requires the presence of a specific base sequence (uptake site) on the entering dna duplex. this sequence is probably recognized by a receptor on the cell surface. we have examined the kinetics and stoichiometry of dna uptake by competent cells and have shown that the results are consistent with a simple model involving: 1) reversible binding of the dna uptake site to a cell surface receptor, 2) an irreversible step resulting in a commitment toward dna ... | 1980 | 6966371 |
| a case of quinsy. | 1980 | 6966373 | |
| microbiology of acute otitis media with particular reference to the feasibility of pneumococcal immunization. | middle-ear fluid was aspirated in 103 episodes of acute otitis media occurring in 100 south australian children aged from four months to 14 years in 1977, and in 1978. bacteria were cultured from the middle-ear fluid in 66% of cases, and viruses were grown in three cases in conjunction with bacteria. the bacteria grown were pneumococci in 30 cases (29%), haemophilus influenzae in 26 cases (25%), beta-haemolytic streptococci in 12 cases (12%) and neisseria spp. in six cases (6%). pneumococci and ... | 1980 | 6966374 |
| haemophilus influenzae: secondary spread. | 1980 | 6966449 | |
| serum bactericidal effect on capsulated and non-capsulated haemophilus influenzae. | 1980 | 6966461 | |
| hemophilus influenzae cellulitis. | 1980 | 6966466 | |
| lacunar defects in immunity. | 1980 | 6966562 | |
| haemophilus influenzae b infection in rats: effect of splenectomy on bloodstream and meningeal invasion after intravenous and intranasal inoculations. | we investigated the effect of splenectomy on the susceptibility of rats to intravenous or intranasal inoculation of haemophilus influenzae, type b. the 50% lethal dose for asplenic rats inoculated either by intravenous (i.v.) (10(4.7)) or intranasal (i.n.) (10(4.6)) injection was similar, but significantly lower than the 50% lethal dose value in sham-operated rats (10(8.6) i.v. and 10(9.0) i.n.). mean survival time was significantly longer for asplenic rats inoculated i.n. (49.3 h) compared to a ... | 1980 | 6966613 |
| properties of haemophilus influenzae mutants that are slightly recombination deficient and carry a mutation in the rec-1 gene region. | the highly recombination-deficient rec-1 mutants of haemophilus influenzae are, as far as tested, equivalent to reca mutants of escherichia coli. by selection for mutations in the rec-1 gene of h. influenzae, mutants designated ird (intermediary recombination-deficient) mutants were isolated; these mutants were much less recombination deficient (degree of transformability, 0.2 to 30% of wild-type value) than previously isolated rec-1 mutants (degree of transformability, 0.0001% of wild-type valu ... | 1980 | 6966628 |
| chromosomally integrated conjugative plasmids are common in antibiotic-resistant haemophilus influenzae. | twenty-three highly antibiotic-resistant strains of haemophilus influenzae and two of haemophilus parainfluenzae without detectable large plasmids were examined for conjugative transfer of their resistance to h. influenzae strain rd or to other strains. very inefficient transfer was observed for 18 h. influenzae strains and 1 h. parainfluenzae strain. all h. influenzae transcipients carried a large plasmid, and they were in turn efficient donors of their resistances in standard conjugation cross ... | 1980 | 6966629 |
| effect of upper respiratory tract infection on eustachian tube ventilatory function in the preschool child. | a prospective tympanometric and microbiologic study of 28 pre-schoolchildren was undertaken to better define the effect of acute uri on induction of eustachian tube dysfunction. significant negative middle ear pressure was present in 12.7% of tympanograms from well children. however, abnormal tympanograms were detected during 74.7% of acute uris. the abnormality was present on day 1 or 2 of illness in the majority of cases; 10.1% of illnesses were complicated by ome. respiratory viruses or sp we ... | 1980 | 6966684 |
| the increasing frequency of beta-lactamase-producing haemophilus influenzae b. | 1980 | 6966695 | |
| correlation between serum igg-2 concentrations and the antibody response to bacterial polysaccharide antigens. | we measured serum concentrations of immunoglobulin classes and igg subclasses in 53 patients who had completed treatment for hodgkin's disease and in 10 healthy adults. we wished to determine the relation of these classes and subclasses to the subjects' antibody responses to bacterial polysaccharide and viral protein antigens. mean levels of the igg-2 subclass were significantly lower in patients treated with both radiation and chemotherapy than in controls (p less than 0.05). the level of igg-2 ... | 1980 | 6966763 |
| bacteremia in childhood. | review of the bacteriology records of a university hospital pediatric service for a 30-month period revealed 42 patients with hemophilus influenzae type b bacteremia and 30 patients with streptococcus pneumoniae bacteremia, all under age 10. eighty-eight percent of the hemophilus bacteremias and 7% of the pneumococcal bacteremias occurred in children less than 2 years of age. hemophilus bacteremia was seen mot frequently in the first year of life, in contrast to pneumococcal bacteremia which was ... | 1980 | 6966825 |
| [study of microflora of bronchial contents in chronic bronchitis]. | 1980 | 6966836 | |
| [various prospective approaches to the treatment of nonspecific lung diseases]. | 1980 | 6966837 | |
| haemophilus parainfluenzae pneumonia. | 1980 | 6966913 |