Publications

cephalexin in the management of bacteriuria.	this report evaluates the effectiveness of cephalexin in the treatment of bacteriuria in 93 children. cephalexin therapy eradicated sensitive organisms in 97 per cent of the cases regardless of recurrence, structural abnormality, or status of renal function. nevertheless, recurrences with a new, resistant organism occurred significantly in certain patients, expecially those with major anatomic abnormalities, during a six-week follow-up period. the incidence of drug reactions was low.	1975	1100295
amino-acid composition of the covalent rigid-layer lipoprotein in cell walls of proteus mirabilis.	cell walls of proteus mirabilis in the stationary phase of growth contain a lipoprotein in covalent linkage to peptidoglycan and probably also in free form in the outer membrane. the protein moiety of this lipoprotein is composed of about 50 amino acids and has an approximate molecular weight of 5500. the proteus lipoprotein has glycine and phenylalanine as specific components which are not present in lipoproteins of other enteric bacteria. treatment of the peptidoglycan-lipoprotein complex of p ...	1975	1100405
rapid identification of swarming proteus using the pathotec ornithine decarboxylase test strip.	the pathotec ornithine decarboxylase test strip was evaluated for use in identification of swarming proteus. all 181 strains tested were accurately identified within 4 h.	1975	1100667
transduction of a proteus vulgaris strain by a proteus mirabilis bacteriophage.	only proteus vulgaris strain pv127 out of many p. vulgaris, p. morganii and providence strains was transduced to kanamycin resistance by high-frequency transducing variants, 5006mhftk and 5006mhftak, of phage 5006m, a general transducing phage for p. mirabilis strain pm5006. the phages adsorbed poorly to strain pv127 and did not form plaques. the transduction frequency of pv127 by these phages was 5 x 10(-8)/p.f.u. adsorbed. phage 5006m increased the transduction frequencies. abortive transducta ...	1975	1100773
extensive segments of the escherichia coli k12 chromosome in proteus mirabilis diploids.	various escherichia coli k12 hfr donors transfer at low frequency portions of the e. coli genome to proteus mirabilis. by remating such proteus hybrids with the same or a different e. coli hfr strain, other genetic characters could be added to yield diploid proteus hybrids which contained more than 30 percent of the e. coli genome. the extent of the e. coli genetic material in these unstable proteus diploid hybrids included segments with the following selected markers: gal, lac, ara, mel, mtl, a ...	1975	1101034
septic arthritis in children.	when septic arthritis involves the hip, the prognosis is much worse than with any other joint. approximately 50 per cent of the results were unsatisfactory with hip involvement compared to 12 per cent unsatisfactory results with involvement of the other joints. the erythrocyte sedimentation rate is a much more helpful diagnostic test than the leukocyte count or differential cell count. the most important prognostic factors are the duration of symptoms prior to treatment, a penicillinase-producin ...	1975	1101133
bacteremia in a general hospital. a prospective study of 102 consecutive cases.	a prospective clinical-bacteriological study of 102 consecutive cases of confirmed bacteremia at a copenhagen city general hospital was carried out during 5 months of 1973 with special concern given to focus of infection and acquisition of microorganisms. valid positive cultures were obtained from 7.2 patients per 1000 admissions. 50 of the 102 bacteremias were by all probability acquired in the hospital, mainly due to transurethral manipulations or intravenous lines. pneumonia and hepatobiliary ...	1975	1101372
[swarming phenomenon of an aeromonas spec (author's transl)].	a genuine swarming phenomenon, such as has previously been known to occur in proteus, bacillus and clostridium species only, was observed in an aeromonas species. fig. 1 shows the terraced swarming zones of the aeromonas species on nutrient agar. the swarming rate, expressed as the growth of the swarming zone per time unit, was measured to be 70-120 mum/min on blood agar at 30 degrees c. the swarming could be inhibited by incubation at 37 degrees c (table 2), by low saline concentrations (table ...	1975	1101579
effect of surfactants on antibiotic resistance.	the effectiveness of surfactants as potentiators of antibiotic activity on several resistant strains of bacteria, selected from clinical sources and laboratory collections, was studied using a tube dilution assay. bacterial strains included members of the enterobacteriaceae and staphylococci. cetyltrimethylammonium bromide (ctab), tween 80 (tw80), a mixture of n-alkyldimethyl betaines (l14), and alpha-(2,4,5-trichlorophenoxy) propionic acid (tcp) were tested in combination with pencillin g (peng ...	1975	1101823
potent combinations of beta-lactam antibiotics using the beta-lactamase inhibition principle.	several penicillins known to be stable to enterobacterial beta-lactamases were tested in combination with beta-lactamase-sensitive penicillins and cephalosporins in a turbidimetric system. nafcillin was found to be the best beta-lactamase inhibitor amongst agents presently available commercially, but the related, new semi-synthetic penicillin brl 1437 (2-isopropoxy-1-naphthylpenicillin) was consistently found to be superior. using 103 ampicillin-resistant coliform bacilli and antibiotic levels a ...	1975	1102266
the isolation of two different lipopolysaccharide fractions from various proteus mirabilis strains.	four distinct proteus mirabilis strains were extracted by the phenol/water procedure. after ultracentrifugation of the dialyzed water phase, the pelleted lipopolysaccharide was purified and analyzed. the sugar composition of this lipopolysaccharide fraction i was similar for all four strains, containing only small amounts of strain-specific constituents. a second lipopolysaccharide fraction was isolated from the supernatant above (termed l1 fraction) after removal of nucleic acids. deae-cellulos ...	1975	1102309
identification of ribitol phosphate as a constituent of the lipopolysaccharide from proteus mirabilis, strain d52.	a polyol was released from the lipopolysaccharide of proteus mirabilis, strain d52, during alkaline hydrolysis and its phosphate ester was isolated after acid hydrolysis. this polyol has been identified as ribitol by comparison of the free polyol, its phosphate ester and its anhydro derivative formed after acid treatment with authentic xylitol, d- and l-arabitol, ribitol and their corresponding derivatives on paper and gas-liquid chromatography.	1975	1102310
[studies on the in vitro effects of cephalothin and gentamicin, alone and in combination, on proteus mirabilis and enterococci (author's transl)].	a combined antibiotic therapy is only useful in a few precisely defined clinical pictures where testing of the chemotherapeutics administered is required to determine their characteristics of action (antagonism, indifference, synergism) on the isolated organism. for the initial therapy of critical acute infections, simultaneous administration of cephalothin and gentamicin proved to be valuable. in the present study, the efficiency of these chemotherapeutics alone and in combination was investiga ...	1975	1102455
the significance of cardiac arrhythmias in the septic patient.		1975	1102867
susceptibility of a hybrid plasmid to excision of genetic material.	a 5 megadalton segment of dna carrying a gene for kanamycin resistance from r447 b (a plasmid of group n of molecular weight 33 megadaltons) has been inserted into plac (a plasmid of the a--c complex of molecular weight 101 megadaltons) to produce the recombinant plasmid plac-r447 b (coetzee, 1974). the recombinant plasmid is a typical member of the a--c complex except that entry of an n group plasmid into a plac-r447 b+ recipient frequently leads to the loss of 5 megadaltons of dna (including t ...	1975	1102953
therapeutic guidelines in the management of urinary tract infections and pyelonephritis.		1975	1103409
bacteremia arising from the urinary tract.		1975	1103413
reduction of azo food dyes in cultures of proteus vulgaris.	1. rates of reduction of a number of azo food dyes were measured in anaerobic cultures of proteus vulgaris. the rates of colour loss were found to be zero order under conditions in which the concentration of viable cells remained constant. 2. a significant increase in the rate of reduction followed the onset of cell mortality. 3. the zero-order rates correlate with the redox potentials of the dyes. a mechanism consistent with these observations involes an extracellular non-enzymic reducing agent ...	1975	1103488
[dependence of various antigen formation of proteus mirabilis strain 1095/67 growing on minimal nutrient media].	proteus mirabilis strain 1095/67 has been cultivated in surface culture on different minimal media, which were composed either of single amino acids or combinations of several amino acids without or with stepwise addition of other c-sources up to the complete medium. we found a direct dependence of the formation of the various antigens (moving to the cathode, to the anode, or not moving) on the composition of the medium. certain amino acids (ala, glu, asp. ser) elicit only parts of the antigenic ...	1975	1103489
[modification of problem pathogens in chronically infected bladders through irrigation and instillation agents].		1975	1103518
bacterial flora in relation to cataract extraction. iii. postoperative flora.	the conjunctival flora of 499 patients operated for cataract was studied on the 4th and 7th postoperative days and compared with the flora examined previously on admission to the hospital and at the time of surgery (fahmy et al. 1975b, c). antibiotics had been administered approximately 18 hours before operation, at the conclusion of surgery, and then on the 4th postoperative day after the cultures had been taken. after a significant fall in incidence, including all kinds of bacteria at the time ...	1975	1103562
resistance to beta-lactam antibiotics proteus strains.	a total of 218 proteus strains isolated from clinical sources were tested for their susceptibility to three penicillins and two cephalosporins. the ability to beta-lactamase production was examined in 36 of these strains. proteus mirabilis strains were generally more susceptible to cephalosporins than to penicillins, whereas indole-positive protei were almost uniformely resistant to cephalosporins as well as to ampicillin and benzylpenicillin but susceptible to carbenicillin. fairly good correla ...	1975	1103580
enumeration of high numbers of bacteria using hydrophobic grid-membrane filters.	printing a wax grid on a conventional membrane filter yields a device functioning as a most probable number apparatus (mpn), used at a single dilution but with a very large number of growth compartments (e.g., 3,650). by restraining the lateral spread and confluence of colonies, the hydrophobic grid-membrane filter (hgmf) allows growth- or colony-forming units (gu) to be resolved at levels far above those which produce an uncountable lawn on a conventional membrane filter. it also eliminates the ...	1975	1103728
matrix calculi.	matrix calculi are an uncommon form of urinary tract concretion. they must be considered in the differential diagnosis of a radiolucent mass within the renal collecting system or ureter. the clinical and radiographic features of three cases are presented and the literature of matrix calculi is reviewed.	1975	1104035
septic shock.	the problems associated with septic shock are highlighted, including those which arose during a 3-year prospective study. mortality in the first year of the study was 71 per cent, falling to 38 per cent in the third year. the reasons for this fall are detailed. the pattern of survival times changed over the 3 years, giving rise to the longer term complications such as stress bleeding, multiple organ failure and superadded infection.	1975	1104040
further investigations of proteus mirabilis lipopolysaccharides.		1975	1104102
attempt to enhance resistance to infection in 6-mercaptopurine treated mice by lysozyme administration and immunization with escherichia coli o86 antigen.	long-term immunosuppressive therapy of mice with 6-mercaptopurine (6-mp) for 2 and/or 3 weeks results in partial lethality, decrease of total leukocyte count, of serum lysozyme level and in bacteremia. the adverse effect of 6-mp treatment could not be prevented by lysozyme administration; immunization with escherichia coli o86 antigen further increased the lethality of 6-mp in mice. the results stress the potential danger of immunization with bacterial antigens during immunosuppressive therapy.	1975	1104427
classification of cephalosporins by their antibacterial activity and pharmacokinetic properties.		1975	1104556
selective medium for growth of proteus.	a medium containing heart infusion agar supplemented with bile salts, lithium chloride, sodium thiosulfate, and sodium citrate was developed for the selective growth of proteus.	1975	1104657
specialized transduction of a leucine marker by proteus mirabilis phage 5006m.		1975	1104770
[studies on the disc method for the determination of bacterial sensitivity to sulfobenzylpenicillin (author's transl)].	the mic''s of sulfobenzylpenicillin (sb-pc) were determined by the two-fold serial agar-dilution method for 108 bacterial strains of 21 species. the diameters of inhibition zones of these bacterial strains by the 30 mug and 200 mug sb-pc discs were also measured. the relation between the mic and the diameter of the inhibition zone was found to be expressed as a primary regression line in all cases of the conventional method (cultured for about 16 hours), delayed assay method (cultured for about ...	1975	1104912
[in vitro examination on antibacterial activities of broad-spectrum antibiotics against gram-negative clinical isolates (author's transl)].	in vitro studies were undertaken on clinically isolated strains of various bacteria to examine the antibacterial activity of ampicillin (ab-pc), carbenicillin (cb-pc), sulbenicillin (sb-pc) cephalothin (cet), cefazolin (cez) and gentamicin (gm). fifty three % of escherichia coli strains 53.3% of citrobacter sp., 80% of proteus mirabilis, 42.9% of morganella and 80% of bacteroides sp. were susceptible (mic being not higher than 12.5 mug/ml) to ab-pc. the eight other species were not so susceptibl ...	1975	1104913
[sensitivity of bacteria inducing urinary infections to 3 drugs (amoxicillin, ampicillin and cephalexin) and clinical efficacy of amoxicillin (author's transl)].	mic of amoxicillin (ampc), ampicillin (abpc) and cephalexin (cex) against bacteria detected from the patients suffering from urinary infections was determined and the clinical efficacy of ampc was examined. as the result of determining mic of ampc against the detected escherichia coli, 85.4% showed the value of less than 6.25 mcg/ml. ampc and abpc seem to be well correlated with each other regarding mic, and ampc showed 1 approximately to 2 stage lower concentration than cex. in connection to cl ...	1975	1104914
morbidity, age and sex distribution, recurrences and renal scarring in symptomatic urinary tract infection in childhood.		1975	1104973
r-factors in urinary tract infection.		1975	1104976
transformation of lymphocytes in patients with certain bacterial infections.	the state of cell-mediated immunity was measured by the morphological method of lymphocyte transformation with and without pha, in a group of 56 patients with bacterial infections and in a group of healthy controls. the patients were divided into three subgroups according to the aetiology: 1. patients with gram-positive infections, 2. patients with gram-negative infections, and 3. mixed infections. the transformation values with pha were significantly (t-test) higher in the gram-positive subgrou ...	1975	1105129
characterization of a stable spheroplast type l-form of proteus mirabilis d 52 as cell envelope mutant. i. isolation, growth characteristics, biochemical activities, and sensitivity to bacteriophages.	a stable spheroplast type l-form could be isolated by transferring 627 single colonies and 195 agar blocks with several colonies of unstable l-forms of proteus mirabilis d 52 on agar media without supplements of penicillin. the l-form grows well on complex and synthetic agar media, however, it failed to grow in any of the liquid media which have been proved. with one exception (formation of acid from maltose) the l-form shows the same bioche mical activities like the parent rod-shaped bacterium. ...	1975	1105990
[some problems of nomenclature and taxonomy of the enterobacteriaceae].		1975	1106093
reduction of tetrathionate, trithionate and thiosulphate, and oxidation of sulphide in proteus mirabilis.	the reductase catalyzing the reduction of tetrathionate and thiosulphate in proteus mirabilis is also concerned with the reduction of trithionate and the oxidation of sulphide. tetrathionate is reduced to thiosulphate, thiosulphate to sulphite and sulphide, and trithionate is reduced to thiosulphate plus sulphite. the oxidation of sulphide in cell-free extracts proceeds most likely to polysulphanes or to elemental sulphur, depending on the conditions. the kinetics of the reduction of tetrathiona ...	1975	1106343
[synergism of colistin and sulfonamide in proteus species (author's transl)].	in agar diffusion testing of proteus mirabilis strains sensitive to sulfonamide a synergistic effect of colistine (c) and sulfonamide (s) was demonstrated. by quantitative evaluation these results were confirmed in 100 strains of proteus mirabilis and 100 strains of indol-positive proteus spp. using broth dilution method. combining 1 part c with 10 parts s the mean increase in sulfonamide sensitivity was enhanced fourfold. increasing the inoculum sensitivity of proteus against the combination of ...	1975	1106440
[peritonitis in infants, small children and childhood].		1975	1106963
[study of the transferable factors of antibiotic resistance in the enterobacteria isolated at the regional hospital center of nantes].	characteristics of transferable resistance of 72 entero-bacteriaceae resistant to one more antibiotic, isolated from february to september 1972, showed that this was common. multi-resistant strains permit one to obtain transfer of various characteristics either alone or together in 76 per cent of cases, whereas strains with less than three characteristics, transferred in only 9 per cent of cases. the transfers were uncommon in the case of proteus compared with other enterobacteriaceae and, in pa ...	1975	1108714
sex-related incidence in proteus infection of the urinary tract in childhood.	over a 2-year period 80% of children found to have significant proteus bacteriuria were boys. the organism was isolated from the prepuce in 30% of normal boys and 32% of those with balanitis. proteus urinary tract infection should be carefully confirmed and proved cases thoroughly investigated.	1975	1108808
[recent studies on the in vivo and in vitro activity of gentamicin].	the effect of gentamycin was investigated at the university of modena phthisiology and respiratory diseases department. in vitro activity against most pathological gram-positive and gram-negative bacteria was observed. a dose of 4-5 mg/kg proved very effective in cases of bacteria-induced bronchopneumopathy. the drug was also active against penicillin-resistant staphylococci and gram-negative bacteria with a known resistance to ordinary antibiotics.	1975	1113913
antibiotics in surgery.		1975	1115614
tryptophan biosynthetic pathway in the enterobacteriaceae: some physical properties of the enzymes.	several physical properties of the first four enzymatic activities of the tryptophan pathway were examined using gel filtration and ion exchange chromatography. five different patterns were noted. differences in the anthranilate synthetase (as) and phosphoribosylanthranilate transferase (prt) defined these patterns. in all the organisms studied phosphoribosylanthranilate isomerase and indoleglycerol phosphate synthetase co-eluted from both diethylaminoethyl-cellulose and g-200 and thus probably ...	1975	1116988
a transvesical approach to total seminal vesiculectomy: a case report.		1975	1117507
[necrotic and infected tubal cancer. ileo-sigmoid fistula].		1975	1118696
effects of procedural variations on the activity of aminoglycosides in vitro.	am j clin pathol 63:438-445, 1975. the effects of procedural variations on the activities of gentamicin, tobramycin, sisomicin, kanamycin, and amikacin in vitro were evaluated using 134 clinical isolates. in broth dilution studies, a change in assay medium from brain-heart infusion broth to mueller-hinton broth resulted in significant changes in minimal inhibitory concentrations in 36% (242 of 670) of assays. a change in the bacterial population size utilized in broth dilution studies resulted i ...	1975	1119441
[effect of carbenicillin and its combination with prodigiozan and lysozyme on the course of an experimental inflammatory process of proteus etiology].	biological properties of 142 proteus strains isolated from patients were studied. sensitivity of proteus to ii antibiotics was tested. the isolates were resistant to most of the antibiotics. the highest number of the isolates was sensitive to ampicillin (77.1 minus or plus 7.16) and especially to carbenicillin (82.6 plus or minus 6.16). this provided the use of carbenicillin for the treatment of experimental septicemia in albino mice and wound processes in rabbits with proteus complications. the ...	1975	1119792
the tryptophanase from proteus rettgeri: sulfhydryl groups in the holo- and apo-enzyme preparations.		1975	1123078
[intrageneric o-antigenic relations of providencia bacteria].	the authors present literature and personal data on the intragenera o-antigenic relations of the strains of a collection of bacteria belonging to providencia genus, including standard strains of 53 serological o-groups whose antigenic interrelations were studied serologically in the tests of agglutination and adsorption of agglutinins. experimental results confirmed the presence of unilateral relations by the o-antigen between the serological groups 01-021, 03-021 and bilateral relations between ...	1975	1124619
infections in total hips secondary to a primary source elsewhere.	this is a report of 3 cases in which a primary infection in a site other than a total hip led to infection in the hip itself. one hip infection appeared to arise in a tooth abscess, a second in the urinary tract, and one from the respiratory tract. all infections resulted in the necessity of removing the components of the total hip. it is suggested that patients who have had previous total hip replacement should be warned to consult their physician when the possibility of an infection is present ...	1975	1126095
in vitro antibacterial activity of amikacin, a new aminoglycoside, against clinical bacterial isolates from children.	four hundred and fifty-eight clinical bacterial isolates from a children's hospital were examined for antibiotic susceptibility to amikacin (bb-ks) in comparison with a number of other antibiotics by the disk diffusion and agar dilution methods. the wide spectrum of activity of amikacin against gram-negative bacteria was confirmed; it included e. coli, proteus species, enterobacter species, and pseudomonas aeruginosa. staphylococci were highly sensitive, but other gram-positive bacteria tested w ...	1975	1127131
experience with detailed surveillance of nosocomial infection.	infection rates have been determined in a 332 bed university hospital using an efficient surveillance program. this computerized program analyzed, summarized and returned infection reports in six days. the efficiency rate of this system was 80 per cent as determined by prevalence survey. the mean nosocomial infection rate for the 12 month study period was 10.8 per cent. neurology, medicine, neurosurgery, surgery and urology ahd the highest attack rates. urinary tract infections composed 44 per c ...	1975	1129686
nephrotoxicity of combined cephalothin-gentamicin regimen.	two patients developed acute tubular necrosis, characterized clinically by acute oliguric renal failure, while they were receiving a combination of cephalothin sodium and gentamicin sulfate therapy. patients who are given this drug regimen should be observed very carefully for early signs of nephrotoxicity. high doses of this antibiotic combination should be avoided especially in elderly patients. patients with renal insufficiency should not be given this regimen.	1975	1130930
effects of induced pinocytotic activity and extreme temperatures on the morphology of golgi bodies in amoeba proteus.	the morphology of the golgi apparatus of amoeba proteus can be influenced by substances inducing pinocytotic activity as well as by extreme temperatures. during the ingestion of a solution of 0.5% egg white the number of golgi bodies decreases from 100% measured in control cells to 82% measured in cells showing induced pinocytosis. simultaneously the ratio of the surface area of the cisternae at the proximal face to that of the vesicles at the distal face of single dictyosomes remains constant ...	1975	1131858
microfibrillar structures in the nucleus and cytoplasm of amoeba proteus.	the presence of microfibrillar structures in the nucleus and cytoplasm of amoeba proteus has been described after glutaraldehyde and osmium fixation. the possible roles of cytoplasmic microfibrils in the contraction process of amoeba and nuclear microfibrils in the formation of the honeycomb nuclear lamina are discussed.	1975	1133571
activity of three aminoglycosides and two penicillins against four species of gram-negative bacilli.	three aminoglycoside antibiotics and two penicillins were compared for their in vitro activity against 60 isolates of serratia, pseudomonas, proteus mirabilis, and indole-positive proteus sp. testing was done by the agar dilution method using mueller-hinton broth solidified with 1.5% agar. the activity of amikacin, aminodeoxybutirosin, and gentamicin against proteus and pseudomonas, as related to their peak blood levels, showed no significant differences. amikacin was the most active against ser ...	1975	1137369
bl-s 640, a cephalosporin with a broad spectrum of antibacterial activity: properties in vitro.	bl-s 640 was evaluated in vitro by comparison with cephalothin, cephaloridine, cefazolin, and cephalexin. the new compound was more active than the control cephalosporins against most major gram-negative and some gram-positive species. moreover, its antibacterial spectrum included strains of enterobacter, proteus morganii, p. rettgeri, and providencia stuartii, species generally resistant to the other cephalosporins. bl-s 640 was an effective bactericidal agent for strains of various species of ...	1975	1137381
susceptibility of clinical isolates of enterobacteriaceae to bl-s640, a new oral cephalosporin.	the in vitro activity of bl-s640, a 7-(2-aryl-2-aminoacetamido)-3-(heterocyclic-thiomethyl) cephalosporin, was evaluated against 338 clinical isolates of enterobacteriaceae in comparison with ampicillin, cephalothin, cefazolin, and cephalexin. against escherichia coli, bl-s640 was as active as cefazolin and more active than ampicillin, cephalothin, and cephalexin. bl-s640 was as effective as the other cephalosporins tested and far more active than ampicillin against klebsiella and was more activ ...	1975	1137392
trimethoprim-sulfamethoxazole in chronic bronchitis.	authenic tracheobronchial secretions/exudates (tbse) were aspirated under direct vision via a sterile catheter passed through a fiberoptic bronchoscope from patients with chronic obstructive pulmonary disease complicated by chronic bronchitis. tbse, saliva and blood were obtained during long-term administration of trimethoprim-sulfamethoxazole (tmp-smx) and were assayed for drug content. before and during treatment tbse were cultured qualitatively and quantitatively for aerobic and anaerobic bac ...	1975	1137833
amoeba proteus: the nuclear periphery.	this study extends previous work on the nuclear envelope and associated structures. it illustrates that the cylindrical structures of the honeycomb lattice are not attached to the nuclear envelope, although generally perpendicular and closely apposed to it, and that there is a complex arrangement of fibrillar material between the cylinders of the lattice. the relationship of nuclear helices to these structures is described and the possible mode of their transfer from nucleus to cytoplasm is disc ...	1975	1137851
canine polypoid cystitis.	the clinical, laboratory, and radiographic characteristics of polypoid cystitis in 2 dogs were similar to those commonly associated with neoplasms of the urinary bladder. gross appearance of the polyps did not permit differentiation between inflammation and neoplasia; microscopic examination of excised tissue was required to establish a definitive diagnosis. following surgical extirpation of the polyps, remission of clinical signs was induced by prolonged antibacterial therapy.	1975	1141031
oriented thick and thin filaments in amoeba proteus.	actin and myosin filaments as a foundation of contractile systems are well established from ameba to man (3). wolpert et al. (19) isolated by differential centrifugation from amoeba proteus a motile fraction composed of filaments which moved upon the addition of atp. actin filaments are found in amebas (1, 12, 13) which react with vertebrate heavy meromyosin (hmm), forming arrowhead complexes as vertebrate actin (3, 9), and are prominent within the ectoplasmic tube where some of them are attache ...	1975	1141376
[change of the hereditary properties of amoeba proteus during micrurgic intervention at the time of mitosis (metaphase ane early anaphase)].	studies have been made on viability and hereditary properties of the progeny of amoebae after micrurgical coercions (sectioning of cells, suction of cytoplasm) during metaphase and early anaphase. the progeny of the fragments as well as of the cells with the reduced bulk of the cytoplasm exhibits unusual methionine resistance. possible mechanism of the observed phenomemon are discussed.	1975	1145767
faecal stasis and bacteriuria: experimental research in rats.		1975	1145908
acute postoperative wound complications after gastric surgery for morbid obesity.	the acute postoperative wound complications of 225 morbidly obese patients undergoing gastric bypass were compared against the complications observed in 225 normal-sized individuals who underwent elective gastric resection for peptic ulcer disease. not only were there more wound infections (8.9 percent to 5.3 percent) in the obese population, but these infections inflicted more serious complications and a significantly increased hospital stay. while the exact cause of the increase in infections ...	1975	1147403
the tryptophanase from proteus rettgeri, improved purification and properties of crystalline holotryptophanase.	the inducible tryptophanase (l-tryptophan indole-lyase (deaminating) ec 4.1.99.1) was crystallized in holoenzyme from the cell extract of proteus rettgeri. the purification procedure included ammonium sulfate fractionation, heat treatment at 60 degrees c, deae-sephadex and hydroxylapatite column chromatographies. crystallization was performed by the addition of ammonium sulfate to the purified enzyme solution containing 20% (v/v) glycerol, 0.1 mm pyridoxal phosphate and 10 mm mercaptoethanol. th ...	1975	1148216
proceedings: bacteriology of ileal conduits.		1975	1148640
specialized transduction of kanamycin resistance in a providence strain.	properties of a transducing system with a phage able to transduce a kanamycin-resistance marker of the t compatibility group plasmid r394 at a frequency of 2 times 10(-2)/plaque-forming unit adsorbed are described. the phage was detected in providence strain p29 transduced to kanamycin resistance by providence phage pl25 grown on this strain harbouring the r factor. four p29 transductants, specially selected at the lowest multiplicities of infection of the high frequency transducing (hft) phage, ...	1975	1151340
experimental bacterial endocarditis. iv. structure and evolution of very early lesions.	the vegetations of experimental sterile and bacterial endocarditis in rabbits were studied using light, immunofluorescent and electron microscopy. at an early stage, both lesions were composed chiefly of masses of platelets supported in a scaffolding of fibrin strands. in previous studies, this structure has often been described merely as "fibrin". after i.v. injection of thorotrast, sterile vegetations showed remarkable accumulations of mononuclear phagocytes containing this substance, on surfa ...	1975	1151519
the sex variable in childhood urinary-tract infection.	sex differences in childhood urinary-tract infection have been looked for by reviewing the medical records of all patients who were admitted to one medical centre during a certain time period. there were 240 patients; 26 males and 214 females, all under 14 years of age. the disease in boys-as compared with that in girls-was found to be characterized by an earlier onset, a shorter delay in diagnosis, and a shorter duration; but a higher frequency of malformations, a greater number of rehospitaliz ...	1975	1155077
new serotypes of morganella morganii.	on the basis of 8 new o and 11 new h antigens determined in 22 strains, the morganella morganii antigenic schema was supplemented with 8 serogroups (o35-o42) and 13 serotypes. four strains belonged to o groups described earlier and 2 strains contained new o antigens in combination with known o antigens. known h antigens were present in one strain as a single factor and in one strain as combination of two factors. new h antigens were demonstrated in 5 serotypes in combination with known h antigen ...	1975	1155231
[bacteriology and serology of pyelonephritis in children (author's transl)].	a short review is made on the bacterial pathogenicity factors related with urinary-tract invasion and renal damage in pyelonephritis. microbiological findings obtained after a revision of 14,181 quantitative cultures carried our in the last nine years on children under 7 years old are discussed. "e. coli" is implicated in almost a half of positive cultures; "k pneumoniae" seems to be specially related with urinary infections of premature and newborn infants (20-30% of the bacterial positivities ...	1975	1155866
selective effects of enucleation and transfer of heterologous nuclei on cytoplasmic organelles in amoeba proteus.	the ultrastructural changes in the cytoplasm of lethal hybrids obtained by nuclear transplantation between different strains of amoeba proteus were compared with those of enucleated amebae. it was found that, whereas the golgi complex and glycocalyx degenerated first in enucleated cells, mitochondria and endosymbiotes became abnormal first in the hybrids. the selective effects are attributed to the presence of nucleic acids in the mitochondria and endosymbiotes and hence to the different inter ...	1975	1159642
in vitro evaluation of bl-s640, a new oral cephalosporin antibiotic.	bl-s640, a new oral cephalosporin analogue, was evaluated in vitro against 102 gram-negative and 80 gram-positive bacteria. the antimicrobial spectrum was similar to that of previous cephalosporin analogues. good antimicrobial activity against strains of escherichia coli, klebsiella, staphylococci, and streptococci was demonstrated. relatively poor activity and/or resistance was noted among most strains of proteus, providencia, pseudomonas, and serratia. in comparative studies bl-s640 had better ...	1975	1167042
characterization of hydrogen sulfide-producing bacteria isolated from meat and poultry plants.	a survey of the types of aerobic organisms able to produce h2s on peptone iron agar (levin, 1968), and commonly occurring in meat and poultry plants, revealed that these could be divided into four distinct groups. the ability of representative strains of each type to grow at low temperatures and cause off-odors on chicken muscle was examined. the results are discussed in relation to the role of these organisms in the psychrophilic spoilage of meat and meat products.	1975	1167774
antimicrobial activities of 81.723 hfu, a new pleuromutilin derivative.	the new pleuromutilin derivative 81.723 hfu is extremely active against gram-positive organisms such as streptococci, staphylococci, and against mycoplasmas. a number of shigella, klebsiella, and escherichia coli strains were also found to be quite susceptible to this new agent, whereas other gram-negative organisms like pseudomonas aeruginosa, proteus species, and alcaligenes faecalis proved to be naturally resistant to 81.723 hfu. the new compound acts bacteriostatically. bactericidal effects ...	1975	1170807
anicteric carbenicillin hepatitis. eight episodes in four patients.	carbenicillin disodium was temporally associated with eight episodes of a mild reversible anicteric hepatitis characterized by nausea, vomiting, and a tender, somewhat enlarged liver. serum glutamic and oxaloacetic transaminase as well as alkaline phosphatase levels rose, but serum bilirubin values remained normal. there usually were no signs of concomitant allergy to penicillin, and other penicillins could be given subsequently without ill effects. biopsy specimens of the liver showed spotty li ...	1975	1173185
cytoplasmic filaments and cellular wound healing in amoeba proteus.	the flexibility and self-healing properties of animal cell surface membranes are well known. these properties have been best exploited in various micrurgical studies on living cells (2, 3), especially in amoebae (7, 20). during nuclear transplantation in amoebae, the hole in the membrane through which a nucleus passes can have a diameter of 20-30 mum, and yet such holes are quickly sealed, although some cytoplasm usually escapes during the transfer. while enucleating amoebae in previous studies, ...	1975	1176533
isolation and characterization of a lactose-positive strain of proteus morganii.	the characterization of a lactose-positive proteus morganii is presented. the increased incidence of such atypical microorganisms emphasizes the need for a thorough examination of escherichia coli-like colonies by clinical microbiologists.	1975	1176589
biotypes of proteus rettgeri.	examination of 729 isolates of proteus rettgeri showed that 674 reacted positively in tests for phenylalanine deamination, indole production, growth on citrate, and acid production from meso-inositol, and negatively for l-ornithine decarboxylation and acid production from lactose, maltose, d-xylose, and l-arabinose. only 51 isolates differed in one, and four differed in two of these ten reactions, which were taken as the core characteristics of the species. on the basis of additional tests (acid ...	1975	1176597
use of bile-esculin agar for rapid differentiation of enterobacteriaceae.	bile-esculin agar has been used for several years for the presumptive identification of group d streptococci. all members of the enterobacteriaceae family will also grow on this medium, but only certain ones can hydrolyze esculin to 6,7-dihydroxycoumarin, which reacts with iron to produce a characteristic blackening of the medium. one thousand and six cultures from clinical specimens representing 20 genera were isolated and identified. heavy inocula from fresh pure culture isolates on heart infu ...	1975	1176613
evaluation of tyrosine medium for the identification of enterobacteriaceae.	use of the tyrosine medium in the identification of members of the family enterobacteriaceae form the basis of this paper. six hundred and twenty-three strains were tested for their property of tyrosine degradation. three hundred and seventy-two strains were positive in 24 h and an additional eight strains were positive in 48 to 72 h. these positive strains consisted of all 344 strains of the proteus-providencia group, all 25 strains of citrobacter diversus, and three strains of atypical c. freu ...	1975	1176617
motility-indole-lysine-sulfide medium.	a medium designed for the detection of motility, indole, lysine decarboxylase and deaminase reactions, and h2s production was devised and evaluated. results, using 157 strains of enteric pathogens, were in agreement with reference methods. when 300 isolates from fecal cultures were screened using this medium, shigella was easily differentiated from escherichia and more of the proteus species, especially p. morganii, could be eliminated from further study.	1975	1176633
clinical observations of scrub typhus on penghu (the pescadores islands).	between may and september 1973, 68 cases of scrub typhus in chinese military personnel on the pescadores islands were studied. the common symptoms and signs were fever, chills, headache, eschar, myalgia, and lymph node enlargement. most eschars were located in the axilla, waist, groin and genitals, and neck. these lesions were painless and not noticed by the patients themselves. regional lymph node enlargement at the site of eschar drainage was common. relative bradycardia with fever was observe ...	1975	1179479
accuracy of kirby-bauer susceptibility tests read at 4, 8, and 12 hours of incubation: comparison with readings at 18 to 20 hours.	disk diffusion antibiotic susceptibility tests as performed by the hospital diagnostic microbiology laboratory were read at 4, 8, and 12 h of incubation and compared to the traditional 18-h readings. both the zone size in millimeters and a judgement of susceptible or resistant were recorded by the investigator at each time interval for each drug tested against the various clinical isolates. considerable variation of zone sizes existed for certain organisms (e.g., staphylococci and proteus) and c ...	1975	1180540
septic arthritis in systemic lupus erythematosus.	five patients with systemic lupus erythematosus (sle) developed septic arthritis. neisseria gonorrheae, staphyloccocus aureus, proteus and escherichia coli were the offending bacterial organisms. predisposing factors included systemic and local corticosteroids, aseptic necrosis of bone and synovitis due to sle. the diagnosis was made by culture of the organisms from the synovial fluid. three patients recovered without residual joint damage, one required corrective arthroplasty and one died from ...	1975	1185738
comparative in vitro activity and clinical pharmacology of ticarcillin and carbenicillin.	the in vitro activity and human pharmacology of ticarcillin, a semisynthetic penicillin more active than carbenicillin against pseudomonas, were compared. there has been no increase in resistance to ticarcillin of pseudomonas strains over the past 5 years, but resistance of indole-positive proteus and serratia strains has been documented. after intramuscular (i.m.) injection of 1 g of ticarcillin, mean peak levels occurred at 1 h (26.9 mug/ml) with a decline over 6 h (6.8 mug/ml). serum half-lif ...	1975	1190752
[therapeutic effect of sulfobenzyl-penicillin (sb-pc) on the concentration of sb-pc in human bile (author's transl)].	sulfobenzyl-penicillin (sb-pc) is currently being investigated for use in man. the purpose of this study was to evaluate effect of sb-pc on salmonella typhosa and biliary excretion of sb-pc in disease of the biliary tract. 1) clinically, typhoid carriers without cholelithiasis were initiated with 4.0 g/day of sb-pc. stool and bile became negative for salmonella typhosa 14 days after initial treatment. 2) in typhoid carriers with cholelithiasis, salmonella typhosa were not isolated from bile, wal ...	1975	1195516
on the nature of hyaline zones in the cytoplasm of amoeba proteus.	investigations with the nomarski dic (differential interferece contrast) microscope and the electron microscope on the nature of hyaline zones in the cytoplasm of amoeba proteus revealed that these regions represent pure ground cytoplasm. differences between specimens 1) treated with 2% ethanol, 2) released from high hydrostatic pressure or 3) preincubated at 35 degrees c for 30 minutes could not be observed. only dying cells undergoing lysis contained a watery solution within the zones of hyali ...	1975	1196142
four hour-test for the identification of enterobacteriaceae.	a set of 12 rapid biochemical tests--lysinedecarboxylase, ornithinedecarboxylase, beta-galactosidase, urease, hydrogensulphide, indole, acetoin, deoxyribonuclease, esculin, mannitol, raffinose and sorbitol--were selected from an original set of 13 tests and were found to give 98% accurate reactions within 4 hrs of incubation for the identification of bacteria belonging to enterobacteriaceae. this set permits identification on the genus and/or species level for escherichia, shigella, citrobacter, ...	1975	1196260
[clinical x-ray characteristics of acute suppurative destructions of the lungs of a nonstaphylococcal nature in children].	the authors conducted complex clinico-roentgenological and immuno-bacteriological studies in 63 children, aged from 14 days to 14 years, with acute suppurative destructions of the lung, complicated with the development of pyothorax. as a result of these investigations, it was found that clinico-roentgenological symptomatics in children with acute suppurative destructions of the lung of the non-staphylococcal nature (proteus, pyocyanic bacillus and others) show evident peculiarities and differ fr ...	1975	1198828
new thoughts concerning xanthogranulomatous pyelonephritis (x-p).	a clinical and roentgenographic analysis of 13 patients with pathologically proved xanthogranulomatous pyelonephritis (x-p) has demonstrated that many previously accepted truisms associated with this disease may not be valid. as a result of this study it is suggested that x-p: 1. does have a prominant female distribution. 2. may arise relatively acutely. 3. can be associated with a well-functioning kidney. 4. may destroy the kidney and collecting system. 5. does not demonstrate neovascularity. 6 ...	1975	1200208
[etiology of acute suppurative destructive pneumonias in children].	clinical, immunological and bacteriological studies were carried out in 63 children with the so-called staphylococcus destruction of the lungs. it was shown that in some of the cases destructive process in the lungs, along with the pathogenic staphylococcus, could be caused by the gram negative bacteria (proteus, bac. pyocyaneus, etc.). it was found that in children of different age groups the titre of antistaphylococcus antibodies up to 0.5 au/ml was normal and pointed to the absence of any inf ...	1975	1202883
[differentiation of proteus-providencia group bacteria according to the fatty acid makeup determined by a gas chromatographic method].		1975	1206145
[urease activity of proteus].		1975	1207522
[diagnosis of dysbacteriosis in infants].		1975	1208158
in vitro activity and pharmacokinetics in patients of cefamandole, a new cephalsoporin antibiotic.	cefamandole nafate, a new cephalosporin for parenteral use, was evaluated in vitro against 231 recent clinical isolates and in 12 patients. cefamandole had activity equivalent to cefazolin against staphylococcus aureus, escherichia coli, and klebsiella pneumoniae. cefamandole was more active than cephalothin or cefazolin against proteus mirabilis. both cefamandole and cefazolin were as active as cephalothin against s. aureus, were slightly more active against k. pneumoniae, and were considerably ...	1975	1211920