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antimicrobial selection for meningitis in young infants.organisms causing community-acquired meningitis in the first four months of life were reviewed. species of streptococcus and enterobacteriaceae were preponderant in the neonatal period, whereas s pneumoniae and haemophilus influenzae were preponderant after the first month of life. the enterobacteriaceae, other than salmonella, were not associated with meningitis after one month of age. implications for antimicrobial selection were considered.1979389034
in vitro comparison of synergism between cefamandole and gentamicin or tobramycin by the triple layer agar method with enzymatic inactivation.a synergistic effect was shown with gentamicin and tobramycin by means of a triple layer agar technique and enzymatic inactivation of cefamandole after only four hours' incubation. when the strain is sensitive to cefamandole and aminoglycosides, synergy is observed against all the strains studied (staphylococcus aureus, proteus, klebsiella, escherichia coli, enterobacter, and haemophilus influenzae). no significant difference was noted between the cefamandole-tobramycin and the cefamandole-genta ...1979389805
comparative in vivo activity of bacampicillin and amoxycillin.bacampicillin is an orally well-absorbed pro-drug of ampicillin giving high in vivo levels of the latter. its therapeutic activity was compared with that of amoxycillin in two experimental infection models in mice. the animals were infected with suspensions of escherichia coli iii and haemophilus influenzae 22863 intraperitoneally and treated orally four hours afterwards with one of the two compounds. the antibacterial activity of the compounds was determined as cd50 values or by making viable c ...1979389821
specific inhibition of macrophage migration inhibition factor by fucosylated glycolipid rm.the effects of glycolipids on the interaction of the mif (migration inhibition factor) with rat macrophages were examined using a migration inhibition assay system. mif activity was specifically blocked by fucosylated glycolipid rm [gal alpha 1-3gal(2-1 alpha fuc) beta 1-3galnac beta 1-3gal beta 1-4glc beta 1-1ceramide, (1978) j. biochem. 83, 85-90], but not by cytolipin r, hematoside, or blood group b active glycolipid [gal alpha 1-3gal(2-1 alpha fuc) beta 1-4glcnac beta 1-3gal beta 1-4glc beta ...1979389925
diagnosis of bacterial meningitis by gas-liquid chromatography. i. chemotyping studies of streptococcus pneumoniae, haemophilus influenzae, neisseria meningitidis, staphylococcus aureus, and escherichia coli.with the use of gas-liquid chromatographic techniques, the chemical characteristics of streptococcus pneumoniae type 3, escherichia coli, group b neisseria meningitidis, haemophilus influenzae type b, and staphylococcus aureus, organisms that commonly cause bacterial meningitis, were identified. the combination of lipid, carbohydrate, and lipopolysaccharide components provided discriminating markers for chemotyping these bacteria. e. coli had a high content of 17- and 19-carbon cyclopropane fatt ...1979390061
meningitis caused by haemophilus influenzae in infant rats: protective immunity and antibody priming by gastrointestinal colonization with escherichia coli.infant rats aged five to seven days were fed escherichia coli o75:k100:h5, e. coli o13:k92:h4, or saline and five weeks later were inoculated with haemophilus influenzae type b. the incidence of bacteremia and meningitis was significantly less (p less than 0.05) for rats fed e. coli that possessed k100 capsular antigen (cross-reactive with type b capsular antigen) than for rats fed e. coli k92 or saline. antibody to capsular antigen was not detectable in sera obtained from rats prior to challeng ...1979390062
[clinical results of cefuroxime (cxm) therapy in pediatric infections (author's transl)].cefuroxime, a new cephalosporin c antibiotic, was administered to 15 children with respiratory tract infection, urinary tract infection, or subcutaneous tumour. the following results were obtained. 1) cxm 30 approximately 100 mg/kg/day were used in treatment of respiratory tract infection. eight of the eleven patients treated responded to the therapy. 2) cxm 45 approximately 75 mg/kg/day were given to 3 patients with urinary tract infection. excellent results were obtained in all these cases. 3) ...1979390177
a satire on the influenza of 1803. 1979390272
human plasma angiotensinogen: a review of purification procedures.the current status of the purification and characterization of human angiotensinogen is reviewed. one problem encountered in the past has been the copurification of a protein with similar porperties. this protein has tentatively been designated alanine-protein. an efficient separation of angiotensinogen and alanine-protein was obtained on a zinc chelate column. alanine-protein has been purified and its amino acid and carbohydrate composition determined. the cooh-terminal amino acid and the nh2-t ...1979390363
[melanosomes from the biochemical viewpoint]. 1979391412
recurrence of otitis media after antibiotic therapy: comparison of cephradine and amoxycillin.the long-term effectiveness of cephradine and amoxycillin in the treatment of otitis media was evaluated in one hundred children ranging in age from 4 months to 14 years. the immediate clinical response was comparable in both treatment groups, but the recurrence rate during a 12-month follow-up period was considerably lower in the patients treated with cephradine. the incidence of side-effects was similar in the two groups.1979391628
update on non hospital-acquired pneumonias. 1979392574
in vivo and in vitro responses of cats sensitized with viable mycobacterium bovis (bcg).cats were injected subcutaneously with viable mycobacterium bovis (bcg), and immune responses were evaluated at various times after injection. the bcg injection produced fever, leukocytosis, neutrophilia, and lymphadenopathy of regional lymph nodes. intradermal tuberculin injection produced responses consistent with delayed type hypersensitivity reaction in the treated cats at postinoculation day 21. skin responses to tuberculin were not significant at postinoculation day 49. the cellular infilt ...1979393146
indirect sandwich enzyme-linked immunosorbent assay for rapid detection of haemophilus influenzae type b infection.we report the development and testing of an enzyme-linked immunosorbent assay with excellent sensitivity for the detection of haemophilus influenzae type b (hi(b)) antigen in clinical specimens from patients with hi(b) meningitis. the assay, an indirect sandwich technique, uses polystyrene balls as a solid phase and an alkaline phosphatase-labeled goat anti-rabbit globulin conjugate. specimens are incubated with polystyrene balls armed with burro anti-hi(b) antiserum, and recognition antibody is ...1979393714
[clinical experience of cefadroxil (bl-s 578) (author's transl)]. 1979393847
renal filtration, transport, and metabolism of low-molecular-weight proteins: a review. 1979393891
lung compliance and lung morphology following artificial ventilation in the premature and full-term rabbit neonate.rabbit neonates delivered on day 27--30 of gestation were subjected to intermittent positive pressure ventilation (ippv) for 60 min. tidal volume was standardized to 10 ml/kg, and the insufflation pressure required to maintain this tidal volume was recorded. the quasistatic compliance of the lung-thorax system, corrected for variations in body weight, was significantly lower in animals delivered on day 27--28 than in those delivered on day 29--30. immature animals with low lung-thorax complianc ...1979394314
[granulocyte defence against bacterial infection in diabetes mellitus with special reference to bactericidal activity].granulocytic defence against bacterial infection has been studied in a group of diabetic patients. with the skin chamber method markedly reduced leukocyte mobilization in vivo which was independent of metabolic compensation was found in all diabetic patients. investigation of phagocytic function of latex particles and bacterial killing of e. coli revealed firm dependence on metabolic regulation: in decompensated diabetes mellitus the two function tests were clearly pathological, whereas in the c ...1979394321
the histochemical pattern of acid phosphatase activity in mansonella ozzardi microfilariae from trinidad, west indies. 1979395745
[the molecular biology of aging -- 15: structure and function of the genetic apparatus in aging. ii. synthesis and metabolism of rna].with aging in different organs there are similar or tissue specific changes of the ribonucleic acids in respect of the quantity, the spectrum of different rna species and the metabolism of rna. among these processes the template function of the chromatin and the behaviour of the rna polymerases are important influencing factors. in aging the sensitivity of the rna synthesis against hormonal stimulation is decreased in the most cases. a survey about the results of many in vivo and in vitro experi ...1979395770
measure of immunoglobulin g-, m-, and a-specific titers against legionella pneumophila and inhibition of titers against nonspecific, gram-negative bacterial antigens in the indirect immunofluorescence test for legionellosis.a crude extract of escherichia coli o13:k92:h4 inhibited 97% of positive indirect immunofluorescence titers against a variety of gram-negative bacterial antigens while lowering legionella pneumophila titers in only 6% of sera from patients with suspected legionellosis. legionella-specific titers were the result of immunoglobulins g, m, and a, singly or in combination.1979397223
[utilization of a micromethod for the differentiation of haemophilus biotypes. relations with serotypes and antibiotypes (author's transl)].a micromethod utilizing paper discs impregnated with different substrates (minitek-system) permits differentiation of haemophilus and their biotypes. differentiation of biotypes presents an assured advantage: it is the only technic for an exact study of non typable h. influenzae strains and nad-dependent haemophilus strains. it is also a complement for study of capsulated h. influenzae. in an epidemiological aspect, this differentiation shows a evident predominance of biotypes i and ii for h. in ...1979398166
summary of laboratory studies on the antibacterial activity of cefaclor.laboratory aspects of cefaclor, a new orally-effective cephalosporin antibiotic, are summarized. on the basis of data from a variety of studies, the useful antibacterial spectrum of cefaclor is shown to include all classes of bacteria that are generally susceptible to cephalothin and cephalexin. against many enterobacteriaceae, haemophilus sp. and streptococcus pneumoniae, cefaclor has a significant potency advantage over cephalexin. bacteria that are susceptible to cefaclor are killed by concen ...1979398479
cefaclor compared with amoxycillin acute otitis media with effusion: a preliminary report.a double-blind, randomized clinical trial comparing cefaclor with amoxycillin in the treatment of acute otitis media with effusion (ome) in infants and children is being conducted at children's hospital of pittsburgh. although the randomization code has not yet been broken, the results of treating the first 55 children are reported, since they appear to be of interest. of the 62 ears with acute ome on which an initial tympanocentesis was performed, 41 positive cultures were isolated from the mid ...1979398480
characterization of rennin-like enzyme produced in submerged cultures of aspergillus niger. 1979400533
acute endotoxin shock in the dog and an attempt at its therapy.the present study aimed at monitoring of hemodynamic changes proceeding in a standard model of acute endotoxin shock in the dog, and mainly at an attempt at the therapy of its early phases. acute endotoxin shock represents a grave state with rapidly advancing changes in blood circulation, therefore we studied the effects of selected drugs, intended to regulate the circulation conditions in the course of shock. in a standard model in the dog, in which endotoxin shock had been induced by intraveno ...1979400547
systemic haemophilus influenzae disease: an overview. 1979370354
aryl-monoalkyl and cyclic triazenes: direct-acting mutagens.an aryl-monoalkyl triazene, methyl-p-tolyl triazene (mtt) and a cyclic triazene (delta2-triazoline) are direct-acting mutagens for salmonella typhimurium bacteria and for cell-free hemophilus influenzae dna. mtt causes reversion of the hisg46 base-substitution mutation, but no reversion of the hisd3052 frameshift mutation. induced mutation frequency is not strongly influenced by modifications in the genetic background of the s. typhimurium ames tester strains, but is mildly enhanced by the addit ...1979372794
[universal mechanism for regulating blood clotting and fibrinolysis]. 1979373283
cefuroxime in the treatment of lower respiratory tract infection.cefuroxime is a new parenteral antibiotic with a wider spectrum of activity than earlier cephalosporins and is particularly active against haemophilus influenzae, including strains resistant to ampicillin due to beta-lactamase production. from 18 centres, 274 patients suffering with 275 infections were treated with cefuroxime sodium using the standard regimen of 750 mg 8-hourly by intramuscular injection. the clinical results showed a 90% success rate in the patients with bronchopneumonia (105), ...1979373991
protein and ribonucleic acid syntheses in heat-damaged and heat-killed escherichia coli.protein and ribonucleic acid (rna) syntheses were measured in both lethally injured and thermally damaged viable cells after heating at lethal temperatures. immediately after heating, cells were incubated in growth media containing either [14c]leucine or [3h]uracil. the labeled cells were subsequently treated with penicillin. viable cells were shown to lyse, and the intact nonviable cells were collected by centrifugation. the results showed that after heating, protein and rna synthesis were rein ...1979374390
molecular nature of two haemophilus influenzae r factors containing resistances and the multiple integration of drug resistance transposons.the 36-megadalton haemophilus influenzae r plasmid phk539 was found to specify resistance to tetracycline (tc) and ampicillin (ap). it was shown by molecular hybridization studies and by electron microscopy that the plasmid phk539 contained the tetracycline translocation deoxyribonucleic acid (dna)segment (tntc) as well as the ampicillin translocation segment (tnap). the tnap was integrated in the stem of tntc. the 34-megadalton h. influenzae r plasmid pri234 carried a translocatable dna segment ...1979374398
studies in potential organo-fluorine antibacterial agents. part 2: synthesis and antibacterial activity of some new fluorine-containing 3.5-disubstituted isoxazoles.a series of new fluorine-containing 3,5-disubstituted aryl/alkylisoxazoles has been synthesized by the condensation of hydroxylamine with appropriate beta-diketones in the presence of pyridine and characterized by ir and 1h nmr spectral studies. these isoxazoles have been screened for their antibacterial activity against the gram positive bacteria, staphylococcus albus, streptococcus nonhemolyticus and the gram negative bacterium escherichia coli.1979375248
insect axopods.using the elctron microscope we have found axopods, a cell organelle previously undescribed in multicellular animals, in the lower malpighian tubule of the insect. rhodnius prolixus. the axopods, which are 0.2 to 0.8 micrometer in diameter and 10 or more micrometer in length, derive from the luminal surface of the tubule and contain an array of 1 to about 46 microtubules each. these microtubules arise within the cell near the cell junctions or near clumps of mitochondria. uric acid crystals whic ...1979370127
[epidemiological, clinical and evolutive aspects of haemophilus influenzae type b meningitis in africa]. 197916108276
[bacitracin as a selective factor for the isolation of h. influenzae in primary culture from polymicrobial products]. 197916296485
efficacy of lithium carbonate in alcoholism: case studies. 1979273295
therapeutic use of omeprazole for refractory stress-induced gastric mucosal hemorrhage. 19791597047
[a danish medical delegation in the people's republic of china]. 19791145893
petit mal epilepsy.petit mal epilepsy is primarily a disorder of childhood. it is a comparatively rare type of seizure and is relatively benign. it rarely causes demonstrable evidence of pathologic cerebral changes, except in patients who have frequent attacks of petit mal status. patients with petit mal epilepsy are prone to develop major motor (grand mal) seizures. therefore, concurrent administration of petit mal and major motor anticonvulsants is recommended.1979414604
skin thickness in the therapeutically irradiated breast.skin thickening of the breasts of 22 women undergoing excision biopsy of a breast cancer and subsequent radiation therapy to 5,000 rad is considered. the skin thickness of the treated breast returned to normal in 17 of 22 patients studied. of the 17, nearly 60% returned to normal in 2 years, over 80% in 3 years, and the rest by 4 years. the period of follow-up was less than 4 years in the five patients with residual skin thickening. the alterations in skin thickness are consistent with the histo ...1979414591
glucagon secretion in two patients with autoantibodies to glucagon-producing cells. 1979352890
[letter: cooperation between clinics and laboratory]. 19791145859
[gudden, huguenin, hitzig. brain psychiatry in burghözli 1869--1879]. 1979352821
[dissertations of prof. heinrich buess' candidates for the doctor's degree at basle university]. 1979352816
intestinal parasites in south carolina--a three year study. 1979273122
a regulatory system controlling the production of cytochrome aa3 in neurospora crassa.the mitochondria of the cyt-2-1, cya-3-16, cya-4-23 and 299-1 nuclear mutants and the [mi-3] and [exn-5] cytoplasmic mutants of neurospora crassa are deficient in cytochrome aa3, while the cyb-1-1 and cyb-2-1 mutants have mitochondrial b-cytochrome deficiencies. however, the mitochondria from cyb-1-1 cyt-2-1, cyb-1-1 [mi-3] and cyb-2-1 [mi-3] double mutants contain 30% to 50% of the amount of cytochrome aa3 that is present in mitochondria from wild-type; i.e. cyb-1-1 and cyb-2-2 act as suppresso ...1979216899
[a course in public health or a course in community medicine]. 19791145786
phineas w. whiting (1887--1978). 1979352796
[cytological studies of the anthers, microsporogenesis and gametogenesis of fertile wheat plants and those with cytoplasmic male sterility]. 19791145734
[studies on the repaired filling. composite resin to composite resin (author's transl)]. 1979275349
[prosthetic principles in endosseous implantation (i) and implantation-based dentures (ii)].the prosthetic principles in intraosseous implantation and of the implanted replacement are surveyed and an indication is given of the important prosthetic indications. the significance of proper positioning of the implant and shaping of the implanted replacement are specially dealt with.1979352675
survey of curriculum and instruction: continuing education courses in pain control.pain and anxiety control is taught at the continuing education level in a large number of diverse courses. this paper reports the results of a survey of those courses offered in 1976. the majority of courses centered on the use of inhalation or intravenous sedation. relatively few courses were offered on the other aspects of pain and anxiety control. very little attempt is being made at formally evaluating the competence of participants in these courses. few courses appear to adequately cover th ...1979273039
[the surface of dental enamel treated in vitro with fluoride-containing toothpaste]. 1979272961
mandibular deficiency syndrome. iii. surgical advancement of the deficient mandible in growing children: treatment results in twelve patients.the surgical-orthodontic correction of mandibular deficiency in growing children (8 to 16 years of age) can be employed to achieve excellent results. mandibular advancement by a modified sagittal osteotomy proves to be an acceptable procedure with good skeletal stability. dentofacial growth following surgery will be harmonious and not adversely affected. direction of growth varies, with the mandibular plane angle becoming more vertical with an increasing mandibular plane angle.1979273187
[neuro-vegetative regulation of the cardiovascular system. role of the functional independence of the right and left hemisections]. 1979352780
[spinocellular carcinoma of the hand].the proper treatment of squamous cell carcinoma of the hand is surgical only. radical cure and preservation of function need not exclude one another if the following points are considered: praeoperative biopsy and intraoperative pathological examination, consideration of the degree of malignancy and the possibilities of surgical reconstruction.1979352849
[prosthetic reconstruction after right-side maxillary resection]. 1979352759
effect of clonidine on sympathetic nervous activity in hydralazine-treated hypertensive patients. 1979352707
an outbreak of beta-lactamase producing haemophilus influenzae (biotype iii) on a geriatric ward. 19806182239
mast cells as a possible source of haemophilus influenzae-induced changes in plasma and lung histamine levels.histidine decarboxylase activity and histamine levels of peritoneal mast cells were enhanced 4 days after intraperitoneal haemophilus influenzae vaccination of rats. incubation of the cells with propranolol (3.4 x 10(-4) m) resulted in histamine release and an increased histidine decarboxylase activity. histidine decarboxylase activity and histamine release were more increased in the presence of propranolol in mast cells obtained from h. influenzae-vaccinated rats. an increased mediator release ...19806153378
urinary tract infection caused by haemophilus parainfluenzae.a case of haemophilus parainfluenzae urinary tract infection is reported, with clinical history and bacteriologic data. other reports of this organism causing urinary tract infection could not be found. the importance of correlating data from clean-catch urine microscopic analysis, gram stain, and culture is emphasized, together with the possible modes of spread in a compromised host.19806153501
facilitation of histamine release in the haemophilus influenzae vaccinated experimental animal [proceedings]. 19806153543
phenotypic and genetic variation in the susceptibility of haemophilus influenzae type b to antibodies to somatic antigens.haemophilus influenzae type b (h.i.b) has been investigated with respect to phenotypic and genetic variations resulting in differential susceptibility to bactericidal antibody. previous studies had shown that after growth in infected rats or in dialysate of rat serum, h.i.b strain eag became more resistant to the bactericidal activity of antisomatic antibody. we now report that a similar phenotypic shift occurs when strain eag is incubated with dialysate of human serum, that the increased resist ...19806153662
the effects of haemophilus influenzae vaccination on anaphylactic mediator release and isoprenaline-induced inhibition of mediator release.the influence of haemophilus influenzae on anaphylactic mediator release from ovalbumin-sensitized isolated guinea pig lungs was investigated. lungs from h. influenzae-vaccinated animals released prostaglandins and thromboxanes following a smaller dose of ovalbumin than was effective in non-vaccinated animals. histamine release was significantly increased in 4 day-vaccinated animals but not 1 or 10 days after vaccination, while broncho-constriction was potentiated in 1 and in 4 day-vaccinated an ...19806154589
preparation of a nontoxic and immunogenic polysaccharide fraction from a haemophilus influenzae phenol-water extract.a phenol-water extract from haemophilus influenzae type a was hydrolyzed to decrease the toxicity without affecting the antigenicity of the preparation. we used partial hydrolysis for 15 h with ion exchangers in the presence of chloroform. the lipid fraction was collected into the organic solvent. the preparation obtained from the aqueous solution was designated the polysaccharide fraction. rhamnose, glucose, galactose, mannose, and glucosamine were the major components of the polysaccharide fra ...19806156911
specific restriction endonucleases from haemophilus influenzae jc9. 19806158837
bacteriophage n3 of haemophilus influenzae. iii. characterization of bacteriophage n3 dna.dna extracted from phage n3 grown in haemophilus influenzae strain jc9 was examined by velocity and equilibrium centrifugation, electron microscopy and thermal melting curves. this double stranded dna, molecular weight 26x10(6) daltons, has continuous single strands at 13x10(6) daltons as shown by alkaline sucrose gradient centrifugation. the duplex form readily aggregates in neutral salt solutions at even moderate ionic strength. aggregation may be due to n3 dna having "sticky" ends. cscl equil ...19806158842
bacteriophage n3 of haemophilus influenzae. iv. intracellular events during infection by haemophilus influenzae phage and transfection by its dna.intracellular events following infection of competent haemophilus influenzae cells by n3 phage or transfection by dna from phage were examined. after infection by whole phage three forms of intracellular phage dna were observed by sedimentation velocity analysis. these forms are probably twisted circles, open circles and linear duplexes. in transfection only about 15% of the phage dna is efficiently taken up by the competent cells. after entry of phage dna into wild-type cells in transfection th ...19806158843
whipple's disease: a case with circulating immune complexes.a patient with whipple's disease was studied for 56 wk from diagnosis, during which time he received continuous antibiotic therapy. intramucosal bacillary bodies detected by electron microscopy disappeared within 12 wk and a threefold fall in antibody titer to hemophilus influenza type b bacillus occurred during this period. circulating immune complexes of igg class were consistently detected during the first 28 wk of treatment but not subsequently. igm class immune complexes were detected at a ...19806160077
pathogenesis of sendasi virus infection in mice. on the possible role of interferon on the development of disease.intraperitoneally (i.p.) injected interferon prolonged the survival time of mice inoculated intranasally (i.n.) with sendai virus and reduced the mortality in mice inoculated i.n. with haemophilus influenzae. moderate concentrations of interferon were demonstrated in homogenized lungs of sendai virus infected mice as long as the virus was present. similar concentrations could be produced by i.p. injection of sendai virus or interferon. alveolar macrophages from mice treated i.p. with interferon ...19806160724
intravenous cefotaxime in children with bacterial meningitis.thirteen children with meningitis due to haemophilus influenzae, beta-haemolytic streptococcus group b, streptococcus pneumoniae, staphylococcus epidermidis, neisseria meningitidis, escherichia coli, or pseudomonas aeruginosa and who had been unsuccessfully treated with other antibiotics or had causative organisms which were resistant to available antibiotics were treated with intravenous cefotaxime. nine children were cured; in one case infection (with a different organism) recurred but a furth ...19806101414
mechanisms of ampicillin resistance in haemophilus influenzae from respiratory tract.13 of 100 consecutive isolates of haemophilus influenza obtained from respiratory specimens over the six months to june, 1979, had diminished sensitivity to ampicillin. 6 of the 13 strains produced beta-lactamase, whilst the remaining 7 had no evidence of this enzyme, either in whole cells or in extracts prepared by sonication. the minimum inhibitory concentration of ampicillin for the penicillinase-negative strains ranged from 1 mg/l to 8 mg/l on repeated testing with a carefully controlled aga ...19806101737
pneumococcal infection of the lung. 19806102270
use of selective media in bacteriological investigation of patients with chronic suppurative respiratory infection. 19806102681
ampicillin resistance in haemophilus influenzae. 19806103289
potential hazard of discontinuing chloramphenicol once sensitivity results are available in haemophilus meningitis. 19806103409
ampicillin resistance in haemophilus influenzae. 19806104149
ampicillin resistance in haemophilus influenzae. 19806104150
haemophilus influenzae, ampicillin sensitivity, and inoculum size. 19806105320
haemophilus influenzae, ampicillin sensitivity, and inoculum size. 19806105321
haemophilus infections in cystic fibrosis. 19806105423
haemophilus influenzae, ampicillin sensitivity, and inoculum size. 19806105540
pneumococcal vaccine and otitis media.after an acute attack of otitis media 827 children aged 3 months to 6 years were assigned randomly to receive either 14-valent pneumococcal polysaccharide vaccine or a control vaccine (haemophilus influenzae type b capsular polysaccharide). in children older than 6 months serum antibody responses to most of the vaccine polysaccharides were satisfactory. the response to type 6a was poor. correspondingly, no clinical protection was seen below 6 months of age or against otitis media caused by group ...19806106735
multiple resistant haemophilus influenzae and parainfluenzae in west germany. 19806106867
[cardiac tamponade and chambered pericardial effusion complicating hemophilus influenzae pericarditis (author's transl)].an unusual case of a 9 year old girl with primary pericarditis and cardiac tamponade due to hemophilus influenzae is reported. meningitis or manifestations in other organs could be excluded. despite pericardial drainage for three weeks beginning at the 11th day of illness, a chambered pericardial effusion developed, which could be localized more exactly by cross-sectional echocardiography than by axial computerized tomography.19806107851
haemophilus influenzae type b resistant to ampicillin and chloramphenicol in an orphanage in thailand. 19806108393
herpes simplex infection after needle aspiration of a lymph node. 19806243204
disseminated herpes simplex associated with h. influenzae infection in a previously healthy child. 19806244376
cytomegalovirus and dual infection in infants.in four unrelated infants without underlying immunodeficiency, dual infections with cytomegalovirus (cmv) and another microorganism developed. the patients included the following: (1) a 3-month-old girl with congenital cmv and perinatal cutaneous herpes simplex virus; (2) a 5-week-old girl with cmv and pneumocystis carinii; (3) a 12-week-old girl with cmv and haemophilus influenzae meningitis; and, (4) a 2 1/2-month-old girl with cmv and escherichia coli meningitis. in all four cases, the patien ...19806244804
purification and properties of hindii and hindiii endonucleases from haemophilus influenzae rd. 19806246330
clavulanic acid and cp-45,899: a comparison of their in vitro activity in combination with penicillins. 19806247316
[evaluation of the criteria used for the interruption of treatment in bacterial meningitis (persistent pleocytosis and hyper-cervicospinal fluid proteins (author's transl)].among 809 patients with bacterial meningitis persistent pleocytosis greater than 60 white blood, cells/mm3, after 10 days or more of therapy, was found in 25 patients and persistent hypercervicospinal fluid proteins greater than 70 mg/dl in 24. in 14 patients there was an association of these disturbances. all cases, except one, were adequately treated. persistent pleocytosis and hyper-cervicospinal fluid proteins, uncommon inmeningococcal meningitis, were frequent in pneumococcal and more frequ ...19806248985
cp-45,899 in combination with penicillin or ampicillin against penicillin-resistant staphylococcus, haemophilus influenzae, and bacteroides.cp-45,899 is a new, semisynthetic beta-lactamase inhibitor. when tested alone, cp-45,899 displayed only weak antibacterial activity, with the notable exception of its potent action against penicillin-susceptible and -resistant neisseria gonorrhoeae. a combination of 3.12 microgram of cp-45,899 per ml with 3.12 microgram of ampicillin per ml, tested in broth cultures, inhibited ca. 90% of resistant staphylococcus and haemophilus influenzae strains; similar data were obtained in a variety of media ...19806249192
in vitro antimicrobial activity of cefoperazone, cefotaxime, moxalactam (ly127935), azlocillin, mezlocillin, and other beta-lactam antibiotics against neisseria gonorrhoeae and haemophilus influenzae, including beta-lactamase-producing strains.minimum inhibitory concentrations and agar disk diffusion tests were determined on clinical isolates of beta-lactamase-positive and beta-lactamase-negative neisseria gonorrhoeae and haemophilus influenzae with the newer beta-lactam antibiotics, cefoperazone, cefotaxime, moxalactam (ly127935), azlocillin, mezlocillin, and piperacillin, and with seven older beta-lactam antibiotics. all the drugs were active against beta-lactamase-negative strains of n. gonorrhoeae and h. influenzae. the drug most ...19806249195
restriction endonucleases and their recognition sequences. 19806249680
[rapid diagnosis of respiratory virus infections in children. respiratory syncytial virus demonstrated by the immunofluorescent technic]. 19806250259
treatment of acute exacerbations of chronic bronchitis with cefotaxime: a controlled clinical trial. 19806252154
comparative in vitro activities of cefotaxime and ceftizoxime (fk749): new cephalosporins with exceptional potency.cefotaxime and its desacetoxymethyl derivative, ceftizoxime (previously known as fk749), are both extremely active against a wide spectrum of bacteria. in the present comparative study, the activity of ceftizoxime exceeded that of cefotaxime by a factor of four or more for strains of klebsiella, enterobacter, providencia, serratia, and bacteroides; the only species for which the activity of cefotaxime exceeded that of ceftizoxime by a factor of four was vibrio cholerae. against other species, th ...19806252829
in vitro activities of cefotaxime and moxalactam (ly127935) against haemophilus influenzae.the in vitro activities of two new beta-lactam antibiotics, cefotaxime and moxalactam (ly127935), were compared with those of cefamandole, cefoxitin, cefuroxime, and ampicillin against both beta-lactamase-producing and non-beta-lactamase-producing isolates of haemophilus influenzae. both cefotaxime and ly127935 were highly active against all isolates irrespective of beta-lactamase production.19806252832
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