Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| diamine oxidase and polyamine oxidase activities in normal and transformed cells. | 1. the activity of diamine oxidase (ec 1.4.3.6) in normal rat kidney cells and in normal rat kidney cells transformed by avian sarcoma virus (b77 strain) growing in tissue culture varies with the stage of growth. there is an initial stimulation of activity by 24h after seeding, followed by a steep decline during exponential growth (48-72h). enzyme activity decreases even further as the cells reach saturation density (confluence) after 4 days in culture when the activity in normal rat kidney cell ... | 1979 | 106846 |
| the methylenetetrahydrofolate-mediated biosynthesis of ribothymidine in the transfer-rna of streptococcus faecalis: incorporation of hydrogen from solvent into the methyl moiety. | 1979 | 106850 | |
| transducing activity of bacteriophage spp1. | 1979 | 106856 | |
| discontinuous variation in hepatic uridine diphosphate glucuronyltransferase toward androsterone in wistar rats. a regulatory factor for in vivo metabolism of androsterone. | 1979 | 106857 | |
| oxonol dyes as monitors of membrane potential. their behavior in photosynthetic bacteria. | the reponses of oxonol dyes to single and multiple single turnovers of the photosynthetic apparatus of photosynthetic bacteria have been studied, and compared with the responses of the endogenous carotenoid pigments. the absorbance changes of the oxonols can be conveniently measured at 587 nm, because this is an isosbestic point in the 'light-minus-dark' difference spectrum of the chromatophores. the oxonols appear to respond to the light-induced 'energization' by shifting their absorption maxim ... | 1979 | 103582 |
| stimulation of keratocyte metabolism by products of lymphoid cells. | products of leukocytes were found to activate cultures of keratocytes, manifested by the increased incorporation of thymidine or leucine. the keratocyte activation capacity crosses the species barriers between rabbit, monkey, and human. the level of secreted keratocyte-activating factor(s) (kaf) depends on the stimulation of the leukocytes. thus unstimulated rabbit leukocytes produced very little or no kaf, whereas significant levels were produced by leukocytes stimulated with lipopolysaccharide ... | 1979 | 106022 |
| direct comparison of the subtilisin-like intracellular protease of bacillus licheniformis with the homologous enzymes of bacillus subtilis. | intracellular serine proteases of bacillus licheniformis and bacillus subtilis are closely related. | 1979 | 106040 |
| influence of the lactose plasmid on the metabolism of galactose by streptococcus lactis. | streptococcus lactis strain dr1251 was capable of growth on lactose and galactose with generation times, at 30 degrees c, of 42 and 52 min, respectively. phosphoenolpyruvate-dependent phosphotransferase activity for lactose and galactose was induced during growth on either substrate. this activity had an apparent k(m) of 5 x 10(-5) m for lactose and 2 x 10(-2) m for galactose. beta-d-phosphogalactoside galactohydrolase activity was synthesized constitutively by these cells. strain dr1251 lost th ... | 1979 | 106044 |
| mutagenicity studies with x-ray-contrast media, analgesics, antipyretics, antirheumatics and some other pharmaceutical drugs in bacterial, drosophila and mammalian test systems. | as part of our investigation into mutagenic effects of environmental compounds, we studied 21 pharmaceuticals most frequently sold in west germany: 6 x-ray-contrast media, 13 analgesics, antipyretics and antirheumatics, 1 central stimulant, and 1 antidepressant. they were studied in different bacterial, drosophila and mammalian test systems. 4 of these 21 compounds could be detected as mutagens in one of the test systems. namely: 1,2-dichloroethane induced an increase in the frequency of recessi ... | 1979 | 106272 |
| response of oxidative phosphorylation in liver of protein-energy malnourished rats. | state 3, state 4 respiratory rates, respiratory control ratio (rcr = state 3/state 4), adp/o ratio and swelling in salt medium were determined in liver mitochondria from three groups of rats: group 1--controls; group 2--energy-restricted, and group 3--protein-deficient. experiments were carried out between 3 and 5 weeks and between 7 and 9 weeks after initiation of the experimental diets. state 3 respiration of mitochondria from group 2 rats was reduced after 3-5 weeks on the experimental diet ... | 1979 | 106343 |
| complement and coagulation: causative considerations in contrast catastrophies. | earlier studies suggest that adverse reactions to injected radiographic contrast media are idiosyncratic. in an attempt to gain a better understanding of pathophysiologic events underlying these reactions, rabbit models injected with lethal dose ranges of a cholangiographic contrast material were studied. these animals showed activation of both the complement and coagulation systems. externally applied heat potentiated complement consumption and increased mortality. depleting complement componen ... | 1979 | 105577 |
| dual action of adrenergic system on the regulation of thyrotrophin secretion in the male rat. | the effect of graded doses of drugs modifying adrenergic activity on basal and cold-stimulated tsh secretion was studied in male rats. alpha-methyl-p-tyrosine (ampt) (16 h before 30 min cold-exposure), phenoxybenzamine (1 h), ca-fusarate (1 h) and diethyldithiocarbamate (ddc) (1 and 18 h) dose-dependently depressed the cold-stimulated tsh secretion. the effect of reserpine (24 h) was not significant. clonidine (1 h), dihydroxyphenyl-serine (dops) (1 h), noradrenaline (na) (1 h), and l-dopa (1 h) ... | 1979 | 105532 |
| [serotype characteristics of clinical strains of pseudomonas aeruginosa]. | a total of 348 p. aeroginosa strains isolated from patients with pulmonary and pleural diseases were studied, and 87% of the test showed the possibility of their serotyping with the use of group-specific agglutinating antisera. serogroups ii, iii, iv were found to be prevalent among the strains isolated from patients with bronchopulmonary pathological states. correlations between definite groups of p. aeroginosa in their sensitivity to antibiotics were established; thus, the cultures belonging t ... | 1979 | 105521 |
| the effect of dl-2-bromopalmitate on the utilization of palmitic acid by rat granular pneumocytes. | the effect of dl-2-bromopalmitate (brpa), an analogue of palmitic acid (pa), on the utilization of this fatty acid by rat lungs was investigated by a combination of anatomic and biochemical methods. the experiments were performed in vitro on two types of preparations, isolated perfused lungs and lung slices. in the isolated lung preparation the substrate reached the lung via the capillaries, in lung slices via the alveolar epithelium. electron microscope autoradiography showed that brpa depresse ... | 1979 | 105465 |
| [determination of cholera vibrion enterotoxin by an aggregate hemagglutination method]. | 1979 | 105503 | |
| non-immunological regression of dimethylbenz(a) anthracene-induced experimental keratoacanthomas in the rabbit. | in 9 rabbits, with a total of 17 experimental keratoacanthomas, a search has been made for immune-mediated mechanisms which could possibly be involved in the spontaneous regression of these tumours. immunofluorescence studies did not reveal significant staining patterns. with skin tests, using autologous extracts prepared in three different ways, no delayed cutaneous hypersensitivity reactions were observed. | 1979 | 104893 |
| [isolation of treponemas from the colon of pigs with clinical dysentery]. | optimal culture conditions in artificial nutritive media were determined for a defined avirulent strain of treponema hyodysenteriae and for four field strains of treponemas in pigs with clinical dysentery. the treponemas were isolated with the use of milliporous filters with pores of 0.3 micrometer in diameter, which were located on the surface of blood agar. no significant difference in the influence of equine, bovine or sheep blood on the growth of treponemas was determined. the commercial amo ... | 1979 | 105448 |
| [effectiveness of paraformaldehyde foam in continuous disinfection of poultry bedding and dried liquid waste of pigs]. | in laboratory experiments 24-hour cultures of poultry strains e. coli, staphylococcus, pseudomonas on paper carriers without an agar coat and with it, after 6-hour exposure in dilutions from 10(-4) to 0, were devitalized by paraformaldehyde foam. the bacillus strain was devitalized only after 24-hour exposure. after adding paraformaldehyde foam in an amount of 0.6% of the weight into litter under a multiplier flock of layers four months before expedition, and after adding paraformaldehyde foam i ... | 1979 | 105450 |
| [effect of feeding pelleted feed on the level of volatile fatty acids in the digestive tract of sheep]. | in an experiment with wethers we investigated the effect of complete pelleted feed ration on the concentration of volatile fatty acids in the rumen and intestinal tract. the animals consumed daily 1,300 g of dry matter of a diet which contained 41.81% of meadow hay, 25.28% of barley, 15.37% of sawdust, 14.98% of molasses, 1.32% of urea and 1.24% of a vitamin-mineral supplement for a period of six months. the pelleted diet increased the total amount of volatile fatty acids, the content of propion ... | 1979 | 105451 |
| inhibition of bacillus subtilis growth and sporulation by threonine. | a 1-mg/ml amount of threonine (8.4 mm) inhibited growth and sporulation of bacillus subtilis 168. inhibition of sporulation was efficiently reversed by valine and less efficiently by pyruvate, arginine, glutamine, and isoleucine. inhibition of vegetative growth was reversed by asparate and glutamate as well as by valine, arginine, or glutamine. cells in minimal growth medium were inhibited only transiently by very high concentrations of threonine, whereas inhibition of sporulation was permanent. ... | 1979 | 104959 |
| effects of local anesthetics on bacterial cells. | the membrane effects of chlorpromazine, nupercain, tetracain, and procain were studied using bacillus cereus, b. megaterium, b. subtilis, and streptococcus faecalis, protoplasts from s. faecalis, and isolated membranes from b. subtilis. chlorpromazin, nupercain, and tetracain produced characteristic micromorphological alterations after treatment for 5 to 30 min at ph 7.0 and 20 degrees c; the membrane staining pattern changed from asymmetric to symmetric, complex mesosome-like structures appeare ... | 1979 | 104970 |
| the primary structure of lactobacillus casei thymidylate synthetase. iii. the use of 2-(2-nitrophenylsulfenyl)-3-methyl-3-bromoindolenine and limited tryptic peptides to establish the complete amino acid sequence of the enzyme. | 1979 | 105005 | |
| rapid, sensitive and specific electron capture-gas chromatographic method for the quantitation of 6-chloro-2-(1-piperazinyl) pyrazine in biological fluids. | a highly specific and sensitive gas chromatographic method for the determination of 6-chloro-2-(1-piperazinyl)pyrazine (mk-212), a central serotonin-like agent, in biological fluids is described. mk-212 and a related internal standard are extracted into benzene from an alkaline solution, back-extracted into acid and then re-extracted into benzene at an alkaline ph. the amines are converted to the trifluoroacetyl derivatives (characterized by gas-liquid chromatography-mass spectrometry), chromato ... | 1979 | 105011 |
| early steps in specific tumor cell lysis by sensitized mouse t lymphocytes. iii. resolution of two distinct roles for calcium in the cytolytic process. | 1979 | 105046 | |
| differentiated b lymphocytes. potential to express particular antibody variable and constant regions depends on site of lymphoid tissue and antigen load. | b cells have the potential to respond to an antigen by producing antibodies with a variety of variable and constant regions. we have quantitatively analyzed b-cell potential at the single cell level to determine the effect of lymphoid tissue site and antigen load on the expression of variable and constant regions. concerning variable region expression, although the total frequency of b-cell precursors for phosphorylcholine is similar between nonimmune spleen and gut-associated peyer's patch tiss ... | 1979 | 105075 |
| diagnosing gonococcal urethritis in males: experience in an oklahoma venereal disease clinic. | 1979 | 105092 | |
| acute leukemia following prolonged cytotoxic agent therapy. | 1. nine patients in whom acute non-lymphoblastic leukemia (anll) developed following prolonged alkylating agent therapy are described. five of the patients received no radiotherapy. the conditions treated were: hodgkin's disease (four patients), primary amyloidosis, primary macroglobulinemia, malignant lymphoma, multiple myeloma, and carcinoma of the tonsil. 2. prior to the advent of chemotherapy, this complication was not observed in large series of patients with lymphoproliferative disorders a ... | 1979 | 105227 |
| pressure-dependent changes in nuclei and the process origins of the endothelial cells lining schlemm's canal. | monkeys eyes were fixed with glutaraldehyde in vivo at positive intraocular pressure of 35 or 25 mm hg and compared with eyes fixed without a positive pressure gradient, with the use of light microscopy and transmission and scanning electron microscopy. the entire endothelial lining of the inner wall of schlemm's canal ballooned or distended toward the external wall of the canal at positive intraocular pressure. characteristic nuclear shapes were identified and appeared to result from the increa ... | 1979 | 103860 |
| [dna-membrane interaction during induction of reparative synthesis by methylnitrosourea]. | 1979 | 104853 | |
| effect of nitroglycerin on vulnerability to ventricular fibrillation during myocardial ischemia and reperfusion. | the effect of nitroglycerin on vulnerability to ventricular fibrillation was examined in 44 chloralose-anesthetized dogs. in 19 animals ventricular fibrillation threshold was measured before and during a 10 minute period of occlusion of the left anterior descending coronary artery followed by abrupt release of occlusion. fibrillation threshold was determined using the single stimulus and train of stimuli methods. the influence of nitroglycerin on vulnerability was assessed with and without preve ... | 1979 | 104608 |
| restricted posterior parietal lesions in the rhesus monkey and performance on visuospatial tasks. | monkeys with lesions restricted to the inferior parietal lobule or the banks and depths of the superior temporal sulcus were tested on a route-following task. these areas are considered on neuroanatomical grounds to be homologous to parts of the human posterior parietal cortex, where lesions produce profound spatial disorientation. the operated monkeys were impaired on the route task, thus confirming at the behavioural level the anatomical predictions of comparability between parietal cortex in ... | 1979 | 103604 |
| formation of hcg in the human fetoplacental unit. | hcg and beta-hcg were determined in umbilical arterial and venous blood immediately after spontaneous term delivery. hcg and beta-hcg are present in higher concentrations in arterial than in venous umbilical cord blood. the data are consistent with the hypothesis that hcg and beta-hcg are produced in the fetal compartment of the human fetoplacental unit, with a larger contribution of the female fetus as compared with the male. | 1979 | 95667 |
| [biological activity of bordetella and salmonella endotoxins]. | 1979 | 228129 | |
| survival and herpes virus production of normal and xeroderma pigmentosum fibroblasts after treatment with formaldehyde. | the survival of excision-deficient and of excision-proficient (variant) skin fibroblasts from xeroderma pigmentosum (xp) donors was about 5 times and twice, respectively, more sensitive to formaldehyde (fa) treatment than that of skin fibroblasts from healthy and xp heterozygote donors. the capacity of fa-treated host cells to further support herpes virus (hsv) replication was also more sensitive to fa in xp12be (group a) than in normal (kd) cells. an important recovery of this capacity occurred ... | 1979 | 228186 |
| endogenous viral genes are non-essential in the chicken. | dna sequences homologous to the genomes of type c retroviruses are widespread among vertebrates. ten genetic loci containing endogenous viral dna sequences have been documented in the white leghorn chicken alone. six of these genetic loci are associated with the production of virus or of viral proteins in embryonic fibroblasts (refs 2--4, and s.m.a., l, b. crittenden and e.g.b., in preparation) and one of the loci may be expressed in the erythroblasts of 5-day-old embryos. the abiquitous presenc ... | 1979 | 228201 |
| reciprocal responses to tilt of neurones within both fore- and hindlimb regions of deiters' nucleus. | in decerebrate cats with cerebellum intact the frequency response of 102 neurons located within the lateral vestibular nucleus (lvn) to sinusoidal stimulation of vestibular receptors was analyzed. positional sensitive units, showing a reciprocal pattern of response to lateral tilting, characterized by an excitation during ipsilateral and a depression during contralateral tilt, were equally found in the rostroventral (forelimb) and dorsocaudal (hindlimb) divisions of the lvn. no unit was found to ... | 1979 | 228242 |
| response pattern of cat hippocampal neurons to stimulation of the septal area during sleep and waking. | 1979 | 228329 | |
| the to strains of theiler's viruses cause "slow virus-like" infections in mice. | intracerebral inoculation of mice with tissue culture-adapted to strains of theiler's mouse encephalomyelitis viruses results in a clinical disease consisting of spastic paralysis due to demyelination after a lengthy incubation period. thus, in effect, these ordinary picornaviruses are capable of causing a slow infection in their natural host, the mouse. in addition, through the use of tissue culture-adapted virus stocks, virus content in mouse tissues now can be accurately quantified by standar ... | 1979 | 228588 |
| dibutyryl cyclic adenosine 3',5'-monophosphate: its role in regulation of cat brain extracellular fluid. | the role of dibutyryl cyclic adenosine 3',5'-monophosphate (db camp) in influencing the water content of the cat's gray and white matter was evaluated by intracoritcal injection of 20 micrio l of 2 x 10(-1) to 2 x 10(-6)m solution of db camp. cholera toxin, a stimulator of adenylate cyclase, also was tested. concentrations of db camp less than 10(-3)m failed to produce significant change in brain water content, while concentrations greater than 10(-2)m produced 31.5% +/- 8% and 17.3% +/- 3.6% in ... | 1979 | 228644 |
| carcinogenic chemicals enhance mouse leukemia virus infection in contact-inhibited culture: a new simple method of screening carcinogens. | carcinogenic chemicals enhanced infection in contact-inhibited cells with mouse leukemia virus. a correlation was found between the enhancing effects and the carcinogenicities of the 40 chemicals tested. the tumor promoter 12-o-tetradecanoylphorbol-13-acetate did not enhance viral infection. | 1979 | 228846 |
| possible origin of the bluetongue epidemic in cyprus, august 1977. | possible origins of an epidemic of bluetongue in cyprus in august 1977 have been analysed. first outbreaks occurred simultaneously in the south-east of the famagusta district and on the north coast of the kyrenia district respectively. although the epidemic was due to type 4, which had been responsible for the previous outbreak in 1969, no evidence of persistance of virus could be found. imports of domestic animals in the past year were not implicated since the imported cattle were introduced on ... | 1979 | 229164 |
| response of adenosine cyclic 3',5'-monophosphate level in rabbit neutrophils to the chemotactic peptide formyl-methionyl-leucyl-phenylalanine. | 1979 | 229400 | |
| structure/activity studies of flavonoids as inhibitors of cyclic amp phosphodiesterase and relationship to quantum chemical indices. | 1979 | 229402 | |
| receptor-mediated uptake of lipoprotein-cholesterol and its utilization for steroid synthesis in the adrenal cortex. | 1979 | 229524 | |
| reversal of pancuronium with edrophonium. | edrophonium was administered as a bolus of 2, 10 or 50 mg (0.03, 0.14 and 0.71 mg/kg) to antagonize neuromuscular block after pancuronium in man. neuromuscular transmission was measured using "train-of-four" stimulation. recovery started within 1 min, was maximum at 2 min and was then followed by a plateau of slow continued improvement. the degree of recovery increased with larger doses of edrophonium and also was related to the total amount of pancuronium administered although reversal was atte ... | 1979 | 229740 |
| fate of herpes simplex virus in lymphocytes from inflammatory joint effusions. i. failure of the virus to grow in cultured lymphocytes. | the ability of lymphocytes isolated from the blood and synovial effusions of patients with rheumatoid arthritis to support the growth of herpex simplex virus (hsv) was studied. whereas blood lymphocytes supported virus growth, effusion lymphocytes were usually non-permissive. lymphocytes obtained from the effusions of patients with other forms of inflammatory arthritis or suspected viral arthritis commonly failed to support the growth of hsv, but the virus grew in effusion lymphocytes from patie ... | 1979 | 229777 |
| encephalomyocarditis virus-specific polypeptide p22 is involved in the processing of the viral precursor polypeptides. | 1979 | 230074 | |
| changes in growth and morphology of human gliomas and fibroblasts cultured in d-valine medium. | human fibroblasts and cells cultured from a glioblastoma multiforme and and oligodendroglioma were grown in standard tissue culture medium and in a medium in which d-valine was substituted for l-valine (dvm). growth of all three types of cells was inhibited in dvm. morphological changes of cells cultured in dvm also occurred: many fibroblasts became stellate-shaped and the oligodendroglioma cells had fewer processes. these findings indicate that dvm can not be used to decrease fibroblastic conta ... | 1979 | 230323 |
| inert gas measurement of heterogeneous myocardial perfusion. | 1979 | 232845 | |
| acute angiotensin ii-mediated restoration of distal renal artery pressure in renal artery stenosis and its relationship to the development of sustained one-kidney hypertension in conscious dogs. | 1979 | 233086 | |
| virus precursor shedding from mammary tumour cells. | 1979 | 233256 | |
| etiology of infantile enteritis in south africa. | infantile enteritis constitutes a major health problem in developing countries. several investigations into the etiology of this condition among various south african populations have been undertaken during the past few years. recent studies of black urban infants have revealed that salmonellae, shigellae, enterotoxigenic enterobacteriaceae, and rotaviruses play a relatively minor role in infantile enteritis. on the other hand, all studies, including a number performed several years ago, have de ... | 1979 | 221438 |
| association of circulating retroviral gp70-anti-gp70 immune complexes with murine systemic lupus erythematosus. | endogenous retroviral gp70 was investigated as a participant in the pathogenesis of a lupus-like disease that spontaneously develops in four kinds of mice (nzb, nzb x w mrl/1, and male bxsb). sera from these strains contain a heavy form of gp 70 that varies in sedimentation rates from 9s to 19s in sucrose density gradient analysis and appears with the onset of disease and persists throughout its course. immunologically normal strains of mice do not develop rapidly sedimenting gp70 by 8-10 mo of ... | 1979 | 221610 |
| route of herpesvirus spread traced with aid of dna-cleaving enzymes. | 1979 | 221697 | |
| [regulation of pituitary hormone secretion: regulation of acth secretion]. | 1979 | 221705 | |
| migration of human vascular endothelial and smooth muscle cells. | migration of endothelial and smooth muscle cells was studied in vitro by measuring the increase in surface area at specific time intervals of confluent cell colonies advancing under agarose gels that contained both morgan's medium 199 and variuos types of sera. first passage cultures of endothelial cells or 3 to 6 passage smooth muscle cells were plated into wells punched in agarose gels, at a seeding density of 50,000 cells per well. at zero time the size of the cell colonies was 35.4 sq. mm. + ... | 1979 | 221740 |
| regulation of corneal collagenase production: stimulation of serially passaged stromal cells by blood mononuclear cells. | after three or more passages, stromal cell outgrowths from explants of normal rabbit corneas and from corneas previously burned with alkali did not produce collagenase until they were stimulated by the addition of rabbit blood-derived mononuclear cells or media conditioned by them. normal stromal cells required stimulation by lymphocytes or their products from alkali-burned animals, whereas those from alkali-burned corneas were stimulated by lymphocytes from either normal or alkali-burned rabbit ... | 1979 | 222470 |
| secretory granules of the duodenal enterochromaffin cells of the cat. | 1979 | 222959 | |
| haemophilus influenzae periplasmic protein which binds deoxyribonucleic acid: properties and possible participation in genetic transformation. | a protein which binds to either single-stranded or double-stranded deoxyribonucleic acid (dna) but not to ribonucleic acid has been isolated by osmotic shock treatment of growing cells. this periplasmic protein differs from the principal intracellular binding protein in its greater thermolability and by the absence of salt-induced cooperativity in its interaction with single-stranded dna. certain mutant strains of haemophilus influenzae defective in the dna suptake steps of genetic transformatio ... | 1979 | 225299 |
| development and experimental evaluation of a contrast medium for computed tomographic examination of the liver and spleen. | a lipoid based contrast material containing 53% of ethiodized oil in emulsion form was developed for computed tomography (ct) of the liver and spleen and tested in rabbits and monkeys. an intravenous dose of 0.2 ml/kg selectively opacified the liver and spleen, resulting in an average increase of 23 emi units (500 scales) in the attenuation of the liver and a higher increase in the attenuation of the spleen. when injected into rhesus monkeys with carcinogen induced hepatomas there was a signific ... | 1979 | 217896 |
| serotonergic activation of tonic-type enteric neurons in guinea pig small bowel. | 1. electrical stimulation of interganglionic fiber tracts of auerbach's plexus released a chemical substance, which produced a slow epsp associated with an increase in input resistance in the postsynaptic neuron. 2. this effect of fiber tract stimulation was mimicked by microiontophoretic application of serotonin (5-ht) to the neurons. both the endogenous transmitter substance and exogenous 5-ht produced membrane depolarization, both increased the input resistance of the neuron, both reduced or ... | 1979 | 217976 |
| the biosynthesis of basement membrane components in a cell-free system derived from mouse parietal yolk sac carcinoma cells. | 1979 | 218051 | |
| strand-specific attachment of avidin-spheres to double-stranded poliovirus rna. | poliovirus-specific double-stranded rna molecules containing covalently attached protein were coupled with a biotin ester through the protein moiety. subsequent interaction of the rna-biotin with avidin attached to electronopaque plastic spheres led to the formation of complexes that were easily visualized in the electron microscope. avidinspheres were associated only with one end of the rna-biotin molecules, as seen in the electron microscope. avidin-sphere attachment to poliovirus double-stran ... | 1979 | 218216 |
| regional localization of the gene for human phosphoribosylpyrophosphate synthetase on the x chromosome. | sixty-eight independent hybrid clones were isolated after irradiated normal human lymphocytes were fused with chinese hamster fibroblasts lacking hypoxanthine-guanine phosphoribosyltransferase activity. the cells were grown under selective conditions requiring retention of the x chromosome-linked locus for human hypoxanthine-guanine phosphoribosyltransferase. the frequency and patterns of cotransference of human phosphoribosylpyrophosphate synthetase with the selected marker and with additional ... | 1979 | 218284 |
| radiometric detection of haemophilus in simulated blood cultures. | the radiometric detection of various haemophilus species was studied in simulated blood cultures and in blood culture media without added blood, but supplemented with nicotinamide-adenine dinucleotide (nad) or hemin, or both. haemophilus aphrophilus was the only species studied that was radiometrically detectable without added blood or nad. all other species studied (haemophilus influenzae, haemophilus parainfluenzae, haemophilus haemolyticus, and haemophilus parahaemolyticus) required either ad ... | 1979 | 218444 |
| enhancement of biochemical transformation of mammalian cells by herpes simplex virus following nitrosomethylurea treatment. | a quantitative assay for the biochemical transformation of thymidine kinaseless mouse cells (n cia ci10 cells) to an enzyme-positive phenotype by herpes simplex virus has been used to examine the effect of the carcinogen nitrosomethylurea on cell transformation. exposure of cells to the chemical carcinogen, followed by virus infection, resulted in enhancement of transformation when compared to that seen with virus or chemical alone. enhancement occurred after doses of nitrosomethylurea that were ... | 1979 | 218720 |
| clinical evaluation of a radioimmunoassay for beta-msh-related peptides (lipotrophins) in human plasma. | 1979 | 218751 | |
| quantitation of the various termini generated by type ii restriction endonucleases using the polynucleotide kinase exchange reaction. | parameters of the polynucleotide kinase-catalyzed exchange reaction between [gamma-32p]atp and 5'-phosphoryl dnas have been measured with the termini generated by the following endonucleases: ecori (berkner, k. l., and folk, w. r. (1977) j. biol. chem. 252, 3176-3184), hpa ii, bamhi, and hindiii (external termini); hindii and hpa i (blunt terminal); hae ii and hha i (internal termini). in every case, exchange is reproducible and proportional to the number of termini. however, in most cases, the ... | 1979 | 218943 |
| rotaviral immunity in gnotobiotic calves: heterologous resistance to human virus induced by bovine virus. | the possibility of immunizing human infants against rotaviruses, which cause severe dehydrating diarrheal disease, may depend on the use of a related rotavirus, derived from another animal species, as a source of antigen. to test the feasibility of this approach, calves were infected in utero with a bovine rotavirus and challenged with bovine or human type 2 rotavirus shortly after birth. infection in utero with bovine rotavirus induced resistance to diarrheal disease caused by the human virus a ... | 1979 | 216077 |
| ventricular aneurysms complicating coxsackievirus group b, types 1 and 4 murine myocarditis. | suckling swiss webster mice were inoculated with 10(4)tcd50 of coxsackieviruses, group b types 1 or 4. virulent necrotizing myocarditis resulted in 185 infected mice. of the latter group, three (14.3%) nurslings on the 17th and 23rd day after inoculations had left ventricular aneurysms postmortem. none of 61 concurrently matched control mice developed aneurysms. ventricular aneurysm is a suggested but previously undocumented complication of murine, and possibly human necrotizing transmural coxsa ... | 1979 | 215340 |
| the effect of sleep upon the transmission of afferent activity in the somatic afferent system. | macaque monkeys were trained to fall asleep while sitting in a primate chair with their heads restrained. a gentle vibratory stimulus was delivered to the glabrous skin of the hand; it did not provoke awakening or change the sleep cycle of the macaque. postcentral neuronal response to the amplitude of a sine wave mechanical stimulus and neuronal spontaneous activity were observed repetitively during all the phases of normal night sleep cycles. one hundred six neurons which could be entrained by ... | 1979 | 217703 |
| effects of haemophilus influenzae vaccination on the (para-)sympathic-cyclic nucleotide-histamine axis in rats. | to determine whether haemophilus influenzae could be a factor in human atopy its effects were studied on the (para-)sympathic cyclic nucleotide-histamine axis in rats. haemophilus influenzae vaccination induced changes in the cholinergic system compatible with higher cyclic gmp levels and enhanced histamine release. the authors suggest an involvement of the cholinergic system in haemophilus influenzae vaccination effects. | 1979 | 216288 |
| herpes simplex virus type i from a patient with radiculoneuropathy. | herpes simplex virus type i was isolated from the csf of a patient with atypical lumbosacral pain. the features of this case are unusual and important in light of the current understanding of herpes-simplex-virus-associated neurologic disease. | 1979 | 214589 |
| the influence of gestational age and size on the absorption of d-xylose and d-glucose from the small intestine of the human neonate. | d-xylose absorption (using the one-hour blood levels) and active d-glucose absorption (calculated from changes in transmural electrical potential difference) have been measured after intraduodenal infusion of the appropriate sugar, in groups of neonates who were full-term or preterm, and who were in addition either appropriately sized for gestational age, or growth-retarded in utero. the one-hour d-xylose blood levels were significantly lower in preterm infants, and were even lower in the growth ... | 1979 | 261523 |
| the kallikrein-kininogens-kinins system in the brown-norway rat. | the brown-norway rat is deficient in plasma kallikrein and kininogens, making it particularly useful in studies on the role of the kinins system in some physiological and physiopathological processes. | 1979 | 261573 |
| [experimental research on the regenerative capacity of fetal tissue of the extremities injured by teratogenic insult to vascular bases]. | 1979 | 261943 | |
| [histopathological aspects and macrophage reactivity in rats with guerin's t8 viral tumor after treatment with corynebacterium parvum]. | 1979 | 262125 | |
| the effect of nutritional state on neuromuscular transmission in the rat. | 1. evoked end-plate potentials (e.p.p.s) were recorded in phrenic nerve-hemidiaphragm preparations from rats which had been subjected to periods of dietary restriction. 2. the mean quantum content of the first e.p.p. of trains of e.p.p.s was significantly increased after 1 week of dietary restriction in 30-day-old but not in 110-day-old rats. 3. the mean quantum content of plateau e.p.p.s elicited at a frequency of 10 hz was not significantly affected by brief periods of dietary restriction in e ... | 1979 | 220414 |
| [sociological aspects in breast cancer. illness and death are part of being human]. | 1979 | 254323 | |
| comparative activities of ampicillin, epicillin and amoxycillin in vitro and in vivo. | the antibacterial activities of three aminopenicillins ampicillin, epicillin and amoxycillin were compared in vitro and in vivo. the minimum inhibitory concentrations (mic) of the three penicillins were very similar and the compounds were active against non-beta-lactamase-producing strains of escherichia coli, salmonella and shigella species, proteus mirabilis, haemophilus influenzae and neisseria gonorrhoeae. streptococci including streptococcus faecalis, and non-beta-lactamase-producing staphy ... | 1979 | 256524 |
| feline eosinophilic granuloma complex: a clinicoepidemiologic study of 32 cases. | 1979 | 257955 | |
| [comparison of the antibacterial activity of ticarcillin with other antibacterial agents (author's transl)]. | antibacterial activity of ticarcillin was determined in comparison with that of sulbenicillin, amoxicillin, cefuroxime, clindamycin and metronidazole against anaerobic bacteria which have been isolated from various clinical materials in this hospital. growth of more than 90% of gram-negative anaerobic rod bacteria was inhibited by ticarcillin at its concentration of 100 micrograms/ml. strains resistant to ticarcillin showed cross resistance against both sulbenicillin and amoxicillin. antibacteri ... | 1979 | 258675 |
| antibiotic sensitivity and synergism of 'penicillin-tolerant' staphylococcus aureus. | 15 staphylococcus aureus strains were isolated from 15 patients with staphylococcal bacteremia. eight of these strains were shown to be tolerant for cloxacillin. cloxacillin-tolerant strains were also tolerant for most of the cephalosporins tested except for cephapirin. strains were not tolerant for clindamycin and gentamicin. penicillin-tolerant staphylococci showed a high degree of synergism between gentamicin and cloxacillin or cephalothin and gentamicin. | 1979 | 260698 |
| [human science. self-awareness. (3). awareness of the ego]. | 1979 | 260804 | |
| [effect of heat on accidental organochlorine insecticide residues in a non-poisonous mushroom (níscalo) (lactarius deliciosus l)]. | 1979 | 263644 | |
| experimental studies on the biological properties of bordetella pertussis. | 1979 | 262507 | |
| [serological study of postvaccinal measles immunity in the absence of a booster effect and in measles foci]. | 1979 | 262711 | |
| characteristics of the event-related brain potential to noxious thermal stimulation in man. | 1979 | 262716 | |
| significance of lipid peroxidation in the genesis of chronic vasospasm following rupture of an intracranial aneurysm. | 1979 | 290253 | |
| anti-androgen tsaa-291. iv. effects of the anti-androgen tsaa-291 (16 beta-ethyl-17 beta-hydroxy-4-oestren-3-one) on the secretion of gonadotrophins. | effects of the anti-androgen tsaa-291 on the gonadotrophin secretion were studied. (1) a single subcutaneous or oral administration of tsaa-291 and its caproate induced the ovulation in the proestrous rat of which the spontaneous ovulation was blocked by the treatment with chlorpromazine. (2) a single subcutaneous administration of tsaa-291 at 2.4 mg/kg to the adult male rat induced only a slight elevation in the serum lh and fsh levels at 30 min after the administration. successive intramuscula ... | 1979 | 294107 |
| cochlear nonlinear phenomena in two-tone responses. | 1979 | 294691 | |
| the ultrastructure of surfaces of positively identified cells in the human urinary sediment. a correlative light and scanning electron microscopic study. | surfaces of cells in the urinary sediment, postively identified by light microscopy (lm) were studied by scanning electron microscopy (sem). about 35% of benign urothelial cells were characterized by the presence of short, stubby microvilli (mv). about 60% of such cells had surface microridges, and the remaining cells had surface blebs. squamous epithelial cells were characterized primarily by microridges or by a mixture of microridges with short microvilli. urothelial cancer cells had various s ... | 1979 | 294764 |
| childhood pneumonia at goroka hospital. | we have reviewed the clinical presentation of pneumonia to the goroka paediatric ward. in comparison to survivors, children dying from pneumonia more often (p less than 0.05) had malnutrition (weight-for-age under 80%), anaemia (haemoglobin under 9g%), and a marked leucocytosis (total white cell count over 30,000 cells per c.m.m.). children dying from pneumonia had been ill for longer and had been given more antibiotics prior to admission. there was no significant difference between children dyi ... | 1979 | 299332 |
| haemophilus influenzae type d pneumonia. | 1979 | 310640 | |
| serum chloramphenicol levels and the intramuscular bioavailability of several parenteral formulations of chloramphenicol in ruminants. | 1979 | 419516 | |
| the effect of oxazepam on ocular readaptation time. | the readaptation time (rat) is the interval during which a person exposed to a bright intense light flash cannot perceive a given target. in this study the target used was an optokinetic pattern and the elicited nystagmus (okn) was registered with electrooculography (eog), thus giving an objective registration of rat. oxazepam in therapeutic doses was given to five healthy subjects and the rat and serum concentrations of the drug were registered simultaneously at different time intervals. an alm ... | 1979 | 419971 |
| influence of somatostatin on glucagon- and epinephrine-stimulated hepatic glucose output in the dog. | glucose kinetics were measured using [3-3h]glucose in conscious dogs during the infusion of: 1) glucagon alone; 2) glucagon plus somatostatin with insulin replacement; 3) epinephrine alone; and 4) epinephrine plus somatostatin with insulin and glucagon replacement. infusion of glucagon alone resulted in a 10-15 mg/dl rise in plasma glucose and a transient 45% rise in glucose production. when somatostatin and insulin were added, a four- to fivefold greater rise in plasma glucose and glucose produ ... | 1979 | 420283 |
| permeability of human erythrocyte membrane vesicles to alkali cations. | the permeability of inside-out and right-side-out vesicles from erythrocyte membranes to inorganic cations was determined quantitatively. using 86rb as a k analog, we have measured the rate constant of 86rb efflux from vesicles under equilibrium exchange conditions, using a dialysis procedure. the permeability coefficients of the vesicles to rb are only about an order of magnitude greater than that of whole erythrocytes. furthermore, we have measured many of the specialized transport systems kno ... | 1979 | 420826 |
| distribution of o6-methylguanine in rat dna following pretreatment in vivo with methylnitrosourea. | 1979 | 421194 | |
| anaphylaxis in guinea-pig peripheral airways in vitro. | the contributions made by histamine, prostaglandins (pg) and slow reacting substance (srs-a) to anaphylactic contractions in isolated guinea-pig lung were investigated. histamine, pgf2alpha and srs-a induced isometric contractions in lung parenchymal strips and in tracheal smooth muscle. the effective concentrations of the autacoids were the same in lung strips and tracheas. anaphylactic contractions in lung strips from bovine serum albumin sensitised animals were not affected by mepyramine (5 x ... | 1979 | 421743 |